Anti-SHPK Monoclonal Antibody, Clone 4E8 (DCABH-1083) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-SHPK monoclonal antibody, clone 4E8 (DCABH-1083) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to CARKL

Antigen Description The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.

Immunogen Recombinant full length protein (Human NP_037408).

Isotype IgG1

Source/Host Mouse

Species Reactivity Human

Clone 4E8

Purity Protein G purified

Conjugate Unconjugated

Applications WB, IHC-P, ICC/IF

Format Liquid

Size 100 μl

Buffer pH: 7.30; Preservative: 0.02% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 1% BSA

Preservative 0.02% Sodium Azide

Storage store at -20°C. Avoid freeze / thaw cycles.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name SHPK sedoheptulokinase [ Homo sapiens ]

Official Symbol SHPK

Synonyms SHPK; sedoheptulokinase; carbohydrate kinase like , CARKL; SHK; carbohydrate kinase-like protein; CARKL; FLJ32478;

Entrez Gene ID 23729

Protein Refseq NP_037408

UniProt ID Q9UHJ6

Chromosome Location 17p13

Function ATP binding; nucleotide binding; sedoheptulokinase activity; transferase activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]