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OCTOBER 2019 #81 Upfront In My View Solutions Sitting Down With The explosives experts Analytical power in METLIN: half a million Technician-turned-trailblazer, fingerprinting fireballs public hands and counting Dame Carol Robinson 11 15 – 16 44 – 46 50 – 51 www.theanalyticalscientist.com All the capability, none of the limits Choose from the widest range of powerful, easy-to-use solutions for routine and research trace elemental analysis Thermo Scientific™ trace elemental analysis instruments deliver quality, reproducible data from any sample type. With a streamlined and intuitive interface, our innovative solutions make it easy for operators at any experience level to analyze samples to meet even the strictest regulations and legislation. So you can have total confidence in your results. Expand your potential at thermofisher.com/TEA For Research Use Only. Not for use in diagnostic procedures. ª5IFSNP'JTIFS4DJFOUJmD*OD"MMSJHIUT SFTFSWFE"MMUSBEFNBSLTBSFUIFQSPQFSUZPG5IFSNP'JTIFS4DJFOUJmDBOEJUTTVCTJEJBSJFTVOMFTTPUIFSXJTFTQFDJmFE Image of the Month Crystal Maze A 2,5-hidroxybenzoic acid matrix-assisted laser desorption/ionization matrix cocrystallized with a fluorescein isothiocyanate- conjugated peptide. The sample was created by Ben Katz, a proteomics specialist at the University of California, Irvine, to improve resolution and lower background noise. Follow Ben on Twitter @ProteinMassSpec. Credit: Nicole Green, Iowa State University, USA. Would you like your photo featured in Image of the Month? Send it to [email protected] www.theanalyticalscientist.com Contents 10 08 50 03 Image of the Month Upfront In My View 08 Tipping the Scales 14 Native protein LC-MS 07 Editorial is leading the way in new The Power and The Passion by 10 Stimulating and Sensing assay technologies, says Matthew Hallam Insulin Secretion Matthew Lauber 11 Explosive Experimentation 15 Michel Nielen reflects on the On The Cover rise of citizen science in the 12 Lotion in the Ocean food industry Sometimes the simplest approach is best… The Power List 16 Naidong Weng discusses 2019 is here. how budding chemists can enjoynjoy a successful international careerreer Analthe ytical Scientist ISSUE 81 - OCTOBER 2019 Editor - Charlotte Barker [email protected] Deputy Editor - Matthew Hallam [email protected] Assistant Editor - Jonathan James [email protected] Scientific Director - Frank van Geel [email protected] Content Director - Rich Whitworth [email protected] Publishing Director - Lee Noyes [email protected] Business Development Manager - Gaurav Avasthi [email protected] Head of Design - Marc Bird [email protected] Designer - Hannah Ennis [email protected] Designer - Charlotte Brittain [email protected] Digital Team Lead - David Roberts [email protected] Digital Producer Web/Email - Peter Bartley [email protected] Digital Producer Web/App - Abygail Bradley [email protected] Audience Insight Manager DPO - Tracey Nicholls [email protected] Traffic & Audience Database Coordinator - Hayley Atiz [email protected] Project Manager - Webinars - Lindsey Vickers [email protected] Traffic Manager - Jody Fryett [email protected] Traffic Assistant - Dan Marr [email protected] Events Manager - Alice Daniels-Wright [email protected] Events Coordinator - Jessica Lines [email protected] Marketing Manager - Katy Pearson [email protected] Marketing Executive - Jo Baylay [email protected] Social Media Manager - Joey Relton [email protected] Financial Director - Phil Dale [email protected] Accounts Assistant - Kerri Benson [email protected] Chief Executive Officer - Andy Davies [email protected] Chief Operating Officer - Tracey Peers [email protected] 44 Senior Vice President (North America) - Fedra Pavlou [email protected] Commercial Director - Richard Hodson [email protected] Editorial Advisory Board Monika Dittmann, Agilent Technologies, Germany Norman Dovichi, University of Notre Dame, USA Gary Hieftje, Indiana University, USA Emily Hilder, University of South Australia, Australia Features Reports Ron Heeren, Maastricht University, The Netherlands Tuulia Hyötyläinen, University of Örero, Finland Hans-Gerd Janssen, Unilever Research and Development, The Netherlands Robert Kennedy, University of Michigan, USA Samuel Kounaves, Tufts University, USA 18 The Power List 2019: Top 100 13 Supercharging Spectrometry Martin Gilar, Waters, USA Luigi Mondello, University of Messina, Italy Celebrating the achievements Peter Schoenmakers, University of Amsterdam, The Netherlands Robert Shellie, Trajan Scientific and Medical, Australia Ben Smith, University of Florida, USA of the Top 100 most influential Frantisec Svec, University of California at Berkeley, USA Ian Wilson, Imperial College London, UK figures in the field Frank Bright, University at Buffalo, USA Chris Harrison, San Diego State University, USA 48 Spotlight On... Change of address [email protected] Technolog y Hayley Atiz, The Analytical Scientist, Texere Publishing Limited, Booths Park 1, Chelford Road, Knutsford, Cheshire, WA16 8GS, UK General enquiries Department www.texerepublishing.com [email protected] +44 (0) 1565 745 200 44 Solution: METLIN at 500k Sitting Down With [email protected] Distribution: by Gary Siudzak The Analytical Scientistt (ISS (ISSNN 2051-4 2051-4077), is published monthly by Texere Publishing LiLimited,d, 50 SittingSittin Down With… Booths Park 1, Chelfordrd Road, Knutsford, Cheshire,Che e, WA16 8GS, UK. Singlele copy sales £15 (plus postage,post Carol RRobinson, Professor of cost available on requestest info@[email protected] icalsienti com). Non-quaNon-qualifiedd annual annual subscription subscription cost cost is is Chemistry,Chemis University of £110£1 plus postagepostag Reprints & PermissionPermissions – [email protected]@texerepublishing.com Oxford,Oxford Oxford, UK The opinions presenteded withinwithin tthis publicationblication areare thosethose ofof thethe authorsauthors andand dodo nnot reflect the opinions of TheThe AnalyAnalytical Scientistentist or orits its publishers, publishers, Texere Texere Publishin Publishing. Authors are requiredd to disclose any relevantant financial arrangements, which arare presented at the endd of each article,ar where relevant. © 2017 Texerere Publishing Limited. All rightsts reservedreserved. Reproduction in wholeole or in parts iiss prohibitprohibited.ed make the difference The i-volution in HPLC analysis continues The popular i-Series of compact (U)HPLC systems has now Flexible software control evolved to the Plus family of Prominence-i and Nexera-i systems. by Shimadzu LabSolutions LC/GC, LC-MS or DB/CS for full The new line of products combines high-speed analysis with FDA 21 CFR Part 11 compliance. Software packages from other simplified method transfer, automated sample pre-treatment, vendors are also supported minimized environmental impact and easy maintenance. It tar- gets pharmaceutical, chemical and food industries. Significantly improved analytical productivity through automated pre-treatment functionality resulting in increased efficiency and reduced risk of human error Wide range of application fields such as R&D activities, specification tests and quality control Plus family Prominence and Nexera-i www.shimadzu.eu/i-series The Power and The Passion The Power List 2019 highlights the strengths of Editorial analytical science – and the community behind it he Power List 2019 has landed – a celebration of the top 100 most influential figures in analytical science. Curating the list (collecting nominations received Tfrom across the globe, working closely with our judging panel, and corresponding with all 100 nominees) has been a lengthy process – but also a privilege. Few fields are supported by a workforce that can lay claim to the level of dedication and passion that our community exudes. Whether speaking of fundamentals or applications, biology, the environment or beyond, it’s clear to see that immersion in this field is closely tied to a real belief in its purpose. And that’s likely why the field is so highly connected – and brimming with positivity. As Paul Bohn notes, we have “terrific colleagues all over the world,” and this translates not only into prime opportunities for enjoyable and fruitful collaboration, but also into a tightly knit network of support that helps propel each of us forward to tackle the problems ahead. To thrive, we must move with the times; as such, to quote Caroline West, analytical chemistry is “a dynamic science that changes rapidly.” The perpetual progress in our field is highlighted by advances in instrument miniaturization, usability and portability, and the application of artificial intelligence and automation. Increasingly, instrumentation is moving away from labs and into the real world. What’s more, the continuous streamlining of the analytical process means that these increasingly portable technologies are providing data that can be interpreted and used in record time. Of course, all of these endeavors feed into a single end
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