Choose to Be Informed About Chronic Pelvic Pain Conditions
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Pelvic Inflammatory Disease -PID Examination and STI Screening
How do I get tested for PID? What about my partner? a guide to PID is diagnosed by a medical assessment/ As PID can be caused by a sexually transmitted Pelvic Inflammatory Disease -PID examination and STI screening. There is no one infection it is important that all current partners simple test. are tested for STIs and are treated with antibiotics You can still have PID even if your STI screen is too (even if their STI tests are negative). negative. Sometimes ex partners will need to be tested too If your doctor suspects PID you will be advised - you will be advised about this. to have a course of antibiotics. This is because the consequences of leaving PID untreated or not When can I have sex again? treating promptly (see below) can be serious. It’s best you don’t have sex at all (not even with a We also need to make sure you are not pregnant condom and not even any oral sex) until you and – please tell your doctor if you think you could be your partner have finished your antibiotics. pregnant. What happens if my PID is left untreated? How is PID treated? Untreated PID can cause serious problems: It is important to get treated quickly to reduce the Persistent or recurrent bouts of pelvic pain risk of complications. Infertility PID is treated with a mixture of antibiotics to cover An ectopic pregnancy (this is a serious condition the most likely infections. requiring urgent surgery) The treatment course is usually for 2 weeks. Pelvic abscess The treatment is free and issued to you directly in Persistent or recurrent bouts of pelvic or the clinic. -
About Ovarian Cancer Overview and Types
cancer.org | 1.800.227.2345 About Ovarian Cancer Overview and Types If you have been diagnosed with ovarian cancer or are worried about it, you likely have a lot of questions. Learning some basics is a good place to start. ● What Is Ovarian Cancer? Research and Statistics See the latest estimates for new cases of ovarian cancer and deaths in the US and what research is currently being done. ● Key Statistics for Ovarian Cancer ● What's New in Ovarian Cancer Research? What Is Ovarian Cancer? Cancer starts when cells in the body begin to grow out of control. Cells in nearly any part of the body can become cancer and can spread. To learn more about how cancers start and spread, see What Is Cancer?1 Ovarian cancers were previously believed to begin only in the ovaries, but recent evidence suggests that many ovarian cancers may actually start in the cells in the far (distal) end of the fallopian tubes. 1 ____________________________________________________________________________________American Cancer Society cancer.org | 1.800.227.2345 What are the ovaries? Ovaries are reproductive glands found only in females (women). The ovaries produce eggs (ova) for reproduction. The eggs travel from the ovaries through the fallopian tubes into the uterus where the fertilized egg settles in and develops into a fetus. The ovaries are also the main source of the female hormones estrogen and progesterone. One ovary is on each side of the uterus. The ovaries are mainly made up of 3 kinds of cells. Each type of cell can develop into a different type of tumor: ● Epithelial tumors start from the cells that cover the outer surface of the ovary. -
Pelvic Inflammatory Disease (PID) PELVIC INFLAMMATORY DISEASE (PID)
Clinical Prevention Services Provincial STI Services 655 West 12th Avenue Vancouver, BC V5Z 4R4 Tel : 604.707.5600 Fax: 604.707.5604 www.bccdc.ca BCCDC Non-certified Practice Decision Support Tool Pelvic Inflammatory Disease (PID) PELVIC INFLAMMATORY DISEASE (PID) SCOPE RNs (including certified practice RNs) must refer to a physician (MD) or nurse practitioner (NP) for all clients who present with suspected PID as defined by pelvic tenderness and lower abdominal pain during the bimanual exam. ETIOLOGY Pelvic inflammatory disease (PID) is an infection of the upper genital tract that involves any combination of the uterus, endometrium, ovaries, fallopian tubes, pelvic peritoneum and adjacent tissues. PID consists of ascending infection from the lower-to-upper genital tract. Prompt diagnosis and treatment is essential to prevent long-term sequelae. Most cases of PID can be categorized as sexually transmitted and are associated with more than one organism or condition, including: Bacterial: Chlamydia trachomatis (CT) Neisseria gonorrhoeae (GC) Trichomonas vaginalis Mycoplasma genitalium bacterial vaginosis (BV)-related organisms (e.g., G. vaginalis) enteric bacteria (e.g., E. coli) (rare; more common in post-menopausal people) PID may be associated with no specific identifiable pathogen. EPIDEMIOLOGY PID is a significant public health problem. Up to 2/3 of cases go unrecognized, and under reporting is common. There are approximately 100,000 cases of symptomatic PID annually in Canada; however, PID is not a reportable infection so, exact -
Different Influences of Endometriosis and Pelvic Inflammatory Disease On
International Journal of Environmental Research and Public Health Article Different Influences of Endometriosis and Pelvic Inflammatory Disease on the Occurrence of Ovarian Cancer Jing-Yang Huang 1,2,†, Shun-Fa Yang 1,2 , Pei-Ju Wu 1,3,†, Chun-Hao Wang 4,†, Chih-Hsin Tang 5,6,7 and Po-Hui Wang 1,2,3,8,* 1 Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan; [email protected] (J.-Y.H.); [email protected] (S.-F.Y.); [email protected] (P.-J.W.) 2 Department of Medical Research, Chung Shan Medical University Hospital, Taichung 402, Taiwan 3 Department of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung 402, Taiwan 4 Department of Medicine, National Taiwan University, Taipei 106, Taiwan; [email protected] 5 School of Medicine, China Medical University, Taichung 404, Taiwan; [email protected] 6 Chinese Medicine Research Center, China Medical University, Taichung 404, Taiwan 7 Department of Medical Laboratory Science and Biotechnology, College of Medical and Health Science, Asia University, Taichung 413, Taiwan 8 School of Medicine, Chung Shan Medical University, Taichung 402, Taiwan * Correspondence: [email protected] † Equal contributions as first authors. Abstract: To compare the rate and risk of ovarian cancer in patients with endometriosis or pelvic inflammatory disease (PID). A nationwide population cohort research compared the risk of ovarian cancer in 135,236 age-matched comparison females, 114,726 PID patients, and 20,510 endometriosis patients out of 982,495 females between 1 January 2002 and 31 December 2014 and ended on the date Citation: Huang, J.-Y.; Yang, S.-F.; of confirmation of ovarian cancer, death, or 31 December 2014. -
Pelvic Inflammatory Disease (PID) Brown Health Services Patient Education Series
Pelvic Inflammatory Disease (PID) Brown Health Services Patient Education Series the uterine lining to treat abnormal What is PID? bleeding) PID (pelvic inflammatory disease) is ● PID risk from insertion of an IUD inflammation caused by infections ascending (intrauterine device) – occurs in the first 3 weeks post insertion from the vagina or cervix to the upper genital ● Abortion tract. This includes the lining of the uterus, the ovaries, the fallopian tubes, the uterine wall Why is it important to treat PID? and the uterine ligaments that hold these ● structures in place. PID is the most common serious infection of women aged 16 to 25 years What causes it? of age ● Untreated pelvic infections may cause Most cases of PID are caused by sexually adhesions in the fallopian tubes, which transmitted infections (STIs). The disease can be may lead to infertility caused by many different organisms or ● 1 in 4 women with acute PID develop combinations of organisms, but is frequently future problems such as ectopic caused by gonorrhea and chlamydia. Although pregnancy or chronic pelvic pain from Bacterial Vaginosis (BV) is associated with PID, adhesions whether the incidence of PID can be reduced by What are the symptoms? identifying and treating people with vaginas with BV is unclear. If you notice abnormal ● Painful intercourse could be the first discharge and a fishy vaginal odor (signs of BV) sign of infection ● you should be evaluated at Health Services. Pain and tenderness involving the lower abdomen, cervix, uterus and ovaries PID may also occur following procedures that ● Fever and chills create an open wound where infectious ● Nausea and/or diarrhea organisms can more easily enter, such as: ● Abnormal vaginal bleeding or discharge ● Biopsy from the lining of the uterus Early treatment can usually prevent these ● D & C (dilation and curettage – a problems. -
Prohibitin-Induced Obesity Leads to Anovulation and Polycystic Ovary in Mice Sudharsana Rao Ande1,*, Khanh Hoa Nguyen1,*, Yang Xin Zi Xu1 and Suresh Mishra1,2,‡
© 2017. Published by The Company of Biologists Ltd | Biology Open (2017) 6, 825-831 doi:10.1242/bio.023416 RESEARCH ARTICLE Prohibitin-induced obesity leads to anovulation and polycystic ovary in mice Sudharsana Rao Ande1,*, Khanh Hoa Nguyen1,*, Yang Xin Zi Xu1 and Suresh Mishra1,2,‡ ABSTRACT and Dunphy, 2014). Along with the increase in the prevalence of Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder overweight and obesity in women, there has been an increase in and the most common cause of female infertility. However, its etiology anovulatory infertility (Giviziez et al., 2016). Androulakis et al. and underlying mechanisms remain unclear. Here we report that a (2014) reported that visceral adiposity index is related to the severity transgenic obese mouse (Mito-Ob) developed by overexpressing of anovulation and other clinical features in women with polycystic prohibitin in adipocytes develops polycystic ovaries. Initially, the ovaries. An increase in subcutaneous abdominal fat has also been female Mito-Ob mice were equally fertile to their wild-type littermates. associated with anovulation in women with obesity (Kuchenbecker The Mito-Ob mice began to gain weight after puberty, became et al., 2010). It is believed that anovulatory infertility accounts for significantly obese between 3-6 months of age, and ∼25% of them 25-50% of causes of female infertility (Weiss and Clapauch, 2014). had become infertile by 9 months of age. Despite obesity, female One of the main causes of anovulatory infertility is polycystic Mito-Ob mice maintained glucose homeostasis and insulin sensitivity ovaries (Ben-Shlomo et al., 2008; Messinis et al., 2015). -
LNG-IUS) in Patients Affected by Menometrorrhagia, Dysmenorrhea and Adenomimyois: Clinical and Ultrasonographic Reports
European Review for Medical and Pharmacological Sciences 2021; 25: 3432-3439 The treatment with Levonorgestrel Releasing Intrauterine System (LNG-IUS) in patients affected by menometrorrhagia, dysmenorrhea and adenomimyois: clinical and ultrasonographic reports F. COSTANZI, M.P. DE MARCO, C. COLOMBRINO, M. CIANCIA, F. TORCIA, I. RUSCITO, F. BELLATI, A. FREGA, G. COZZA, D. CASERTA Department of Surgical and Medical Sciences and Translational Medicine, Sant’Andrea University Hospital, Sapienza University of Rome, Rome, Italy Abstract. – OBJECTIVE: Adenomyosis is p=0.025; p=0.014). The blood loss decreased the consequence of the myometrial invasion significantly in both the cohorts (p<0.001) and by endometrial glands and stroma. Transvag- particularly in adenomyotic patients. Pain relief inal ultrasonography plays a decisive role in was observed in all the patients (p<0.001). the diagnosis and monitoring of this patholo- CONCLUSIONS: LNG-IUS can be considered gy. Our study aims to evaluate the efficacy of an effective treatment for managing symptoms LNG-IUS (Levonorgestrel Releasing Intrauter- and improving uterine morphology. ine System) as medical therapy. We analyzed both clinical symptoms and ultrasonograph- Key Words: ic aspects of menometrorrhagia and dysmen- Benign disease of uterus, Dysmenorrhea, Gyne- orrhea in patients with adenomyosis and the cologic imaging, Leiomyomas of the uterus/adeno- control group. myosis. PATIENTS AND METHODS: A prospective co- hort study was carried out on 28 patients suf- fering from symptomatic adenomyosis treat- ed with LNG-IUS. Adenomyosis was diagnosed Introduction through transvaginal ultrasonography by an ex- pert sonographer. A control group of 27 symp- Adenomyosis is a benign gynecological dis- tomatic patients (menorrhagia and dysmenor- ease with a large variety of clinical manifestation; rhea) without a transvaginal ultrasonograph- the most frequent include menorrhagia, metror- ic diagnosis of adenomyosis was treated in the rhagia, dysmenorrhea and chronic pelvic pain1. -
Endometriosis
www.pelvicpain.org All information, content, and material of this website / handout is for informational purposes only and are not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. The information is not intended to recommend the self-management of health problems or wellness. It is not intended to endorse or recommend any particular type of medical treatment. Should the reader have any health care related questions, that person should promptly call or consult your physician or healthcare provider. This information should not be used by any reader to disregard medical and/or health related advice or provide a basis to delay consultation with a physician or a qualified healthcare provider. Endometriosis Endometriosis occurs when tissue that is similar to the lining of the uterus (endometrium) grows in other parts of the body and causes chronic inflammation that can cause scarring. It affects an estimated 5-10% of all women. It is most commonly found in the pelvic cavity and ovaries. Less commonly, these lesions may grow on the intestines and bladder, and rarely in the lungs or other body locations. Growths of endometriosis are almost always benign (not cancerous). Symptoms The most common symptom is pain in the pelvis, lower abdomen, or lower back. Pain is most often during the menstrual cycle, but women may have pain at other times. Not everyone with endometriosis has pain. Other symptoms include difficulty getting pregnant, pain during or after sex, pain with bowel movements or urination, constipation, diarrhea and bloating (often around the menstrual cycle). -
Prohibitin-Induced Obesity Leads to Anovulation and Polycystic Ovary in Mice
Prohibitin-induced obesity leads to anovulation and polycystic ovary in mice Sudharsana Rao Ande†1, Khanh Hoa Nguyen†1, Yang Xin Zi Xu1, Suresh Mishra*1,2 Department of Internal Medicine1, Department of Physiology & Pathophysiology2, University of Manitoba, Winnipeg, Canada Key words: Transgenic models, periovarian adipose tissue, cystic ovary, female infertility. † Contributed equally to this manuscript. * Correspondence Suresh Mishra, Ph.D. Department of Internal Medicine University of Manitoba Rm 843, John Buhler Research Centre 715 McDermot Avenue Winnipeg, MB R3E 3P4 Canada Ph. 204 977 5629 Fax: 204 789 3988 E-mail: [email protected] © 2017. Published by The Company of Biologists Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction Biology Open • Advance article in any medium provided that the original work is properly attributed. ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and the most common cause of female infertility. However, the etiology of the disease and the mechanisms by which this disorder progress remain unclear. Here we report that a transgenic obese mouse (Mito-Ob) developed by overexpressing prohibitin in adipocytes develops polycystic ovaries. Initially, the female Mito-Ob mice were equally fertile to their wild-type littermates. Mito-Ob mice begin to gain weight after puberty, become significantly obese between 3-6 months of age, and roughly 25% of them become infertile by 9 months of age. Despite obesity, female Mito-Ob mice maintained glucose homeostasis and insulin sensitivity similar to their wild- type littermates. -
Gynecology Revised: 11/2013
Emergency Medical Training Services Emergency Medical Technician – Paramedic Program Outlines Outline Topic: Gynecology Revised: 11/2013 21 questions on exam 8 from this outline • Menstruation - normal periodic discharge of blood, mucus, and cellular debris from uterus. The normal menstrual cycle lasts about 28 days. 25 to 60mL average flow. Flow lasts usually 4 to 6 days. Lining of the uterus is called endometrium. Onset of menses (menarche) begins around 12 years of age. Menopause starts at age 47 on average. But can range from 30 to 60 years of age. Estrogen stimulates endometrium to grow and increase in thickness. • Ovaries contain about 5 million cells to make oocytes (immature ova/eggs). At puberty 350,000 are present. In a lifetime the ovary will release 400 through menstruation • The release of the egg is termed ovulation. • The pituitary released FSH to stimulate the ovaries to produce estrogen. As a result of the estrogen builds up in blood stream just before ovulation the pituitary releases luteinizing hormone to initiate the release of eggs. • Up to seven days after ovulation (day 21) the uterus is ready to receive an embryo if fertilization has happened. • Recap: Day 14 ovulation. Up to day 21 fertilization window, day 22 thru 28 period if not pregnant. GYN emergencies are classified as: Non-traumatic • PID - infection entered the pelvis cavity. Most common causes are non-sterile exam equipment and if sexually transmitted is N. Gonorrhea and Chlamydia. Lower abdominal pain, hurts with sex, vaginal discharge and additional bleeding after period is over. Antibiotic therapy is needed. • Ovarian cyst - can be a bleeding/shock emergency. -
Management of Primary Dysmenorrhea in Young Women with Frameless LNG-IUS
Open Access Journal of Contraception Dovepress open access to scientific and medical research Open Access Full Text Article REVIEW Management of primary dysmenorrhea in young women with frameless LNG-IUS Dirk Wildemeersch1 Abstract: The objective of this paper is to discuss the potential advantages of intrauterine treat- Sohela Jandi2 ment with a frameless levonorgestrel (LNG)-releasing intrauterine system (IUS) in young women Ansgar Pett2 presenting with primary dysmenorrhea associated with heavy menstrual bleeding. The paper is Thomas Hasskamp3 based on clinical reports of 21 cases of primary and secondary dysmenorrhea treated with the frameless LNG-IUS. Three typical examples of young women between 16 and 20 years of age, 1Gynecological Outpatient Clinic and IUD Training Center, Ghent, who presented with moderate-to-severe primary dysmenorrhea associated with heavy menstrual Belgium; 2Gynecological Outpatient bleeding, are presented as examples. Following pelvic examination, including vaginal sonography, 3 Clinic, Berlin, Germany; GynMünster, a frameless LNG-IUS, releasing 20 µg of LNG/day, was inserted. The three patients developed Münster, Germany amenorrhea, or scanty menstrual bleeding, and absence of pain complaints within a few months. We conclude that continuous, intrauterine progestogen delivery could be a treatment of choice of this inconvenient condition. In addition, the good experiences with the frameless LNG-IUS in other studies suggests that the frameless design may be preferred over a framed LNG-IUS, as the absence of a frame, resulting in optimal tolerance, is particularly advantageous in these women. Keywords: heavy menstrual bleeding, contraception, FibroPlant, intrauterine system Video abstract Introduction In an epidemiologic study of an adolescent population, Klein and Litt reported a prevalence of dysmenorrhea of 59.7%.1 Of patients reporting pain, 12% described it as severe, 37% as moderate, and 49% as mild. -
Epidemiology of Menstrual Disorders in Developing Countries: a Systematic Review
BJOG: an International Journal of Obstetrics and Gynaecology DOI: 10.1046/j.1471-0528.2003.00012.x January 2004, Vol. 111, pp. 6–16 REVIEW Epidemiology of menstrual disorders in developing countries: a systematic review Introduction Information on the prevalence of menstrual complaints in the past three months was obtained in seven countries In developing countries, priority setting in the health (Table 1). These data permit cross national comparisons sector traditionally focuses on the principal causes of mor- in so far as similar questions with a similar time reference tality. More recently, the Global Burden of Disease approach were asked. However, no definitions were provided and incorporates assessment of morbidity and quality of life in considerable variation in the interpretation of questions identifying priorities. Yet, although investigations in various among individuals and across cultures is likely. developing countries reveal that women are concerned by Approximately a dozen subsequent surveys, including menstrual disorders, little attention is paid to understanding community-based, clinic-based and one national census, or ameliorating women’s menstrual complaints.1 Menstrual include some information on menstrual morbidities6–29 dysfunction, like other aspects of sexual and reproductive (Table 2). A few health surveys of special populations, health, is not included in the Global Burden of Disease such as factory workers in Vietnam17 and medical students estimates2,3 and, even as reproductive health programs in Venezuela,27,28 have also included relevant questions expand their focus to address gynaecologic morbidity, the on menstrual disorders. These surveys vary consider- utility of evaluating and treating menstrual problems is ably in the definition of and reference period for men- not generally considered.