FANCE Antibody Cat. No.: 27-008
FANCE Antibody
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human FANCE.
TESTED APPLICATIONS: ELISA, WB
FANCE antibody can be used for detection of FANCE by ELISA at 1:312500. FANCE APPLICATIONS: antibody can be used for detection of FANCE by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
POSITIVE CONTROL: 1) Cat. No. 1211 - HepG2 Cell Lysate
PREDICTED MOLECULAR 59 kDa WEIGHT:
Properties
PURIFICATION: Antibody is purified by peptide affinity chromatography method.
CLONALITY: Polyclonal
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
September 27, 2021 1 https://www.prosci-inc.com/fance-antibody-27-008.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.
CONCENTRATION: batch dependent
For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: FANCE antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Additional Info
OFFICIAL SYMBOL: FANCE
ALTERNATE NAMES: FANCE, FACE, FAE
ACCESSION NO.: NP_068741
PROTEIN GI NO.: 11345454
GENE ID: 2178
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex.The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, BACKGROUND: FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
REFERENCES: 1) Wang, X., (2007) Mol. Cell. Biol. 27 (8), 3098-3108.
ANTIBODIES FOR RESEARCH USE ONLY.
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