Preparing for the Future of Artificial Intelligence
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Clustering Longitudinal Clinical Marker Trajectories from Electronic Health Data: Applications to Phenotyping and Endotype Discovery
Proceedings of the Twenty-Ninth AAAI Conference on Artificial Intelligence Clustering Longitudinal Clinical Marker Trajectories from Electronic Health Data: Applications to Phenotyping and Endotype Discovery Peter Schulam Fredrick Wigley Suchi Saria Department of Computer Science Division of Rheumatology Department of Computer Science Johns Hopkins University Johns Hopkins School of Medicine Department of Health Policy & Mgmt. 3400 N. Charles St. 733. N. Broadway Johns Hopkins University Baltimore, MD 21218 Baltimore, MD 21205 3400 N. Charles St. [email protected] [email protected] Baltimore, MD 21218 [email protected] Abstract more thorough retrospective or prospective study to confirm their existence (e.g. Barr et al. 1999). Recently, however, Diseases such as autism, cardiovascular disease, and the au- literature in the medical community has noted the need for toimmune disorders are difficult to treat because of the re- markable degree of variation among affected individuals. more objective methods for discovering subtypes (De Keu- Subtyping research seeks to refine the definition of such com- lenaer and Brutsaert 2009). Growing repositories of health plex, multi-organ diseases by identifying homogeneous pa- data stored in electronic health record (EHR) databases tient subgroups. In this paper, we propose the Probabilis- and patient registries (Blumenthal 2009; Shea and Hripc- tic Subtyping Model (PSM) to identify subgroups based on sak 2010) present an exciting opportunity to identify disease clustering individual clinical severity markers. This task is subtypes in an objective, data-driven manner using tools challenging due to the presence of nuisance variability— from machine learning that can help to tackle the problem variations in measurements that are not due to disease of combing through these massive databases. -
Artificial Intelligence in Health Care: the Hope, the Hype, the Promise, the Peril
Artificial Intelligence in Health Care: The Hope, the Hype, the Promise, the Peril Michael Matheny, Sonoo Thadaney Israni, Mahnoor Ahmed, and Danielle Whicher, Editors WASHINGTON, DC NAM.EDU PREPUBLICATION COPY - Uncorrected Proofs NATIONAL ACADEMY OF MEDICINE • 500 Fifth Street, NW • WASHINGTON, DC 20001 NOTICE: This publication has undergone peer review according to procedures established by the National Academy of Medicine (NAM). Publication by the NAM worthy of public attention, but does not constitute endorsement of conclusions and recommendationssignifies that it is the by productthe NAM. of The a carefully views presented considered in processthis publication and is a contributionare those of individual contributors and do not represent formal consensus positions of the authors’ organizations; the NAM; or the National Academies of Sciences, Engineering, and Medicine. Library of Congress Cataloging-in-Publication Data to Come Copyright 2019 by the National Academy of Sciences. All rights reserved. Printed in the United States of America. Suggested citation: Matheny, M., S. Thadaney Israni, M. Ahmed, and D. Whicher, Editors. 2019. Artificial Intelligence in Health Care: The Hope, the Hype, the Promise, the Peril. NAM Special Publication. Washington, DC: National Academy of Medicine. PREPUBLICATION COPY - Uncorrected Proofs “Knowing is not enough; we must apply. Willing is not enough; we must do.” --GOETHE PREPUBLICATION COPY - Uncorrected Proofs ABOUT THE NATIONAL ACADEMY OF MEDICINE The National Academy of Medicine is one of three Academies constituting the Nation- al Academies of Sciences, Engineering, and Medicine (the National Academies). The Na- tional Academies provide independent, objective analysis and advice to the nation and conduct other activities to solve complex problems and inform public policy decisions. -
Genetics and Other Human Modification Technologies: Sensible International Regulation Or a New Kind of Arms Race?
GENETICS AND OTHER HUMAN MODIFICATION TECHNOLOGIES: SENSIBLE INTERNATIONAL REGULATION OR A NEW KIND OF ARMS RACE? HEARING BEFORE THE SUBCOMMITTEE ON TERRORISM, NONPROLIFERATION, AND TRADE OF THE COMMITTEE ON FOREIGN AFFAIRS HOUSE OF REPRESENTATIVES ONE HUNDRED TENTH CONGRESS SECOND SESSION JUNE 19, 2008 Serial No. 110–201 Printed for the use of the Committee on Foreign Affairs ( Available via the World Wide Web: http://www.foreignaffairs.house.gov/ U.S. GOVERNMENT PRINTING OFFICE 43–068PDF WASHINGTON : 2008 For sale by the Superintendent of Documents, U.S. Government Printing Office Internet: bookstore.gpo.gov Phone: toll free (866) 512–1800; DC area (202) 512–1800 Fax: (202) 512–2104 Mail: Stop IDCC, Washington, DC 20402–0001 COMMITTEE ON FOREIGN AFFAIRS HOWARD L. BERMAN, California, Chairman GARY L. ACKERMAN, New York ILEANA ROS-LEHTINEN, Florida ENI F.H. FALEOMAVAEGA, American CHRISTOPHER H. SMITH, New Jersey Samoa DAN BURTON, Indiana DONALD M. PAYNE, New Jersey ELTON GALLEGLY, California BRAD SHERMAN, California DANA ROHRABACHER, California ROBERT WEXLER, Florida DONALD A. MANZULLO, Illinois ELIOT L. ENGEL, New York EDWARD R. ROYCE, California BILL DELAHUNT, Massachusetts STEVE CHABOT, Ohio GREGORY W. MEEKS, New York THOMAS G. TANCREDO, Colorado DIANE E. WATSON, California RON PAUL, Texas ADAM SMITH, Washington JEFF FLAKE, Arizona RUSS CARNAHAN, Missouri MIKE PENCE, Indiana JOHN S. TANNER, Tennessee JOE WILSON, South Carolina GENE GREEN, Texas JOHN BOOZMAN, Arkansas LYNN C. WOOLSEY, California J. GRESHAM BARRETT, South Carolina SHEILA JACKSON LEE, Texas CONNIE MACK, Florida RUBE´ N HINOJOSA, Texas JEFF FORTENBERRY, Nebraska JOSEPH CROWLEY, New York MICHAEL T. MCCAUL, Texas DAVID WU, Oregon TED POE, Texas BRAD MILLER, North Carolina BOB INGLIS, South Carolina LINDA T. -
Non-Independent Investment Research Disclaimer
CONTENT 03 2020 theme – Engines of Disruption 04 Chips go cold in AI winter 05 Stagflation rewards value over growth 06 ECB folds and hikes rates 07 In energy, green is not the new black 08 South Africa gets electrocuted by ESKOM debt 09 Trump announces America First Tax 10 Sweden breaks bad 11 Dems win clean sweep in 2020 election 12 Hungary leaves the EU 13 Asia launches digital reserve currency 2020 rent at twice the price of owning and maybe even slightly normalise viewed as plain fun, the principles Outrageous Predictions 2020 – a tax on the poor if ever there rates, while governments step into behind the Outrageous Predictions was one, and a driver of inequality. the breach with infrastructure and resonate very strongly with our This risks leaving an entire climate policy-linked spending. clients and the Saxo Group. Not - Engines of Disruption generation without the savings just in terms of what could happen STEEN JAKOBSEN, CHIEF INVESTMENT OFFICER needed to own their own house, The list of Outrageous Predictions to the portfolios and wealth typically the only major asset that this year all play to the theme of allocation, but also as an input to many medium- and lower-income disruption, because our current our respective areas of business, households will ever obtain. Thus paradigm is simply at the end of careers and life in general. Looking into the future is something of a fool’s game, but it remains a Already, there are a number of we are denying the very economic the road. Not because we want it to This is the spirit of Outrageous useful exercise — helping prepare for what lies ahead by considering cracks in the system that show mechanism that made the older end, but simply because extending Predictions: to create the very the full possible range of economic and political outcomes. -
Forecasting Innovation Pathways for New & Emerging
Forecasting Innovation Pathways: The Case of Nano-enhanced Solar Cells Alan L. Porter,i Ying Guo,ii Lu Huang,iii Douglas K. R. Robinsoniv ABSTRACT We have recently devised a 10-step framework to extend research profiling to help identify promising commercialization routes for a target emerging technology. Our approach combines empirical and expert analyses. We herein illustrate this framework for the case of nano-enhanced solar cells. INTRODUCTION Our endeavors should be considered within the context of Future-oriented Technology Analyses (“FTA” – see http://foresight.jrc.ec.europa.eu/). Over the years, FTA tools have expanded from technology forecasting of incrementally advancing technologies (for example, consider Moore‟s Law describing some six decades of continual advances in semi-conductor capabilities). 1 Today, considerable interest is directed toward New & Emerging Science & Technologies (“NESTs”) as increasingly, NESTs are anticipated to provide considerable wealth creation. These forms of technologies tend to be less predictable than incremental innovation processes; they are more dependent on discontinuous advances; and the anticipated (disruptive) impacts on markets and on society are difficult (although not impossible) to foresee. In our endeavor to grapple with this challenging situation, we seek to provide usable intelligence, not only to get a handle of the discontinuous development of NEST‟s, but also on the pertinent contextual forces and factors affecting possible technological innovation. However, technology opportunities analysis2 for NESTs poses notable challenges. Recently, we put forward our approach to Forecasting Innovation Pathways (“FIP”).3 That paper provides conceptual background for our endeavors to combine “Tech Mining” 4 and “Multi-path mapping.” 5 It explores the promise of this approach through its application to two illustrative innovation situations, for nano-biosensors and for deep brain stimulation. -
Astro Teller Speaker Profile
Astro Teller Captain of Moonshots and Google X Laboratories CSA CELEBRITY SPEAKERS Astro Teller is an entrepreneur and scientist, with expertise in the field of intelligent technology. He is currently Captain of Moonshots (CEO) of X, Alphabet's moonshot factory for building magical, audacious ideas that through science and technology can be brought to reality. "A respected scientist and seasoned entrepreneur In detail Languages Astro is also co-founder and a current Director of Cerebellum He presents in English. Capital, Inc, a hedge fund management firm whose investments are continuously designed, executed, and improved by a software Want to know more? system based on techniques from statistical machine learning. He Give us a call or send us an e-mail to find out exactly what he was also the co-founder and CEO of BodyMedia, Inc, a leading could bring to your event. wearable body monitoring company. He has successfully created and grown five companies and holds numerous U.S. patents How to book him? related to his work in hardware and software technology. Astro's Simply phone or e-mail us. work in science, literature, art, and business has appeared in international media from the New York Times to CNN to NPR's All Publications Things Considered. He holds a Bachelor of Science in computer 2006 science from Stanford University. Among These Savage Thoughts What he offers you 1997 Astro Teller oversees the secret projects that could reshape our Exegesis lives in coming decades. As expert on intelligent technology, Astro is uniquely qualified to explain the impact of Artificial Intelligence to corporate and conference audiences. -
Superhuman Enhancements Via Implants: Beyond the Human Mind
philosophies Article Superhuman Enhancements via Implants: Beyond the Human Mind Kevin Warwick Office of the Vice Chancellor, Coventry University, Priory Street, Coventry CV1 5FB, UK; [email protected] Received: 16 June 2020; Accepted: 7 August 2020; Published: 10 August 2020 Abstract: In this article, a practical look is taken at some of the possible enhancements for humans through the use of implants, particularly into the brain or nervous system. Some cognitive enhancements may not turn out to be practically useful, whereas others may turn out to be mere steps on the way to the construction of superhumans. The emphasis here is the focus on enhancements that take such recipients beyond the human norm rather than any implantations employed merely for therapy. This is divided into what we know has already been tried and tested and what remains at this time as more speculative. Five examples from the author’s own experimentation are described. Each case is looked at in detail, from the inside, to give a unique personal experience. The premise is that humans are essentially their brains and that bodies serve as interfaces between brains and the environment. The possibility of building an Interplanetary Creature, having an intelligence and possibly a consciousness of its own, is also considered. Keywords: human–machine interaction; implants; upgrading humans; superhumans; brain–computer interface 1. Introduction The future life of superhumans with fantastic abilities has been extensively investigated in philosophy, literature and film. Despite this, the concept of human enhancement can often be merely directed towards the individual, particularly someone who is deemed to have a disability, the idea being that the enhancement brings that individual back to some sort of human norm. -
Future of Research on Catastrophic and Existential Risk
ORE Open Research Exeter TITLE Working together to face humanity's greatest threats: Introduction to The Future of Research in Catastrophic and Existential Risk AUTHORS Currie, AM; Ó hÉigeartaigh, S JOURNAL Futures DEPOSITED IN ORE 06 February 2019 This version available at http://hdl.handle.net/10871/35764 COPYRIGHT AND REUSE Open Research Exeter makes this work available in accordance with publisher policies. A NOTE ON VERSIONS The version presented here may differ from the published version. If citing, you are advised to consult the published version for pagination, volume/issue and date of publication Working together to face humanity’s greatest threats: Introduction to The Future of Research on Catastrophic and Existential Risk. Adrian Currie & Seán Ó hÉigeartaigh Penultimate Version, forthcoming in Futures Acknowledgements We would like to thank the authors of the papers in the special issue, as well as the referees who provided such constructive and useful feedback. We are grateful to the team at the Centre for the Study of Existential Risk who organized the first Cambridge Conference on Catastrophic Risk where many of the papers collected here were originally presented, and whose multi-disciplinary expertise was invaluable for making this special issue a reality. We’d like to thank Emma Bates, Simon Beard and Haydn Belfield for feedback on drafts. Ted Fuller, Futures’ Editor-in-Chief also provided invaluable guidance throughout. The Conference, and a number of the publications in this issue, were made possible through the support of a grant from the Templeton World Charity Foundation (TWCF); the conference was also supported by a supplementary grant from the Future of Life Institute. -
ARCHITECTS of INTELLIGENCE for Xiaoxiao, Elaine, Colin, and Tristan ARCHITECTS of INTELLIGENCE
MARTIN FORD ARCHITECTS OF INTELLIGENCE For Xiaoxiao, Elaine, Colin, and Tristan ARCHITECTS OF INTELLIGENCE THE TRUTH ABOUT AI FROM THE PEOPLE BUILDING IT MARTIN FORD ARCHITECTS OF INTELLIGENCE Copyright © 2018 Packt Publishing All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, without the prior written permission of the publisher, except in the case of brief quotations embedded in critical articles or reviews. Every effort has been made in the preparation of this book to ensure the accuracy of the information presented. However, the information contained in this book is sold without warranty, either express or implied. Neither the author, nor Packt Publishing or its dealers and distributors, will be held liable for any damages caused or alleged to have been caused directly or indirectly by this book. Packt Publishing has endeavored to provide trademark information about all of the companies and products mentioned in this book by the appropriate use of capitals. However, Packt Publishing cannot guarantee the accuracy of this information. Acquisition Editors: Ben Renow-Clarke Project Editor: Radhika Atitkar Content Development Editor: Alex Sorrentino Proofreader: Safis Editing Presentation Designer: Sandip Tadge Cover Designer: Clare Bowyer Production Editor: Amit Ramadas Marketing Manager: Rajveer Samra Editorial Director: Dominic Shakeshaft First published: November 2018 Production reference: 2201118 Published by Packt Publishing Ltd. Livery Place 35 Livery Street Birmingham B3 2PB, UK ISBN 978-1-78913-151-2 www.packt.com Contents Introduction ........................................................................ 1 A Brief Introduction to the Vocabulary of Artificial Intelligence .......10 How AI Systems Learn ........................................................11 Yoshua Bengio .....................................................................17 Stuart J. -
Future Technologies Conference (FTC) 2017 #FTC2017 November 29-30, 2017, Vancouver, Canada
Future Technologies Conference (FTC) 2017 #FTC2017 November 29-30, 2017, Vancouver, Canada SPONSORS AND PARTNERS CONFERENCE VENUE Pan Pacific Hotel Vancouver Suite 300-999 Canada Place, Vancouver British Columbia V6C 3B5, Canada IEEE VANCOUVER SECTION CONFERENCE AGENDA DAY 1 (29th November) DAY 2 (30th November) 7:30 am – 8:15 am Delegates Check-in 8:00 am Delegates Arrive 8:15 am – 10:30 am Conference Opening (Oceanview Suite) 8:30 am – 10:30 am KEYNOTE TALKS (Oceanview Suite) Mohammad S. Obaidat, Fordham University KEYNOTE TALKS Ann Cavoukian, Ryerson University John Martinis, Google Kevin Leyton-Brown, University of British Columbia Peter Mueller, IBM Research James Hendler, Rensselaer Polytechnic Institute (RPI) 10:30 am – 11:00 am Networking Break (Foyer) 10:30 am – 11:00 am POSTER PRESENTATIONS (Foyer) 11:00 am – 12:30 pm PAPER PRESENTATIONS Session 9 - Intelligent Systems 11:00 am – 12:30 pm PROJECT DEMONSTRATIONS (Oceanview Suite) Session 10 - Technology Trends Session 11 - Electronics 12:30 pm – 1:30 pm Lunch (Cypress Suite) 12:30 pm – 1:30 pm Lunch (Cypress Suite) 1:30 pm – 3:30 pm PAPER PRESENTATIONS 1:30 pm – 3:30 pm PAPER PRESENTATIONS Session 1 - Computing Session 12 - Blockchain Session 2 - Software Engineering Session 13 - Ambient Intelligence Session 3 - Intelligent Systems Session 14 - Healthcare Technologies Session 4 - e-Learning Session 15 - Security and Privacy 3:30 pm – 3:45 pm Networking Break (Foyer) 3:30 pm – 3:45 pm Networking Break (Foyer) 3:45 pm – 5:45 pm PAPER PRESENTATIONS 3:45 pm – 6:00 pm PAPER PRESENTATIONS -
Final Exam Review History of Science 150
Final Exam Review History of Science 150 1. Format of the Exam 90 minutes, on canvas 12:25pm December 18. You are welcome to bring notes to the exam, so you could start by filling out this sheet with notes from lectures and the readings! Like the mid-term, the final exam will have two kinds of questions. 1) Multiple choice questions examining your knowledge of key concepts, terms, historical developments, and contexts 2) Short answer questions in which ask you to draw on things you’ve learned in the course (from lecture, readings, videos) to craft a short argument in a brief essay expressing your informed issue on a historical question 2. Sample Questions Multiple Choice: Mina Rees was involved in (and wrote about) which of the following computing projects? A) Silicon Valley start-ups in the dot-com period B) Charles Babbage’s Difference Engine C) Works Projects Administration Tables Project D) Federal funding for computing research after WWII Short Answer: (Your answers should be between 100-200 words, and keep to specifics (events, machines, developments, people) that demonstrate your knowledge of materials covered from the course) A) What are two historical factors important to the development of Silicon Valley’s technology industry after World War II? B) In what ways did the field of programming change (in terms of its status and workers) between World War II and the late 1960s? 3. Topics to Review: Below, is a list of ideas to review for the final exam, which covers material through the entire course. You should review in particular, lecture notes, O’Mara’s The Code and other course readings provided on Canvas. -
Bulletin of the Center for Children's Books
U ILLINO S UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN PRODUCTION NOTE University of Illinois at Urbana-Champaign Library Large-scale Digitization Project, 2007. University of Illinois Graduate School of Library and Information Science University of Illinois Press ... C 'I Finalist for the 1997 National Book Award TOR SEIDLER Mean Margaret PICTURES BY JON AGEE I ·- II : I SLJ Best Books '97 PW Best Books'97 SALA Booklist * School LibraryJournal SPublishers Weekly *Kirkus Reviews "A wildly funny story of a newly wed woodchuck couple who find a willful, wailing human toddler and take her into their home and into their hearts." -SLJ's Best Books '97 "Tor Seidler writes in the great tradition of Kenneth Grahame, Walter R. Brooks, and E. B. White, creating worlds where friendship matters, animals talk, and little girls who listen- even ones as mean as Margaret-can learn a life-changing lot about loving-kindness." -Booklist Ages 5 up $14.95 TR (0-06-205090-7) Michael di Capua Books * HarperCollins Publishers THE B UL LE T IN OF THE CENTER FOR CHILDREN'S BOOKS February 1998 Vol.51 No. 6 A LOOK INSIDE 189 THE BIG PICTURE Baba Yaga ðe Wise Doll ad. by Hiawyn Oram and illus. by Ruth Brown 190 NEW BOOKS FOR CHILDREN AND YOUNG PEOPLE Reviewed titles include: 192 * Rules ofthe Road by Joan Bauer 199 * Gabriella'sSong by Candace Fleming; illus. by Giselle Potter 208 * The World of William Joyce Scrapbook written and illus. by William Joyce 212 * From Slave Ship to Freedom Road by Julius Lester; illus. by Rod Brown 215 * The Girl Who DreamedOnly Geese and Other Tales of the FarNorth ad.