Datasheet Version: 2.0.0 Revision date: 16 Nov 2020

Importin Alpha 4 (KPNA4) Antibody Catalogue No.:abx031156

WB analysis of (1) HeLa cell lysates, (2) mouse brain tissue lysates, and (3) HepG2 cell line lysates.

The nuclear import of karyophilic is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or , are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The encoded by this shares the sequence similarity with Xenopus -alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Target: Importin Alpha 4 (KPNA4)

Clonality: Polyclonal

Reactivity: Human, Mouse

Tested Applications: ELISA, WB

Host: Rabbit

Recommended dilutions: WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.

Conjugation: Unconjugated

Immunogen: KLH-conjugated synthetic peptide between 1-30 amino acids from the C-terminal region of human Importin alpha-4 (KPNA4). Isotype: ForIgG Reference Only

Purification: Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

UniProt Primary AC: O00629 (UniProt, ExPASy)

KEGG: hsa:3840

v1.0.0 Abbexa Ltd, Cambridge, UK · Phone: +44 1223 755950 · Fax: +44 1223 755951 1 Abbexa LLC, Houston, TX, USA · Phone: +1 832 327 7413 www.abbexa.com · Email: [email protected] Datasheet Version: 2.0.0 Revision date: 16 Nov 2020

String: 9606.ENSP00000334373

Buffer: PBS containing 0.09% sodium azide.

Note: This product is for research use only.

For Reference Only

v1.0.0 Abbexa Ltd, Cambridge, UK · Phone: +44 1223 755950 · Fax: +44 1223 755951 2 Abbexa LLC, Houston, TX, USA · Phone: +1 832 327 7413 www.abbexa.com · Email: [email protected]