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Poison Or Antibiotic? a Guide to "Class" Entries

Poison Or Antibiotic? a Guide to "Class" Entries

Poison or ? A Guide to “Class” Entries

Preface

Most entries in the Poisons List and the First, Second and Third Schedules to the Pharmacy and Poisons Regulations are in the form of individual and their salts, e.g. “Abacavir; its salts”.

However, some entries are in the form of a “class”, e.g. “Barbituric acid; its salts; its derivatives …”. In such cases, it is not always clear which drugs are members of the class (e.g. amobarbital, barbital, pentobarbital, phenobarbital, etc. are poisons, being derivatives of barbituric acid).

Likewise, the Ordinance applies to the substances specified in Schedule 1 to the Antibiotics Regulations, to their salts and derivatives, and to the salts of such derivatives. Again, it is not always clear which drugs are derivatives of an antibiotic named in the Schedule (e.g. demeclocycline, doxycycline, tigecycline, etc. are antibiotics, being derivatives of “Tetracycline” named in the Schedule).

This Guide provides a list of such drugs which are available as registered pharmaceutical products in .

Drugs which are not available as registered pharmaceutical products in Hong Kong are also included in this Guide as far as possible. It should be noted that it is not possible to compile a complete list of all these drugs, simply because there is no limit to the number of “derivatives” a parent chemical can have.

This Guide should be read in conjunction with the Poisons List, the First, Second and Third Schedules to the Pharmacy and Poisons Regulations, and Schedule 1 to the Antibiotics Regulations, if the poison/antibiotic classification of a particular pharmaceutical product is to be determined.

Pharmaceutical Service Department of Health September 2007

Step-by-step guidance on determining the poison/antibiotic classification of a pharmaceutical product

1. Identify the (first) contained in the pharmaceutical product.

2. If this drug is found in the Poisons List, continue to look for it in the First and Third Schedules to the Pharmacy and Poisons Regulations to determine the “poison” classification of the pharmaceutical product containing this drug. Then look for it in the Second Schedule to determine if the product is exempted from control as poison under that Schedule.

3. If the drug is not found in the Poisons List, look for it in Schedule 1 to the Antibiotics Regulations.

4. If the drug is found in Schedule 1, the pharmaceutical product will be an antibiotic.

5. If the drug is found neither in the Poisons List nor in Schedule 1 to the Antibiotics Regulations, look for it in the Index to the Guide.

6. If the drug is found in the Index to the Guide, note the Item Number against it, then turn to the Guide itself to identify the Item number and the corresponding Entry in the Poisons List or Antibiotics Schedule of the drug.

7. Repeat steps 2 to 5 with respect to this entry, to determine the classification of the pharmaceutical product containing this drug.

8. If the drug is not found in the Index to the Guide, look for its synonyms (in “Martindale”, the Merck Index, etc), and repeat steps 2 to 7 with respect to each synonym.

9. If none of the synonyms is found in the Index to the Guide after repeating steps 2 to 7, the pharmaceutical product containing the drug will be neither a poison nor an antibiotic.

10. For a multi-component product, repeat the above steps with respect to each component. The “poison” classification of the product itself will be that of the most stringently classified component. In addition, if one component is classified as antibiotic, the product itself will also be classified as an antibiotic.

Index to the Guide

Drug Name Item Amoxicillin 105 No. Ampicillin 105 Acepromazine 108 Amylobarbitone 36 Acetarsol 33 Amylocaine 24 108 29 Acetoxypregnenolone 126 29 Acetyl sulfamethoxypyrazine 25 Antihaemophilic factor 41 Acetyldigitoxin 63 Antimony potassium tartrate 32 Acetyldigoxin 63 Antimony sodium gluconate 32 Acetyldihydrocodeinone 65 Aprobarbital 36 Acetylkitasamycin 48 Arbekacin 87 Aconitine 5 Arbutamine 126 Adefovir dipivoxil 2 Arsanilic acid 33 Adiphenine 24 Arsenamide 33 Adrenaline 126 33 Ajmaline 19 Arsthinol 33 131 L- 58 Alclofenac monoethanolamine 4 methobromide 6 126 Atropine methonitrate 6 126 Azaribine 34 126 31 29 Azathioprine 90 Allobarbital 36 Azidamphenicol 51 Allyloestrenol 29 Azithromycin 69 Alphadolone acetate 23 Azosemide 55 Alprazolam 61 Aztreonam 105 Althiazide 53 Bacampicillin 105 29 31 77 Barbital 36 Ambucaine 24 Barbitone 36 126 Beclomethasone 126 Amethocaine 24 Bekanamycin 87 Amfepramone 96 99 Amikacin 87 Bendrofluazide 53 Aminosalicylate 28 Bendroflumethiazide 53 p-Aminosalicylic acid hydrazide 28 Benfluorex 96 119 Benmoxine 78 Amobarbital 36 Benoxinate 24 Amodiaquin 52 Benperidol 76 Benzathine Benzylpenicillin 105 Carbarsone 33 29 Carbenicillin 105 Benzocaine 26 Carbetocin 104 Benzodepa 35 31 Benzoylpas 28 Carbocloral 50 Benzphetamine 96 Carboprost 118 Benzthiazide 53 35 Benzylhydrochlorothiazide 53 Carfecillin 105 Benzylpenicillin 105 Cargutocin 104 Benzylsulfamide 25 Carindacillin 105 31 71 126 Carphenazine 108 29 Cathine 11 Brallobarbital 36 Cefaclor 49 Bromazepam 61 Cefadroxil 49 Bromperidol 76 Cefalexin 49 31 Cefaloridine 49 Bromvalerylurea 42 Cefalotin 49 29 Cefamandole 49 126 Cefapirin 49 Bufotenine 81 Cefatrizine 49 Butabarbital 36 Cefazedone 49 Butacaine 26 Cefcapene 49 Butalbital 36 Cefdinir 49 Butamben 26 Cefditoren 49 108 Cefepime 49 Butethamate 24 Cefetamet 49 Butethamine 26 Cefixime 49 Buthiazide 53 Cefmenoxime 49 Butobarbital 36 Cefminox 49 Butoxycaine 24 Cefodizime 49 119 Cefonicid 49 Butropium 15 Cefoperazone 49 Butyl aminobenzoate 26 Ceforanide 49 Cacodylate 33 Cefoselis 49 Cafedrine 96 Cefotaxime 49 Calcitonin 129 Cefotiam 49 Camazepam 61 Cefpimizole 49 Candesartan cilexetil 45 Cefpiramide 49 Canfosfamide 99 Cefpirome 49 Cannabidiol 47 Cefpodoxime 49 Cefprozil 49 54 Cefradine 49 126 Cefroxadine 49 Cloprostenol 118 Cefsulodin 49 Clorazepate 61 Ceftazidime 49 29 Ceftibuten 49 Cloxacillin 105 Ceftiofur 49 Cloxazolam 61 Ceftizoxime 49 29 Ceftriaxone 49 61 Chloral betaine 50 Cocaethylene 10 Chloral hydrate 50 Codoxime 64 Alpha-Chloralose 50 Colchicine 8 99 Colistimethate sodium 59 Chloraminophenamide 55 Colpormon 29 acetate 29 Combelen 108 Chlornaphazine 99 126 126 126 Chloroprocaine 24 Crotarbital 36 30 Cyacetacide 79 30 108 29 Cyclobarbital 36 Chlorphenamide 55 Cyclodrine 24 Chlorpheniramine 31 Cyclomethycaine 24 108 Cyclopenthiazide 53 theophyllinate 128 Cyclopentobarbital 36 126 24 14 99 Cinchocaine 80 Cyclothiazide 53 Cinchophen 110 Cymarin 124 31 31 Clarithromycin 69 29 31 Dalfopristin 115 31 29 Clindamycin 88 Deanol Benzilate 24 126 Decamethonium bromide 114 126 126 Clocapramine 57 Defosfamide 99 Clocinizine 31 Delorazepam 61 126 Demeclocycline 127 Clonazepam 61 29 Clopamide 55 Demoxytocin 104 Denopterin 27 Dimethylaminoethyl 19 Deoxycorticosterone 126 Reserpilinate Deprenyl 96 Dimethylthiambutene 68 31 31 Deserpidine 19 Dimetofrine 126 Deslanoside 63 31 Desmopressin 135 Dipivefrin 126 29 Dipyrone 101 126 Dirithromycin 69 Desoxymethasone 126 Divalproex sodium 133 126 108 31 71 31 3 Dextromethorphan 92 Doxycycline 127 Dextropropoxyphene 116 Drosprienone 29 Dextrorphan 82 29 Diacetyldihydromorphine 66 29 Diacetylmorphine 17 Eburnamonine 21 Diaziquone 35 Elcatonin 129 Dibekacin 87 31 Dichloralphenazone 50 31 126 Enprostil 118 Dichlorphenamide 55 Ephedrine 11 Dicloxacillin 105 Epicillin 105 Dienoestrol 29 29 29 31 Diethylpropion 96 Epinephrine 126 29 3 Diethylthiambutene 68 29 126 Epoetin alfa 120 126 Eptacog alfa (activated) 41 126 29 Digitalin 63 Ergocornine 12 63 Ergocristine 12 Digoxin 63 Ergocryptine 12 Dihydrostreptomycin 123 Ergometrine 12 Diisopropanolamine felbinac 38 Ergotamine 12 30 Ergotoxine 12 29 Ertapenem 105 Dimethocaine 26 Escitalopram 56 Eseridine salicylate 7 Estazolam 61 Flunitrazepam 61 29 butyl 126 99 126 29 126 29 29 29 acetate 126 29 108 Ethinyloestradiol 29 acetate 126 29 126 Ethotoin 111 Flurandrenolide 126 Ethybenztropine 37 Flurazepam 61 Ethyl loflazepate 61 Flurogestone acetate 29 Ethylamphetamine 96 126 Ethylmethylthiambutene 68 Flutoprazepam 61 Ethyloestrenol 29 Fluzacort 126 Ethynodiol 29 Follicle-stimulating 112 dicloacetate 126 Follitropin 112 Etofenamate 70 Follitropin alfa 112 29 Follitropin beta 112 Factor IX (recombinant) 41 29 Factor VIIa (recombinant) 41 126 Factor VIII 41 Formosulfathiazole 25 Factor VIII (recombinant) 41 Formylsulfamethine 25 Factor VIII (recombinant) 41 29 Felbinac 38 FSH 112 Felypressin 135 29 Fenethylline 96 Fusidates 73 Fenproporex 96 Gallamine triethiodide 74 Fenprostalene 118 Gelsemine 13 Fentonium bromide 15 Gemeprost 118 71 Gepefrine 96 Flucinolone 126 29 Flucinonide 126 29 Flucloronide 126 29 Flucloxacillin 105 Gitoxin 63 Fludiazepam 61 Glyceryl p-aminobenzoate 26 126 Glyconiazide 86 Flumethasone 126 Gramicidin 132 Flumethiazide 53 Halazepam 61 31 126 126 Halobetasol 126 126 30 acetate 126 Levodopa 67 Haloxazolam 61 102 Heptabarbital 36 29 Hexamethonium 114 Levophenacylmorphan 84 Hexobarbital 36 Levorphanol 82 Hexoestrol 29 LH 112 Hexoprenaline 126 Limaprost 118 Hexylcaine 24 Liothyronine 129 30 Lobeline 16 31 57 Homofenazine 108 Loprazolam 61 Human growth hormone 112 Lorazepam 61 Hydrargaphen 91 Lormetazepam 61 Hydrochlorothiazide 53 etabonate 126 126 112 126 Lutropin alfa 112 Hydroflumethiazide 53 Lymecycline 127 Hydroxychloroquine 52 Lynoestrenol 29 Hydroxyprogesterone 29 Lypressin 135 Hydroxytetracaine 24 126 Hyoscine-N-butyl bromide 14 96 60 Mecillinam 105 Imipenem 105 Meclocycline 127 Indapamide 55 Medazepam 61 Ipratropium 6 29 Iproniazid 86 29 Isepamicin 75 126 Isobutyl p-aminobenzoate 26 29 Isocarboxazid 78 Meglumine antimonate 32 126 Melarsoprol 33 Isoproterenol 126 76 Ketazolam 61 99 Kitasamycin 48 112 Lanatosides 63 Meparfynol 95 Latamoxef 49 Mephentermine 96 Leucomycin 48 Mephenytoin 111 Leucovorin 72 29 Levobunolol 117 126 Levobupivacaine 44 30 31 108 Merbromin 91 Morphine methobromide 17 Mercurochrome 91 57 108 Moxalactam 49 29 29 29 Moxidectin 98 Metaclazepam 61 Mycophenolate mofetil 100 Metampicillin 105 Nadoxolol 117 Methacycline 127 Naftopidil 117 Methamphetamine 96 29 29 Neoarsphenamine 33 Methandrostenolone 29 Netilmicin 75 Methanearsonic acid 33 Nicomorphine 17 Methaniazide 86 Nimetazepam 61 30 Nitrazepam 61 Methenolone 29 Nitropentaerythritol 106 Methetoin 111 acetate 29 Methicillin sodium 105 Nonacog alfa 41 Methisopurinol 85 Noprylsulfamide 25 Methohexital 36 Noradrenaline 126 27 Nordazepam 61 Methotrimeprazine 108 Nordefrin 126 Methscopolamine bromide 14 29 Methyclothiazide 53 29 N-Methylacetanilide 1 29 Methyladrenaline 126 Norethynodrel 29 N-Methylephedrine 11 29 Methylphenobarbital 36 29 3-Methyl-5-phenylhydantoin 111 29 126 29 29 Norlevorphanol 83 Metocurine 9 29 Meturedepa 35 d-Norpseudoephedrine 11 Mezlocillin 105 29 Midazolam 61 Octocog Alfa 41 Mikamycin 136 Octodrine 93 Minocycline 127 Oestrogen 29 126 31 Monomethylarsinate 33 Ornipressin 135 Moperone 76 Ornoprostil 118 Moramide intermediate 94 Otilonium 24 Moroctocog alfa 41 Ouabain 124 29 Phenoxypropazine 78 Oxacillin 105 Phentermine 96 29 Phenyl aminosalicylate 28 31 96 Oxazepam 61 31 Oxazolam 61 111 14 Phthalylsulfacetamide 25 Oxophenarsine 33 Phthalylsulfathiazole 25 Oxophenylarsine 33 Physostigmine 7 Oxybuprocaine 24 18 24 Pimozide 39 Oxycinchophen 80 Pinazepam 61 29 Pipamperone 76 29 Piperacetazine 108 Parahexyl 46 Piperacillin 105 126 Pipothiazine 108 Paraoxon 62 Pipradrol 96 Parethoxycaine 24 Piprinhydrinate 31 Pasiniazide 86 Piretanide 43 39 Pivampicillin 105 Penicillin G 105 Pivmecillinam 105 Penicillin V 105 Polyestradiol 29 29 Polyestriol 29 Pentamethonium bromide 114 Polythiazide 53 Pentobarbital 36 Potassium cyanide 79 Pentorex 96 Prajmaline 19 Peplomycin 40 29 108 Prazepam 61 Perfosfamide 99 126 Pericyazine 108 99 Perimethazine 108 126 Perindopril 107 126 108 126 97 Prednival 126 Phendimetrazine 96 126 Phenelzine 78 126 Pheniprazine 78 Prenylamine 96 31 Procaine 24 Phenmetrazine 96 Procaine Penicillin 105 Phenobarbital 36 108 Phenoxymethylpenicillin 105 29 112 14 108 Secbutabarbital 36 29 Secobarbital 36 29 Selamectin 98 Propallylonal 36 Selegiline 96 Propanocaine 24 31 Proparacaine 24 Sisomicin 75 Properidine 97 Sodium cyanide 79 108 Somatotropin 112 Propionylpromazine 108 Somatrem 112 Propoxycaine 24 Somatropin 112 Prothrombin 41 Spiperone 76 Protoveratrines 20 Stanolone 29 Proxibarbal 36 29 Proxymetacaine 24 Stibocaptate 32 Pseudoephedrine 11 Stibophen 32 Psilocin 81 Strophanthin 124 Psilocybin 81 Succinylsulfathiazole 25 Pyrazinobutazone 109 Sulbenicillin 105 Pyrilamine 30 Sulfabenz 25 Quazepam 61 Sulfabenzamide 25 Quinalbarbitone 36 Sulfabromomethazine 25 29 Sulfacarbamide 25 Quinestradiol 29 25 29 Sulfachlorpyridazine 25 Quinupristin 115 Sulfachrysoidine 25 Raubasine 19 Sulfaclozine 25 Rescinnamine 19 Sulfacytine 25 Reserpine 19 25 121 25 121 25 121 25 121 25 126 Sulfaethidole 25 Rioprostil 118 25 Rolitetracycline 127 Sulfaguanidine 25 Roxarsone 33 Sulfaguanole 25 Roxithromycin 69 Sulfaloxic acid 25 Salazosulfadimidine 25 25 Salcatonin 129 25 Salinazid 86 Sulfamethomidine 25 25 29 Sulfamethoxydiazine 25 29 25 Tetracaine 24 Sulfamethylthiazole 25 Tetrahydrocannabinols 46 Sulfametopyrazine 25 Tetrazepam 61 25 Thebacon 65 Sulfamidochrysoidine 25 30 Sulfamonomethoxine 25 Thiamiprine 90 25 Thiamphenicol 51 Sulfamoylsulfanilanilide 25 Thiazinamium methylsulfate 108 25 Thiazolinobutazone 109 25 Thioguanine 90 Sulfaperine 25 Thiopentone 36 25 108 Sulfapyrazole 25 Thioproperazine 108 25 108 Sulfaquinoxaline 25 Thiothixene 54 Sulfasalazine 25 30 Sulfaside 33 Thromboplastin 41 Sulfasomizole 25 Thyroid-stimulating hormone 112 Sulfasymazine 25 Thyrotropin 112 25 Thyroxine 129 Sulfathiourea 25 Tiamulin 113 25 29 Sulfatroxazole 25 Ticarcillin 105 25 Tigecycline 127 Sulfonethylmethane 125 Tilmicosin 122 Sulfoniazide 86 Timiperone 76 108 29 Sulprostone 118 126 Sultamicillin 105 Tobramycin 75 T3 129 31 T4 129 29 Talbutal 36 126 Tamsulosin 96 Triazolam 61 Teclothiazide 53 Trichlormethiazide 53 71 Trichlormethine 99 Teicoplanin 134 Trichlorourethan 130 Telithromycin 69 Triclofos 130 Temazepam 61 Trifluomeprazine 108 Terlipressin 135 108 Trifluperidol 76 108 Triiodothyronine 129 24 Trimoprostil 118 Tripamide 55 Tripolidine 31 Tritoqualine 31 99 Troleandomycin 103 Tryparsamide 33 TSH 112 Tubocurarine 9 Tylosin 122 Tyrocidine 132 99 Uredepa 35 112 Valethamate 24 Valnemulin 113 133 Vinbarbital 36 21 Vincamine 21 21 Vinylbital 36 Ximelagatran 89 Xipamide 55 Yohimbine 22 δ-Yohimbine 19 54 The Guide

Item Entry in the Poisons List or Drugs Covered No. Antibiotics Schedule by the Entry 1. Acetanilide: alkyl acetanilides N-Methylacetanilide 2. Adefovir; its salts; its esters; their salts Adefovir dipivoxil 3. Adriamycin Doxorubicin Epirubicin 4. Alclofenac; its complexes Alclofenac monoethanolamine 5. Alkaloids: Aconite Aconitine 6. Alkaloids: Atropine Atropine methobromide Atropine methonitrate Ipratropium 7. Alkaloids: Calabar bean Eseridine salicylate Physostigmine 8. Alkaloids: Colchicum Colchicine 9. Alkaloids: Curare; curare bases Metocurine Tubocurarine 10. Alkaloids: Ecgonine; its esters and Cocaethylene 11. Alkaloids: Ephedra Ephedrine N-Methylephedrine d-Norpseudoephedrine (Cathine) Pseudoephedrine 12. Alkaloids: Ergot Ergometrine Ergotamine Ergotoxine (mixture of Ergocristine, Ergocryptine & Ergocornine) 13. Alkaloids: Gelsemium Gelsemine 14. Alkaloids: Hyoscine Cimetropium bromide Hyoscine-N-butyl bromide Methscopolamine bromide Oxitropium bromide Scopolamine 15. Alkaloids: Butropium Fentonium bromide 16. Alkaloids: Lobelia Lobeline 17. Alkaloids: Morphine; its esters and Diacetylmorphine ethers Morphine methobromide Nicomorphine 18. Alkaloids: Pilocarpus Pilocarpine 19. Alkaloids: Rauwolfia; their derivatives Ajmaline Deserpidine Dimethylaminoethyl reserpilinate Prajmaline Raubasine (δ-yohimbine) Rescinnamine Reserpine 20. Alkaloids: Veratrum Protoveratrines 21. Alkaloids: Vinca Eburnamonine Vinblastine Vincamine Vincristine 22. Alkaloids: Yohimba Yohimbine 23. Alphadolone; its esters Alphadolone acetate 24. Amino-alcohols esterified with Adiphenine benzoic acid, phenylacetic acid, Ambucaine phenylpropionic acid, cinnamic acid or Amethocaine (Tetracaine) the derivatives of these acids; their Amylocaine salts (except procaine when in a Benoxinate (Oxybuprocaine) preparation containing any substance Butethamate to which the Antibiotics Ordinance Butoxycaine (Cap. 137) for the time being applies) Chloroprocaine Cyclodrine Cyclomethycaine Cyclopentolate Deanol benzilate Hexylcaine Hydroxytetracaine Otilonium Oxybutynin Parethoxycaine Procaine Propanocaine Proparacaine (Proxymetacaine) Propoxycaine Trimebutine Valethamate 25. para-Aminobenzenesulphonamide; its Acetyl sulfamethoxypyrazine salts; derivatives of Benzylsulfamide para-aminobenzenesulphonamide Formosulfathiazole having any of the hydrogen atoms of Formylsulfamethine the para-amino group or of the Noprylsulfamide sulphonamide group substituted by Phthalylsulfacetamide another radical; their salts Phthalylsulfathiazole Salazosulfadimidine Succinylsulfathiazole Sulfabenz Sulfabenzamide Sulfabromomethazine Sulfacarbamide Sulfacetamide Sulfachlorpyridazine Sulfachrysoidine Sulfaclozine Sulfacytine Sulfadiazine Sulfadicramide Sulfadimethoxine Sulfadimidine Sulfadoxine Sulfaethidole Sulfafurazole Sulfaguanidine Sulfaguanole Sulfaloxic acid Sulfamerazine Sulfamethizole Sulfamethomidine Sulfamethoxazole Sulfamethoxydiazine Sulfamethoxypyridazine Sulfamethylthiazole Sulfametopyrazine Sulfametrole Sulfamidochrysoidine Sulfamonomethoxine Sulfamoxole Sulfamoylsulfanilanilide Sulfanilamide Sulfanitran Sulfaperine Sulfaphenazole Sulfapyrazole Sulfapyridine Sulfaquinoxaline Sulfasalazine Sulfasomizole Sulfasymazine Sulfathiazole Sulfathiourea Sulfatolamide Sulfatroxazole Sulfisomidine 26. para-Aminobenzoic acid, esters of; Benzocaine their salts Butacaine Butethamine Butyl aminobenzoate (Butamben) Dimethocaine Glyceryl p-aminobenzoate Isobutyl p-aminobenzoate 27. ; its derivatives Denopterin Methotrexate 28. Para-Aminosalicylic acid; its salts; its Aminosalicylate derivatives; their salts; any compound p-Aminosalicylic acid hydrazide with any substance falling within this Benzoylpas item Phenyl aminosalicylate 29. Androgenic, oestrogenic and Algestone acetophenide progestational substances Allyloestrenol Altrenogest Androstenediol Androstenedione Benzestrol Boldenone Broparestrol Chlorotrianisene Clostebol Cloxotestosterone Colpormon Cyproterone Danazol Demegestone Desogestrel Dienoestrol Dienogest Diethylstilbestrol Dimethisterone Drosprienone Drostanolone Dydrogesterone Epimestrol Epitiostanol Equilin Estradiol Estrapronicate Estriol Estrone Estropipate Ethinyloestradiol Ethisterone Ethyloestrenol Ethynodiol Etonogestrel Fluoxymesterone Flurogestone acetate Formebolone Fosfestrol Furazabol Gestodene Gestrinone Gestronol Hexoestrol Hydroxyprogesterone Levonorgestrel Lynoestrenol Medrogestone Medroxyprogesterone Megestrol Mepitiostane Mesterolone Mestranol Methandriol Methandrostenolone Methenolone Methyltestosterone Moxestrol Nandrolone Norelgestromin Norethandrolone Norethisterone Norethynodrel Norgesterone Norgestimate Norgestrel Norgestrienone Normethandrone Norvinisterone Oestrogen Oxabolone Oxandrolone Oxymesterone Oxymetholone Pentagestrone Polyestradiol Polyestriol Prasterone Progesterone Promegestone Promestriene Quinbolone Quinestradiol Quinestrol Stanolone Stanozolol Testolactone Testosterone Tibolone Tiomesterone Trenbolone 30. substances: those Chloropyramine included in Part I Chlorothen Dimenhydrinate Histapyrrodine Levocetirizine Mepyramine (Pyrilamine) Methapyrilene Thenyldiamine Thonzylamine 31. Antihistamine substances: those Azatadine included in Part II Bamipine Bepotastine Brompheniramine Carbinoxamine Chlorpheniramine Cinnarizine Clemastine Clemizole Clocinizine Cyproheptadine Deptropine Dexbrompheniramine Dexchlorpheniramine Dimetindene Diphenylpyraline Embramine Emedastine Epinastine Flunarizine Homochlorcyclizine Levocabastine Olopatadine Oxatomide Pheniramine Phenyltoloxamine Piprinhydrinate Setastine Tolpropamine Tripolidine Tritoqualine 32. Antimony, chlorides of; organic Antimony potassium tartrate compounds of; antimonates; Antimony sodium gluconate antimonites Meglumine antimonate Stibocaptate Stibophen 33. Arsenical substances, the following: Acetarsol halides of arsenic; organic compounds Arsanilic acid of arsenic; oxides of arsenic; sulphides Arsenamide of arsenic; arsenates; arsenites, Arsenic Trioxide thioarsenates Arsthinol Cacodylate Carbarsone Melarsoprol Methanearsonic acid Monomethylarsinate Neoarsphenamine Oxophenarsine Oxophenylarsine Roxarsone Sulfaside Tryparsamide 34. Azauridine; its derivatives Azaribine 35. ; its derivatives Benzodepa Carboquone Diaziquone Meturedepa Uredepa 36. Barbituric acid; its salts; its Allobarbital derivatives; their salts; any compound Amylobarbitone (Amobarbital) with any substance falling within this Aprobarbital item Barbital (Barbitone) Brallobarbital Butabarbital (Secbutabarbital) Butalbital Butobarbital Crotarbital Cyclobarbital Cyclopentobarbital Heptabarbital Hexobarbital Methohexital Methylphenobarbital Pentobarbital Phenobarbital Propallylonal Proxibarbal Secobarbital (Quinalbarbitone) Talbutal Thiopentone Vinbarbital Vinylbital 37. Benztropine and its homologues; their Ethybenztropine salts 38. Biphenylacetic acid; its salts; its esters Diisopropanolamine felbinac Felbinac 39. N-[4,4-Bis(para-fluorophenyl)butyl]pi Penfluridol peridine, 4-substituted derivatives of; Pimozide their salts 40. Peplomycin 41. Blood Products derived from human Antihaemophilic factor (Factor VIII) blood or manufactured by Eptacog alfa (activated) (recombinant biotechnology Factor VIIa) Moroctocog alfa (recombinant Factor VIII) Nonacog alfa (recombinant Factor IX) Octocog alfa (recombinant Factor VIII) Prothrombin Thromboplastin 42. Bromvaletone Bromvalerylurea 43. Bumetanide; its salts; its derivatives; Piretanide their salts 44. Bupivacaine; its salts Levobupivacaine 45. Candesartan; its salts; its esters; their Candesartan cilexetil salts 46. Cannabinol and its tetrahydro Parahexyl derivatives; their 3-alkyl homologues; Tetrahydrocannabinols any ester or of any substance falling within this item 47. Cannabis; the resin of cannabis; Cannabidiol extracts of cannabis; tinctures of cannabis; cannabin tannate 48. Carbomycin Acetylkitasamycin Kitasamycin (Leucomycin) 49. Cephalosporins Cefaclor Cefadroxil Cefalexin Cefaloridine Cefalotin Cefamandole Cefapirin Cefatrizine Cefazedone Cefcapene Cefdinir Cefditoren Cefepime Cefetamet Cefixime Cefmenoxime Cefminox Cefodizime Cefonicid Cefoperazone Ceforanide Cefoselis Cefotaxime Cefotiam Cefpimizole Cefpiramide Cefpirome Cefpodoxime Cefprozil Cefradine Cefroxadine Cefsulodin Ceftazidime Ceftibuten Ceftiofur Ceftizoxime Ceftriaxone Latamoxef Moxalactam 50. Chloral; its addition and its Carbocloral condensation products; any compound Chloral betaine with any substance falling within this Chloral hydrate item Alpha-Chloralose Dichloralphenazone 51. Chloramphenicol Azidamphenicol Thiamphenicol 52. Chloroquine; its salts; its derivatives; Amodiaquin their salts Hydroxychloroquine 53. Chlorothiazide and other derivatives of Althiazide benzo-1, 2, Bendrofluazide (Bendroflumethiazide) 4-thiadiazine-7-sulphonamide 1, Benzthiazide 1-dioxide, whether hydrogenated or Benzylhydrochlorothiazide not; their salts Buthiazide Cyclopenthiazide Cyclothiazide Flumethiazide Hydrochlorothiazide Hydroflumethiazide Methyclothiazide Polythiazide Teclothiazide Trichlormethiazide 54. and other derivatives Clopenthixol of 9-methylenethiaxanthen; their salts Thiothixene Zuclopenthixol 55. Chlorthalidone and other derivatives of Azosemide ortho-chlorobenzenesulphonamide Chloraminophenamide Chlorphenamide Clopamide Dichlorphenamide Indapamide Tripamide Xipamide 56. Citalopram; its salts Escitalopram 57. ; its salts; its derivatives; Clocapramine their salts Lofepramine Mosapramine 58. Colaspase L-Asparaginase 59. Colistin Colistimethate sodium 60. Idarubicin 61. Diazpeam and other compounds Alprazolam containing the chemical structure of Bromazepam dihydro-1, 4-benzodiazepine Camazepam substituted to any degree; their salts Clonazepam Clorazepate Cloxazolam Clozapine Delorazepam Estazolam Ethyl loflazepate Fludiazepam Flunitrazepam Flurazepam Flutoprazepam Halazepam Haloxazolam Ketazolam Loprazolam Lorazepam Lormetazepam Medazepam Metaclazepam Midazolam Nimetazepam Nitrazepam Nordazepam Oxazepam Oxazolam Pinazepam Prazepam Quazepam Temazepam Tetrazepam Triazolam 62. Diethyl para-nitrophenyl phosphate Paraoxon 63. Digitalis, glycosides of; other active Acetyldigitoxin principles of digitalis Acetyldigoxin Deslanoside Digitalin Digitoxin Digoxin Gitoxin Lanatosides 64. Dihydrocodeinone Codoxime O-carboxymethyloxime; its salts; its esters, their salts 65. Dihydrocodeinone enol acetate; its Acetyldihydrocodeinone salts Thebacon 66. Dihydromorphine; its salts; its esters Diacetyldihydromorphine and ethers; their salts 67. 3-(3,4-Dihydroxyphenyl)alanine; its Levodopa salts 68. Dithienylallylamines; Diethylthiambutene dithienylalkyallylamines; their salts Dimethylthiambutene Ethylmethylthiambutene 69. Erythromycin Azithromycin Clarithromycin Dirithromycin Roxithromycin Telithromycin 70. Flufenamic acid; its salts; its esters; Etofenamate their salts 71. ; its derivatives Carmofur Doxifluridine Floxuridine Tegafur 72. Folinic acid; its salts Leucovorin 73. Fusidic acid Fusidates 74. Gallamine; its salts; its quaternary Gallamine triethiodide compounds 75. Gentamicin Isepamicin Netilmicin Sisomicin Tobramycin 76. and other 4-substituted Benperidol derivatives of Bromperidol N-(3-para-fluorobenzoyl- Melperone propyl)piperidine Moperone Pipamperone Spiperone Timiperone Trifluperidol 77. Hexamethylmelamine Altretamine 78. , the following and their Benmoxine alpha-methyl derivatives – Benzyl Isocarboxazid ; Phenethyl hydrazine; Phenelzine Phenoxyethyl hydrazine; their salts; Pheniprazine their acyl derivatives; their salts Phenoxypropazine 79. Hydrocyanic acid, cyanides, other than Cyacetacide ferrocyanides and ferricyanides Potassium cyanide Sodium cyanide 80. Hydroxycinchoninic acids; derivatives Cinchocaine of; their salts; their esters Oxycinchophen 81. Hydroxy-N, N-dimethyltryptamines; Bufotenine their esters and ethers; any salt of any Psilocin substance falling within this item Psilocybin 82. 3-Hydroxy-N-methylmorphinan; its Levorphanol salts; its optical isomers; their salts Dextrorphan 83. 3-Hydroxymorphinan; its salts; its Norlevorphanol optical isomers; their salts, their esters and ethers; their salts 84. 3-Hydroxy-N-phenacylmorphinan; its Levophenacylmorphan salts; its optical isomers; their salts; their esters and ethers; their salts 85. Inosine Pranobex Methisopurinol 86. Isoniazid; its salts; its derivatives; their Glyconiazide salts; any compound with any Iproniazid substance falling within this item Methaniazide Pasiniazide Salinazid Sulfoniazide 87. Kanamycin Amikacin Arbekacin Bekanamycin Dibekacin 88. Lincomycin Clindamycin 89. Melagatran; its salts; its derivatives; Ximelagatran their salts 90. ; its salts; its Azathioprine derivatives; their salts Thiamiprine Thioguanine 91. Mercury, nitrates of; organic Hydrargaphen compounds of; oxides of; mercuric Merbromin (Mercurochrome) ammonium chloride; mercuric chloride; mercuric iodide; mercuric oxycyanide; mercuric thiocyanate; potassiomercuric iodides 92. Methorphan; its salts; its optical Dextromethorphan isomers; their salts 93. Methylaminoheptane; its salts Octodrine 94. 2-Methyl-3-morpholino-1, Moramide intermediate 1-diphenylpropanecarboxylic acid; its salts; its esters; their salts 95. Methylpentynol; its derivatives Meparfynol 96. Alpha-Methylphenethylamine; Amfepramone (Diethylpropion) beta-methylphenethylamine; Benfluorex alpha-ethylphenethylamine; Benzphetamine beta-ethylphenethylamine; their optical Cafedrine isomers; any synthetic compound Ethylamphetamine structurally derived from any of those Fenethylline substances by substitution in the Fenproporex aliphatic part or by ring closure therein Gepefrine (or by both such substitution and such Mebeverine closure) or by substitution in the Mephentermine aromatic ring (with or without Methamphetamine substitution at the nitrogen atom), Pentorex except hydroxyamphetamine, Phendimetrazine methoxyphenamine, pholedrine and Phenmetrazine N-substituted derivatives of ephedrine; Phentermine any salt of any substance falling within Phenylpropanolamine this item Pipradrol Prenylamine Selegiline (Deprenyl) Tamsulosin 97. 1-Methyl-4-phenylpiperidine-4-carbox Pethidine ylic acid; its salts; its esters; their salts Properidine 98. Milbemycins Moxidectin Selamectin 99. Mustine and other N-substituted Bendamustine derivative of di-(2-chloroethyl)amine; Canfosfamide their salts Chlorambucil Chlornaphazine Cyclophosphamide Defosfamide Estramustine Melphalan Perfosfamide Prednimustine Trichlormethine Trofosfamide Uramustine 100. Mycophenolic acid; its salts; its esters Mycophenolate mofetil 101. Noramidopyrine methanesulphonate; Dipyrone its salts 102. ; its salts; its esters Levofloxacin 103. Oleandomycin Troleandomycin 104. Oxytocins Carbetocin Cargutocin Demoxytocin 105. Penicillin Amoxicillin Ampicillin Aztreonam Bacampicillin Benzathine Benzylpenicillin Benzylpenicillin (Penicillin G) Carbenicillin Carfecillin Carindacillin Cloxacillin Dicloxacillin Epicillin Ertapenem Flucloxacillin Imipenem Mecillinam Metampicillin Methicillin sodium Mezlocillin Oxacillin Phenoxymethylpenicillin (Penicillin V) Piperacillin Pivampicillin Pivmecillinam Procaine Penicillin Sulbenicillin Sultamicillin Ticarcillin 106. Pentaerythritol tetranitrate Nitropentaerythritol 107. Perindoprilat; its salts; its esters; their Perindopril salts 108. ; its salts; its derivatives Acepromazine (except dimethoxanate); their salts Acetophenazine (except salts of dimethoxanate); any Butaperazine compound with any substance falling Carphenazine within this item Chlorpromazine Combelen (Propionylpromazine) Cyamemazine Dixyrazine Fluphenazine Homofenazine Mequitazine Mesoridazine Methotrimeprazine Perazine Pericyazine Perimethazine Perphenazine Piperacetazine Pipothiazine Prochlorperazine Promazine Propiomazine Sulforidazine Thiazinamium methylsulfate Thiopropazate Thioproperazine Thioridazine Trifluomeprazine Trifluoperazine Triflupromazine 109. Phenylbutazone; its salts Pyrazinobutazone Thiazolinobutazone 110. 2-Phenylcinchoninic acid; Cinchophen 2-salicylcinchoninic acid; their salts; their esters 111. 5-Phenylhydantoin; its alkyl and aryl Ethotoin derivatives; their salts Mephenytoin Methetoin 3-Methyl-5-phenylhydantoin Phenytoin 112. , the active principles Follicle-stimulating hormone (FSH, of, other than corticotrophins, Follitropin) oxytocins and vasopressin Follitropin alfa Follitropin beta Luteinizing hormone (LH) Lutropin alfa Menotropin Prolactin Somatotropin Somatrem Somatropin (Human growth hormone) Thyroid-stimulating hormone (TSH, Thyrotropin) Urofollitropin 113. Pleuromutilin Tiamulin Valnemulin 114. Polymethylenebistrimethylammonium Decamethonium bromide salts Hexamethonium Pentamethonium bromide 115. Pristinamycin Dalfopristin Quinupristin 116. Propoxyphene; its salts; its optical Dextropropoxyphene isomers; their salts 117. Propranolol; its salts; its derivatives; Levobunolol their salts Nadoxolol Naftopidil 118. Prostaglandins, the following and their Carboprost derivatives – Alprostadil; Bimatoprost; Cloprostenol Dinoprost; Dinoprostone; Latanoprost; Enprostil Misoprostol; Travoprost; Unoprostone; Fenprostalene their salts; their esters Gemeprost Limaprost Ornoprostil Rioprostil Sulprostone Trimoprostil 119. ; its salts; its derivatives; Amitriptylinoxide their salts Butriptyline 120. Recombinant Human Erythropoietin Epoetin alfa 121. Rifabutin Rifampicin Rifapentine Rifaximin 122. Spiramycin Tilmicosin Tylosin 123. Streptomycin Dihydrostreptomycin 124. Strophanthus, glycosides of Cymarin Ouabain Strophanthin 125. Sulphonal; alkyl sulphonals Sulfonethylmethane 126. Suprarenal gland, the active principles Acetoxypregnenolone of; their salts; their derivatives; their Adrenaline (Epinephrine) salts Alclometasone Aldosterone Algestone Amcinonide Arbutamine Beclomethasone Betamethasone Budesonide Chloroprednisone Ciclesonide Clobetasol Clobetasone Clocortolone Cloprednol Cortisone Cortivazol Deflazacort Deoxycorticosterone Desonide Desoxymethasone Dexamethasone Dichlorisone Diflorasone Diflucortolone Difluprednate Dimetofrine Dipivefrin Etiprednol dicloacetate Flucinolone Flucinonide Flucloronide Fludrocortisone Flumethasone Flunisolide Fluocortolone Fluorometholone Fluprednisolone Flurandrenolide Fluticasone Fluzacort Formocortal Halcinonide Halobetasol Halometasone Halopredone acetate Hexoprenaline Hydrocortamate Hydrocortisone Isoflupredone Isoproterenol Loteprednol etabonate Mazipredone Medrysone Meprednisone Methyladrenaline Methylprednisolone Mometasone Noradrenaline Nordefrin Paramethasone Prednicarbate Prednisolamate Prednisolone Prednisone Prednival Prednylidene Pregnenolone Rimexolone Tixocortol Triamcinolone 127. Tetracycline Demeclocycline Doxycycline Lymecycline Meclocycline Methacycline Minocycline Rolitetracycline Tigecycline 128. Theophylline; its salts Choline theophyllinate 129. Thyroid gland, the active principles of; Calcitonin their salts Elcatonin Liothyronine (T3, Triiodothyronine) Salcatonin Thyroxine (T4) 130. 2, 2, 2-Trichloroethyl , esters Trichlorourethan of; their salts Triclofos 131. ; its salts; its derivatives; Alatrofloxacin their salts 132. Tyrothricin Gramicidin Tyrocidine 133. Valproic acid; its salts; its esters Divalproex sodium Valproate 134. Vancomycin Teicoplanin 135. Vasopressins Desmopressin Felypressin Lypressin Ornipressin Terlipressin 136. Virginiamycin Mikamycin

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