Bronchial Hygiene
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Effects of Calcium on Intestinal Mucin: Implications for Cystic Fibrosis
27. Takcbayi~shi.S.. (;robe. II . von B;~ssca~t/.D. H.. and rliormnn. 11. Ultrastruc- prepnratlon.) tural a\pects of veihel .llteratlon\ In homoc!\t~nur~a.V~rcha\r'r Arch. Aht. .A 33 Wong. P. W. K.. Scliworl. V . and Komro~er.(i. M.: The b~os!nthc\~\of P;~thol Anat . 1154- 4 (1071). c)st:~thlonrnc In pntlcntc s~thhornoc!\tinur~,~. Ped~at.Rer . 2- 149 (196x1. 28. T:~ndler. H. T.. I:rlandson. R. A,, and Wbnder. E. 1.. Rihol1;lvln and mou\c 34 'The authors would l~kcto thank K. Curleq, N. Becker, and k.Jaros~u\ for thcir hepatic cell structure and funct~on.hmer. J. Pnthol.. 52 69 (1968). techn~cal:Is\l\tancc and Dr\. B. Chomet. Orville T B:llle!. and Mar) B. 29. Ti~nikawa, L.: llltrastructurnl A\pect\ of the I iver and Its I)~sordcr\(Igaker Buschman for the~ruggehtlona In the ~ntcrpretation\of braln and Iner electron Shoin. I.td.. Tok!o. 1968). micrograph\. 30. Uhlendorl, B. W.. Concrl!. E. R.. and Mudd. S. H.: tlomoc!st~nur~a:Studle, In 35 Th~sstud! &a\ \upported b! Publrc Health Servlcc Kese;~rch Grant no. KO1 tissue culture. Pediat. Kes.. 7: 645 (1073). N5OX532NlN and a grant from the Illino~\Department of Mental llealth. 31. Wong. P. W. K.. and Fresco. R.: T~\suec!\tathlon~nc in mice trei~tedw~th 36 Requests for reprint\ should be i~ddressed to: Paul W. K. Wong. M.D.. cystelne and homoser~ne.Pedlat. Res . 6 172 (1972) Department of Ped~atric.Prcsh!tcr~an-St. -
Lung Abscess: Analysis of 252 Consecutive Cases Diagnosed Between 1968 and 2004
136 Moreira JS, Camargo JJP, Felicetti JC, Goldenfun PR, Moreira ALS, Porto NS Artigo Original Abscesso pulmonar de aspiração: análise de 252 casos consecutivos estudados de 1968 a 2004* Lung abscess: analysis of 252 consecutive cases diagnosed between 1968 and 2004 JOSÉ DA SILVA MOREIRA1, JOSÉ DE JESUS PEIXOTO CAMARGO2, JOSÉ CARLOS FELICETTI2, PAULO ROBERTO GOLDENFUN3, ANA LUIZA SCHNEIDER MOREIRA4, NELSON DA SILVA PORTO2 RESUMO Objetivo: Apresentar a experiência de um serviço especializado em doenças respiratórias no manejo de casos de abscesso pulmonar de aspiração. Métodos: Descrevem-se aspectos diagnósticos e resultados terapêuticos de 252 casos consecutivos de pacientes com abscesso de pulmão, hospitalizados de 1968 a 2004. Resultados: Dos 252 casos, 209 ocorreram em homens e 43 em mulheres, com média de idade de 41,4 anos. Eram alcoolistas 70,2% dos pacientes. Tosse, expectoração, febre e comprometimento do estado geral ocorreram em mais de 97% dos casos, 64% tinham dor torácica, 30,2% hipocratismo digital, 82,5% apresentavam dentes em mau estado de conservação, 78,6% tiveram episódio de perda de consciência e 67,5% apresentavam odor fétido de secreções broncopulmonares. Em 85,3% dos casos as lesões localizavam-se nos segmentos posterior de lobo superior ou superior de lobo inferior, 96,8% delas unilateralmente. Em 24 pacientes houve associação de empiema pleural (9,5%). Flora mista foi identificada em secreções broncopulmonares ou pleurais em 182 pacientes (72,2 %). Todos os doentes foram inicialmente tratados com antibióticos (principalmente penicilina ou clindamicina) e 98,4 % deles foram submetidos à drenagem postural. Procedimentos cirúrgicos foram efetuados em 52 (20,6%) pacientes (24 drenagens de empiema, 22 ressecções pulmonares e 6 pneumostomias). -
Respiratory – Aspiration Precautions SECTION: 9.01 Strength of Evidence Level: 3
Respiratory – Aspiration Precautions SECTION: 9.01 Strength of Evidence Level: 3 PURPOSE: 4. Consult speech therapist for patients with Implement and educate patient/caregiver on precautions dysphagia, as needed, and as ordered by that prevent aspiration. healthcare provider. 5. Consult dietitian for diet evaluation, as needed CONSIDERATIONS: (requires physician’s order). 6. If patient receiving enteral feedings, See Digestive - 1. Precautions should be taken with all patients who Gastrostomy or Jejunostomy Tube Feeding. are unable to protect their airway to prevent the 7. Monitor patient when eating/drinking: involuntary inhalation of foreign substances, such a. Instruct family or caregiver to do the same. as gastric contents, oropharyngeal secretions, b. Observe adequacy of swallowing. food or fluids, into the tracheobronchial passages. c. SN: order ST eval for tube fed patients for 2. Patients at particular risk for aspiration include those swallow eval as appropriate. whose normal protective mechanisms are impaired. 8. Maintain calm environment when the patient is 3. Major risk factors include: eating or drinking. a. Decreased level of consciousness (confusion, 9. If patient is unable to manage own oral secretions, coma, sedation). nasopharyngeal suctioning may be indicated, b. Documented previous episode of aspiration. consult with healthcare provider and refer to c. Neuromuscular disease and structural nasopharyngeal suctioning policy as needed. abnormalities of the aerodigestive tract. 10. Keep wire cutters at HOB of patient with wired jaws d. Depressed protective reflexes (cough or gag). and instruct patient and caregiver in use. e. Presence of an endotracheal tube. 11. Notify healthcare provider immediately for any signs f. Persistently high gastric residual volumes. -
Chest Physiotherapy Page 1 of 10
UTMB RESPIRATORY CARE SERVICES Policy 7.3.9 PROCEDURE - Chest Physiotherapy Page 1 of 10 Chest Physiotherapy Effective: 10/12/94 Revised: 04/05/18 Formulated: 11/78 Chest Physiotherapy Purpose To standardize the use of chest physiotherapy as a form of therapy using one or more techniques to optimize the effects of gravity and external manipulation of the thorax by postural drainage, percussion, vibration and cough. A mechanical percussor may also be used to transmit vibrations to lung tissues. Policy Respiratory Care Services provides skilled practitioners to administer chest physiotherapy to the patient according to physician’s orders. Accountability/Training • Chest Physiotherapy is administered by a Licensed Respiratory Care Practitioner trained in the procedure(s). • Training must be equivalent to the minimal entry level in the Respiratory Care Service with the understanding of age specific requirements of the patient population treated. Physician's A written order by a physician is required specifying: Order Frequency of therapy. Lung, lobes and segments to be drained. Any physical or physiological difficulties in positioning patient. Cough stimulation as necessary. Type of supplemental oxygen, and/or adjunct therapy to be used. Indications This therapy is indicated as an adjunct in any patient whose cough alone (voluntary or induced) cannot provide adequate lung clearance or the mucociliary escalator malfunctions. This is particularly true of patients with voluminous secretions, thick tenacious secretions, and patients with neuro- muscular disorders. Drainage positions should be specific for involved segments unless contraindicated or if modification is necessary. Drainage usually in conjunction with breathing exercises, techniques of percussion, vibration and/or suctioning must have physician's order. -
A Comparison of the Therapeutic Effectiveness
A COMPARISON OF THE THERAPEUTIC EFFECTIVENESS AND ACCEPTANCE OF CONVENTIONAL POSTURAL DRAINAGE AND PERCUSSION, INTRAPULMONARY PERCUSSIVE VENTILATION AND IDGH FREQUENCY CHEST WALL COMPRESSION IN HOSPITALIZED PATIENTS WITH CYSTIC FIBROSIS A Thesis Presented in Partial Fulfillment of the Requirements for the Degree Master of Science in the Graduate School of The Ohio State University By Sarah Meredith Varekojis, B.S. ***** The Ohio State University 1998 Master's Examination Committee: Approved by Mr. F. Herbert Douce, Adviser Dr. Phil Hoberty Adviser Dr. Karen McCoy School of Allied Medical Professions ABSTRACT A significant clinical manifestation of cystic fibrosis is abnormally abundant and viscous bronchial secretions. This leads to obstruction of bronchi in the lungs and predisposes the individual to chronic pulmonary infections. Bronchopulmonary hygiene is an essential part of the care of a patient with cystic fibrosis in order to enhance mucociliary clearance. Currently, several modalities of therapy are available, including high frequency chest wall compressions (HFCC), intrapulmonary percussive ventilation (IPV) and conventional postural drainage and percussion (PD&P). This study was designed to directly compare the sputum produced with HFCC, IPV and PD&P. Twenty-seven hospitalized patients were recruited for the study. Each patient received two consecutive days of each form of therapy in random order. All therapies were delivered three times a day for thirty minutes. Any sputum produced during the treatment time was expectorated and collected. Sputum was collected for a total of sixty minutes: fifteen minutes before the treatment during aerosol delivery, during the thirty minute treatment and for fifteen minutes post therapy. Sputum expectorated during each session was weighed wet and then dried and weighed again. -
In Vitro Modelling of the Mucosa of the Oesophagus and Upper Digestive Tract
21 Review Article Page 1 of 21 In vitro modelling of the mucosa of the oesophagus and upper digestive tract Kyle Stanforth1, Peter Chater1, Iain Brownlee2, Matthew Wilcox1, Chris Ward1, Jeffrey Pearson1 1NUBI, Newcastle University, Newcastle upon Tyne, UK; 2Applied Sciences (Department), Northumbria University, Newcastle upon Tyne, UK Contributions: (I) Conception and design: All Authors; (II) Administrative support: All Authors; (III) Provision of study materials or patients: All Authors; (IV) Collection and assembly of data: All Authors; (V) Data analysis and interpretation: All Authors; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Kyle Stanforth. NUBI, Medical School, Framlington Place, Newcastle University, NE2 4HH, Newcastle upon Tyne, UK. Email: [email protected]. Abstract: This review discusses the utility and limitations of model gut systems in accurately modelling the mucosa of the digestive tract from both an anatomical and functional perspective, with a particular focus on the oesophagus and the upper digestive tract, and what this means for effective in vitro modelling of oesophageal pathology. Disorders of the oesophagus include heartburn, dysphagia, eosinophilic oesophagitis, achalasia, oesophageal spasm and gastroesophageal reflux disease. 3D in vitro models of the oesophagus, such as organotypic 3D culture and spheroid culture, have been shown to be effective tools for investigating oesophageal pathology. However, these models are not integrated with modelling of the upper digestive tract—presenting an opportunity for future development. Reflux of upper gastrointestinal contents is a major contributor to oesophageal pathologies like gastroesophageal reflux disease and Barratt’s oesophagus, and in vitro models are essential for understanding their mechanisms and developing solutions. -