GPR112 (ADGRG4) (NM 153834) Human Untagged Clone Product Data

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for SC306666

GPR112 (ADGRG4) (NM_153834) Human Untagged Clone Product data:

Product Type: Expression Plasmids Product Name: GPR112 (ADGRG4) (NM_153834) Human Untagged Clone Tag: Tag Free Symbol: ADGRG4 Synonyms: GPR112; PGR17; RP1-299I16 Vector: pCMV6-XL5 E. coli Selection: Ampicillin (100 ug/mL) Cell Selection: None Fully Sequenced ORF: >OriGene sequence for NM_153834 edited ATGAAAGAACACATCATATATCAGAAGCTTTATGGATTGATTCTCATGTCGAGTTTTATC TTTCTCTCAGATACACTTTCACTAAAAGGAAAAAAGCTGGATTTTTTTGGAAGAGGTGAC ACATATGTAAGCCTGATAGATACCATTCCTGAACTCAGCCGATTCACAGCATGCATTGAT CTGGTATTCATGGATGACAACTCAAGGTATTGGATGGCCTTCTCTTATATTACTAATAAC GCCCTCCTGGGCAGAGAAGACATAGACCTTGGACTTGCAGGAGACCATCAGCAGCTAATA CTATACAGATTGGGAAAGACCTTTTCTATCCGTCACCACCTGGCTTCATTTCAATGGCAT ACAATATGCTTGATATGGGATGGTGTGAAGGGCAAATTAGAACTCTTCCTGAATAAAGAA AGGATACTGGAAGTAACGGATCAACCACACAACCTGACACCTCATGGGACTCTGTTCCTA GGGCACTTTCTCAAGAATGAGAGCAGCGAGGTTAAAAGCATGATGCGTAGCTTTCCTGGC AGCTTGTACTACTTTCAACTCTGGGACCACATCCTGGAAAACGAAGAGTTTATGAAGTGT TTAGATGGAAATATAGTTAGTTGGGAAGAAGACGTCTGGCTTGTCAACAAGATCATCCCA ACTGTTGACAGGACACTGCGCTGCTTTGTTCCTGAAAATATGACAATTCAAGAAAAAAGT ACAACTGTTTCACAACAGATAGATATGACCACTCCATCCCAAATTACTGGAGTAAAACCA CAAAATACTGCACATTCCTCTACACTATTGTCTCAAAGCATACCTATATTTGCAACTGAT TACACAACCATATCATATTCCAATACAACATCTCCACCTCTGGAAACAATGACTGCACAA AAAATCTTAAAGACACTGGTAGATGAGACAGCTACATTTGCAGTGGATGTTTTATCAACT TCATCAGCCATCTCTCTGCCTACCCAGAGTATATCCATAGACAATACTACCAATTCCATG AAAAAAACGAAATCTCCATCTTCAGAAAGCACAAAGACAACAAAAATGGTTGAAGCCATG GCTACTGAAATCTTTCAACCACCTACACCTTCTAATTTCCTATCCACATCCAGATTTACC AAGAATTCAGTTGTATCTACAACTTCAGCAATTAAATCTCAGTCGGCTGTTACGAAGACA ACATCTTTATTTTCAACTATTGAGTCAACATCTATGTCTACAACACCTTGTCTCAAACAA AAATCCACAAATACTGGGGCACTCCCTATCTCCACAGCTGGCCAGGAGTTCATTGAATCT ACAGCTGCCGGAACTGTACCTTGGTTTACAGTGGAAAAGACTTCACCTGCATCTACTCAT GTTGGGACTGCATCATCATTCCCACCTGAGCCTGTGCTCATCTCCACAGCTGCTCCAGTA GATTCTGTATTTCCTAGAAACCAGACAGCATTTCCATTGGCAACAACTGATATGAAAATA GCATTTACAGTCCATTCATTGACTCTCCCAACTAGGCTTATTGAGACCACACCTGCCCCA AGGACAGCTGAAACAGAATTGACATCTACAAATTTTCAGGATGTCTCTTTACCCAGAGTG

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 5 GPR112 (ADGRG4) (NM_153834) Human Untagged Clone – SC306666

GAAGATGCCATGTCTACTTCCATGTCGAAAGAGACCTCCTCTAAGACCTTTTCTTTCTTA ACATCCTTTTCATTTACTGGGACTGAGAGTGTACAGACAGTTATTGATGCTGAAGCTACA CGTACAGCCTTAACTCCTGAAATCACACTTGCATCTACAGTGGCTGAAACTATGCTTTCC TCCACAATCACAGGACGAGTTTACACCCAGAATACACCTACAGCTGATGGACACTTGCTT ACTTTGATGTCCACTAGATCAGCTTCCACATCCAAGGCACCTGAGTCAGGTCCCACATCC ACAACTGATGAAGCTGCCCATCTGTTCTCCAGCAATGAGACCATTTGGACTTCTAGGCCA GACCAGGCCCTGCTGGCATCTATGAACACAACCACCATACTCACATTTGTGCCTAATGAA AATTTTACATCAGCATTTCATGAGAATACTACTTATACAGAATATTTATCCGCAACTACC AATATCACCCCACTGAAAGCATCTCCAGAGGGCAAAGGTACCACTGCCAATGATGCTACT ACAGCCAGATATACAACAGCTGTATCCAAATTGACATCACCATGGTTTGCTAATTTCTCC ATAGTTTCTGGAACCACATCCATAACCAATATGCCTGAATTTAAACTTACCACTTTACTA CTAAAAACAATACCTATGTCTACAAAACCTGCAAATGAACTTCCTTTGACACCAAGGGAG ACTGTTGTTCCATCAGTAGATATAATATCTACTCTTGCTTGCATTCAACCAAATTTTTCT ACTGAGGAAAGTGCTTCTGAGACCACACAAACAGAAATAAATGGTGCAATTGTATTTGGA GGTACAACGACCCCTGTACCAAAGTCAGCAACAACACAAAGATTAAATGCCACTGTGACA AGAAAAGAAGCAACTTCCCATTATCTTATGAGAAAATCAACTATAGCAGCAGTGGCTGAG GTTTCTCCATTTTCAACAATGCTGGAAGTGACAGACGAATCAGCACAAAGGGTGACAGCT TCTGTCACTGTTTCCTCTTTTCCTGATATAGAAAAGCTAAGTACCCCATTGGATAATAAA ACTGCAACAACTGAGGTGAGAGAAAGTTGGCTTTTGACAAAATTGGTGAAAACCACACCT AGGAGTTCATACAATGAAATGACAGAAATGTTTAATTTTAACCACACCTATGTAGCACAT TGGACTTCAGAGACATCTGAGGGAATTTCAGCTGGATCTCCCACTTCTGGGAGCACACAT ATATTCGGTGAACCCCTGGGTGCTTCTACCACAAGGATATCAGAAACCAGTTTCTCCACT ACCCCTACAGACAGGACAGCTACGTCCTTGTCTGATGGTATCTTACCTCCACAGCCTACA GCTGCTCATTCCTCAGCAACCCCTGTGCCTGTTACTCATATGTTCTCATTGCCAGTTAAT GGCAGTTCTGTGGTGGCTGAGGAGACTGAGGTTACCATGTCTGAGCCTTCTACACTGGCC AGGGCTTTTTCTACATCTGTGCTCTCAGATGTCTCAAATCTATCCTCAACTACAATGACC ACAGCATTGGTACCACCTTTGGATCAGACTGCTTCCACAACCATTGTTATTGTGCCTACC CATGGAGACTTGATTCGTACCACTTCAGAGGCCACGGTAATCTCTGTCAGGAAGACATCC ATGGCAGTTCCTTCTCTGACAGAAACACCATTTCATTCACTGAGACTCTCCACTCCTGTG ACAGCTAAGGCTGAGACCACCCTTTTCTCTACCTCAGTTGATACAGTAACCCCATCTACA CACACTCTTGTCTGCTCAAAACCTCCCCCTGACAACATTCCTCCTGCGTCCTCCACTCAT GTGATCTCAACTACGTCTACACCAGAAGCAACTCAACCAATATCTCAAGTAGAGGAGACT TCTACCTATGCTCTCAGCTTCCCATATACTTTCAGTGGTGGTGGAGTTGTTGCCAGCTTG GCTACTGGCACCACAGAGACCTCTGTTGTTGATGAGACCACACCCTCACACATCTCTGCC AATAAGTTGACTACTTCAGTAAACAGTCACATTTCTTCATCTGCCACATATCGTGTACAC ACACCAGTGTCCATCCAGTTGGTGACTAGCACCTCTGTCTTATCTTCCGACAAAGACCAG ATGACCATATCCCTGGGAAAAACCCCTAGAACTATGGAGGTGACAGAAATGTCCCCATCA AAGAATTCTTTTATTTCATACTCCCGGGGTACTCCATCTTTGGAAATGACAGATACAGGA TTTCCTGAGACCACAAAAATTTCCAGTCACCAAACACATTCGCCTTCAGAGATTCCACTT GGGACTCCCTCTGATGGAAATTTGGCTTCATCTCCCACTTCTGGAAGCACACAGATTACA CCAACCTTGACCTCAAGTAACACAGTAGGTGTTCACATTCCAGAAATGTCTACCAGTCTT GGGAAAACAGCTCTCCCCTCACAAGCTCTGACAATCACCACTTTTTTGTGTCCTGAAAAG GAAAGCACGAGTGCCCTTCCAGCATATACTCCCAGGACTGTGGAAATGATAGTAAACTCC ACCTATGTGACTCACTCTGTCTCATATGGCCAGGATACTTCATTTGTAGATACCACAACT TCCAGCTCAACAAGGATATCAAATCCTATGGACATCAATACAACTTTTTCACACTTGCAT TCACTTAGGACACAACCTGAGGTGACTTCAGTTGCCTCTTTCATTTCTGAAAGCACACAG ACTTTCCCTGAGTCCTTGTCTCTTTCCACAGCTGGACTATATAATGACGGTTTTACAGTT CTCTCCGACAGGATCACTACAGCCTTTTCTGTTCCAAATGTACCTACAATGCTTCCTAGA GAATCCTCTATGGCAACGTCCACTCCTATTTACCAGATGTCCTCATTGCCAGTTAATGTA ACTGCCTTCACCTCCAAAAAAGTTTCTGACACTCCCCCAATAGTGATAACTAAATCTTCT AAAACAATGCATCCAGGTTGTTTGAAAAGTCCCTGTACAGCCACTTCTGGGCCTATGTCT GAGATGTCCTCAATACCAGTTAATAACTCTGCTTTCACACCTGCAACAGTCTCTTCTGAC

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 5 GPR112 (ADGRG4) (NM_153834) Human Untagged Clone – SC306666

ACTTCCACAAGAGTTGGGTTATTCTCTACTTTATTGTCTTCAGTTACCCCCAGGACTACT ATGACCATGCAAACATCTACATTGGATGTCACACCTGTGATATATGCTGGGGCTACTTCA AAAAACAAAATGGTTTCCTCTGCTTTCACTACAGAAATGATAGAGGCACCTTCCAGGATC ACACCTACGACCTTTCTCTCTCCAACAGAGCCAACTTTGCCCTTTGTAAAAACCGTTCCC ACCACCATTATGGCTGGGATAGTGACTCCATTTGTAGGCACCACTGCCTTCTCTCCACTC AGTTCTAAGAGCACTGGAGCTATTTCCTCCATTCCAAAGACCACATTTTCACCATTTCTA TCAGCAACTCAACAGTCATCACAAGCAGATGAGGCTACAACTTTGGGCATATTATCTGGG ATTACTAACAGGTCCCTATCTACTGTGAACAGTGGTACAGGGGTAGCTCTCACAGATACT TATTCCAGAATCACTGTTCCTGAAAATATGCTTTCACCTACTCATGCAGATAGTCTCCAT ACTTCCTTCAATATTCAGGTTTCCCCATCTCTGACTAGCTTTAAGAGTGCTTCTGGACCC ACAAAAAATGTTAAAACAACCACCAATTGCTTTTCTTCTAATACTAGAAAGATGACTTCC TTGTTAGAAAAGACTTCCTTAACAAACTATGCCACATCTTTGAATACCCCTGTTTCATAC CCTCCATGGACCCCATCCAGTGCAACTCTACCCTCTTTGACATCATTTGTTTATTCACCT CATAGTACTGAAGCTGAGATCTCTACTCCAAAGACCTCTCCTCCTCCCACATCCCAAATG GTTGAATTTCCAGTTCTGGGAACAAGAATGACATCTAGTAATACCCAACCTCTGCTTATG ACTTCCTGGAACATACCCACAGCTGAAGGTTCTCAGTTTCCAATTTCCACCACTATTAAT GTACCTACATCCAATGAGATGGAAACAGAGACTCTACACCTTGTTCCTGGGCCTTTGTCA ACATTCACAGCCTCTCAGACTGGTCTAGTATCTAAAGATGTCATGGCAATGTCATCAATT CCTATGTCAGGAATTCTTCCTAACCATGGGCTTTCTGAGAACCCTTCATTATCAACATCT TTAAGAGCTATCACTTCCACATTGGCTGACGTTAAGCACACATTTGAGAAAATGACCACA TCTGTAACTCCTGGGACCACACTCCCATCAATTCTTTCTGGTGCCACTTCAGGATCTGTA ATTTCAAAGTCACCCATTCTGACATGGCTCTTATCTAGTCTCCCTTCTGGCTCCCCTCCG GCAACTGTATCTAATGCCCCTCATGTTATGACTTCCTCTACAGTAGAGGTGTCAAAATCA ACATTTCTGACATCTGACATGATATCAGCGCACCCATTCACTAACTTGACAACACTACCC TCTGCTACTATGAGCACCATACTCACCCGAACCATTCCTACACCTACACTGGGTGGTATC ACTACTGGCTTCCCAACTTCTCTCCCTATGTCTATAAATGTCACAGATGACATTGTGTAC ATTTCCACACACCCTGAGGCATCCTCCAGAACCACAATAACTGCCAACCCCAGGACTGTG TCTCATCCTTCATCCTTCAGCAGAAAGACTATGTCACCTTCTACAACTGACCACACTCTA TCTGTTGGTGCCATGCCTCTGCCTAGCTCTACAATAACATCTTCATGGAACAGAATTCCA ACTGCATCATCACCCTCTACTTTAATTATTCCTAAGCCCACACTGGACTCCCTTCTAAAT ATAATGACTACTACATCCACTGTTCCTGGAGCCTCATTTCCACTCATATCCACTGGGGTG ACATATCCTTTTACAGCAACTGTGTCTTCACCAATATCGTCCTTTTTTGAAACAACTTGG CTGGACTCCACACCTTCCTTTCTATCTACGGAAGCATCGACTTCGCCTACTGCCACCAAG TCCACAGTTTCCTTCTACAATGTTGAAATGAGCTTCTCTGTCTTTGTTGAAGAGCCAAGG ATCCCTATTACCAGTGTTATAAATGAATTTACGGAAAATTCGTTGAATTCTATATTTCAG AACAGTGAATTTTCTCTTGCTACTCTGGAAACCCAAATTAAAAGCAGGGACATTTCAGAG GAAGAGATGGTCATGGATCGAGCTATTTTGGAACAGAGAGAAGGACAAGAAATGGCTACA ATTTCCTATGTACCATACAGTTGTGTTTGTCAGGTCATCATAAAAGCCAGCTCTTCCTTA GCATCCTCTGAATTGATGAGAAAAATCAAAAGTAAAATACATGGCAACTTCACACATGGA AACTTCACACAAGATCAATTGACGTTATTAGTAAACTGTGAACACGTTGCAGTGAAAAAA CTAGAGCCTGGAAATTGCAAAGCTGATGAAACAGCCTCTAAATACAAAGGGACCTATAAG TGGCTATTAACCAACCCTACGGAGACAGCCCAAACCAGATGCATAAAAAATGAGGATGGA AATGCCACAAGATTCTGTTCAATCAGCATCAACACGGGCAAATCTCAGTGGGAAAAGCCA AAGTTTAAACAATGCAAATTGCTTCAAGAACTTCCTGACAAGATTGTGGATCTTGCTAAT ATTACCATAAGTGATGAGAATGCTGAGGATGTTGCAGAGCATATTTTAAATTTGATAAAT GAATCCCCAGCCCTGGGTAAAGAAGAGACAAAGATTATTGTTTCTAAAATATCAGATATT TCACAATGTGATGAGATAAGTATGAACCTAACTCATGTTATGTTACAAATAATCAACGTT GTTTTGGAAAAGCAAAACAATTCCGCCTCTGATCTGCATGAAATAAGCAATGAAATTCTG AGGATAATTGAGCGTACTGGTCACAAGATGGAGTTTTCTGGGCAGATAGCAAATCTGACG GTGGCCGGGCTGGCTTTGGCTGTGCTGCGGGGGGACCACACGTTTGATGGCATGGCTTTC AGCATTCACTCCTATGAAGAAGGCACAGACCCTGAGATTTTCCTAGGCAATGTCCCTGTG GGAGGGATTTTGGCTTCCATATATTTGCCTAAATCACTGACGGAGAGAATTCCTCTTAGC

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 3 / 5 GPR112 (ADGRG4) (NM_153834) Human Untagged Clone – SC306666

AACTTACAAACGATCTTGTTTAATTTCTTTGGCCAAACTTCACTCTTTAAGACCAAAAAT GTCACTAAAGCATTAACCACCTATGTTGTGAGTGCCAGCATTTCAGATGATATGTTCATT CAAAACTTAGCTGACCCAGTGGTTATCACTCTGCAGCATATTGGAGGAAACCAGAATTAT GGTCAAGTTCACTGTGCCTTTTGGGATTTTGAGAATAATAATGGGCTGGGTGGATGGAAT TCGTCAGGCTGTAAAGTAAAGGAAACAAATGTAAATTACACAATCTGTCAGTGTGACCAC CTCACCCATTTTGGAGTCTTAATGGATTTATCCAGGTCTACAGTGGATTCAGTGAATGAA CAGATATTAGCGCTTATAACATACACCGGATGTGGAATCTCCTCCATTTTTCTGGGAGTT GCAGTGGTGACATACATAGCTTTTCACAAACTTCGAAAAGATTATCCTGCCAAAATTCTG ATCAACCTGTGCACAGCACTACTGATGCTAAACCTGGTATTTTTGATCAATTCTTGGTTG TCATCATTTCAGAAAGTGGGAGTTTGTATCACAGCTGCAGTGGCACTTCATTACTTCCTG CTTGTTTCTTTTACTTGGATGGGCCTGGAGGCAGTCCACATGTATTTGGCTCTAGTCAAA GTCTTCAACATATACATTCCAAATTATATCCTTAAATTTTGTCTAGTTGGTTGGGGAATC CCGGCTATCATGGTGGCAATCACAGTCAGTGTGAAAAAAGATCTGTATGGAACTCTGAGC CCAACAACTCCGTTTTGTTGGATTAAAGATGATTCTATCTTTTACATCTCAGTGGTGGCT TATTTTTGCCTCATATTTCTCATGAATCTCTCCATGTTCTGCACTGTTCTTGTTCAACTG AATTCTGTGAAATCCCAAATCCAGAAGACTCGGCGGAAGATGATCCTGCATGACCTCAAA GGCACAATGAGCCTGACATTCTTACTTGGCCTCACCTGGGGGTTTGCATTTTTTGCTTGG GGACCCATGAGGAACTTTTTCTTGTATTTGTTTGCCATTTTTAACACTTTGCAAGGATTC TTCATTTTTGTGTTTCACTGTGTGATGAAGGAGAGTGTGCGGGAGCAGTGGCAGATACAC CTCTGCTGTGGGTGGTTGCGATTGGATAACTCTTCTGATGGGAGCAGCCGGTGTCAGATA AAGGTTGGATATAAACAGGAGGGACTAAAGAAAATCTTTGAGCACAAACTGTTGACGCCA TCTCTCAAGTCAACTGCAACTAGCTCCACTTTCAAATCTTTAGGCTCTGCACAAGGCACA CCTTCAGAAATAAGCTTTCCAAATGATGACTTTGACAAAGATCCTTACTGTTCCTCTCCT TGA Restriction Sites: Please inquire ACCN: NM_153834 Insert Size: 9200 bp OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at [email protected] or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. RefSeq: NM_153834.3, NP_722576.3 RefSeq Size: 9931 bp RefSeq ORF: 9243 bp

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 4 / 5 GPR112 (ADGRG4) (NM_153834) Human Untagged Clone – SC306666

Locus ID: 139378 UniProt ID: Q8IZF6

Protein Families: Druggable Genome, Transmembrane Gene Summary: This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010]