TENM3 Antibody Cat. No.: 8151
TENM3 Antibody
Immunohistochemistry of TENM3 in mouse brain tissue Immunofluorescence of TENM3 in mouse brain tissue with with TENM3 antibody at 5 μg/mL. TENM3 antibody at 20 μg/mL.
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
TENM3 antibody was raised against a 17 amino acid peptide near the amino terminus of human TENM3. IMMUNOGEN:
The immunogen is located within the first 50 amino acids of TENM3.
TESTED APPLICATIONS: ELISA, IF, IHC-P, WB
September 29, 2021 1 https://www.prosci-inc.com/tenm3-antibody-8151.html TENM3 antibody can be used for detection of TENM3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. APPLICATIONS: Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
TENM3 antibody is human, mouse and rat reactive. TENM3 antibody is predicted to not SPECIFICITY: cross-react with other members of the TENM family.
POSITIVE CONTROL: 1) Cat. No. 1210 - HEK293 Cell Lysate
Predicted: 297 kDa PREDICTED MOLECULAR WEIGHT: Observed: 300 kDa
Properties
PURIFICATION: TENM3 antibody is affinity chromatography purified via peptide column.
CLONALITY: Polyclonal
ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: TENM3 antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION: 1 mg/mL
TENM3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one STORAGE CONDITIONS: year.
Additional Info
OFFICIAL SYMBOL: TENM3
ALTERNATE NAMES: Teneurin transmembrane protein 3, teneurin-3, ODZ3, TEN-M3, TNM3, MCOPCB9
ACCESSION NO.: NP_001073946
PROTEIN GI NO.: 122937400
GENE ID: 55714
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
September 29, 2021 2 https://www.prosci-inc.com/tenm3-antibody-8151.html The teneurin transmembrane protein 3 (TENM3) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2). TENM3 is BACKGROUND: expressed in cartilaginous cells during postnatal growth in mice (3), as well as the adult eye and optic stalk (4). Homozygous null mutations in TENM3 causes microphthalmia in humans (5).
1) Ben-Zur T and Wides R. Mapping homologs of Drosophila odd oz (odz): Doc4/Odz to REFERENCES: mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25. Genomics 1999; 58:102-3.
2) Rubin BP, Tucker RP, Martin D, et al. Tenurins: a novel family of neuronal cell surface proteins in vertebrates, homologous to the Drosophila pair-rule gene Ten-m. Dev. Biol. 1999; 216:195-209.
3) Murakami T, Fukunaga T, Takeshita N, et al. Expression of Ten-m/Odz3 in the fibrous layer of madibular condylar cartilage during postnatal growth in mice. J. Anat. 2010; 217:236-44.
4) Ben-Zur T, Feige E, Motro B, et al. The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles. Dev. Biol. 2000; 217:107-20.
ANTIBODIES FOR RESEARCH USE ONLY.
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September 29, 2021 3 https://www.prosci-inc.com/tenm3-antibody-8151.html