Hupo 4Th Annual World Congress from Defining the Proteome to Understanding Function
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FINAL PROGRAM HUPO 4TH ANNUAL WORLD CONGRESS FROM DEFINING THE PROTEOME TO UNDERSTANDING FUNCTION Human Proteome Organisation August 29 - September 1, 2005 International Congress Center Munich Munich, Germany www.hupo2005.com ?'%?%TTAN$IGE!D""PDF Top-down sequencing PTM characterization Proteomicsn High-throughput protein ID Biomarker discovery The Power of Proteomics Proteomicsn is Thermo’s commitment to provide you with proven solutions that combine cutting edge instrumentation, expert technical support, and turnkey Resou ics rce m L o ib proteomics applications: e r t ra o rr n n rr y • High-throughput Protein Identification – sensitive 2D-LC/MS and MALDI-MS P methods to rapidly identify all of the proteins in your important samples • Post-translational Modification (PTM) Characterization – MSn determination for definitive phosphorylation site mapping and glycoprotein structure analysis aries. Licensed Materials – Programs of Thermo Electron Corporation. All Rights Reserved. Note: U.S. Government users – RESTRICTED RIGHTS LEGEND. Use, duplication, or disclosure of the Database, Software, and associated materials by the U.S. Government is subject to the restricted rights applicable to commercial computer software • Top-down Protein Sequencing – 100% sequence coverage and unambiguous (under FAR 52.227019 and DFARS 252.227-7013 or parallel regulations). CD61820_E 05/05S isoform identification of intact proteins with the amazing resolution and mass accuracy of the Finnigan™ LTQ FT ™ • Biomarker Discovery – the requisite sensitivity, resolution, and dynamic range to provide a census of the proteins in your sample, including the important low-abundance components Take your proteomics research to the next level. Request Thermo’s Proteomicsn Resource Library CD at www.thermo.com/proteomics4 or contact us to learn more about our commitment to helping you advance your biological research. Tel: 1-800-532-4752 • Email: [email protected] Look closer for answers Analyze • Detect • Measure • Control™ ©2005 Thermo Electron Corporation. AllThermo Electron Corporation. ©2005 rights reserved. All trademarks are the property of and its Thermo Electron Corporation subsidi TABLE OF CONTENTS General Information Committees . .4 Message from the President of the Technical University of Munich . .5 Message from the HUPO President . .6 Message from the Congress Co-Chairs . .6 Congress Information . .7 About Munich . .11 Social Program . .12 Accompanying Persons & Tours . .13 Scientific Program Industry-Sponsored Symposia . .16 How This Program Is Organized . .21 Instructions to Oral and Poster Presenters . .22 Invited Faculty . .23 Detailed Program . .25 Index . .115 Exhibit Directory List of Exhibitors . .129 Exhibit Floor Plan . .130 Exhibitor Details . .136 THIS FINAL PROGRAM IS SUPPORTED IN PART BY BD. Congress Secretariat c/o Events International Conference Planners Inc. 1350 Sherbrooke Street West, Suite 1500 Montreal, Québec, Canada H3G 2T4 Tel.: (514) 286-0855 Fax: (514) 286-6066 E-mail: [email protected] http://www.hupo2005.com/ Local Coordinator www.eurokongress.de Printed in Germany, August 2005 HUPO 2005 • FINAL PROGRAM 3 COMMITTEES Congress Organizing Committee Angelika Görg Arne Skerra, Co-Chair, HUPO 4th Annual World Congress Technische Universität München, Department of Biological Chemistry, Freising, Germany Matthias Mann Co-Chair, HUPO 4th Annual World Congress Naoyuki Taniguchi, Osaka University Graduate School of Medicine, Osaka, John Bergeron Japan HUPO President Mathias Uhlen, Paul Stinson Royal Institute of Technology, Stockholm, Sweden HUPO Director General Walter Weiss, Wehbeh Barghachie Technische Universität München, Department of HUPO Congress Director Proteomics, Freising, Germany Walter Weiss Director of the Scientific Program Committe HUPO Executive Committee John Bergeron, Anthony Zitzmann McGill University, Montreal, Canada Treasurer Samir Hanash, Günter Theßeling Fred Hutchinson Cancer Research Center, Seattle, WA, Congress Consultant United States Sandrine Palcy Matthias Mann, HUPO Education and Training Coordinator University of Southern Denmark, Odense, Denmark; Max- Planck Institute for Biochemistry, Martinsried, Germany Abstract Review Committee Jan Van Oostrum, Rolf Apweiler, Novartis Institutes for Biomedical Research, Basel, EMBL Outstation, European Bioinformatics Institute (EBI), Switzerland Hinxton, Cambridge, United Kingdom Young-Ki Paik, Fuchu He Yonsei University, Yonsei Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing, China; Seoul, Korea Institutes of Biomedical Sciences, Fudan University, Shanghai, China Richard Simpson, Ludwig Institute for Cancer Research, Parkville, Australia Bernhard Kuester, Cellzome AG, Heidelberg, Germany Helmut Meyer, Ruhr University Bochum, Bochum, Germany Gil Omenn, University of Michigan, Ann Arbor, MI, United States Young-Ki Paik, Yonsei University, Yonsei Proteome Research Center, Seoul, Korea Peipei Ping, UCLA School of Medicine, Division of Cardiology, Los Angeles, CA, United States Richard Simpson, Ludwig Institute for Cancer Research, Parkville, Australia 4 HUPO 2005 • FINAL PROGRAM MESSAGES Message from the President of the Technical University of Munich It is a great pleasure for me to host the 4th HUPO World Congress in Munich. Due to the tremendous response from the scientific and industrial communities, the venue of the congress had to be moved from the TUM campus, which is familiar to most of you from the previous international „Proteomic Forum" meetings – organized biannually by Angelika Görg – to the International Congress Center. The hosting of the 4th HUPO World Congress is a significant event for our univer- sity. The TECHNISCHE UNIVERSITÄT MÜNCHEN (TUM) holds a unique position in Europe in terms of the choice of fields it offers. With 400 professors and 8,500 total staff, the TUM covers all areas of the natural and engineering sciences, along with medicine and life sciences. We are ranked foremost among German universities in terms of both total research grant turnover and the number of our guest researchers from all over the world, working at our university with the sup- port of the Alexander von Humboldt Foundation. Moreover, our scientists are currently involved in 17 special research pro- grams financed by the German Research Association. The TUM was founded in 1868 by King Ludwig II in the form of the independent 'Royal Polytechnic'. As Karl Max von Bauernfeind, its first rector, said in his inauguration address, the establishment was founded to "bring the vitalizing sparks of science to bear on technology". Since the time of its foundation, the TUM has earned itself an international reputation in many fields, and accordingly we take the greatest possible care in the selection of our professors. We can point out with pride that a number of Nobel prize winners originate from our university, namely Heinrich Wieland, Hans Fischer, Rudolf Mößbauer, Ernst Otto Fischer, and Robert Huber. Other laureates gained their scientific education at the TUM, as in the case of Konrad Bloch, Klaus von Klitzing, and Wolfgang Ketterle. But scientific success it not only a matter of Nobel prizes and other scientific distinctions but is also expressed by techno- logical developments and new processes and machines. For example, the engineer Carl von Linde (1842-1934), one of our first professors, discovered the liquefaction of air back in 1879, a discovery with revolutionary consequences in all areas of life by introducing refrigeration. Linde's student Rudolf Diesel (1858-1913) was inspired at the then "Technische Hochschule München" to invent the motor engine named after him. Further famous scientists, engineers and inventors of our university include Emil Erlenmeyer (chemistry), Claude Dornier (aircraft engineering), and Willy Messerschmidt (aircraft construction). Recent discoveries and developments in the Life Sciences are spawning new industries and technologies at a breathtaking pace. Life Sciences in general, and proteomics in particular, have a great research and economic potential. I wish the 4th HUPO World Congress every success and would like to cordially invite you to participate in the congress. Prof. Dr. Dr. hc mult. Wolfgang A. Herrmann President of the TECHNISCHE UNIVERSITÄT MÜNCHEN HUPO 2005 • FINAL PROGRAM 5 MESSAGES Message from the HUPO President Message from the Congress Co-Chairs Dear Colleagues, Proteomics is becoming one of the hottest areas of On behalf of the Human research, driven by breath- Proteome Organisation, I taking advances in technolo- would like to welcome you to gy and ever more sophisticat- the HUPO 4th Annual World ed applications to almost Congress in Munich. every area of biology and biomedicine. Proteomics pro- This year’s congress is vides us with data about the entitled "From defining the proteome to understanding func- actual actors in the cell and is thus also in a unique position tion" and it emphasizes the theme of biological function. to integrate data from all of functional genomics into a coherent picture of cellular Building on the success of HUPO’s past congresses, function. So far, proteomics HUPO’s strength and leadership in the field of Proteomics has just given us a taste of and the success of the Proteomic Forum led by Prof. Görg, what will be possible. the congress has generated a great interest that is represented by the participation of delegates from 50 dif- Emphasizing the theme of ferent countries. This tremendous response requiring a biological function, the 4th space