1 Site model of allometric scaling and fractal distribution networks of organs Walton R. Gutierrez* Touro College, 27West 23rd Street, New York, NY 10010 *Electronic address:
[email protected] At the basic geometric level, the distribution networks carrying vital materials in living organisms, and the units such as nephrons and alveoli, form a scaling structure named here the site model. This unified view of the allometry of the kidney and lung of mammals is in good agreement with existing data, and in some instances, improves the predictions of the previous fractal model of the lung. Allometric scaling of surfaces and volumes of relevant organ parts are derived from a few simple propositions about the collective characteristics of the sites. New hypotheses and predictions are formulated, some verified by the data, while others remain to be tested, such as the scaling of the number of capillaries and the site model description of other organs. I. INTRODUCTION Important Note (March, 2004): This article has been circulated in various forms since 2001. The present version was submitted to Physical Review E in October of 2003. After two rounds of reviews, a referee pointed out that aspects of the site model had already been discovered and proposed in a previous article by John Prothero (“Scaling of Organ Subunits in Adult Mammals and Birds: a Model” Comp. Biochem. Physiol. 113A.97-106.1996). Although modifications to this paper would be required, it still contains enough new elements of interest, such as (P3), (P4) and V, to merit circulation. The q-bio section of www.arxiv.org may provide such outlet.