Michael Stuart Schaffer, Md

MICHAEL STUART SCHAFFER, MD CURRICULUM VITAE

I. BIOGRAPHICAL DATA

Date and Place of Birth March 12, 1950, Alexandria, Minnesota, United States of America

Marital Status Married, Lynda R. Schaffer (September 6, 1981) Two Daughters, Sara Marlane (June 5, 1983) Claire Allison (October 4, 1985)

Social Security 475-50-2153

II EDUCATION AND TRAINING

HIGHLAND PARK JR. AND SR. HIGH SCHOOL ST. PAUL, MINNESOTA

UNIVERSITY OF MINNESOTA MINNEAPOLIS, MINNESOTA Degree: B.A. (Physiology) JUNE, 1972

UNIVERSITY OF MINNESOTA SCHOOL OF MEDICINE MINNEAPOLIS, MINNESOTA Degree: M.D. JUNE, 1976

UNIVERSITY OF COLORADO SCHOOL OF MEDICINE DENVER, COLORADO PEDIATRIC INTERN 1976-1977

UNIVERSITY OF COLORADO SCHOOL OF MEDICINE DENVER, COLORADO PEDIATRIC RESIDENT 1977-1979

THE HOSPITAL FOR SICK CHILDREN TORONTO, ONTARIO, CANADA PEDIATRIC CARDIOLOGY FELLOW 1979-1981

THE HOSPITAL FOR SICK CHILDREN TORONTO,ONTARIO,CANADA PEDIATRIC CARDIOLOGY RESEARCH FELLOW (NUCLEAR CARDIOLOGY) 1981-1982

UNIVERSITY OF COLORADO HEALTH SCIENCES CENTER CLINICAL ELECTROPHYSIOLOGY DENVER, COLORADO JULY 1987 - DECEMBER 1987

1 MEDICAL UNIVERSITY OF SOUTH CAROLINA PEDIATRIC ELECTROPHYSIOLOGY CHARLESTON, SOUTH CAROLINA MARCH 1989 - JUNE 1989

RADIOFREQUENCY CATHETER ABLATION OF CARDIAC ARRHYTHMIAS NORTH AMERICAN SOCIETY OF PACING AND ELECTROPHYSIOLOGY (NASPE) WASHINGTON, DC JUNE 1, 1991

III. BOARD CERTIFICATION

AMERICAN BOARD OF PEDIATRICS JUNE 15, 1980 #24631

AMERICAN BOARD OF PEDIATRICS SUB-BOARD OF PEDIATRIC CARDIOLOGY OCTOBER 21, 1983 #680

IV. LICENSURE

MISSOURI: R5C67 (exp. date 1-31-85) COLORADO: 21268 MONTANA: 5106 (exp. date 3-31-99) WYOMING: 3670A

V. ACADEMIC APPOINTMENTS

ASSISTANT PROFESSOR OF PEDIATRICS DEPARTMENT OF PEDIATRICS ST. LOUIS UNIVERSITY SCHOOL OF MEDICINE ST. LOUIS, MISSOURI JUNE 1982 - JUNE 1984

ASSISTANT PROFESSOR OF PEDIATRICS DEPARTMENT OF PEDIATRICS SECTION OF CARDIOLOGY UNIVERSITY OF COLORADO SCHOOL OF MEDICINE DENVER, COLORADO JULY 1984 - JUNE 1990

ASSOCIATE PROFESSOR OF PEDIATRICS DEPARTMENT OF PEDIATRICS SECTION OF CARDIOLOGY UNIVERSITY OF COLORADO SCHOOL OF MEDICINE DENVER, COLORADO JULY, 1990 – JUNE, 2000

PROFESSOR OF PEDIATRICS DEPARTMENT OF PEDIATRICS SECTION OF CARDIOLOGY UNIVERSITY OF COLORADO SCHOOL OF MEDICINE DENVER, COLORADO JULY 1, 2000 – PRESENT 2 PROFESSOR OF MEDICINE DEPARTMENT OF MEDICINE DIVISION OF MEDICINE UNIVERSITY OF COLORADO SCHOOL OF MEDICINE DENVER, COLORADO JULY 1, 2002 – JUNE 30, 2003

VI. DIRECTORSHIPS

DIRECTOR, PEDIATRIC CARDIAC CATHETERIZATION LABORATORY CARDINAL GLENNON MEMORIAL HOSPITAL FOR CHILDREN ST. LOUIS, MISSOURI JANUARY 1983 - MARCH 1984

DIRECTOR, PEDIATRIC CARDIAC CATHETERIZATION LABORATORY UNIVERSITY OF COLORADO HEALTH SCIENCES CENTER DENVER, COLORADO JULY 1984 - JUNE 1990

DIRECTOR, PEDIATRIC CARDIOLOGY FELLOWSHIP PROGRAM UNIVERSITY OF COLORADO HEALTH SCIENCES CENTER DENVER, COLORADO JULY 1985 - JUNE 1986

DIRECTOR OF EDUCATION PEDIATRIC CARDIOLOGY UNIVERSITY OF COLORADO HEALTH SCIENCES CENTER/ THE CHILDREN'S HOSPITAL DENVER, COLORADO JULY 1985 - PRESENT

MEDICAL STUDENT PEDIATRIC CARDIOLOGY ELECTIVE #8004 UNIVERSITY OF COLORADO SCHOOL OF MEDICINE JULY 1985-PRESENT

3RD YEAR MEDICAL STUDENT CORE LECTURE SERIES "PEDIATRIC CARDIOLOGY" UNIVERSITY OF COLORADO SCHOOL OF MEDICINE

DIRECTOR, ELECTROPHYSIOLOGY LABORATORY THE CHILDREN'S HOSPITAL DENVER, COLORADO APRIL 1990 - 2007

DIRECTOR, CARDIAC ARRHYTHMIA CENTER THE CHILDREN'S HOSPITAL DENVER, COLORADO SEPTEMBER 1991 -2008

CHAIRMAN, CREDENTIALS COMMITTEE UNIVERSITY OF COLORADO HEALTH SCIENCES CENTER DENVER, COLORADO APRIL 1988 - APRIL 1994

CHAIRMAN, QUALITY ASSURANCE COMMITTEE PEDIATRIC CARDIOLOGY 3 THE CHILDREN'S HOSPITAL DENVER, COLORADO APRIL 1991 – 2010

CLINIC MEDICAL DIRECTOR CARDIOLOGY THE CHILDRENS HOSPITAL DECEMBER 2007-PRESENT

VII. HOSPITAL STAFF APPOINTMENTS

CARDINAL GLENNON MEMORIAL HOSPITAL FOR CHILDREN DEPARTMENT OF PEDIATRICS ST. LOUIS, MISSOURI JULY 1982

UNIVERSITY OF COLORADO HEALTH SCIENCES CENTER DEPARTMENT OF PEDIATRICS/SECTION OF CARDIOLOGY DENVER, COLORADO APRIL 1984

THE CHILDREN'S HOSPITAL DEPARTMENT OF CARDIOLOGY DENVER, COLORADO NOVEMBER 1984

DENVER HEALTH AND HOSPITALS DENVER GENERAL HOSPITAL DEPARTMENT OF PEDIATRICS DENVER, COLORADO NOVEMBER 1984

ROSE MEDICAL CENTER DEPARTMENT OF PEDIATRICS DENVER, COLORADO NOVEMBER 1984

NATIONAL JEWISH CENTER FOR IMMUNOLOGY AND RESPIRATORY MEDICINE DEPARTMENT OF PEDIATRICS DENVER, COLORADO NOVEMBER 1988

ST. JOSEPH'S HOSPITAL DEPARTMENT OF PEDIATRICS DENVER, COLORADO JUNE 1990

PRESBYTERIAN/ST. LUKE'S HEALTH CARE SYSTEM DEPARTMENT OF PEDIATRICS DENVER, COLORADO JUNE 1991

THE CHILDRENS HOSPITAL DEPARTMENT OF PEDIATRICS 13123 E. 16TH AVE. AURORA, COLORADO 80045

VIII. MEDICAL SOCIETIES

4 AMERICAN COLLEGE OF CARDIOLOGY, FELLOW

AMERICAN ACADEMY OF PEDIATRICS, FELLOW SECTION OF CARDIOLOGY

AMERICAN HEART ASSOCIATION COUNCIL ON CARDIOVASCULAR DISEASE IN THE YOUNG

PEDIATRIC ELECTROPHYSIOLOGY SOCIETY

WESTERN SOCIETY FOR PEDIATRIC RESEARCH

NORTH AMERICAN SOCIETY FOR PACING AND ELECTROPHYSIOLOGY

PEDIATRIC ELECTROPHYSIOLOGY RADIOFREQUENCY ABLATION REGISTRY

COLORADO ELECTROPHYSIOLOGY GROUP

IX. SPECIAL AREAS OF INTEREST AND RESEARCH

Electrophysiology 1) Clinical a. Transesophageal EPS in neonates with SVT b. Autonomic/Tilt table testing c. Pacemaker implantation and follow up d. Radiofrquency catheter ablation 1. Complications e. Cardiac transplant related arrhythmia

2). Research a. Fetal, developmental electrophysiology and electropharmacology b. Long QT syndrome/sudden infant death syndrome c. Neonatal SVT, risk of late recurrence d. Volume loading vs. beta-blockade in the treatment of syncope e. Retrospective and prospective evaluation of epicardial pacemaker leads f. Propafol: Vascular and electrophysiologic effects in children g. Halothane: Arrythmogenicity during induction h. Desflurane: Electrophysiologic effects in children i. Cocaine: arrhythmias following intrauterine exposure

Pediatric Nuclear Cardiology 1). Right ventricular function 2). Right ventricular response to exercise 3). Phase Analysis

Pulmonary Hypertension and Myocardial Development in Bronchopulmonary Dysplasia

STUDENT RESEARCH SUPERVISION

Early Identification of Coarctation of the Aorta in Infants A Pilot Study. Robert E. Ledwith, Child Health Associate Program, University of Colorado Health Sciences Center (Paper presented March 28, 1989)

The Long QT Interval during Exercise Ms.Allison Sennett: Fitness and Exericse Kinesiology Internship Project University of Northern Colorado 5 June,1992-September,1992

Junctional Ectopic Tachycardia, Diagnosis and Managhement Ms. Joan Sheetz, MS IV, University of Colorado Medical School, Nov-Dec, 1994. presented at Team Approach to Pediatric Cardiovasscular Medicine, Vail, Colorado,February 28, 1995

Cardiac function in Children with Congenital Complete Heart Block Mr. Eric Ridout, MS IV University of Colorado Medical School June-Sept, 1995

Electrophysiologic effects of desflurane anesthesia in pediatric patients, Dr. Andrew Snyder, (PL-2) University of Colorado Medical School 1995-1997

Arrhythmias following intrauterine cocaine exposure, Dr. David Gremmels, (PL-2) University of Colorado Medical School 1996-1997

X. FUNDING

Pediatric Cardiology Fellowship training grant, Telectronics Corp, 1996 $120.000.00

D,L Sotalol pharmicokinetics/pharmicodynamics in pediatric patients Berlex, 1999 $85,000.00

Prospective Assessment After Pediatric Cardiac Ablation (PAPCA) NLHBI 1999 (RO1-HL58620-01A1), co investigator $28,500

11. VISITING PROFESSORSHIPS/AWARDS

III. Annual Turkish Pediatric Cardiology and Cardiac Surgery Congress and Hacettepe Hospital, Ankara, Turkey, May 3-6 and May 7, 2001.

Pacemaker Award American Heart Association/Rocky Mountain Affiliate 2006

Ain Shams Hospital, Cairo Egypt, October 11-12, 2007

Outstand Service Award The Children’s Hospital January, 2008

Career Teaching Scholars Award Department of Pediatrics University of Colorado, Denver, School of Medicine December, 2010

Gary Way Award (resident teaching) 6 Department of Pediatrics University of CO School of Medicine June, 2012

12. PUBLICATIONS

1. Schaffer MS, Zuberbuhler P, Wilson G, Rose V, Duncan W, Rowe RD. Cardiomyopathy - An unusual presentation of pheochromocytoma in children. J Pediatr, 99:276, 1981.

2. Duncan WJ, Fowler RS, Schaffer MS, Rowe RD. Serial two dimensional echocardiographic studies suggesting disappearance of mural thrombi after treatment with anticoagulants in children - a report of two cases. Cardiovasc Ultrasonography 1: 179-183, 1982.

3. Freedom RM, Schaffer MS, Culham JAG, Rowe RD. Anomalous low insertion of the right superior vena cava. Br Heart J 48: 601- 603, 1982.

4. Schaffer MS, Freedom RM, Rowe RD. Hypertrophic cardiomyopathy presenting before two years of age in 13 patients. Pediatr Cardiol, April- June 4 (2): 113-119, 1983.

5. deSouza ME, Schaffer MS, Gilday DL, Rose V. Exercise radionuclide angiography in hyperlipidaemic children with apparently normal hearts. Nuc Med Comm 5:13-17, 1984.

6. Schaffer MS, Nouri S. Waggoner A, deMello D, Pennington DG. Infantile cardiac fibromatosis: correlation of antemortem necropsy findings. Texas Heart Institute Journal 110: 90-95, 1984.

7. Schaffer MS, deSouza M, Olley PM, Rowe RD, Gilday DL. Qualitative phase analysis in pediatric nuclear cardiology. Pediatr Cardiol 5:179-198,1984.

8. Schaffer MS, Nouri S, Chen S, et al. Fatal aortic rupture presenting as chest pain in an adolescent-the role of echocardiography in occult cystic medial necrosis. Clin Pediatr 24:216- 218, 1984.

9. Waggoner AD, Nouri S, Schaffer MS, Chen S. Echocardiographic evaluation of left ventricular function, mass and wall stress in children with isolated ventricular septal defect. Texas Heart Institute Journal 12: 163-170, 1985.

10. Schaffer MS, Fowler RS, Corey P, Steele C, Rigby ML, Rowe RD. Electrocardiographic estimate of peak systolic pressure gradient with aortic stenosis. J Electrocardiology 18 (3):203-210, 1985.

11. Schaffer MS, Samuels L, Nouri S. Equilibrium radionuclide ventriculography in single ventricle. Clin Nuc Med 10:669, 1985.

12. Loehr JP, Schaffer MS, Cowgill LD, Clarke DR, Campbell DN. Aortoventriculoplasty in a five month old infant. An alternative approach to the treatment of critical aortic stenosis of infancy. Pediatr Cardiol 6:323-325, 1986.

13. Schaffer MS, Langendorfer SI, Campbell DN. AIDS related complex following infant cardiac surgery. Pediatr Cardiol 6: 335-336, 1986.

14. Schaffer MS, Campbell DN, Clarke RD, Wiggins JW, Wolfe RR. Aortoventriculoplasty in children. J of Thorac Cardiovasc Surg 92: 391-395, 1986.

15. Schaffer MS, Clarke DR, Campbell DN, Madigan CK, Wiggins JW, Wolfe RR. The St. Jude Medical Cardiac Valve in Infants and Children: The role of anticoagulation therapy. J Am Coll of Cardiol 9:235-239, 1987.

16. Abman SH, Schaffer MS, Wiggins JW. Washington RL, Manco-Johnson M, Wolfe RR. 7 Pulmonary Vascular Extraction of Circulating Norepinephrine in Infants with Bronchopulmonary Dysplasia. Pediatr Pulmonol 3: 386-391, 1987.

17. Schaffer MS, deSouza M, Gilday DL, Rose V. Exercise Radionuclide Right Ventriculography in Children. Pediatr Cardiol 8: 235-240, 1987.

18. Abman SH, Burchell MF, Schaffer MS, Rosenberg AA. Late Sudden Unexpected Deaths in Hospitalized Infants with Bronchopulmonary Dysplasia. AJDC 143: 815-819, 1989.

19. Wolfe RR, Loehr JP, Schaffer MS, Wiggins JW. Hemodynamic Effects of Ketamine, Hypoxia and Hyperoxia in Children Residing above 1200 Meters. Am J Cardiol 67: 84-87, 1990.

20. Schaffer MS, Tripple DL, Buckles DS, Young RH, Dolan PL, Gillette PC. The Longitudinal Time Course of QTc in Early Infancy Preliminary results of a prospective sudden infant death syndrome surveillance program. J Perinatol XI: 57-62, 1991.

21. Schaffer MS, Gillette PC. Ventriculoatrial Intervals During Narrow Complex Reentrant Tachycardia in Children. Am Heart J 121: 1699-1702, 1991.

22. Schroeder JK, Albert J, Clarke DR, Schaffer MS, Wolfe RR, Hays T. Hemolysis due to branch pulmonary stenosis after the arterial switch procedure. Ann Thorac Surg. 51: 491-492, 1991.

23. Allen SW, Chatfield BA, Koppenhafer SL, Schaffer MS, Wiggins JW, Wolfe RR, Abman SJ. Circulating Immunoreactive Endothelin-1 in Children with Pulmonary Hypertension Associated with Acute Hypoxic Pulmonary Vasoreactivity. Am Rev Resp Dis 148: 519-522; 1993.

24. Case CL, Schaffer MS, Dhala AA, Gillette PC, Fletcher SE. Radiofrequency Ablation of an Accessory Connection in a Fontan Patient. PACE, Vol 16:1434-1436, 1993.

25. Silka MJ, Kron J, Dunnigan A, Dick M,II, for the Pediatric Electrophysiology Society. Sudden Cardiac Death and the Use of Implantable Cardioverter Defibrillator in Pediatric Patients. Circulation 87: 800-807, 1993.

26. Abman SH, Kinsella JP, Schaffer MS, Wilkening RB. Inhaled Nitric Oxide in the Management of a Premature Newborn with Severe Respiratory Distress and Pulmonary Hypertension. Pediatrics 92: 606-609, 1993.

27. Ivy DD, Loehr JP, Schaffer MS. Usefulness of Prolonged Prostaglandin Infusion in Neonates with Severe Ebstein's Anomaly. Am J Cardiol 72: 1327-1329, 1993.

28. Kugler JD, Danford DA, Deal B, Friedman R, Gillette PC, Silka MJ, VanHare GF, Walsh E, and the other participating members of the Pediatric Electrophysiology Society. Radiofrequency Catheter Ablation in Children and Adolescents: Early Results in 653 Patients from 24 Centers. N Eng J Med 330: 1481-1487, 1994.

29. Danford DA, Kugler JD, Deal B, Case C, Friedman R, Saul JP, Silka M, Van Hare G and participating members of the Pediatric Electrophysiology Society. The Learning Curve for Radiofrequency Ablation of Tachyarrhythmias in Pediatric Patients. Am J Cardiol 75:587-590, 1995.

30. Morrison JE, Schaffer MS. Cardiac Arrhythmias during Laryngoscopy and Intubation. Can J Anaesthesia 42:748-749, 1995

31. Scott WA, Pongiglione G, Bromberg BI, Schaffer MS, Deal BJ, Fish FA,Dick M. Randomized Comparison of Atenolol and Fludrocortisone Acetate in the Treatment of Pediatric Neurally Mediated Syncope. Am J Cardiol 76:400-402, 1995.

32. Schaffer MS, Silka MJ, Ross BA, Kugler JD and participating members of the Pediatric Electrophysiology Society. Inadvertent Atrioventricular Block During Radiofrequency Catheter Ablation: Results of the Pediatric Radiofrequency Ablation Registry. Circulation 95:3214- 3220, 1996.

33. Lemler M, Schaffer MS. Neonatal supraventricular tachycardia: Predictors of successful treatment 8 withdrawal. Am Heart J 1:130-131, 1997.

34. Graham K, Sondheimer H, Schaffer M. Resolution of cavopulmonary shunt-associated arteriovenous malformation after heart transplantation. J Heart Lung Transplant 16:1271-1274, 1997.

35. Kugler JD, Danford DA, Houston K, Felix G and Members of the pediatric EP Society, Radiofrequency Ablation Registry. Radiofrequency Catheter Ablation for Paroxysmal Supraventricular Tachycardia in Children and Adolescents Without Structural Heart Disease. Am J Cardiol 80:1438-1443, 1997.

36. Ivy DD, Neish SR, Knudson OA, Nihill MR, Schaffer MS, Tyson W, Abman SA, Shaffer EM,Valdez-Cruz L. Intravascular Ultrasonic Characteristics and Vasoreactivity of the Pulmonary Vasculature in Children with Pulmonary Hypertension. Am J Cardiol 81:740-748, 1998.

37. Boris JR, Drose JA, Schaffer MS, Shaffer EM. SPONTANEOUS RESOLUTION OF ATRIOVENTRICULAR DISSOCIATION IN UTERO. Pediatr Cardiol 19:487-489, 1998.

38. Schaffer MS, Snyder AM, Morrison JE. An Assessment of Desflurane for Use During Cardiac Electrophysiologic Study and Radiofrequency Ablation of Supraventricular Arrhythmias in Children. Paediatric Anaesthesia 10:155-159, 2000.

39. Schaffer M, Gow RM, Moak JP, Saul JP, and Participating Members of the Pediatric Electrophysiology Society. Mortality Following Radiofrequency Catheter Ablation (From the Pediatric Radiofrequency Ablation Registry). Am J Cardiol 86:639-643,2000.

40. Saul J, Schaffer M, Karpawich P, Epstein M, Ross B, Beerman L. Single Dose PK of Sotalol in a Pediatric Population with Supraventricular and/or Ventricular Tachyarrhythmia. J Clin Pharmacol 41(1):35-43, 2001.

41. Ozer S, Allen S, Schaffer M. Adenosine and Verapamil Sensitive Ventricular Tachycardia in the Newborn. PACE 24:898-901, 2001.

42. Ozer S, Schaffer M. Sinus Node Reentrant Tachycardia in a Neonate. PACE 24:1038-1040; 2001.

43. Brekke D, DeGroff C, Schaffer M. Changing Electrocardiographic Patterns During Medical Treatment in a Patient With Anomolous Left Coronary Artery Originating From the Pulmonary Artery. Circulation 103:e85-e86;2001.

44. Saul JP, Ross B, Schaffer MS, Beerman L, Melikian AP, Shi J, Williams J, Barbey JT, Jin J, Hinderling PH. Pharmacokinetics and pharmacodynamics of sotalol in a pediatric population with supraventricular and ventricular tachyarrhythmia. Clin Pharmacol Ther Mar;69(3):145-57;2001.

45. Van Hare GF, Carmelli D, McFate Smith W, Kugler JD, Silka, MJ, Friedman R, Atkins D, Saul JP, Schaffer MS, Byrum C, Dunnigan,A, Colan S, Serwer G. and Participating Members of the Pediatric Electrophysiology Society. Prospective Assessment after Pediatric Cardiac Ablation: Design and Implementation of the Multicenter Study PACE 25:332-341;2002.

46. Dubin AM, Berul CI, Bevilacqua LM, Collins KK, Etheridge SP, Fenrich AL, Friedman RA, Hamilton RM, Schaffer MS, Shah M, Silka MJ, Van Hare GF, Kertesz NJ. The use of implantable cardioverter-defibrillators in pediatric patients awaiting heart transplantation. J Card Fail. Oct; 9(5): 375-9; 2003.

47. Van Hare GF, Javitz H, Ph.D, M.D., Carmelli D, Ph.D., Saul JP, M.D., Tanel RE, Fischbach PS, KanterRJ, Schaffer MS. Dunnigan A, Colan S Serwer G and Participating Members of the Pediatric Electrophysiology Society. Prospective Assessment after Pediatric Cardiac Ablation: Recurrence At One Year After Initially Successful Ablation of Supraventricular Tachycardia Heart Rhythms 1:188-196; 2004.

48. Van Hare GF, Javitz H, Ph.D, M.D., Carmelli D, Ph.D., Saul JP, M.D., Tanel RE, Fischbach PS, KanterRJ, Schaffer MS. Dunnigan A, Colan S Serwer G and Participating Members of the Pediatric Electrophysiology Society. Prospective 9 Assessment after Pediatric Cardiac Ablation: Demographics, Medical Profiles, and Initial Outcomes J Cardiovasc Electrophysiol 15:759-70; 2004.

49. Schaffer, Michael S. Idiopathic Ventricular Tachycardia in the Young TURKISH JOURNAL of ARRHYTHMIA, PACING and ELECTROPHYSIOLOGY 3 (2, No.3 Supp 1):77-85; 2005.

50. Wathen JE, Rewers, AB,Yetman AT, Schaffer MS. Accuracy of ECG Interpretation in the Pediatric Emergency Department Ann Emerg Med 46:507-11;2005.

51. Beroukhim RS, Reed JH, Schaffer MS, Yetman AT. Surgical correction of mitral valve prolapse: a cure for recurrent ventricular tachycardia in Marfan syndrome? Pediatr Cardiol. 2006 Nov-Dec;27(6):755-8.

52. Van Hare GF, Colan SD, Javitz H, Carmelli D, Knilans T, Schaffer M, Kugler J, Byrum CJ, Saul JP and Participating Members of the Pediatric Electrophysiology Society. Prospective assessment after pediatric ablation: Fate of intracardiac structure and function, as assessed by serial echocardiography Am Heart J 2007; 153:815-20.e6.

53. Collins KK, Van Hare GF, Kertez NJ, Law IH, Bar-Coher Y, Dubin AM, Ethridge SP, Berul CI, Avari JN, Tuzcu V, Sreeram N, Schaffer MS, Fournier A, Sanatini S, Snyder CS, Smith RT, Arabia L, Hamilton R, Chun T, Liberman L, Kakavand B, Paul T, Tanel RE. Pediatric Nonpost-Operative Junctional Ectopic Tachycardia Medical Management and Interventional Therapies J Am Coll Cardiol 53:690-7;2009.

54. Howley LW, Di Maria M, Bailey A, Schaffer MS. Neonatal Long QT Syndrome Type 3 Predicted by Positive Lidocaine Challenge. Pacing Clin Electrophysiol. 2010 Mar;33(3):377-9

55. Collins KK, Runciman M, Rausch CM, Schaffer MS. Toward improved cosmetic results: a novel technique for the placement of a pacemaker or internal cardioverter/defibrillator generators in the axilla of young patients. Pediatr Cardiol. Nov 2009;30(8):1157-1160.

56. Collins KK, Silva JN, Rhee EK, Schaffer MS. Use of a wearable automated defibrillator in children compared to young adults. Pacing Clin Electrophysiol. 2010 Sep;33(9):1119-24.

57. McCanta AC, Collins KK, Schaffer MS. Incidental Dual Atrioventricular Nodal Physiology in Children and Adolescents: Clinical Follow-Up and Implications. Pacing Clin Electrophysiol. 2010; 1-5

58. Rausch CM, Hughes BH, Runciman M, MB, Law IH, Bradley DJ, Sujeev M, Duke A, Schaffer MS and Collins KK. Axillary Versus Infraclavicular Placement for Endocardial Heart Rhythm Devices in Patients With Pediatric and Congenital Heart Disease Am J Cardiol 2010;106:1646 –1651.

59. Rausch CM, Schaffer M, Collins KK. Ventricular ectopy following successful cryoablation for Wolff-Parkinson-White syndrome in the right posterior septum: a case report. Congenit Heart Dis. 2010 Nov;5(6):614-9.

60. Collins KK, Schaffer MS Use of cryoablation for treatment of tachyarrhythmias in 2010: survey of current practices of pediatric electrophysiologists. Pacing Clin Electrophysiol. 2011 (34);304-8.

10 61. Bat T, Collin KK, Schaffer MS. SYNCOPE DURING EXERCISE, JUST ANOTHER BENIGN VASOVAGAL EVENT? Curr Opin Pediatr. 2011;23:573-575.

62. McCanta AC, Schaffer MS, Collins KK Pediatric and Adult Congenital Endocardial Lead Extraction or Abandonment Decision (PACELEAD) Survey of Lead Management. Pacing Clin Electrophysiol. 2011; 1-7

63. Villasenor M, Schaffer MS, Collins KK. Cryoablation for Presumed Atrioventricular Nodal Reentrant Tachycardia in Pediatric Patients. Pacing Clin Electrophysiol. 2012 Sep 4. doi: 10.1111/j.1540-8159.2012.03507.x. [Epub ahead of print]

64. Bartakian S, Fagan TE, Schaffer MS, Darst JR. Device closure of secundum atrial septal defects in children <15 kg: complication rates and indications for referral. JACC Cardiovasc Interv. 2012 Nov;5(11):1178-84.

65. Collins KK, Schaffer MS, Liberman L, Saarel E, Knecht M, Tanel RE, Bradley D, Dubin AM, Paul T, Salerno J, Bar-Cohen Y, Sreeram N, Sanatani S, Law IH, Blaufox A, Batra A, Moltedo JM, van Hare GF, Reed J, Ro PS, Kugler J, Anderson C, Triedman JK; Pediatric and Congenital Electrophysiology Society. Fascicular and nonfascicular left ventricular tachycardias in the young: an international multicenter study. J Cardiovasc Electrophysiol. 2013 Jun;24(6):640-8. doi: 10.1111/jce.12105. Epub 2013 Feb 25.

66. Kang KT, Etheridge SP, Kantoch MJ, Tisma-Dupanovic S, Bradley DJ, Balaji S, Hamilton RM, Singh AK, Cannon BC, Schaffer MS, Potts JE, Sanatani S. Current Management of Focal Atrial Tachycardia in Children: A Multi-Center Experience. Circ Arrhythm Electrophysiol. 2014 Jul 11. pii: CIRCEP.113.001423. [Epub ahead of print]

67. Di Maria M, Seltz L, Schaffer M, Auerbach S, Younoszai A, Darst J, Howley L. Pediatric Resident Academic Half-Day: Cardiology. MedEdPORTAL Publications; 2015.

68. Kiger ME, McCanta AC, Tong S, Schaffer M, Runciman M, Collins KK. Intermittent versus Persistent Wolff-Parkinson-White Syndrome in Children: Electrophysiologic Properties and Clinical Outcomes. Pacing Clin Electrophysiol. 2016 Jan;39(1):14-20. doi: 10.1111/pace.12732. Epub 2015 Sep 11.

XIII. BOOKS AND REVIEWS

1. Schaffer MS, deSouza ME, Gilday DL, Rowe RD. Pediatric nuclear cardiology-applications and utility. In: Pediatric Cardiology and Cardiosurgery, Belloli GP, Ed., Modern Problems in Pediatrics: Vol 22,pp 26-37. S. Karger, Comp. New York, New York. 1982.

11 2. Schaffer MS, Gilday DL. Pediatric Nuclear Cardiovascular Medicine. In: Nuclear Cardiovascular Medicine. Eds. Lyons KP,Appleton and Lange,Norwalk, CT. 1988.

3. Balderston SM, Schaffer MS. Temporary Cardiac Pacing in Infants and Children. In: Bartecchi CE Ed., Temporary Cardiac Pacing. Precept Press Inc. Chicago, IL. 1990.

4. Pearse LA, Schaffer MS. Cardiovascular Disease. In: Silver, Kempe, Bruyn and Fuginiti's Handbook Pediatrics 16th Edition, Eds: Merenstein GB, Kaplan DW, Rosenberg AA. Appleton and Lange, Norwalk, CT. 1991.

5. Schaffer MS. Cardiovascular Drugs. In: Formulary of Accepted Drugs and Drug Dosing Handbook. 1st edition. Staible SA ed. Lexi-Comp Inc. Hudson, OH, 1992.

6. Shaffer EM, Pearse LA Schaffer MS. Cardiovascular Disease. In: Silver, Kempe, Bruyn and Fuginiti's Handbook Pediatrics 17th Edition, Eds: Merenstein GB, Kaplan DW, Rosenberg AA. Appleton and Lange, Norwalk, CT,1994.

7. Wolfe RR, Boucek MM, Schaffer MS, Wiggins JW. Cardiovascular Diseases. In: CURRENT Pediatric Diagnosis & Treatment, 12th edition. Eds: Hay WW, Groothius JR, Hayward, AR, Levin MJ. Appleton and Lange, Norwalk, Ct. 1995.

8. Schaffer MS. Cardiovascular Drugs. In: Formulary and Drug Dosing Handbook. The Children’s Hospital Denver Staible SA ed. Lexi-Comp Inc. Hudson, OH, 1996.

9. Wolfe RR, Boucek MM, Schaffer MS, Wiggins JW. Cardiovascular Diseases. In: CURRENT Pediatric Diagnosis & Treatment, 13th edition. Eds: Hay WW, Groothius JR, Hayward, AR, Levin MJ. Appleton and Lange, Norwalk, Ct. 1997.

10. Ivy DD, Shaffer EM, Schaffer MS. Heart. In: Handbook of Pediatrics 18th Edition. Eds: Merenstein GB, Kaplan DW, Rosenberg AA. Appleton and Lange, Norwalk, CT,1997.

11. Ziegler JW, Schaffer MS. Drug Abuse and Adverse Cardiovascular Effects In: The Science and Practice of Pediatric Cardiology, second edition. Eds: Garson A Jr., Bricker JT, Fisher DJ, Neish SR. Williams & Wilkins, Baltimore, Md, 1998.

12. Wolfe RR, Boucek MM, Schaffer MS, Wiggins JW. Cardiovascular Diseases. In: CURRENT Pediatric Diagnosis & Treatment, 14th edition. Eds: Hay WW, Hayward, AR, Levin MJ, Sondheimer JM. Appleton and Lange, Norwalk, Ct. 1999.

13. Sondheimer HM, Boucek MM, Ivy DD, Lorts A, Schaffer MS, Wolfe RR. Cardiovascular Diseases. In: Eds: Hay WW, Hayward, AR, Levin MJ, Sondheimer JM. Current Pediatric Diagnosis & Treatment, 15th edition. Appleton and Lange, Norwalk, Ct. 2001.

14. Sondheimer HM, Boucek MM, Ivy DD, Lorts A, Schaffer MS, Wolfe RR Cardiovascular Diseases. In: Eds: Hay WW, Hayward, AR, Levin MJ, Sondheimer JM. Current Pediatric Diagnosis & Treatment, 16th edition. Appleton and Lange, Norwalk, Ct. 2003.

15. Schaffer MS. Cardiovascular Disorders. In: Ed: Berman, Stephen. Pediatric Decision Making 4th edition. Mosby, Philadelphia, Pennsylvania, 2003.

16. Schaffer MS. Cardiovascular Disorders. In Ed: Bajaj L, Hambidge S, Kerby G, Nyquist A. Berman’s Pediatric Decision Making 5th edition. Elsevier Mosby, Philadelphia, Pennsylvania, 2011.

XIII. ABSTRACTS

12 1. Schaffer MS, Zuberbuhler P, Wilson G, Rose V, Duncan WJ, Rowe RD. Catecholamine cardiomyopathy. Presented at the Canadian Cardiovascular Society. Winnipeg, Manitoba, Canada. October 24, 1980.

2. Fowler RS, Schaffer MS. Importance of chest size in measuring left ventricular enlargement from the ECG in children with aortic stenosis. Presented at the Canadian Cardiovascular Society. Winnipeg, Manitoba, Canada. October 24, 1980.

3. Rowe RD, Schaffer MS. Some aspects of radionuclide investigation in pediatric cardiology. Presented at the International Congress of Pediatric Cardiology and Cardiac Surgery. Vicenza, Italy. October 1, 1981.

4. Schaffer MS, Freedom RM, Rowe RD. Infantile hypertrophic cardiomyopathy. Presented at the Canadian Cardiovascular Society. Winnipeg, Manitoba, Canada. October 30, 1981.

5. Schaffer MS, Rose V, deSouza M, Regelink E, Gilday DL, Rowe RD. Exercise radionuclide angiography with phase analysis in children with familial hypercholesterolemia. Presented at the International Symposium on Coronary Arteries in Infants and Children. Tel Aviv, Israel. October 17-22 ,1982.

5a. Also presented at the Society of Nuclear Medicine. St. Louis, MO. June,1983.

6. Nouri S, Hyberg E, Schaffer MS, Pennington DG, Waggoner A. Evaluation of digital subtraction angiography in coarctation of the aorta. Clin Res 31:209A, 1983.

7. Nouri S, Hyberg E, Schaffer MS, Sabet S. Reliability of echocardiography compared with cardiac catheterization in assessment of severity of aortic stenosis. Clin Res 31:209A, 1983.

8. Pelech A, Schaffer MS, Carusi P et al. A comparision of Amipaque and Renografin 76 in infants with ventricular septal defects and transposition of the great arteries. Canadian Cardiovascular Society. Quebec City, Quebec, Canada. October 17, 1984.

9. Schaffer MD, Cowgill D, Wiggins JW, Wolfe RR, Francis P, Campbell D. Aortic and mitral valve replacement with the St. Jude medical cardiac valve (SJMV) in infants and children. Second World Congress of Pediatric Cardiology. New York, New York. June 1985.

10. Wiggins JW, Daberkow E, Schaffer MS, Wolfe RR, Francis PD, McCarthy JP.Percutaneous transluminal balloon valvuloplasty (PBTV) in infant pulmonary stenosis (PS). American Academy of Pediatrics, Section on Cardiology. 27th meeting. San Antonio, TX. October 18-20, 1985.

11. Wolfe RR, Fasules JW, Schaffer MS, Sondheimer HM, Washington RL, Wiggins JW. Effects of Hypoxia and Ketamine on pulmonary vascular resistance. Presented at the American Academy of Pediatrics. Washington,DC.October 1986. American Heart Journal 112:646, 1986.

12. Abman SH, Schaffer MS, Wiggins JW, Washington RL, Manco-Johnson M, Wolfe RR. Pulmonary Vascular Extraction of Circulating Norepinephrine in Infants with Bronchopulmonary Dysplasia. Western Society for Pediatric Research. Carmel, CA. February 1987.

12a. Also presented at the Society for Pediatric Research.

13. VanGundy J, Schaffer MS, Wolfe RR, Daberkow E. Effects of Exercise in Patients with Known Congenital Prolonged QT Syndrome. American Academy of Pediatrics. New Orleans, LA. October 1987.

13a. Also presented at North American Society of Pediatric Exercise Medicine. Aspen, CO. August 1987.

14. Loehr JP, Washington RL, Wiggins JW, Sondheimer HM, Schaffer MS, Wolfe RR. Primary Pulmonary Hypertension in Pediatric Patients at Altitude. Western Society for Pediatric Research. Carmel, CA. February 1987.

15. Allen SW, Chatfield BA, Koppenhafer SL, Schaffer MS, Wiggins JW,Wolfe RR, Abman SH. Circulating Immunoreactive Endothelin-1 (irET-1) and Hypoxic Pulmonary Vasoconstriction in 13 Childhood Pulmonary Hypertension. Society for Pediatric Research. May 1992. Pediatric Research 31 (4) part 2:16A, 1992.

16. Pediatric Electrophysiology Society Radiofrequency Catheter Ablation Registry: RADIOFREQUENCY CATHETER ABLATION IN CHILDREN AND ADOLESCENTS; EARLY RESULTS IN 189 PATIENTS FROM 13 CENTERS. North America Society for Pacing and Electrophysiology. Chicago, IL. PACE 15(II): 889, 1992.

17. Ivy DD, Loehr JP, Schaffer MS. Prolonged Prostaglandin Infusion in Neonates with Severe Ebstein's Anomaly of the Tricuspid Valve. World Congress of Pediatric Cardiology and Cardiac Surgery. Paris, France. June,1993.

18. Morrison JE, Schaffer MS. Cardiac arrhythmias during induction and electrophysiologic mapping (EPM) and radiofrequency ablation (RFA). American Acadamy of Pediatrics. Denver, Co. April, 1994.

19. Morrison JE, Schaffer MS. Asseement of Halothane for Use During Electrophysiologic Studies in Children. Association of Paediatric Anaesthetists (APA-GARP). Florence, Italy. October 6- 8, 1994.

20. Scott WA, Pongiglione G, Bromberg BI, Schaffer MS, Deal BJ, Fish FA, Dick M, for the Pediatric Electrophysiology Society. Comparison of Treatments for Neurally Mediated Syncope. American Heart Association, November 14-17, 1994, Dallas, Texas. Circulation 1994; 90(II): I- 98.

21. Deal BJ, Dick M, Beerman l, Silka M, Walsh E, Klitzner T, Kugler J and Members of the Pediatric Electrophysiology Society. Cardiac Arrest in Young Patients with Wolff-Parkinson- White Syndrome. North American Society for Pacing and Electrophysiology, Boston Mass. May 5-7, PACE 18(II): 814, 1995.

22. Kugler J. Houston K. and the other members of the Pediatric Electrophysiology Society. Pediatric Radiofrequency Catheter Society for Pacing and Electrophysiology, Boston Mass. May 5-7, PACE 18(II): 814, 1995.

23. Schaffer MS, Silka MJ, Ross BA, Kugler JD. Inadvertent Heart Block During Pediatric Radiofrequency Catheter Ablation: Results of the Pediatric Ablation Regbistry. American Acadamy of Pediatrics, San Fransisco, California, October 13-15, 1995

24. Kugler JD, Danford DA, Felix G, Houston K and other participating members of the Pediatric Electrophysiology Society. Follow-up of Pediatric , Orlando, Florida, November 16, 1995, Circulation 92(I): I-764, 1995. Radiofrequency Catheter Ablation Registry Patients. American Heart Association

25. Lemler MS, Schaffer MS. . Transeophageal Electrophysiologic Studies to Predict Early Recurrences of Neonatal Supraventricular Tachycardia. American Heart Association, Orlando, Florida, November 16, 1995, Circulation 92(I): I-764, 1995.

26. Snyder A, Schaffer M. Atrioventricular Tachycardia in Children: Diagnosis, Management and Outcome. The Children's Hospital/University of Colorado Poster Session, February 2, 1996.

27. Ridout RE (MD/SOM), Schaffer MS, Valdez-Cruz LM. CONGENITAL COMPLETE HEART BLOCK: A DOPPLER ECHOCARDIOGRAPHIC ASSESSMENT OF DIASTOLIC FUNCTION. Western Society of Pediatric Research, Carmel, California, February 27, 1996.

28. Ivy D, Neish S, Knudson O, Schaffer M, Wiggins J, Shaffer E, Nihill M, Valdez-Cruz L. Intravascular Ultrasound of Pulmonary Arteries in Children With Pulmonary Hypertension. American College of Cardiology, Orlando, Florida, March 27,1996. J Am Coll Cardiol 27 (A): 324A, 1996.

29. Perry JC, Iverson P, Kugler JD and other Pediatric EP Society Members. Radiofrequency Catheter Ablation of Tachyarrhythmias in Young Patients with Structurally Abnormal Hearts. North American Society for Pacing and Electrophysiology, Seattle, Washington, May 16, 14 1996. PACE 19(II): 579, 1996.

30. Snyder AM, Morrison JE, Schaffer MS. Assessment of desfluane anesthetic during electrophysiologic study of supraventricular arrhythmias in children. The Second World Congres of Pediatric Cardiology and Surgery, Honolulu, Hawaii, May 11-15, 1997.

31. Kugler J, Danford D, Houston K, Felix G and other members of the Pediatric Radiofrequency Society. Pediatric radiofrequency catheter ablation (RCA) Registry: update of immediate results. The Second World Congres of Pediatric Cardiology and Surgery, Honolulu, Hawaii, May 11-15, 1997.

32. Schaffer MS, Gow RM, Moak JP, Saul JP: MORTALITY FOLLOWING RADIOFREQUENCY CATHETER ABLATION: RESULTS OF THE PEDIATRIC RADIOFREQUENCY ABLATION REGISTRY. American Acadamy of Pediatrics, San Fransisco, California, OCTOBER16-21, 1998., PEDIATRICS, 102 (2): 672, 1998.

33. Schaffer Michael S MD, Houston, Kris RN MSN BA, Felix Gary MS, Kuglar John MD. COMPLICATIONS OF RADIOFREQUENCY CATHETER ABLATION: RESULTS OF THE PEDIATRIC RADIOFREQUENCY ABLATION REGISTRY. 5th INTERNATIONAL DEAD SEA SYMPOSIUM ON ADVANCES IN DIAGNOSIS AND TREATMENT OF CARDIAC ARRHYTHMIAS DEAD SEA, ISREAL, FEBRUARY 29-MARCH 3, 200O.

34. Saul JP, Schaffer MS, Ross B, Beerman L, Erickson CC, Karpawich PP, and the Pediatric Sotalol Investigators; Melikian AP, Williams JH, Shi J, Barbey JT, Hinderling PH. Pharmacokinetics and Pharmacodynamics of Sotalol in a Pediatric Population: Results of the First Controlled PK/PD Study of an Antiarrhythmic Agent in Children. American College of Cardiology, Anaheim, California, March 12-15,2000.

35. Ozer S, Allen S, Schaffer M. Adenosine and Verapamil Sensitive Ventricular Tachycardia in the Newborn. The 3rd World Congress of Pediatric Cardiology and Cardiac Surgery. Toronto, Ontario, Canada. May 27-31, 2001.

36. Ozer S, Schaffer M. Sinus Node Reentrant Tachycardia in a Neonate The 3rd World Congress of Pediatric Cardiology and Cardiac Surgery. Toronto, Ontario, Canada. May 27-31, 2001.

37. M. Schaffer, S. Schaffer. NEONATAL SVT: PREDICTORS OF RECURRENCE FOLLOWING TREATMENT WITHDRAWL. The XII World Congress on Cardiac Pacing and Electrophysiology. Hong Kong, China. February 19-22, 2003.

38. George F. Van Hare, Dorit Carmelli, J. Philip Saul, Ronn Tanel, Peter S. Fishbach, Ronald Canter, Michael Schaffer. Prospective Assessment After Pediatric Cardiac Ablation-Initial Results of the Multi-center Study. American College of Cardiology, Chicago, Ill, March 27-31, 2003.

39. Wathen JE, Rewers, AB,Yetman AT, Schaffer MS. Pediatric Electrocardiogram Interpretation Accuracy in a Pediatric Emergency Department 2003 Pediatric Academic Societies' Annual Meeting in Seattle, Washington, May 3-6.

40. Li Zhang, MD, Tiehua Chen, PhD, Michael Sheets, MD, Robert L. Lux, PhD, Michael S. Schaffer, MD, Elizabeth Charuvastra, RN, William E. Shell, MD and G. Michael Vincent, MD. LDS Hospital, Univ of Utah, Salt Lake City, UT, CVRTI, Univ of Utah, Salt Lake City, UT, Children's Hospital, Univ of Colorado, Denver, CO, Laboratory Industry Services, LLC, Los Angeles, CA. A SCN5A mutation caused ST elevation, transient QT prolongation and sudden death: an atypical phenotype of Brugada-long QT syndrome? Heart Rhythm Society, New Orleans, LA., May 4-7,2005.

41. Schaffer, TS, Waksman JC and Schaffer MS. Rocky Mountain Poison and Drug Center, Denver CO, and University of Colorado Health Sciences Center, Denver CO. Accidental Overdose of Verapamil in an Infant From Series of Medical Errors. North American Congress of Clinical Toxicology, Orlando Fla, Sept 2005.

42. Michael Schaffer, MD, Andrea Vitello, BS, Derek Patton, Martin Runciman, MBBS

15 The Children’s Hospital/ University of Colorado School of Medicine Is Electroanatomic Mapping and Navigation beneficial? A retrospective comparison of the impact of electroanatomic mapping and navigation in pediatric patients with supraventricular arrhythmias and AVNRT Pedirhythm III, Istanbul Turkey, October 6-10, 2007.

42. Elias ER, Garrington, T, Schaffer M, Swisshelm K, Geiersbach K. Ring Chromosome 6 with Wilms Tumor and Tetralogy of Fallot. ACMG mtg, March 2007, Nashville, TN

44. McCanta AC, Collins KK, Schaffer MS. Are Findings of Dual Atrioventricular Nodal Physiology Predictive of Atrioventricular Nodal Reentrant Tachycardia? Heart Rhythm society, Boston, MA. May 13-16, 2009.

44a. McCanta AC, Collins KK, Schaffer MS. Are Findings of Dual Atrioventricular Nodal Physiology Predictive of Atrioventricular Nodal Reentrant Tachycardia? World Congress of Pediatric Cardiology and Cardiac Surgery, Cairns, Australia, June 21-26, 2009.

45. Kristopher T. Kang, BA, Susan P. Etheridge, MD, Michal J. Kantoch, MD, Michael S. Schaffer, MD, Bryan C. Cannon, MD, David J. Bradley, MD, Robert J. Hamilton, MD, Svjetlana Tisma- Dupanovic, MD, James E. Potts, PhD and Shubhayan Sanatani, MD, FHRS. MANAGEMENT OF ATRIAL ECTOPIC TACHYCARDIA IN CHILDREN IN THE CURRENT ERA: A MULTI-CENTER EXPERIENCE Heart Rhythm Journal 8(5) May 2011. p S232