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Editor’s Note Issue No. 2 May – August, 2015

Scientific Program : 26th Annual Conference AGE of Indian Society of , Gujarat University Of Transplantation Sciences (GUTS)

ON P 2 2 - 4 October 2015, Dear colleagues and friends Greetings from Lucknow. Hope you Gets The First had received the first issue of ISOT Newsletter in time and liked its content and the production standards. Shall Transplant Varsity Of World look forward to your The long cherished dream of Prof. H.L. Trivedi, was at last realized suggestions and ideas as to how we in May, 2015 with the creation of a University of Transplantation can make it more Sciences at Ahmedabad which happens to be the World’s first. worthy, content and communication wise. The Notification to the effect was issued GUTS would be a non-affiliating I am thankful to all of by Department of Health and Family University and will have its constituent, you in making this Welfare, Government of Gujarat, on recognized or approved colleges or effort of mine, a grand success. 29th April, 2015 and “Gujarat University schools in future. Of Transplantation Sciences” (GUTS) The second issue of ISOT Newsletter is The mission of the University is to serve started functioning from 1st May, now in your hands covering some as an academic and research '15 with Prof. H. L. Trivedi the important scientific articles and nucleus to these specialties to founder – Director of IKDRC-ITS, happenings and news of Indian improve the clinical, scientific, and transplant world, in its own humble as its first Pro-Chancellor and social aspects of Transplantation way. Prof. Veena R. Shah, the Deputy m a k i n g i t a c c e s s i b l e a n d Director and HOD Anesthesia and On page 2 onwards you will find affordable to population at large giving th Critical Care of IKDRC-ITS, as its first Scientific Program of 26 Annual them healthy and productive lives. Conference of Indian Society of Organ Vice Chancellor. Different specialty, super-specialty and Transplantation, to be held on 2 - 4 Prof. Kamal V. Kanodia, Prof. of Dept. of paramedical courses will begin from October 2015 at Chennai. The details of Nominations / Applications for Pathology, Lab Medicine, Transfusion this academic year. Services and Immunohematology of ISOT Oration Awards and The website www.guts.education has IKDRC-ITS, was appointed its first Fellowship, are also given on also been launched. g Send in Registrar. Your News, ..... page. You are requested to submit your applications for the Views & same by 25th August 2015. Reviews Your feedback is important in addressing the various issues faced by the transplant community at large and the Indian Society of Organ Transplantation in particular. Sincerely yours, Narayan Prasad Designed and printed by Alpana Productions, Lucknow on behalf of its Editor, Prof Narayan Prasad, Secretary, Indian Society of Organ Transplantation (ISOT), Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rae Bareli Road, Lucknow, 226 014 UP, . 2 ISOT Newsletter May to August 2015 May to August 2015 ISOT Newsletter 3

Plenary & Renal Scientific Programme 26TH ANNUAL CONFERENCE OF Dear Delegates, Who Should Attend INDIAN SOCIETY OF Greetings from the Organizing Committee of the 26th Annual Conference of The congress will have sessions related to kidneys, , , nd ORGAN TRANSPLANTATION , hand, donation and transplantation. It aims to brings 2 October 2015 Indian Society of Organ Transplantation. It is our proud privilege to make the first together - Transplant Physicians, Transplant Surgeons, announcement of this Conference and welcome you to Chennai. Transplant Scientists, Transplant Pathologists, Transplant Time Topic Immunologists, Transplant Coordinators & Nurses and Other 08:00-09:00 Registration The venue and dates for the conference have been finalized. Chennai is hosting transplant professionals this conference after 17 years and many, who attended the last conference, will Histo-Compatiblity Testing for the clinician - 20 mins Workshops On Chennai remember it with some fond memories. Do check out the website to see images JM Patel Oration - 30 mins 2nd to 4th October 2015 Interventional Nephrology from the 1997 conference and take a walk down memory lane. Antibody mediated allo-immune responses - 30 mins Transplant Coordinators The current organizing committee will try and match the hospitality of the 1997 Surrogacy in immune surveillance - 20 mins Transplant Immunology conference and ensure that the scientific content of the meeting is of the highest 08:30-11:00 Symposium on ABO incompatible Transplantation quality. The committee will do its very best to bring together leading national and Transplant Pathology - 50 mins international faculty for the conference. Our endeavor will be to ensure that the Abstract Online: http://www.isot2015.com/abstract.asp l Basic Science - 11 mins delegates get the best value of their time and money. Making this conference a Registration Online: http://www.isot2015.com/register.asp l Heart and – 13 mins memorable experience is one of the highest priorities of the organizing l Liver – 13 mins Registered delegates will enjoy all the benefits of the conference, committee. l – 13 mins however this cannot be guaranteed for spot registration. Chennai is the gateway for exploring 'South India' and there are many interesting Delegates will receive a comprehensive 'Conference Kit' along 11:00-11:20 Tea / Coffee Break and historical places to visit. Please plan your visit well in advance to enjoy your with other benefits such as lunch, dinner and beverages. Concurrent session LIVER, HAND, PATHO and TID stay in this part of the world. Registrations also get a free entry to the 'Trade Fair' organized to Late Kidney Allograft failure (55 mins) Dr. Georgi Abraham Dr. Sunil Shroff display the latest products from the Pharma Companies. Please remember that 'Early Bird' enjoy discounted registration. Immunology perspectives - 15 mins Secretariat for ISOT 2015 Conference Pathological perspectives - 15 mins Yours truly, MOHAN Foundation, 3rd Floor, 267 Kilpauk Garden Road, 11:20-12:15 Chennai 600010, India Tel +91-44-26447000/+919444607000 Nephrology perspectives - 15 mins Dr. Sunil Shroff Dr. Georgi Abraham Email: [email protected]/[email protected] Discussion - 10 mins Organizing Secretary Organizing Chairman Desensitization Coming of Age - 20 mins Handling patients with positive cross-match 12:15-13:00 in Indian context Overview of Scientific Program Proposed Pre Conference Workshop Discussion - 5 mins 13:00-13:45 Lunch Break Day 1 Day 2 Day 3 st Symposium - 75 mins Time nd rd th 1 October 2015 2 October 2015 3 October 2015 4 October 2015 Urinary Tract Infections Post Transplant Time Topic UTI in diabetic renal transplant - 15 mins 07:00 Instruction Course Instruction Course Pediatric Transplantation - 15 mins each 13:45-15:00 BKV - 15 mins 08:00 Registration Registration Registration l The Future of Immunosuppressive Therapy in Genomics - 15 mins Children after SOT 08:30-11:00 Plenary Session Plenary Session Plenary Session 14:00-15:00 l Pediatric Isurgical cause of UTI - 15 mins Coffee Break Coffee Break Coffee Break l Surgical challenges in Pediatric Transplantation Resistant MDR bugs - 15 mins l Application of novel biomarkers in pediatric transplant Difficult Case scenarios- Nephro - Concurrent Sessions Concurrent Sessions Concurrent Sessions Immunology Perspectives - 15 mins each 15:00-16:00 Uro Related to Transplant - 30 mins (6 cases each 10 mins) l Influence of Ischemia Reperfusion Injury on immune l Kidney l Kidney l Kidney · system: 16:00-16:15 Transplantation in abnormal bladder - 15 mins 11:15-16:00 l l Liver, and small Liver, Pancreas and small l l Non-complement Fixing and Non-HLA Antibodies in 45 minutes Critical care and anaesthesia 15:00-16:00 PLENARY EVENING bowel bowel kidney transplantation Lunch Break l Paper Presentations Making Renal Transplantation Affordable - 20 mins within l Heart and Lung l Heart and Lung l Immunologic Issues in Deceased Donor l Transplant Coordination session l Infections In Transplant l Infections In Transplant Transplantation RVS Yadav Oration - 25 mins l Evolution of the Clinical Application of Stem Cells Donation after cardiac - 20 mins l Immunology and pathology l Transplant Coordination 16:15-18:00 16:00-16:15 Tea / Coffee Break Organ Preservation and Perfusion : l Reconstructive Transplant Post transplant problems orientation - 15 mins each In the cold light of day ice is king - 20 mins Coffee Break Coffee Break Coffee Break l Post transplant diarrhoea Are we ready to come in from the cold? - 20 mins 16:15-17:15 l Vaccination in solid organ transplant recipient 18:30 Inuguration Hall A - Cultural Program 16:15-17:45 Plenary Session Plenary Session l Post transplant metabolic syndrome 16:30-18:30 Public Event on Organ Donation l Post-transplant HUS 17:15-18:15 Cases Discussion (3 Nephrology and 3 cases) Inauguration Entertainment & Banquet / Gala Entertainment 18:30 Inaugural Dinner at Venue End of Conference Role of registry in transplantation: on the beach 18:15-18:30 Noble Gracious, Trivandrum 4 ISOT Newsletter May to August 2015 May to August 2015 ISOT Newsletter 5

Plenary & Renal Scientific Programme Concurrent Session Liver Concurrent Session Heart & Lung

3rd October 2015 4th October 2015 2nd October 2015 - Day One 2nd October 2015 - Day One Time Topic Time Topic Time Topic Time Topic All hands on Deck – First Dual hand Transplant Vidya Acharya Memorial Oration - Overview and challenges facing Heart Transplantation INSTRUCTION COURSE: Setting up a basic science 11:15-11:30 in India - 20 mins Anti body mediated rejection - 30 mins research lab - 15 mins each in India Pancreas transplantation in India - Tolerance from the lab to bedside - Birgit Sawitzki, Berlin Organ Donation Scenario in India with special reference 07:30-08:15 l Legal considerations 11:30-11:45 Coming of Age - 20 mins - 20 mins l Scope of basic science research to Tamil Nadu Logistics challenges and “Jugaad” in deceased organ Still the enemy within - Post transplant lympho l Applying for grant SESSION: 1 - Clinical Assessment donation and transplantation in India - 3 cases - 20 min proliferative disease - 20 mins 08:30-11:00 08:30-11:00 l Pre Transplant Preparation - Workup and clinical Improving the deceased Donation rate in Pennsylvania/ Long term survival of renal allografts - 20 mins SESSION: 1 - Acute Liver Failure Session approach to Heart Failure/Heart Transplant patients Philadelphia - Gift of Life Model - 20 min - 30 mins each Role of transplant ID physicians - 20 mins - 20 mins l Various faces of ALF ITHO Act - 2011 - What is Good & What is bad what l Pediatric Heart Failure - Indications and clinical Timeline of infections In SOT recipients - 20 mins 11:15-13:15 11:45-13:25 the clinicians should know? - 20 min l Acute Liver drug toxicity workup prior to tx - 30 mins l Presidential Talk - 30 min Dr. K N Udupa Memorial Lecture - 20 mins Hepatocyte transplant in ALF l Mechanical assist as a bridge to Heart Transplant l Auxillary Liver Transplantation 11:00-11:15 Tea / Coffee Break 11:00-11:15 Tea / Coffee Break - 30 mins FREE PAPER PRESENTATION Paired kidney exchanges:-an idea whose time has come? 13:15-14:00 Lunch Break l Use of organ care system in Tranporting donor heart 11:15-12:15 Concurrent session in other Halls 11:15-11:45 Indian perspective - 15 mins SESSION: 2 - 15 mins each and lung - 20 mins International Perspective - 15 mins Debate - 30 mins l Tricks of trade in LDLT 13:25-14:00 Lunch Break 12:15-12:45 Open - 15 mins Debate : Minimization versus Avoidance 14:00-15:00 l Posterior Sector LDLT SESSION: 2 - Recipient and Donor issues in Heart Robotic Transplant -15 mins 11:45-12:15 Avoid CNIs - 15 mins l Live donor liver tx Robotics Transplant Minimize CNIs - 15 mins 12:45-13:45 General Body Meeting l Minimal Invasive Donor hepatectomy l The Canadian National Transplant program – learning 12:15-13:15 FREE PAPER PRESENTATION Lunch Break - Symposia SESSION: 3 - 30 mins each 14:00-15:00 experience - 20 mins 13:15-14:15 Lunch Break - Symposia l Challenges of transport of sick patients for heart Mtor inhibitors- where to place as l HCC with vascular invasion – Down staging & transplant - 15 mins 13:45-14:30 immunosupression -15 mins Well begun is half done - The rationale for induction 15:00-16:00 Impact on Transplant - Transplant or no Transplant l Donation after Clinical death - 25 mins Post transplant fungal infection - 15 mins 14:15-15:25 therapy - 20 mins l Liver Transplant In Acute Alcoholic Hepatitis: Steroid avoidance in Renal Transplantation - 20 mins Discussion - 15 mins To do or Not To do SESSION: 3 - Technical issues in Heart Transplant Renal transplant in Diabetics - 15 mins Complications in transplantations - Symposium l Operative challenges in heart transplant - 20 mins - 80 mins Renal transplant in elderly - 15 mins rd 15:00-16:00 l CABO incompatible heart transplants - 20 mins l Post-transplant anemia - 15 mins 15:25-16:25 6 interesting cases from nephrology side 3 October 2015 - Day Two l Challenges of perioperative management and 14:30-15:50 l Recurrence of Ds post transplants - 15 mins intensive care - 20 mins 16:25-17:00 Debate : To deplete vs Not to deplete Time Topic l New onset diabetes after Transplantation - 15 mins 17:00 Valedictory and Public functions l Malignancies Post transplantation - 20 mins 07:30-08:15 Pump Workshop rd l Challenges posed by repeat KTR - 15 mins Session 1 : Intestinal failure & bridge to 3 October 2015 - Day Two Transplantation - 25 Mins each 15:50-16:00 Tea / Coffee Break 11:15-12:30 l Marginal Donor & Recipient – How Do We Balance Time Topic Kidney transplants - Surgical Case Discussions - www.isot2015.com l Is it Renal failure, AKI or HRS? SESSION: 1 - Immunology/Basics of Heart 60 mins l ?????? Transplantation l Graft Kidney with injuries & lesions - to take or not l Immunology of antibody mediated rejection l Perfusion & Bench Dissection for Donor - 12:30-13:15 General Body Meeting 11:15-12:25 - 20 mins How much to do & How to do. Lunch Break 16:00-17:00 13:15-14:00 l Non biopsy markers of rejection - 20 mins l Making Right kidney transplantation easier - Session 2 - l Inducing Immunological Tolerence and Accomodation What to do: Philips Thomas 2nd to 4th October 2015, Chennai, India l Nutrition in liver failure patients - 25 Mins in Heart Lung Transplants - 30 mins l en bloc kidney transplantation: 14:00-16:00 l Setting Up A Liver Transplant Program - l Drop in urine output post transplant - on table, after SESSION: 2 - Lung Transplant Lessons for Young Surgeons - 15 Mins closure after 3 hrs, after 24 to 48 hrs, after 5th day l Current outcomes in lung transplants in Australia l Free Paper Presentation - 1 hour 20 Mins 12:25-13:30 - 20 mins PLENARY EVENING 16:00-16:15 Tea / Coffee Break l Lung Transplant - Our experience - 20 mins Hepatitis C - New kids on the block making a difference l Outcomes of VV ECHMO - 25 mins 17:00-17:20 Session 3 - 15 mins each - 20 mins l Who Needs It? 13:30-14:00 Lunch Break Deceased Organ Donor - Symposium - 60 mins l Preoperative OptimizationSurgical l 16:15-17:15 SESSION: 3 - PRO versus CON Debates ECD in Deceased Donor Transplantation l Challenges in Paediatric Liver Transplantation l LVAD vs Heart Transplant - 20 mins l Perfusion, Packing the Organ for Transportation & l Nuances in Postoperative Care of Paediatric Liver 14:00-15:00 Documentation l ECMO followed by Heart Transplants - 20 mins 17:20-18:20 Transplantation l l Creatinine high on donor Kidney - to take or not to CNI free immunosuppression protocols - 20 mins take: CONTACT: Tel: +91 44 26447000 / +91 9444607000 SESSION: 4 - Symposium on Interesting Cases l 15:00-16:00 Multivisceral Transplantation for Slow Growing Email: [email protected] / [email protected] l 6 Cases Abdominal Tumours: Sepsis in deceased donation 19:30 Cultural Evening 4 ISOT Newsletter May to August 2015 May to August 2015 ISOT Newsletter 5

Concurrent Session Infections Concurrent Session Transplant Concurrent Session Reconstructive Concurrent Session Critical Care in Transplantation Pathology & Immunology & Hand Transplantation & Anaesthesia in Transplantation

2nd October 2015 - Day One 2nd October 2015 - Day One 3rd October 2015 4th October 2015 Time Topic Time Topic Time Topic Time Topic Management of febrile neutropenia in the era of 08:00-08:30 SESSION: 1 - Liver & Heart Transplant Pathology Panel Discussion - Basic issues in Reconstructive SESSION: 1 - Heart & Lung Transplant - 20 mins each multiresistant bacteria l Approach to liver allograft dysfunction - 20 mins Transplant l Pre operative workup of Heart Transplant patients Types of stem cell transplants and implications for l Recurrent diseases in liver allograft - 20 mins l Donor and recipient selection criteria l 08:30-09:15 11:15-12:15 Anaesthetic Challenges of heart Lung block infection l Ethical , legal and psychological issues Transplant Discussion 09:00-10:20 09:15-09:45 Infections in HSCT recipients- Indian data 09:00-11:00 l Pre op Preparation , counseling and informed l Anaesthetic Challenges in VAD placement and Role of Case Discussions consents TEE 09:45-11:00 Panel Discussion-Cases in Hem-Onc or HSCT recipients Case based approach to Symposium l Heart Transplant from DCD donor. 11:00-11:15 Tea / Coffee Break 1 Acute liver allograft dysfunction - 2 cases 2 Chronic liver allograft dysfunction - 2 cases l Donor Organ procurement and preparation of hand 10:20-10:40 Tea / Coffee Break 11:15-11:45 Pre transplant screening and vaccination l Surgical techniques of hand transplant 11:00-11:15 Tea / Coffee Break SESSION: 2 - Liver Transplant - 20 mins each Panel Discussion 12:15-13:15 l Surgical techniques of face transplant l Recent updates on Coagulation monitoring and How l Advances in Microbiology to help the transplant SESSION: 2 - Transplant Pathology l Immunosuppression and regulation of drugs to optimize coagulation to minimize transfusion (Role physician l Nephrologists' perspective: Renal biopsy in graft 11:45-13:15 l Post transplant monitoring and protocol/guidelines of Anti-fibrinolytics, Factor VIIa, PCC etc) l Role of gene sequencing dysfunction - 20 mins l Rehabilitation after transplant surgery 10:40-12:00 l Marginal : The challenges for the anaesthetist! l PCR based platforms for respiratory viruses and l Diagnosis of border line and acute T cell mediated bacteria rejection with Banff schema- 20 mins 13:15-14:00 Lunch Break l Management of patients with Pulmonary 11:15-13:05 l Acute antibody mediated rejection- 20 mins Hypertension 13:15-14:00 Lunch Break l Diagnosis of Chronic active antibody mediated Logistics l Choice of intra operative IV Fluids in the Cirrhotic 14:00-14:30 Infection control in transplant rejection and Transplant glomerulopathy - 20 mins 14:00-14:40 l Setting up a skin bank patients. l Drug induced changes in renal allograft biopsy l Setting up hand and face transplant program 14:30-15:15 Antimicrobial prophylaxis in solid organ transplantation - 20 mins SESSION: 3 - Kidney/ Multi visceral/ Bowel Transplant 15:15-16:00 Clostridium difficile-epidemiology & management options Discussion - 10 mins Debates - 20 mins each l Cost effectiveness of reconstructive transplant l Recent advances in anaesthesia for Kidney 16:00-16:15 Tea / Coffee Break 14:40-15:40 13:05-14:00 Lunch Break l Present and Future and beyond hand and face Transplantation. 13:00-14:00 16:15-16:45 Safe living after transplantation SESSION: 3 l Outcome and life after reconstructive transplant l Challenges for the anaesthetist in Multi Visceral l Transplant Panel Discussion - Approach to CMV viruses Recurrent diseases in renal allograft - 20 mins l Role of nurses in reconstructive transplantation l l Serological testing l The role of electron microscopy in renal graft Reperfusion Syndrome: Preparation and the 14:00-15:00 surgery Challenges! l CMV Prophylaxis in India dysfunction - 20 mins 15:40-16:00 l Role of Transplant co ordinators and grief counselors 16:45-18:15 l Histological diagnosis of infections after renal l CMV Treatment and resistance in reconstructive transplant 14:00-16:00 Session IV : Critical Care l Management of blips: when to start and stop transplant - 20 mins l Immune monitoring 16:00-16:30 Tea / Coffee Break Management of Brain stem dead donor.: Challenges in SESSION: 4 Case Discussions-Renal allograft biopsies 14:00-14:20 family counselling and Role of protocols in the Intensive General Body Meeting Case – 1 Ac T Cell Rej 16:30-17:30 Care Unit for optimization of Organs. rd Case – 2 ABMR ISRT (Indian Society for Reconstructive Transplant) 3 October 2015 - Day Two Case – 3 TG Panel Discussion 15:00-16:15 Time Topic Case – 4 CNI Tx l What is stopping intensive care to certify somebody Case – 5 Rec GN 3 14:20-15:00 brain dead and introduce organ donation? MDR Gram negatives - microbiology and management Case – 6 Post Tx infection l 07:30-08:30 perspectives Systemic hinderances (8min case +2 Min discussion) l Medicolegal issues Plenary 1: Role of an ID physicians in the transplant team 10:00-11:00 Plenary 2: Timeline of infections in SOT SESSION: 5 - Transplant Immunology Debate - Fast Tracking extubation in Liver transplant l Role of HLA in Allograft Monitoring - kidney, liver, 15:00-15:20 11:00-11:15 Tea / Coffee Break Recipients: PROS/CONS heart - 15 mins Panel Discussion l Overview on DSA testing modalities and its clinical 16:15-17:15 Sepsis & Rejection in the early Postoperative period- l Spectrum and epidemiology of Invasive fungal significance in renal transplantation - 15 mins 15:20-15:40 Challenges in the diagnosis and treatment infections in India l Transplantation tolerance - 15 mins 11:15-12:15 l Risk Stratification / Prophylaxis l Urinary and plasma biomarkers in renal allograft Role of TEE for pre-operative assessment, intra operative 15:40-16:00 l Diagnosis rejection - 15 mins and postoperative uses l Management strategies 12:15-13:15 General Body Meeting 1 2 5 6 13:15-14:00 Lunch Break Influenza in transplant recipients 14:00-14:30 4 Panel Discussion - Tuberculosis l Pretransplant screening and Prophylaxis 14:30-16:00 l Treatment of acute tuberculosis on Immuno- suppression with special reference to OLT recipients 3. MGR Memorial, Chennai l Considerations in the era of MDR and XDR TB 4. Vivekanad Rock Memorial, Kanyakumari 5. Velankanni Church, Chennai 16:00-16:15 Tea / Coffee Break 1. Ramkrishna Math, Chennai 6. Meenakshi Temple, Madurai 16:15-18:00 Panel Discussion - Cases in SOT recipients 2. Valluvar Kottam, Chennai 4 ISOT Newsletter May to August 2015 May to August 2015 ISOT Newsletter 5

Dinesh Babu Chennai M Salim Nazar Srinagar Rajan Ravichandran Chennai SL Tulani Dinesh Jothimani Chennai M Subba Rao Chennai Rajasekar Perumala Chennai SN Mehta National faculties Dinesh Khullar M Vijaykumar Chennai Rajeev Annigeri Bangaluru Sonal Asthana International Dipankar Bhowmik New Delhi Madhu Shankar Chennai Rajendiran Chennai Sorabh Kapoor ISOT 2015 Diwakar Chennai Mahesh Gopashetty Chennai Rajendra Pandey Kolkatta Soumitra Bagchi Delhi Faculties ISOT 2015 Dolly Daniel Vellore Mahesha V Bangalore Rajendran Chennai Sreebhushan Raju Edwin Fernando Chennai Mammen Chandy Vellore Rajesh NG Pondicherry Sreejith Parameswaran Pondicherry Firoz Sonawala Mumbai Manav Wadhawan New Delhi Rajesh Prabhu Madurai Sreelatha M Calicut Prof Manikkam Suthanthiran The NewYork-Presbyterian-Weill Cornell A Huligol Bangalore G H Mallik Srinagar Manav Wadhwan Delhi Rajiv Karthik Vellore Sridhar N Chennai Medical Center (NYP-WCMC) A K Barman Guwahati G Karthikeyan Chennai Manish Rathi Rajiv Soman Mumbai Subhash Gupta New Delhi A K Bhalla New Delhi Ganapathy Chennai Manish Varma Hyderabad Ram Gopal Krishnan Chennai Subramaniam Iyer Cochin Dr Ira J Fox MD A K Vaidya Ranchi Ganesh Gopalakrishnan Coimbatore Manisha Sahay Hyderabad Ram Subramanian Chennai S Swaminathan Chennai McGowan Institute for Regenerative Medicine A Khakhar Chennai Gangadhar Reddy Hyderabad Manoj Jain Lucknow Rama Mani Chennai Suceena Alexander Vellore Mr Howard M Nathan A Majumdar Kolkatta Geeta Billa Mumbai Matthew Jacob Bangalore Ramachandran Menon Kochi Sudarshan Ballal Bangalore Gift of Life Donor Program Philadelphia, PA A Murali Chennai Geetha Kalpana Chennai Matthew Cochin Ramalingam Chennai Sudhindran Cochin A Murthy Hyderabad George Chandy Chennai Maya Menon Chennai Ramasubramaniam Chennai Sudipta Roy Kolkata Dr Manjula Balasubramanian George Kurian Pondicherry MG Rajamanickam Chennai Ramdas Pischarody Trivandrum Suhas Salpekar Einstein Medical Center Philadelphia, PA A S Soin Gurgaon Abha Nagral Mumbai George M Varghese Vellore Mohammed Rela Chennai Ramesh D Bangalore Sujata Patwardhan Mumbai Dr Victor Navarro Abhay Mahajan Aurangabad Georgi Abraham Chennai Mohan Rajapurkar Nadiad Ranganathan Iyer Hyderabad Sujoy Pal New Delhi Jefferson Medical College Philadelphia, PA Abraham Kurian Chennai Gokulnath Bangalore Mohit Sharma Cochin Ranjan Mohapatra Chennai Sumana Navin Chennai Aditya Pradhan Chennai Gomathy Narasimhan Chennai MS Ansari Lucknow Ratan Jha Hyderabad Sundeep Vijayaraghvan Prof Gurch Randhawa Gourdas Choudhuri Gurgaon Mukul Vij Chennai Ravi Mahajan Haryana Suneetha Narreddy Hyderabad Professor of Diversity in Public Health and Ajay Chennai H S Kohli Chandigarh Murali Venkatraman Chennai Ravi Mohanka Mumbai Sunil Prakash New Delhi Director, Institute for Health Research, Alan Almeida Mumbai Harsh Jauhari New Delhi Murli Chennai Ravi Raya Hyderabad Sunil Shroff Chennai University of Bedfordshire Alok Kumar Dehradun Amalopavanathan J Chennai Hemal Kaninde Chennai Muthu Jayaraman Chennai Ravi Shankar Haryana Surendran Chennai Prof Hariharan Iyer Amit Gupta Lucknow Hemant Kumar Patna Muthu Ramaswamy Chennai Ritambhara Nada Chandigarh Suresh Rao Chennai Schulich School of Medicine & Dentistry, Amresh Mumbai Himanshu Mahapatra New Delhi Muthusethupathy Chennai Ronica Baruah Guwahati Swarnalatha G Hyderabad London Health Sciences Center, Western Anand Khakar Chennai Ilamparuthi Chennai N Gopalakrishnan Chennai S Asthana Bangalore T Sunder Chennai University, London, Ontario, Canada Anand Ramamurthy Chennai Ilannkumaran Chennai N Jayram Bangalore S C Das Bhubaneshwar T Ravi Raju Hyderabad Anant Kumar Delhi Imtiyaz Ahmed Srinagar N Murugan Chennai S Jasuja New Delhi T T Paul Thrissur Prof Birgit Sawitzki J P Ojha Varanasi N Sharad Kumar Manipal S K Agarwal Lucknow Tarun Jeloka Pune Institute of Medical Immunology at the Charité Aneesh Srivastav Luchnow J P Tiwari Goa Naimish Mehta Delhi S K Agarwal New Delhi Thangam Menon Chennai University in Berlin Anil Vaidya Chennai Anila Abraham Chennai J Thanka Chennai Narayan Prasad Lucknow S K Sarin Noida Thiagrajan K Chennai Prof Chandrasekar P H Anita Cherian Thiruvananthapuram Jacob George Trivandrum Neeraj Saraf Gurgaon S Padmanabhan Bangalore Tomar Jaipur Karmanos Cancer Institute Detroit Anita Dinda Chennai Jai Kumar Chennai Neerav Goyal New Delhi S R Balakrishnan Chennai Uday Ghoshal Lucknow Anupam Saha New Delhi Jai Ram New Delhi Nitin Kekre Vellore S Ramalakshmi Chennai Umesh Lingarajan Bangalore Prof Ajit P. Limaye Jamal Rizvi Mumbai University of Washington, Seattle, USA Anupam Sibal New Delhi Nitya Krishnan Chennai S Sahariya Hyderabad Umesh Oza Mumbai Anusha Rohit Chennai Jayakumar Chennai NK Mohanty Bhubaneshwar S Subramanian Iyer Cochin Urmila Anand Mumbai Prof George Alangaden Archana Rastogi Delhi Jayant Thomas Mathew Thrissur Noble Gracious Trivandrum S Subramanian Chennai V Balaji Vellore Wayne State University Infectious Diseases, Aroghya Majumdar Kolkata Jayaraman Chennai Om Kumar Patna S Sunder Bangalore V G Mohan Coimbatore CFP-316 Arpita Roy Chaudhary Kolkata Jerry Paul Chennai P P Varma New Delhi S. Saravanan Chennai V Mahesha Bangalore Jimmy Cochin P Soundararajan Chennai Sampath Kumar Madurai V N Unni Kochi Dr Mayur S Ramesh Arti Vij Delhi Henry Ford Hospital 2799 West Grand Blvd Aruna Vanikar Ahmedabad Jitendra Kumar Faridabad P V L N Murthy Hyderbad Sandeep Agawal New Delhi V S Mehta New Delhi Arvind Bagga New Delhi Jitin Kothari Mumbai Pallav Gupta Delhi Sandeep Guleria New Delhi V S Saraswat Lucknow Prof Amitabh Gautam ASatish LaL Madurai Jose Chako Pariappan Cochin Pari Chennai Sandeep Mahajan New Delhi V Tamilarasi Vellore Boston Medical Center Ashok Kirpalani Mumbai Joseph John Ludhiana Paul Dinakaran Chennai Sandeep Saxena Indore Wani Mohd Saleem Srinagar Dr Nithya Krishnan Balajee Chennai Joy Michael Vellore Paul Ramesh Chennai Sandeep Kerala Vasantha Roopan Chennai University Coventry and Balaraman Chennai Joy Varghese Chennai Philip Thomas Cochin Sandhya Srinivasan Chennai Vasudevan Trivandrum Warwickshire NHS Trust, U.K Bhanumati Vellore K C Prakash Chennai Pitchai Chennai Sanjeev Gulati New Delhi Veena Chennai Bharat Shah Mumbai K L Gupta Chandigarh Poovizhi Chennai Sanjeev Kanoria Mumbai Venugopalan G Trivandrum Dr Anirban Bose Bhattacharya Chennai K M Cherian Chennai Prabha Senguttuvan Chennai Sanjeev Nair Chennai Vijay Kher New Delhi Associate Professor of Medicine and K M Sahu Ranchi Prahlad N Chennai Santosh Kumar Chennai Vijay Vohra Delhi Nephrology at the University of Rochester, NY Biju George Vellore Biju Pottakat Pondicherry K R Balakrishnan Chennai Pranjal Modi Ahmedabad Santhosh Varghese Vellore Vijayanand P Coimbatore Dr George T John C E Eapen Vellore K R Palaniswamy Chennai Prashant Ghosh Delhi Sarah Kuruvilla Chennai Vijaykumar Chennai Senior Consultant in Renal Medicine at the C M Thiagarajan Chennai K S Nayak Hyaderabad Pratik Das Kolkatta Satish Balan Cochin Vinay Kumaran Mumbai Royal Brisbane and Women's Hospital, C R Kar Bhubaneshwar K Sampath Kumar Madurai Praveen Varma Chennai Satish Chennai Vinay Malhotra Jaipur Australia Chandrasekhar Chennai K Sridhar Chennai R G Singh Varanasi Saubhik Sural Kolkatta Vinay Pathak Tamiladu Chitra Madiwale Mumbai K V Dakshinamurty Bangalore R K Dhiman Chandigarh Seethalekshmy NV Kochi Vinita Agarwal Lucknow Dr Chandraker A Col Gopi Delhi Kaiser Raja Bangalore R K Sharma Lucknow Shailesh Raina Mumbai Vinod Rai Hyderabad Medical Director of Kidney and Pancreas Kamal Kanodia Ahmedabad R Krishnammoorthy Chennai Shalimar New Delhi Vivek Kute Ahmedabad Transplantation and Director of the Transplant D K Pahari Kolkata D Ramesh Bangalore Kesava Kumar Chennai R N Sahoo Sheetal Dhadphale Pune Vivek Pathak Coimbatore Research Center at Brigham and Women's D S Bhadauria Lucknow Kishore Cochin R Raghevendran Chennai Sheo Kumar Tirupati Vivekanada Jha Chandigarh Hospital/Harvard Medical School D S Rana New Delhi Krishnamurthy Chennai R Raghuveer Hyderabad Shishir Gang Nadiad Vivekanandan Bangalore Dr Rodrigo Vianna Daphnee Chennai Lakshmi Kumar Trivandrum R Ravikumar Chennai Shrirang Bichu Mumbai Yogesh K Chawla Chanidgarh University of Miami/Jackson Memorial Deepak Dubey Bangalore Lalitha Raghuraman Hyderabad R Vijaykumar Chennai Shruti Tapiawala Mumbai Zacharia Paul Kochi Hospital, Miami, US Dharmesh Kapoor Hyderabad Luis Bakero Chennai Rahul Kakodkar Mumbai Sidhe Pune Dilip Dhanapal Bangalore M G Rajamanickam Chennai Rajan Duggal Delhi Sivaraman Chennai 10 ISOT Newsletter May to August 2015 May to August 2015 ISOT Newsletter 11

e c e a s e d d o n a t i o n 26th Annual Conference of ISOT, 2 - 4 October 2015, Chennai transplantation in India is now Dgradually moving forward. In the NOMINATIONS / APPLICATIONS INVITED last two years we have seen the Deceased donation rate in India FOR ISOT ORATION AWARDS AND FELLOWSHIP doubling of the deceased donation rate from 196 donors in 2012 or 0.16 per Dr. J. M. Patel Oration million population (pmp) to 411 in 2014 doubles in the last two years This award is intended to recognize outstanding contribution by the member of or 0.34 pmp. The figures may not look impressive enough, but when you Sunil Shroff ISOT in the field of Organ Transplantation that significantly advances the field of MOHAN Foundation, 3rd Floor, 267 Kilpauk Garden Road, Chennai 600010, India organ transplantation in India. Any member can apply for this Award. The consider that these figures are of only 10 application along with six copies of CV, topic of Oration and the original work of states and union territories (UTs) of India the member done in India in relation to the topic of the Oration should reach the and the donations resulted in 1150 solid Secretariat before 25th August 2015. The Scientific Committee of the ISOT is the organs like kidney, liver, heart, lung, 5. Cooperation between public and was in the hospital domain and not in many instances the initial 'No' for evaluating authority for this Award. pancreas and intestine and thus it does private hospitals in the states that among the public. They believed that donation was converted to 'Yes'. This Award: Plaque and Shawl become significant. Rather than looking have done well when with the doctor from ICU spoke to fact is important for the hospital the relatives of the family of a deceased authorities to understand, if they wish to at the national average, it may be better 6. Specialist Intensive care doctors Dr. R. V. S. Yadav Oration donor along with a trained co-ordinator, take this programme forward. to look at the state wise figures and who have been supportive of the Applicant should be member or has to apply for ISOT membership to be eligible many states have crossed 1 or 2 programme for this award. This Oration is awarded to a senior Transplantation Surgeon who donations per million population. It also has contributed significantly to the practice and teaching of Organ means that deceased donation 7. Awareness among the public and Transplantation in India. The awardee will be selected by the Scientific Committee transplantation is now responsible for t h e i r s u p p o r t t o w a r d s t h e of the ISOT. The application must reach to the Secretariat before 25th August almost 40% of the liver transplants done programme 2015 in the country and over 15% of kidney 8. Role of NGO's like MOHAN Award: Plaque and Shawl transplants. Foundation in helping with capacity Dr. K. N. Udupa Memorial Lecture The few states that have led the way building and creating awareness forward include Tamil Nadu, Kerala, among the public and in hospitals. This award is reserved for outstanding research work done by ISOT members Andhra Pradesh, Maharashtra, below the age of 40. The application along with six copies of CV, topic of lecture Tamil Nadu has continued to contribute and the original work of the member done in India in relation to the topic of the Karnataka, Gujarat, Uttar Pradesh, substantially to the number of deceased lecture should reach the Secretariat before 25th August 2015. The Scientific P o n d i c h e r r y, D e l h i - N C R a n d donors and is the only state where the Committee is the evaluating authority for this Award. Chandigarh second tier cities like Coimbatore, Award: Certificate and Medallion The factors that have been responsible Madurai, Trichy, Vellore, Salem and for this increase in the numbers are as Tirunelveli have had deceased donors. Novartis Transplant Fellowship follows - This speaks highly not only about the Applicant should be a member or has to apply for ISOT membership to be eligible programme, but also the availability of for this award. Trainee has to be post MD or post MS (Medicine, Surgery or 1. Support of the media in promoting advanced medical facility in the state. Pathology or Basic science relevant to transplantation). Head of the Department the cause T h e l a s t a d v a n c e d t r a n s p l a n t of their Institute should certify that he/she is interested to work in Transplantation 2 . I n c r e a s e i n n u m b e r o f and will be given necessary leave if selected for the grant. The fellow selected will coordinators conference in Chennai h o s p i t a l s / c e n t r e s d o i n g conducted by MOHAN Foundation was spend minimum 2weeks at the selected centre. He will have to submit his report transplantation especially liver to the Secretary of ISOT. The last date for application submission 25th August attended by many senior coordinators 2015 3. Increase in number of trained from across the country. When they Award: The award will be Rs. 40,000/- (at the next conference) transplant coordinators in the were quizzed about where the programme challenge lay in the deceased donation INTRODUCING Dr Vidya Acharya Oration of ISOT programme in our country, most said it 4. State Government's proactive role This award is intended to recognize outstanding research work done by any in the programme in some of the International Faculty (preferably of Indian Origin) that significantly advances the states field of organ transplantation in India or, overseas. Any ISOT member can also apply for this Award whose research work has been exceptionally recognised. The Please send your nomination / applications application along with CV, a write up on the proposed to the Secretariat : Oration based on original work in relation to the topic Dr. Narayan Prasad, of the Oration should reach the Secretariat before Secretary ISOT 25th Aug 2015. The Scientific Committee and ISOT Department of Nephrology councils are the evaluating authority for this Award. Sanjay Gandhi Postgraduate Award: Plaque and Shawl Institute of Medical Sciences, Lucknow, India-226014 Last Date : Tuesday 25th August 2015 Deceased Multi-Organ Donors in India No. of Deceased Multi-Organ Donors Reference and Source – Indian Transplant newsletter - Vol. 14 Issue No.: 44 March 2015 – June 2015 Email: [email protected] 12 ISOT Newsletter May to August 2015 May to August 2015 ISOT Newsletter 13

Review Article We have developed the technique of in Table 1: Experience using AD-MSC in living donor renal transplantation The major advantage using AD-MSC is vitro AD-MSC generation without using that patients return to mainstream of life xenogeneic material. We have then with ≤ 2 immunosuppressants, less developed our own protocol for living rejections and minimum infections. donor renal transplantation using these Financial burden on the system is stem cells. (Figure1) significantly reduced due to lesser requirement of medications and Figure 2: (A) Kaplan Meier graph morbidity as compared to controls on Mesenchymal stem cells and depicting patient survival of protocol standard triple immunosuppression and control groups. Protocol patients regime. transplant tolerance underwent infusion of adipose derived m e s e n c h y m a l s t e m c e l l s a n d Future 1 2, 3 hematopoietic stem cells and controls Aruna V Vanikar , Hargovind L Trivedi Ashutosh Kumar , We have also generated in vitro, 4 2 were transplanted without stem cells. Saroj Chooramani Gopal , 5, Vivek B Kute regulatory T cells which have further Patient as well as combined patient + improved our results. 1. Department of Pathology, Laboratory Medicine, Transfusion Services graft survival was significantly better in and Immunohematology. IKDRC and ITS, Ahmedabad, India. 2. Department of Nephrology and Transplantation Medicine, protocol group vs. controls. References IKDRC and ITS, Ahmedabad, India. 1. Trivedi HL, Vanikar AV, Patel HV, Kute 3. Department of Hematology, KGMU Hospital, Lucknow, India. (B) Kaplan Meier graph depicting death 4. Department of Pediatric Surgery, Institute of Medical Sciences, censored renal allograft survival of VB, Dave SD. Regulatory T-cells support Banaras Hindu University, Varanasi, India. protocol and control groups. Protocol stem cell therapy in safe minimization of 5. Department of Pediatric Surgery, KGMU Hospital, Lucknow, India. p a t i e n t s w e r e u n d e r ≤ 2 immunosuppression in living donor renal transplantation. J Stem Cell Res immunosuppressants and controls Ther 2014; 4(10):1-8. w e r e u n d e r s t a n d a r d t r i p l e immunosuppression. Statistical 2. Vanikar AV, Trivedi HL.T-Regulatory significance was not seen (p=0.02). Cells: The Recently Recognized Players of Immunomodulation. J Stem Cell Res Abstract in induction of transplant tolerance © Graph depicting graft survival as Ther 2014; 4(10):1-6. including when to use them and how to Different strategies are being tried to noted in UNOS data, CTSE data and 3. Trivedi HL, Vanikar AV, Kute VB, et al. induce transplant tolerance in clinical use them for achieving the Utopian IKDRC-ITS, Ahmedabad data * (D) The effect of stem cell transplantation settings; however, none of them are dream of transplant tolerance. Kaplan Meier graph depicting patient + on immunosuppression in living donor both safe and effective. Mesenchymal Supplementary renal allograft survival of protocol and renal transplantation: A clinical trial. Int J stem cells have been found to be potent control groups. Org Transplant Med 2013; 4 (4): 155- Experience Of Renal Transplantation 162. immunomodulators and immuno- *Gondos A, Dohler B, Brenner H, Opelz suppressants. We discuss in this review Using Donor Adipose Tissue Derived Mesenchymal Stem Cells (AD-MSC) G.Kidney graft survival in Europe and different sources of mesenchymal stem the United States: strikingly different cells and the potent role of adipose And Hematopoietic Stem Cells (HSC) In IKDRC-ITS, Ahmedabad long-term outcomes. Transplantation tissue-derived mesenchymal stem cells 2013 Jan 27; 95(2):267-74.

Delhi: The department of Nephrology PGIMER, Dr R M L Hospital and AIIMS jointly India Observes World Kidney Day on 12 March 2015 organised a conference on World Kidney Day at the institute’s auditorium. Chennai: TANKER FOUNDATION, Distributed leaflets and water bottles to the general public on the World Kidney Day 2015. Delhi Chennai Odisha: Students of Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar participate in a rally to create awareness on World Kidney Day 2015. Kolkata: Paediatric Nephrology unit of Fortis Hospital, Kolkata celebrated World Kidney Day where an interactive session was Figure 1: Ahmedabad protocol for minimization of Figure 2: (A) Kaplan Meier graph organized between parents and children who immunosuppression in living donor renal transplantation using have undergone transplant. stem cells, (A) Recipient Protocol (B) Donor Protocol Odisha Kolkata 14 ISOT Newsletter May to August 2015 May to August 2015 ISOT Newsletter 15

NEWS Head transplant: Russian man to become first SPOTTED to undergo pioneering and controversial surgery ANNOUNCEMENT OF EVENTSFORTHCOMING he first man set to undergo a head medical experts called the procedure The procedure was carried out on a monkey transplant has been revealed, saying unlikely, and rare, as well as highlighting the in 1970. But surgeons didn't transplant the The 26th Annual Conference of Indian Tthat he finds the controversial surgery fact that it would never be used for those that spinal cord, so the monkey could not move, Society of Organ Transplantation is “very scary, but also very interesting”. simply want to replace an ailing body. Some and it lived for only nine days and died when ISOT ELECTIONS scheduled from 2nd to 4th October 2015 at have even compared Canavaro to the head was rejected by the body's immune Valery Spiridinov is set to be the first person Chennai. For further details contact: Frankenstein. system. to undergo the operation. It will be carried Secretariat for ISOT 2015 Conference, out by controversial Italian doctor Sergio The head transplant is set to work by taking It has never been done on a human, but President (Physicians) - 1 MOHAN Foundation,3rd Floor, 267 Kilpauk Canavero, whose optimistic plans have the head off a person suffering from a Canavaro claims that all the necessary Garden Road, Chennai -600010, India; mostly been met with scepticism. wasting or degenerative disease, and science and technology is now in place. “I Tel:-91 44 26447000 / 91 9444607000; transplanting it onto the body of someone think we are now at a point when the President Elect (Surgeon) - 1 E - m a i l : i n f o @ i s o t 2 0 1 5 . c o m o r But Spiridonov — who has the rare genetic who is braindead but still has a functioning technical aspects are all feasible,” Canavaro [email protected] Werdnig-Hoffman disease, which gradually body. It would be akin to the process of has said. wastes away muscles — says that he is TTS 2015 14th Transplantation Science moving organs into a body — but would rely willing to undergo the risky procedure to give g of Nomination Symposia scheduled from November 11- on the donor's family giving away the entire Last date himself a chance at living in a healthy body. 13, 2015 at Lorne, Australia. For further body, rather than just parts of it. Sumbmission - 31st August 2015 details contact: tts2015.org. “Am I afraid? Yes, of course I am. But it is not just very scary, but also very interesting,” ILTS 22nd ILTS Annual International Spiridonov, speaking from his house in the Congress will be held at Seoul, South Korea Russian town of Vladimir about 120 miles Download Nomination Froms from from May 4-7, 2016. For further details from Moscow, told MailOnline. www.isot.co.in contact: http://www.ilts.org “But you have to understand that I don't 52nd ERA-EDTA Congress is scheduled really have many choices,” he said. “If I don't from May 21-24 at Viana, Australia. For try this chance my fate will be very sad. With f u r t h e r d e t a i l s c o n t a c t : w w w. e r a - every year my state is getting worse.” edta2016.org Spiridinov said that he has spoken with Dr ISOT Council Members American Transplant Congress 2016 will Canavaro over Skype but they are yet to be held at John B. Hynes Convention Center, meet. The Russian man was chosen from a Post Name Email ID Boston, MA from June 11-15, 2016. Abstract Submission Deadline: December number of people that emailed and wrote to President Dr. Umesh Oza [email protected] Canavaro to ask to undergo the procedure, 4, 2015.For further details contact; he said. Vice-Presidents Dr. Aruna Vanikar [email protected] http://2016.atcmeeting.org/ Canavaro raised scepticism earlier this year Dr. Sanjeev Gulati [email protected] 6th International Congress of The when he said that he would be able to carry Dr. Aneesh Srivastava [email protected] Transplantation Society will be held in Hong out the procedure within two years. Other Kong from the 18th to the 23rd August 2016. Secretary Dr. Narayan Prasad [email protected] F o r f u r t h e r d e t a i l s c o n t a c t : Joint Secretary Dr. Sudhir Kulkarni [email protected] http://www.tts2016.org/ Zion appeared at the hospital's news Zion, of Owings Mills, Md., outside Treasurer Dr. Alan F Almeida [email protected] Maryland 8-year-old is conference with his forearms bandaged, but Baltimore, contracted sepsis at age 2. The his hands visible. He demonstrated his still- resulting multiple organ failure forced the Council Dr. Sanjay K Agarwal [email protected] Randy’s youngest to receive double delicate grip and described waking up with amputation of his hands and feet; by age 4, Dr. Sunil Shroff [email protected] Laughing Corner new hands as "weird at first, but then good." he needed a kidney transplant, receiving the hand transplant organ from his mother. Dr. Gopal Basu [email protected] "He woke up smiling," said Dr. L. Scott Levin, Dr. Manish Rathi [email protected] who heads the hand transplant program. Leg prosthetics have allowed Zion to be very maryland boy who lost both his hands "There hasn't been one whimper, one tear, active, including walking, running and Dr. Sandip Saxena [email protected] to an infection while a toddler became one complaint." jumping. He learned to use his forearms to the youngest patient to receive a Dr. LK Tripathi [email protected] A write, eat and play video games and has successful double hand transplant, been attending school. Physicians hope he'll Dr. Manisha Sahay [email protected] surgeons announced Tuesday. now be able to achieve more milestones, Dr. Dhanajai Agarwal [email protected] Surgeons at The Children's Hospital of including his goals of throwing a football and Philadelphia told a news conference they playing on the monkey bars. "It was no more Immediate Past President Dr. Ashok L. Kirpalani [email protected] operated on Zion Harvey for nearly 11 hours of a risk than a kidney transplant," his mother, Editor, IJT Dr. Raj Kumar Sharma [email protected] earlier this month. A 40-person team used Pattie Ray, said. "So I felt like I was willing to steel plates and screws to attach the old and take that risk for him, if he wanted it — to be Correspondence: Dr. Narayan Prasad, Secretary, Indian Society of Organ Transplantation, new . Surgeons then painstakingly able to play monkey bars and football.” Additional Professor, Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical reconnected Zion's arteries, veins, muscles, Sciences, Raebareli Road, Lucknow-226014, INDIA c Email: [email protected] Zion, (8) the receipient of a successful double The donor's family chose to remain and nerves. c Mobile: +91-9415403140 c Ph.: +91-522-2495187 (O), 2495188 (R) “Good News — they found you hand transplant, at a press conference anonymous. g a donor for a smile transplant!”