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Publications 2002.Pdf PCL Department Publications - 2002 "A,B,C,D" Francis J, Jung B, Zhang G, Cheng J, Ho W, Burnham WM, Eubanks JH: Kindling induces the mRNA expression of methyl DNA-binding factors in the adult rat hippocampus. Neuroscience 113: 79-87 (2002). Thavendiranathan P, Chow C, Cunnane S, Burnham WM: The effect of the classic ketogenic diet on animal seizure models. Brain Research 959: 206-213 (2002). Edwards HE, Dortok D, Tam J, Won D, Burnham WM: Prenatal Stress Alters Seizure Thresholds and the Development of Kindled Seizures in Infant and Adult Rats. Hormones Behavior 42: 437-447 (2002). Likhodi SS, Burnham WM: On the anticonvulsant effect of acetone and the ketogenic diet. Epilepsia 43: 1596 (2002). Burnham WM : Epilepsy. In: Encyclopedia of Cognitive Science. Nature publishing group. 2: 1-7(2002). Burnham WM : Why are complex partial seizures intractable? In: Burnham WM, Carlen PL, and Hwang PA, (eds). Intractable Seizures Diagnosis, Treatment and Prevention. Plenum Press, 2002, New York, pp. 107-110 Tremblay LK, Naranjo CA, Cardenas L, Herrmann N, Busto UE: Probing brain reward system function in Major Depressive Disorder: Altered response to d-amphetamine. Arch Gen Psychiatry 59: 409-416 (2002). Cardenas L, Tremblay LE, Naranjo CA, Herrmann N, Zack M, Busto UE: Brain reward system activity in major depression and comorbid nicotine dependence. J Pharmacol Exp Ther 302: 1265-1271 (2002). "E,F,G" George SR, O'Dowd BF, Lee SR: G-protein-coupled receptor oligomerization and its potential for drug discovery. Nature Reviews Drug Discovery 1: 808-820 (2002). Lamey M, Thompson M, Varghese G, Chi H, Sawzdargo M, George SR, O'Dowd BF: Distinct residues in the carboxyl tail mediate agonist-induced desensitization and internalization of the human dopamine D-1 receptor. J Biol Chem 277:9415-9421 (2002). PCL Publications (2002) – Page 1 Levac BAR, O'Dowd BF, George SR:Oligomerization of opioid receptors: generation of novel signaling units. Curr Opin Pharmacol 2: 76-81 (2002). Lee DK, George SR, O'Dowd BF: Novel G protein-coupled receptor genes expressed in the brain: Continued discovery of important therapeutic targets. Expert Opin Therap Targets 6:185- 202, (2002). Demchyshyn LL, O'Dowd BF, George SR: Structure of mammalian D1 and D5 dopamine receptors and their function and regulation in cells. In: Sidhu A, Laruelle M, Vernier P, (eds). Dopamine Receptors and Transporters. Marcel Dekker, New York, 2002. Lam V, Findley HW, Reed JC, Freedman MH and Goldenberg GJ: Comparison of DR5 and Fas expression levels relative to the chemosensitivity of acute lymphoblastic leukemia cell lines. Leukemia Res. 26: 503-513 (2002). Basrani B, Santos JM, Tjaderhane L, Grad H, Gorduysus O, Huang J, Lawrence HP, Friedman S: Substantial antimicrobial activity in chlorhexidine-treated human root dentin. Oral Surg Oral Med Oral Pathol Oral Radiol Endon 94: 240-245 (2002). "H" Haas DA: An update on analgesics for the management of acute postoperative dental pain. J Can Dental Assoc 68: 476-482 (2002). Haas DA: An update on local anesthetics in dentistry. J Can Dental Assoc 68: 546-551 (2002). Shojaei AR, Haas DA: Local anesthetic cartridges and latex allergy: a literature review. J Can Dental Assoc 68: 603-607 (2002). Haas DA: Emergency Drugs. Dental Clin North Amer 46: 815-830 (2002). Haas DA: Drugs in Dentistry. Compendium Pharmac Specialties L26-29 (2002). Rosemond E, Peltekova V, Naples M, Thogersen H, Hampson DR: Molecular determinants of high affinity binding to group III metabotropic glutamate receptors. J Biol Chem 277: 7333- 7340 (2002). PCL Publications (2002) – Page 2 Harper PA, Wong JMY, Lam MSM, Okey AB: Polymorphisms in the human AH receptor. Chem-Biol Interactions 141:161-187 (2002). "I, J" Jorge-Nebert LF, Eichelbaum M, Griese E-U, Inaba T, Arias TD: Analysis of six SNPs of NAT2 in Ngawbe and Embera Amerindians of Panama and determination of the Embera acetylation phenotype employing caffeine. Pharmaogenetics 12: 39-45 (2002). Fukuen S, Fukuda T, Maune H, Ikenaga Y, Yamamoto I, Inaba T, Azuma J: Novel detection assay by PCR-RFLP and frequency of CYP3A5 SNPs, CYP3A5*3 and *6, in a Japanese population. Pharmacogenetics 12: 331-334 (2002). Matsumoto S, Ding LR, Ishii M, Fischer NE, Inaba T: The interaction of human and bovine serum proteins with CYP3A in human liver microsomes: inhibition of testosterone 6beta- hydroxylation by albumin, alpha-globulins, alpha-1-acid glycoprotein and gamma-globulins. Tox Letters 136: 33-41 (2002). Fukuen S, Fukuda T, Matsuda H, Sumida A, Yamamoto I, Inaba T, Azuma J. Identification of the novel splicing variants for the hPXR in human livers. Biochem Biophys Res Comm 298: 433- 438 (2002). Costei A, Kozer E, Ho T, Ito S, Koren G. Perinatal outcome following third trimester exposure to paroxetine. Arch Ped Adoles Med. 156:1129-1132 (2002). "K" Khanna JM, Morato GS, Kalant H: Effect of NMDA antagonists, antagonists, an NMDA agonist, and serotonin depletion on acute tolerance to ethanol. Pharmacol Biochem Behav: 72: 291-298 (2002). Kalant H: Editorial: Tolérance et dépendance - une entité commune, ou distinctive pour chaque drogue? Alcoologie et Addictologie 24: 204-206 (2002) Kalant H: Addiction. In: Adelman G, Smith BH (eds.). Encyclopedia of Neuroscience, 3rd ed. New York: Elsevier Science (2002). PCL Publications (2002) – Page 3 Kalow W: Both populations and individuals are evolutionary targets: Pharmacogenomic and cultural indicators. The Pharmacogenomics Journal. 2: 12-19 (2002). Kalow W: Pharmacogenetics and personalized medicine. Fund Clin Pharmacol 16: 337-342 (2002). Sy SKB, Ciaccia A, Li W, Roberts EA, Okey A, Kalow W, Tang BK: Modeling of human hepatic CYP3A4 enzyme kinetics, protein, and mRNA indicates deviation from log-normal distribution in CYP3A4 gene expression. Eur J Clin Pharmacol 58: 357-365 (2002). Sy SKB, Tang BK, Johnston JA, Roberts EA, Kalow W: Multivariate cluster analysis of a human hepatic cytochrome P450 database. Eur J Clin Pharmacol 58: 554-562 (2002). Khanna JM, Morato GS, Kalant H: Effect of NMDA antagonists, antagonists, an NMDA agonist, and serotonin depletion on acute tolerance to ethanol. Pharmacol Biochem Behav 72: 291-298 (2002). Kish SJ: How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy? Pharmacol Biochem Behav 71: 845-855 (2002). Ross BM, Moszczynska A, Peretti FJ, Adams V, Schmunk GA, Kalasinsky KS, Ang L, Mamalias N, Turenne SD, Kish SJ: Decreased activity of brain phospholipid metabolic enzymes in human users of cocaine and methamphetamine. Drug Alcohol Depend 67: 73-79 (2002). Fitzmaurice P, Ang L, Guttman M, Rajput A, Furukawa Y, Kish SJ: Brain aconitase activity is not decreased in progressive supranuclear palsy. Neurology 59:137-138 (2002). Furukawa Y, Kapatos G, Haycock JW, Worsley J, Wong H, Kish SJ, Nygaard TG: Brain biopterin and tyrosine hydroxylase in asymptomatic dopa-responsive dystonia. Annals Neurology 51:637-641 (2002). Furukawa Y, Vigouroux S, Wong H, Guttman M, Rajput AH, Ang L, Briand M, Kish SJ, Briand Y: Brain proteosomal function in sporadic Parkinson=s disease and related disorders. Annals Neurology 51:779-782 (2002). PCL Publications (2002) – Page 4 Koren G, Cohn T, Chitayat D, Kapur B, Remington G, Reid DM, Zipursky RB: Use of Atypical Antipsychotics During Pregnancy and the Risk of Neural Tube Defects in Infants. Am J Psychiatry. 159: 136-137 (2002). Koren G, Cohn T, Chitayat D, Kapur B, Remington G, Reid DM, Zipursky RB: Use of atypical antipsychotics during pregnancy and the risk of neural tube defects in infants. Op cit. 159: 136-7 (2002) Nulman I, Rovet J, Stewart DE, Wolpin J, Pace-Asciak P, Shuhaiber S, Koren G: Child development following exposure to TCA of fluoxetine throughout fetal life:a prospective, controlled study. Op cit. 159: 1189-95 (2002). Koren G, Boskovic R, Hard M, Maltepe C, Navioz Y, Einarson A: Motherisk-PUQE (pregnancy-unique quantification of emesis and nausea) scoring system for nausea and vomiting of pregnancy. Am J Obstet Gynecol. 185: S228-31 (2002). Magee LA, Chandra K, Mazzotta P, Stewart D, Koren G, Guyatt GH: Development of a health-related quality of life instrument for nausea and vomiting of pregnancy. Op cit 185: S323-8 (2002). Koren G, Levichek Z: The teratogenicity of drugs for nausea and vomiting of pregnancy: perceived versus true risk. Op cit. 185: S248-52 (2002). Magee LA, Mazzotta P, Koren G: Evidence-based view of safety and effectiveness of pharmacologic therapy for nausea and vomiting of pregnancy. (NVP). Op cit. 185: S256-61 (2002 Kozer E, Nikfar S, Costei A, Boscovic R, Nulman I, Koren G: Aspirin consumption during the first trimester of pregnancy and congenital anomalies: A meta-analysis. Op cit. 187: 1623-30 (2002). Koren G: Drinking alcohol while breastfeeding. Will it harm my baby? Can Fam Physician. 48:39-41 (2002). Chandra K, Einarson A, Koren G: Taking ginger for nausea and vomiting during pregnancy. Op cit 48:1441-2 (2002). Goldman RD, Koren G: Influenza vaccination during pregnancy. Op cit 48: 1768-9 (2002). Yagev Y, Koren G: Eating fish during pregnancy. Risk of exposure to toxic levels of methylmercury. Op cit 48:1619-21 (2002). Levichek Z, Atanackovic G, Oepkes D, Maltepe C, Einarson A, Magee L, Koren G: Nausea and vomiting of pregnancy. Evidence based treatment algorithm. Op cit. 48: 267-8 (2002). Liaschko A, Koren G: Cystic fibrosis during pregnancy. Op cit 48: 463-4 (2002). PCL Publications (2002) – Page 5 Abadi S, Einarson A, Koren G: Use of warfarin during pregnancy. Op cit 48: 695-7 (2002). Einarson A, Koren G: Bacterial vaginosis during pregnancy. Should we screen for and treat it? Op cit. 48: 877-8 (2002). Einarson A, Portnoi G, Koren G: Update on Motherisk. Seven years of questions and answers. Op cit. 48:1301-4 (2002).
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