Centre for Health Evaluation & Outcome Sciences

Health Research in the Heart of Vancouver

Annual Report 2011–2012 Centre for Health Evaluation and Outcome Sciences St. Paul’s Hospital 588 – 1081 Burrard Street Vancouver, BC V6Z 1Y6

Telephone: 604-806-9958 Fax: 604-806-8005 www.cheos.ubc.ca [email protected]

Twitter: @CHEOSNews Facebook: www.facebook.com/CHEOSNews Table of Contents

Contents Appendices

Director’s Message 4 Appendix I: Peer Reviewed Journal Publications 28 About CHÉOS 5 Appendix II: New Scientist Appointments 6 Invited Presentations 42

CHÉOS Scientists 8 Appendix III: Abstracts 53 Awards and Accomplishments 9

Research Highlights 12

Pharmacoeconomics 12 Urban Health 13 Heart Health 17 CORE 17

Conferences & Educational Sessions 18

Work in Progress Seminars 19

CHÉOS and Social Media 23

Hires and Departures 24

Research Support Services 25

Key Contacts 26 `Centre for Health Evaluation and Outcome Sciences 4 Annual Report 2011–12

Director’s Message

I am pleased to introduce the Centre for Health Evaluation and Outcome Sciences’ (CHÉOS) Annual Report for 2011/12. The Centre has seen much success this past year, and we are delighted that in January of 2012, CHÉOS received approval and became a University of British Columbia (UBC) Faculty of Medicine Research Centre. As part of this significant achievement, we look forward to working with a newly established External Advisory Committee for the Centre consisting of academic, industry and government partners. With our scientists representing six departments within UBC, including the School of Population and Public Health and numerous divisions within the Faculty of Medicine, in addition to the Faculty of Pharmaceutical Sciences and the School of Nursing in the Faculty of Applied Sciences, we anticipate even greater collaboration and coordination with one of Canada’s leading universities.

Four new scientists joined CHÉOS in 2011/12: Dr. Nick Bansback from UBC’s School of Population and Public Health, Dr. Richard Sawatzky from the School of Nursing at Trinity Western University, and Drs. Martha Mackay and Peggy Simpson, both clinical nurse specialists with Providence Health Care and faculty members in UBC’s School of Nursing. We also added over thirty trainees and twenty research staff members, demonstrating the Centre’s continued commitment to providing a rich training environment for new talent.

Several of our major research initiatives received renewal funding from the Canadian Institutes of Health Research (CIHR) in 2011/12. These include the Health and Housing in Transition study led by Dr. Anita Palepu in Vancouver and the Cedar Project led by Drs. Patricia Spittal and Martin Schechter. We were also happy to see a CIHR New Emerging Team Grant for Rare Diseases awarded to Dr. Larry Lynd and his colleagues.

This Annual Report highlights the accomplishments of CHÉOS scientists, staff and students, and recognizes their efforts to undertake, support and achieve personal and professional excellence. Our scientists were appointed to new leadership positions, given opportunities to lead new impactful initiatives and our research endeavors garnered local and international attention in the media. The Centre also hosted numerous well-attended workshops and seminars promoting collaboration, best practices in research as well as knowledge sharing across health disciplines.

I would like to take this opportunity to thank the Providence Health Care Research Institute for their support of our Centre, as well as all of my CHÉOS colleagues for their outstanding efforts contributing to not only our Centre’s success, but to advancing health outcomes research. We look forward to continuing our efforts to support and conduct collaborative research that informs improved patient care, and I hope you enjoy reviewing our achievements contained in this report.

Aslam Anis, PhD, FCAHS Director, Centre for Health Evaluation and Outcome Sciences

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About CHÉOS CHÉOS is an interdisciplinary research collective founded to marginalized groups including Canada’s First Nations and pursue excellence in research through the rigorous ethnic minorities. Our research also includes the study of evaluation, interpretation and dissemination of health people who are critically or chronically ill and the elderly. outcomes information. As clinicians and epidemiologists, All of these populations require complex care that CHÉOS researchers are embedded in the health care system challenges the fabric of our health care system, and to ensure our research is relevant and driven by clinical improved care for these populations is urgently needed. need. In addition to conducting our own research, the centre’s other primary function is to offer methodological As a testament to the quality of research performed by expertise to researchers, including assistance with study CHÉOS scientists, two are Canada Research Chairs (Drs. design, statistics, health economics, data management and Carlo Marra and Martin Schechter) and nine have been grant facilitation for both health outcomes research and named Foundation for Health Research clinical trials. (MSFHR) Scholars (former member Dr. Adrian Levy, and currently Drs. Karin Humphries, Anita Palepu, John Gill, CHÉOS was established in 1997, and is based at St. Paul’s Carlo Marra, Larry Lynd, Chris Richardson, Nadia Khan Hospital in Vancouver, British Columbia. CHÉOS is a centre and Eugenia Oviedo-Joekes). Since 2005, CHÉOS scientists of the Providence Health Care Research Institute (PHCRI), have also collectively published over 1,400 peer-reviewed and in 2012, was also officially established as a University manuscripts. of British Columbia (UBC) Faculty of Medicine Research Centre. Our unique position as a health outcomes unit CHÉOS is structured to encompass both existing and new situated in a teaching and research hospital is ideal for areas of research interest. Related objectives are threefold: to supporting clinical epidemiology. Additionally, we are generate more interest and excitement in multi-disciplinary committed to creating an inclusive, dynamic and research; to respond to emerging issues in the population cooperative work environment in which younger researchers health arena; and to provide a mechanism that can facili- are mentored, established researchers are supported, and all tate cross-discipline dialogue and multi-disciplinary grant participants are encouraged to pursue personal and opportunities. CHÉOS and the health partners we work with professional challenges. believe that our research is needed to form a continuous loop of improvement where clinical practice informs research, CHÉOS investigators are known for ground breaking and research informs clinical practice. Ultimately, we seek research to improve care for our most vulnerable and to influence change and improve health and health systems marginalized urban populations. Our research includes the by empowering decision makers to make positive change study of urban populations with mental health issues, based on evidence. addictions and infectious diseases. It involves the health of

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New Scientist Appointments

Dr. Nick Bansback, PhD Dr. Richard Sawatzky, PhD, RN

• Assistant Professor, School of • Associate Professor, School of Population and Public Health, UBC Nursing, Trinity Western University • Visiting Associate Professor, UBC Dr. Nick Bansback joined CHÉOS as a Research Scientist in January of this year. He is an Assistant Professor at the Dr. Sawatzky joined CHÉOS as a scientist in December School of Population and Public Health at the University of 2011, bringing methodological expertise, and a programme British Columbia. His research broadly seeks to use of research that is an excellent fit with our mandate. His decision science to improve policies and practices in health. research focuses on methods of patient-reported outcomes Interests include decision-analysis techniques such as cost- and quality of life measurement, and the intersections of effectiveness modeling and value of information analysis, spirituality, religiosity, culture, and other sources of diversity preference elicitation such as discrete choice experiments in various health care contexts, including those for people and the analytic hierarchy process, and network meta- with life limiting conditions, and their family caregivers, analysis. Applications of Dr. Bansback’s research involves who are in need of a palliative approach. the development of innovative decision tools for integration into clinical decision making. He has a particular interest in examining the implications of population heterogeneity with respect to individuals’ self- Dr. Bansback has a BSc in Mathematics majoring in reports about their health status and quality of life. His Operations Research, an MSc in Health Services Research, current research includes studies on a palliative approach and in 2010 he completed his PhD in Health Economics in nursing, the use of computerized assessment systems, and Decision Sciences at the University of Sheffield, UK. methods for the measurement of quality of life in longitudinal studies, spiritual and religious diversity in healthcare, edu- cational approaches for patients with colorectal cancer, and patients’ experiences with knee surgery. His clinical background is in palliative care and medical nursing care, and he has been part of the School of Nursing faculty at TWU since 2002. He also teaches courses in the Master of Science Nursing programme on knowledge synthesis and quantitative research methods.

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New Scientist Appointments

Dr. Martha Mackay, PhD, RN, CCN(C) Dr. Peggy Simpson, PhD, RN

• Clinical Nurse Specialist, Cardiology Heart Centre, • Clinical Nurse Specialist, Consultation Liaison Psychiatry, St. Paul’s Hospital Providence Health Care • Clinical Assistant Professor, School of Nursing, UBC • Adjunct Professor, School of Nursing, UBC • Cardiovascular Outcomes Research Fellow, Cardiac Services BC We are happy to announce that Dr. Peggy Simpson has also joined CHÉOS as a scientist this past year. She is currently a We are pleased to announce that Dr. Martha Mackay also clinical nurse specialist in the Mental Health Program and joined CHÉOS this past year. She is a clinician-scientist the Department of Psychiatry at St. Paul’s Hospital and dividing her time between the roles of Clinical Nurse adjunct professor at UBC’s School of Nursing. Her role, as Specialist (CNS) in Cardiology at the St. Paul’s Hospital Heart such, is focused primarily on clinical research evidence- Centre, and Clinical Assistant Professor at the UBC School of based practice and knowledge translation. Formerly she held Nursing. She has been practicing for more than 30 years in an academic appointment at The University of Hong Kong critical care and cardiac nursing, and has also spent many Faculty of Medicine in the Department of Nursing Studies years as a critical care nursing educator, with 15 years as a (assistant professor). CNS. She completed her initial nursing education at George Brown College in Toronto, and has since earned her BSN, Dr. Simpson received her undergraduate (BN) and MSN and PhD degrees at UBC. graduate education (MN) from the University of Calgary and her doctoral degree from the University of Hong Kong. She Dr. Mackay has been the recipient of a CIHR Clinical Re- has received grants from the Government of Alberta and the search Fellowship, the Cardiac Services BC Fellowship in Research Grants Council of Hong Kong. Dr. Simpson is also Cardiovascular Outcomes, and more recently, a Heart and a consultant to the Ministry of Health, Provincial Mental Stroke Foundation of Canada Research Scholarship. Her Health and Substance Use Sector Survey Group. research focuses on sex, gender and ethnic differences in symptoms; treatment-seeking behaviour and outcomes Dr. Simpson’s primary research focus is on the prevention, following acute coronary syndrome and cardiac procedures; identification, and management of delirium in an acute care and finally, the evaluation of interventions to improve setting. Dr. Simpson developed the Family Nursing Practice patients’ cardiac risk behaviours. Scale, which has been used worldwide in numerous family nursing research initiatives. She is currently partnering in a CIHR international research collaboration to advance the practice of family nursing in health care services.

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CHÉOS Scientists

Since its inception, CHÉOS has aimed to bring together a multidisciplinary collective of health care researchers and professionals whose primary focus is health outcomes research. This research pool includes renowned, well-funded experts in their fields who draw from a significant base of individual and collaborative research experience on the local, national and international levels.

CHÉOS scientists for 2011–2012:

Aslam Anis, PhD, FCAHS Martha Mackay, PhD, RN CCN(C) Najib Ayas, MD, FRCPC Carlo A. Marra, PharmD, PhD, BSc, FCSHP Nick Bansback, PhD Eugenia Oviedo-Joekes, PhD Monica Beaulieu, MD, FRCPC, MHA Anita Palepu, MD, MPH, FRCPC Carl J. Brown, MD, MSc, FRCSC Adam Peets, MD, MSc Geoffrey Cundiff, MD, FACOG, FACS P. Terry Phang, MD Peter Dodek, MD, MHSc Stephen Pinney, MD Josie Geller, PhD, R. Psych Manoj Raval, MD, MSc, FRCSC Jagbir Gill, BSc, MPH, MD, FRCPC Chris G. Richardson, PhD, MSc, BA John Gill, MD Richard Sawatzky, PhD, RN Sabrina Gill, MD, MPH, FRCPC Martin Schechter, OBC, MD, PhD, FRCPC, FRSC, FCAHS Eric Grafstein, MD Christian G. Schütz, MD, PhD, MPH Devin Harris, MD, CCFP (EM), MHSc, PhD Kamran Shojania, MD, FRCPC Natalie Henrich, PhD, MPH Peggy Simpson, PhD, RN Karin Humphries, MSc, MBA, DSc Joel Singer, PhD Garth Hunte, MD, PhD Patricia Spittal, PhD Nadia Khan, MD Rob Stenstrom, MD, PhD, CCFP-EMT Lorne Korman, PhD, R. Psych Verena Strehlau, MD, PhD, RPN Jean-François Kozak, PhD Iris Torchalla, PhD Michael Krausz, MD, PhD, FRCPC Barbara Trerise, MHSc Adeera Levin, MD, FRCPC Brian Westerberg, MD, MHSc, BA, FRCSC Larry D. Lynd, BSP, PhD Hubert Wong, PhD, BASc

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Awards and Accomplishments Javier Landaeta photo/Faculty of Medicine photo/Faculty Landaeta Javier

Dr. Anis accepts his mentorship award from the Faculty of Medicine.

Dr. Aslam Anis became a Fellow of the Canadian Dr. Geoffrey Cundiff received the 2011 Foundress Mission Academy of Health Sciences. He was also awarded a 2012 Team Award from St. Paul’s Hospital Maternity Services Award for Excellence in Mentoring Early Career Faculty from Program. He was also appointed regional head, Obstetrics the UBC Faculty of Medicine. and Gynecology for Providence Health Care (PHC) and Vancouver Coastal Health (VCH). In January 2012, Dr. Nick Bansback became an assistant professor at UBC’s School of Population and Public Health. Dr. Anne Gadermann was awarded a Michael Smith Foundation for Health Research (MSFHR) 2011 Research Dr. Carl Brown received two awards for his Trainee Award for her work titled, “Investigating the accomplishments in 2011: the Best Resident Teacher Award relationship between residential stability, physical and for UBC’s Department of Surgery, and the award for top mental health, and quality of life in homeless and vulnerably clinical paper at the Canadian Surgical Forum for his pre- housed individuals: A multi-site longitudinal study.” sentation, “Retrospective comparison of early complications rate in open vs. suture closure rectal lesions excised using Dr. John Gill was elected president of the Canadian Society Transanal Endoscopic Microsurgery.” He also received a of Nephrology. He was also granted tenure at UBC’s Faculty research grant from the Canadian Society of Colorectal of Medicine as an associate professor. Surgeons entitled, “A multi-centre randomized controlled trial of sutured vs. unsutured management of surgical defects in patients undergoing Transanal Endoscopic Microsurgery.”

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Awards and Accomplishments continued

Dr. Eric Grafstein was appointed to a combined role as regional head of the Department of Emergency Medicine and regional medical director of Emergency Medicine for PHC and VCH. He also received the 2011 Providence Health Care Research Institute (PHCRI) Research and Mission Award.

PhD Student Stephanie Harvard has been granted a CIHR Doctoral Award for Patient-Oriented Research—Health Economics. She also received a Frederick Banting and Charles Best Award Graduate Scholarship.

Dr. Karin Humphries now holds the UBC Heart and Stroke Foundation Professorship in Women’s Cardiovascular Health.

Dr. Nadia Khan received a MSFHR Career Investigator Award in 2011 for her research on improving chronic cardiovascular disease management in ethnocultural patients. She also became an associate faculty member at UBC’s School of Population and Public Health.

Dr. Eugenia Oviedo-Joekes received a MSFHR 2011 Career Investigator Award for her work on the Study to Assess Long- Term Opioid Medication Effectiveness (SALOME).

Dr. Adeera Levin, executive director of the BC Provincial Renal Agency, received St. Paul’s Hospital’s Howard B. Stein Master Teacher Award for 2011, an award given to a physician deemed by his or her residents to be the most outstanding teacher.

Dr. Larry Lynd was named a scholar for the Peter Wall Institute for Advanced Studies in August 2011. He was also appointed to the Health Canada Scientific Advisory Committee on Nonprescription Drugs.

Dr. Carlo Marra’s Tier II Canada Research Chair in Pharmaceutical Outcomes was renewed in 2011. He

Javier Landaeta photo/Faculty of Medicine photo/Faculty Landaeta Javier became a member of the CIHR Operating Grant Evaluation Committee for Health Services Research and the (L to R) Dr. Martin Schechter and UBC Faculty of Medicine Dean Gavin Stuart. CIHR Drug Safety and Effectiveness Network Committee, as well as a full professor in the Faculty of Pharmaceutical Sciences at UBC.

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Awards and Accomplishments continued

The UBC Faculty of Medicine awarded Dr. Anita Palepu the Distinguished Achievement Award for Service to the University and Community.

PhD Candidate Stephen Pan received a U.S. Fulbright student grant (China).

Health Economist Adam Raymakers was one of six students to receive the Office of the Dean, Research & Graduate Studies Travel Award from the UBC Faculty of Pharmaceutical Sciences.

CIHR awarded Dr. Chris Richardson with a 2011 CIHR New Investigator Award for his BC Adolescent Substance Use understanding will be gained in terms of what types of Survey (BASUS). patients are more likely to consider transplant tourism, whether these patients understand the potential risks The UBC Faculty of Medicine honoured Dr. Martin associated with this practice, whether they understand the Schechter for his distinguished service as the Head of the options for transplantation locally and what has prevented Department of Health Care and Epidemiology from 2000– them from pursuing these options locally. The research will 2008 and the Director of UBC’s School of Population and also aim to better understand strategies that could help Public Health from 2008–2010. increase the ability of patients to get transplanted locally and to deter them from opting for transplant tourism. Dr. Kamran Shojania was promoted to clinical professor status from clinical associate professor in July 2012 in UBC’s Dr. Nick Bansback, along with Drs. Carlo Marra and Larry Division of Rheumatology. Lynd, has received funding from The Arthritis Society for his study that will use iPads to try and improve decision-making Dr. Iris Torchalla and her colleagues Drs. Michael Krausz, in patients needing osteoarthritis medication. Patients who Verena Strehlau and Kathy Li, received the Zeldowicz visit pharmacies will be asked to use an app Dr. Bansback Clinical Science Poster Award for a poster on their study has developed for the iPad to help them become better about mental health and suicidality in homeless women. The informed about treatment for their condition. He will test poster was presented at UBC Department of Psychiatry’s 26th whether the app helps patients make more informed Annual Research Day in Fall 2011. decisions when it comes to their own health care.

The UBC Department of Surgery (Otology & Neurotology) In fall 2011, Dr. Carl Brown received a research grant from promoted Dr. Brian Westerberg to clinical professor in July the Canadian Society of Colorectal Surgeons. Dr. Brown and 2011. Dr. Westerberg received the P.J. Doyle Teaching Award his CHÉOS colleagues Drs. Manoj Raval and Terry Phang from the Division of Otolaryngology in UBC’s were featured in Promise, St. Paul’s Hospital Foundation’s Department of Surgery in June 2011. magazine, for their development of a centre for excellence in colorectal surgery at St. Paul’s Hospital. Dr. Adeera Levin, along with fellow CHÉOS scientists Drs. Patricia Spittal, John Gill, Jagbir Gill, and Chris Richardson, received a two-year operating grant from CIHR for their study of “transplant tourism,” the practice of travelling to another country to purchase an organ for transplantation purposes. Through this research, a better

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Research Highlights

Pharmacoeconomics in the news

In March of 2012, the study entitled, “Cost-effectiveness methadone maintenance therapy. The findings were drawn of diacetylmorphine versus methadone for chronic opioid from the North American Opiate Medication Initiative dependence refractory to treatment,” received widespread (NAOMI), a trial of medically prescribed that took media attention as it found that medically prescribed heroin place in Vancouver and Montreal from 2005 to 2008, as is more cost-effective than methadone for treating long-term well as administrative drug data from British Columbia. street heroin users. Led by Dr. Aslam Anis, Centre director, this study received attention from multiple news Those in the methadone therapy group generated an outlets, including CBC News, The Toronto Star, The Daily average lifetime societal cost of $1.14 million per person, Beast, Time and The Daily Mail. while those in the diacetylmorphine group generated a lesser cost of $1.09 million. The study considered treatment This study was published in the Canadian Medical expenditures, estimated costs for drug therapies and costs Association Journal (CMAJ) and attributed most of the borne by the justice system. economic benefits to the fact that recipients of medically prescribed heroin (diacetylmorphine) stayed in treatment The study is a collaboration between CHÉOS, UBC, longer and spent less time in relapse than those receiving Université de Montréal and the Northern Ontario School of methadone. Both results are associated with reduced Medicine. Co-authors on the publication include Bohdan criminal activity and lower health care costs. Nosyk, Daphne P. Guh, Nicholas J. Bansback, Eugenia Oviedo-Joekes, Suzanne Brissette, David C. Marsh, Evan Additionally, an individual in the diacetylmorphine group Meikleham and Martin T. Schechter (continued over). was more likely to live longer than someone receiving

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Dr. Michael Krausz (far right) received a grant from Bell to develop an online mental health web portal.

Research Highlights continued costs in Canada.” In September 2011, Dr. Anis’ previous research on the subject gained media attention in The NAOMI study was also led by researchers from PHC, The National Post. CHÉOS and UBC, and was a randomized trial aimed at testing whether medically prescribed heroin was more The Pharmacoeconomics Program is a multidisciplinary team effective than methadone therapy for individuals who were consisting of physicians, biostatisticians, economists, not currently benefiting from conventional treatment. pharmacists, and epidemiologists. Centre Director Dr. Aslam Anis heads the program, which undertakes projects in a NAOMI was North America’s first-ever clinical trial of variety of areas of study, including health technology prescribed heroin, and enrolled 251 patients. The results of assessment, economic burden of illness and health services NAOMI, published in the New England Journal of Medicine, research, and pharmaceutical pricing and regulation. showed that patients treated with the prescribed heroin were more likely to stay in treatment or quit heroin altogether and more likely to reduce their use of illegal drugs and other Dr. Krausz appointed lead in youth mental illegal activities than patients treated with oral methadone. health initiative An online implementation tool is available at http://www. cheos.ubc.ca/. This tool allows for the calculation of costs This past year, UBC and Bell announced a $1M gift to and savings for any jurisdiction by inputting relevant establish the Bell Youth Mental Health IMPACT Project demographic data. which will be led by Dr. Michael Krausz. The project will include: research into how BC’s young adults are currently Researchers to explore the impact of using online mental health resources and what is lacking; testing of a web-based psychotherapy program that includes price-caps in the pharmaceutical industry an online self-assessment tool along with self-guided exer- cises and techniques; creation of a similar online program for Dr. Aslam Anis, with scientists Drs. Marra and Lynd, anxiety; and testing the effectiveness of various online received a two-year operating grant in January 2012 from communication channels, not only between experts and CIHR for their research project, “The impact of price-caps on patients but also between experts and primary care providers the generic pharmaceutical industry and provincial drug plan (continued over).

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(L to R) Drs. Eugenia Oviedo-Joekes and Michael Krausz, two of the investigators for SALOME.

Research Highlights continued This report was based on a survey conducted by Dr. Krausz and co-investigator Dr. Christian Schutz. 500 homeless “Despite the high prevalence of anxiety and depression, individuals in three BC cities were surveyed, providing especially among those in late adolescence and early comprehensive data on key health indicators and risk factors adulthood, the proportion of people who actually receive among this diverse group. “Our study shows that the treatment in time is quite low,” Dr. Krausz said in an majority of homeless people experience some kind of interview with UBC. “Too often, their first opportunity to trauma during childhood. Given that, it is really important access care results from an encounter with police or a trip to start discussing earlier interventions to cope with mental to the emergency room. Enabling young adults to get help health challenges,” Dr. Krausz said. early will reduce the chances that their condition will lead to substance abuse or attempts at suicide.” Recognition for SALOME trial researcher At first, the project will focus on underserved communities and involve partnerships with primary care Dr. Eugenia Oviedo-Joekes received a MSFHR 2011 Career physicians, school counselors, police and family organizations Investigator Award for her work on the Study to Assess Long- to facilitate use of the platform by those who need it. Insights Term Opioid Medication Effectiveness (SALOME). from these pilot studies will be used to develop a province- wide mental health web portal. SALOME is a clinical trial that will test whether hydromorphone (Dilaudid®), a licensed medication, is as good as diacetylmorphine, the active ingredient of heroin, CHÉOS researchers on homelessness at benefiting people suffering from chronic opioid addiction who are not benefiting sufficiently from other treatments In May 2012, Dr. Krausz shared findings of the BC Health (continued over). of the Homeless Survey Report with the City of Vancouver.

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Research Highlights continued

This study will also test if those effectively treated with these two injectable medications can be successfully switched and retained to the oral formulations of the medications.

The SALOME study follows up on an unexpected finding of the NAOMI study, which was that injection patients could not accurately discriminate whether they were receiving diacetylmorphine or hydromorphone. Investigators also observed similar results and benefits with both these drugs, although the small number of participants receiving hydromorphone did not permit us to draw any definite and scientifically valid conclusions as to the efficacy of hydromorphone as a treatment option.

Should hydromorphone be proven to be as good as diacetylmorphine, the benefits of this form of injectable treatment may be more feasible and achievable without the emotional and regulatory barriers often presented by heroin At Home/Chez Soi in the media maintenance. Therefore, the NAOMI investigators designed SALOME to test this hypothesis as a next step of the NAOMI Preliminary results of the At Home/Chez Soi study broke study. ground in the national media. The five-year project is exploring the best combination of housing and supports for homeless individuals with mental illness. Being undertaken Dr. Richardson recognized for his research in five Canadian cities, the study has housed over 1,000 on adolescents and substance use participants, with another 980 receiving community support. Investigators, including Drs. Verena Strehlau, Krausz and Dr. Chris Richardson received a 2011 CIHR New Investigator Schutz, are striving to assist policy makers in understanding award for his work on the British Columbia Adolescent what initiatives and supports are needed to solve chronic Substance Use Survey (BASUS). BASUS is a multi-year homelessness in Canada. research study of BC teenagers’ attitudes about, and experiences with, tobacco, alcohol, marijuana, and other The study employs a Housing First approach, which drugs. The survey also asks about a range of other topics, provides individuals with housing and support services that including extracurricular activities, self-esteem, resilience, are customized to meet their needs. The research portion of depression, family life, and physical health and development. the study will end in 2013.

The goal of BASUS is to investigate patterns in the progression of substance use, using an internet-based web survey, in approximately 5,000 adolescents as they progress through the first three years of secondary school. The information gained from this study will improve our understanding of the determinants of individual differences in the development of alcohol, tobacco, and marijuana use. The findings will be shared with health promotion experts and school district supervisors to inform local drug education and health promotion activities.

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Research Highlights continued isabelle linden photo/chÉOS

The Cedar Project receives renewal grant A new lease for the Health and Housing in Transition Study The Cedar Project was awarded two new grants from CIHR: a planning grant and a three-year operating grant. The Health and Housing in Transition Study (HHiT), a longitudinal study looking at the health and housing status Aboriginal investigators and collaborators, forming the of homeless and vulnerably housed single adults in Cedar Project Partnership, have governed the research and Vancouver, Ottawa and Toronto, received renewal funding knowledge translation process from the beginning of the from CIHR this year. Cedar Project. Together with this partnership, Principal Investigators Drs. Patricia Spittal and Martin Schechter aim Dr. Anita Palepu, the lead investigator for the Vancouver site, to introduce a surveillance initiative for sexually transmitted and her fellow researchers are exploring whether changes infections, explore what helps and hinders youth from in housing status are associated with changes in mental and entering into addiction treatment, and examine whether physical health, alcohol and drug use, social supports and using mobile phone technology can help prevent hepatitis C utilization of health care services. Researchers hope to and HIV and improve health outcomes. identify risk factors, and community, interpersonal and individual-level resources associated with the onset of The Cedar Project looks at HIV and hepatitis C homelessness among vulnerably-housed individuals, and the vulnerabilities among Aboriginal young people who use attainment of stable housing among homeless individuals. injection or non-injection drugs. The community-based Additionally, they hope to determine the rate at which research initiative has sites in Vancouver, Prince George homeless individuals achieve residential stability and the and Chase, BC, and is the first indigenous “at risk” young rate at which vulnerably housed participants become people’s cohort in North America. homeless over a two-year follow-up. The study is scheduled to conclude in February 2014.

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Research Highlights continued martin dee photo/UBC Public affairs Public affairs dee photo/UBC martin photo courtesy of ubc public affairs courtesy photo

Dr. Karin Humphries received a new professorship this year. Dr. Larry Lynd will look at potential funding policies for treatment of rare diseases.

Heart research gets pumped up CORE researchers to analyze policies for rare disease treatment Dr. Karin Humphries received the UBC Heart and Stroke Foundation Professorship in Women’s Cardiovascular Health Collaboration for Outcomes Research and Evaluation in the fall of 2011, forming the first research program in (CORE) Associate Director Dr. Larry Lynd is leading a team British Columbia to focus on gender-based differences in of researchers to explore potential funding policies for cardiovascular disease. Dr. Karin Humphries will develop a treating rare diseases. Dr. Lynd and his team were given a focused and integrated vision for cardiovascular care, five-year grant through CIHR’s Emerging Team: Rare education and research for women throughout the Diseases – Health Services Program in April 2012. province, including rural communities. The professorship will be based at St. Paul’s Hospital. There are currently limited and costly treatment options for rare diseases that are far above average drug costs for Dr. Humphries will focus on researching the detection and common diseases. Dr. Lynd and his team will explore the early treatment of cardiovascular disease and finding new issue of how much public funding should be spent on drugs ways to improve the education of physicians, women and for these rare diseases, and develop sustainable drug their families on heart disease and stroke. She will also payment policies and incentives for pharmaceutical firms develop strategies to improve outcomes for women at highest to consider and adopt lower cost alternatives for treatment. risk, including Aboriginal and South Asian women and those Dr. Lynd serves on the Health Canada Scientific Advisory of poor socioeconomic status. Committee on Nonprescription Drugs.

CORE is a multidisciplinary group of researchers with expertise in pharmacoepidemiology, health economics, clinical pharmacy, health promotion and program evaluation research. Researchers and methodologists at CORE endeavour to provide evidence to maximize quality of life, and the economic and clinical benefits of drug therapy.

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Conferences and Educational Sessions

Clinical Research Professional Development

Michelle Jones, manager of CHÉOS’ Clinical Trials Support Unit, facilitates research education opportunities for the PHC research community.

As the PHCRI representative within N2: Network of Networks, Ms. Jones has made the following available to research staff throughout Providence Health Care: Standard Operating Procedures (SOPs) for Clinical Research; Collaborative Institutional Training Initiative (CITI) online training; and courses, including Good Clinical Practices, Responsible Conduct of Research for Life Sciences & Basic Biomedical Program. samantha jung photo/chÉOS Some of the workshops organized and hosted in 2011–2012 include: Drs. Chris Richardson and Michael Krausz at December’s E-Mental Health Conference.

• November 3, 2011, 9:00am to 12:00pm: Clinical Trial engaged in dialogue on how social media tools and the Budgets, presented by Pfizer Canada Clinical Operations Internet could be integrated into the current health care system. The conference included presenters from Canada, • November 4, 2011, 8:30am to 4:30pm: Investigator Switzerland and Germany. Training Program Workshop, hosted by Pfizer Canada

• December 13, 2011, 9:00am to 10:30am: Webinar – Whistler Winter Workshop on Mental FDA Safety Reporting Requirements for Clinical Trials: Health and Addiction Tips for Compliance Thirty researchers from eight countries participated in an • February 15, 2012, 9:00am to 10:30am: Webinar – Site interdisciplinary workshop on addictions research from Patient Recruitment Specialist: Is Your Site Ready? February 18–25, 2012 in Whistler, BC. The event was chaired by Dr. Michael Krausz. E-Mental Health Conference The participants discussed various scientific perspectives and current issues in the field of addiction research at the event. On December 12, 2011, the Addictions and Concurrent Disorders Group, led by Dr. Michael Krausz, hosted their first E-Mental Health Conference at Vancouver General Hospital.

Dr. Krausz was appointed the lead on the joint Bell Youth Mental Health IMPACT project a month prior to the conference, and attendees and presenters collaborated and

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Work in Progress Seminars samantha jung photo/chÉOS

Our Work in Progress seminars highlight research from all research disciplines.

Work in Progress (WiP) presentations take place at St. Paul’s Hospital in the Hurlburt Auditorium every second Wednesday from 12:00–1:00pm. These seminars provide investigators with an opportunity to present ongoing research, obtain feedback from colleagues and peers, and make new connections for their projects. A light lunch is served.

Below are the Work in Progress abstracts for the presentations that took place in 2011–2012.

September 28, 2011 October 12, 2011 Dr. Joel Singer: The methodological consultant cometh: Mohsen Sadatsafavi: Trends in asthma-related direct Navigating the clinician-researcher collaboration medical costs from 2002 to 2007 in British Columbia, Canada: A population-based cohort study using Abstract: Both the physician/laboratory researcher and the administrative health records methodological/statistical consultant come in various shapes and sizes and with different levels of expertise and familiarity Abstract: Asthma is a prevalent disease, and Canada ranks of each other’s areas. Dr. Joel Singer will discuss some of the very high in terms of the burden of asthma in the world. ways that both parties can make the best use of the Moreover, the inflow of new therapies and management collaboration based on many years of providing guidelines creates a dynamic picture for the burden of asthma consultation. Included among the topics discussed are in Canada. We have capitalized on the comprehensive, high preparing for the consultation, the language for exchanging quality health care resource use data of BC (Population BC information and following up in a way that there is Data) to estimate the direct health care costs and to assurance that the parties have understood one another. evaluate the trend of asthma-related resource use in the province. The analysis shows a rapidly changing pattern of resource use with important implications for policy makers. We will show the preliminary results and also discuss the certain methodological and conceptual challenges inherent in using administrative data in this context.

` `Centre for Health Evaluation and Outcome Sciences 20 Annual Report 2011–12

Work in Progress Seminars continued factors. These challenges will be discussed within the context of the Health and Housing in Transition Study, an ongoing observational longitudinal study of almost 1,200 October 26, 2011 homeless and vulnerably housed adults in Vancouver, Dr. Majid Al-Desouki: Mental health and addictions in the Toronto and Ottawa. Middle East: A transcultural perspective

Abstract: The medical management of mental health and November 23, 2011 addictions has come a long way over recent times and the Drs. Najib Ayas and Peter Dodek: Attributable morbidity stigma towards those with these conditions has and mortality of safety outcomes in ICUs diminished significantly over the decades. Nevertheless, there still remains a stigma towards mental health that Abstract: Improving patient safety in intensive care units presents as a significant barrier towards effective treatment. (ICUs) is an important priority. Several safety outcomes have This talk will touch on how these changes came about in become popular as targets for improvement but the the Middle East and how they evidently affected the current attributable morbidity and mortality of these outcomes is not perception of mental health and addictions with emphasis always clear. This presentation will describe several safety on the differences in contrast to North America. outcomes in critical care and will describe a multi-pronged quantitative approach to determining the attributable morbidity and mortality of clostridium difficile-associated November 9, 2011 diarrhea and bleeding while on anticoagulants. Dr. Stephen Hwang: Challenges in understanding the connections between housing and health: The Health and Housing in Transition Study January 18, 2012 Dr. Martha Mackay: Sex and gender differences in Abstract: Housing is an important social determinant of symptoms of myocardial ischemia health, but delineating the connections between the two can be difficult. Challenges include the unstable and fluctuating Abstract: Research has consistently shown that women housing status of marginalized populations, as well as delay seeking treatment for symptoms of acute coronary uncertainty regarding causal pathways and mediating syndrome (ACS) longer than do men (continued over).

` `Centre for Health Evaluation and Outcome Sciences 21 Annual Report 2011–12

Work in Progress Seminars continued February 29, 2012 Dr. Nick Bansback: Can we use ‘nudges’ to improve clinical Some research has indicated that women’s symptoms of decision-making? ACS are different from men’s, which could perhaps be an explanation for treatment-seeking delay. However, many Abstract: For many clinical cases, patient preferences are studies to date have had methodological flaws, rendering crucial in making appropriate health care decisions. Where conclusions tenuous. In this prospective study, we used benefits do not necessarily outweigh harms, choices usually balloon inflation during coronary angioplasty as a model hinge on trade-offs that only patients can decide on. In for myocardial ischemia, and questioned participants about recognition of this, decision aids have been developed to their symptoms during this period of known ischemia. help patients understand complex medical information so they can become informed and engage in shared decision- February 1, 2012 making. However, in decisions that are unfamiliar and Drs. Aslam Anis and Huiying Sun: Comparative effectiveness require the comprehension of a considerable amount of research and cost-effectiveness analysis: An overview and complicated information, psychology research has shown case study involving the treatment of psoriasis that people frequently make systematic errors that lead to poor choices. The term “nudge” was first used to describe Abstract: Comparative effectiveness research (CER) describes “any aspect of the choice architecture that alters people’s a range of methodologies that can be used to inform health behaviour in a predictable way without forbidding any care decisions by providing evidence on the effectiveness, options or significantly changing their economic incentives.” benefits and harms of different treatment options. Drs. Anis This research seeks to examine whether we can “nudge” and Sun will present one form of CER using indirect patients to overcome these errors, leading to more comparisons and a cost-effectiveness analysis of biologic appropriate decisions. therapies in psoriasis to illustrate how decisions can be informed in the absence of direct evidence. March 14, 2012 Dr. Peggy Simpson: Creating an evidence-based pathway February 15, 2012 for delirium Dr. Dean Regier: New concepts in discrete choice preference measurement: An application to drug Abstract: Delirium is the most common psychiatric treatments for juvenile idiopathic arthritis syndrome found in the general hospital setting. The development of delirium in general and postoperative Abstract: Stated preference discrete choice methods are delirium in particular has significant effects on length of increasingly used to quantify the personal utility associated hospitalization, cost of care, complications, morbidity, with health and health care. Recent advancements in mortality, and long term cognitive impairment. There is statistical techniques allow researchers to quantify good evidence that improved clinical practices can have a individual-specific utility, both for the recruited sample and significant impact. Delirium has a high incidence in surgical for different samples drawn from a population. There is, patients and can be predicted, prevented, identified however, a paucity of research aimed at improving the consistently and managed effectively with both precision of individual-level utility estimates. Using a pharmacological and non-pharmacological interventions. discrete choice experiment that examined parents’ This presentation provides an overview of the research preferences for drug treatments in juvenile idiopathic being conducted at St. Paul’s Hospital that examines current arthritis, this research explores incorporating a behavioral Providence Health Care practices related to the prediction, ‘choice certainty’ question into the discrete choice identification, and management of delirium in general and elicitation approach. The purpose of such an exercise is to cardiac surgery patients. use respondents’ choice certainty as a means to improve the precision and face validity of individual-level utility and willingness to pay estimates.

` `Centre for Health Evaluation and Outcome Sciences 22 Annual Report 2011–12

Work in Progress Seminars continued May 9, 2012 Dr. Amy Salmon: The BC Methadone Prescribing Study April 11, 2012 Drs. Verena Strehlau and Michelle Patterson: At Home/ Abstract: Across BC, people wishing to receive methadone Chez Soi: A multi-site, longitudinal trial for homelessness maintenance therapy (MMT) for the treatment of opiate and mental health dependence continue to encounter multiple barriers to care. Chief among these is the difficulty of finding a physician to Abstract: Verena Strehlau and her colleague Michelle provide access to this treatment. Very little research is Patterson (SFU) presented an overview and early findings of available to identify what motivates physicians to the At Home/Chez Soi study, which is an incorporate MMT into their practice, and what factors ongoing multi-centre, longitudinal randomized controlled physicians identify as being important in decisions to trial on homelessness and mental health, funded by the continue or abandon MMT as part of patient care. This Mental Health Commission of Canada (MHCC). Currently, presentation describes one effort to address this gap in all 490 Vancouver participants are recruited and 290 of knowledge: The British Columbia Methadone Prescribing them receive housing and support through the study. Study. This study explores the factors that impact BC’s MMT prescriber workforce and to understand more about how to support physicians who prescribe MMT, including issues of April 25, 2012 motivation, workload, physician retention, treatment Jill Woelfer: Homeless young people and technology: approaches, and professional development needs. Ordinary experiences, extraordinary circumstances

Abstract: Homeless young people, aged up to 30, have June 13, 2012 ordinary interactions with technology that are conditioned Dr. Karin Humphries: Sex differences in outcome after by the extraordinary circumstances of homelessness. In this transcatheter aortic valve replacement (TAVR) talk, Jill Woelfer gave an overview of four years of research investigating the experiences that homeless young people Abstract: Transcatheter aortic valve replacement (TAVR) is an have with information systems such as Facebook and effective alternative to surgical valve replacement in technologies such as mobile phones and music players. symptomatic patients with severe aortic stenosis, but the She concluded with work-in-progress findings from her impact of sex on outcomes remains unclear. Using data from dissertation research—a study of the role of music in the two of the largest centres in Canada performing TAVR, (St. lives of homeless young people in Seattle and Vancouver, Paul’s Hospital, Quebec Heart and Lung Institute in Laval) BC, and associations that may exist between music and outcomes (mortality/morbidity) by sex was presented and risk-taking behaviors. the implication of these findings were discussed.

` `Centre for Health Evaluation and Outcome Sciences 23 Annual Report 2011–12

CHÉOS and Social Media

This year, CHÉOS has increased its online presence and community engagement through various social media portals. Though the use of its Twitter, Facebook, and LinkedIn accounts, we are effectively able to present research to the scientific community and the public.

Twitter LinkedIn

CHÉOS joined Twitter in November 2011, under the handle CHÉOS has a company page on LinkedIn with 35 followers. @CHEOSNews. The account is used to share research, It is updated on a weekly basis. upcoming events and news about our scientists and related research around the world. CHÉOS attends and “live-tweets” events hosted and attended by our scientists and researchers. E-newsletter Currently @CHEOSNews has over 300 followers and 950 updates. This year, CHÉOS replaced its quarterly newsletter with a smaller-scale e-newsletter that is published every two weeks. The newsletter provides subscribers with more frequent Facebook updates and announcements. Individuals can subscribe to the newsletter on our website. CHÉOS created a Facebook page in November 2011. It provides news, updates, photos, and event information for its fans. The page currently has over 80 “likes.”

` `Centre for Health Evaluation and Outcome Sciences 24 Annual Report 2011–12

Hires and Departures

Recently Joined: Departures:

• Sindi Addorisio – Research Assistant, Study to Assist • Odette Bodman – Research Interviewer, Longer-Term Opiod Maintenance ACCEPT Study Effectiveness (SALOME) • Denise Bumby – Nurse, Cedar Project • Litsa Blanis – Project Manager, Collaboration for • Mercedes de la Caridad Dorrbercker Drake – Outcomes Research and Evaluation (CORE) Interviewer, Cedar Project • Melanie Di Menna – Research Assistant, Delirium • Ida Chan – Communications and Administrative Research Program Assistant, Addictions and Concurrent • Jesse Frender – Research Assistant, Health and Disorders Group Housing in Transition (HHiT) Study Team • Helen Dunham – Research Assistant, ICU • Jessica Galo – Research Coordinator, CORE Research Team • Lyanne Gaspard – Interviewer, Cedar Project • Janene Erickson – Interviewer, Cedar Project • Ladan Hamadani – Research Coordinator and Social • Jennifer Lee – Research Assistant, HHiT Team Media Consultant, BC Adolescence and • Janice Palmer – Research Interviewer, Advance Care Substance Use Survey Planning Evaluation in Elderly Patients Study • Samantha Jung – Communications Coordinator • Shannon Pidlubny – HHiT Team • Amir Khakban – Research Analyst, CORE • Laurel Slaney – Administrative Assistant for • Allison Laing – Research Assistant, Bell Project Women’s Heart Health and Research Assistant, SALOME • Rod Tomma – Interviewer, Cedar Project • Ruth Lavergne – Methodologist • Claire Volpe – Research Assistant/Interviewer, • Marissa Mar – Research Assistant, Addictions and HHiT Team Concurrent Disorders Group • Xu Wang – Research Assistant • Fatemeh (Tima) Mohammadi – Research Analyst, CORE • Stephen W. Pan – Data Management Assistant, Cedar Project • Lindsey Parsons – Interviewer, Cedar Project • Joseph Puyat – Methodologist • Tanisha Salomons – Interviewer, Cedar Project • Lindsay Seaby – Research Nurse, Cedar Project • Tyler Thompson – Communications and Administrative Assistant, Addictions and Concurrent Disorders Group • Zafar Zafari – Summer Student, CORE

` `Centre for Health Evaluation and Outcome Sciences 25 Annual Report 2011–12

Research Support Services

In addition to our research efforts, a primary focus of the centre is to provide methodological support to other researchers. Our outcomes-related research services help clinicians and researchers publish evidence-based academic papers on health outcomes and help them develop tools to obtain and analyze data. We have expanded our research services support staff in order to further this mandate to foster research initiatives. Joseph Puyat and Ruth Lavergne, both research methodologists, joined our team this year. Michelle Jones, our manager of clinical trials support, organizes educational seminars and workshops on clinical trial and research methods, and is a member of the Clinical Research Professional Development Group.

CHÉOS research services include: • Research study design

• Statistical support

• Database development and support

• Assistance with grants

• Mentoring

• Clinical trial protocol development including:

• Human resource needs assessment

• Budget planning

• Data form creation (paper or electronic)

• Study logistics

• Study document creation including informed consent form templates, standard operating procedures, study manuals and participant advertising

• Regulatory process and documentation

• Project management assessment

• Training for various tasks, such as clinical research regulations, investigator’s meetings and study procedures for clinical site personnel

• Study registration (L to R) Drs. Hubert Wong and Nadia Khan.

` `Centre for Health Evaluation and Outcome Sciences 26 Annual Report 2011–12

Key Contacts

Michelle Jones Kristin Westland Manager of Clinical Trials Director of Operations Support BA, MA RN, MSc(A), MBA [email protected] [email protected]

Tracey Chang Samantha Jung Program Coordinator Communications BBA Coordinator [email protected] BA [email protected] [email protected]

` `Centre for Health Evaluation and Outcome Sciences 27 Annual Report 2011–12

Appendices

I. Peer-Reviewed Journal Publications

II. Invited Presentations

III. Abstracts

` `Centre for Health Evaluation and Outcome Sciences 28 Appendix I

Appendix I: Peer-Reviewed Journal Publications

Abrahamyan L, Boom N, Donovan LR, Tu JV, Humphries K, Canadian Cardiovascular Society Quality Indicators Steering Committee. An international environmental scan of quality indicators for cardiovascular care. Canadian Journal of Cardiology. 2012 Jan-Feb; 28(1):110-8. EPub 2011 Dec 10. Review. PubMed PMID: 22154233.

Ahmadi N, McKenzie ME, Maclean A, Brown CJ, Mastracci T, McLeod RS and the Evidence-Based Reviews in Surgery Steering Group. Teaching evidence based medicine to surgery residents—is journal club the best format? A systematic review of the literature. Journal of Surgical Education. 2012 Jan-Feb; 69(1):91-100. Epub 2011 Oct 2. Review. PubMed PMID: 22208839.

Albarak J, Nijjar AP, Aymong E, Wang H, Quan H, Khan NA. Outcomes in young South Asian Canadians after acute myocardial infarction. Canadian Journal of Cardiology. 2012 Mar-Apr; 28(2):178-83. Epub 2012 Jan 11. PubMed PMID: 22244516.

Anis A, Harvard S, Marra C. Ontario’s plunging price-caps on generics: deeper dives may drown some drugs. Open Med. 2011; 5(3):e149-52. Epub 2011 Sep 27. Review. PubMed PMID: 22046229; PubMed Central PMCID: PMC3205826.

Anis AH, Bansback N, Sizto S, Gupta SR, Willian MK, Feldman SR. Economic evaluation of biologic therapies for the treatment of moderate to severe psoriasis in the United States. Journal of Dermatological Treatment. 2011 Apr; 22(2):65-74. PubMed PMID: 20443663.

Astor BC, Matsushita K, Gansevoort RT, van der Velde M, Woodward M, Levey AS, Jong PE, Coresh J; Chronic Kidney Disease Prognosis Consortium, l-Nahas M, Eckardt KU, Kasiske BL, Wright J, Appel L, Greene T, Levin A, Djurdjev O, Wheeler DC, Landray MJ, Townend JN, Emberson J, Clark LE, Macleod A, Marks A, Ali T, Fluck N, Prescott G, Smith DH, Weinstein JR, Johnson ES, Thorp ML, Wetzels JF, Blankestijn PJ, van Zuilen AD, Menon V, Sarnak M, Beck G, Kronenberg F, Kollerits B, Froissart M, Stengel B, Metzger M, Remuzzi G, Ruggenenti P, Perna A, Heerspink HJ, Brenner B, de Zeeuw D, Rossing P, Parving HH, Auguste P, Veldhuis K, Wang Y, Camarata L, Thomas B, Manley T. Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease: A collaborative meta-analysis of kidney disease population cohorts. Kidney International. 2011 Jun; s79(12):1331-40. PubMed PMID: 21289598.

Backmund M, Meyer K, Schütz C, Reimer J. Factors associated with suicide attempts among injection drug users. Substance Use & Misuse. 2011; 46(12):1553-9. Epub 2011 Apr 4. PubMed PMID: 21463204.

Baigent C, Landray MJ, Reith C, Emberson J, Wheeler DC, Tomson C, Wanner C, Krane V, Cass A, Craig J, Neal B, Jiang L, Hooi LS, Levin A, Agodoa L, Gaziano M, Kasiske B, Walker R, Massy ZA, Feldt- Rasmussen B, Krairittichai U, Ophascharoensuk V, Fellström B, Holdaas H, Tesar V, Wiecek A, Grobbee D, de Zeeuw D, Grönhagen-Riska C, Dasgupta T, Lewis D, Herrington W, Mafham M, Majoni W, Wallendszus K, Grimm R, Pedersen T, Tobert J, Armitage J, Baxter A, Bray C, Chen Y, Chen Z, Hill M, Knott C, Parish S, Simpson D, Sleight P, Young A, Collins R; SHARP Investigators. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. Lancet. 2011 Jun 25; 377(9784):2181-92. Epub 2011 Jun 12. PubMed PMID: 21663949; PubMed Central PMCID: PMC3145073.

` `Centre for Health Evaluation and Outcome Sciences 29 Appendix I

Baldwin C, Farah M, Leung M, Taylor P, Werb R, Kiaii M, Levin A. Multi-intervention management of calciphylaxis: a report of 7 cases. American Journal of Kidney Diseases. 2011 Dec; 58(6):988-91. Epub 2011 Aug 26. PubMed PMID: 21872378.

Bansback N, Brazier J, Tsuchiya A, Anis A. Using a discrete choice experiment to estimate health state utility values. Journal of Health Economics. 2012 Jan; 31(1):306-18. Epub 2011 Dec 6. PubMed PMID: 22197308.

Bansback N, Tsuchiya A, Brazier J, Anis A. Canadian valuation of EQ-5D health states: preliminary value set and considerations for future valuation studies. PLoS One. 2012; 7(2):e31115. Epub 2012 Feb 6. PubMed PMID: 22328929; PubMed Central PMCID: PMC3273479.

Bansback N, Zhang W, Walsh D, Kiely P, Williams R, Guh D, Anis A, Young A. Factors associated with absenteeism, presenteeism and activity impairment in patients in the first years of RA. Rheumatology (Oxford). 2012 Feb; 51(2):375-84. Epub 2011 Dec 16. PubMed PMID: 22179728.

Barbour SJ, Beaulieu MC, Zalunardo NY, Magil AB. Proliferative glomerulonephritis with monoclonal IgG deposits secondary to chronic lymphocytic leukemia: Report of two cases. Nephrology Dialysis Transplantation. 2011 Aug; 26(8):2712- 4. Epub 2011 Jun 1. PubMed PMID: 21633102.

Barbour SJ, Greenwald A, Djurdjev O, Levin A, Hladunewich MA, Nachman PH, Hogan SL, Cattran DC, Reich HN. Disease- specific risk of venous thromboembolic events is increased in idiopathic glomerulonephritis. Kidney International. 2012 Jan; 81(2):190-5. doi: 10.1038/ki.2011.312. Epub 2011 Sep 14. PubMed PMID: 21918501.

Barrett BJ, Garg AX, Goeree R, Levin A, Molzahn A, Rigatto C, Singer J, Soltys G, Soroka S, Ayers D, Parfrey PS. A nurse- coordinated model of care versus usual care for stage 3/4 chronic kidney disease in the community: a randomized controlled trial. Clinical Journal of the American Society of Nephrology. 2011 Jun; 6(6):1241-7. Epub 2011 May 26. PubMed PMID: 21617090; PubMed Central PMCID: PMC3109918.

Beaulieu S, Saury S, Sareen J, Tremblay J, Schütz CG, McIntyre RS, Schaffer A, Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force. The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid substance use disorders. Annals of Clinical Psychiatry. 2012 Feb; 24(1):38-55. Review. PubMed PMID: 22303521.

Bowker SL, Richardson K, Marra CA, Johnson JA. Risk of breast cancer after onset of type 2 diabetes: evidence of detection bias in postmenopausal women. Diabetes Care. 2011 Dec; 34(12):2542-4. Epub 2011 Oct 4. PubMed PMID: 21972408; PubMed Central PMCID: PMC3220847.

Brown CJ, Finlayson SR, Taylor MC, Evidence Based Reviews in Surgery Group. CAGS and ACS Evidence Based Reviews in Surgery Group: Access to emergency operative care: a comparative study between the Canadian and American health care systems. Canadian Journal of Surgery. 2011 Dec; 54(6):403-6. PubMed PMID: 22099318; PubMed Central PMCID: PMC3238339.

Chang P, Gill J, Dong J, Rose C, Yan H, Landsberg D, Cole EH, Gill JS. Living donor age and kidney alograft half-life: implications for living donor paired exchange programs. Clinical Journal of American Society of Nephrology. 2012 May; 7(5):835-41. Epub 2012 Mar 22. PubMed PMID: 22442187; PubMed Central PMCID: PMC3338279.

` `Centre for Health Evaluation and Outcome Sciences 30 Appendix I

Cheng L, Harris DR, Grafstein E. DTU’s improve patient care. Qmentum Quarterly. 2011; 3(4): 12–15.

Choi HK, Burns LC, Shojania K, Koenig N, Reid G, Abufayyah M, Law G, Kydd AS, Ouellette H, Nicolaou S. Dual energy CT in gout: a prospective validation study. Annals of Rheumatic Diseases. 2012 Mar 2. [Epub ahead of print] PubMed PMID: 22387729.

Choi M, Kim H, Qian H, Palepu A. Readmission rates of patients discharged against medical advice: a matched cohort study. PLoS One. 2011; 6(9):e24459. Epub 2011 Sep 8. PubMed PMID: 21931723; PubMed Central PMCID: PMC3169593.

Cibere J, Sayre EC, Guermazi A, Nicolaou S, Kopec JA, Esdaile JM, Thorne A, Singer J, Wong H. Natural history of cartilage damage and osteoarthritis progression on magnetic resonance imaging in a population-based cohort with knee pain. Osteoarthritis Cartilage. 2011 Jun; 19(6):683-8. PubMed PMID: 21329760.

Clement FM, Manns BJ, Brownell B, Faris PD, Graham MM, Humphries K, Love M, Knudtson ML, Ghali WA, APPROACH Investigators. A multi-region assessment of population rates of cardiac catheterization and yield of high-risk coronary artery disease. BMC Health Services Research. 2011 Nov 24; 11:323. PubMed PMID: 22115358; PubMed Central PMCID: PMC3252261.

Conley J, Tonelli M, Quan H, Manns BJ, Palacios-Derflingher L, Bresee LC, Khan N, Hemmelgarn BR; Alberta Kidney Disease Network. Association between GFR, proteinuria, and adverse outcomes among White, Chinese, and South Asian individuals in Canada. American Journal of Kidney Diseases. 2012 Mar; 59(3):390-9. Epub 2011 Nov 23. PubMed PMID: 22115883.

Crema MD, Guermazi A, Sayre EC, Roemer FW, Wong H, Thorne A, Singer J, Esdaile JM, Marra MD, Kopec JA, Nicolaou S, Cibere J. The association of magnetic resonance imaging (MRI)-detected structural pathology of the knee with crepitus in a population-based cohort with knee pain: the MoDEKO study. Osteoarthritis Cartilage. 2011 Dec; 19(12):1429-32. Epub 2011 Sep 13. PubMed PMID: 21945851.

Davis JC, Liu-Ambrose T, Khan KM, Robertson MC, Marra CA. SF-6D and EQ-5D result in widely divergent incremental cost- effectiveness ratios in a clinical trial of older women: implications for health policy decisions. Osteoporosis International. 2012 Jul; 23(7):1849-57. Epub 2011 Sep 10. PubMed PMID: 21909728.

Davis JC, Marra CA, Robertson MC, Najafzadeh M, Liu-Ambrose T. Sustained economic benefits of resistance training in community-dwelling senior women. Journal of the American Geriatrics Society. 2011 Jul; 59(7):1232-7. doi: 10.1111/j.1532-5415.2011.03474.x. Epub 2011 Jun 30. PubMed PMID: 21718265.

Dixon E, Cheadle WG, Khadaroo RG, Brown CJ; Members of the Evidence-Based Reviews in Surgery Group. Is chlorhexidine-alcohol more effective than povidone-iodine? Journal of the American College of Surgeons. 2012 Mar; 214(3):374-6. PubMed PMID: 22365506.

Dodek P, Chanques G, Brown G, Norena M, Grubisic M, Wong H, Jaber S. Role of organisational structure in implementation of sedation protocols: a comparison of Canadian and French ICUs. BMJ Quality and Safety. 2011 Aug 5. [Epub ahead of print] PubMed PMID: 21821629.

` `Centre for Health Evaluation and Outcome Sciences 31 Appendix I

Dodek PM, Norena M, Keenan SP, Teja A, Wong H. Intensive care unit admissions for community-acquired pneumonia are seasonal but are not associated with weather or reports of influenza-like illness in the community. Journal of Critical Care. 2011 Jun; 26(3):228-33. PubMed PMID: 21036532.

Dodek PM, Wong H, Jaswal D, Heyland DK, Cook DJ, Rocker GM, Kutsogiannis DJ, Dale C, Fowler R, Ayas NT. Organizational and safety culture in Canadian intensive care units: relationship to size of intensive care unit and physician management model. Journal of Critical Care. 2012 Feb; 27(1):11-7. Epub 2011 Sep 29. PubMed PMID: 21958984.

Fairbairn N, Milloy MJ, Zhang R, Lai C, Grafstein E, Kerr T, Wood E. Emergency department utilization among a cohort of HIV-positive injecting drug users in a Canadian setting. Journal of Emergency Medicine. 2011 Jun 28. [Epub ahead of print] PubMed PMID: 21719229; PubMed Central PMCID: PMC3189422.

Forbes JC, Alimenti AM, Singer J, Brophy JC, Bitnun A, Samson LM, Money DM, Lee TC, Lapointe ND, Read SE, Canadian Pediatric AIDS Research Group (CPARG). A national review of vertical HIV transmission. AIDS. 2012 Mar 27; 26(6):757-63. PubMed PMID: 22210635.

Garg AX, Meirambayeva A, Huang A, Kim J, Prasad GV, Knoll G, Boudville N, Lok C, McFarlane P, Karpinski M, Storsley L, Klarenbach S, Lam N, Thomas SM, Dipchand C, Reese P, Doshi M, Gibney E, Taub K, Young A, Gill J, Donor Nephrectomy Outcomes Research Network. Cardiovascular disease in kidney donors: matched cohort study. British Medical Journal. 2012 Mar 1; 344:e1203. doi: 10.1136/bmj.e1203. PubMed PMID: 22381674; PubMed Central PM CID: PMC3291749.

Geller J, Brown KE, Srikameswaran S. The efficacy of a brief motivational intervention for individuals with eating disorders: a randomized control trial. International Journal of Eating Disorders. 2011 Sep; 44(6):497-505. doi: 10.1002/eat.20847. PubMed PMID: 20872758.

Gill J, Sampaio M, Gill JS, Dong J, Kuo HT, Danovitch GM, Bunnapradist S. Induction immunosuppressive therapy in the elderly kidney transplant recipient in the United States. Clinical Journal of American Society of Nephrology. 2011 May; 6(5):1168-78. Epub 2011 Apr 21. PubMed PMID: 21511836; PubMed Central PMCID: PMC3087785.

Gill JS, Tonelli M. Penny wise, pound foolish? Coverage limits on immunosuppression after kidney transplantation. New England Journal of Medicine. 2012 Feb 16; 366(7):586-9. Epub 2012 Feb 1. PubMed PMID: 22296029.

Gill JS. Achieving fairness in access to kidney transplant: a work in progress. American Journal of Kidney Diseases. 2011 Nov; 58(5):697-9. PubMed PMID: 22014636.

Gill JS. Managing patients with a failed kidney transplant: how can we do better? Current Opinion in Nephrology & Hypertension. 2011 Nov; 20(6):616-21. Review. PubMed PMID: 21946163.

Gregory A, Walker I, McLaughlin K, Peets AD. Both preparing to teach and teaching positively impact learning outcomes for peer teachers. Medical Teacher. 2011; 33(8):e417-22. PubMed PMID: 21774637.

Grindrod KA, Lynd LD, Joshi P, Rosenthal M, Isakovic A, Marra CA. Pharmacy owner and manager perceptions of pharmacy adaptation services in British Columbia. Canadian Pharmacy Journal. 2011 Sep; 144(5):231-5. doi: http://www.cpjournal.ca/doi/abs/10.3821/1913-701X-144.5.231.

` `Centre for Health Evaluation and Outcome Sciences 32 Appendix I

Guo N, Marra CA, FitzGerald JM, Elwood RK, Anis AH, Marra F. Patient preference for latent tuberculosis infection preventive treatment: a discrete choice experiment. Value in Health. 2011 Sep-Oct; 14(6):937-43. Epub 2011 Jul 29. PubMed PMID: 21914516.

Harris KC, Anis AH, Crosby MC, Cender LM, Potts JE, Human DG. Economic evaluation of palivizumab in children with congenital heart disease: a Canadian perspective. Canadian Journal of Cardiology. 2011 Jul-Aug; 27(4):523.e11-5. Epub 2011 Jun 12. English, French. PubMed PMID: 21664100.

Harrison MJ, Bansback NJ, Marra CA, Drummond M, Tugwell PS, Boonen A. Valuing health for clinical and economic decisions: directions relevant for rheumatologists. Journal of Rheumatology. 2011 Aug; 38(8):1770-5. PubMed PMID: 21807800.

Henrich J, Boyd R, McElreath R, Gurven M, Richerson PJ, Ensminger J, Alvard M, Barr A, Barrett C, Bolyanatz A, Camerer CF, Cardenas JC, Fehr E, Gintis HM, Gil-White F, Gwako EL, Henrich N, Hill K, Lesorogol C, Patton JQ, Marlowe FW, Tracer DP, Ziker J. Culture does account for variation in game behavior. Proceedings of the National Academy of Science. 2012 Jan 10;109(2):E32-3; author reply E34. Epub 2012 Jan 4. PubMed PMID: 22219355; PubMed Central PMCID: PMC3258588.

Henrich N, Holmes B. Communicating during a pandemic: information the public wants about the disease and new vaccines and drugs. Health Promotion Practice. 2011 Jul; 12(4):610-9. PubMed PMID: 21059872.

Henrich N, Lynd LD, Joshi P, Grindrod K, Marra CA. Family physicians’ perceptions of pharmacy adaptation services in British Columbia. Can Pharm J. 2011; 144(4):172-8. doi: dx.doi.org/10.3821/1913-701X-144.4.172.

Henrich NJ, Dodek P, Heyland D, Cook D, Rocker G, Kutsogiannis D, Dale C, Fowler R, Ayas N. Qualitative analysis of an intensive care unit family satisfaction survey. Crit Care Med. 2011 May; 39(5):1000-5. PubMed PMID: 21283004.

Higgins J, Ye J, Humphries KH, Cheung A, Wood DA, Webb JG, Lichtenstein SV. Early clinical outcomes after transapical aortic valve implantation: a propensity-matched comparison with conventional aortic valve replacement. Journal of Thoracic and Cardiovascular Surgery. 2011 Aug; 142(2):e47- 52. Epub 2011 May 17. PubMed PMID: 21592530.

Hopkins RB, Garg AX, Levin A, Molzahn A, Rigatto C, Singer J, Soltys G, Soroka S, Parfrey PS, Barrett BJ, Goeree R. Cost- effectiveness analysis of a randomized trial comparing care models for chronic kidney disease. Clinical Journal of American Society of Nephrology. 2011 June; 6(6):1248-57. Epub 2011 May 26. PubMed PMID: 21617091; PubMed Central PMCID: PMC3109919.

Hwang SW, Aubry T, Palepu A, Farrell S, Nisenbaum R, Hubley AM, Klodawsky F, Gogosis E, Hay E, Pidlubny S, Dowbor T, Chambers C. The health and housing in transition study: a longitudinal study of the health of homeless and vulnerably housed adults in three Canadian cities. International Journal of Public Health. 2011 Dec; 56(6):609-23. Epub 2011 Aug 20. PubMed PMID: 21858461.

Ip S, Sayre EC, Guermazi A, Nicolaou S, Wong H, Thorne A, Singer J, Kopec JA, Esdaile JM, Cibere J. Frequency of bone marrow lesions and association with pain severity: results from a population-based symptomatic knee cohort. Journal of Rheumatology. 2011 Jun; 38(6):1079-85. PubMed PMID: 21362771.

` `Centre for Health Evaluation and Outcome Sciences 33 Appendix I

Isakova T, Gutiérrez OM, Patel NM, Andress DL, Wolf M, Levin A. Vitamin D deficiency, inflammation, and albuminuria in chronic kidney disease: complex interactions. Journal of Renal Nutrition. 2011 Jul; 21(4):295-302. PubMed PMID: 20817560.

Jackevicius CA, Tom A, Essebag V, Eisenberg MJ, Rahme E, Tu JV, Humphries K, Behlouli H, Pilote L. Population-level incidence and risk factors for pulmonary toxicity associated with amiodarone. American Journal of Cardiology. 2011 Sep 1; 108(5):705-10. Epub 2011 Jun 23. PubMed PMID: 21704281.

Januel JM, Couris CM, Luthi JC, Halfon P, Trombert-Paviot B, Quan H, Drosler S, Sundararajan V, Pradat E, Touzet S, Wen E, Shepheard J, Webster G, Romano PS, So L, Moskal L, Tournay-Lewis L, Sundaresan L, Kelley E, Klazinga N, Ghali WA, Colin C, Burnand B, International Methodology Consortium for Coded Health Information (IMECCHI); Finlayson A, Hemmelgarn B, De Coster C, Beck C, Carrière G, Johansen H, Tu J, Ma J, Humphries K, Fushimi K, Roos L, Lix L, Gao M, Jette N, Shrive F. ICD-10 adaptation of 15 Agency for Healthcare Research and Quality patient safety indicators. Revue d’Epidemiologie et de Sante Publiqu. 2011 Oct; 59(5):341-50. Epub 2011 Sep 6. French. PubMed PMID: 21899967.

Johnson JA, Bowker SL, Richardson K, Marra CA. Time-varying incidence of cancer after the onset of type 2 diabetes: evidence of potential detection bias. Diabetologia. 2011 Sep; 54(9):2263-71. Epub 2011 Jul 12. PubMed PMID: 21748485.

Joyce VR, Barnett PG, Chow A, Bayoumi AM, Griffin SC, Sun H, Holodniy M, Brown ST, Kyriakides TC, Cameron DW, Youle M, Sculpher M, Anis AH, Owens DK. Effect of treatment interruption and intensification of antiretroviral therapy on health-related quality of life in patients with advanced HIV: a randomized, controlled trial. Medical Decision Making. 2012 Jan-Feb; 32(1):70-82. PubMed PMID: 21383086.

Kiaii M, Djurdjev O, Farah M, Levin A, Jung B, MacRae J. Use of electron-beam sterilized hemodialysis membranes and risk of thrombocytopenia. Journal of the American Medical Association. 2011 Oct 19; 306(15):1679-87. PubMed PMID: 22009100.

King KM, Khan N, Leblanc P, Quan H. Examining and establishing translational and conceptual equivalence of survey questionnaires for a multi-ethnic, multi-language study. Journal of Advanced Nursing. 2011 Oct; 67(10):2267-74. doi: 10.1111/j.1365-2648.2011.05679.x. Epub 2011 Apr 29. PubMed PMID: 21535093.

Kozic JR, Benton SJ, Hutcheon JA, Payne BA, Magee LA, von Dadelszen P, Cundiff G, Preeclampsia Integrated Estimate of Risk Study Group. Abnormal liver function tests as predictors of adverse maternal outcomes in women with preeclampsia. Journal of Obstetrics and Gynaecology Canada. 2011 Oct; 33(10):995-1004. PubMed PMID: 22014776.

Kraemer M, Horn PA, Roder C, Khan N, Diehl RR, Berlit P, Heinemann FM. Analysis of human leukocyte antigen genes in Caucasian patients with idiopathic MoyaMoya angiopathy. Acta Neurochirurgica (Wien). 2012 Mar; 154(3):445-54. PubMed PMID: 22234791.

Lai EJ, Grubisic M, Palepu A, Quan H, King KM, Khan NA. Cardiac medication prescribing and adherence after acute myocardial infarction in Chinese and South Asian Canadian patients. BMC Cardiovascular Disorders. 2011 Sep 18; 11:56. PubMed PMID: 21923931; PubMed Central PMCID: PMC3189887.

` `Centre for Health Evaluation and Outcome Sciences 34 Appendix I

Lam N, Huang A, Feldman LS, Gill JS, Karpinski M, Kim J, Klarenbach SW, Knoll GA, Lentine KL, Nguan CY, Parikh CR, Prasad GV, Treleaven DJ, Young A, Garg AX, for the Donor Nephrectomy Outcomes Research (DONOR) Network. Acute dialysis risk in living kidney donors. Nephrology, Dialysis, Transplantation. 2012 Jan 30. [Epub ahead of print] PubMed PMID: 22290988.

Lear SA, Chockalingam A, Kohli S, Richardson CG, Humphries KH. Elevation in cardiovascular disease risk in South Asians is mediated by differences in visceral adipose tissue. Obesity (Silver Spring). 2012 Jan 26; doi:10.1038/oby.2011.395. [Epub ahead of print] PubMed PMID: 22282045.

Leichtman A, Abecassis M, Barr M, Charlton M, Cohen D, Confer D, Cooper M, Danovitch G, Davis C, Delmonico F, Dew MA, Garvey C, Gaston R, Gill J, Gillespie B, Ibrahim H, Jacobs C, Kahn J, Kasiske B, Kim J, Lentine K, Manyalich M, Medina-Pestana J, Merion R, Moxey-Mims M, Odim J, Opelz G, Orlowski J, Rizvi A, Roberts J, Segev D, Sledge T, Steiner R, Taler S, Textor S, Thiel G, Waterman A, Williams E, Wolfe R, Wynn J, Matas AJ. Living Kidney Donor Follow-Up Conference Writing Group. Living kidney donor follow-up: state-of-the-art and future directions, conference summary and recommendations. American Journal of Transplantation. 2011 Dec; 11(12):2561-8. doi: 10.1111/j.1600-6143.2011.03816.x. Epub 2011 Nov 4. PubMed PMID: 22054039.

Levin A, Beaulieu MC. Trials and tribulations of new agents, novel biomarkers, and retarding renal progression. Journal of American Society of Nephrology. 2011 Jun; 22(6):992-3. Epub 2011 May 26. PubMed PMID: 21617124.

Levin A, Le Barbier M, Er L, Andress D, Sigrist MK, Djurdjev O. Incident isolated 1,25(OH)(2)D(3) deficiency is more common than 25(OH)D deficiency in CKD. Journal of Nephrology. 2012 Mar-Apr; 25(2):204-10. doi: 10.5301/JN.2011.8429. PubMed PMID: 21688248.

Levin A, Stevens PE. Early detection of CKD: the benefits, limitations and effects on prognosis. Nature Reviews Nephrology. 2011 Jun 28; 7(8):446-57. doi: 10.1038/nrneph.2011.86. Review. PubMed PMID: 21712852.

Levin A. Nondialysis chronic kidney disease in 2011: Progression, prediction, populations and possibilities. Nature Reviews Nephrology. 2011 Dec 6; 8(2):70-2. doi: 10.1038/nrneph.2011.195. PubMed PMID: 22143330.

Lin RJ, Krall R, Westerberg BD, Chadha NK, Chau JK. Systematic review and meta-analysis of the risk factors for sudden sensorineural hearing loss in adults. Laryngoscope. 2012 Mar; 122(3):624-35. doi: 10.1002/lary.22480. Epub 2012 Jan 17. Review. PubMed PMID: 22252719.

Macentee MI, Kazanjian A, Kozak JF, Hornby K, Thorne S, Kettratad-Pruksapong M. A scoping review and research synthesis on financing and regulating oral care in long-term care facilities. Gerodontology. 2012 Jun; 29(2):e41-e52. doi: 10.1111/j.1741-2358.2011.00575.x. Epub 2011 Nov 20. PubMed PMID: 22098091.

Mackay MH, Ratner PA, Johnson JL, Humphries KH, Buller CE. Gender differences in symptoms of myocardial ischaemia. European Heart Journal. 2011 Dec; 32(24):3107-14. Epub 2011 Sep 14. PubMed PMID: 21920968.

Marchand K, Oviedo-Joekes E, Guh D, Marsh DC, Brissette S, Schechter MT. Sex work involvement among women with long-term opioid injection drug dependence who enter opioid agonist treatment. Harm Reduction Journal. 2012 Jan 25; 9(1):8. PubMed PMID: 22276954; PubMed Central PMCID: PMC3281790.

` `Centre for Health Evaluation and Outcome Sciences 35 Appendix I

Marchand KI, Oviedo-Joekes E, Guh D, Brissette S, Marsh DC, Schechter MT. Client satisfaction among participants in a randomized trial comparing oral methadone and injectable diacetylmorphine for long-term opioid-dependency. BMC Health Services Research. 2011 Jul 26; 11:174. PubMed PMID: 21791093; PubMed Central PMCID: PMC3161847.

Marra CA, Lynd LD, Colley L, Harvard SS, Lacaille D, Schwenger E, Anis AH, Esdaile JM. Risk of gastrointestinal events in patients with rheumatoid arthritis after withdrawal of rofecoxib. Journal of Rheumatology. 2012 May; 39(5):910-5. Epub 2012 Mar 15. PubMed PMID: 22422500.

Marra F, Marra CA, Richardson K, Lynd LD, Fitzgerald MJ. Antibiotic consumption in children prior to diagnosis of asthma. BMC Pulmonary Medicine. 2011 May 31; 11:32. PubMed PMID: 21627795; PubMed Central PMCID: PMC3118389.

Marshall BD, Grafstein E, Buxton JA, Qi J, Wood E, Shoveller JA, Kerr T. Frequent methamphetamine injection predicts emergency department utilization among street-involved youth. Public Health. 2012 Jan; 126(1):47-53. Epub 2011 Nov 30. PubMed PMID: 22133669; PubMed Central PMCID: PMC3246028.

Mehrotra A, Rose C, Pannu N, Gill J, Tonelli M, Gill JS. Incidence and consequences of acute kidney injury in kidney transplant recipients. American Journal of Kidney Diseases. 2012 Apr; 59(4):558- 65. Epub 2012 Jan 5. PubMed PMID: 22226565.

Mehta S, Granton J, Lapinsky SE, Newton G, Bandayrel K, Little A, Siau C, Cook DJ, Ayers D, Singer J, Lee TC, Walley KR, Storms M, Cooper J, Holmes CL, Hebert P, Gordon AC, Presneill J, Russell JA, Vasopressin and Septic Shock Trial (VASST) Investigators. Agreement in electrocardiogram interpretation in patients with septic shock. Critical Care Medicine 39:2080-2086. 2011 Sep; 39(9):2080-6. PubMed PMID: 21849822.

Mendelssohn D, Beaulieu M, Kiaii M, Jindal K, MacRae J, Kappel J, Miller L, Lok C, Moist L, Donnelly S, Oliver M, Chan C, Ethier J, Delziel C, McKinnon M, Soroka S, Hirsch D, Barrett B. Report of the Canadian Society of Nephrology Vascular Access Working Group. Seminars in Dialysis. 2012 Jan-Feb; 25(1):22-25. doi: 10.1111/j.1525-139X.2011.01009.x.

Miller CL, Pearce ME, Moniruzzaman A, Thomas V, Christian W, Schechter MT, Spittal PM, The Cedar Project Partnership. The Cedar Project: risk factors for transition to injection drug use among young, urban Aboriginal people. Canadian Medical Association Journal. 2011 Jul 12; 183(10):1147-54. Epub 2011 Jun 13. PubMed PMID: 21670106; PubMed Central PMCID: PMC3134722.

Mills EJ, Bansback N, Ghement I, Thorlund K, Kelly S, Puhan MA, Wright J. Multiple treatment comparison meta-analyses: a step forward into complexity. Clinical Epidemiology. 2011; 3:193-202. Epub 2011 May 27. PubMed PMID: 21750628; PubMed Central PMCID: PMC3130904.

Mills EJ, Kanters S, Hagopian A, Bansback N, Nachega J, Alberton M, Au-Yeung CG, Mtambo A, Bourgeault IL, Luboga S, Hogg RS, Ford N. The financial cost of doctors emigrating from sub- Saharan Africa: human capital analysis. British Medical Journal. 2011 Nov 23; 343:d7031. doi: 10.1136/bmj.d7031. PubMed PMID: 22117056; PubMed Central PMCID: PMC3223532.33.

` `Centre for Health Evaluation and Outcome Sciences 36 Appendix I

Morales-Manrique CC, Palepu A, Castellano-Gómez M, Aleixandre-Benavent, R, Comunidad Valenciana CG,Valderrama- Zurián JC. Quality of life and life areas with change potential among cocaine users: The role of lifetime severity addiction to cocaine. Substance Use and Misuse. 2011 Feb; 46(4): 390-7. PMID: 20735213.

Muroi C, Khan N, Bellut D, Fujioka M, Yonekawa Y. Extracranial-intracranial bypass in atherosclerotic cerebrovascular disease: report of a single centre experience. British Journal of Neurosurgery. 2011 Jun; 25(3):357-62. Epub 2011 Apr 18. PubMed PMID: 21501047.

Najafzadeh M, Lynd LD, Davis JC, Bryan S, Anis A, Marra M, Marra CA. Barriers to integrating personalized medicine into clinical practice: a best-worst scaling choice experiment. Genetics in Medicine. 2012 May; 14(5):520-6. doi: 10.1038/gim.2011.26. Epub 2012 Jan 26. PubMed PMID: 22241089.

Nikiphorou E, Guh D, Bansback N, Zhang W, Dixey J, Williams P, Young A. Work disability rates in RA. Results from an inception cohort with 24 years follow-up. Rheumatology (Oxford). 2012 Feb; 51(2):385-92. Epub 2012 Jan 11. PubMed PMID: 22237045.

Nordbø RH, Espeset EM, Gulliksen KS, Skårderud F, Geller J, Holte A. Reluctance to recover in anorexia nervosa. European Eating Disorders Review. 2012 Jan; 20(1):60-7. doi: 10.1002/erv.1097. PubMed PMID: 21305676.

Nosyk B, Guh DP, Bansback NJ, Oviedo-Joekes E, Brissette S, Marsh DC, Meikleham E, Schechter MT, Anis AH. Cost- effectiveness of diacetylmorphine versus methadone for chronic opioid dependence refractory to treatment. Canadian Medical Association Journal. 2012 Apr 3; 184(6):E317-28. Epub 2012 Mar 12. PubMed PMID: 22410375; PubMed Central PMCID: PMC3314060.

Nosyk B, Guh DP, Sun H, Oviedo-Joekes E, Brissette S, Marsh DC, Schechter MT, Anis AH. Health-related quality of life trajectories of patients in opioid substitution treatment. Drug and Alcohol Dependence. 2011 Nov 1; 118(2-3):259- 64. Epub 2011 May 4. PubMed PMID: 21546173.

Nosyk B, Sharif B, Sun H, Cooper C, Anis AH, CIHR Canadian HIV Trials Network Influenza Vaccine Research Group. The cost-effectiveness and value of information of three influenza vaccination dosing strategies for individuals with human immunodeficiency virus. PLoS One. 2011; 6(12):e27059. Epub 2011 Dec 6. PubMed PMID: 22162988; PubMed Central PMCID: PMC3232195.

Okoli C, Torchalla I, Oliffe J, Bottorff J. Men’s smoking cessation interventions: A brief review. Journal of Men’s Health. 8.2 (2011): 100 - 108. doi: 10.1016/j.jomh.2011.03.003.

Oviedo-Joekes E, Marsh DC, Guh D, Brissette S, Schechter MT. Potency ratio of hydromorphone and diacetylmorphine in substitution treatment for long-term opioid dependency. Journal of Opioid Management. 2011 Sep-Oct; 7(5):371-6. PubMed PMID: 22165036.

Palepu A, Milloy MJ, Kerr T, Zhang R, Wood E. Homelessness and adherence to antiretroviral therapy among a cohort of HIV- infected injection drug users. Journal of Urban Health. 2011 Jun; 88(3):545-55. PubMed PMID: 21409604; PubMed Central PMCID: PMC3126933.

Peets A, Ayas NT. Restricting resident work hours: the good, the bad, and the ugly. Critical Care Medicine. 2012 Mar; 40(3):960-6. Review. PubMed PMID: 22297631.

` `Centre for Health Evaluation and Outcome Sciences 37 Appendix I

Phang PT, Gollub MJ, Loh BD, Nash GM, Temple LK, Paty PB, Guillem JG, Weiser MR. Accuracy of endorectal ultrasound for measurement of the closest predicted radial mesorectal margin for rectal cancer. Diseases of the Colon & Rectum. 2012 Jan; 55(1):59-64. PubMed PMID: 22156868.

Phang PT, Woods R, Brown CJ, Raval M, Cheifetz R, Kennecke H. Effect of systematic education courses on rectal cancer treatments in a population. American Journal of Surgery. 2011 May; 201(5):640- 4. PubMed PMID: 21545914.

Phillips JS, Westerberg B. Intratympanic steroids for Ménière’s disease or syndrome. Cochrane Database Systematic Reviews. 2011 Jul 6; (7):CD008514. Review. PubMed PMID: 21735432.

Querido JS, Sheel AW, Cheema R, Van Eeden S, Mulgrew AT, Ayas NT. Effects of 10 days of modest intermittent hypoxia on circulating measures of inflammation in healthy humans. Sleep Breath. 2011 Jul 9; [Epub ahead of print] PubMed PMID: 21743982.

Rabi DM, Daskalopoulou SS, Padwal RS, Khan NA, et al; Canadian Hypertension Education Program. The 2011 Canadian 35 Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Canadian Journal of Cardiology. 2011 Jul-Aug; 27(4):415-433.e1-2. English, French. PubMed PMID: 21801975.

Rajan T, Barbour SJ, White CT, Levin A. Low birth weight and nephron mass and their role in the progression of chronic kidney disease: a case report on identical twins with Alport disease. Nephrology Dialysis Transplantation. 2011 Dec; 26(12):4136-9. Epub 2011 May 12. PubMed PMID: 21565948.

Raymakers AJ, Sadatsafavi M, Marra F, Marra CA. Economic and humanistic burden of external genital warts. PharmacoEconomics. 2012 Jan; 30(1):1-16. doi: 10.2165/11591170-000000000-00000. Review. PubMed PMID: 22201520.

Raynauld JP, Martel-Pelletier J, Haraoui B, Choquette D, Dorais M, Wildi LM, Abram F, Pelletier JP, Shojania K, Canadian Licofelone Study Group. Risk factors predictive of joint replacement in a two-year multicentre clinical trial in knee osteoarthritis using MRI: results from over six years of observation. Annals of Rheumatic Diseases. 2011 Aug; 70(8):1382-8. Epub 2011 May 8. PubMed PMID: 21551506.

Reimer-Kirkham S, Sharma S, Pesut B, Sawatzky R, Meyerhoff H, Cochrane M. Sacred spaces in public places: Religious and spiritual plurality in healthcare. Nursing Inquiry. 2012 Sep; 19(3):202-12. doi: 10.1111/j.1440-1800.2011.00571.x. Epub 2011 Aug 4. PubMed PMID: 22272739.

Richardson CG, Memetovic J, Ratner PA, Johnson JL. Examining gender differences in emerging tobacco use using the Adolescents’ Need For Smoking Scale. Addiction. 2011 Oct; 106(10):1846-54. doi: 10.1111/j.1360-0443.2011.03496.x. Epub 2011 Aug 9. PubMed PMID: 21561502.

Routy JP, Tremblay CL, Angel JB, Trottier B, Rouleau D, Baril JG, Harris M, Trottier S, Singer J, Chomont N, Sékaly RP, Boulassel MR. Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study. HIV Medicine. 2012 May; 13(5):291-6. doi: 10.1111/j.1468-1293.2011.00975.x. Epub 2012 Jan 26. PubMed PMID: 22276680.36.

Ruan Y, Pan SW, Chamot E, Qian HZ, Li D, Li QC, Liang HY, Spittal P, Shao Y, Kristensen S. Sexual mixing patterns among social networks of HIV-positive and HIV-negative Beijing men who have sex with men: a multilevel comparison

` `Centre for Health Evaluation and Outcome Sciences 38 Appendix I

using roundtable network mapping. AIDS Care. 2011 Aug; 23(8):1014-25. Epub 2011 Jul 7. PubMed PMID: 21400315.

Sawatzky RG, Ratner PA, Richardson CG, Washburn C, Sudmant W, Mirwaldt P. Stress and depression in students: the mediating role of stress management self-efficacy. Nursing Research. 2012 Jan-Feb; 61(1):13-21. PubMed PMID: 22166906.

Sawatzky R, Ratner PA, Kopec JA, & Zumbo, BD. Latent variable mixture models: A promising approach for the validation of patient reported outcomes. Quality of Life Research. 21(4), pp. 637-350. doi: 10.1007/s11136-011-9976-6.

Schechter MT, Kendall P. Is there a need for heroin substitution treatment in Vancouver’s Downtown Eastside? Yes there is, and in many other places too. Canadian Journal of Public Health 2011. 2011 Mar-Apr; 102(2):87-9. PubMed PMID: 21608377.

Scheuermeyer FX, Grafstein E, Heilbron B, Innes G. Emergency department management and one-year outcomes of patients with atrial flutter. Annals of Emergency Medicine. 2011 Jun; 57(6):564-571. e2. PubMed PMID: 21257230.

Scheuermeyer FX, Innes G, Grafstein E, Kiess M, Boychuk B, Yu E, Kalla D, Christenson J. Safety and efficiency of a chest pain diagnostic algorithm with selective outpatient stress testing for emergency department patients with potential ischemic chest pain. Annals of Emergency Medicine. 2012 Apr; 59(4):256-264.e3. Epub 2012 Jan 4. PubMed PMID: 22221842.

Schmitz T, Blaickner M, Ziegner M, Bassler N, Grunewald C, Kratz JV, Schütz C, Langguth P, Sharpe P, Palmans H, Holzscheiter MH, Otto G, Hampel G. Dose determination using alanine detectors in a mixed neutron and gamma field for boron neutron capture therapy of liver malignancies. Acta Oncologica. 2011 Aug; 50(6):817-22. PubMed PMID: 21767179.

Schütz C, Hoves S, Halbritter D, Zhang HG, Mountz JD, Fleck M. Alloantigen specific deletion of primary human T cells by Fas ligand (CD95L)-transduced monocyte-derived killer-dendritic cells. Immunology. 2011 May; 133(1):115-22. doi: 10.1111/j.1365-2567.2011.03417.x. PubMed PMID: 21342185; PubMed Central PMCID: PMC3088973.

Southern DA, Izadnegahdar M, Humphries KH, Gao M, Wang F, Knudtson ML, Graham MM, Ghali WA. Trends in wait times for cardiac revascularization. Canadian Journal of Cardiology. 2011 Mar-Apr; 27(2):262.e21-7. Erratum in: Canadian Journal of Cardiology. 2011 Sep- 37 Oct; 27(5):663. Izadneghadar, Mona [corrected to Izadnegahdar, Mona]. PubMed PMID: 21459277.

Steele SR, Kumar R, Feingold DL, Rafferty JL, Buie WD, Phang PT; Standards Practice Task Force of the American Society of Colon and Rectal Surgeons. Practice parameters for the management of perianal abscess and fistula-in-ano. Diseases of the Colon & Rectum. 2011 Dec; 54(12):1465-74. PubMed PMID: 22067173.

Sud S, Mittmann N, Cook DJ, Geerts W, Chan B, Dodek P, Gould MK, Guyatt G, Arabi Y, Fowler RA; Canadian Critical Care Trials Group; E-PROTECT Investigators. Screening and prevention of venous thromboembolism in critically ill patients: a decision analysis and economic evaluation. American Journal of Respiratory and Critical Care Medicine. 2011 Dec 1; 184(11):1289-98. Epub 2011 Aug 25. PubMed PMID: 21868500.

` `Centre for Health Evaluation and Outcome Sciences 39 Appendix I

Taffé P, Halfon P, Ghali WA, Burnand B, Humphries K; International Methodology Consortium for Coded Health Information (IMECCHI). Test result-based sampling: an efficient design for estimating the accuracy of patient safety indicators. Medical Decision Making. 2012 Jan-Feb; 32(1):E1-12. Epub 2011 Nov 7. PubMed PMID: 22065144.

Tang K, Escorpizo R, Beaton DE, Bombardier C, Lacaille D, Zhang W, Anis AH, Boonen A, Verstappen SM, Buchbinder R, Osborne RH, Fautrel B, Gignac MA, Tugwell PS. Measuring the impact of arthritis on worker productivity: perspectives, methodologic issues, and contextual factors. The Journal of Rheumatology. 2011 Aug; 38(8):1776-90. PubMed PMID: 21807801.

Tangri N, Stevens LA, Griffith J, Tighiouart H, Djurdjev O, Naimark D, Levin A, Levey AS. A predictive model for progression of chronic kidney disease to kidney failure. Journal of the American Medical Association. 2011 Apr 20; 305(15):1553-9. Epub 2011 Apr 11. PubMed PMID: 21482743.

Torchalla I, Okoli C, Malchy L, Johnson J. Nicotine dependence and gender differences in smokers accessing community mental health services. Journal of Psychiatric and Mental Health Nursing. 2011 May; 18.4 (2011): 349 - 358. doi: 10.1111/j.1365-2850.2010.01674.x.

Torchalla I, Nosen L, Rostam H, Allen P. Integrated treatment programs for individuals with concurrent substance use disorders and trauma experiences: a systematic review and meta-analysis. Journal of Substance Abuse Treatment. 2012 Jan; 42(1):65-77. Epub 2011 Oct 27. Review. Erratum in: J Subst Abuse Treat. 2012 Apr; 42(3):337. PubMed PMID: 22035700.38.

Torchalla I, Okoli C, Hemsing N, Greaves L. Gender differences in smoking behaviour and cessation. The Journal of Smoking Cessation. 6.1 (2011): 9-16. doi: http://dx.doi.org/10.1375/jsc.6.1.9.

Torchalla I, Strehlau V, Li K, Krausz M. Substance use and predictors of substance dependence in homeless women. Drug and Alcohol Dependence. 2011 Nov 1; 118(2-3):173-9. Epub 2011 Apr 16. PubMed PMID: 21498010.

Torchalla I, Strehlau V, Okoli C, Li K, Schutz C, Krausz M. Smoking and predictors of nicotine dependence in a homeless population. Nicotine & Tobacco Research. 2011 Oct; 13(10):934-42. Epub 2011 May 26. 13.10 (2011): 934–942. PubMed PMID: 21622493. doi: 10.1111/j.1365-2850.2010.01674.x

Tosh J, Brennan A, Wailoo A, Bansback N. The Sheffield rheumatoid arthritis health economic model. Rheumatology (Oxford). 2011 Sep; 50 Suppl 4:iv26-31. PubMed PMID: 21859702.

Tsadok MA, Jackevicius CA, Rahme E, Essebag V, Eisenberg MJ, Humphries KH, Tu JV, Behlouli H, Joo J, Pilote L. Amiodarone-induced thyroid dysfunction: brand-name versus generic formulations. Canadian Medical Association Journal. 2011 Sep 6; 183(12):E817-23. Epub 2011 Jul 11. PubMed PMID: 21746822; PubMed Central PMCID: PMC3168665.

Tsuda H, Lowe AA, Chen H, Fleetham JA, Ayas NT, Almeida FR. The relationship between mouth opening and sleep stage- related sleep disordered breathing. J Clin Sleep Med. 2011 Apr 15; 7(2):181-6. PubMed PMID: 21509334; PubMed Central PMCID: PMC3077347.

Udell JA, Wang CS, Tinmouth J, FitzGerald JM, Ayas NT, Simel DL, Schulzer M Mak E, Yoshida EM. Does this patient with liver disease have cirrhosis? Journal of the American Medical Association. 2012 Feb 22; 307(8):832-842. doi:10.1001/jama.2012.186.

` `Centre for Health Evaluation and Outcome Sciences 40 Appendix I

Vaghri Z, Wong H, Barr SI, Chapman GE, Hertzman C. Associations of socio-demographic and behavioral variables with hair zinc of Vancouver preschoolers. Biological Trace Element Research. 2011 Dec; 143(3):1398-412. PubMed PMID: 21369714.

Voth J, Sawatzky R, Ratner PA, Young ML, Repta R, Haines-Saah R, Johnson JL. A computer-assisted approach to filtering large numbers of documents for media analyses. International Journal of Social Research Methodology. 2012 Jan 1. Epub 2012 Jan 3. doi: 10.1080/13645579.2011.645700.

Walker RL, Chen G, Campbell NR, McAlister FA, Quan H, Tu K, Khan NA, Hemmelgarn BR, Canadian Hypertension Education Program Outcomes Research Task Force. Canadian provincial trends in antihypertensive drug prescriptions between 1996 and 2006. Canadian Journal of Cardiology. 2011 Jul-Aug; 27(4):461-7. Epub 2011 Jun 2. English, French. PubMed PMID: 21640546.39.

Wang M, Fitzgerald JM, Richardson K, Marra CA, Cook VJ, Hajek J, Elwood RK, Bowie WR, Marra F. Is the delay in diagnosis of pulmonary tuberculosis related to exposure to fluoroquinolones or any antibiotic? International Journal of Tuberculosis and Lung Disease. 2011 Aug; 15(8):1062- 8. PubMed PMID: 21740669.

Weber C, Beaulieu M, Djurdjev O, Er L, Taylor P, Ignaszewski A, Burnett S, Levin A. Towards rational approaches of health care utilization in complex patients: an exploratory randomized trial comparing a novel combined clinic to multiple specialty clinics in patients with renal disease-cardiovascular disease-diabetes. Nephrology Dialysis Transplantation. 2011 Jun 30. PubMed PMID: 21719715.

Weber CL, Bennett M, Er L, Bennett MT, Levin A. Urinary NGAL levels before and after coronary angiography: a complex story. Nephrology Dialysis Transplantation. 2011 Oct; 26(10):3207-11. PubMed PMID: 21355066.

Wilby K, Marra CA, da Silva JH, Grubisic M, Harvard S, Lynd LD. Randomized controlled trial evaluating pictogram augmentation of HIV medication information. The Annals of Pharmacotherapy. 2011 Nov; 45(11):1378-83. Epub 2011 Oct 25. PubMed PMID: 22028420.

Wölwer W, Frommann N, Jänner M, Franke PE, Scherbaum N, Lieb B, Falkai P, Wobrock T, Kuhlmann T, Radermacher M, Maier W, Schütz C, Ohmann C, Burtscheidt W, Gaebel W. The effects of combined acamprosate and integrative behaviour therapy in the outpatient treatment of alcohol dependence: a randomized controlled trial. Drug and Alcohol Dependence. 2011 Nov 1; 118(2-3):417-22. Epub 2011 May 31. PubMed PMID: 21621929.

Woolcott J, Khan K, Mitrovic S, Anis A, Marra CA. The cost of fall related presentations to the ED: A prospective, in-person, patient-tracking analysis of health resource utilization. Osteoporosis International. 2011 Sep 3; DOI: 10.1007/s00198-011- 1764-1 Epub 2011 Sep 3. PubMed PMID: 21892675.

Young A, Hodsman AB, Boudville N, Geddes C, Gill J, Goltzman D, Jassal SV, Klarenbach S, Knoll G, Muirhead N, Prasad GV, Treleaven D, Garg AX, Donor Nephrectomy Outcomes Research (DONOR) Network. Bone and mineral metabolism and fibroblast growth factor 23 levels after kidney donation. American Journal of Kidney Diseases. 2012 Jun; 59(6):761-9. Epub 2011 Nov 16. PubMed PMID: 22093959.

Zhang W, Bansback N, Boonen A, Severens JL, Anis AH. Development of a composite questionnaire, the valuation of lost productivity, to value productivity losses: application in rheumatoid arthritis. Value in Health. 2012 Jan; 15(1):46-54. Epub 2011 Oct 1. PubMed PMID: 22264971.

` `Centre for Health Evaluation and Outcome Sciences 41 Appendix I

Zhang W, Bansback N, Kopec J, Anis AH. Measuring time input loss among patients with rheumatoid arthritis: validity and reliability of the Valuation of Lost Productivity questionnaire. Journal of Occupational and Environmental Medicine. 2011 May; 53(5):530-6. PubMed PMID: 21508868.

Zhang W, Sun H, Emery P, Sato R, Singh A, Freundlich B, Anis AH. Does achieving clinical response prevent work stoppage or work absence among employed patients with early rheumatoid arthritis? Rheumatology (Oxford). 2012 Feb; 51(2):270-4. Epub 2011 Jun 29. PubMed PMID: 21719418.

Zakrzewski PA, Mackenzie PJ, Tsai G, Warner SJ, Levin A, Mikelberg FS. Does an association exist between pseudoexfoliation syndrome and chronic kidney disease? Journal of Glaucoma. 2011 Jul 5. PubMed PMID: 21734594.

` `Centre for Health Evaluation and Outcome Sciences 42 Appendix II

Appendix II: Invited Presentations

Anis A. “Comparative effectiveness research and cost-effectiveness analysis. An overview and case study involving the treatment of psoriasis.” Centre for Health Evaluation and Outcome Sciences (CHÉOS), Work in Progress Seminar. Vancouver, BC; Feb 2012.

Anis A. “Drugs, crime and harm reduction: The economics of substance abuse treatment.” CHÉOS, Whistler Winter Workshop on Mental Health and Addiction. Whistler, BC; Feb 18–25, 2012.

Anis A. “Economic evaluation in decision making: Measuring costs and outcomes.” IVC Preceptorship. Amsterdam; Oct 2011.

Anis A. “Sustainability of the healthcare system, and equitable and timely access to new medications—attainable goals?” Canadian Association of Population Therapeutics Conference, Hot Topic Session, Academic Perspective Panelist. Montreal, QC; May 6–8, 2012.

Anis A. “The indirect costs of inflammatory arthritis.” Providence Health Care Research Institute, Move it! The Latest in Mobility Research. Vancouver, BC; Mar 8, 2011.

Anis A. “To biologic or not to biologic: Cost-effectiveness analysis of the RACAT study.” ARC-McCaig Researcher Meeting. Calgary; Oct 2011.

Anis A. “Methods support and development for CIHR’s Strategy on Patient-Oriented Research.” Meeting with Alain Beaudet and members of CIHR SPOR committee and senior staff. UBC Robson Square, Vancouver; Feb 2012.

Ayas NT, Dodek P. “Attributable morbidity and mortality of safety outcomes in ICUs.” CHÉOS, Work in Progress Seminar. St. Paul’s Hospital, Vancouver; Nov 2011.

Ayas N. “Do well-rested doctors make for healthier patients?” Institute for Heart + Lung Health FEST 2011. Vancouver, BC; Mar 2011.

Ayas N. “Health economics of obstructive sleep apnea: Implications for diagnosis and treatment.” World Congress of Sleep Medicine. Quebec City; Sep 2011.

Ayas N. “Obstructive sleep apnea and cardiovascular disease: A tale of two unhappy bedfellows.” Annual Canadian Thoracic Society Meeting. Niagara Falls; Apr 2011.

Ayas N. “Patient safety in the ICU.” Medical Grand Rounds. Vancouver, BC; 2011.

Ayas N. “Restricting resident workhours. The good, the bad, and the ugly.” Visiting Lecturer, Kyoto University Hospital, Hospital-Patient Safety Rounds. Japan; Dec 2011.

Ayas N. “Sleep apnea and cardiovascular disease.” Institute for Heart + Lung Health FEST 2012 Scientific Symposium. Vancouver, BC; Mar 8–9, 2012.

` `Centre for Health Evaluation and Outcome Sciences 43 Appendix II

Ayas N. “Sleep in the critical care unit.” Visiting presenter, Respiratory Sleep Research Rounds, Brigham and Women’s Hospital, Boston; Aug 2011.

Ayas N. “The public health and economic impacts of untreated obstructive sleep apnea, and a discussion of Canadian guidelines for the diagnosis and management of sleep apnea.” 12th Annual National CPAP Meeting. Kyoto University, Japan; Dec 2011.

Bansback N. “Can we use ‘nudges’ to improve clinical decision-making?” CHÉOS, Work in Progress Seminar. Vancouver, BC; Feb 29, 2012.

Bansback N. “Costs offset by biologic drugs in rheumatoid arthritis.” Centre for Health Economics, Economic Evaluation Seminars, University of York. York, North Yorkshire, UK; Jun 6, 2011.

Bansback N. “Costs offset by biologic drugs in rheumatoid arthritis.” School of Health and Related Research, University of Sheffield. Western Bank, Sheffield, South Yorkshire, UK; Jun 2, 2011.

Bansback N. “Costs offset by biologic drugs in rheumatoid arthritis.” Arthritis Research UK Epidemiology Unit, School of Medicine, University of Manchester. Manchester, UK; Jun 2, 2011.

Bansback N. “Incorporating preferences into health care decisions: Giving a voice to patients and the public.” CHSPR Public Seminar, School of Population and Public Health, UBC. Mar 29, 2012.

Beaulieu M. “Managing chronic kidney disease—When to refer? When to reassure?” St. Paul’s Hospital Medicine Grand Rounds: Nephrology. Vancouver, BC; May 26, 2011.

Beaulieu M. “Office management of GFR and declining renal function.” VGH Department of Family Practice and UBC Continuing Professional Development, 47th Annual Post Graduate Review in Family Medicine. Vancouver, BC; Feb 22–24, 2012.

Bottorff JL, Richardson CG. “Tailored, internet delivered messages about smoking and breast cancer: Reactions of girls and boys across BC.” BC Youth Excel Knowledge Exchange Network. BC; Feb 1, 2012. Webinar.

Brown CJ. “Debate: Laparoscopic surgery vs. enhanced recovery pathways.” Evidence-Based Reviews in Surgery, Canadian Surgery Forum. London, ON; Sep 2011. Panel Moderator.

Brown CJ. “Evidence-based reviews in surgery.” Panel, American Society of Colon and Rectal Surgeons Annual Meeting, Vancouver BC; May 2011.

Brown CJ. “Modern management of rectal prolapse.” Society of Obstetricians and Gynaecologists (Canada) Annual Meeting. Vancouver, BC; Jun 2011.

Brown CJ. “Transanal endoscopic microsurgery—Lessons from British Columbia.” Storz TEM Course. Vancouver BC; Dec 2011.

Brown CJ. “Transanal endoscopic microsurgery.” GI Course. Vancouver BC; Oct 2011. Oral presentation.

` `Centre for Health Evaluation and Outcome Sciences 44 Appendix II

Christian WM, Jongbloed K, Louie M, Spittal PM, The Cedar Project Partnership. “The Cedar Project Partnership: OCA governance in action.” Canadian Public Health Association 2011 Conference. Montreal, QC; Jun 19–22, 2011.

Christian WM, Spittal PM, The Cedar Project Partnership. “Legislative genocide, HIV/AIDS research ethics and Aboriginal youth in Canada: Lessons from The Cedar Project Partnership.” Canadian Public Health Association 2011 Conference. Montreal, QC; Jun 19–22, 2011.

Cundiff G. “Diagnosis and management of fecal incontinence.” Post-graduate course: Defecatory Dysfunction, Society of Obstetricians and Gynaecologists of Canada Annual Clinical Meeting. Vancouver, BC; Jun 2011.

Cundiff G. “On the brink: the future of female pelvic medicine and reconstructive surgery in Canada.” Canadian Society of Pelvic Medicine, Society of Obstetricians and Gynaecologists of Canada Annual Clinical Meeting. Vancouver, BC; Jun 2011.

Cundiff G. “Pelvic floor support deficits in defecatory dysfunction.” Post-graduate Course: Defecatory Dysfunction, Society of Obstetricians and Gynaecologists of Canada Annual Clinical Meeting. Vancouver, BC; Jun 2011.

Cundiff G. “Pelvic organ prolapse: Why and how to treat the vaginal apex.” D.A. Boyes Annual Meeting. Vancouver, BC; Oct 27, 2011.

Cundiff G. “Posterior compartment diagnosis and management.” Western Society of Pelvic Medicine Fall Meeting. Oct 22, 2011.

Cundiff G. “Should pelvic reconstructive surgeons use grafts?” Women’s Hospital, Zhejiang University School of Medicine. Hangzhou, China; Feb 9, 2012.

Cundiff G. “The impact of the second stage of labour on pelvic floor disorders.” Post-graduate Course: The second stage of labour: How far should we go?, Society of Obstetricians and Gynaecologists of Canada Annual Clinical Meeting. Vancouver, BC; Jun 2011.

Cundiff G. “Transvaginal mesh: Beneficial for lawyers of patients.” Grand Rounds, Department of Obstetrics & Gynaecology, Providence Health Care. Vancouver, BC; Oct 3, 2011.

Cundiff G. “What is the role of trans-vaginal mesh in prolapse surgery?” Byford Heskett Visiting Professorship, Northwestern University Feinberg School of Medicine. Chicago, IL; Dec 9, 2011.

Dodek P. “Careers in academic science,” and “Scientists in the schools.” IBeyond Year 2 conference (for IB students at Winston Churchill Secondary School). Vancouver, BC; Nov 9, 2011.

Dodek P. “Careers in academic medicine.” Guildford Park Secondary School. Surrey, BC; 2012.

Dodek P. “Evaluation of an internal review process for grants and manuscripts at the Canadian Critical Care Trials Group.” Canadian Critical Care Trials Group, Fall Meeting. Toronto, ON; Nov 16–17, 2011.

Dodek P. “Glycemic control in critical care, and regional ICU database.” BC Patient Safety and Quality Council, Quality Forum: Critical Care Networking Event. Vancouver, BC; Mar 7, 2012.

` `Centre for Health Evaluation and Outcome Sciences 45 Appendix II

Dodek P. “Glycemic control in critical care: Rationale for critically ill patients and measurement for quality improvement.” BC Patient Safety and Quality Council and Clinical Care Management. Vancouver, BC; Nov 30, 2011.

Dodek P. “Improving family satisfaction in the ICU: the role of organizational culture.” CHEST 2011: American College of Physicians Annual International Conference. Honolulu, Hawaii; Oct 25, 2011.

Geller J. “Psychologically-based treatment of eating disorders.” Vancouver Coastal Health, Celebrating Collaborative Partnership in Our Community. Vancouver, BC; Feb 27, 2012.

Gill J, Knoll G, Nickerson P, Cole E, Rose C. “The impact of dialysis exposure on transplant outcomes differs in Canada and the United States.” World Congress of Nephrology. Vancouver, BC; Apr 10, 2011.

Gill J, Ramanathan V. “Complications post-transplant.” World Congress of Nephrology. Vancouver, BC; Apr 10, 2011.

Gill J. “Cardiovascular workup of the potential kidney transplant recipient.” World Congress of Nephrology. Vancouver, BC; Apr 12, 2011.

Gill J. “Diabetes and kidney transplantation.” BC Transplant and The BC Renal Agency Nephrology and Renal Transplant Days 2011. Vancouver, BC; Oct 6–7, 2011.

Gill J. “Expanding living kidney donation: Update on paired exchange.” BC Transplant and The BC Renal Agency Nephrology and Renal Transplant Days 2011. Vancouver, BC; Oct 6–7, 2011.

Gill J. “KDIGO practice guidelines in transplant: How and when should we use them, when should we not?” American Transplant Congress. Philadelphia, PA; May 1, 2011.

Gill J. “Nephrology and kidney transplantation: Better than dialysis.” American Transplant Congress. Philadelphia, PA; May 1, 2011.

Gill J. “Tapering immunosuppression after graft failure.” American Transplant Congress. Philadelphia, PA; Apr 30, 2011.

Grafstein E. “An evening with Charlie Sheen: The acutely psychotic patient.” St. Paul’s Emergency Medicine Update. Whistler, BC; Sep 29–Oct 2, 2011.

Grafstein E. “Electronic solutions for a brighter future in the ED.” Evidence 2 Excellence: BC Emergency Community. Vancouver, BC; Feb 24, 2012. Webinar.

Grafstein E. “Factors affecting regional emergency department selection.” UBC Department of Emergency Medicine 3rd Annual Research Day. Vancouver, BC; Mar 30, 2011.

Harris D. “Emergency department management of acute stroke.” Fraser Health Stroke Symposium. Surrey, BC; May 2011. Oral presentation.

Harris D. “High risk transient ischemic attack.” Canadian Association of Emergency Physicians Annual Meeting, St. John’s, NFLD; Jun 2011.

` `Centre for Health Evaluation and Outcome Sciences 46 Appendix II

Harris D. “The DTU model of TIA care,” “Measurement of secondary prevention strategies,” “Key drivers and change ideas for secondary prevention.” BC Patient Safety and Quality Council, Stroke / TIA Collaborative. Victoria, BC; Nov 2011. Learning Session #2, Opening and Closing Lectures.

Harris D. “Urgency and signs of stroke.” Invited Guest, Stroke Month Presentation at the BC Legislature. Online: http://www.youtube.com/watch?v=nxLhrSRMZfo. Victoria, BC; Jun 2, 2011.

Harris D. “When the left hand doesn’t know what the right hand is doing: stroke mimics.” St. Paul’s Hospital Emergency Medicine Update. Whistler, BC; Sep 2011.

Harris D. “Working together with thrombolysis,” “Emergency department management of acute stroke.” Interior Health Stroke Symposium. Kelowna, BC; Apr 2011.

Harris D. Learning session #1,“Thrombolysis in acute ischemic stroke,” “Key drivers and change ideas,” “Measurement: why and how you do it,” Opening and Closing Lectures. BC Patient Safety and Quality Council, Stroke / TIA Collaborative. Vancouver, BC; Sep 2011.

Humphries K, Thompson C. “Debate: Cardiovascular disease in women: The lack of research is a problem.” Institute for Heart + Lung Health FEST 2012 Scientific Symposium. Vancouver, BC; Mar 8–9, 2012.

Humphries K. “Achieving pan-Canadian consensus on cardiovascular quality indicators and data definitions for patient registries: A recommendation from the Canadian Heart Health Strategy and Action Plan.” Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011.

Humphries K. “What are the ‘Letterman’s’ top lessons from outcomes research in British Columbia?” Engage: Institute for Heart + Lung Health FEST 2011. Vancouver, BC; Mar 8–12, 2011.

Humphries K. “Women and heart disease update.” I <3 Research, UBC Heart Club. Vancouver, BC; Nov 3, 2011.

Humphries K. “Women and heart disease.” Providence Health Care Research Institute. Vancouver, BC; Feb 16, 2012.

Humphries K. “Wonder Woman: Women and cardiovascular disease.” Heart and Stroke Foundation, Luncheon. Vancouver, BC; Mar 5, 2012.

Hunte G. “Creating safety in an emergency department.” Grand Rounds, UBC School of Population and Public Health. Vancouver, BC; Apr 2011.

Hunte G. “Creating safety in an emergency department.” Presented at UBC Centre for Health Care Management seminar. Vancouver, BC; Oct 2011.

Hunte G. “Creating safety in an emergency department.” Resilience Learning Teleconference. Vancouver, BC; Nov 2011.

Hunte G. “Creating safety in an emergency department.” System Safety Society, Canada Chapter. Ottawa, ON; May 2011.

Hunte G. “Making sense of safety.” UBC Department of Emergency Medicine 3rd Annual Research Day. Vancouver, BC; Mar 30, 2011.

` `Centre for Health Evaluation and Outcome Sciences 47 Appendix II

Hunte G. “System safety in complex systems...like ours.” UBC Department of Emergency Medicine Provincial Grand Rounds. Vancouver, BC; Nov 2011.

Khan N. “High blood pressure—why you need to know your numbers.” Institute for Heart + Lung Health, Heart + Lung Health Fest 2012 Public Forum. Vancouver, BC; Mar 6–10, 2012.

Khan N. “What’s new in hypertension?” St. Paul’s Hospital Public Lecture Series. Vancouver, BC; Jan 20, 2011.

Korman L. “Management of chronically suicidal people.” 2011 Canadian Association of Suicide Prevention Pre-Conference: New Conversations on Suicidality. Vancouver, BC; Oct 3, 2011.

Kozak JF. “Physical and mental health of seniors.” United Way’s 2011 Seniors Forum: Aging with Dignity. Vancouver, BC; Nov 16, 2011.

Krausz MK. “Entzug als meilenstein, wendepunkt oder wiederholung.” 20 Jahre qualifizierter Entzugsbehandlung. Munich, Germany; Apr 9 2011.

Krausz MK. “Harm reduction in canada.” ITACA Harm Reduction Seminar. Rome; Jun 2011.

Krausz MK. “International handhabung von benzodiazepin verschreibung,” “International Roundtable for Addiction Medicine.” 12th Interdisciplinary Conference on Addiction Medicine. Munich, Germany; Jul 2011.

Krausz MK. Canadian Psychiatric Association 61st Annual Conference. Vancouver, BC; Oct 13–15, 2011.

Krausz MK. “Trauma and its impact on addiction and mental illness,” “Evidence-based treatment of addiction.” Open Society Institute. Salzburg, Austria; Nov 2011.

Krausz MK. Canadian Society of Addiction Medicine 12th Annual Meeting and Scientific Conference. Vancouver, BC; Nov 4–6, 2011.

Krausz MK. “The SALOME trial—The next step forward towards an optimized substitution therapy.” CHÉOS, Substitution Update. Vancouver, BC; Dec 2, 2011.

Krausz MK. “Clinical research on HEANTOS.” Academy of Science—HEANTOS Symposium. Hanoi, Vietnam; Jan 2012.

Krausz MK, Philips T. “The HEANTOS project and its future options.” CHÉOS, Whistler Winter Workshop on Mental Health and Addiction. Whistler, BC; Feb 18-25, 2012. Oral presentation and organizer.

Krausz MK. “BC Homelessness Survey 2011.” Health of the Homeless: A One Day Youth Homelessness Summit. Vancouver, BC; Jun 14, 2011. Oral presentation and organizer.

Krausz MK. “The early origins of addiction.” CIHR, NIMH, Academy of Finland. Toronto, ON; Apr 2012.

Krausz MK. “E-Mental health.” Foundation and Institute for Addiction Research (ISGF) Workhshop. Zurich, Switzerland; Apr 2012.

` `Centre for Health Evaluation and Outcome Sciences 48 Appendix II

Krausz MK. “E-Go: A comprehensive vision of an online mental health system: The mental health perspective.” CHÉOS, E-Mental Health Conference. Vancouver, BC; Dec 2011. Oral presentation and organizer.

Krausz MK. “Heroin-assisted treatment: SALOME.” CHÉOS, Whistler Winter Workshop on Mental Health and Addiction. Whistler, BC; Feb 18–25, 2012. Oral presentation and organizer.

Levin A, Grant G. “BCPRA and BCT updates.” BC Transplant and The BC Renal Agency Nephrology and Renal Transplant Days 2011. Vancouver, BC; Oct 6–7, 2011.

Levin A. “CanPREDDICT: nontraditional risk factors associated with progressive renal loss.” ASN Renal Week. Philadelphia, PA; Nov 2011.

Levin A. “British Columbia: Use of database for clinical, research and administrative purposes: observational cohort studies of real world practice.” International Symposium of Information Technology, China-Japan Friendship Hospital. Beijing, China; Sep 2011.

Levin A. “Chronic kidney disease: Growing risk in emerging economies and growing opportunities for collaborations.” Meeting of the International Federation of Kidney Foundations. Vancouver, BC; Apr 2011.

Levin A. “Curiouser and curiouser… the story of kidneys, hearts, PTH, phosphate and vitamin D.” Webcast linked to World Kidney Day Symposium. Madrid, Spain; Mar 2011.

Levin A. “Definition and management of CKD.” KDIGO Clinical Practice Conference. Shanghai, China; Feb 2012.

Levin A. “Istanbul and the remaining problem.” CST Annual Scientific Meeting. Quebec City, QC; Feb 23–25, 2012.

Levin A. “Lowering CV risk in patients with chronic kidney disease.” Diabetes Forum/Cardiac Update Meeting. Vancouver, BC; Apr 2011.

Levin A. “Models of care in CKD care: Integrating knowledge & practice.” Webcast presentation for World Kidney Day; Jan 4, 2012.

Levin A. “Perspectives: provincial programs & international initiatives.” Western Canada PD Days. Vancouver, BC; Feb 24, 2012.

Levin A. “The BC Provincial Renal Agency—Care for complex patients: a systems based approach in British Columbia– accountability and transparency.” CERC Webcast. Stanford University, CA; Sep 2011.

Levin A. “Variability of progression, predicting renal decline and survival on and off dialysis.” ASN Renal Week. Philadelphia, PA; Nov 2011.

Levin A. “What is the great opportunity in British Columbia for managing chronic disease?” Heart + Lung Health FEST 2011. Vancouver, BC; Mar 2011.

Lynd L. “Developing a Canadian framework for evaluation and decision-making for expensive drugs for rare diseases through innovation, value, and priority setting.” Canadian Organization for Rare Disorders, 2012 Rare Disease Day Conference. Ottawa, ON; Feb 29–Mar 1, 2012.

` `Centre for Health Evaluation and Outcome Sciences 49 Appendix II

Lynd L. “Economic evaluation and cost effectiveness analysis—The 4th hurdle in drug development.” Centre for Drug Research and Development Seminar. Vancouver, BC; Mar 21, 2011.

Lynd L. “Evaluating patients’ preference for pharmacist provision of chronic disease management using a discrete choice experiment.” Canadian Pharmacists Association National Conference. Montreal, QC; May 28–31, 2011.

Lynd L. “Exploring the international landscape of new methods for benefit-risk assessment.” Canadian Association of Population Therapeutics Annual Conference. Ottawa, ON; Apr 18, 2011.

Lynd L. “The economics of asthma: it’s about more than the dollars.” 1st International Symposium on the Economics of Asthma and Asthma Care, in conjunction with the 8th World Congress on Health Economics. Toronto, ON; Jul 9, 2011. Keynote Speaker.

Mackay M, Butt G, Lauck S, Baumann A. “Igniting nursing research in clinical practice.” Satellite Symposium of the 2011 Marion Woodward Lecture, UBC School of Nursing. Vancouver, BC; Nov 17, 2011.

Mackay M. “Assumptions about ischemic heart disease: Are we really all the same?” Keynote address for Canadian Council of Cardiovascular Nurses’ Annual Meeting and Scientific Sessions. Vancouver, BC; Oct 24, 2011.

Mackay M. “Assumptions about ischemic heart disease: Are we really all the same?” Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011.

Mackay M. “Myocardial ischemia and infarction: Dangerous imbalances.” Cardiac Nursing Day: Putting the Pieces Together, PHC Heart Centre and Institute for Heart + Lung Health. Vancouver, BC; Jun 2, 2011.

Mackay M. “Sex and gender differences in symptoms of myocardial ischemia.” CHÉOS, Work in Progress Seminar. Vancouver, BC; Jan 18, 2012.

Mackay M. “Unstable angina to MI: Better understanding for the non-cardiac nurse.” Vancouver Coastal Health, Nursing Education and Research Rounds. Vancouver, BC; Apr 28, 2011.

Marra C. “Marker-based diagnostics! Are they good value for money?” Engage: Heart + Lung Institute Health FEST 2011. Vancouver, BC; Mar 8–12, 2011.

Marra C. “NSAIDs and cardiovascular risk.” Canadian Pharmacists Association 2012 Conference. Whistler, BC; Jun 1–4, 2012.

Marra CA. “Affordability of marker-based diagnostics: Best practices for personalized medicine (B2PM).” Sheraton Vancouver Wall Centre Hotel. Vancouver BC; Mar 9, 2011.

Marra CA. “Anti-TNF therapies: Is there a difference in real life?” Highlights of the CADTH Therapeutic Review, IMID. Athens, Greece; Mar 10–12, 2011.

Marra CA. “Community pharmacists in focused surveillance for drug safety and effectiveness: A case study of anti- hypertensives in pregnancy.” CIHR Knowledge Translation Workshop, Ottawa, ON; Mar 28, 2011.

Marra CA. “Health economics: Application to scleroderma.” McGill University, Montreal, QC; Jul 2011.

` `Centre for Health Evaluation and Outcome Sciences 50 Appendix II

Marra CA. “How can pharmacists participate in multidisciplinary care in arthritis?” Abbott Pharmacy Forum. Toronto, ON; Oct 2011.

Marra CA. “Personalized medicine: value for money?” BC Clinical Genomics Network Annual Conference. Pan Pacific Hotel, Vancouver, BC; Apr 27, 2011.

Marra CA. “Pharmacists’ roles in rheumatology.” Rheumatology Grand Rounds, University of Manitoba. Winnipeg, MB; Oct 2011.

Marra CA. “Pharmacy-based immunization in rural communities strategy (PhICS): Interim results.” Canadian Pharmacists Association National Conference. Montreal, QC; May 28–31, 2011.

Marra CA. “The economics of personalized medicine.” Personalized Medicine Initiative. Vancouver, BC; Oct 2011.

Marra CA. “What is value for money in health care?” RCI Panel, Bristol Myers Squibb. Chicago, IL; Oct 2011.

Memetovic J, Richardson CG. “Examining the relationship between psychological functioning and adolescents’ intention to use tobacco, alcohol, and marijuana.” CHÉOS, Lost in Translation: Seeking answers in addiction and concurrent disorders. Vancouver, BC; Feb 15–17, 2011.

Oviedo-Joekes E. “Heroin-assisted treatment and the Canadian studies.” International Drug Policy Reform Conference. Los Angeles, CA; Nov 4–5, 2011.

Palepu A, Hwang S. “An update on the Housing and Health in Transition Study.” CHÉOS, Work in Progress seminar series. Vancouver, BC; Apr 6, 2011.

Palepu A. “Addressing harassment spoken and unspoken.” Annual ACP Meeting. San Diego, CA; Apr 8, 2011.

Palepu A. “Breaking down silos: Reinforcing the links between the housing, health and homelessness sectors.” Canadian Housing Renewal Association Pre-Congress. Regina, SK; Jun 20, 2011.

Palepu A. “Careers in internal medicine—Clinician scientist and CIP.” UBC Internal Medicine core academic half day. Vancouver, BC; Jun 1, 2011.

Palepu A. “How to get your work published.” UBC Department of Family Practice Research Skills Workshop 2012. Vancouver, BC; Mar 4, 2012.

Palepu A. “Knowledge exchange on health and homelessness in Canada on the HHiT study.” Vancouver, BC; Nov 9, 2011.

Palepu A. “Methodological issues in recruiting and following vulnerable populations.” Department of Community Health Sciences/Calgary Institute for Population and Public Health seminar series. Calgary, AB; Dec 9, 2011.

Palepu A. “Open Medicine: An editor’s view of open access, social technologies & biomedical publishing.” UBC School of Population and Public Health Course 581H: Social media in health & medicine. Vancouver, BC; Sep 29, 2011.

Palepu A. “Update on the GIM Fellowship Program to the Community and Rural Internal Medicine (CRIM) section of the BCMA.” Apr 22, 2011.

` `Centre for Health Evaluation and Outcome Sciences 51 Appendix II

Palepu A. Medicine at the fringes: “Homelessness and poverty.” Canadian Society of Internal Medicine Annual Scientific Meeting. Halifax, NS; Oct 12, 2011. Plenary panel.

Phang PT. “Colorectal cancer care.” PHC Department of Surgery Grand Rounds. Vancouver, BC; Apr 2011.

Phang PT. “Expediting return of bowel function following colorectal surgery.” North Pacific Surgical Association. Vancouver, BC; Nov 2011.

Phang PT. “Rectovaginal and rectourethral fistulas.” Optimum Management, Canadian Society of Colon and Rectal Surgeons. London, ON; Sep 2011.

Phang PT. “TME education in North America.” American Society of Colon and Rectal Surgeons, Annual Meeting 2011. Vancouver, BC; May 14–18, 2011.

Raval M, Brown CJ. “TEM hands-on course.” UBC 4th Annual Dr. Nis Schmidt General Surgery Update. Vancouver, BC; Dec 1–3, 2011. Course presentation.

Raval M. “Pelvic pouch for inflammatory bowel disease.” BC Children’s Hospital Surgical Grand Rounds. Vancouver, BC; Jun 2011.

Richardson CG. Health of the Homeless: A one day youth homelessness summit. Member of expert panel discussion. Vancouver, BC; Jun 14, 2011.

Sawatzky R. “Breakfast roundtable: M-Plus.” The 2011 International Society for Quality of Life Research Meeting. Denver, CO; Oct 26–29, 2011.

Sawatzky R. “Diversity and the measurement of quality of life.” CHÉOS, Work in Progress Seminar Series. Vancouver, BC; Sep 8, 2011.

Schechter M. “Why clinical trials?” Launch of the Makerere University Clinical Trials Unit. Kampala, Uganda; Apr 1, 2011. Plenary Speaker.

Schütz CG. “Stress, impulse control and substance use.” CHÉOS, Whistler Winter Workshop on Mental Health and Addiction. Whistler, BC; Feb 18–25, 2012.

Shojania K. “Cognitive errors in medicine.” Grand Rounds. Calgary, Alberta; Mar 30, 2011.

Simpson P, Taipale P. “Delirium management: Nursing strategies to improve prediction, identification and prevention.” St. Paul’s Hospital, NEARR Nursing Education and Research Rounds. Vancouver, BC; Jul 28, 2011. Oral Presentation and webinar: http://www.imspirenet.ca/wiki/archive-nearrsessions.

Simpson P. “Creating an evidence-based pathway for delirium.” CHÉOS, Work in Progress Seminar. Vancouver, BC; Mar 14, 2012.

Simpson P. “Delirium: promoting innovations in practice and policy.” Forum for Advanced Practice Nursing: Practice and Policy Innovators, Clinical Nurse Specialist Association of BC (CNSABC). Vancouver, BC; Apr 2011.

Simpson P. “Family nursing.” St. Paul’s Hospital, Mental Health Education Days. Vancouver, BC; Mar 14 and 23, 2011.

` `Centre for Health Evaluation and Outcome Sciences 52 Appendix II

Simpson P. “Pathway to delirium: Prediction, prevention, identification and intervention.” 2nd Annual CAPM Conference. Vancouver, BC; Oct 12, 2011. Panel presentation.

Simpson P. “The Family Systems Nursing – Relational Practice Model: A family-centered approach to mental health.” Ministry of Health BC, Mental Health and Substance Use (MHSU) Sector Survey Consultation Group. Victoria, BC; Feb 1, 2012.

Spittal PM, Christian WM. “The Cedar Project and harm reduction.” No Harm in Trying: Atlantic Harm Reduction Gathering. Dartmouth, NS; Mar 25–27, 2012.

Spittal PM, Thomas V. “The Cedar Project: Implications for men and women.” One Body, One Mind, One Spirit: Pathways to Wellness conference. Prince George, BC; Feb 14–16, 2011.

Stenstrom R. “From scorching to room temperature in no time at all: Sepsis update.” St. Paul’s Emergency Medicine Update. Whistler, BC; Sep 29–Oct 2, 2011.

Strehlau V for Somers J. “Homelessness in Vancouver.’ CHÉOS, Whistler Winter Workshop on Mental Health and Addiction. Whistler, BC; Feb 18–25, 2012.

Strehlau V, Torchalla I, Linden I. “Concurrent PTSD and substance use.” CHÉOS, Whistler Winter Workshop on Mental Health and Addiction. Whistler, BC; Feb 18–25, 2012.

Suzuki M, Sawatzky R, Roberts D. “Partnering: An essential strategy for a provincial nurse survey.” Sigma Theta Tau International Honor Society of Nursing: 17th Annual Ethel Johns Research Day. Vancouver, BC; Feb 4, 2012.

Torchalla I. “Concurrent trauma and addiction–gender issues and promising treatment approaches.” Winter Workshop on Addiction Research, UBC Institute of Mental Health. Whistler, BC; Feb 18–25, 2012.

Torchalla I. “The science of stopping smoking.” Institute for Heart + Lung Health FEST 2012 Scientific Symposium. Vancouver, BC; Mar 8, 2012.

Trerise B. “Innovation: building the culture and realizing the benefits.” National Healthcare Leadership Conference. Whistler, BC; Jun 6, 2011.

Westerberg B. “Ear’itating questions: Troubleshooting in the office,” and other presentations. Sea Conferences, Surgery and Infectious Diseases + Practice Management Conference. Caribbean; Dec 2–11, 2011.

Westerberg B. “Approach to the chronically draining ear: How I approach cholesteatoma.” Japan Lab 2011, Swedish Neurosciences Institute. Seattle, WA; Aug 22–25, 2011.

Westerberg B. “Practical update on cochlear implants.” Aural rehabilitation of hearing loss panel, 15th Annual McGill University Update in Otolaryngology. Montreal, QC; May 18–20, 2011.

Westerberg B. “Special humanitarian outreach presentation: Uganda.” 65th Annual Meeting Canadian Society of Otolaryngology – Head and Neck Surgery. Victoria, BC; May 22–24, 2011.

Wong H. “Statistics education for health researchers: A (personal) modern view.” UBC School of Population and Public Health. Vancouver, BC; Sep 2011.

` `Centre for Health Evaluation and Outcome Sciences 53 Appendix III

Appendix III: Abstracts

Alimenti A, Sauvé L, Forbes J, Singer J, Lee T, Money D, Samson L, Bitnun A, Lapointe N, and the Canadian Pediatric Perinatal AIDS Research Group (CPARG). Prenatally HIV-infected children in canada and those born in Canada and those born elsewhere. Canadian Association for HIV Research Annual Meeting. Toronto, ON; Apr 14–17, 2011.

Almeida F, Marra C, Lowe A, Fleetham J, Lynd L, Ayas N. Patient preferences and experiences of CPAP and oral appliances for the treatment of sleep apnea: A qualitative analysis. AJRCCM 183; 2011:A6330.

Aslani N, Phang PT, Raval MJ, Brown CJ. Influence of surgeon and hospital factors on implementation of laparoscopic colon cancer surgery in British Columbia. Canadian Surgery Forum. London, ON: Sep 15–18, 2011.

Avina-Zubieta A, Sayre EC, Bernatsky S, Shojania K, et al. Adult prevalence of systemic autoimmune rheumatic diseases (SARDS) in British Columbia, Canada. ACR/ARHP Scientific Meeting. Chicago, IL; Nov 4–9, 2011. Oral presentation, #1846.

Baldwin C, Farah M, Leung M, Levin A, Taylor P, Kiaii M. Multimodal approach to treatment of calciphylaxis improves outcomes: a case series. World Congress of Nephrology 2011. Vancouver, BC; Apr 8–12, 2011.

Bance M, Westerberg B, David E, Liu R, Schramm D. Pitfalls in stapedotomy surgery. 65th Annual Meeting Canadian Society of Otolaryngology—Head and Neck Surgery. Victoria, BC; May 22–24, 2011.

Bansback N, Bryan S, Li L, Lynd LD. Value clarification in decision aids: A missing element? 33rd Annual Meeting of the Society for Medical Decision Making. Chicago, IL; Oct 22–26, 2011.

Bansback N, Chiu J, Anis AH. Are trials of interventions for rheumatoid arthritis collecting and reporting sufficient data for policymakers? The 12th Annual European Congress of Rheumatism (EULAR 2011). London, UK; May 25–28, 2011.

Barbour S, Er L, Magil A, Reich H, Levin A. Ethnic differences in renal and patient survival in IgA nephropathy. World Congress of Nephrology 2011. Vancouver, BC; Apr 8–12, 2011.

Barbour S, Greenwald A, Djurdjev O, Levin A, Hladunewich M, Cattran D, Reich H. Disease-specific risk of venous thromboembolic events in idiopathic glomerulonephritis. World Congress of Nephrology 2011. Vancouver, BC; Apr 8–12, 2011.

Bashir J, Yamashita M, Karim SS, Tung S, Yeung-Lai-Wah J, Chakrabarti S, Hahn E, Sanatani S, Kerr C, Cowan S, Humphries K. Behaviour of a population of patients with the Sprint Fidelis Lead. American Heart Association Scientific Sessions. Orlando, FL; Nov 12–16, 2011 2011; 124:A14686.

Bedouch P, Sadatsafavi M, FitzGerald JM, Marra CA, Lynd LD. Health care costs of uncontrolled asthma: a population-based cohort study in British Columbia, 2002–2007. Canadian Association for Population Therapeutics, Knowledge to Provide Evidence for Health Care Decision-Makers: Clinical Practice and Research Methodology. Ottawa, ON; Apr 17–19, 2011. Oral presentation, #10.

` `Centre for Health Evaluation and Outcome Sciences 54 Appendix III

Bedouch P, Sadatsafavi M, FitzGerald JM, Marra C, Lynd LD. Initiation of controller medication in newly diagnosed asthma patients: impact on economic resource utilization. European Respiratory Society Annual Congress. Amsterdam, Netherlands; Sep 24–28, 2011.

Bedouch P, Sadatsafavi M, FitzGerald JM, Marra CA, Lynd LD. Trends in asthma-related direct medical costs in British Columbia, Canada. 8th World iHEA Congress in Health Economics/International AllerGen Symposium on Asthma and Economics. Toronto, ON; Jul 10–13, 2011.

Bottorff JL, Bissell LJ, Richardson CG, Haines-Saan R, Oliffe JL, Hutchinson P, Gotay C, Johnson K. Breast cancer and smoking: Designing messages for youth. Canadian Association of Psychosocial Oncology Conference. Toronto, ON; May 4–6, 2011.

Bottorff JL, Richardson CG, Haines-Saah R, Oliffe J, Hutchinson P, Okoli C, Ratner P, Gotay C, Johnson K. Smoking and breast cancer: Girls’ and boys’ reactions to tailored, internet delivered messages. 7th National Canadian Tobacco or Health Conference. Toronto, ON; Nov 1–3, 2011.

Bowker SL, Richardson K, Marra CA, Johnson JA. Time-varying risk of breast cancer after onset of type II diabetes: Evidence of detection bias in post-menopausal women. 47th Annual Meeting of the European Association for the Study of Diabetes. Lisbon, Portugal; Sep 12–16, 2011.

Boyd JH, Ayas N, Wacharasint P, Parthasarathy S. Sleep deprivation worsens lipopolysaccharide (LPS) induced cardiac dysfunction in mice. American Thoracic Society 2011 International Conference. Denver, CO; May 13–18, 2011. AJRCCM 183; 2011:A6405.

Browne S, Gill J, Dong J, Rose C, Gill JS. Should low GFR preclude consideration for pancreas after kidney transplantation? American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Bruce KR, Steiger H, Geller J, Sycz L, Assouline I, Israel M. Relationships among readiness for change, readiness internality, autonomous motivation for therapy and eating disorder treatment outcomes. Eating Disorders Research Society 17th Annual Meeting. Edinburgh, Scotland; Sep 22–24, 2011.

Brunner NW, Wang H, K Ramanathan, Khan NA. Mortality amongst Chinese, South Asian and White patients with diabetes prescribed statin therapy. European Society of Cardiology EuroPrevent International Conference 2011. Geneva, Switzerland; Apr 14–16, 2011. Poster presentation.

Brunner NW, Wang H, K Ramanathan, Khan NA. Mortality amongst Chinese, South Asian and White patients with diabetes prescribed statin therapy. The Heart.Org. Apr 15, 2011.

Brunner NW, Wang H, Ramanathan K, Khan NA. Mortality Amongst South Asian, Chinese and White patients with diabetes prescribed statin therapy. Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011. Poster presentation, 314–104.

Brydges R, Peets A, Issenberg SB, Lam G, Regehr G. Scaffolding medical students’ self-regulated learning on a cardiopulmonary patient simulator: Less can be more. AMEE. Vienna, Austria; Aug 27–31, 2011. Poster presentation, 3BB2.

` `Centre for Health Evaluation and Outcome Sciences 55 Appendix III

Chang P, Gill J, Dong J, Rose C, Browne S, Gill JS. Use of obese living kidney donors. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Chang P, Gill J, Rose C, Dong J, Browne S, Gill JS. The importance of PRA in HLA identical kidney transplant recipients. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Chavoshi N, Joseph K, Schechter MT, Spittal PM. The Cedar Project: Pap smear testing among young Aboriginal women who use injection and non-injection drugs in two Canadian cities. For the Cedar Project Partnership. 20th Annual Canadian Conference on HIV/AIDS Research. Toronto, ON; Apr 14–17, 2011.

Chavoshi N, Joseph K, Schechter MT, Spittal PM, for the Cedar Project Partnership. The Cedar Project: Access to sexual healthcare among young Aboriginal women vulnerable to the harms of illicit drug use in British Columbia. 3rd North American Congress of Epidemiology. Montréal, QC; Jun 21–24, 2011.

Chen V, Wideman R, Tebbutt S, Ng R, McManus B, Wilson-McManus J, Beaulieu M, Djurdjev O, Levin A. Biomarkers of disease progression in chronic kidney disease patients. World Congress of Nephrology 2011. Vancouver, BC; Apr 8–12, 2011.

Christian WM, Thomas V, Jongbloed K, Louie M, Spittal P, Cedar Project Partnership. The Cedar Project Partnership: OCAP governance in action. 3rd North American Congress of Epidemiology. Montréal, QC; Jun 21–24, 2011.

Cole EH, Prasad R, Gill JS. Thymoglobulin induction-reduced cyclosporine exposure, and early corticosteroid reduction to reduce new-onset diabetes and acute rejection in kidney transplant recipients. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Cooper C, Thorne A, Singer J , Harris M, Cohen J, Smieja M, Rachliws A, Kilby D, Canadian HIV Trials Network Influenza Vaccine Research Group. Statin use does not increase immunogenicity of seasonal influenza vaccine in HIV infected adults. Canadian Association for HIV Research Annual Meeting. Toronto, ON; Apr 14–17, 2011.

Cooper C, Thorne A, Singer J, Conway B, Kilby D, Klein M, Shafran S, Haase D, Walmsley S, Canadian HIV Trials Network Influenza Vaccine Research Group. Vitamin D supplementation does not influence immunogenicity of seasonal influenza vaccine in HIV infected adults. Canadian Association for HIV Research Annual Meeting. Toronto, ON; Apr 14–17, 2011.

Côté HCF, Soudeyns H, Lapointe N, Alimenti A, Lamarre V, Sattha B, Maan E, Gadawski I, Thorne A, Singer J, Money D, Forbes JC and the CIHR Emerging Team in HIV therapy and aging (CARMA). Leukocyte telomere length in HIV-infected and HIV-Exposed uninfected children; shorter telo mere length with uncontrolled HIV viremia. 2nd International Workshop on HIV and Aging. Baltimore, MD; Oct 27–28, 2011.

Côté HCF, Zanet D, Sattha B, Maan E, Gadawski I, Burdge D, Thorne A, Forbes JC, Singer J, Money D, Pick N and the CIHR Emerging Team in HIV therapy and aging (CARMA). HIV infection is marginally associated with shorter leukocyte telomere length. 19th Conference on Retroviruses and Opportunistic Infections. Seattle, WA; Mar 5–8, 2012.

` `Centre for Health Evaluation and Outcome Sciences 56 Appendix III

Crema MD, Sayre EC, Roemer FW, Wong H, Thorne A, Singer J, Esdaile JM, Kopec JA, Nicolaou S, Guermazi A, Cibere J. The association of MRI-detected subchondral bone marrow sclerosis with cartilage loss in a cohort of subjects with knee pain. Osteoarthritis Research Society International (OARSI) 2012 World Congress on Osteoarthritis. Barcelona, Spain: Apr 26–29, 2012.

Cundiff GW. Predictors of outcome in critically ill pregnant and postpartum women. Society of Obstetricians and Gynecologists of Canada Annual Clinical Meeting. Vancouver, BC; Jun 8, 2011.

Dias Lima V, Sierra-Madero J, Wu Z, Singer J, Milan D, Montaner JSG. Cumulative plasma HIV-1 level as a novel tool to evaluate antiretroviral therapy efficacy at the individual and public health levels. International AIDS Society Annual Meeting. Rome, Italy; Jul 17–20, 2011.

Doan Q, Sheps, S, Wong H, Singer J, Johnson D, Kissoon N. Families’ willingness to receive care by physician assistants in a pediatric emergency department. CCHCSP 9th Annual Symposium. Ottawa, ON; Oct 14–16, 2011.

Dunn EC, Brown KE, Zelichowska J, Srikameswaran S, Geller J. The effectiveness of a readiness-based model of service delivery for individuals with eating disorders. Association for Behavioural and Cognitive Therapies Convention. Toronto, ON; Nov 10–13, 2011.

Dunn EC, Brown KE, Zelichowska J, Srikameswaran S, Geller J. The effectiveness of a readiness-based model of service delivery for individuals with eating disorders. Eating Disorders Research Society 17th Annual Meeting. Edinburgh, Scotland; Sep 22–24, 2011.

Fairhead T, Hendren E, Sherlock C, Shi L, Crowcroft N, Kumar D, Landsberg D, Knoll G, Gill JS. Poor seroprotection after H1N1 vaccination in kidney transplant recipients. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Finckh Z, Escher M, Liang MH, Bansback N. Factors involved in the decision to take medications to prevent rheumatoid arthritis in first degree relatives of patients with RA. A Discrete Choice Experiment. 2011 American College of Rheumatology ACR/AHRP Annual Scientific Meeting. Chicago, IL; Nov 5–9, 2011.

Fox N, Wong G, Ayas N, Stradling JR, Fleetham J. The impact of six months of CPAP on brain natriuretic peptide in non- sleepy patients with OSA. AJRCCM 183; 2011:A6074.

Frood S, Matteson C, Zelichowska J, Jones MI, Srikameswaran S, Chanoine JP, Geller J, Finegood DT. Understanding complexity of health behaviour change in overweight youth. The Canadian Obesity Network-Réseau canadien en obésité (CON-RCO) 2nd National Obesity Summit Conference. Montréal, QC; Apr 28–May 1, 2011.

Geller J. Overcoming barriers in the eating disorders: Self-compassion, engagement and readiness for change. Academy for Eating Disorders 2011 International Conference. Miami, FL; Apr 28–30, 2011.

Gill J, Dong J, Rose C, Browne S, Landsberg D, Gill JS. Living kidney donation rates in high income African Americans are double those of White Americans. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Gill J, Gill JS, Johnston O, Landsberg DN. An exercise in age-matching—balancing equity and utility in organ allocation. Canadian Society of Transplantation Annual; Scientific Conference. Quebec City, QC; Mar 14–16, 2012.

` `Centre for Health Evaluation and Outcome Sciences 57 Appendix III

Gill J, Rose C, Dong J, Browne S, Chang P, Landsberg D, Gill J. The increase in deceased donation rates in the US does not explain the retraction of living donation. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Gill J, Rose C, Dong J, Browne S, Chang P, Landsberg D, Gill JS. Allocation and outcomes of DCD-ECD Kidneys in the U.S. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Gill J, Rose C, Dong J, Browne S, Landsber D, Gill JS. A comparison of induction agents with steroid free immunosuppression in kidney transplant recipients in the U.S. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Gill JS, Browne S, Dong J, Johnston O, Chang P, Rose C, Landsberg D, Gill J. Pancreas after kidney transplantation is associated with long-term improvement in kidney allograft survival. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Gill JS, Gill J, Dong J, Browne S, Chang P, Knoll G. Which surrogate: Acute rejection or GFR? American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Grunau GL, Taylor CM, Humphries KH, Ahmadi A, Rezazadeh S, Faraji R, Amid S, O’Connell T, Heilbron B, Leipsic J. Battle of the sexes—Is there a difference in outcome following CCTA? Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011. Poster presentation, 576–046.

Gunn G, Ewing G, Sawatzky R. “The relative importance of support domains in explaining adverse effects from family care giving.” The 9th Palliative Care Congress. Newcastle Gateshead, UK; Mar 14–16, 2012. Oral presentation.

Halwani Y, Chan S, Jones S, Phang PT, Nabi IR, Wiseman SM. Autocrine motility factor receptor expression by colon and rectal cancer: prognostic significance. The American Society of Colon and Rectal Surgeons Annual Meeting. Vancouver, BC; May 14–18, 2011.

Hamadani L, Richardson CG, Gotay C. Using Google AdWords to quantify Canadians’ internet searches for cancer prevention information. Canadian Public Health Association 2011 Annual Conference. Montréal, QC; Jun 19–22, 2011.

Hohl CM, Yu ES, Hunte G, Brubacher JR, Hosseini F, Argent C, Chan W, Wiens M, Sheps S, Singer J. Clinical decision rules to improve the detection of adverse drug events in emergency department patients. 2011 Scientific Assembly of the American College of Emergency Physicians. San Francisco, CA; Oct 8–11, 2011.

Hunte GS. Creating safety in an emergency department in clinical collaborations: Applied clinical medical anthropology, Part I (McKellin B, Chair). Expanding the influence of applied social science. 71st Annual Meeting of the Society for Applied Anthropology. Seattle, WA; Mar 29–Apr 2, 2011.

Izadnegahdar M, Sedlak T, Lee M, Gao M, Bairey Merz C, Humphries K. Sex differences in risk factor profile and outcomes of young adults with obstructive coronary artery disease. American College of Cardiology’s (ACC’s) 61st Annual Scientific Session & Expo. Chicago, IL; Mar 9–11, 2012.

Izadnegahdar M, Singer J, Gao M, Thompson CR, Kopek J, Humphries KH, AMI55 Investigators. Are young women’s acute myocardial infarction (AMI) symptoms really different from men’s? Preliminary Results from AMI55 Study. Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011. Poster presentation, 246–025.

` `Centre for Health Evaluation and Outcome Sciences 58 Appendix III

Izadnegahdar M, Singer J, Gao M, Thompson CR, Kopec J, Humphries KH, AMI55 Investigators. Sex differences in one month health status of young adults post-acute myocardial infarction: Preliminary Results from AMI55 Study. Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011. Poster presentation, 247–023.

Jackevicius C, Rahme E, Essebag V, Eisenberg M, Humphries K, Tu J, Behlouli H, Pilote L. Sex differences related to medication prescription and clinical outcomes in patients with atrial fibrillation. Canadian Cardiovascular Congress 2011. Vancouver, BC; Oct 22–26, 2011.

Jongbloed K, Thomas V, Christian W, Schechter MT, Spittal PM. The Cedar Project: Gender differences in HIV vulnerability associated with unstable housing among young Aboriginal people who use drugs in Vancouver and Prince George, BC. North American Housing and HIV/AIDS Research Summit, New Orleans, USA; Sep 21–23, 2011.

Jongbloed K, Bingham B, Schechter MT, Spittal PM, Cedar Project Partnership. The Cedar Project: Unstable housing and HIV vulnerability among young Aboriginal men and women who use drugs in Vancouver and Prince George. 3rd North American Congress of Epidemiology. Montréal, QC; Jun 21–24, 2011.

Jongbloed K, Christian WM, Schechter MT, Spittal PM, Cedar Project Partnership. The Cedar Project: Predicting safe injection site use among young Aboriginal people who use injection drugs in Vancouver. 3rd North American Congress of Epidemiology. Montréal, QC; Jun 21–24, 2011.

Jongbloed K, Thomas V, Christian WM, Schechter MT, Spittal PM, Cedar Project Partnership. The Cedar Project: Differences in HIV vulnerabilities associated with unstable housing over time among young Aboriginal men and women who use drugs in Vancouver and Prince George, BC. 20th Annual Canadian Conference on HIV/AIDS Research. Toronto, ON; Apr 14–17, 2011. Poster presentation, P149.

Khan N, et al. Cardiovascular disease and diabetes in umlticulturally diverse communities: Lessons for CVD prevention, treatment and management. Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011. Oral presentation.

Kiaii M, Farah M, Jung B, Beaulieu M, Djurdjev O, Levin A. Significant thrombocytopenia associated with electron-beam sterilized hemodialysis membranes. World Congress of Nephrology 2011. Vancouver, BC; Apr 8–12, 2011.

Kozak J, Mithani A, Alzona A. Who is screening what? Canadian Geriatrics Society 31st Annual Scientific Meeting. Vancouver, BC; Apr 14–16, 2011.

Krausz MK, Karow A. “Quality of life as health indicator among individuals with addiction and complex concurrent disorders.” 15th World Congress of Psychiatry: World Psychiatry 2011: Our Heritage and Our Future. Buenos Aires, Argentina; Sep 18–22, 2011. Oral Presentation, RS14.3.

Lea J, Brown E, Chau J, Westerberg B. Radiographic imaging of the cochlear implant candidate: A Pre-operative Model to Predict Ease of Access to the Round Window. 28th Politzer Society Meeting. Athens, Greece; Sep 28–Oct 1, 2011.

Lea J, Westerberg B, Mondin R, Huins C. Otologic surgery in Uganda: Needs assessment. 65th Annual Meeting Canadian Society of Otolaryngology—Head and Neck Surgery. Victoria, BC; May 22–24, 2011.

Leung VWY, Soon JA, Lynd LD, Marra CA, Levine M. A population-based comparison of the effectiveness of two emergency contraceptives. The 6th Asian Conference on Pharmacoepidemiology. Beijing, China; Oct 30, 2011.

` `Centre for Health Evaluation and Outcome Sciences 59 Appendix III

Leung VWY, Soon JA, Lynd LD, Marra CA, Levine M. The levonorgestrel and Yuzpe regimens of emergency contraceptives: a comparative effectiveness study. EC Jamboree 2011: Annual Meeting of the International Consortium for Emergency Contraception and the American Society for Emergency Contraception. New York City, NY; Oct 3, 2011.

Leung VWY, Soon JA, Lynd LD, Marra CA, Levine M. Comparison of pregnancy rates after two hormonal emergency contraceptives. North American Forum on Family Planning Annual Meeting. Washington, DC; Oct 22–24, 2011.

Leung VWY, Soon JA, Marra CA, Lynd LD, Levine M. Adjudication of pregnancy-related health outcomes using administrative data. The 6th Asian Conference on Pharmacoepidemiology. Beijing, China; Oct 29, 2011.

Leung VWY, Soon JA, Marra CA, Lynd LD, Levine M. History of regular hormonal contraceptive use among emergency contraceptive users in British Columbia. Canadian Association for Population Therapeutics, Knowledge to Provide Evidence for Health Care Decision-Makers: Clinical Practice and Research Methodology. Ottawa, ON; Apr 17–19, 2011. Poster presentation, #48.

Levin A. CanPREDDICT: Canadian study for the prediction of dialysis, death and cardiovascular risk in CKD patients: results of one year follow up. World Congress of Nephrology 2011. Vancouver, BC; Apr 8–12, 2011.

Lin RJ, Chau J, Krall R, Westerberg B. Systematic review of risk factors of adult sudden sensorineural hearing loss. 65th Annual Meeting Canadian Society of Otolaryngology—Head and Neck Surgery. Victoria, BC; May 22–24, 2011.

Lix LM, Huang Y, Sajobi TT, Sawatzky R, Liu J, Mayo N. Detecting different forms of response shift with structural equation modeling: An application to inflammatory bowel disease. The 2011 International Society for Quality of Life Research meeting. Denver, CO; Oct 26–29, 2011. Available online at: http://www.isoqol.org/2011conference/ac11abstractbook.pdf. Oral presentation, #214.

Mackay M et al. Concurrent session: nursing education. Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011. Oral presentation, N045.

Margolick J, Appuzo L, Tossonian H, Singer J, Fraser C, Loutfy M, Rachlis A, El-Helou P, Kasper K, Conway B. Effect of randomized HAART on viral suppression of therapy in patients with acute/early HIV Infection. 19th Conference on Retroviruses and Opportunistic Infections. Seattle, WA; Mar 5–8, 2012.

McCormick N, Marra C, Colley L, Grubisic M, Lacaille D, Avina-Zubieta JA. Direct medical costs in patients with systemic autoimmune rheumatic diseases. 2011 Canadian Network for Improved Outcomes in Systemic Lupus Erythematosus (CaNIOS) Annual Meeting. Quebec City, QC; Oct 29–30, 2011.

McCormick N, Marra C, Colley L, Grubisic M, Sayre EC, Avina-Zubieta JA. Direct medical costs in patients with systemic autoimmune rheumatic diseases. Canadian Rheumatology Association- Arthritis Health Professions Association (CRA-AHPA) Annual Scientific Meeting. Victoria, BC; Mar 28–31, 2012.

McKinley K, Currie L, Lear S, Mackay M. Measuring dietary pattern change after cardiac events. Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011. Poster presentation, NP005.

Mehrotra A, Rose C, Gill J, Gill JS. Acute kidney injury is most frequent, but has the lowest impact on graft loss in CKD stage 4/5 kidney transplant recipients. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

` `Centre for Health Evaluation and Outcome Sciences 60 Appendix III

Mick P, Westerberg B, Kakande E, Benton A, Byaruhanga R. Access barriers hinders the effective treatment of chronic suppurative otitis media in Uganda. 65th Annual Meeting Canadian Society of Otolaryngology—Head and Neck Surgery. Victoria, BC; May 22–24, 2011.

Mithani A, Kozak J, Alzona E. Evaluation of a standardized protocol for medication review in long term care facilities. Canadian Geriatrics Society 31st Annual Scientific Meeting. Vancouver, BC; Apr 14–16, 2011.

Moore A, DiGiovanni B, Pinney SJ. Current non-operative and surgical management of recalcitrant plantar fasciitis among academic foot and ankle surgeons. AOFAS Annual Meeting. Washington DC; Jul 8, 2011. Poster presentation.

Mori T, Atashband S, Lea J, Westerberg B. Cochlear implantation in patients with canal-wall-down mastoid cavities: evidence-based recommendations. 28th Politzer Society Meeting. Athens, Greece; Sep 28–Oct 1, 2011.

Muscedere J, Sinuff T, Cook DJ, Dodek P, et al. Active observational study of the adoption and transfer of clinical practice guidelines through education, for ventilator associated pneumonia: The Abate Vap study. American Thoracic Society International Conference. Denver, CO; May 13–18, 2011. Am J Respir Crit Care Med 183;2011:A3736. Poster Discussion.

Naidoo S, Zelichowska J, Geller J. A Canadian perspective on cross-cultural differences in eating disorders. The 2011 Annual Meeting of the Society for the Study of Psychiatry and Culture. Seattle, WA; Jun 2–4, 2011.

Norena M, Wong H, Ayas N, Dodek PM. ICU length of stay and mortality attributed to ICU-acquired clostridium difficile- associated diarrhea. American Thoracic Society International Conference. Denver, CO; May 13–18, 2011. Am J Respir Crit Care Med 183; 2011:A2372. Poster Discussion.

Norena M, Wong H, Ayas N, Dodek PM. ICU length of stay and mortality attributed to ICU-acquired clostridium difficile associated diarrhea. AJRCCM 183; 2011:A2372.

Ouellet E, Lee T, Baril JG, Trottier B, Harris M, Kovacs K, Angel J, Rachlis A, Smaill F, Walmsley S, Matte S, Loutfy M, Logue K, Conway B, Gill J, Routy JP, Singer J, Bernard N, Tremblay C. Comparison of the slope of CD4 decline in HIV+ slow progressors according to virological control (CTN 247). Canadian Association for HIV Research Annual Meeting. Toronto, ON; Apr 14–17, 2011.

Ouzounian M, Ghali W, Yip AM, Buth KJ, Humphries KH, et al. Determinants of PCI vs. CABG: An inter-provincial comparison. Canadian Cardiovascular Congress. Vancouver, BC; Oct 22–26, 2011. Oral presentation, 530.

Oviedo-Joekes E, Christian WM, Thomas V, Pearce ME, Schechter MT, Spittal PM, Cedar Project Partnership. The Cedar Project: HIV incidence and associated risk factors among young Aboriginal people who use injection and non-injection drugs in two Canadian cities. Canadian Public Health Association 2011 Conference. Montréal, QC; Jun 19–22, 2011.

Oviedo-Joekes E, Christian WM, Pearce ME, Schechter MT, Spittal PM, Cedar Project Partnership. The Cedar Project: Vulnerabilities associated with HIV incidence among young Aboriginal people who use injection and non-injection drugs in two Canadian cities. 20th Annual Canadian Conference on HIV/AIDS Research. Toronto, ON; Apr 14–17, 2011.

` `Centre for Health Evaluation and Outcome Sciences 61 Appendix III

Pearce ME, Patterson K, Moniruzzaman A, Schechter MT, Spittal PM, Cedar Project Partnership. The Cedar Project: Intense crack smoking and HIV vulnerabilities among young Aboriginal people in two Canadian cities. 20th Annual Canadian Conference on HIV/AIDS Research. Toronto, ON; Apr 14–17, 2011.

Pearce ME, Patterson K, Christian WM, Schechter MT, Spittal PM, Cedar Project Partnership. The Cedar Project: Impact of childhood sexual abuse among young Aboriginal men and women who use drugs in two Canadian cities. 3rd North American Congress of Epidemiology. Montréal, QC; Jun 21–24, 2011.

Pearce ME, Patterson K, Oviedo-Joekes E, Thomas V, Schechter MT, Spittal PM, Cedar Project Partnership. The Cedar Project: High frequency crack smoking and HIV risk among young Aboriginal people in two Canadian cities. 3rd North American Congress of Epidemiology. Montréal, QC; Jun 21–24, 2011.

Peets AD, Ayas NT, Stelfox HT, Henrich N, Regehr G. Characterizing cognitive strategies physicians use to optimize performance when sleep-deprived. Research in Medical Education (RIME) Conference. Denver, CO; Nov 2011. Poster presentation.

Phang PT. Accuracy of ERUR vs MR for determination of CRM for rectal cancer. American Society of Colon and Rectal Surgeons, Annual Meeting 2011. Vancouver, BC; May 14–18, 2011. Poster Presentation.

Phang PT. Patient expectations of functional recovery after rectal cancer surgery. American Society of Colon and Rectal Surgeons, Annual Meeting 2011. Vancouver, BC; May 14–18, 2011. Poster presentation.

Phang PT. Rectovaginal and rectourethral fistulas. Canadian Society of Cataract and Refractive Surgery Annual Meeting 2011. London, ON; Sep 15–17, 2011.

Phang PT. Accuracy of ERUR vs MR for determination of CRM for rectal cancer. The American Society of Colon and Rectal Surgeons Annual Meeting. Vancouver, BC; May 14–18, 2011.

Phang PT. TME education in North America. The American Society of Colon and Rectal Surgeons Annual Meeting. Vancouver, BC; May 14–18, 2011.

Rahman M, Kopec J, Anis A, Cibere J, Colfsmith C. The risk of developing cardiovascular diseases among osteoarthritis patients: A prospective study. Canadian Rheumatology Association-Arthritis Health Professions Association Annual General Meeting. Victoria, BC; Mar 29, 2011.

Rahman M, Kopec J, Anis A, Cibere J, Goldsmith C. The risk of developing diabetes among osteoarthritis patients: A prospective study. Canadian Arthritis Network Annual Scientific Conference. Quebec City, QC; Oct 27–29, 2011.

Raval MJ, Heldary B, Kalkias S, Raval D, Phang PT, Brown CJ. Transanal endoscopic microsurgery; outcomes in patients with rectal carcinoma. Canadian Surgery Forum. London, ON; Sept 15–18, 2011.

Recsky M, Phang PT, Raval MJ, Cheung W, Brown CJ. Canadian guidelines for the follow-up of post operative stage II and stage III colorectal cancer patients. Canadian Surgery Forum. London, ON; Sep 15–18, 2011.

Richford C, Corral M, Fitzpatrick S, Millar G, Raudzus J, Simpson P. Delirium: Clinical pathway process and outcomes. Academy of Psychosomatic Medicine Annual Meeting. Phoenix, AZ; Nov 16–20, 2011. Poster presentation (146).

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Rose C, Gill J, Dong J, Chang P, Browne S, Gill JS. Predictable organ allocation—an effective strategy to maintain the benefit of transplantation in the setting of prolonged waiting time. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Sadatsafavi M, Bedouch P, FitzGerald JM, Marra CA, Lynd LD. Asthma-related direct medical costs in British Columbia from 2002 to 2007: a population-based cohort study. Canadian Association for Population Therapeutics, Knowledge to Provide Evidence for Health Care Decision-Makers: Clinical Practice and Research Methodology. Ottawa, ON; Apr 17–19, 2011. Oral presentation, #3.

Sadatsafavi M, Bedouch P, FitzGerald JM, Marra C, Lynd L. Stepping up the controller medication in asthma patients: impact of various treatment options on costs. European Respiratory Society Annual Congress. Amsterdam, Netherlands; Sep 24–28, 2011.

Sadatsafavi M, Bedouch P, FitzGerald JM, Marra CA, Lynd LD. Impact on direct health care costs associated with asthma of various controller medications: results from a population based cohort study. 8th World iHEA Congress in Health Economics/International AllerGen Symposium on Asthma and Economics. Toronto, ON; Jul 10–13, 2011.

Sajobi TT, Lix LM, Huang Y, Sawatzky R, Liu J, Mayo NE. Relative importance measures to detect repriorization response shift. 18th Annual Conference of the International Society for Quality of Life Research. Denver, CO; Oct 26–29, 2011. Available online at: http://www.isoqol.org/2011conference/ac11abstractbook.pdf/.

Lix L, Mayo N, Sawatzky R. Statistical approaches for response shift detection. The 2011 International Society for Quality of Life Research Meeting. Denver, CO; Oct 26–29, 2011. Workshop presentation, WK07.

Sawatzky R, Ratner PA, Kopec JA, Zumbo BD. The accuracy of computerized adaptive tests in heterogeneous populations. 18th Annual Conference of the International Society for Quality of Life Research. Denver, CO; Oct 26–29, 2011. Available online at: http://www.isoqol.org/2011conference/ac11abstractbook.pdf. Oral presentation, #319.

Sayre EC, Kopec JA, Cibere J, Marra CA, Davis J, Esdaile JM. An analysis of daily, weekly and monthly variations in health- related quality of life. 18th Annual Conference of the International Society for Quality of Life Research. Denver, CO; Oct 26–29, 2011.

Schechter M, Romann A, Djurdjev O, Levin A, Beaulieu M. Waiting for initial nephrologist assessment: what are appropriate metrics and benchmarks?—Report on the British Columbia Nephrologists’ Access Study (BCNAS). World Congress of Nephrology 2011. Vancouver, BC; Apr 8–12, 2011.

Schold J, Mariat C, Gill J, Knoll G, Kayler L, Poggio E. Assessing traditionally used surrogate endpoints in kidney transplantation with the Prentice Criteria. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Sedlak T, Izadnegahdar M, Lee M, Gao M, Humphries KH, and Bairey Merz C. Clinical outcomes in patients < 65 years with no obstructive coronary disease on coronary angiogram. American College of Cardiology’s (ACC’s) 61st Annual Scientific Session & Expo. Chicago, IL; Mar 9–11, 2012.

Simpson P, Lau G. Family nursing practice in acute care psychiatry. 5th Annual National Mental Health Nurses Conference, Mental Health Nursing in the 21st Century: Social and Professional Responsibility. Toronto, ON; Oct 28, 2011. Paper presentation.

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Simpson P, Richford C, Corral M, Fitzpatrick S, Millar G, Raudzus J. Knowledge to action (KTA): delirium screening for patients in acute care. 2nd Annual CAPM Conference. Vancouver, BC; Oct 14, 2011. Paper presentation.

Singer J, Samson L, Forbes J, Alimenti A, Lee T, Bitnun A, Money D, Brophy J, Lapointe N, for the Canadian Perinatal HIV Surveillance Program (CPHSP): Perinatal HIV transmission and demographics in Canada. Canadian Association for HIV Research Annual Meeting. Toronto, ON; Apr 14–17, 2011.

Slayter K, Singer J, Lee T, Kayhty H, Haase D, Schlech W, CTN 147 Study Group. Immunologic efficacy of pneumococcal vaccine in HIV patients: Delayed verus immediate immunization CTN 147. Canadian Association for HIV Research Annual Meeting. Toronto, ON; Apr 14–17, 2011.

Spaans JN, Routy JP, Tremblay C, Singer J, Bernard N, Gurunathan S, Sekaly RP, Angel JB. Optimizing the efficiency of therapeutic HIV vaccine trials: A case for CTN 173. J Trials in Vac. Feb 2012.

Spittal PM, Bingham B, Miller C, Pearce ME, Louie M, Schechter MT, Cedar Project Partnership. The Cedar Project: Gendered HIV vulnerabilities associated with needing help injecting among young Aboriginal people who use injection drugs. 20th Annual Canadian Conference on HIV/AIDS Research. Toronto, ON; Apr 14–17, 2011. Poster presentation, P155.

Spittal PM, Bingham B, Miller C, Pearce ME, Louie M, Schechter MT, Cedar Project Partnership. The Cedar Project: HIV risks associated with needing help injecting among young Aboriginal men and women who use injection drugs in two Canadian cities. 20th Annual Canadian Conference on HIV/AIDS Research. Toronto, ON; Apr 14–17, 2011.

Spittal PM, Bingham B, Miller CL, Pearce ME, Louise M, Schechter MT, Cedar Project Partnership. The Cedar Project: Gender difference in HIV risks associated with needing help injecting among young Aboriginal people who use injection drugs in two Canadian cities. Canadian Public Health Association 2011 Conference. Montréal, QC; Jun 19–22, 2011.

Spittal PM, Patel S, Bingham B, Schechter MT, Cedar Project Partnership. The Cedar Project: Gender differences in Hepatitis C Virus (HCV) infection among Aboriginal young people who use injection drugs in two Canadian cities. 3rd North American Congress of Epidemiology. Montréal, QC; Jun 21–24, 2011.

Spittal PM, Pearce ME, Patterson K, Schechter MT, Cedar Project Partnership. The Cedar Project: Over time vulnerabilities associated with sex work involvement among young Aboriginal women who use drugs in Vancouver and Prince George, BC. 3rd North American Congress of Epidemiology. Montréal, QC; Jun 21–24, 2011.

Strehlau V, Torchalla I et al. Mental health and suicidailty in homeless women. 26th Annual Research Day, UBC Psychiatry. Vancouver, BC; May 31, 2011. Oral presentation.

Suzuki M, Sawatzky R, Roberts D. Partnering: An essential strategy for a provincial nurse survey. Sigma Theta Tau International Honor Society of Nursing: 17th Annual Ethel Johns Research Day. Vancouver, BC; Feb 4, 2012.

Tangri N, Stevens L, Griffith J, Djurdjev O, Naimark D, Levin A, Levey A. A new predictive model for progression of chronic kidney disease. World Congress of Nephrology 2011. Vancouver, BC; Apr 8–12, 2011.

Tiwari T, Brown CJ, Raval MJ, Phang PT. Quality of Life (QOL) for operative and nonoperative management of diverticulitis. Canadian Surgery Forum. London, ON; Sep 15–18, 2011.

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Torchalla I, Okoli C, Bottorff J, Qu A, Poole N, Greaves L. Smoking cessation interventions targeted to women: a systematic review. Investigating Tobacco and Gender: iTAG annual Spring Meeting. Vancouver, BC; Apr 8, 2011. WOMEN & HEALTH. 52.1 (2012): 32–54.

Wall GE, Woodle ES, Light J, Franklin C, Joseph J, Rubin M, Goebel J, Baran D, Browne B, Gill J, Shapiro R, Lewis R, Gabardi S, Roberti I, Girnita A, Alloway RR. A prospective multicenter collaborative experience with a proteosome inhibitor based protocol for antibody mediated rejection in kidney transplant: Validation Analysis. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Westerberg B. Avoiding the “deadly sins” of humanitarian missions: How to “do good” better. AAO-HNSF 115th Annual Meeting & OTO EXPO. San Francisco, CA; Sep 11–14, 2011.

Westerberg B. Mental practice in surgical skills: A pilot study on development, validity and implementation for mastoidectomy. 65th Annual Meeting Canadian Society of Otolaryngology Head and Neck Surgery. Victoria, BC; May 22–24, 2011.

Woodle ES, Light J, Franklin C, Morrow WR, Joseph J, Rubin M, Goebel J, Baran D, Browne B, Gill JS, Shapiro R, Eckman P, Mahle W, Lewis R, Gabardi, Roberti I, Girnita A, Wall GE, Alloway RR. A multicenter, prospective, collaborative evaluation of proteasome inhibition for the treatment of antibody mediated rejection in solid organ transplantation. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Woodle ES, Wall GE, Light J, Franklin C, Joseph J, Rubin M, Goebel J, Baran D, Browne B, Gill J, Shapiro R, Lewis R, Gabardi S, Roberti I, Girnita A, Alloway RR. A prospective, multicenter collaborative experience with a proteasome inhibitor based protocol for antibody mediated rejection (AMR): Results in early versus late AM. American Transplant Congress 2011. Philadelphia, PA; Apr 30–May 4, 2011.

Zelichowska J, Chan K, Dunn EC, Srikameswaran S, Geller J. The relationship between ethnicity and patient profiles. Association for Behavioural and Cognitive Therapies Convention. Toronto, ON; Nov 10–13, 2011.

Zelichowska J, Dunn EC, Lockhart A, Srikameswaran S, Geller J. Factors associated with social support in the eating disorders: Exploring relations among support provider characteristics and approaches used. Eating Disorders Research Society 17th Annual Meeting. Edinburgh, Scotland; Sep 22–24, 2011.

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