Azu Etd Mr 2011 0062 Sip1 M.Pdf
Total Page:16
File Type:pdf, Size:1020Kb
The University of Arizona Electronic Theses and Dissertations Reproduction and Distribution Rights Form Name (Last, First, Middle) Degree title (eg BA, BS, BSE, BSB, BFA): Honors area (eg Molecular and Cellular Biology, English, Studio Art): Date thesis submitted to Honors College: Title of Honors thesis: :The University of I hereby grant to the University of Arizona Library the nonexclusive Arizona Library Release worldwide right to reproduce and distribute my dissertation or thesis and abstract (herein, the "licensed materials"), in whole or in part, in any and all media of distribution and in any format in existence now or developed in the future. I represent and warrant to the University of Arizona that the licensed materials are my original work, that I am the sole owner of all rights in and to the licensed materials, and that none of the licensed materials infringe or violate the rights of others. I further represent that I have obtained all necessary rights to permit the University of Arizona Library to reproduce and distribute any nonpublic third party software necessary to access, display, run or print my dissertation or thesis. I acknowledge that University of Arizona Library may elect not to distribute my dissertation or thesis in digital format if, in its reasonable judgment, it believes all such rights have not been secured. Signed:______________________________________________ Date: ______________________________________________ Last updated: Nov 15, 2009 !"#$%$&'($)*+,)& & ! "#$%!#&'&(%!)#*%$%!$'+,-.*%!/'!#&'&(%!(*%*/(+#!/'.!$''&0/)$&'!(*1&()!/'.!/!2-%$'*%%!1,/'! +(*/)*.!)#(&-3#!)#*!4+5-$(*!6*')*(!7&(!8')(*1(*'*-(%#$19!"#*!#&'&(%!(*%*/(+#!/'.! $''&0/)$&'!(*1&()!:/%!.&'*!:$)#!/!%;/,,!)#(**!1*(%&'!/,,!#&'&(%!3(&-1!/'.!)#*!2-%$'*%%! 1,/'!:/%!.&'*!:$)#!/!7&-(!1*(%&'!+(&%%<7-'+)$&'/,!)*/;9!! ! "#*!#&'&(%!(*%*/(+#!/'.!$''&0/)$&'!1(&=*+)!$%!/!(*1&()!&'!#&:!)&!2($'3!*')(*1(*'*-(%#$1! /'.!+-,)-(*!'*:!2-%$'*%%*%!:$)#$'!"-+%&'9!>-(!&1*'!$''&0/)$&'!+#/,,*'3*!1,/'!.*)/$,%!#&:! :$)#!,$;$)*.!(*%&-(+*%!:*!+/'!2($'3!'*:!$.*/!+-,)$0/)$&'!+*')*(!)&!"-+%&'!)&!#*,1!$.*/%! *0&,0*!$')&!1(&7$)/2,*!?'3*,!$'0*%)/2,*!+&;1/'$*%9! ! "#*!2-%$'*%%!1,/'!:/%!+(*/)*.!2@!)#*!A*,&+$%!;/'/3*;*')!)*/;B!:#$+#!$'+,-.*%!C&#'<4/(D! E/')&+DB!F/;-*,!8,,$%B!G$'.%*@!8(,$+DB!/'.!"/@,&(!H*.2*(39!8/+#!)*/;!;*;2*(I%!$'.$0$.-/,! (&,*!+/'!2*!7&-'.!&'!)#*!'*J)!1/3*9!8/+#!)*/;!;*;2*(!#/.!/!%1*+$7$+!(&,*!:$)#$'!)#*!)*/;K! #&:*0*(B!)#*!)*/;!/%!/!:#&,*!1/()$+$1/)*.!$'!)#*!+(*/)$&'!&7!&-(!7$'/,!2-%$'*%%!1,/'9!"#*! A*,&+$%!2-%$'*%%!1,/'!.*%+($2*%!&-(!*,*+)($+!2$+@+,*!0*')-(*!+&'+*1)B!+&;1*)$)$0*! /.0/')/3*%B!+&;1*)$)$&'B!)/(3*)!;/(D*)B!;/(D*)$'3!%)(/)*3$*%B!/'.!7$'/'+*%!'*+*%%/(@!)&! 1(&0*!)#/)!&-(!2-%$'*%%!;&.*,!$%!/+#$*0/2,*9! ! ! !"#$%&'#()"*+$)*#(,& & !"#$%&'$()*)+#,#*-$!#),$./0-#$-"#$%&'$10*0/2$34#*$&**05)-60*$7")88#*+#$')4#/9$!"#$ %&'$()*)+#,#*-$!#),$6*:8;<#2$=)/)$>#);<#-?$@6*<2#A$B/86:C?$)*<$>/6--)*A$1;8-2-/0,9$!"#$ 4)4#/$.)2$<656<#<$6*-0$2#:-60*2$)*<$6*<656<;)8$+/0;4$,#,D#/2$./0-#$#):"$2#:-60*$-")-$.)2$ -"#*$#<6-#<$DA$#5#/A$+/0;4$,#,D#/9$=)/)$E0:;2#<$0*$-"#$)<,62260*2$4/0:#22$)*<$-"#$ -6,#86*#$0E$6,48#,#*-)-60*9$@6*<2#A$E0:;2#<$0*$;*<#/2-)*<6*+$)*<$6<#*-6EA6*+$-"#$C#A$ 4)/-6:64)*-2$)*<$-"#$0440/-;*6-A$E0/$-"#,9$>/6--)*A$E0:;2#<$0*$-"#$6*F<#4-"$:0*2;,#/$ /#2#)/:"$)*<$-"#$:0,4#-6-0/$)*)8A2629$$ $ &*$)<<6-60*$-0$-"#$10*0/2$34#*$&**05)-60*$7")88#*+#$4)4#/?$-"/0;+"$-"#$"0*0/2$ B*-/#4/#*#;/2"64$4/0+/),$&$")<$:8)22#2$.6-"$-"#$(>G$B*-/#4/#*#;/2"64$2-;<#*-29$!"62$ #H4#/6#*:#$)880.#<$,#$-0$#*+)+#$6*$)$"6+"#/$8#5#8$0E$-"6*C6*+$)*<$)*)8A262$-"/0;+"0;-$-"#$ 4/0+/),9$ $ $ !"#$I#80:62$,)*)+#,#*-$-#),$./0-#$-"#$I#80:62$D;26*#22$48)*9$!"#$,)*)+#,#*-$-#),$ 6*:8;<#2$J0"*F()/C$>)*-0:C?$K),;#8$B8862?$@6*<2#A$B/86:C?$)*<$!)A80/$1#<D#/+9$!"#$ D;26*#22$48)*$.)2$6*6-6)88A$2486-$;4$DA$24#:6)86L)-60*M$"0.#5#/?$#5#/A$,#,D#/$")2$#<6-#<?$ :/6-6N;#<?$)*<$)8-#/#<$#):"$2#:-60*9$!"#$6*<656<;)88A$./6--#*$2#:-60*2$.#/#$/#562#<$,)*A$ -6,#2$DA$-"#$#*-6/#$+/0;4$)*<$+/0;4$6*E0/,)-60*$.)2$)<<#<$-0$#):"$6*<656<;)8$2#:-60*9$ B):"$6*<656<;)8$,#,D#/O2$E0:;2$62$D#80.9$ $ -#.(/01"2&31()#42&/&J0"*F()/C$62$-"#$P#*#/)8$Q6/#:-0/$0E$I#80:62?$"#$62$4/6,)/68A$ /#240*26D8#$E0/$4/0<;:-$/#2#)/:"$6*$)<<6-60*$-0$#2-)D862"6*+$)*<$,)6*-)6*6*+$/#8)-60*2"642$ .6-"$2;4486#/2?$<62-/6D;-0/2?$)*<$/#-)68#/29$J0"*F()/C$E0:;2#<$0*$-"#$E#)26D686-A$0E$0;/$ 4/0<;:-$<#26+*$)*<$-"#$-#2-6*+$0E$0;/$4/0-0-A4#9$$ $ 516$78&988*,&:&K),$62$-"#$R6*)*:#$Q6/#:-0/$0E$I#80:62?$"#$62$4/6,)/68A$/#240*26D8#$E0/$-"#$ E6*)*:6)8$4/0S#:-60*2?$:)8:;8)-60*$0E$04#/)-6*+$#H4#*2#2?$)*<$<#5#804,#*-$0E$6*5#2-0/$ 4/0402)82$E0/$2-)/-F;4$E;*<6*+$/0;*<29$K),$E0:;2#<$0*$"0.$-0$,)6*-)6*$:02-2$-0$/#)86L#$ 4/0E6-$)*<$/#):"$)$TUH$V3&$E0/$6*5#2-0/2$6*$E65#$A#)/29$ $ ;*(<,7=&9"8*42&:&@6*<2#A$62$-"#$()/C#-6*+$Q6/#:-0/$0E$I#80:62?$2"#$62$4/6,)/68A$/#240*26D8#$ E0/$6<#*-6EA6*+$-)/+#-$,)/C#-2?$-)680/6*+$:0,,;*6:)-60*2$-0$-)/+#-$:;2-0,#/2?$:/#)-6*+$)*$ 6*-#+/)-#<$,)/C#-6*+$:0,,;*6:)-60*2$48)*?$)*<$6*-#+/)-6*+$2)8#2$)*<$2;440/-$2-/)-#+6#29$ @6*<2#A$E0:;2#<$0*$/#2#)/:"6*+$-"#$<#,0+/)4"6:2$)*<$42A:"0+/)4"6:2$0E$0;/$-)/+#-$,)/C#-$ W/#-)68#/2$)*<$#*<F;2#/2X$-0$#EE#:-65#8A$:0,,;*6:)-#$0;/$5)8;#$4/04026-60*$-0$-"#2#$+/0;429$ $ >1=8#"&?7<+7"@&:&!)A80/$62$-"#$34#/)-60*2$Q6/#:-0/$0E$I#80:62?$"#$62$4/6,)/68A$/#240*26D8#$ E0/$-"#$2;448AF:")6*$04#/)-60*2$)*<$-#:"*080+A$)24#:-2$-")-$2;//0;*<$-"#$<#5#804,#*-$0E$ 0;/$6*-#+/)-#<$.#D26-#$-")-$0EE#/2$)$:;2-0,6L)D8#$D6C#$-0089$!)A80/$)820$,)*)+#2$)88$ #*-#/4/62#$,)*)+#,#*-$-0082$6*:8;<6*+$:;2-0,#/$6*E0/,)-60*$)*<$2;4486#/$<)-)D)2#$ 20E-.)/#9$$ !"#$#%&'%()$ *&+&%,$-./+$"++&0(12&+$34(55/+'/$ 6(%($7/(89/1$ :2+9,/;$<%52=>$ 7%211(+;$*851,1%&)! ! !"#$%&'(#)%"*#%*+%&,-* 1'.23!3.(24!),&56(%76!&8!956*%.66.6!8&2:!(%7!()).:;)!)&!6..<!(%/.-!*%'.6):.%)=!>5)! &8!),.6.!956*%.66.64!&%-3!%*%.!;.2?.%)!(2.!*%'*).7!)&!;2.6.%)!)&!*%'.6)&26=!@2&:!),*6!6:(--! /2&5;4!),2..!;.2?.%)!&8!956*%.66!6)(2)5;6!(?)5(--3!2.?.*'.!*%'.6):.%)=!>%-3!A=B!;.2?.%)! 2.?.*'.!),.!6)(%7(27!8*'.!)*:.6!2.)52%!&%!),.*2!*%'.6):.%)=!C,2&5/,!),.!"#$!$2&/2(:! D"&2<!#%!$2&/2.66!$2&/2(:E4!6)(2)5;6!F*--!9.!9.)).2!;&6*)*&%.7!)&!;2.6.%)!)&!*%'.6)&26!(%7! 2.?.*'.!),.!*%'.6):.%)!),()!),.3!2.G5*2.=! !&,.-*/.$#)()0."#1** C,.!;2*:(23!/&(-!&8!&52!956*%.66!7.'.-&;:.%)!:&7.-!*6!)&!-*%<!)&/.),.2!7*88.2.%)! /2&5;6!*%'&-'.7!*%!),.!.%)2.;2.%.52*(-!;2&?.66=!!C,.!8&--&F*%/4!&5)-*%.6!),.!7*88.2.%)! ;-(3.26!),()!F*--!9.!*%'&-'.7!*%!),.!"#$!$2&/2(:=!!C,.2.!(2.!),2..!7*88.2.%)!/2&5;6!&8! ;.&;-.!F,&!?&5-7!;&).%)*(--3!9.!*%'&-'.7H!!*%%&'()&264!*7.(!;2&'*7.264!(%7!:.%)&26=!!! 2"#$,0$,",'$1* C,.!.%)2.;2.%.526!(2.!;(2)*?*;(%)6!*%!),.!;2&/2(:!F,&!F&5-7!-*<.!)&!25%!),.*2!&F%! 956*%.66=!!C,.3!?&5-7!92*%/!(!'.%)52.!*7.(!),.3!F&5-7!-*<.!)&!;5265.!&2!?,&&6.!(%!*7.(!82&:! ),.!#7.(!I(%<=!!J&6)!;.&;-.!(2.!:&2.!F*--*%/!)&!6)(2)!),.*2!&F%!956*%.66!F,.%!),.3!,('.! ),.!.%.2/3!(%7!&;;&2)5%*)3K!),.2.8&2.4!2.?.%)!?&--./.!/2(75().6!F&5-7!9.!),.!*7.(-! ?(%7*7().6!8&2!.%)2.;2.%.526=!!C,.6.!;.&;-.!F&5-7!9.!*%!),.!LMNOP!(/.!2(%/.4!F,*?,!8(--6!*%! ),.!&-7.2!:*--.%%*(-!?()./&23=!!! !! I3!)(2/.)*%/!(!3&5%/.2!7.:&/2(;,*?4!&52!956*%.66!:&7.-!F&5-7!;2&'*7.!),.6.! 3&5%/!.%)2.;2.%.526!F*),!6<*--!7.'.-&;:.%)!),2&5/,!&;)*&%(-!F&2<6,&;6!(%7!.Q;.2*.%?.7! :.%)&26=!#%!(77*)*&%4!(--&F*%/!),.:!)&!;(2)*?*;().!F*),&5)!(%!.Q;-*?*)!*7.(!F*--!72(F!:&2.! ;(2)*?*;(%)6!)&!&52!;2&/2(:=!!! !"#$!#%%&'()*&%!+,(--.%/.!0! C,.!"#$!$2&/2(:!(--&F6!8&2!),.!&;;&2)5%*)3!8&2!(!;(2)%.26,*;!F*),!),.!J?R5*2.! 1%)2.;2.%.526,*;!$2&/2(:=!!",*-.!:&6)!6)57.%)6!*%!J?R5*2.!:(3!%&)!F(%)!)&!?&%)*%5.! F*),!),.*2!'.%)52.!*7.(4!:(%3!F&5-7!-*<.!)&!?&%)*%5.!),.*2!*%'&-'.:.%)!*%! .%)2.;2.%.526,*;=!>52!?.%).2!F*--!;2&'*7.!J?R5*2.!6)57.%)6!F*),!(!6*:;-.2!)2(%6*)*&%!*%)&! ?2.()*%/!(!%.F!*7.(!(%7!8&2:*%/!(!%.F!).(:4!F,*?,!F*--!*%?2.(6.!),.*2!?,(%?.6!8&2!65??.66=!! S-),&5/,!F.!(2.!&;.%*%/!),.!"#$!$2&/2(:!)&!J?R5*2.!6)57.%)64!(%3&%.!82&:!),.! ?&::5%*)3!:(3!(;;-3=! !""%3.#%$1* #%!(77*)*&%!)&!),.!.%)2.;2.%.5264!),.2.!F*--!9.!(%&),.2!/2&5;!&8!;(2)*?*;(%)6H!),.! *%%&'()&26=!C,*6!/2&5;!F*--!?&%6*6)!&8!:.:9.26!&8!),.!C5?6&%!?&::5%*)3!F,&!,('.!(%!*7.(! 8&2!(!956*%.664!95)!7&!%&)!,('.!),.!)*:.!&2!),.!:.(%6!)&!-(5%?,!(!%.F!'.%)52.=!C,.! *%%&'()&26!F*--!659:*)!),.*2!*7.(!)&!),.!"#$!#7.(!I(%<!8&2!?&%6*7.2()*&%!93!),.! .%)2.;2.%.526!(%7!),.!"#$!I&(27=!#8!(%!.%)2.;2.%.52!?,&&6.6!),.*2!*7.(4!),.!*%%&'()&2!F*--! 2.?.*'.!2&3(-)*.6!*%!),.!85)52.!956*%.664!F,*?,!F*--!9.!%./&)*().7!9(6.7!&%!),.!*7.(! 7.'.-&;:.%)!6)(/.=!! +,"#%$1* C,.!8*%(-!/2&5;!&8!;(2)*?*;(%)6!*%!),.!"#$!$2&/2(:!*6!:.%)&26=!C,*6!/2&5;!F*--! ;2&'*7.!.Q;.2*.%?.!(%7!<%&F-.7/.!)&!),.!.%)2.;2.%.526=!I.?(56.!),.!:(T&2*)3!&8!),.! .%)2.;2.%.526!F*--!9.!2.-()*'.-3!3&5%/!(%7!%.F!)&!),.!956*%.66!F&2-74!),.3!F*--!*%.'*)(9-3! ,('.!/(;6!*%!),.*2!<%&F-.7/.=!!J.%)&26!(2.!.Q;.2)6!*%!),.*2!8*.-7!F,&!(2.!F*--*%/!)&!7&%().! ),.*2!)*:.!(%7!<%&F-.7/.!*%!.Q?,(%/.!8&2!.G5*)3!*%!(%!.(2-3N6)(/.!'.%)52.=!!!C,.!:.%)&26! F*--!,('.!.Q;.2)*6.!*%!),.!8&--&F*%/!(2.(6H!:(2<.)*%/4!(??&5%)*%/4!/2(;,*?!7.6*/%4!2.6.(2?,! (%7!7.'.-&;:.%)4!).?,%&-&/34!8*%(%?.4!*%).--.?)5(-!;2&;.2)34!?&::5%*?()*&%4!(%7!85%7*%/=!!! !"#$!#%%&'()*&%!+,(--.%/.!L! 4'1)",11*+%&,-** 500%$#'")#6*7%$*8#.$#'01* C,.!"#$!$2&/2(:!?2.().6!'(6)!&;;&2)5%*)*.6!8&2!-&?(-!6)(2)5;6!*%!),.!C5?6&%! ?&::5%*)3=!"*),!(!:.:9.26,*;!8..!&8!&%-3!ULAA4!9577*%/!.%)2.;2.%.526!?(%!-.(2%!,&F!)&! .88.?)*'.-3!-(5%?,!(!956*%.66!F*),!.*),.2!),.*2!*7.(!&2!(%!*7.(!82&:!&52!"#$!#7.(!I(%<=! V.?.%)!/2(75().6!(%7!?&::5%*)3!:.:9.26!F,&!(2.!.%),56*(6)*?!(%7!:&)*'().7!)&!-(5%?,!(! 956*%.66!(2.!?&(?,.7!&%!,&F!)&!65??.6685--3!/(*%!*%'.6):.%)!(%7!-(5%?,!),.*2!'.%)52.=!! #%*)*(--34!F.!F*--!&%-3!(--&F!0M!/2&5;6!)&!;(2)*?*;().!*%!),.!;2&/2(:!;.2!0ANF..<!).2:=!