Anti-DCTN2 monoclonal antibody, clone FQS6106 (DCABH-2740) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Rabbit monoclonal to Dynamitin

Antigen Description Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase alignment and spindle organization during mitosis. Involved in anchoring to centrosomes. May play a role in synapse formation during brain development.

Immunogen Synthetic peptide corresponding to residues in Human Dynamitin (UniProt ID: Q13561).

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Clone FQS6106

Purity Tissue culture supernatant

Conjugate Unconjugated

Applications WB, IHC-P, ICC/IF, IP

Positive Control MCF7, A375, Saos2, and SH SY5Y cell lysates; SHSY5Y cells

Format Liquid

Size 100 μl

Buffer pH: 7.40; Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA

Preservative 0.01% Sodium Azide

Storage Store at -20°C. Stable for 12 months at -20°C

GENE INFORMATION

Gene Name DCTN2 dynactin 2 (p50) [ Homo sapiens ]

Official Symbol DCTN2

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms DCTN2; dynactin 2 (p50); dynactin subunit 2; DCTN 50; RBP50; p50 dynamitin; dynactin complex 50 kD subunit; dynactin complex 50 kDa subunit; 50 kD dynein-associated polypeptide; 50 kDa dynein-associated polypeptide; DCTN50; DYNAMITIN;

Entrez Gene ID 10540

Protein Refseq NP_006391

UniProt ID Q13561

Chromosome Location 12q13.3

Pathway Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem;

Function motor activity; binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved