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(12) Patent Application Publication (10) Pub. No.: US 2015/0196613 A1 Ahmad Et Al

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(12) Patent Application Publication (10) Pub. No.: US 2015/0196613 A1 Ahmad Et Al US 2015O196613A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2015/0196613 A1 Ahmad et al. (43) Pub. Date: Jul. 16, 2015 (54) SAFFRONTREATMENT METHOD FOR A6M II/02 (2006.01) MAMMALLAN MALADES A6M I5/00 (2006.01) A619/00 (2006.01) (71) Applicants: Aftab Ahmad, Chicago, IL (US); A6M II/00 (2006.01) Christine A. Frysz, Orchard Park, NY (52) U.S. Cl. (US) CPC ............... A61K 36/88 (2013.01); A61 K9/0073 (2013.01); A61M II/005 (2013.01); A61M (72) Inventors: Aftab Ahmad, Chicago, IL (US); II/02 (2013.01); A61M 15/0021 (2014.02); Christine A. Frysz, Orchard Park, NY A6M I5/009 (2013.01); A24F 47/08 (US) (2013.01) (21) Appl. No.: 14/595,095 (22) Filed: Jan. 12, 2015 (57) ABSTRACT Related U.S. Application Data (60) Provisional application No. 61/926,241, filed on Jan. A variety of medicinal compounds comprising crocus sativus 10, 2014 s1 us for the treatment of a plurality of medical ailments are s described. A method of creating a crocus sativus extract is Publication Classification also described. In addition, a variety of embodiments and methods of utilizing inhalation therapeutic delivery mecha (51) Int. Cl. nisms including nebulizers and vaporizers for the vaporiza A6 IK36/88 (2006.01) tion of Crocus sativus comprising medicinal compounds and A24F 47/00 (2006.01) extracts are disclosed. Patent Application Publication Jul. 16, 2015 Sheet 1 of 6 US 201S/O196613 A1 Step a Sowet Step 2 Add Constitudents Step 3 Steep to desired extract COfCetatio Step 4 Reftove COfstituents ses coe Step 6 race extract in inhalation weSSe: FG. Patent Application Publication Jul. 16, 2015 Sheet 2 of 6 US 201S/O196613 A1 s------------------------------------------- a ''. &~~~~~~~~~2,~~~~2,~2,~~~~,~~~\~~~~ Yxx^we S. 38 ----------- 3. {rrrrrrrrrrrrrrr, 32 F. Patent Application Publication Jul. 16, 2015 Sheet 3 of 6 US 201S/O196613 A1 Patiefit Ai intake interface Compressed GaS SO rea FG. A. Patent Application Publication Jul. 16, 2015 Sheet 4 of 6 US 201S/O196613 A1 Air take F. 38 Patent Application Publication Jul. 16, 2015 Sheet 5 of 6 US 201S/O196613 A1 socces 92 era 94. O J Patent Application Publication Jul. 16, 2015 Sheet 6 of 6 US 201S/O196613 A1 S US 2015/O 196613 A1 Jul. 16, 2015 SAFFRONTREATMENT METHOD FOR improvement of digestion and appetite and has been found to MAMMALLAN MALADES be extremely beneficial for providing relief from gas and acidity related problems. Saffron is also used for treating CROSS-REFERENCE TO RELATED cough and is a known therapeutic for insomnia. APPLICATION 0008 Saffron is also regularly used to treat many skin 0001. The present application claims priority based on problems, for example, dry skin, and is used to lighten skin tone. Crocus sativus is used for the treatment of kidney, U.S. provisional application Ser. No. 61/926,241, filed Jan. bladder and liver disorders. It is also believed that saffron 10, 2014. helps to improve circulation of the organs of digestion. Saf fron is considered by many to be a blood purifier and has been BACKGROUND OF THE INVENTION shown to have anti-inflammatory properties as well as help 0002 1. Field of the Invention increase the oxygen content of blood, thus aiding in the over 0003. The present invention relates to herbal mixtures all health and well-being of a person. In addition, crocus used in the treatment of medical maladies. More specifically, sativus has been used to treat asthma and atherosclerosis. the present invention relates to herbal mixtures and extrac 0009. In addition, saffron has been used to help relieve tions comprising crocus sativus used to treat medical mala inflammation associated with arthritis and also with provid dies. ing relief from joint pain. It also has been shown to provide 0004 2. Prior Art relief from lowerback pain. Massaging the gums with saffron 0005. A variety of herbal and plant extracts and prepara may help reduce Soreness and inflammation of the mouth and tions are available today for treating a variety of medical the tongue. maladies affecting the mammalian body. Some preparations 0010 Saffron has also been found to be effective in reliev have been known for literally thousands of years while others ing symptoms of pre-menstrual symptoms (PMS). Saffron is are just being scientifically discovered to have curative even recommended for use during pregnancy as the herb is effects. Effective plant extracts are highly desired as a “natu used to elevate body temperature. In addition, saffron is railway to treat medical maladies. It is believed that “natural thought to be an antioxidant and have anti-cancerous and preparations will minimize potential adverse effects as com anti-tumor properties. It also may have a protective effect on pared to synthetic preparations. For example, U.S. Pat. No. the heart. 4,986,895 to Grossman et al., is directed to the use of water 0011 Prior art examples that demonstrate some of the soluble plant extracts for the treatment of virus skin infec medicinal uses of saffron can be found in U.S. Pat. No. tions. U.S. Pat. No. 5,178,865 to Ho et al., is directed to the 6,607,756 to Rosenstiel which discloses the use of pure pow use of Chinese herbal extracts for the treatment of HIV related dered saffronto increase blood flow, to relieve pain and mini disease. Ho discloses a total of 56 herbal extracts that were mize skin dryness. U.S. Pat. App. Pub. No. 2003/008.6981 to screened for anti-HIV activity using various in vitro tech Seiki et al., discloses an ingestible saffron pill composed of a niques. glycerin fatty acid ester that is used in the treatment of pre 0006. In particular, the medicinal properties of saffron menstrual symptoms (PMS). U.S. Pat. App. Pub. No. 2005/ (crocus sativus) have been generally known as the herb has 0158411 to Vail et al., now U.S. Pat. No. 7,344,740 discloses been used for many years in traditional medicine. Today, inhalation of a combination of peppermint oil complemented crocus sativus is being Scientifically investigated for its many by saffron and other herbs that may be used to treat nausea medicinal benefits. The pistill of the crocus flower is com induced by cancer chemotherapy treatment. U.S. Pat. No. posed of a stigma, a style, and an ovary. The Stigma has a 8,569.247 to Eidenberger, discloses embodiments of compo bright red color and contains many useful components sitions derived from Saffron and gardenia for medicinal treat including medicinal constituents, flavoring compounds and mentS. pigments. These useful components have been convention 0012 However, the prior art does not disclose saffroncon ally harvested from the pistils of open crocus flowers. Both taining medicinal therapeutic mixtures that are designed to be the stigma and the petals of the crocus flowers are believed to vaporized or nebulized and, thus, provide treatment of these possess medicinal properties. For example, both the saffron various medical ailments, such as pre-menstrual symptoms Stigma and petals are said to be helpful for depression. (PMS), through inhalation of a saffron comprising therapeu 0007 Saffron (crocus sativus) has been the subject of tic aerosol. There exists, therefore, a need for a medicinal numerous clinical investigations, examples of which are dis extract or therapeutic mixture comprising crocus sativus to closed in articles by M. Agha-Hosseini et al., BJOG2008, relieve medical ailments that is designed to be delivered 115, p. 515-519: Su Hee Jang et al., Complimentary and through various inhalation methods. In addition, there exists Alternative Medicine 2014, 14:11, p. 1-13: Vijaya Bhargava a need for a medicinal extract or therapeutic mixture thereof K, International Journal of Pharmacy and Pharaceutical comprising crocus sativus that is designed to be vaporized or Sciences 2011, Vol. 3, suppl. 3, p. 22-26: F. I. Abdullaev et al., nebulized using various apparatus and inhalation methods. Cancer Detection and Prevention 2004, vol. 28, p. 426-432; 0013 Vaporization offers a means to extract and concen and R. Srivastava et al., Pharmacogn Rev. 2010, Jul.-Dec. trate therapeutic agents, such as those separated from a natu 4(8), p. 200-208, all of which are incorporated by reference rally occurring plant, through a pure aerosol vapor mist. In an herein. These investigations and others have identified the embodiment of the present invention, vaporization of plants, herb to comprise medicinal benefits for numerous medical herbs, their extracts, and combinations thereof, is provided. In ailments. Among these scientific studies, crocus sativus has one such embodiment, the vaporization of Crocus sativus is been identified as a sedative, a stimulant, in particular, a provided. In the embodiment, the vaporization method uti central nervous system stimulant, an antispasmodic, and a lizes different solvents and temperatures to modify and/or diaphoretic. Saffron, crocins and crocetin have been shown to concentrate the therapeutic Substance, for example, but not inhibit breast cancer cell proliferation. It is used for the limited to, the saffron stigma, the saffron petals, dried saffron US 2015/O 196613 A1 Jul. 16, 2015 threads and powders. "Saffron threads' are generally known the release valve is actuated, pressure from within the con to be dried stigmas of the saffron plant. tainer causes the therapeutic medium to exit the container at 0014. An alternate delivery method is to inhale smoke a high velocity. A propellant may also be contained there resulting from the burning of a plant, herb or combination within to aid in the expulsion of the therapeutic medium from thereof. However, the burning process may create potentially the container. The propellant mixes with the therapeutic toxic materials or compounds such as tars, which are gener medium inside the container Such that when the contents ally not desirable.
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