DOCSLIB.ORG

Morphosys Achieves Milestone in GPC Biotech Cancer Collaboration First Morphosys Antibody to Show Efficacy in Animal Models

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Morphosys Achieves Milestone in GPC Biotech Cancer Collaboration First Morphosys Antibody to Show Efficacy in Animal Models Press Release Martinsried/Munich, July 19, 2001 MorphoSys achieves Milestone in GPC Biotech Cancer Collaboration First MorphoSys Antibody to show Efficacy in Animal Models MorphoSys (Neuer Markt: MOR) and GPC Biotech (Neuer Markt: GPC) today announced the achievement of a pre-clinical milestone in GPC Biotech’s antibody program for the treatment of specific blood cancers, the MHC class II positive B-cell lymphomas. GPC Biotech showed that the human antibody generated and optimized by MorphoSys from its proprietary HuCAL® library had significant in vivo efficacy in rodent xenograft-tumor models. The milestone triggers an undisclosed payment from GPC Biotech to MorphoSys. The selected fully human HuCAL® antibody showed high affinity to the MHC class II target and was selected for in vivo studies because it efficiently and rapidly killed a series of human blood tumors in in vitro assays, including Non-Hodgkin’s lymphoma. Human Non-Hodgkin lymphoma cells and the selected antibody were injected into immune deficient mice and the antibody was shown to completely inhibit tumor growth in the majority of the cases or significantly delay it. ”This antibody is the first ever HuCAL-derived antibody confirming efficacy in animal models, and as such, represents an important achievement for us”, added Dr. Thomas von Rueden, Chief Scientific Officer, MorphoSys AG. “Today’s announcement is another significant step towards establishing a broad pipeline of HuCAL-derived antibodies heading into clinical development over the coming years.” Sebastian Meier-Ewert, Ph.D., Senior Vice President and Head of Research of GPC Biotech AG said: “The data from the in vivo model are very promising indicating that the antibody may prove to be an effective treatment for cancer patients with weakened immune systems resulting from conventional chemotherapy or other common cancer treatments. The efficacy data suggests that the MHC class II specific antibody kills tumor cells without the need for an immunological effector mechanism. The next step will be further pre-clinical studies in order to aggressively move this program into clinical development.” MorphoSys develops and applies innovative technologies for the production of synthetic antibodies, which accelerate drug discovery and target characterization. Founded in 1992, the Company's proprietary Human Combinatorial Antibody Library (HuCAL) technology is used by researchers worldwide for human antibody generation. The Company currently has licensing and research collaborations with Bayer (Berkeley, California/USA), Biogen Inc. (Cambridge, Massachusetts/USA), Centocor Inc. (Malvern, Pennsylvania/USA), Chiron Corp. (Emeryville, California/USA), DuPont Pharmaceuticals Inc. (Wilmington, Delaware/USA), Eos Biotechnology Inc. (San Francisco, California/USA), GPC Biotech AG (Munich/Germany), Hoffmann-La Roche AG (Basel/Switzerland), ImmunoGen Inc. (Cambridge, Massachusetts/USA), Millennium Inc. (Cambridge, Mass/USA) and ProChon Biotech Ltd. (Rehovot/Israel). GPC Biotech AG is a genomics- and proteomics-driven drug discovery company focused on applying a number of proprietary genomic, proteomic and drug discovery technologies to accelerate the identification and validation of novel drug targets for development of mechanism-based drugs in oncology, infectious diseases and immunology. GPC Biotech has leading cell cycle expertise and a broad intellectual property position with 59 patents issued, that are wholly owned, co-owned or exclusively/co-exclusively licensed, and over 180 patents pending. Drug discovery alliance partners include: Aventis Pharma (PAVE.PSE), Bayer AG (BAY.FSE), DuPont Pharmaceuticals (DD-B.NYS), Boehringer Ingelheim GmbH, the Altana AG (ALT.FSE) subsidiary Byk Gulden, Cell Genesys, Inc. (CEGE.NAS), Evotec OAI AG (EVT.FSE), MorphoSys AG (MOR.FSE) and Karo Bio USA (KARO.SSE). GPC Biotech AG is headquartered in Martinsried/Munich (Germany) with two wholly owned US subsidiaries in Waltham/Boston, MA and in Princeton, NJ. For further information, please visit the corporate website at: http://www.gpc-biotech.com. Statements included in this press release which are not historical in nature are intended to be, and are hereby identified as, “forward-looking statements” for purposes of the safe harbour provided by Section 21E of the Securities Exchange Act of 1934, as amended by the Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by words including “anticipates”, “believes”, “intends”, “estimates”, “expects” and similar expressions. The company cautions readers that forward-looking statements, including without limitation those relating to the company’s future operations and business prospects, are subject to certain risks and uncertainties that could cause actual results to differ materially from those indicated in the forward- looking statements. Factors that may affect future operations and business prospects include, but are not limited to, clinical and scientific results and developments concerning corporate collaborations and the company’s proprietary rights and other factors described in the prospectus relating to the company’s recent public offering. For further information, please contact: Dave Lemus; Chief Financial Officer Lisa Richert; Head of PR Tel: +49 (0) 89 / 899 27-439 Tel.: +49 (0) 89 / 899 27-122 Fax: +49 (0) 89 / 899 27-5309 Fax: +49 (0) 89 / 899 27-5122 [email protected] [email protected] www.morphosys.com www.morphosys.com Eva Grabner, IR & Corp. Com. Specialist Ernie Knewitz, Vice President Tel: +49 (0) 89 / 8565-2693 Tel.: +1 (212) 696 4455 ext. 204 Fax: +49 (0) 89 / 8565-2610 Fax: +1 (212) 696 9463 [email protected] [email protected] .
Load more

Recommended publications
  • Retirement Strategy Fund 2060 Description Plan 3S DCP & JRA
    Retirement Strategy Fund 2060 June 30, 2020 Note: Numbers may not always add up due to rounding. % Invested For Each Plan Description Plan 3s DCP & JRA ACTIVIA PROPERTIES INC REIT 0.0137% 0.0137% AEON REIT INVESTMENT CORP REIT 0.0195% 0.0195% ALEXANDER + BALDWIN INC REIT 0.0118% 0.0118% ALEXANDRIA REAL ESTATE EQUIT REIT USD.01 0.0585% 0.0585% ALLIANCEBERNSTEIN GOVT STIF SSC FUND 64BA AGIS 587 0.0329% 0.0329% ALLIED PROPERTIES REAL ESTAT REIT 0.0219% 0.0219% AMERICAN CAMPUS COMMUNITIES REIT USD.01 0.0277% 0.0277% AMERICAN HOMES 4 RENT A REIT USD.01 0.0396% 0.0396% AMERICOLD REALTY TRUST REIT USD.01 0.0427% 0.0427% ARMADA HOFFLER PROPERTIES IN REIT USD.01 0.0124% 0.0124% AROUNDTOWN SA COMMON STOCK EUR.01 0.0248% 0.0248% ASSURA PLC REIT GBP.1 0.0319% 0.0319% AUSTRALIAN DOLLAR 0.0061% 0.0061% AZRIELI GROUP LTD COMMON STOCK ILS.1 0.0101% 0.0101% BLUEROCK RESIDENTIAL GROWTH REIT USD.01 0.0102% 0.0102% BOSTON PROPERTIES INC REIT USD.01 0.0580% 0.0580% BRAZILIAN REAL 0.0000% 0.0000% BRIXMOR PROPERTY GROUP INC REIT USD.01 0.0418% 0.0418% CA IMMOBILIEN ANLAGEN AG COMMON STOCK 0.0191% 0.0191% CAMDEN PROPERTY TRUST REIT USD.01 0.0394% 0.0394% CANADIAN DOLLAR 0.0005% 0.0005% CAPITALAND COMMERCIAL TRUST REIT 0.0228% 0.0228% CIFI HOLDINGS GROUP CO LTD COMMON STOCK HKD.1 0.0105% 0.0105% CITY DEVELOPMENTS LTD COMMON STOCK 0.0129% 0.0129% CK ASSET HOLDINGS LTD COMMON STOCK HKD1.0 0.0378% 0.0378% COMFORIA RESIDENTIAL REIT IN REIT 0.0328% 0.0328% COUSINS PROPERTIES INC REIT USD1.0 0.0403% 0.0403% CUBESMART REIT USD.01 0.0359% 0.0359% DAIWA OFFICE INVESTMENT
    [Show full text]
  • MDAX—2019 Supervisory Board Study Key Insights from This Year’S Analysis by Russell Reynolds Associates
    MDAX—2019 Supervisory Board Study Key insights from this year’s analysis by Russell Reynolds Associates Summary Over the past year, Germany's MDAX companies have experienced significant change. The number of companies in the index increased by 10, bringing the overall total to 60. Moreover, 11 "old economy" firms, including Jungheinrich, Krones, Leoni, Salzgitter and Schaeffler, were ousted by pharma, med and biotech risers, such as Evotec, Morphosys, Qiagen, Sartorius and Siemens Healthineers, as well as "new economy" powerhouses like Dialog, Nemetschek, Software AG, Telefonica D, and United Internet. This was also an exceptional election year, with 106 shareholder representative positions expiring. All positions were filled. A total of 67 board members were re-elected, while 36 were replaced. The three remaining roles were absorbed by changes to board sizes. Female shareholder representation surpasses 30 percent For the first time, the share of female shareholder representatives surpassed the required quota, reaching 30.6 percent. Including employee representatives, women now make up 32 percent of supervisory board members. A total of three boards are now chaired by women. However, there is still a major gender discrepancy concerning positions of power when comparing chairpersonships and especially executive board positions. Only four companies can boast more than 30 percent of female executives, while 40 MDAX companies do not have a single woman in a leadership role. Accelerated increase in digital directors The number of digital directors on MDAX supervisory boards showed a significant 30 percent year- on-year increase. However, digital expertise is still unevenly spread in the MDAX. Seven companies have three or more digital directors, while 57 percent of boards completely lack digital expertise.
    [Show full text]
  • Analyst's Conferences Tuesday, November 25, 2014
    Analyst's conferences Tuesday, November 25, 2014 Room London Sector Pharma / Biotech Time Company name Speaker 09:30-10:00 aap Implantate AG Bruke Seyoum Alemu, Chairman of the Management Board/CEO Marek Hahn, Member of the Management Board/CFO Sector Pharma / Biotech Time Company name Speaker 11:00-11:30 Eckert & Ziegler AG* Dr. Andreas Eckert, CEO Ron Littmann, CFO Sector Pharma / Biotech Time Company name Speakers 13:00-13:30 4SC AG Dipl. Kfm. Enno Spillner, CEO & CFO Jochen Orlowski, Head of Corporate Communications & Investor Relations 13:30-14:00 MorphoSys AG* Jens Holstein, Chief Financial Officer 14:00-14:30 Affimed N.V.* Dr. Adi Hoess, CEO Dr. Florian Fischer, CFO 14:30-15:00 PAION AG Dr Wolfgang Söhngen, CEO Abdelghani Omari, CFO 15:00-15:30 SYGNIS AG Pilar de la Huerta, CEO/CFO Michael Wolf, Vice President Finance & Accounting 15:30-16:00 Evotec AG Dr Werner Lanthaler, CEO 16:00-16:30 TRANSGENE Dr Hemanshu Shah, Vice President Medical Affairs PhD Elisabetta Castelli, Director Investor Relations 16:30-17:00 MOLOGEN AG Dr. Matthias Schroff, CEO 17:00-17:30 Medigene AG Peter Llewellyn-Davies, CFO 18:00-18:30 Santhera Pharmaceuticals Holding Ltd.* PhD Thomas Meier, CEO Dr. Roland Grimm, VP - Finance 18:30-19:00 Vita 34 AG* Dr. André Gerth, CEO Vita 34 Room Madrid Sector DAX / MDAX Time Company name Speakers 11:00-11:30 FUCHS PETROLUB SE Dr. Alexander Selent, Vice Chairman & CFO Dagmar Steinert, Head of Investor Relations 11:30-12:00 Axel Springer SE Claudia Thomé, Co-Head of Investor Relations Daniel Fard-Yazdani, Co- Head of Investor
    [Show full text]
  • Fund Holdings
    Wilmington International Fund as of 7/31/2021 (Portfolio composition is subject to change) ISSUER NAME % OF ASSETS ISHARES MSCI CANADA ETF 3.48% TAIWAN SEMICONDUCTOR MANUFACTURING CO LTD 2.61% DREYFUS GOVT CASH MGMT-I 1.83% SAMSUNG ELECTRONICS CO LTD 1.79% SPDR S&P GLOBAL NATURAL RESOURCES ETF 1.67% MSCI INDIA FUTURE SEP21 1.58% TENCENT HOLDINGS LTD 1.39% ASML HOLDING NV 1.29% DSV PANALPINA A/S 0.99% HDFC BANK LTD 0.86% AIA GROUP LTD 0.86% ALIBABA GROUP HOLDING LTD 0.82% TECHTRONIC INDUSTRIES CO LTD 0.79% JAMES HARDIE INDUSTRIES PLC 0.78% DREYFUS GOVT CASH MGMT-I 0.75% INFINEON TECHNOLOGIES AG 0.74% SIKA AG 0.72% NOVO NORDISK A/S 0.71% BHP GROUP LTD 0.69% PARTNERS GROUP HOLDING AG 0.65% NAVER CORP 0.61% HUTCHMED CHINA LTD 0.59% LVMH MOET HENNESSY LOUIS VUITTON SE 0.59% TOYOTA MOTOR CORP 0.59% HEXAGON AB 0.57% SAP SE 0.57% SK MATERIALS CO LTD 0.55% MEDIATEK INC 0.55% ADIDAS AG 0.54% ZALANDO SE 0.54% RIO TINTO LTD 0.52% MERIDA INDUSTRY CO LTD 0.52% HITACHI LTD 0.51% CSL LTD 0.51% SONY GROUP CORP 0.50% ATLAS COPCO AB 0.49% DASSAULT SYSTEMES SE 0.49% OVERSEA-CHINESE BANKING CORP LTD 0.49% KINGSPAN GROUP PLC 0.48% L'OREAL SA 0.48% ASSA ABLOY AB 0.46% JD.COM INC 0.46% RESMED INC 0.44% COLOPLAST A/S 0.44% CRODA INTERNATIONAL PLC 0.41% AUSTRALIA & NEW ZEALAND BANKING GROUP LTD 0.41% STRAUMANN HOLDING AG 0.41% AMBU A/S 0.40% LG CHEM LTD 0.40% LVMH MOET HENNESSY LOUIS VUITTON SE 0.39% SOFTBANK GROUP CORP 0.39% NOVARTIS AG 0.38% HONDA MOTOR CO LTD 0.37% TOMRA SYSTEMS ASA 0.37% IMCD NV 0.37% HONG KONG EXCHANGES & CLEARING LTD 0.36% AGC INC 0.36% ADYEN
    [Show full text]
  • Translation of Financial Statements As of 31 December 2020 And
    Translation of Financial Statements as of 31 December 2020 and Management Report Evotec SE Exhibit 1 Evotec SE, Hamburg Statement of financial position as of 31 December 2020 Assets 31.12.2020 31.12.2019 Equity and liabilities 31.12.2020 31.12.2019 EUR EUR EUR EUR A. Equity A. Fixed assets I. Subscribed capital 163.914.741,00 150.902.578,00 I. Intangible assets ./. nominal value Treasury shares -249.915,00 -249.915,00 Purchased franchises, industrial and similar rights 163.664.826,00 150.652.663,00 and assets, and licenses in such rights and assets 1.194.857,45 4.082.552,01 II. Capital reserves 482.139.820,51 243.587.164,27 II. Property, plant and equipment III. Reserve for treasury shares 249.915,00 249.915,00 1. Land, land rights and buildings, including buildings on third-party land 1.572.345,71 1.804.727,38 IV. Accumulated loss -100.132.424,27 -75.948.394,50 2. Plant and machinery 12.251.848,90 11.732.420,10 3. Other equipment, furniture and fixtures 1.160.417,33 1.035.981,29 545.922.137,24 318.541.347,77 4. Prepayments and assets under construction 1.315.392,83 1.118.311,65 16.300.004,77 15.691.440,42 III. Financial assets B. Provisions 1. Shares in affiliates 334.222.810,07 334.187.810,07 1. Provisions for pensions and similar obligations 169.091,00 166.780,00 2. Loans to affiliates 132.335.498,54 2.
    [Show full text]
  • Turquoise Liquidity Provision Scheme Registrations
    Turquoise Liquidity Provision Scheme Registrations Updated: 25/06/2015 Symbol Name Schedule A Schedule B A2Am A2A SPA BNP Paribas Arbitrage Société Générale SA Virtu Financial Ireland Ltd Citadel Securities (Europe) Ltd AALBa AALBERTS INDUSTRIES NV Virtu Financial Ireland Ltd AALl ANGLO AMERICAN PLC Virtu Financial Ireland Ltd ABBNz ABB LTD-REG Société Générale SA Virtu Financial Ireland Ltd ABEe ABERTIS Société Générale SA INFRAESTRUCTURAS SA Virtu Financial Ireland Ltd ABFl ASSOCIATED BRITISH Virtu Financial Ireland Ltd FOODS PLC ABGe ABENGOA SA Virtu Financial Ireland Ltd ABIb ANHEUSER-BUSCH INBEV BNP Paribas Arbitrage Société Générale SA NV Virtu Financial Ireland Ltd ACAp CREDIT AGRICOLE SA BNP Paribas Arbitrage BNP Paribas Arbitrage Société Générale SA Virtu Financial Ireland Ltd Citadel Securities (Europe) Ltd ACKBb ACKERMANS & VAN HAAREN Virtu Financial Ireland Ltd ACp ACCOR SA BNP Paribas Arbitrage Société Générale SA Virtu Financial Ireland Ltd Citadel Securities (Europe) Ltd ACSe ACS ACTIVIDADES CONS Y Société Générale SA SERV Virtu Financial Ireland Ltd ACXe ACERINOX SA Virtu Financial Ireland Ltd ADENz ADECCO SA-REG Société Générale SA Virtu Financial Ireland Ltd ADMl ADMIRAL GROUP PLC Virtu Financial Ireland Ltd ADNl ABERDEEN ASSET MGMT Virtu Financial Ireland Ltd Symbol Name Schedule A Schedule B PLC ADPp ADP BNP Paribas Arbitrage Société Générale SA Virtu Financial Ireland Ltd Citadel Securities (Europe) Ltd ADSd ADIDAS AG Société Générale SA Virtu Financial Ireland Ltd AFp AIR FRANCE-KLM BNP Paribas Arbitrage Virtu Financial
    [Show full text]
  • BAILLIE GIFFORD FUNDS Form NPORT-P Filed 2021-05-24
    SECURITIES AND EXCHANGE COMMISSION FORM NPORT-P Filing Date: 2021-05-24 | Period of Report: 2021-03-31 SEC Accession No. 0001752724-21-108126 (HTML Version on secdatabase.com) FILER BAILLIE GIFFORD FUNDS Mailing Address Business Address CALTON SQUARE, 1 CALTON SQUARE, 1 CIK:1120543| IRS No.: 000000000 | State of Incorp.:MA | Fiscal Year End: 1231 GREENSIDE ROW GREENSIDE ROW Type: NPORT-P | Act: 40 | File No.: 811-10145 | Film No.: 21954895 EDINBURGH SCOTLAND EDINBURGH SCOTLAND EH1 3AN X0 00000 EH1 3AN X0 00000 0144131222 Copyright © 2021 www.secdatabase.com. All Rights Reserved. Please Consider the Environment Before Printing This Document Portfolio of Investments March 31, 2021 (unaudited) Baillie Gifford International Growth Fund Shares Value COMMON STOCKS — 97.7% ARGENTINA — 5.0% MercadoLibre, Inc.* 139,989 $ 206,083,406 AUSTRALIA — 1.7% Afterpay Ltd.* 526,706 41,137,890 WiseTech Global Ltd. 1,309,250 29,133,261 70,271,151 BELGIUM — 1.9% Umicore SA 1,462,889 77,612,754 CHINA — 19.0% Alibaba Group Holding Ltd.* 5,696,608 161,855,593 Meituan, Class B * 5,120,500 199,823,397 NIO, Inc. ADR* 1,866,744 72,765,681 Ping An Insurance Group Co. of China Ltd., Class H 5,283,500 63,197,826 TAL Education Group ADR* 1,115,272 60,057,397 Tencent Holdings Ltd. 2,863,200 228,504,992 786,204,886 DENMARK — 5.5% Ambu A/S, B Shares 1,407,401 66,095,227 Chr. Hansen Holding A/S* 281,331 25,554,596 Genmab A/S* 289,743 95,294,646 Novozymes A/S, B Shares 384,557 24,606,538 Vestas Wind Systems A/S 85,444 17,625,973 229,176,980 FRANCE — 6.2% Adevinta ASA* 626,550 9,231,847 Faurecia SE* 34,742 1,854,525 Kering 227,284 156,839,084 L’Oreal SA 226,761 86,867,892 254,793,348 GERMANY — 7.5% Aixtron SE* 1,145,970 26,047,485 BASF SE 369,230 30,684,112 CureVac NV* 233,787 21,382,159 HelloFresh SE* 1,016,019 75,701,433 MorphoSys AG* 162,909 14,190,328 Zalando SE* 1,428,722 139,997,017 308,002,534 HONG KONG — 3.1% AIA Group Ltd.
    [Show full text]
  • FACTSHEET - AS of 28-Sep-2021 Solactive Mittelstand & Midcap Deutschland Index (TRN)
    FACTSHEET - AS OF 28-Sep-2021 Solactive Mittelstand & MidCap Deutschland Index (TRN) DESCRIPTION The Index reflects the net total return performance of 70 medium/smaller capitalisation companies incorporated in Germany. Weights are based on free float market capitalisation and are increased if significant holdings in a company can be attributed to currentmgmtor company founders. HISTORICAL PERFORMANCE 350 300 250 200 150 100 50 Jan-2010 Jan-2012 Jan-2014 Jan-2016 Jan-2018 Jan-2020 Jan-2022 Solactive Mittelstand & MidCap Deutschland Index (TRN) CHARACTERISTICS ISIN / WKN DE000SLA1MN9 / SLA1MN Base Value / Base Date 100 Points / 19.09.2008 Bloomberg / Reuters MTTLSTRN Index / .MTTLSTRN Last Price 342.52 Index Calculator Solactive AG Dividends Included (Performance Index) Index Type Equity Calculation 08:00am to 06:00pm (CET), every 15 seconds Index Currency EUR History Available daily back to 19.09.2008 Index Members 70 FACTSHEET - AS OF 28-Sep-2021 Solactive Mittelstand & MidCap Deutschland Index (TRN) STATISTICS 30D 90D 180D 360D YTD Since Inception Performance -3.69% 3.12% 7.26% 27.72% 12.73% 242.52% Performance (p.a.) - - - - - 9.91% Volatility (p.a.) 13.05% 12.12% 12.48% 13.60% 12.90% 21.43% High 357.49 357.49 357.49 357.49 357.49 357.49 Low 342.52 329.86 315.93 251.01 305.77 52.12 Sharpe Ratio -2.77 1.14 1.27 2.11 1.40 0.49 Max. Drawdown -4.19% -4.19% -4.19% -9.62% -5.56% -47.88% VaR 95 \ 99 -21.5% \ -35.8% -34.5% \ -64.0% CVaR 95 \ 99 -31.5% \ -46.8% -53.5% \ -89.0% COMPOSITION BY CURRENCIES COMPOSITION BY COUNTRIES EUR 100.0% DE
    [Show full text]
  • Evotec OAI AG Annual Report 2004 'Taking the Lead'
    Evotec OAI AG Annual Report 2004 ‘taking the lead’ Segment overview Evotec OAI operates through three Discovery Programs business divisions: Division (DPD) > Discovery Programs Division: Evotec OAI’s Discovery Programs Division proprietary drug candidates (DPD) is developing a deep portfolio of > Discovery and Development proprietary drug candidates. With years Services: contract research and of experience in assay development, development screening, chemistry and optimisation, > Tools and Technologies|Evotec Evotec OAI has established a strong Technologies: technologies and track record of successfully identifying instruments such candidates for its customers. In its proprietary research DPD has built up extensive knowledge about diseas- es of the central nervous system (CNS) through Evotec Neurosciences (ENS) and about metabolic disorders through the joint venture with DeveloGen. Through the acquisition of full ownership interest in ENS in March 2005, the Com- pany has now established its own attrac- tive CNS pipeline. DPD plans to rapidly progress the current programmes, to ex- pand these activities and to engage in early partnerships and|or out-license the drugs at proof-of-concept to the pharma- ceutical industry which is continuously searching for novel drug candidates to fill their clinical development pipelines. Discovery and Development Tools and Technologies Services (DDS) (Evotec Technologies|ET) Evotec OAI’s Discovery and Development Evotec Technologies (ET) is developing Services (DDS) division provides drug innovative drug discovery technolo- discovery contract research and develop- gies and instruments for the pharmaceu- ment support to a large group of global tical and biotechnology industries customers and to Evotec OAI’s internal and academic research institutions. The research in the Discovery Programs Company provides cutting-edge solu- Division.
    [Show full text]
  • Small and Mid Cap German CS
    January 31, 2020 Luxembourg Risk profile (SRRI) 1) 1 2 3 4 5 6 7 CS (Lux) Small and Mid Cap Germany Equity Fund a subfund of CS Investment Funds 2 - Class B EUR Investment policy Net performance in EUR (rebased to 100) and yearly performance 2) The aim of the Fund is to achieve the highest possi- 200 100% ble capital growth. Investment focus is on small and 180 80% mid-sized companies domiciled in Germany. Small 160 60% and mid sized companies are companies not being 140 30.2 30.6 40% part of the DAX 30 Index. 25.7 23.0 27.3 120 19.5 20% 4.7 100 0.5 0% Fund facts -1.7 -1.2 80 -13.2 -13.7 -20% Fund manager Felix Meier 60 -40% Fund manager since 01/01/2003 2015 2016 2017 2018 2019 2020 Location Zurich CS (Lux) Small and Mid Cap Germany Equity Fund Yearly or year-to-date performance respectively Management Credit Suisse Fund Management B EUR (Fund) company S.A. Yearly or year-to-date performance respectively MDAX (NR) (10/18) Fund domicile Luxembourg (Benchmark) Fund currency EUR Close of financial year 31. Mar Net performance in EUR 2) Total net assets (in millions) 307.30 1 month 3 months YTD 1 year 3 years 5 years Inception date 26/08/1994 Fund -1.73 5.77 -1.73 13.66 38.96 59.04 Management fee in % p.a. 1.60 Benchmark -1.16 6.61 -1.16 17.67 35.46 64.49 TER (as of 31.03.2019) in % 1.85 Benchmark (BM) MDAX (NR) (10/18) Swinging single pricing (SSP) 3) Yes Sectors in % Fund Unit Class Category B Industrials 23.76 (capital growth) Health Care 17.89 Unit class currency EUR Information Technology 11.48 ISIN number LU0052265898 Consumer Discretionary 10.33 Bloomberg ticker CRSESGI LX Materials 9.80 Net Asset Value 3,021.44 Communication Services 8.34 Redemptions Daily Financials 7.22 Real Estate 6.70 Morningstar Rating as of 31/01/2020 Cash/Cash Equivalents 0.48 3) For more details, please refer to the relevant Others 4.01 chapter "Net Asset Value" of the Fund’s prospectus.
    [Show full text]
  • Evotec Kauft US-Firma Für 256 Mio. Euro
    Interview Cellact-Chefin Nalân Utku über den erfolgreichen Verkauf ihrer virtuellen Firma an Mundi- Wirtschaft. Technologie. Leben. 23. Jahrgang. 9|2017. pharma ISSN 1435-5272 | A 49017 25 JAHRE Morphosys feiert doppelt LESEPROBE DIGITALE MEDIZIN Deutschland will aufholen Expansion SPEZIAL Biosimilars drängen in Markt Evotec kauft US-Firma WAHL 2017 für 256 Mio. Euro Biopolitik in den Wahlprogrammen Bei Amgen sind biologische Arzneimittel in Qualität verwurzelt und werden von Zuverlässigkeit genährt. Eine solide Qualitätskontrolle und zuverlässige Versorgung sind genau so wichtig wie wissenschaftliche Innovationen. Seit mehr als drei Jahrzehnten wird bei Amgen jedes Medikament mit Engagement, Leidenschaft und dem Streben nach Perfektion hergestellt. Darum finden Sie bei Amgen die Biologika, die für die Behandlung Ihrer Patienten so enorm wichtig sind. Und das auch für die zukünftigen Generationen. Weitere Informationen über Amgens Engagement für eine gleichbleibende 8\HSP[p[\UKa\]LYSpZZPNL=LYZVYN\UNÄUKLU:PL\U[LY biotechnologybyamgen.de ©2013 Amgen Inc. Alle Rechte vorbehalten. AMG-DEU-AMG-021-2014-January-P (1/2014) 02_tk12_15_Amgen.indd 2 02.12.2015 15:22:22 Uhr European Biotechnology NETWORK Bundestagswahl I Stellt Euch vor, es ist Wahlkampf, und keiner kriegt‘s mit. Bis zum Redaktionsschluss jedenfalls konnte von Kampf um Wählerstimmen in Deutschland keine Rede sein. Die Regierende gibt wie üblich das Präsidenten-Surrogat, während es dem herausfordernden Dampfplauderer noch nicht einmal gelingt, aus dem Schatten seiner ver- staubten Partei zu treten. Die Grünen haben ein ernstes Verkalkungsproblem, die Populisten vom rechten und linken Rand verkünden ihr übliches dummes Zeug. Bei der FDP lässt sich noch nicht sagen, ob sie sich im Par- lament trauen wird, die von vielen vermisste Stimme der Andreas Mietzsch wirtschaftlichen Sachkenntnis und Vernunft zu erheben.
    [Show full text]
  • Authorizations for Capital Raisings and Convertible Bond Issues
    Authorizations for Capital Raisings, Convertible Bond Issues and Share Repurchases (2019) German DAX® and MDAX® Companies clearygottlieb.com Preface This booklet presents a summary overview of authorizations for capital raisings and convertible bond issuances of all German DAX® and MDAX® companies based on their 2019 annual general meetings.* Responding to inquiries from clients and friends, this booklet now also covers authorizations for share repurchases of all German DAX® and MDAX® companies, also based on their 2019 annual general meetings. The amount of any authorized capital reflected in this booklet takes into account any issuance of shares out of authorized capital entered into the commercial register prior to August 1, 2019. The amount of any convertible bond authorization and underlying conditional capital reflected in this booklet takes into account the issuance of any convertible bonds based on such authorization prior to August 1, 2019 and the amount of conditional capital underlying such convertible bonds. The number of any shares repurchased under a buy-back program reflected in this booklet takes into account the publicly announced share repurchases of the respective issuer until August 1, 2019. Consistent with the nature of the booklet as a summary overview, the information on the authorizations for capital raisings, convertible bond issuances and share repurchases provided herein is limited to the key parameters of the relevant authorized capital, convertible bond authorization, conditional capital and share repurchase authorization. A more detailed analysis of, e.g., the feasibility of a certain capital raising or share repurchase will always require a comprehensive review of the complete wording of the authorization(s) concerned.
    [Show full text]