9th Congress of Obstetrical and Gynecological Ultrasonography, 9th-12th October 2014, Belek, Antalya, Turkey Abstracts

increases rate of invasive procedures. When procedures per- Objective: The aim of this study was to determine the rela- formed with indications of NT alone or biochemical test tionship between sonographic cervical length, fetal alone, are taken into account this rate further increases. fibronectin (fFN), phIGFBP-1 (Actim partus test), cytokines Keywords: First trimester screening, amniocentesis, cordo- (IL-6, IL-2R and TNF-alpha) and spontaneous preterm centesis. (SPTB) up to 14 days from sampling. Methods: Patients were recruited in period of 6 months OP-010 from September 2013 untill March 2014 with symptoms or A rare form of ectopic on complaints suggestive of preterm labor Consenting women mesoovarium: case report were treated according to usual hospital protocol, with addi- tion of vaginal swabs taken for fetal fibronectin, phIGFBP- Alev Atis, Ozge Deniz Gunduz, Arzu Kublay, 1(Actim partus test) and cervicovaginal IL6, IL2R and TNF- Tolga Karacan, Ali Gedikbasi alpha. The outcome variable was occurrence of preterm Department of & Gynecology, Kanuni Sultan Suleyman Training delivery within 14 days from the day of hospital admission. & Research Hospital, Istanbul, Turkey Objective: Broad ligament pregnancy also termed as Results: Thirty six patients (62.07%) were delivered within intraligamentous pregnancy is a rare form of ectopic pregnan- 14 days from admission. The fetal fibronectin test is a signif- cy. Incidence is reported as 1 in 300 ectopic . icant predictor of preterm delivery. Patients with a positive fetal fibronectin test have an OR of 6.429 (95%CI 1.991- Case: A 34-year-old, multigravida with 3 previous cesarean 20.758) to deliver prematurely. The patients that gave birth section before presented at 8 weeks with intermittent within 14 days of admission were also statistically more like- suprapubic pain and vaginal . She had undergone ly to have a positive phIGFBP-1 test (p=0.02). All but one three cesarean sections before. An abdominal examination showed free fluid and 3x4 cm left in pregnant women that remained pregnant after 14 days of her . She was hospitalized for follow-up examination admission had a serum level of IL-2R below 500 U/mL and and ‚–hcg level was: 10290, the next day she had the symptoms the difference in concentrations between the two groups is of and a fall in hematocrit level so she was statistically significant (p=0.044). The patients that were taken for with the diagnosis of delivered within 14 days of admission in our study group had under general anestesia. Perop she was found to have a rup- an average cervical length of 18.78±5.8 mm, which is signifi- tured 3x4cm bleeding site from left mesoovarium. It was found cantly lower than the average cervical length (23.87±6.36) of to be an intraligamenter pregnancy,primary abdominal prag- patients that remained pregnant after 14 days (p=0.0028). β nancy. After removal of the lesion, -hcg levels decreased. Our results indicated that the cervical length significantly Hystopathological confirmation was done. correlates with the concentration of IL-6 in the CVF Conclusion: A broad ligament pregnancy is an extremely rare (Spearman’s coefficient R=-0.382, p<0.05), i.e. there is a neg- condition; a rare form of ectopic pregnancy, and one type of ative indirect correlation between the two parameters, which . The diagnosis is seldom established means that increased IL-6 concentrations in the CVF mean before . We suggest the use of clinical and ultrasono- shortening of the and vice-versa. Cervical length also graphic findings for the suspicion of pregnancy in the broad correlated with a positive phIGFBP-1 test i.e. patients with a ligament because of high incidence of mortality in case of delay positive test had an average cervical length of 18.5±4.63 mm, in diagnosis. which is significantly lower than patients with a negative test Keywords: Ectopic, intraligamenter pregnancy. – 23.43±7.39 mm (p=0.003). Conclusion: The studied biochemical markers in our study OP-011 were only moderately successful in the prediction of preterm Sonographic cervical length and biochemical delivery. Further research is required in terms of the evalua- markers in spontaneous (SPTB) tion of cost-benefit of using such test to prevent subsequent up to 14 days from sampling unnecessary interventions in the low-risk group, as well as achieve the benefits from such intervention in the high-risk Marija Hadzi Lega1, Ana Daneva Markova1, Milan Stefanovic2 groups of patients. 1University Clinic of Gynecology and Obstetrics, Skopje, Macedonia; 2University Clinic of Gynecology and Obstetrics, Nis, Serbia Keywords: Preterm labor, cervical length, predictive value.

Volume 22 | Supplement | October 2014 SE5