Catalog # Aliquot Size A828-40N-30 30 µg A828-40N-200 200 µg

A828-40N-1000 1 mg Recombinant Human AITRL (TNFSF18) Recombinant human expressed in E. coli cells

Catalog # A828-40N Lot # G3211-3

Product Description Specific Activity

Recombinant Human AITRL (TNFSF18) was expressed in E. coli cells. The protein accession number is Q9UNG2

Gene Aliases

Activation-inducible TNF-related ligand, AITRL, Glucocorticoid- induced TNF-related ligand, GITRL, hGITRL, ligand superfamily member 18, TNFSF18, TL-6, Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18)

Endotoxin Level

<1.0 EU/µg of recombinant protein as determined by the LAL method.

Formulation

Lyophilized from a 0.2 micron filtered solution in Tris and salt Purity

Reconstitution Protocol Recombinant Human AITRL Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human (TNFSF18) resolved on a 17% SDS- or bovine serum albumin. PAGE gel under reducing conditions and stained with Storage and Stability Coomassie Brilliant Blue G-250

The lyophilized protein is stable for at least one year from date of Approx. MW 14.2 kDa receipt at -70°C. Upon reconstitution, this can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. Recombinant Human AITRL Scientific Background (TNFSF18) Recombinant human protein expressed in E. coli cells TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting Catalog Number A828-40N cells, CD4- CD8- double negative thymic precursors, and in the Specific Lot Number G3211-3 eye. TNFSF18 works to mediate the interactions between T cells Purity 95% and endothelial cells, and growth. It has been shown that Stability 6 mos. at –20oC from date of shipment TNFSF18's expression is transiently up-regulated by Storage & Shipping The lyophilized protein is stable for at proinflammatory stimulation. least one year from date of receipt at - 70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

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FOR IN VITRO RESEARCH PURPOSES ONLY. NOT INTENDED FOR USE IN HUMAN OR ANIMALS.