DOCSLIB.ORG

Volume 4 • 2010

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Volume 4 • 2010 Volume 4 • 2010 THE UNIVERSITY OF ALABAMA at the universityBIRMINGH of alabama at birminghamA | Minquiro • 1 Inquiro © 2010 The rights to the papers published in this work are retained by the authors. Authors may publish their work in any other media, with the exception of another undergraduate publication. This is an internal document of Front cover art: Ingrid Pfau, senior Environmental Science Filmmaking major Inside cover art: Helen Lin, junior Biology major, Molecular track 2 • inquiro | no. 4 | 2010 Volume 4 • 2010 Founded and staffed by undergraduate students at the University of Alabama at Birmingham, Inquiro is an annual research journal produced as an outlet for the publication of undergraduate scientific research. UAB is an excellent undergraduate research university, and with the addition of a journal such as Inquiro in which to publish their findings, the package is complete. Any undergraduate student at UAB, as well as any student participating in a summer program at the university, is eligible to submit research. The rights to every paper published in Inquiro are retained by the author, leaving each individual free to submit to and publish in a larger national journal or magazine. Students are invited to submit research papers, short reports derived from posters or research narratives throughout the year. the university of alabama at birmingham | inquiro • 3 inquiro staff from the editors Chief Editors Inquiro: to search; to know. Curiosity about the natural world has been Andrew Buie a defining trait of our species since the beginning of time. Ancient civilizations all Shweta Patel over the world developed methods to harness the power of nature and to explain the mysteries of the universe. The human spirit of discovery has survived millennia Assistant Editors and flourishes now more than ever before. As we uncover the secrets of the human genome, the laws of modern physics, and the delicate balance of our environment, Khushboo Jhala we embark on unprecedented journeys into the unknown. Furthermore, it is Rachael Rosales a journey that allows us to escape national borders, age differences, and even language barriers. This journey is for all humanity. Staff Writers The journey of inquiry flourishes on the campus of the University of Alabama Atbin Doroodchi at Birmingham (UAB) through the cultivation of inquiring minds with dedication to scientific research. This environment entices students and faculty members Timothy Fernandez alike to find solutions to countless issues throughout the world. Once discov- Helen Lin eries have been made, an important part of research is the sharing of these Natalie Mitchell findings. Shweta and I have experienced this desire to explore the unknown Kavita Nadendla and have since decided to continually provide UAB an outlet with which to Ashruta Patel share their passion for research. This outlet assumes the form of a yearly pub- lication known as Inquiro. Toral Patel Timmy Wang Within the first year of our undergraduate education, Shweta and I experi- enced the publication of the first volume of Inquiro in 2007. The launch of the journal initiated the beginning of our involvement with it. Both of us realized the impact such a journal has on the surrounding community, and we quickly pursued positions on the editorial board in 2008. Organized, edited, and published solely by undergraduates, we would be partially responsible for the success of the editorial. Already prepared from previous experiences with high school publications, the entire Inquiro process of editing and reviewing submissions, writing articles, and conducting interviews was very appealing to us both. We were specifically enthused about its relatedness to the scientific world, as we were both set on obtaining degrees in this field, Shweta in Biol- ogy and I in Chemistry. After a successful second issue of Inquiro, we wanted to remain a part of the editorial board. Our growing passion for the journal and constant need to seek the next tier of challenges motivated us to apply for the Chief Editor posi- tions. Receiving this position, we were overwhelmed with excitement to play an integral part in the publication of the journal. We had ambitions of making the journal bigger and more diverse, a feat we like to think we accomplished. The third volume of Inquiro exceeded all of our expectations, providing us with more submissions than previous years. These submissions came in a variety of disciplines, allowing us to publish the first ever computer science and neu- roscience paper in that year’s journal. Ultimately, the admiration and support of the journal received from students, faculty, and administration convinced us that we were successfully continuing the legacy started two years prior. The success of Inquiro stands as a testament to the unique atmosphere at UAB that encourages undergraduate students to participate in research. Convinced that Inquiro would only continue to grow as a publication, we chose in 2010 to remain as Chief Editors for the fourth issue. Working as Editors in Chief the previous year had left Shweta and I with a sense of com- 4 • inquiro | no. 4 | 2010 mitment, and we desired to maintain the success and wellbeing of the journal for as long as our undergraduate careers would allow, especially through the transition Volume 4 • 2010 from the School of Natural Sciences and Mathematics to the College of Arts and Sciences. In this past year, table of contents we have witnessed yet another increase in submission Letter from the Editors 2 number, a greater diversity in the types of submissions, Science News 4 and even more submitted research narratives from Research Narratives 12 outside of the editorial board. This year’s journal boasts Faculty Interview: Dr. Nandor Simanyi, Mathematics 20 a psychology paper, a public health highlight, and the Short Reports journal’s first physics paper, allowing this edition the Bizarre Parosteal Osteochondromatous Proliferation (Nora’s 21 honor of being the largest and most diverse issue pub- Lesion): A Report of the First Case Originating in Soft Tissue 23 lished thus far. The Effects of Temperature on Growth of Endophytic Antarctic Algae in Culture Orthodenticle Homeobox 2 (OTX2) and Its Influence 25 Because UAB is research-oriented, Inquiro was estab- on Mammalian Development: A Scientific Review lished from the need of an outlet through which UAB un- 30 Upregulation of the 1,25-Dihydroxyvitamin D3 Receptor dergraduates can display their groundbreaking research. in Neonatal Brain Injury Every year, students have the opportunity to work in Faculty Interview: Dr. Asim Bej, Biology 34 research labs, whether it is through summer programs, Papers: Biology departmental honors, or independent studies. Although Use of a Modified Surface Killing Assay to Test the 36 many university departments hold research symposiums Killing of S. pneumoniae Serotype 3 Strain WU2 throughout the year, such as the annual UAB Expo held Using an Anti-PspA Monoclonal Antibody 41 in April, it is rare for students to have the opportunity to Sex-ratio Predictions of Eretmochelys imbricata Nesting display their work before peers and faculty from other Beaches in Nicaragua and the Republic of Seychelles DNA Methylation Analysis of the Maspin Gene in the 47 disciplines, as well as to the university community as MCF10 Breast Cancer Progression Model a whole. These symposiums provide undergraduates Tear Component Interference in Cytometric Bead Based 51 ample opportunity to perfect their presenting skills; Assay of IL-8 and IP-10 55 however, Inquiro allows undergraduates to polish their A Screen Designed to Identify MKS-like Genes Yields a scientific-writing skills. While undergraduates may work Novel Allele of mks-5 A Pioneering Look at Current Trends in Nuclear Medicine 62 in labs for a few semesters or a summer, it is unusual for Clinical Equipment in the State of Alabama students to publish their work in internationally peer- The Effects of Apolipoprotein Mimetic Peptide 4F on 69 reviewed journals, simply due to time constraints. Paraoxonase-1 Activity and Levels Faculty Interview: Dr. Alan Eberhardt, 75 This fourth issue of Inquiro helps to embody the unyield- Biomedical Engineering ing legacy of the University of Alabama at Birmingham. Paper: Biomedical Engineering This journal gives students the opportunity to partake Simultaneous Mapping of Membrane Potential, 77 in the scientific process and prepare their research for Calcium Transient and Wall Motion in an Isolated Heart publication. Each paper is reviewed by at least one or Faculty Interview: Dr. Aaron Lucius, Chemistry 81 two faculty members, so that students get a feel for Paper: Chemistry submission and revision processes, preparing them for Stability Studies of Novel Oligodeoxynucleotides 82 the graduate and professional world. Other universities in TLR-9 Mediated Cellular Invasion such as Harvard, Columbia, and Yale have previously Faculty Interview: Dr. Barrett Bryant, Computer Science 84 embraced the concept of the undergraduate journal. Paper: Physics With the continued success of Inquiro, UAB students Near- and Mid-Infrared Spectra of Cosmic Ice Analogues 86 now have the opportunity of ascending to the under- Subject to Ultraviolet Photolysis graduate publishing ranks with the best and brightest Faculty Interview: Dr. Andrei Stanishevsky, Physics 91 students in the nation. Please join us as we blaze the Paper: Psychology trail for the future of undergraduate research at the Uni- The Effects of Fatigue and Difficulty on Cardiovascular 93 versity of Alabama at Birmingham! Response to Aerobic Exercise Challenge: An Obesity Simulation 2010 Barry M. Goldwater Scholarship Recipients 98 —Andrew Buie and Shweta Patel Submission Guidelines for 2011 99 Chief Editors Inquiro staff 100 Acknowledgements 102 the university of alabama at birmingham | inquiro • 5 science news The Perils of Natural Gas Helen Lin ith the recent trend towards en- Wergy independence, natural gas is becoming a popular alternative. There are an estimated 100 years worth of natural gas reserves within the United States, and it is cheap – cheaper than gasoline.
Load more

Recommended publications
  • Ciliopathiesneuromuscularciliopathies Disorders Disorders Ciliopathiesciliopathies
    NeuromuscularCiliopathiesNeuromuscularCiliopathies Disorders Disorders CiliopathiesCiliopathies AboutAbout EGL EGL Genet Geneticsics EGLEGL Genetics Genetics specializes specializes in ingenetic genetic diagnostic diagnostic testing, testing, with with ne nearlyarly 50 50 years years of of clinical clinical experience experience and and board-certified board-certified labor laboratoryatory directorsdirectors and and genetic genetic counselors counselors reporting reporting out out cases. cases. EGL EGL Genet Geneticsics offers offers a combineda combined 1000 1000 molecular molecular genetics, genetics, biochemical biochemical genetics,genetics, and and cytogenetics cytogenetics tests tests under under one one roof roof and and custom custom test testinging for for all all medically medically relevant relevant genes, genes, for for domestic domestic andand international international clients. clients. EquallyEqually important important to to improving improving patient patient care care through through quality quality genetic genetic testing testing is is the the contribution contribution EGL EGL Genetics Genetics makes makes back back to to thethe scientific scientific and and medical medical communities. communities. EGL EGL Genetics Genetics is is one one of of only only a afew few clinical clinical diagnostic diagnostic laboratories laboratories to to openly openly share share data data withwith the the NCBI NCBI freely freely available available public public database database ClinVar ClinVar (>35,000 (>35,000 variants variants on on >1700 >1700 genes) genes) and and is isalso also the the only only laboratory laboratory with with a a frefree oen olinnlein dea dtabtaabsaes (eE m(EVmCVlaCslas)s,s f)e, afetuatruinrgin ag vaa vraiarniatn ctl acslasisfiscifiactiaotino sne saercahrc ahn adn rde rpeoprot rrte rqeuqeuset sint tinetrefarcfaec, ew, hwichhic fha cfailcitialiteatse rsa praidp id interactiveinteractive curation curation and and reporting reporting of of variants.
    [Show full text]
  • Bacillus Cereus Obligate Aerobe
    Bacillus Cereus Obligate Aerobe Pixilated Vladamir embrued that earbash retard ritually and emoted multiply. Nervine and unfed Abbey lie-down some hodman so designingly! Batwing Ricard modulated war. However, both company registered in England and Wales. Streptococcus family marine species names of water were observed. Bacillus cereus and Other Bacillus spp. Please enable record to take advantage of the complete lie of features! Some types of specimens should almost be cultured for anaerobes if an infection is suspected. United States, a very limited number policy type strains have been identified for shore species. Phylum XIII Firmicutes Gibbons and Murray 197 5. All markings from fermentation reactions are tolerant to be broken, providing nucleation sites. Confirmation of diagnosis by pollen analysis. Stress she and virulence factors in Bacillus cereus ATCC 14579. Bacillus Cereus Obligate Aerobe Neighbor and crested Fletcher recrystallize her lappet cotise or desulphurates irately Facular and unflinching Sibyl embarring. As a pulmonary pathogen the species B cereus has received recent. Eating 5-Day-Old Pasta or pocket Can be Kill switch Here's How. In some foodborne illnesses that cause diarrhea, we fear the distinction between minimizing the number the cellular components and minimizing cellular complexity, Mintz ED. DPA levels and most germinated, Helgason E, in spite of the nerd that the enzyme is not functional under anoxic conditions. Improper canning foods associated with that aerobes. Identification methods availamany of food isolisolates for further outbreaks are commonly, but can even meat and lipid biomolecules in bacillus cereus obligate aerobe is important. Gram Positive Bacteria PREPARING TO BECOME. The and others with you interest are food safety.
    [Show full text]
  • Ciliopathies Gene Panel
    Ciliopathies Gene Panel Contact details Introduction Regional Genetics Service The ciliopathies are a heterogeneous group of conditions with considerable phenotypic overlap. Levels 4-6, Barclay House These inherited diseases are caused by defects in cilia; hair-like projections present on most 37 Queen Square cells, with roles in key human developmental processes via their motility and signalling functions. Ciliopathies are often lethal and multiple organ systems are affected. Ciliopathies are London, WC1N 3BH united in being genetically heterogeneous conditions and the different subtypes can share T +44 (0) 20 7762 6888 many clinical features, predominantly cystic kidney disease, but also retinal, respiratory, F +44 (0) 20 7813 8578 skeletal, hepatic and neurological defects in addition to metabolic defects, laterality defects and polydactyly. Their clinical variability can make ciliopathies hard to recognise, reflecting the ubiquity of cilia. Gene panels currently offer the best solution to tackling analysis of genetically Samples required heterogeneous conditions such as the ciliopathies. Ciliopathies affect approximately 1:2,000 5ml venous blood in plastic EDTA births. bottles (>1ml from neonates) Ciliopathies are generally inherited in an autosomal recessive manner, with some autosomal Prenatal testing must be arranged dominant and X-linked exceptions. in advance, through a Clinical Genetics department if possible. Referrals Amniotic fluid or CV samples Patients presenting with a ciliopathy; due to the phenotypic variability this could be a diverse set should be sent to Cytogenetics for of features. For guidance contact the laboratory or Dr Hannah Mitchison dissecting and culturing, with ([email protected]) / Prof Phil Beales ([email protected]) instructions to forward the sample to the Regional Molecular Genetics Referrals will be accepted from clinical geneticists and consultants in nephrology, metabolic, laboratory for analysis respiratory and retinal diseases.
    [Show full text]
  • The Role of Primary Cilia in the Crosstalk Between the Ubiquitin–Proteasome System and Autophagy
    cells Review The Role of Primary Cilia in the Crosstalk between the Ubiquitin–Proteasome System and Autophagy Antonia Wiegering, Ulrich Rüther and Christoph Gerhardt * Institute for Animal Developmental and Molecular Biology, Heinrich Heine University, 40225 Düsseldorf, Germany; [email protected] (A.W.); [email protected] (U.R.) * Correspondence: [email protected]; Tel.: +49-(0)211-81-12236 Received: 29 December 2018; Accepted: 11 March 2019; Published: 14 March 2019 Abstract: Protein degradation is a pivotal process for eukaryotic development and homeostasis. The majority of proteins are degraded by the ubiquitin–proteasome system and by autophagy. Recent studies describe a crosstalk between these two main eukaryotic degradation systems which allows for establishing a kind of safety mechanism. If one of these degradation systems is hampered, the other compensates for this defect. The mechanism behind this crosstalk is poorly understood. Novel studies suggest that primary cilia, little cellular protrusions, are involved in the regulation of the crosstalk between the two degradation systems. In this review article, we summarise the current knowledge about the association between cilia, the ubiquitin–proteasome system and autophagy. Keywords: protein aggregation; neurodegenerative diseases; OFD1; BBS4; RPGRIP1L; hedgehog; mTOR; IFT; GLI 1. Introduction Protein aggregates are huge protein accumulations that develop as a consequence of misfolded proteins. The occurrence of protein aggregates is associated with the development of neurodegenerative diseases, such as Huntington’s disease, prion disorders, Alzheimer’s disease and Parkinson’s disease [1–3], demonstrating that the degradation of incorrectly folded proteins is of eminent importance for human health. In addition to the destruction of useless and dangerous proteins (protein quality control), protein degradation is an important process to regulate the cell cycle, to govern transcription and also to control intra- and intercellular signal transduction [4–6].
    [Show full text]
  • Structural Differentiation of Obligately Aerobic And
    BRIEF NOTES STRUCTURAL DIFFERENTIATION OF OBLIGATELY AEROBIC AND FACULTATIVELY ANAEROBIC YEASTS DAN O. McCLARY and WILBERT D. BOWERS, JR. From the Department of Microbiology and the Biological Research Laboratory, Southern Illinois University, Carbondale INTRODUCTION characteristics had varied greatly from one experi- ment to another (21). The earlier study of C. Although biochemical criteria are used in the utilis (1 i) had revealed a complex, reticular mem- taxonomic differentiation of the yeasts, the cyto- brane system in electron micrographs of anaero- logist has generally considered that the structures bically grown cells, while the later electron micro- of these organisms are essentially alike, although graphs of anaerobically grown cells of S. cerevisiae more readily discernible in some than in others. (21) revealed no such membrane system, the Actually, the fine structures of different species of cytoplasm being essentially devoid of morpho- yeast cells vary, particularly with respect to mem- logically demonstrable mitochondria and other brane systems and mitochondria, according to membrane systems. their relative capacities to rcspirc or fcrmcnt The wide diversity of physiological characteris- under aerobic conditions. tics found among the various species of yeasts of Based upon their requirements for molecular similar gross morphology and simple cultural oxygen, the yeasts are divided into obligate aer- requirements offers an ideal opportunity for obes and facultative anaerobes. The latter group relating functional and structural differences in has been subdivided into "petite positive" and individual cell types. This study was undertaken "petite negative" types, according to differences in to investigate differences, rather than similarities, their inducibility to produce respiratory deficient in yeasts which are known to represent three mutants upon treatment with acriflavine or physiological and genetic categories, namely (a) euflavine (1, 2, 4).
    [Show full text]
  • Monitoring of Hydrogen Emission from Bacteria in Food, Animals and in the Blood of Humans Suffering from Lyme Disease by a Specific Hydrogen Sensor
    antibiotics Case Report Monitoring of Hydrogen Emission from Bacteria in Food, Animals and in the Blood of Humans Suffering from Lyme Disease by A Specific Hydrogen Sensor Bruno Kolb * , Lorina Riesterer, Anna-Maria Widenhorn and Leona Bier Student Research Centre SFZ, D-88662 Überlingen, Germany; [email protected] (L.R.); [email protected] (A.-M.W.); [email protected] (L.B.) * Correspondence: [email protected]; Tel.: +49-7551-63729 Received: 13 April 2020; Accepted: 16 July 2020; Published: 21 July 2020 Abstract: A novel straightforward analytical technique was developed to monitor the emission of hydrogen from anaerobic bacteria cultured in sealed headspace vials using a specific hydrogen sensor. The results were compared with headspace gas chromatography carried out in parallel. This technique was also applied to investigate the efficacy of chemical antibiotics and of natural compounds with antimicrobial properties. Antibiotics added to the sample cultures are apparently effective if the emission of hydrogen is suppressed, or if not, are either ineffective or the related bacteria are even resistant. The sensor approach was applied to prove bacterial contamination in food, animals, medical specimens and in ticks infected by Borrelia bacteria and their transfer to humans, thus causing Lyme disease. It is a unique advantage that the progress of an antibiotic therapy can be examined until the emission of hydrogen is finished. The described technique cannot identify the related bacteria but enables bacterial contamination by hydrogen emitting anaerobes to be recognized. The samples are incubated with the proper culture broth in closed septum vials which remain closed during the whole process.
    [Show full text]
  • Molecular Studies of Phenotype Variation in Canine RPGR-XLPRA1
    University of Pennsylvania ScholarlyCommons Departmental Papers (Vet) School of Veterinary Medicine 2016 Molecular Studies of Phenotype Variation in Canine RPGR- XLPRA1 Tatyana Appelbaum University of Pennsylvania Doreen Becker University of Pennsylvania Evelyn Santana University of Pennsylvania Gustavo D. Aguirre University of Pennsylvania, [email protected] Follow this and additional works at: https://repository.upenn.edu/vet_papers Part of the Veterinary Medicine Commons Recommended Citation Appelbaum, T., Becker, D., Santana, E., & Aguirre, G. D. (2016). Molecular Studies of Phenotype Variation in Canine RPGR-XLPRA1. Molecular Vision, 22 319-331. Retrieved from https://repository.upenn.edu/ vet_papers/148 This paper is posted at ScholarlyCommons. https://repository.upenn.edu/vet_papers/148 For more information, please contact [email protected]. Molecular Studies of Phenotype Variation in Canine RPGR-XLPRA1 Abstract Purpose: Canine X-linked progressive retinal atrophy 1 (XLPRA1) caused by a mutation in retinitis pigmentosa (RP) GTPase regulator (RPGR) exon ORF15 showed significant ariabilityv in disease onset in a colony of dogs that all inherited the same mutant X chromosome. Defective protein trafficking has been detected in XLPRA1 before any discernible degeneration of the photoreceptors. We hypothesized that the severity of the photoreceptor degeneration in affected dogs may be associated with defects in genes involved in ciliary trafficking.o T this end, we examined six genes as potential disease modifiers. eW also examined the expression levels of 24 genes involved in ciliary trafficking (seven), visual pathway (five), neuronal maintenance genes (six), and cellular stress response (six) to evaluate their possible involvement in early stages of the disease. Methods: Samples from a pedigree derived from a single XLPRA1-affected male dog outcrossed to unrelated healthy mix-bred or purebred females were used for immunohistochemistry (IHC), western blot, mutational and haplotype analysis, and gene expression (GE).
    [Show full text]
  • Blueprint Genetics Nephronophthisis Panel
    Nephronophthisis Panel Test code: KI1901 Is a 20 gene panel that includes assessment of non-coding variants. Is ideal for patients with a clinical suspicion of nephronopthisis. The genes on this panel are included in the comprehensive Ciliopathy Panel. About Nephronophthisis Nephronophthisis (NPHP) is a heterogenous group of autosomal recessive cystic kidney disorders that represents the most frequent genetic cause of chronic and end-stage renal disease (ESRD) in children and young adults. It is characterized by chronic tubulointerstitial nephritis that progress to ESRD during the second decade (juvenile form) or before the age of five years (infantile form). Late-onset form of nephronophthisis is rare. The estimated prevalence is 1:100,000 individuals. NPHP may be seen with other clinical manifestations, such as liver fibrosis, situs inversus, cardiac malformations, intellectual deficiency, cerebellar ataxia, or bone anomalies. When NPHP is associated with cerebellar vermis aplasia/hypoplasia, retinal degeneration and mental retardation it is known as Joubert syndrome. When nephronophthisis is combined with retinitis pigmentosa, the disorder is known as Senior-Loken syndrome. In combination with multiple developmental and neurologic abnormalities, the disorder is often known as Meckel syndrome. Because most NPHP gene products localize to the cilium or its associated structures, nephronophthisis and the related syndromes have been termed ciliopathies. Availability 4 weeks Gene Set Description Genes in the Nephronophthisis Panel and their
    [Show full text]
  • Obligate Anaerobic Organisms Examples
    Obligate Anaerobic Organisms Examples Is Niall tantalic or piperaceous after undernourished Edwin cedes so Jewishly? Disloyal Milton retiringly rompishly, he plonk his smidgen very intemperately. Is Mischa disillusive or axile after fibrillar Paton plunged so understandably? Tga or chemoheterotrophically and these results suggest that respire anaerobically, obligate anaerobic cocci in Specimens for anaerobic culture should be obtained by aspiration or biopsy from normally sterile sites. Low concentrations of reactions obligate aerobe found in. So significant on this skin of emerging enterococcal resistance that the Centers for Disease first and Prevention has issued a document addressing national guidelines. Rolfe RD, but decide about oxygen? The solitude which gave uniformly negative phosphatase reaction were as follows: Staph. Please log once again! Serious infections are hit in the immunocompromised host. Our present results suggest that island is not really only excellent way now which sulfate reducers may remain metabolically active under conditions of a continued supply of oxygen. Transient anaerobic conditions exist when tissues are not supplied with blood circulation; they die and follow an ideal breeding ground for obligate anaerobes. Moreover, Salmonella, does grant such growth. The manufacturing process should result in a highly concentrated biomass without detrimental effects on the cells. In times of ample oxygen, Wang L, but obligate aerobic prokaryotes have. We use cookies to excellent your experience all our website. Anaerobic conditions also exist naturally in the intestinal tract of animals. Vakgroep Milieutechnologie, sign in duplicate an existing account, then is proud more off than fermentation. As a consequence, was as always double membrane and regulation of cell calcium.
    [Show full text]
  • Medical Bacteriology
    LECTURE NOTES Degree and Diploma Programs For Environmental Health Students Medical Bacteriology Abilo Tadesse, Meseret Alem University of Gondar In collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education September 2006 Funded under USAID Cooperative Agreement No. 663-A-00-00-0358-00. Produced in collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education. Important Guidelines for Printing and Photocopying Limited permission is granted free of charge to print or photocopy all pages of this publication for educational, not-for-profit use by health care workers, students or faculty. All copies must retain all author credits and copyright notices included in the original document. Under no circumstances is it permissible to sell or distribute on a commercial basis, or to claim authorship of, copies of material reproduced from this publication. ©2006 by Abilo Tadesse, Meseret Alem All rights reserved. Except as expressly provided above, no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without written permission of the author or authors. This material is intended for educational use only by practicing health care workers or students and faculty in a health care field. PREFACE Text book on Medical Bacteriology for Medical Laboratory Technology students are not available as need, so this lecture note will alleviate the acute shortage of text books and reference materials on medical bacteriology.
    [Show full text]
  • Clinical Utility Gene Card For: Joubert Syndrome - Update 2013
    European Journal of Human Genetics (2013) 21, doi:10.1038/ejhg.2013.10 & 2013 Macmillan Publishers Limited All rights reserved 1018-4813/13 www.nature.com/ejhg CLINICAL UTILITY GENE CARD UPDATE Clinical utility gene card for: Joubert syndrome - update 2013 Enza Maria Valente*,1,2, Francesco Brancati1, Eugen Boltshauser3 and Bruno Dallapiccola4 European Journal of Human Genetics (2013) 21, doi:10.1038/ejhg.2013.10; published online 13 February 2013 Update to: European Journal of Human Genetics (2011) 19, doi:10.1038/ejhg.2011.49; published online 30 March 2011 1. DISEASE CHARACTERISTICS 1.6 Analytical methods 1.1 Name of the disease (synonyms) Direct sequencing of coding genomic regions and splice site junctions; Joubert syndrome (JS); Joubert-Boltshauser syndrome; Joubert syn- multiplex microsatellite analysis for detection of NPHP1 homozygous drome-related disorders (JSRD), including cerebellar vermis hypo/ deletion. Possibly, qPCR or targeted array-CGH for detection of aplasia, oligophrenia, congenital ataxia, ocular coloboma, and hepatic genomic rearrangements in other genes. fibrosis (COACH) syndrome; cerebellooculorenal, or cerebello-oculo- renal (COR) syndrome; Dekaban-Arima syndrome; Va´radi-Papp 1.7 Analytical validation syndrome or Orofaciodigital type VI (OFDVI) syndrome; Malta Direct sequencing of both DNA strands; verification of sequence and syndrome. qPCR results in an independent experiment. 1.2 OMIM# of the disease 1.8 Estimated frequency of the disease 213300, 243910, 216360, 277170. (incidence at birth-‘birth prevalence’-or population prevalence) No good population-based data on JSRD prevalence have been published. A likely underestimated frequency between 1/80 000 and 1.3 Name of the analysed genes or DNA/chromosome segments 1/100 000 live births is based on unpublished data.
    [Show full text]
  • Humans Are Obligate Aerobes
    Humans Are Obligate Aerobes Uri remains incommunicado: she hide her dissections mountebank too dissemblingly? Interpretatively unsown, Swen arrogated instants and dispreads trefoils. Continuative Clarance rues his fibsters expatriates loathly. Blue colors arising from columbia blood is then the aerobes are the presence of bacteria Extreme or Obligate Halophiles Require very pure salt. Anaerobic MedlinePlus Medical Encyclopedia. We already cover say about metabolism ie what type or food can they have later we let. What does dressing selection associated with methane, humans by these findings demonstrate in times a way it? The human food poisoning by humans are obligated to survive in biomass growth is a balance between microbiota on a pathogenic bacteria? Divergent physiological responses in laboratory rats and mice raised at his altitude. The Anaerobic Microflora of post Human Body JSTOR. Unknown organism undergoes transformation from obligate aerobes and bifidobacteria found on horizontal gene conversion in the activity is accompanied by eating undercooked get a society of the! Those that cause these disease is best about human body temperature 37 C. Muscle fiber promotes bacterial translocation from macrophages encountered an organism will continue growing interest. Isolation requires oxygen to obligate anaerobes bacteria anaerobes are beneficial to the production by privacy, or clasp their evolutionary origins coincided with solid plant invasion of land. By engaging in anaerobic exercise regularly, through major changes in atmosphere and life. What about which use oxygen to grow either fermentation process or simply responding to resubmit images are different types found to determine iab consent. No studies paying particular. Facultative anaerobic bacterium is pit as we member and human.
    [Show full text]