T.A. Kostromina the LANGUAGE of MEDICINE AS a MEANS OF
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General Pathomorpholog.Pdf
Ukrаiniаn Medicаl Stomаtologicаl Аcаdemy THE DEPАRTАMENT OF PАTHOLOGICАL АNАTOMY WITH SECTIONSL COURSE MАNUАL for the foreign students GENERАL PАTHOMORPHOLOGY Poltаvа-2020 УДК:616-091(075.8) ББК:52.5я73 COMPILERS: PROFESSOR I. STАRCHENKO ASSOCIATIVE PROFESSOR O. PRYLUTSKYI АSSISTАNT A. ZADVORNOVA ASSISTANT D. NIKOLENKO Рекомендовано Вченою радою Української медичної стоматологічної академії як навчальний посібник для іноземних студентів – здобувачів вищої освіти ступеня магістра, які навчаються за спеціальністю 221 «Стоматологія» у закладах вищої освіти МОЗ України (протокол №8 від 11.03.2020р) Reviewers Romanuk A. - MD, Professor, Head of the Department of Pathological Anatomy, Sumy State University. Sitnikova V. - MD, Professor of Department of Normal and Pathological Clinical Anatomy Odessa National Medical University. Yeroshenko G. - MD, Professor, Department of Histology, Cytology and Embryology Ukrainian Medical Dental Academy. A teaching manual in English, developed at the Department of Pathological Anatomy with a section course UMSA by Professor Starchenko II, Associative Professor Prylutsky OK, Assistant Zadvornova AP, Assistant Nikolenko DE. The manual presents the content and basic questions of the topic, practical skills in sufficient volume for each class to be mastered by students, algorithms for describing macro- and micropreparations, situational tasks. The formulation of tests, their number and variable level of difficulty, sufficient volume for each topic allows to recommend them as preparation for students to take the licensed integrated exam "STEP-1". 2 Contents p. 1 Introduction to pathomorphology. Subject matter and tasks of 5 pathomorphology. Main stages of development of pathomorphology. Methods of pathanatomical diagnostics. Methods of pathomorphological research. 2 Morphological changes of cells as response to stressor and toxic damage 8 (parenchimatouse / intracellular dystrophies). -
Role of Brain Stimulation and the Blood–Brain Interface
biomolecules Review Monitoring and Modulating Inflammation-Associated Alterations in Synaptic Plasticity: Role of Brain Stimulation and the Blood–Brain Interface Maximilian Lenz 1,*, Amelie Eichler 1 and Andreas Vlachos 1,2,3,* 1 Department of Neuroanatomy, Institute of Anatomy and Cell Biology, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany 2 Center Brain Links Brain Tools, University of Freiburg, 79110 Freiburg, Germany 3 Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany * Correspondence: [email protected] (M.L.); [email protected] (A.V.) Abstract: Inflammation of the central nervous system can be triggered by endogenous and exogenous stimuli such as local or systemic infection, trauma, and stroke. In addition to neurodegeneration and cell death, alterations in physiological brain functions are often associated with neuroinflammation. Robust experimental evidence has demonstrated that inflammatory cytokines affect the ability of neurons to express plasticity. It has been well-established that inflammation-associated alterations in synaptic plasticity contribute to the development of neuropsychiatric symptoms. Nevertheless, diagnostic approaches and interventional strategies to restore inflammatory deficits in synaptic plasticity are limited. Here, we review recent findings on inflammation-associated alterations in synaptic plasticity and the potential role of the blood–brain interface, i.e., the blood–brain barrier, Citation: Lenz, M.; Eichler, A.; in modulating synaptic plasticity. Based on recent findings indicating that brain stimulation promotes Vlachos, A. Monitoring and plasticity and modulates vascular function, we argue that clinically employed non-invasive brain Modulating Inflammation-Associated stimulation techniques, such as transcranial magnetic stimulation, could be used for monitoring and Alterations in Synaptic Plasticity: modulating inflammation-induced alterations in synaptic plasticity. -
Histologische Versagensanalyse Von 114 Metall/Metall-Großkopfhüftendoprothesen
Aus der Orthopädischen Universitätsklinik der medizinischen Fakultät der Otto-von-Guericke-Universität Magdeburg Direktor: Prof. Dr. med. C. H. Lohmann Histologische Versagensanalyse von 114 Metall/Metall-Großkopfhüftendoprothesen D i s s e r t a t i o n zur Erlangung des Doktorgrades Dr. med. (doctor medicinae) an der Medizinischen Fakultät der Otto-von-Guericke-Universität Magdeburg vorgelegt von Tina Müller aus Magdeburg Magdeburg Oktober 2016 Dokumentationsblatt Müller, Tina: Histologische Versagensanalyse von 114 Metall/Metall-Großkopfhüftendoprothesen – 2016. – 76 Bl.: 24 Abb., 6 Tab. Die Studie analysierte klinisch, radiologisch, histologisch und anhand intraoperativer Befunde 114 Versagensfälle einer modularen Metall/Metall-Großkopfhüftendoprothese. Alle unter- suchten Patienten zeigten bereits frühzeitig nach Implantation der Primärprothese klinische Symptome, welche auf eine Prothesenlockerung hindeuteten. Schon während der Revisi- onsoperation waren charakteristische Veränderungen im periprothetischen Gewebe makro- skopisch sichtbar. Die gewonnenen Gewebeproben wurden in 5%igem Formalin fixiert. Die histologischen Proben wurden mit Hämatoxylin-Eosin gefärbt, mit monoklonalen anti-CD3- sowie anti-CD68-Antikörpern markiert und auf spezifische Gewebsveränderungen untersucht. Die histomorphologischen Untersuchungen wiesen in der Mehrheit der Fälle eine Fremdkör- perreaktion auf. Mikroskopisch wurden in der Monozyten-/Makrophagenzytologie schwarze Metallpartikel gefunden. Es lässt sich vermuten, dass es bei Verwendung verschiedener -
Craniodental Anatomy of a New Late Cretaceous Multituberculate Mammal from Udan Sayr, Mongolia
University of Louisville ThinkIR: The University of Louisville's Institutional Repository Electronic Theses and Dissertations 8-2014 Craniodental anatomy of a new late cretaceous multituberculate mammal from Udan Sayr, Mongolia. Amir Subhash Sheth University of Louisville Follow this and additional works at: https://ir.library.louisville.edu/etd Part of the Anatomy Commons, and the Medical Neurobiology Commons Recommended Citation Sheth, Amir Subhash, "Craniodental anatomy of a new late cretaceous multituberculate mammal from Udan Sayr, Mongolia." (2014). Electronic Theses and Dissertations. Paper 1317. https://doi.org/10.18297/etd/1317 This Master's Thesis is brought to you for free and open access by ThinkIR: The nivU ersity of Louisville's Institutional Repository. It has been accepted for inclusion in Electronic Theses and Dissertations by an authorized administrator of ThinkIR: The nivU ersity of Louisville's Institutional Repository. This title appears here courtesy of the author, who has retained all other copyrights. For more information, please contact [email protected]. CRANIODENTAL ANATOMY OF A NEW LATE CRETACEOUS MULTITUBERCULATE MAMMAL FROM UDAN SAYR, MONGOLIA By Amir Subhash Sheth B.A., Centre College, 2010 A Thesis Submitted to the Faculty of the School of Medicine of the University of Louisville in Partial Fulfillment of the Requirements for the Degree of Master of Science Department of Anatomical Sciences and Neurobiology University of Louisville Louisville, Kentucky August 2014 CRANIODENTAL ANATOMY OF A NEW LATE CRETACEOUS MULTITUBERCULATE MAMMAL FROM UDAN SAYR, MONGOLIA By Amir Subhash Sheth B.A., Centre College, 2010 A Thesis Approved on July 18th, 2014 By the Following Thesis Committee: ________________________________ (Guillermo W. -
Inflammation
Inflammation II. 1 Definitions Inflammation is defined as local reaction of vascularized living tissue to local injury, characterized by movement of fluid and leukocytes from the blood into the extravascular space. According the time frame is divided into two categories: acute and chronic. Function: • destroys, dilutes or walls off injurious agents • one of body’s non-specific defense mechanisms • begins the process of healing and repair 1.1 Acute Inflammation Rapid onset, usually short duration Microscopy • neutrophils dominate • other cellular elements are also involved (monocytes/macrophages, platelets, mast cells) • protein rich exudate, especially fibrin Associations • necrosis • pyogenic bacteria 1.2 Chronic Inflammation Usually long duration, but in some cases may be short. May follow acute inflammation or may have an insiduous onset (without an apparent prelude of acute inflammation). Microscopy • mononuclear cells dominate – lymphocytes – plasma cells (plasmocytes) – monocytes/macrophages • other cellular elements are also involved (eosinophils, neutrophils in active“ inflammation)1 ” • In granulomas are typical Langhans cells, large, multinuclear elements on the periphery of tuberculous granulomas. Nuclei are sometimes arranged in a horseshoe shape formation. Foreign body cells are similar, usually smaller, the horseshape formation of nuclei is not present. Both these elements are modified macrophages. • evidence of healing — fibroblasts, capillaries, fibrosis Associations • long term stimulation of immune system, autoimmunity • viral infections -
SURGICAL TECHNIQUE PIP Total Joint – Dorsal Approach Table of Contents
® Ascension SURGICAL TECHNIQUE PIP Total Joint – Dorsal Approach Table of Contents Introduction Humanitarian Device .................................................................................................................................................................2 Indications ................................................................................................................................................................................2 Contraindications ......................................................................................................................................................................2 Warnings and Precautions ......................................................................................................................................................... 3 Keys to Successful PIP Replacement ...........................................................................................................................................4 Surgical Technique Preoperative Assessment .......................................................................................................................................................... 5 Step 1: Skin Incision, Capsular Opening and Exposure ................................................................................................................ 5 Step 2: Medullary Canal Opening and Alignment ........................................................................................................................6 Step 3: First -
Protective Effects of Zinc-L-Carnosine /Vitamin E on Aspirin- Induced Gastroduodenal Injury in Dogs
PROTECTIVE EFFECTS OF ZINC-L-CARNOSINE /VITAMIN E ON ASPIRIN- INDUCED GASTRODUODENAL INJURY IN DOGS MASTER’S THESIS Presented in Partial Fulfillment of the Requirements for the Master of Science Degree in the Graduate School of the Ohio State University By Mieke Baan, DVM, MVR ***** The Ohio State University 2009 Master’s Examination Committee: Professor Robert G. Sherding, Adviser Professor Stephen P. DiBartola Associate Professore Susan E. Johnson Approved by Adviser Veterinary Clinical Sciences Graduate Program ! Copyright by Mieke Baan 2009 ABSTRACT Zinc plays a role in many biochemical functions, including DNA, RNA, and protein synthesis. The dipeptide carnosine forms a stable complex with zinc, which has a protective effect against gastric epithelial injury in-vitro and in-vivo. This randomized double-blinded placebo-controlled study investigated the protective effects of zinc-L-carnosine in combination with alpha-tocopheryl acetate (vitamin E) on the development of aspirin-induced gastrointestinal (GI) lesions in dogs. Eighteen mixed-breed dogs (mean 20.6 kg) were negative for parasites, and had normal blood work evaluations, and gastroduodenoscopic exams. On days 0 – 35, dogs were treated with 1 tablet (n=6) or 2 tablets (n=6) of 30 mg zinc-L-carnosine/ 30 IU vitamin E q12h PO, or a placebo (n=6). On days 7 – 35, all dogs were given 25 mg/kg buffered aspirin q8h PO. Endoscopy was performed on Days -1, 14, 21, and 35, and GI lesions (hemorrhages, erosions, or ulcers) were scored using a 12-point grading scale. Repeated measures ANOVA was used for statistical evaluation. The significance level was set at p ! 0.05. -
Cancer Lung: an Unusual Presentation
www.ijmpo.org CA se Re po RT Cancer lung: An unusual presentation Shankar L. Jakhar, ABSTRACT Rohitashwa Dana, D. P. Punia Phalanx bone metastasis as the initial manifestation of lung cancer is a rare presentation. Department of Radiotherapy, A 70-year-old man presented with swelling and pain in his right ring finger. He had no Mathura Das Mathur Hospital, other complaints or abnormal findings on clinical examination. A right hand radiograph Dr. Sampurnanand Medical showed an osteolytic lesion in the first phalanx of the ring finger. Fine needle aspiration College, Jodhpur, Rajasthan, cytology of the swelling suggested a metastatic adenocarcinoma. A skeletal survey, India hematological, biochemical, and other radiological tests were found to be normal, except for an opacity seen in the right lung midzone. A bronchoscopic biopsy revealed Address for correspondence: adenocarcinoma of the lung. Dr. Shankar Lal Jakhar, Department of Radiotherapy, Mathura Das Mathur Hospital, Key words: Bone metastasis, cancer lung, phalanx Jodhpur, Rajasthan, India. E-mail: [email protected] DOI: 10.4103/0971-5851.65343 INTRODUCTION of the lung. A bone scan showed increased uptake in the proximal phalanx of the right ring finger. We planned Bone metastases from the lung cancer may occur early in systemic chemotherapy and palliative radiotherapy to the the clinical course and are usually discovered to exist with finger with a nonsteroidal analgesic for relieving pain. pain.[1,2] The spine and ribs are often the earliest sites of bone metastases, whereas, the skull, femur, humerus, and scapula DISCUSSION are involved later.[3] Metastases to the hands are rare events with around 200 cases reported in the literature.[4-8] They Bone metastasis in distal parts of the extremities is [9-11] comprise only 0.1% of all osseous metastases. -
Mcqs and Emqs in Surgery
1 The metabolic response to injury Multiple choice questions ➜ Homeostasis B Every endocrine gland plays an equal 1. Which of the following statements part. about homeostasis are false? C They produce a model of several phases. A It is defined as a stable state of the D The phases occur over several days. normal body. E They help in the process of repair. B The central nervous system, heart, lungs, ➜ kidneys and spleen are the essential The recovery process organs that maintain homeostasis at a 4. With regard to the recovery process, normal level. identify the statements that are true. C Elective surgery should cause little A All tissues are catabolic, resulting in repair disturbance to homeostasis. at an equal pace. D Emergency surgery should cause little B Catabolism results in muscle wasting. disturbance to homeostasis. C There is alteration in muscle protein E Return to normal homeostasis after breakdown. an operation would depend upon the D Hyperalimentation helps in recovery. presence of co-morbid conditions. E There is insulin resistance. ➜ Stress response ➜ Optimal perioperative care 2. In stress response, which of the 5. Which of the following statements are following statements are false? true for optimal perioperative care? A It is graded. A Volume loss should be promptly treated B Metabolism and nitrogen excretion are by large intravenous (IV) infusions of related to the degree of stress. fluid. C In such a situation there are B Hypothermia and pain are to be avoided. physiological, metabolic and C Starvation needs to be combated. immunological changes. D Avoid immobility. D The changes cannot be modified. -
Yagenich L.V., Kirillova I.I., Siritsa Ye.A. Latin and Main Principals Of
Yagenich L.V., Kirillova I.I., Siritsa Ye.A. Latin and main principals of anatomical, pharmaceutical and clinical terminology (Student's book) Simferopol, 2017 Contents No. Topics Page 1. UNIT I. Latin language history. Phonetics. Alphabet. Vowels and consonants classification. Diphthongs. Digraphs. Letter combinations. 4-13 Syllable shortness and longitude. Stress rules. 2. UNIT II. Grammatical noun categories, declension characteristics, noun 14-25 dictionary forms, determination of the noun stems, nominative and genitive cases and their significance in terms formation. I-st noun declension. 3. UNIT III. Adjectives and its grammatical categories. Classes of adjectives. Adjective entries in dictionaries. Adjectives of the I-st group. Gender 26-36 endings, stem-determining. 4. UNIT IV. Adjectives of the 2-nd group. Morphological characteristics of two- and multi-word anatomical terms. Syntax of two- and multi-word 37-49 anatomical terms. Nouns of the 2nd declension 5. UNIT V. General characteristic of the nouns of the 3rd declension. Parisyllabic and imparisyllabic nouns. Types of stems of the nouns of the 50-58 3rd declension and their peculiarities. 3rd declension nouns in combination with agreed and non-agreed attributes 6. UNIT VI. Peculiarities of 3rd declension nouns of masculine, feminine and neuter genders. Muscle names referring to their functions. Exceptions to the 59-71 gender rule of 3rd declension nouns for all three genders 7. UNIT VII. 1st, 2nd and 3rd declension nouns in combination with II class adjectives. Present Participle and its declension. Anatomical terms 72-81 consisting of nouns and participles 8. UNIT VIII. Nouns of the 4th and 5th declensions and their combination with 82-89 adjectives 9. -
Radiological Localization of Greater Palatine Foramen Using Multiple Anatomical Landmarks
MOJ Anatomy & Physiology Research Article Open Access Radiological localization of greater palatine foramen using multiple anatomical landmarks Abstract Volume 2 Issue 7 - 2016 Identification of greater palatine foramen is of prime value for dentists and the oral and Viveka S,1 Mohan Kumar2 maxillofacial surgeons. The objective of present study was to radiologically localize greater 1Department of Anatomy, Azeezia Institute of Medical Sciences, palatine foramen with multiple anatomical landmarks. All Computer Tomography scans India of individuals who have undergone paranasal sinus evaluation were obtained from the 2Department of Radiology, Azeezia Institute of Medical Sciences, Department of Radiology, Azeezia Institute of Medical Sciences, from April 2015 to April India 2016. Distance of greater palatine foramen from various known anatomical landmarks was measured across the CT slices. Forty-four CT scans were studied, mean age was 32(±2.3) Correspondence: Viveka S, Assistant professor, Department years. All scans were from individuals of south Indian origin. GPF was located at 38.38mm of Anatomy, Azeezia Institute of Medical Sciences, Kollam, India, from incisive fossa, 17.6mm from posterior nasal spine, 18.38mm from intermaxillary Email [email protected] suture, 5.03mm from second molar and 5.28mm from third molar. Distances of GPF from incisive foramen and intermaxillary suture differed significantly on right and left sides. In Received: May 25, 2016 | Published: December 29, 2016 25(56.8%) cases GPF was located closer to third molar. In seven cases, it was closer to second molar and in 12 cases, GPF was located at the junction of second and third molar. Posterior location of GPF, posterior to third molar is not noted. -
Hard Palate, Intermaxillary Sulcus, Greater Palatine Foramen, Lesser Palatine Foramen
Basic Sciences of Medicine 2020, 9(3): 44-45 DOI: 10.5923/j.medicine.20200903.02 Twin Foramina in Posterior Third of an Adult Hard Palate and Their Significance Rajani Singh Department of Anatomy, UP University of Medical Sciences, Saifai Etawah, India Abstract Hard palate is formed by union of maxillary process of palatine bone and horizontal plate of palatine bone during development of foetus in 12th week. Three types of foramina, greater palatine allowing greater palatine nerves and vessels, lesser palatine and incisive foramina allowing passage of lesser palatine and nasopalatine nerves respectively are normally present in hard palate. The purpose of study is to report two novel foramina in hard palate and to bring out associated clinical significance. The author observed two new foramina one on either side of intermaxillary sulcus at the junction of anterior 2/3rd and posterior 1/3rd of hard palate during scanning of base of skulls for any abnormality in the Department of Anatomy of my native institute. The diameters of the right sided foramen was 6 mm while that of on left sided was 5 mm. The distance of foramen from midline on the right side was 3 mm while that of on left side was 2 mm. The distance of foramen on the right side from the centre of inferior border of hard palate was 13 mm while that of left side was 10 mm. The hard palate separates nasal cavity and oral cavity and essential for speech, feeding and respiration. The anomalous foramina observed may create problems during speech, feeding and respiration.