UCSF Lab Standard Operating Procedure s26

UCSF Lab Standard Operating Procedure

Chemical Process, Name or Hazard Class: Lithium Silicon

Please fill out the form completely. Insure all users have access to this SOP. Refer to instructions for assistance. Department: Enter text. Date SOP was written: Enter date. This lab specific SOP has been reviewed and approved by: Principal Investigator Name: Enter text. Principal Investigator Signature Lab Manager/Supervisor: Enter text.

Type of SOP: ☐ Process ☒Hazardous Chemical ☐ Hazardous Class

Purpose

Lithium silicon is highly flammable and water reactive. Contact with water liberates flammable gases. Dangers of serious damage to health by prolonged exposure through inhalation. Extreme caution is advised. Keep away from heat and sources of ignition. Material poses extreme risk of explosion by shock, fire, friction or other sources of ignition.

Is harmful if swallowed, inhaled, or in contact with skin or eyes. Toxic if inhaled and is extremely destructive to the tissue of the mucous membranes and upper respiratory tract.

Lithium silicon is an metal alloy of lithium and silicon.

Physical & Chemical Properties/Definition of Chemical Group

CAS#: 68848-64-6

Class: Highly flammable, Water reactive

Molecular Formula: LiSi

Form (physical state): solid

Color: grey

Lithium Silicon 1 Date: Click here to enter a date. Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/) Boiling point: N/A

Potential Hazards/Toxicity

Lithium silicon is highly flammable and water reactive. Contact with water liberates flammable gases. Dangers of serious damage to health by prolonged exposure through inhalation. Extreme caution is advised. Keep away from heat and sources of ignition. Material poses extreme risk of explosion by shock, fire, friction or other sources of ignition. Is harmful if swallowed, inhaled, or in contact with skin or eyes.

Lithium exposure can cause dizziness and weakness and kidney damage can result. There may be dehydration, weight loss, skin effects and thyroid disturbances. Can cause central nervous system effects that include slurred speech, blurred vision, numbness and convulsions. Repeated exposure can cause diarrhea, vomiting, tremor, muscle jerks and very brisk reflexes. Chronic exposure to lithium compounds can affect the nervous system and muscle.

The following permissible exposure limit data is available: 0.025 mg/m3 TWA

No acute toxicity data is available.

Engineering Controls

Handle using a chemical fume hood with good ventilation and electrically grounded lines and equipment.

Personal Protective Equipment (PPE)

Respirator Protection If lab personnel would like to use respirator on a voluntary basis, they must be trained and fit-tested by EH&S. This is a regulatory requirement. (http://or.ucsf.edu/ehs/8193-DSY/version/default/part/4/data/)

Hand Protection Gloves must be worn. Use proper glove removal technique to avoid any skin contact. Nitrile gloves are recommended.

NOTE: Consult with your preferred glove manufacturer to ensure that the gloves you plan on using are compatible with Lithium silicon.

Refer to glove selection chart from the links below: http://www.ansellpro.com/download/Ansell_8thEditionChemicalResistanceGuide.pdf OR http://www.allsafetyproducts.biz/page/74172 OR http://www.showabestglove.com/site/default.aspx OR http://www.mapaglove.com/

Eye Protection ANSI approved properly fitting safety glasses or chemical splash goggles. Face shield is also recommended.

Skin and Body Protection Flame resistant/cotton lab coats must be worn and be appropriately sized for the individual and buttoned to their full length. Laboratory coat sleeves must be of sufficient length to prevent skin exposure while wearing

Lithium Silicon 2 Date: Click here to enter a date. Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/) gloves. Full length pants and close-toed shoes must be worn at all times by all individuals that are occupying the laboratory area. The area of skin between the shoe and ankle should not be exposed.

Hygiene Measures Wash thoroughly and immediately after handling. Remove any contaminated clothing and wash before reuse.

First Aid Procedures

If inhaled Move into the fresh air immediately and give oxygen. If not breathing give artificial respiration. Seek medical attention immediately.

In case of skin contact Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash any contaminated clothing before reuse. Thoroughly clean shoes before reuse. Seek medical attention immediately.

In case of eye contact Check for and remove any contact lenses. Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Seek immediate medical attention and continue eye rinse during transport to hospital.

If swallowed Do NOT induce vomiting unless directed by medical personnel. Never give anything by mouth to an unconscious person. Seek medical attention immediately.

Special Handling and Storage Requirements

Precautions for safe handling: Flammable, handle away from heat and sources of ignition. Avoid shock or friction. Avoid contact with skin and eyes and inhalation. Avoid inhalation of vapor or mist. Avoid formation of dust.

Conditions for safe storage: Flammable, store away from heat and sources of ignition. Avoid shock or friction. Flammable materials should be stored in a flammable storage cabinet. Keep in a dry place. Keep container tightly closed in a cool, dry, and well ventilated. Keep away from incompatible materials and conditions. Keep cool and protect from sunlight.

Spill and Accident Procedure Chemical Spill Dial 9-911 from campus phone or 415-476-1414 from cell phone or 415-206- 8522 (SFGH only)

Spill – Assess the extent of danger. Assist contaminated or injured persons. Evacuate the spill area. Avoid breathing vapors. If possible, confine the spill to a small area using a spill kit or absorbent material. Keep others from entering contaminated area (e.g., use caution tape, barriers, etc.).

Small (<1 L) – If you have training, you may assist in the clean-up effort. Use appropriate personal protective equipment and clean-up material for chemical spilled. Double bag spill waste in clear plastic bags, label and take to the next chemical waste pick-up.

Large (>1 L) – Dial 9-911 from campus phone or 415-476-1414 from cell phone or 415-206- 8522 (SFGH only) for assistance.

Lithium Silicon 3 Date: Click here to enter a date. Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/) Chemical Spill on Body or Clothes – Remove clothing and rinse body thoroughly in emergency shower for at least 15 minutes. If discomfort persists, proceed to the Emergency Department. If no further discomfort is experienced, have the SDS ready and contact Poison Control Hotline at 1-800- 222-1222 for further exposure information. Notify your direct supervisor and EH&S at 415- 476-1300 during work hours, or 9-911 during non-working hours and weekends.

Chemical Splash Into Eyes – Immediately rinse eyeball and inner surface of eyelid with water for 15 minutes by forcibly holding the eye open. If discomfort persists, proceed to the Emergency Department. If no further discomfort is experienced, have the SDS ready and contact Poison Control Hotline at 1-800-222-1222 for further exposure information. Notify your direct supervisor and EH&S at 415-476-1300 during work hours, or 9-911 during non-working hours and weekends.

Medical Emergency Dial 9-911 (campus phone) or 476-6911 (cell phone)

Note: All serious injuries must be reported to EH&S at 415-476-1300 within 8 hours.

Non-Life Threatening Emergency– Go to Occupational Health Programs (OHP) Clinic, 415-885- 7580, 2330 Post Street, Suite 460 Hours of Operation for Appointments: Monday - Friday 7:30 a.m. - 4:00 p.m. (except Holidays).

Note: All serious injuries must be reported to EH&S at 415-476-1300 within 8 hours.

Needle stick/puncture exposure (as applicable to chemical handling procedure) – Wash the affected area with antiseptic soap and warm water for 15 minutes. For mucous membrane exposure, flush the affected area for 15 minutes using an eyewash station. Page the needle stick nurse by dialing 415-353-7842 (STIC).

Decontamination/Waste Disposal Procedure

Clean contaminated surfaces with soap and water and paper towels. Dispose of the paper towels as hazardous waste.

Safety Data Sheet (SDS) Location

Online SDS can be accessed at http://or.ucsf.edu/ehs/7241-DSY/msds.html

Protocol/Procedure

Quantities covered by this SOP: ______(g , ml) to ______(g, ml)

Temperature range covered by this SOP: __ °C – __ °C

General Overview and Purpose:

Lithium Silicon 4 Date: Click here to enter a date. Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/) Enter the experimental purpose

Procedure: Enter experimental procedure. You can copy procedure from your lab notebook or from literature.

Any deviation from this SOP requires approval from the Principal Investigator.

Lithium Silicon 5 Date: Click here to enter a date. Modified from SOP templates developed by UCLA EH&S (http://www.sop.ehs.ucla.edu/)