Fusaproliferin, a Fungal Mycotoxin Shows Cytotoxicity Against Pancreatic Cancer Cell Lines
Fusaproliferin, a Fungal Mycotoxin Shows Cytotoxicity against Pancreatic Cancer Cell Lines. Nazia Hoque 1,3,4, Choudhury Mahmood Hasan 2, Md. Sohel Rana 3, Amrit Varsha5, Md. Hossain Sohrab 4*and Khondaker Miraz Rahman 5* 1 Department of Pharmacy, East West University, Dhaka, Bangladesh 2 Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka-1000, Bangladesh 3 Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh 4 Pharmaceutical Sciences Research Division (PSRD), BCSIR Laboratories, Dhaka, Bangladesh 5 School of Cancer and Pharmaceutical Science, King's College London, 150 Stamford Street, London SE1 9NH, UK Supporting Information 1. The Plant Aglaonema hookerianum Schott In this study we investigated the fungal endophyte Fusarium solani, isolated from petiole of Aglaonema hookerianum Schott (Family:Araceae) growing in the forest of Sylhet and Chittagong Hill tracks of Bangladesh.It is a herb, stem erect, 40-50 cm or more tall, 1.5-2.0 cm thick, internodes 1.5-3.0 cm long. Leaves petiolate, petiole up to 24 cm long and grows in the shady areas of deep forest. A large number of tribal populations like Chakma, Marma, Murong, Tongchongya, Tripura, Chak, Khasia, Rheyang, Rakhain, Khumietc live as forest inhabitants in the remote areas throughout Sylhet and the Chittagong Hill Tracts, where there is no or poor modern medical systems of health care. The majority of them are dependent on the traditional system of treatment, which includes various indigenous medicinal plants of those areas [1]. A. hookerianum,locally known as Habinishak, is used by the mainstream traditional practitioners of Sylhet district for the treatment of hemorrhoids and arthritis.
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