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Plants and Laboratory

Noto Plant Shiga Product Supply Center Tampere Plant 2-14, Shikinami, Houdatsushimizu-cho, 348-3, Aza-suwa, Oaza-shide, Taga-cho, Niittyhaankatu 20, P.O. Box 33, Hakui-gun, Ishikawa 929-1494, Japan Inukami-gun, Shiga 522-0314, Japan FIN-33721 Tampere, TEL: +81-767-29-2666 FAX: +81-767-29-4233 TEL: +81-749-48-2900 FAX: +81-749-48-2901 TEL: +358-3-284-8111 FAX: +358-3-318-1900

Suzhou Plant Nara Research and Development Center No. 169 Tinglan Road, Suzhou Industrial Park, 8916-16, Takayama-cho, Ikoma-shi, Nara Jiangsu Province 215026, P.R.C. 630-0101, Japan TEL: +86-512-6295-7500 FAX: +86-512-6295-7800 TEL: +81-743-79-4501 FAX: +81-743-79-4521

78 Santen Pharmaceutical Co., Ltd. Annual Report 2013 Business Bases 79 Annual Report 2013 Production, marketing, clinical Production, development of pharmaceuticals Development, production, Development, production, marketing of medical devices Centralization of financial controls operations for European Business development, planning, product marketing of pharmaceuticals Marketing of pharmaceuticals Pharmaceutical market research Clinical development of pharmaceuticals and business development development, production, Research, marketing of pharmaceuticals development, Research, marketing of pharmaceuticals and medical devices Marketing support of pharmaceuticals Marketing, clinical development of pharmaceuticals Research, development, production, development, production, Research, and marketing of pharmaceuticals medical devices Cleaning of antidust and sterilized clothing Holding company for and North American businesses business development Business Santen Pharmaceutical Co., Ltd. +82-2-754-2929 : FAX: +886-2-2700-1730 FAX: +91-80-4932-3799 FAX: FAX: +33-1-69-87-40-30 FAX:

FAX: +1-805-964-3065 FAX: FAX: +358-3-318-1900 FAX: FAX: +81-749-48-2239 FAX: FAX: +49-89-848078-60 FAX: FAX: +1-510-655-5682 FAX: +82-2-754-1434 FAX : 5743 Thornwood Drive, Goleta, California 93117, U.S.A. TEL: +1-805-683-3851 Herikerbergweg 238, Zuidoost, 1101CM Amsterdam Fontaine, Genavenir IV, 1 rue Pierre F-91058 Evry cedex, TEL: +33-1-69-87-40-20 Niittyhaankatu 20, P.O. Box 33, Niittyhaankatu 20, P.O. Finland FIN-33721 Tampere, TEL: +358-3-284-8111 3F C&K Tower, 35, Yeoksam-ro 25-gil, Gangnam-gu, 35, Yeoksam-ro 3F C&K Tower, Seoul, 135-921, Korea TEL R.O.C. South Rd., Taipei, No. 57, Sec. 2, Tun-Hwa 16F, TEL: +886-2-2700-1553 No. 216, Raheja Chambers, 12 Museum Road, 560 001, Bangalore TEL: +91-80-4932-3700 Erika-Mann-Strasse 21 80636 Munchen, TEL: +49-89-848078-0 Solna torg 3, SE-17145 Solna, +46-8-83-4145 TEL: +46-8-83-4140 FAX: 169 Tinglan Road, Suzhou Industrial Park, No. 215026, P.R.C. Jiangsu Province +86-512-6295-7800 TEL: +86-512-6295-7500 FAX: 2100 Powell Street, Suite 1600, Emeryville, 2100 Powell Street, California 94608, U.S.A. TEL: +1-415-268-9100 Grand Front Osaka Tower A, Osaka Tower Grand Front 530-8552, Japan 4-20 Ofuka-cho, Kita-ku, Osaka 25th Floor.) (Reception desk is on the +81-6-6328-5082 TEL: +81-6-6321-7000 FAX: 348-3, Aza-suwa, Oaza-shide, Taga-cho, Inukami-gun, Inukami-gun, Taga-cho, 348-3, Aza-suwa, Oaza-shide, Shiga 522-0314, Japan TEL: +81-749-48-2234 2100 Powell Street, Suite 1600, Emeryville, Suite 1600, Emeryville, 2100 Powell Street, CaliforniaU.S.A. 94608, Suit 1206B, TOWER W3, Oriental Plaza, No. 1, Dong Cheng District, Beijing 100738, P.R.C. East Chang An Ave., +86-10-8515-1020 TEL: +86-10-8515-1515 FAX: Santen Holdings U.S. Inc. Santen Holdings U.S. Beijing Representative Office Beijing Representative Santen Pharmaceutical Co., Ltd. Taiwan Santen India Private Limited Santen Pharmaceutical () Co., Ltd. Co., Ltd. Santen Pharmaceutical Korea Santen GmbH SantenPharma AB Santen Holdings EU B.V. Santen Oy Santen S.A.S. Advanced Vision Science, Inc. Advanced Vision Santen Inc. Claire Co., Ltd Claire Corporate Headquarters Other Office Corporate Headquarters and Subsidiaries Headquarters Corporate