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7-1949 Washington University Medical Alumni Quarterly, July 1949

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Recommended Citation Washington University Medical Alumni Quarterly, July 1949. Bernard Becker Medical Library Archives. Washington University School of Medicine, Saint Louis, Missouri. http://digitalcommons.wustl.edu/med_alumni_quarterly/46

This Article is brought to you for free and open access by the Washington University Publications at Digital Commons@Becker. It has been accepted for inclusion in Washington University Medical Alumni Quarterly by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. OFFICERS OF THE ALUMNI ASSOCIATION OF WASHINGTON UNrVERSITY SCHOOL OF MEDICINE

President: Dr. Dalton K. Rose '15 Vice-President: Dr. James Barrett Brown '23 Vice-President: Dr. A. N. Arneson '28 Secretary-Treasurer: Dr. George W. Ittner '37

Executive Committee Term. Expires 1950 Term Expires 1951 Term Expires 1952 Dr. J. W. Thompson '23 Dr. Guy Magness '28 Dr. Walter Baumgarten, Jr. '39 Dr. Louis H. Jorstadt '24 Dr. Delevan Calkins '31 Dr. Joseph C. Jaudon '33 Dr. Oliver Abel, Jr. '23 Dr. Sim F. Beam '32 Dr. David N. Kerr '40 Dr. Samuel B. Grant '24 Dr. Oscar C. Zink '21 Dr. A. Victor Reese '28

EDITORIAL BOARD WASHINGTON UNIVERSITY MEDICAL ALUMNI QUARTERLY

Representing the University: Representing the Alumni: Dr. Robert J. Terry '95 Dr. Louis Jorstad '24 Dr. Alexis Hartmann. '21 Dr. James W. Bagby '33 Dr. Paul Hageman '34 Dr. Leo Wade, '38 Dr. Robert A. Moore, Editor

Office of the Washington University Medical Alumni Quarterly, Euclid and Kingshighway, St. Louis 10, Missouri

Published quarterly by Washington University School of Medicine, St. Louis 10, Mo. Entered as second class matter December 14, 1937, at the Post Office at St. Louis, Mo., under the act of August 24, 1912. The Washington University Medical Alumni Quarterly

I VOL. XII JULY, 1949 NO. 4

The Development and Application of Radiographic Equipment for the Automatic Rapid Serialization of X-Ray Exposures — the Tautograph and the Rapidograph By Wendell G. Scott, M.D. Department of Radiology and the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Mo.

In the past decade radiologists have read a report by Dr. Hans Jarre de- made intense efforts to improve and scribing a "Cinex Camera" which he make practical techniques for visualiz- had developed and used in the radio- ing the arterial and venous system of graphic examination of the urinary the body and of the heart. Relatively tract in 1928. After corresponding with innocuous chemicals that are opaque to Dr. Jarre, I went to Detroit to see this x-rays have been available, but the chief equipment. He had not used it for sev- stumbling block was the lack of auto- eral years, but it was still workable. It matic equipment that was capable of was a compact, ingenious device, and making a series of x-ray exposures in was the first to use x-ray roll film. It rapid sequence with a Potter-Bucky grid could accommodate sizes varying from to obtain films of satisfactory clarity 4 to 11 inches in width. It was capable and contrast. of making exposures at the rate of one The object of this paper is to describe every one-half second. At that time, un- the development of two successful units fortunately, the transformers and x-ray for this purpose, the tautograph and the tubes did not have sufficient capacity to rapidograph, the latter having been se- permit using a Potter-Bucky grid with lected for commercial production and the Cinex Camera and consequently the distribution. roentgenograms lacked contrast. It was The idea of using a large continuous for this reason largely that Dr. Jarre roll of x-ray film to examine function- was unable to interest the manufactur- ing organs within the body first occurred ers in developing his "Camera" for gen- to me in 1935 when I was trying to eral use and the project was set aside. adapt kymography to the study of the The hope of ultimately using roll excretory mechanism of the kidney and film for the examination of functioning ureter. In reviewing the literature, I organs persisted in my thoughts and in 108 WASHINGTON UNIVERSITY

1945 I witnessed a demonstration of a gained by such equipment was the fact Fairchild aerial camera in the Photo- that a single and smaller injection of graphic Department at a Naval Air Sta- the opaque chemical would suffice and tion. This camera utilized a film 9y2 would avoid the repeated injections of inches wide and came in rolls about larger amounts as were frequently nec- ti- 100 feet long. This seemed like a feas- essary then to fully visualize a particu- ible unit to adapt to radiographic pur- lar structure. poses. Through the proper channels I With this background the answer nts secured the magazine of this camera seemed to be in using large size x-ray ID and had started to alter it for "spot roll film adapted to the magazine of film" work in gastro-intestinal exami- the Fairchild Aerial Camera such as we v nations when the war ended and put a had tried earlier, and altering it to run stop to this undertaking. at a fast rate of exposure with all oper- With the return to peace-time status, ations for advancing and stopping the

I soon realized that the pediatricians, film and making the x-ray exposure i the cardiologists, the thoracic surgeons, completely automatized and synchro- and the neurological surgeons were all nized with a Potter-Bucky grid to obtain interested in improving their angio- films of the greatest contrast and clar- graphic techniques whereby an opaque ity. After going over the problem with chemical, usually an iodine compound, Dr. Sherwood Moore, Professor of Ra- > was injected into the blood stream and diology and Head of the Department, roentgenograms were made as it passed we decided it was feasible to make a il••- through the heart and lungs, or through unit of this order. Accordingly, in De- the arteries of the brain. In a study of cember, 1946, I arranged a meeting with these procedures, it was apparent that Mr. C. E. Seibert of the Fairchild Cam- ;- the most urgent need was the develop- era Company in New York, where we ment of x-ray equipment that could take went over our objectives. He kindly a continuous series of pictures in rapid gave us a war surplus magazine of their K sequence during the time the opaque A-5 aerial camera. After making pre- T chemical was circulating through the liminary drawings of the alterations organs or vessels to be pictured. This, and additions, Dr. Moore and I con- furthermore, should be done with auto- sulted Mr. R. H. Tontrup of St. Louis matically operated equipment to elimi- and arranged for him to carry out the nate the failures caused by manual oper- mechanical construction. ation and by teams of technicians that Many interesting problems were pre- were organized to change the individual sented for solution in this undertaking, x-ray films. The rapid serialization of for instance: X-ray film is coated with «' x-ray exposures, plus assured auto- photo-sensitive emulsion on both sides matic operation would make these an- and has a stiff cellulose base to prevent giographic techniques practical every- curling so that it will lie flat. The stand- day diagnostic procedures. An addi- ard photographic film is coated only on , tional and important advantage to be one side and has a soft cellulose base MEDICAL ALUMNI QUARTERLY 109

that curls easily. The magazine was or- out included the installation of the two iginally designed to handle the pliable intensifying screens at the top of the photographic film which was flattened magazine through which the x-ray film and immobilized in the magazine by an would be exposed; the construction of air suction system at the moment of ex- cams that would raise and lower one of posure. The x-ray film, however, was the intensifying screens to permit the not only too stiff to be affected by this passage of the film and then bring them vacuum system, but for our purpose the together quickly and in firm contact film had to be exposed between two during the exposure; synchronization of intensifying screens which could not be the movement of the Potter-Bucky grid perforated for air holes. The problem to occur at the moment the film was was solved by making a large cam that stopped and the x-ray exposure made; raised and lowered the plate supporting the construction of a device for recock- the underneath intensifying screen. In ing the Potter-Bucky grid while the ex- this way greater pressure could be ex- posed x-ray film was taken up and the erted by the lower screen against the new unexposed segment of film brought 11 upper and the film between them flat- into position. ■ 4 tened and immobilized for the exposure. All of these factors and others had Also, the magazine was designed to be to be accomplished in accord with our powered by interlocking discs on the top basic premise that the finished unit surface, but for radiographic purposes would be small, compact and removable it was necessary to place the Potter- from the x-ray table so it could be taken Bucky grid as close to the top of the to the darkroom where the exposed roll magazine as possible with just enough of film could be removed and processed. clearance to permit the grid to move. We wanted to retain as many of the Consequently, a new drive shaft had to basic construction features of the maga- be constructed at the side of the maga- zine as possible in order that the same zine and connected with a motor. tools, dies, castings, etc., that were used The selection of the motor was not in the construction of the magazine for easy as the type, power, size, speed, and the Army Air Forces could be used in i«K combination of reduction gears had to the construction of the rapidograph. be determined with respect to the ex- This was important because it meant posure rate at which the unit was to a great saving in the manufacturing operate. cost which was necessary if it was to One of the most difficult problems was be available to the smaller radiological to speed up the rate of exposure from departments with limited funds. one every two seconds to an exposure After considerable work and many rate of one every one-half second with- trials with repeated revisions, the above factors were all accomplished. The ■>jt: out damaging the original gears and bearings so the expense of constructing rapidograph is now in commercial pro- new and heavier ones could be avoided. duction by the Fairchild Camera Com- Other changes that had to be worked pany, which has arranged to distribute 110 WASHINGTON UNIVERSITY

it through the companies manufacturing was a big step forward because it offered x-ray equipment. It operates at an ex- a means for visualizing the different posure rate of one every one-half second chambers of the heart and the great and mechanical failures have been re- blood vessels leading to and from it. duced to practically zero. The unit is This was done by quickly injecting an flexible and can be adapted by any opaque chemical into an arm vein and manufacturer to fit his diagnostic tables then taking two roentgen films at the of practically every vintage and model. estimated moments it was passing If the radiologist prefers, the rapido- through the right and left sides of the graph can be set into a special end table heart. Their technique, however, was which can be rolled into position. Some only practical in the examination of radiologists may even prefer to mount adults who could remain immobile, it on a Potter-Bucky grid stand or on control their respiration and stand erect head and sinus units. against a standard chest cassette changer. Furthermore, it necessitated CLINICAL APPLICATIONS the determination of the circulation time The first application of the rapido- in order to "guesstimate" the exact time graph was in the study of children and the "bolus" of opaque chemical would infants with congenital malformations arrive in a particular part of the of the heart. The brilliant develop- heart and then make the roentgen ex- ments in cardio-vascular surgery by posure at that moment. It was difficult Gross of Boston, Blalock of Baltimore, to accomplish this on only two films, and Potts of Chicago had stimulated but that was as many as could be taken great interest in these disorders, because in rapid sequence by standard equip- for the first time something could be ment. Consequently, in many instances done for patients afflicted with them. a second and even a third injection were Many had been rehabilitated by cardiac required to obtain satisfactory visualiza- surgery and restored to lead a normal tion of the heart and lung circulation. and active life. Unfortunately, not all Multiple injections increased the hazard types of congenital cardiac disorders of the examination and were to be could be corrected by surgical meas- avoided. Thus, while angiography was ures, and therefore, it became more im- an achievement it was not practical for portant to diagnose accurately every the examination of children and infants patient and to appraise him as to and new techniques had to be devised if whether or not he was a suitable candi- the little ones who needed it the most date for surgery. In other words, a real were to be benefited. That is why we need existed for better radiograph: c devised the tautograph and the rapido- means of visualizing these defects in the graph. heart and great blood vessels. l Robb, G. P., and Steinberg-, I., Practical The introduction of angiocardiog- Method of Visualization of the Chambers of the Heart, and Pulmonary Circulation, and raphy by Robb and Steinberg1 in 1938 the Great Blood Vessels in Man. Journal Clinical Investigation, 193S, 17, 507. Side view of Tautograph constructed for the rapid serialization of individual x-ray cassettes. It operates at a continuous rate of one exposure per second. The bottom cassette in the maga- zine at head of table is car- ried under the patient by the chain conveyor, is stopped there for the exposure and is then retired into receiving bin on the floor at end of table. The Tautograph was the first fully automatized equipment synchronized with a Potter-Bucky grid for obtaining a series of films in quick succession.

Side view of total equipment with Dr. Wendell G. Scott holding the Rapidograph and pointing to the timing pin which closes the micro- switch for starting the Potter- Bucky grid which in turn initiates the x-ray exposure and turns it off. The light- proof cover has been re- moved from the magazine to demonstrate the supply and take-up spools with the large size x-ray roll film. The top of the Potter-Bucky grid has been taken off to show the grid and self-cock- ing mechanism. Two x-ray tubes at right angles to each other have been set up.

Dr. Wesley Fee, Assistant Resident in Radiology, is demonstrating the technique for making cardio-vascular angiograms. A special syr- inge and needle are inserted into the arm vein and the opaque material (diodrast 70% or neo-iopex 75%) in- jected extremely quickly. Mr. Ferguson, x-ray techni- cian, starts exposures by pressing button before the injection is made and keeps it closed throughout the in- jection and from six to twelve seconds thereafter. Note electric motor and reduction gear unit beneath the table and connected to magazine by drive shaft. 112 WASHINGTON UNIVERSITY

The tautograph is a radiographic unit was fast enough to eliminate the move- which I designed with the support of ments of respiration. Excellent angio- Dr. Sherwood Moore and which was grams were obtained by this method, constructed by Mr. R. H. Tontrup prior but we were not yet satisfied. We wanted to the development of the rapidograph. a faster rate of exposure; equipment of The tautograph handles standard x-ray less bulk and weight; a unit more flex- cassettes which are moved by a roller ible and adaptable to existing radio- chain conveyor system beneath the top graphic equipment; one with less vibra- of the table between two channel irons tion and noise and capable of almost an equipped with brass rollers. A stack of unlimited number of exposures. The 10 or more ll"xl4" cassettes are placed rapidograph was, of course, the answer in the magazine at the head of the table to these problems and today it has made and the bottom one is picked off by a cardio-vascular angiography in chil- steel lug on the roller chain and carried dren a practical and a safer diagnostic into position beneath the patient's chest procedure. where it is stopped for % of one second In this respect we should like to em- while an x-ray exposure of 1/20 of one phasize the great help and cooperation second is made. This cassette is then we have received from Dr. Merl J. Car- carried to the end of the table into a son, Assistant Professor of Pediatrics receiving bin at the same time a new and Dr. Thomas H. Burford, Associate cassette is brought into position. By Professor of Surgery. They contributed this process a large number of films can largely to the actual technique of the in- be made in quick succession. The en- jections. In working so closely together, tire mechanism is automatized and only the whole project has had the benefit of one technician is required to close one "team" action. The small infants are switch in order to put the equipment in given a bottle of sugar water to suckle operation. For the first time the tauto- during the preparation and examina- graph offered radiologists a means of tion. A few cc of novocain are injected taking films in rapid sequence with a into the skin over the left antecubital Potter-Bucky grid. This meant that the vein. A small incision is made in the cardio-pulmonary circulation could now bleb and the largest needle compatible be visualized independently of the cir- with the diameter of the vein is then culation time, without having to pre- inserted. The amount of 70% diodrast determine the exposure time, without or 75% neo-iopex injected depends on the hazard of repeated examinations, the size of the patient as well as on the without the assistance of a "crew" of size of the heart. At a given signal the technicians, and with the assurance and rapidograph is started and two ex- constancy of mechanical control. For posures are made before the chemical the first time we had a practical tech- is quickly injected (within iy2 sec- nique for angio-cardiography in chil- onds). The rapidograph continues tak- dren and infants. The roentgen ex- ing films throughout the injection and posure was 1/20 of one second which for 8 to 10 seconds thereafter. The MEDICAL ALUMNI QUARTERLY 113 needle is then withdrawn and the skin into a major artery of the neck or edges sutured together. shoulder against the direction of the It might be well to review that in 10 blood flow. It is used primarily for seconds of operation, the rapidograph obtaining a clearer visualization of the takes 20 roentgenograms on a strip of aorta and its branches. Drs. Burford film 9V2 inches wide and 22 feet long. and Carson developed independently of Each exposure is 1/20 of one second, others the technique of using the left and for the twenty exposures a total of common carotid artery with the needle only one second of x-ray is used. This inserted toward the aorta so that when feature makes it safe to take this number the chemical is injected, it is forced di- of films and is the great advantage rectly into the aorta. This procedure has gained over photo-fluorographic tech- been especially helpful in the visualiza- niques which photograph the image on tion of coarctations of the aorta for the fluoroscopic screen on small 70 mm. locating the exact level of the constric- roll film. Our process and photo-fluorog- tion, the degree of narrowing and the raphy are entirely different and should extent to which the collateral circula- not be confused. tion has developed. It has also been In our experience cardio-vascular an- valuable in confirming a patent ductus giography by this method has been very arteriosis as some of the chemical in- helpful, not only in the confirmation of jected into the aorta will pass through the clinical diagnosis, but also as a the patent ductus into the pulmonary thorough method of visualization of the arteries where it is visualized without cardio-pulmonary circulation for addi- having passed through the heart. Aortog- tional defects and abnormal physiologic raphy usually requires the surgical ex- changes. In general cardiovascular an- posure of the left common carotid ar- giography has been useful in the recog- tery for the direct insertion of the nition of and the distinction between needle. tetralogy of Fallot and Eisenmenger's Perhaps even a greater field of use- complex. It has also proved advan- fulness for the rapidograph lies in its tageous in the diagnosis of truncus- application to cerebral angiography. arteriosis, tricuspid stenosis wtih a so- Here, too, the technique of examination called "non-functioning" right ventricle, was previously handicapped by the lack true transposition of the great vessels, of radiographic equipment capable of interventricular septal defects, stenosis making a series of roentgenograms in of the pulmonary conus or infundib- rapid sequence, in this case while a ulum, double aortic arches, right-sided "bolus" of opaque chemical was circu- aortic arch and other anomalies. lating through the arterial system of the A word should be mentioned about brain. In the past the basic idea was aortography as distinguished from to obtain visualization of the cerebral cardio-vascular angiography. Aortog- arterial system by keeping it filled raphy is done by injecting the 70% with a continuous injection of the diodrast or 75% neo-iopex retrograde opaque chemical while taking a long 114 WASHINGTON UNIVERSITY

x-ray exposure of two to three seconds throughout the injection and for 3 to 4 duration. A second or occasionally a seconds thereafter. Since the rapido- third film was made immediately fol- graph provides a continuous series of lowing the first in an effort to picture films taken every half second, it is pos- the chemical in the capillaries and later sible now to inject much smaller quan- in the venous system. By this same tities of the chemical and record the method two films could be made in progress of this single "bolus" through rapid sequence by shifting the tube be- the arterial system, the capillary stage, tween the exposures to obtain stere- and the venous system. Large quanti- scopic views. Frequently this technique ties of the chemical are no longer re- was successful, but too often it was not, quired. This is an advantage in the per- due to a failure of manual operation in cutaneous method because if the artery the timing, in the handling of the cas- is "missed" and the chemical injected settes and the synchronization of the into the soft tissues of the neck only events. Consequently, repeated injec- 5 to 7 cc are misplaced, compared to tions were commonly required for ade- 15 to 30 cc as formerly. With the quate visualization with a minimal smaller amounts it is possible to repeat boost in the hazard of the examination. the injection without fear of harmful By applying the rapidograph, a safer, consequences. simpler, more accurate, and positive Stereoscopic studies can also be made technique has been evolved by "teaming by taking the first series of films with up" with the Department of Neurolog- the x-ray tube shifted iy2 inches to one ical Surgery, of which Dr. Henry side of the mid-line and taking the sec- Schwartz is Professor. In using the ond series after a second injection, with rapidograph the human element was the tube shifted \y2 inches to the oppo- eliminated from the radiographic tech- site side of the mid-line. The two films nique, and the only source of failure-in in each series that demonstrate the best the examination now rests with the phy- filling of the arteries are then placed in sician who is making the actual injection the stereoscopic viewer. Anterior-poste- of the 30% diodrast into either the rior views are made following a third right or left common carotid artery. injection. The total amount of the Both the per-cutaneous technique and chemical now used for the three routine the injection directly into the exposed injections about equals the amount for- artery are performed at the discretion merly used for a single injection. of the neurological surgeon. Just prior Another advantage offered by the to the injection the rapidograph is set serial roll film in cerebral angiography in operation by the technician and at is that it provides a means of checking least two "plain" films are made before a suspicious filling defect in any artery the signal to injection the chemical is on any one exposure by comparing its given. The injection here is also done appearance on films made 1/2 second very quickly, within one second, and the prior and y2 second later than the one roentgen exposures are continued in question. In same way the radiolo- MEDICAL ALUMNI QUARTERLY 115 gist has a means of establishing that could be fitted with a Morgan exposure- such a questionable filling defect is con- time, mounted on an upright stand and stant and thus of definite significance. equipped with a self-centering and Other fields of diagnostic radiology counter - balancing mechanism. The in which the rapidograph is promising whole unit, together with a shockproof are in the visualization of arterial and tube, transformer, and control, could be venous diseases involving the extrem- placed in a convenient room. Anyone ities. At present these studies are lim- desiring a chest film could step into a ited by the relatively small area that dressing booth, remove his clothing can be x-rayed, but as developments in down to the waist, slip on a paper cape, the adaptation of roll film mature, write his name and other pertinent in- larger rapidographs employing larger formation on an identification card films sufficient to include the entire leg fitted on the front of the rapidograph, or arm will be available. As in cardio- place his chain in a slot for this pur- vascular angiography, an opaque chem- pose, take a deep breath, and at the end ical (30% diodrast or 35% neo-iopex) of 5 seconds the x-ray exposure would is injected into the artery or vein in be turned on automatically and turned question and serial films are made to off by the Morgan timer to produce a demonstrate the distribution of the ves- perfect chest film. The patient would sel, the size of the lumen and the loca- then return to the dressing booth, and tion of the occlusion, aneurysm, or the next person could step into position. arterial-venous shunt. No technician would be required and Preliminary studies are also under even the secretary might be omitted. way for using the rapidograph as a At the end of the day the roll of ex- means of investigating the range of mo- posed film would be removed by the tion of a joint or even of a segment of dark room technician. Thus several the spine. Exposures are made as the hundred people could be examined daily patient slowly moves the joint from a at their own convenience at a much position in full flexion to full extension. lower cost, with the assurance that films This not only gives film in the extreme providing the very best detail were be- positions, but also in the intermediate ing used to detect disease. stages. In closing it should be mentioned An intriguing .future use for the that the rapidograph represents the first rapidograph would be to adapt it to practical utilization of large size x-ray automatic self-operating machines for roll film for diagnostic radiographic survey purposes. For example, in con- purposes. As such, it is the forerunner ducting surveys of the chest for pulmo- of new and important developments in nary tuberculosis, the rapidograph diagnostic radiology. 116 WASHINGTON UNIVERSITY Proceedings of Washington University Medical Society

The Borden Undergraduate Research fraternity. The names were announced Award for 1949 was presented to Milo at the May 19 meeting, and juniors Lawrence Heideman, Jr., '49, at the elected were: Seymour Advocate, Elmer Washington University Medical Society B. Brown, Jr., William M. Hebert, Rob- meeting held May 19. The $500 award ert Rochman, and J. Max Rukes. Those was given for his winning paper on elected from the senior class were: Man "Studies on the Pharmacology of p-Ami- Hing Au, Leonard Berg, Warren L. noethylbenzenesulf onamide (Sulf amy- Felton II, Ralph H. Forrester, Ervin lon,)" which Dr. Heideman presented Lipschitz, Stanley L. London, Charles during the evening program. Other stu- P. McGinty, Miss Luigia Norsa, Marvin dent papers presented at the meeting Rosecan, Dale M. Schulz, Thomas J. were: "Investigation of Antidiuretic Walsh, Laurens P. White, and George Principles" by Stanley Rokaw, '49, and S. Woodard. The Nu Sigma Nu Awards "Constancy of Nucleic Acid and Phos- of $25 to the outstanding freshman and pholipid Phosphorus with aging in sophomore for the school year 1947-48 Mouse Liver" by Dale M. Schulz, '49. went to Philip S. Norman and Seymour Abstracts are printed herewith. Advocate, respectively. Alpha Omega Alpha announced the Abstracts of the papers presented at names of 18 junior and senior students the Society meetings on February 8, elected to membership in the honorary April 28, and May 19 follow.

Abstracts of Papers Presented on Feb- ruary 8, 1949: BLADDER RECONSTRUCTION FROM CECUM AND ASCENDING COLON FOLLOWING RESECTION OF PELVIC VISCERA by Eugene M. Bricker, M.D., and Ben Eiseman, M.D. Department of Surgery In this presentation the authors re- sciences and in view of the possibility introduced the procedure of ureteral of applying the procedure to the treat- transplantation to the terminal ileum ment of far advanced carcinoma of the and cecum with construction of a blind rectum with involvement of the trigone cecal pouch to act as a urinary reser- of the bladder. Two illustrative cases vois. This procedure, which was first were reported. One a man of 68 years, done in 1908 by Verhoogan, was deemed and the second a woman of 48 years, worthy of resurrection in view of the both of whom had complete evisceration recent advances in surgery and allied of the pelvis for carcinoma arising in ^H| ■■ flBB^HHH _j#

MEDICAL ALUMNI QUARTERLY 117

the rectum and rectosigmoid, with trans- with the function of the colostoiiiy which plantation of the ureters into the ter- in each case was a left inguinal one. minal ileum in the first case and into The patients were alive and well with- the cecum in the second. Kidney func- out evidence of recurrent tumor two tion remained good. There was appar- years and one year from the date of ently no deleterious effect from having the report. The functional result was the urinary stream diverted into the considered to be good. right colon. There was no interference

AGE CHANGES IN THE SALIVARY GLANDS Warren Andrew, Ph.D., M.D. Visiting Professor in Anatomy from George Washington University The submandibular gland of Wistar rotid gland. They are essentially large, Institute rats has been studied in a aberrant cells of the serous aveoli. series of animals ranging from 21 days They show marked nuclear changes, to 1170 days of age. In old age there The nucleoli of oncocytes are hypertro- is almost no fatty degeneration in this phied. Amitosis is common and the gland in the rat. This is in contrast to daughter nuclei tend to adhere together, the condition in the parotid glands of forming twin and triplet nuclei. With the same animals, where large masses increasing age, the granular parts of of parenchyma are destroyed by such the salivary ducts show more pycnotic a process. Oncocytes are as numerous and shrunken nuclei, the lumina are and as conspicuous in the senile sub- obscured, and infiltration by lympho- mandibular gland as in the senile pa- cytes is common.

NUTRITIONAL SURVEYS IN NEWFOUNDLAND Robert E. Shank, M.D., and Oliver H. Lowry, Ph.D., M.D. Departments of Preventive Medicine and Public Health, and Pharmacology Newfoundland has had, for many make two nutritional surveys, one in years, a record of poor nutrition. Begin- 1944, before the institution of the en- ning in 1944 the Newfoundland gov- richment program, and again in 1948, ernment took steps to improve the diet, after four years under the new program. through enrichment of the flour and The isolated nature of the community margarine, which resulted in a doubling and the fact that most of the food is of the average consumption of thiamine, important made the situation an ideal riboflavin, vitamin A, and calcium, and one for study. In both surveys there substantially increased the iron and were carried out clinical examinations nicotinic acid intake. The government of over 800 persons and chemical likewise invited a group of Canadian, analyses of blood and urine from half British and American investigators to that number. The same examiners and 118 WASHINGTON UNIVERSITY

the same chemical procedures were util- perhaps, calcium, and that in 1948 all ized in both surveys. Furthermore, of these, except ascorbic acid, had de- nearly a fourth of the persons were ex- cidedly improved. These findings ap- amined both in 1944 and 1948. Thus pear to be pertinent to our own enrich- differences observed would seem to be ment program. (The full report of unusually valid. In a remarkable man- these surveys is to be found in Aykroyd, ner the clinical and laboratory findings W. R., Jolliffe, N., Lowry, 0. H., Moore, agreed that in 1944 there existed at least P. E. Zemecnik, P.C., Canadian M.AJ. moderate deficiencies in riboflavin, thia- 60 1, (1949). mine, vitamin A and ascorbic acid, and,

Abstracts of Papers Presented on April 28, 1949:

THE PHYSIOLOGICAL BASIS OF PHYSICAL TREATMENT OF DISORDERS OF THE CORTICOSPINAL TRACT Sedgwick Mead, M.D. Physical Medicine The manifestations of corticospinal Rationale of Treatment tract disease vary considerably with the Loss of voluntary motor power is sel- location of the lesion and the degree of dom total, fortunately. Involvement is involvement of extrapyramidal systems. more serious in the upper extremity With this in mind, the chief defects than in the lower, possibly due to the might be listed as follows: loss of vol- uncrossed corticospinal tract running in untary motor power; increased sensi- the anterior funiculus of the cord which tivity of stretch reflexes; clonus; rigid- permits the latter to escape in part in ity—the loss of Sherringtonian recipro- a unilateral hemispheric lesion. Several cal inhibition and thus, the inability to weeks of total paralysis following cere- relax antagonist muscles; increased sen- bral thrombosis or embolism may be sitivity of anti-gravity reflexes; ataxia. succeeded by a gratifying return of vol- Additionally, secondary factors which unity power provided proprioceptors may be more disabling in the end are: and long-circuiting connections are stim- periarthritis (frozen shoulder) and ulated by passive motions and faradic shoulder-hand syndrome: disuse atro- current. Contractures and severe atro- phy of muscle, connective tissue, and phy are prevented. Reciprocal rhythmic bone; flexor-pronator contractures of exercises may aid in training alternate the elbow, wrist, and fingers; foot-drop control pathways, examples being: and external hip rotation. Oversolici- swimming and crawling motions on the tude may produce undue invalidism. If mat, bed bicycling, pulley exercises. present, auditory aphasia, alexia, agno- Possibly the rubro-, reticulo-, and ves- sias, or apraxias may make re-education tibulo-spinal tracts can be trained to nearly impossible. carry some of these impulses. m^^^mn^mi^g^mpi MHHI

MEDICAL ALUMNI QUARTERLY 119

Splints and bracing may be essential, acterized not only by lead-pipe or cog- for walking must be secured as early as wheel resistance to passive motion, but possible. When foot dorsiflexors are a tendency to contract all the muscles paralyzed a short-leg brace with spring of the extremity instead of the appro- device is employed. Braces may later priate ones on attempt at a voluntary be discarded as muscle power increases act. Preventive muscle re-education with use of progressive resistance exer- should be instituted in the early stages cises. of hemiplegia when the patient is apt Increased sensitivity of stretch re- to be flaccid. flexes is a "calculus" function—the ef- Disabling in the upper extremity, the fectiveness of a stretch stimulus is less anti-gravity responses may actually be dependent on its absolute magnitude turned to advantage in the lower extrem- than on the rate of change of onset of ity. If the patient cannot stand on his the stimulus. Over- reactions occur when feet, his spasticity may do it for him. the patient attempts a sudden motion or Rather than a corticospinal defect, is startled by a sudden sound or visual ataxia may signify no more than the image. He learns to avoid positions imprecision and dysmetria associated likely to initiate clonus and also that with muscle weakness from disuse and cold weather increases this problem. invalidism. At least it tends to dis- Rigidity is a difficult problem, char- appear with training.

ANTIGEN TRACER STUDIES AND HISTOLOGIC OBSERVATIONS IN ANAPHYLACTIC SHOCK IN THE GUINEA PIG Frank J. Dixon, Jr., M.D. Department of Pathology By labelling protein antigens with phylactic shock showed two factors to I131, radioactive isotope of iodine, and be instrumental in the production of using tracer techniques, we were able fatal bronchial obstruction. First, there to demonstrate a concentration of an- was a transitory contraction of the bron- tigen in the bronchial walls during ana- chial smooth muscle which was most phylactic shock. The antigen was local- apparent two minutes after the shock ized in the collagenous tissue of the injection and then gradually disap- bronchial walls external to the smooth peared. This muscle contraction was muscle layer. The concentration of anti best seen in egg albumen anaphylaxis i was apparently a specific uptake which terminated fatally in about two of antigen by sensitized tissue because minutes. Second, there was congestion labelled proteins which were not the of the blood and lymph vessels and specific shock producing antigen were edema formation in the collagenous tis- not concentrated in the bronchial wall sue of the bronchial wall, which ap- during shock. peared within a minute after the shock Histologic study of the lungs in ana- injection and progressed during shock. 120 WASHINGTON UNIVERSITY

In globulin induced anaphylaxis which tion and edema of the bronchial wall terminated fatally in from five to eight had become so marked that it appeared minutes, there was little or no evidence to be largely responsible for the bron- of muscle contraction, and the conges- chial obstruction.

ENHANCING EFFECT OF GROWTH HORMONE ON RENAL FUNCTION Harvey L. White, M.D.; Peter Heinbecker, M.D.; Doris Rolf, A.B. Departments of Physiology and Surgery Daily growth hormone administration loss of the gonadotropic and adreno- (Armour's 3PKR3) for 9 to 12 days tropic hormones is not responsible for doubled the PAH clearance and almost the great depressions of these renal doubled the inulin clearance and PAH functions seen after hypophysectomy, Tm in normal dogs and raised the and that the effect of loss of thyro- greatly depressed values of hypophys- tropic hormone is slight, the principal ectomized dogs to or above the normal effect is due to loss of growth hormone levels. It had but slight effect on these or of some substance not yet separated functions in the adrenalectomized dog from it. The enhancing effect of growth maintained on DCA pellets. Subsequent hormone on renal function may find batches have been effective in hypophys- some therapeutic application if consis- ectomized but not in normal dogs. In tently active preparations can be ob- view of our earlier demonstrations that tained.

THE USE OF RADIOACTIVE IODINE IN THYROID DISEASE William H. Daughaday, M.D. Department of Medicine The experience at Barnes Hospital dioactive iodine therapy. The surgical with the use of radioactive iodine in procedure was not made more difficult over 125 patients with hyperthyroidism by radioiodine. Twenty-one of the pa- was reviewed for the Society. Results tients exhibited varying degrees of hypo- obtained in the first 75 patients were thyroidism following radioiodine ther- discussed in detail. These patients were apy. From these studies, it was con- selected because they had recurrent cluded that radioactive iodine has hyperthyroidism, advanced age, or com- proved itself a valuable aid in the treat- plicating disease. Hyperthyroidism has ment of thyroid disease. The ease and been controlled in 51 of the 66 patients economy of its administration recom- on whom data were available. Six pa- mend it during these days of mounting tients were improved but not, as yet, medical costs. It effects a truly remark- euthyroid after variable periods of ob- able decrease in the size of even very servation. Two patients were subjected large diffuse goiters. It is inferior to to thyroidectomies following initial ra- thyroidectomy only in the speed of re- MEDICAL ALUMNI QUARTERLY 121 sponse and the higher incidence of post- roidism, the risk, although not great, treatment hypothyroidism. At present, of malignancy, should be considered in our opinion, it is the treatment of and weighed in the total situation. The choice in recurrent hyperthyroidism. Its possible carcinogenecity of radioiodine propensity of causing hypothyroidism has been judged to be slight on the basis makes radioiodine treatment of younger of its half-life although another decade patients less desirable than surgery. or so must pass before a better evalua- Radioiodine is not contraindicated in tion can be made. heart diseases, some of our best results Preliminary observations on 11 pa- having occurred in such patients. In tients with mestastic carcinoma of the the treatment of nodular goiters, radio- thyroid were presented. Of this group, iodine is useful in controlling hyper- two patients had relatively well-differ- thyroidism in the presence of old age entiated carcinomas adjudged suitable and severe complicating disease. Pa- for radioactive iodine therapy. No con- tients with large nodular goiters prob- clusions can be drawn at this time of ably do better with surgery. In the treat- the over-all effectiveness of this form of ment of nodular goiters with hyperthy- treatment in carcinoma of the thyroid.

Abstracts of Student Papers Presented on May 19, 1949: STUDIES ON THE PHARMACOLOGY OF P-AMINOMETHYLBENZENESULFONAMIDE (SULFAMYLON) M. Lawrence Heideman, Jr., M.D. '49

Previous workers have shown that actions were observed clinically, and no sulfamylon is not antagonized by para- evidence of renal damage or hemato- aminobenzoic acid and exerts some bac- poietic depression was found. tericidal effect. Its range of anti-bac- Sulfamylon is excreted rapidly. High terial activity has some differences from doses are required to attain appreciable that of other sulfonamides. blood levels (20 to 50 mg. per 100 ml. Marked individual variations in ab- after doses of 0.6 gm. per kg.), which sorption are evident after oral adminis- fall off rapidly; large amounts of free tration of sulfamylon, with absorption sulfamylon are detected in the urine very poor in infants, while the sub- within one to two hours after oral ad- ministration and disappear within eight cutaneous routeKJUIO provides^i^.^^— a- relatively uniform picture of rapid absorption and hours. Conjugated sulfamylon and para- somewhat higher blood levels. Immedi- carboxybenzene - sulfonamide also ap- ate symptoms of headache and nausea pear as excretion products in the urine. were reported by all patients taking Sulfamylon causes a pronounced diu- sulfamylon orally; mild dizziness and resis and production of markedly alka- mental confusion were experienced by line urine. The great urinary bicarbon- three out of eleven. No other toxic re- ate loss tends to be inhibited by base 122 WASHINGTON UNIVERSITY

need in the body, but may persist dur- concentrations far less than those at- ing maintenance therapy enough to pro- tained in the blood serum, but attains duce systemic acidosis, at least in pa- high levels in ascitic fluid. Concentra- tients with renal disease. tions in whole blood are equivalent to Sulfamylon enters the spinal fluid in those in serum.

CONSTANCY OF NUCLEIC ACID AND PHOSPHOLIPID PHOSPHORUS WITH AGE IN MOUSE LIVER Dale M. Schulz, M.D. '49 During the development of a tissue pooled livers of from three to five mice there are manifest changes in the syn- were homogenized and treated with thesis of protein by the cells of that various reagents so as to obtain four tissue. This is reflected in a general way phosphorus-containing fractions desig- by increase in size during growth and nated as acid-soluble, phospholipid, by atrophy of tissues with age. In re- ribonucleic acid, and desoxyribonucleic cent years there has been accumulating acid phosphorus, respectively, evidence pointing to a close connection Some twenty-five such sets were run between protein synthesis and the nu- using mice varying in age from three to cleic acids. Caspersson has made the thirteen months. For purposes of statis- observation that intense protein produc- tical analysis the values obtained for tion, as in embryonic tissue, cancer mice under two months of age were cells, or secret glands, is always asso- compared with the corresponding values ciated with an increase in nucleic acid for mice ten months old or older. It was concentration. It was therefore thought found that there was no significant dif- desirable to study nucleic acid concen- ference in any of the phosphorus-bear- tration as a function of age. ing fractions with aging. The tissue used for this study was This result may indicate that liver mouse liver, the animals being selected does not age in the sense that the indi- at random except that pregnant females vidual ages, or it may mean that quali- were not used. The nucleic acids were tative changes occur without detectable estimated in terms of phosphorus. The quantitative shifts.

INVESTIGATION OF ANTIDIURETIC PRINCIPLES Stanley N. Rokaw, M.D. '49, Bernard A. Bercu, M.D., and Edward Massie, M.D. Department of Medicine Many reports have recently chal- development of congestive failure have lenged the conventional explanations of excited much interest, and it was felt the mechanisms involved in cardiac de- important therefore, to investigate pa- compensation. The importance of kid- tients with congestive heart failure for ney function and water balance in the the presence of increased amounts of MEDICAL ALUMNI QUARTERLY 123 antidiuretic substances excreted in their cial pitressin. The potency of prepared urine. "positive" fifteen minute urine samples, Urines from normal individuals and in terms of milliunits of pitressin effect, from patients with mental illness (used assayed at 0.3 to 1.0 milliunits. The as controls), and the urines from pa- source of these substances in the car- tients with chronic congestive failure diac failure patient is not yet identified. and peripheral edema, were studied. Pa- Eleven Graduated Cum Laude; tients with definite kidney diseases or Annual Prizes Announced independent liver disease were excluded. The specimens were collected over Eleven members of the Class of 1949 known-time intervals, acidified, evapo- were graduated with the degree of Doc- rated at room temperature, and then tor of Medicine cum laude at Com- dialyzed against tap water for 6 to 24 mencement Exercises on June 7: hours. Amounts equivalent to fifteen Man Hing Au minutes of urine output (2 to 4 c.c.) Leonard Berg were used as the test dose, injected Ralph H. Forrester intravenously into a normal female dog Milo L. Heideman, Jr. in water diuresis. A preceding injection Robert H. Lund of commercial pitressin (0.1 milli unit) Charles P. McGinty was always made for comparison with Stanley N. Rokaw the antidiuretic response to the test dose. Marvin Rosecan Urines were collected from the dogs by Dale M. Schulz indwelling catheters, into volumetric Thomas J. Walsh containers, and output was measured at Laurens Park White four minute intervals. The annual prizes and awards in the A total of fourteen patients were School of Medicine are as follows: studied, with diagnoses of arterio-scle- George F. Gill Prize in Anatomy— rotic heart disease (7), rheumatic heart Peter P. Rowell disease (4), hypertensive heart disease George F. Gill Prize in Pediatrics— (4), cor pulmonale (2) and one of un- John E. Hult. determined etiology. Positive antidiu- Alpha Omega Alpha Book Prize— retic effects (abrupt reduction in urine Stanley R. Rokaw output after injection of the test sub- B o r d e n Undergraduate Research stance, followed by return to diuretic Award—Milo L. Heideman, Jr. output levels) were obtained in eleven Howard A. McCordock Prize in Pa- cases, while no antidiuretic effect was thology—John H. Knowles noted in the urine of three cardiac fail- Sidney Schwab Prize in Psychiatry ure patients. None of the control urines —Bertram J. Oppenheimer tested showed antidiuretic activity. In- Medical Fund Society Prize in Inter- vestigations indicated the antidiuretic nal Medicine—Stanley N. Rokaw substances present in cardiac-failure Medical Fund Society Prize in Sur- urine, were not identical with commer- gery—Man Hing Au. 124 WASHINGTON UNIVERSITY Dr. Sherwood Moore Succeeded by Dr. Hugh Wilson as Radiology Chief After 48 years spent as student and the old Washington University Hospital staff member at Washington University, on Jefferson Avenue, and was the first Dr. Sherwood Moore became professor resident in radiology at Massachusetts emeritus of radiology on July 1, at General Hospital. In the latter capacity, which time he was succeeded by Dr. Dr. Moore relates, he was actually the Hugh M. Wilson. Dr. Wilson, like Dr. first intern in x-ray specialization.

Dr. Sherwood Moore, '05 Dr. Hugh M. Wilson, '27

Moore, is an alumnus of the School of Born in Lynchburg, Va., in 1880, Dr. Medicine and will be professor of Moore attended the University of Vir- radiology and director of the Mallinck- ginia for one year prior to entering rodt Institute of Radiology. Washington University School of Medi- Dr. Moore has been connected with cine in 1901. Following his graduation the School of Medicine continuously in 1905, he spent one year at City Hos- since 1901, when he entered as a stu- pital as intern, then was senior resident dent, except for a brief one-year period in obstetrics at the W. U. hospital for as intern at the St. Louis City Hospital the following year. From 1907 to 1912 and for three years when he was travel- he was in the private practice of sur- ing and studying to prepare for his spe- gery, and was assistant in surgery at cial field. He was the first resident at Children's Hospital from 1910 to 1913. MEDICAL ALUMNI QUARTERLY 125

He was resident radiologist at Massa- Following his graduation from the Med- chusetts General Hospital in 1916-17. ical School here in 1927, Dr. Wilson In 1917, he was appointed assistant took his internship at the Royal Victoria in surgery and radiology in the Medical Hospital in Montreal, Canada, then re- School, and was associate in surgery turned to Barnes Hospital where he was from 1920 to 1927. He has been profes- on the surgical staff under Dr. Evarts sor of radiology since 1927 and director A. Graham from 1928 to 1930. He was of the Edward Mallinckrodt Institute of assistant radiologist to the Mallinckrodt Radiology since 1930. During this time, Institute when it opened in 1931 and Dr. Moore has been roentgenologist to spent the next three years studying Barnes, Children's, Maternity, McMillan under Dr. Moore, whom he now suc- and Shriner's Hospitals. ceeds. In 1934 he was called to the He has held military offices in both staff of Yale as assistant professor of World War I and II. From 1917 to radiology and advanced to head of the 1922 he was a lieutenant in the U. S. department there. Naval Reserve Medical Corps. For 20 Dr. Wilson, who is 47 years old, has years, from 1922 to 1942, he was major published many scientific papers on and, later, lieutenant colonel in the diagnostic radiology with reference to medical corps of the U. S. Army. obstetrics, diseases of the nervous sys- Among the honors which have been tem and of the chest. He was born in accorded Dr. Moore are: Gold Medal Jacksonville, 111., is married, and has of the St. Louis Medical Society (re- two daughters. ceived with Dr. Evarts Graham, Dr. Cancer Research Building Warren Cole, and Dr. Glover Copher) to Be Started in Fall in 1927; honorable mention by the A. M. A. and Canadian Medical Asso- Plans for the new cancer research ciation in 1935; Silver Medal of the building to be constructed between the American Academy of Orthopedic Sur- north and south wings of the present geons, 1936; honorable mention of the Medical School building are in the final Southern Medical Association, 1937; stages of preparation, and construction honorable mention at the Fifth Inter- is due to start before very long. national Congress of Radiology, 1937; Harris Armstrong, architect for the Bronze Medal of the Mississippi Valley project, is drawing up final plans for Medical Society in 1938; First Award construction work, and it is expected of the Radiological Society of North that bids will be let during the early America, 1939; certificates of merit fall. from the American Roentgen Ray So- The plans call for a $900,000 build- ciety in 1936 and from the A.M.A. in ing, when completed and equipped, which will connect with each of the 1936 and 1939. Dr. Wilson comes to the School of four floor levels in the present north Medicine from Yale University, where and south wings. The building will be he has been professor of radiology. of modern design. 126 WASHINGTON UNIVERSITY Preliminary Returns in the Student Dormitory Center Campaign The campaign for funds from the the total will amount to $540,174.80. medical school alumni for the new Stu- This amount can be supplemented by dent Dormitory Center has gotten off contributions from other sources, partic- to a good start. The total number of ularly from the parents of students and living graduates is 3,352. As this re- younger alumni. port goes to press, 163 alumni have sent I feel confident that the ideal Dormi- in pledges which total $26,566.00. Of tory Center will become a reality be- this amount, $13,369.15 has already cause the alumni are interested, and the been collected, and the remainder land on which it is to be built is already pledged to be paid in 1950 and 1951. owned by the University. It has been very gratifying to receive The following list shows those who several pledges for $1000.00, and fifteen have already made contributions or pledges for $500.00. It has also been pledges. The names are arranged in two a great satisfaction to note that some >ways. First, by classes, and second, by of the younger alumni, who are, still geographical trade areas, with the chair- serving as internes and residents, have man for the area listed, sent in pledges. These pledges were nee- Letters will be sent out periodically essarily for smaller amounts. in pursuance of the campaign. Those The average amount pledged has been who have not already contributed are $161.15. If each one of the 3,352 urged to do so at their earliest conven- alumni will make pledges to the fund, ience. and if this average can be maintained, Samuel B. Grant, Chairman

Medical Student Dormitory Fund Contributors from Each Class Number of Number of Class Living Graduates Class Living Graduates 1948 90 1943 (Dec.) 112 1947 oy Terrell Covington, Jr., McKinney, Tex. Tn"""Charles i ~rG. "7-.","Clay, "TRantoul, V'TV, 111. Mary Jordan, Ridley' Park, Pa. Burner W. Peden, St. Louis 1943 (March) 95 Virginia H. Peden, St. Louis Raymond M. Charnas, St. Louis Harlan I. Firminger, Bethesda, Md. 1946 92 Melvin L. Goldman, St. Louis ■ James W Owen, Jr., Guam, M. I. Eichi Masunaga, Hawaii .Frank Vellios, Guam, M. I. IT,.„„,,♦ c 1? c T? • r. ,-r T J T xrr- J i_- T-V wi ™, Ernest b. Kogers, ban Irancisco, vCahf1 Leonard J. Wiedershine, Ft. Warren, Wyo. 1 T CL \I ,, ' -"»" - ' rCarvel 1. Shaw, Hermann, Mo. 1945 97 Ira W. Leibner, Brooklyn, N. Y. John T. Johnstone, Jr., St. Louis 1942.. no Roscoe Maxwell, Punta Gorda, Fla. Herman Rice, Temple,' Texas Eugene E. Taylor, Mocksville, N. C. -IQ.-I 1944 99 Peter 6. Fleming^' TopekaT Kan". Rowe F Bisbee, Ada, Okla. Anne T. Goetsch, Berkeley, Calif. MEDICAL ALUMNI QUARTERLY 127

Number of Number of Class Living Graduates Class Living Graduates Geo. Bruce Lemmon, Springfied, Mo. 1933 88 Harold E. McCann, E. St. Louis, 111. James W. Bagby, St. Louis C. A. Nielsen, Seattle, Wash. C. A. Good, Rochester, Minn. Joseph W. Noah, St. Louis Carl G. Harford, St. Louis ' Carol H. Rehm, Los Angeles, Calif. W. W. Herman, Cleveland, Ohio 1940 90 Joseph C. Jaudon, St. Louis Donald S. Bottom, Alton, 111. Lyman K. Richardson, New Orleans, La. Russell J. Crider, St. Charles, Mo. Richard Y. Sakimoto, Honolulu, T. H. Robert E. Koch, St. Louis Lawrence M. Wilson, Olympia, Wash. Gordon F. Moore, Alton, 111. 1932 85 Willard D. Rowland, Portland, Ore. Sim F. Beam, St. Louis Seymour Brown, St. Louis Louis T. Byars, St. Louis William Ehrlich, Newark, N. J. 1939..3 96 Alfred K. Baur, St. Louis Leo Gottlieb, St. Louis Heinz E. Cron, San Francisco, Calif. Carl V. Moore, St. Louis Edward H. Reinhard, St. Louis Sydney S. Pearl, Elizabeth, N. J. C. O'Neil Rich, Salt Lake City, Utah Minton D. Ritter, Margate City, N. J. Wendell G. Scott, St. Louis 1938- 93 Barrett L. Taussig, St. Louis Anthony Piraino, Oberlin, Ohio Sam R. Wallis, Kauai, T. H. Philip Rosenblatt, New York, N. Y. Helman C. Wasserman, St. Louis 19377 93 1931 73 Samuel Brady, Gary, Ind. Mary Louise Newman, Jacksonville, III. Martin A. Compton, Richmond, Va. Robert F. Monroe, Louisville, Ky. Charles M. Polan, Huntington, W. Va. Delevan Calkins, St. Louis Henry N. Reid, Rome, N. Y. Lloyd Rosenbaum, Anderson, Ind.- 1930 74 Herbert H. Gass, St. Louis William H. Gray, Yakima, Wash. I. D. Newmark, Chester, 111. 1936.. 96 F. R. Crouch, Farmington, Mo. 1929 72 Norman W. Drey, St. Louis Louis Kovitz, Kansas City, Mo. Stephen Ellis, Coffeyville, Kan. Frank B. Queen, Portland, Ore. Nathan R. Kahn, Brooklyn, N. Y. Jay Marvin Salzman, Springfield, 111. Frank McDowell, St. Louis 1928 68 James D. Morrison, Billings, Mont. A. N. Arneson, St. Louis R. A. Nussbaum, St. Louis Justin J. Cordonnier, St. Louis 1935.. 89 H. R. Hildreth, St. Louis I. J. Fiance, St. Louis J. T. Jean, St. Louis A. H. Hutto, St. Louis . R. D. Kepner, Honolulu, T. H. Bruce Kenamore, St. Louis L. A. Malone, Terre Haute, Ind. Edward Massie, St. Louis John F. Patton, St. Louis Ben H. Senturia, St. Louis A. Victor Reese, St. Louis A. J. Steiner, St. Louis Verne Ross, Stockton, Calif. W. A. Ruch, Memphis, Tenn. 1934.4 S. D. Soule, St. Louis Helen M. Aff, St. Louis Vincent Williams, Kansas City, Mo. James M. Baker, Columbia, Mo. Eugene M. Bricker, St. Louis 1927 72 David Friedman, Granite City, 111. A. C. Fortney, Fargo, N. D. Stanley Hampton, St. Louis Alfred G. Henrich, Los Angeles, Calif. Louis G. Jekel, Phoenix, Ariz. W. R. Merrell, Brigham City, Utah Dorothy J. Jones, St. Louis Kazuo Miyamoto, Honolulu, Hawaii Morris D. Marcus, St. Louis Eugene 0. Parsons, Kansas City, Mo. Edna Schrick, Holland, Mich. Willard C. Schwartz, Manhattan, Kan. 128 WASHINGTON UNIVERSITY

Number of Number of Class Living Graduates Class Living Graduates Frances H. Stewart, St. Louis 1914. 8 Louis L. Tureen, St. Louis 1913 21 W. B. Wilcoxen, Bowling Green, Mo. Omar Sevin, St. Louis 1926 74 1912 30 William B. Kountz, St. Louis Edwin C. Ernst, St. Louis H. M. Chandler, Waipahu, T. H. 1911 23 Max Deutch, St. Louis Charles H. Hecker, Palo Alto, Calif. 1925 69 1910 41 Robert J. Crossen, St. Louis Frederic Hagler, Springfield, Mass. H. M. Denny, Union, Mo. 1909 31 James J. Donohue, E. St. Louis, 111. 1908 33 Richard K. Kimmel, St. Louis 1907 29 Melvin A. Roblee, St. Louis 1906 35 Gershom J. Thompson, Rochester, Minn. S. P. Martin, East Prairie, Mo. William H. Smith, Colfax, Calif. 1924 69 Roy F. Baskett, Texarkana, Texas 1905 12 Elizabeth E. Koppenaal, Elmhurst, 111. Walter Fischel, St. Louis O. Earl Whitsell, St. Joseph, Mo. 1904 35 J. William Beckmann, New York, N Y N. M. Freund, St. Louis 1903 22 1923 51 1902 23 Oliver Abel, Jr., St. Louis 1901 21 James Barrett Brown, St. Louis Walter C. G. Kirchner, St. Louis William G. Becke, St. Louis 1900 2 Charles Teel, Bellingham, Wash. 1899 44 J. W. Thompson, St. Louis R. O. Raymond, Flagstaff, Ariz. Clair O. Vingom, Madison, Wise. Selden Spencer, St. Louis 1922 44 1898 41 F. E. Sultzman, Hannibal, Mo. J. G. W. Fischer, Alma, Mo. !921 43 1897 34, Oscar C. Zink, St. Louis Theodore Greiner, St. Louis 1920 39 1896 30 Warren H. Cole, Chicago, 111. 1895 28 Alfred Goldman, St. Louis 1894. 15 Samuel B. Grant, St. Louis 1893 17 Frederick E. Jostes, St. Louis 1892 4 L. J. Owen, Lincoln, Neb. 1891 21 Harvey L. White, St. Louis 1890 " ~7 Herman M. Meyer, St. Louis 1889 14 1888 15 1919 45 Carl 0. Kohlbry, Duluth, Minn. 1887 7 A. B. Raffl, Syracuse, N. Y. 1886 6 Duff S. Allen, St. Louis 1885 8 Otto S. Krebs, St. Louis 1884 9 1918 26 1883 12 1882 J. F. Pessel, Trenton, N. J. 2 Glover H. Copher, St. Louis 1881 ZZ.ZZZ 4 James A. Dickson, St. Louis 1917- 25 1880 2 1916 13 1879 ZZZZ 5 Ray T. Woolsey, Salt Lake City, Utah Earl C. Sage, Omaha, Neb. GIFTS FROM PARENTS OF FORMER AND PRESENT STUDENTS 1915 22 Dr. Joseph C. Peden, Sr. D. K. Rose, St. Louis Dr. Lawrence T. Post MEDICAL ALUMNI QUARTERLY 129

Contributors According to Trade Areas Names in italics denote area chairmen. No. of Graduates No. of Graduates Trading Area Center in Trading Area Trading Area Center in Trading Area Albany (N. Y.) 3 Des Moines (la.) 30 Albuquerque (N. Mex.) 5 R. J. Tidrick, Iowa City, la. 33 Amarillo (Tex.) - -> Detroit (Mich.) Orra Hand, Lubbock, Tex. Fred J. Hodges, Ann Arbor, Mich. 9 William A. Hudson, Detroit Atlanta (Ga.) 3 William G. Hamm, Atlanta, Ga. Duluth (Minn.) Baltimore, (Md.) 14 C. O. Kohlbry, Duluth William G. Reese, Perry Point, Md. Carl O. Kohlbry, Duluth, Minn. Birmingham (Ala.) 32 El Paso (Tex.) - 5 Wesley C. Corson, Tuscaloosa, Ala. G. A. Slusser, Silver City, N. M. Bismarck (N. D.) 1 Evansville (Ind.) 22 Boston (Mass.) 26 Willard T. Barnhart, Evansville Walter B. Hoover, Boston, Mass. Frank C. Weber, Olney, 111. Frederick Hagler, Springfield, Mass. Fargo (N. D.) ? Buffalo (N. Y.) 10 Laurence G. Pray, Fargo William L. Bradford, Rochester, N. Y. A. C. Fortney, Fargo, N. D. Butle (Mont.) 4 Grand Rapids (Mich.) 10 Charlotte (N. Car.) - 21 Paul S. Barker, Ann Arbor, Mich. Eugene E. Taylor, Mocksville, N. C. William F. Wenner, Kalamazoo, Mich. 94 Edna Schrick, Holland, Mich. Chicago (111.) Minas Joannides, Chicago Great Falls (Mont.) 8 Carl H. Matthey, Davenport, la. James D. Morrison, Billings, Mont. Walter S. Priest, Chicago David T. Berg, Helena, Mont. 18 H. S. Rumerich, Glen Ellyn, 111. Houston (Tex.) Herman H. Wellmerling, Bloomington, 111. Russell J. Blattner, Houston Marie H. Wittier, Elmhurst, 111. Clarence P. Jasperson, Corpus Christi 8 Samuel Brady, Gary, Ind. Indianapolis (Ind.) I Charles G. Clay, Rantoul, 111. T. B. Noble, Indianapolis Warren H. Cole, Chicago, 111. L. A. Malone, Terre Haute, Ind. Elizabeth E. Koppenaal, Elmhurst, 111. Lloyd Rosenbaum, Anderson, Ind. Cincinnati (0.) -- - 16 Jacksonville (Fla.) 2 LevAs G. Herrmann, Cincinnati Kansas City .(Mo.) 190 Charles M. Polan, Huntington, W. Va. /. B. Carlisle, Sedalia, Mo. Cleveland (0.) 22 W. B. Chapman, Joplin, Mo. Michael E. Geraci, Cleveland Donald M. Dowell, Chillicothe, Mo. W. W. Herman, Cleveland, O; B. L. Elliott, Kansas City, Mo. Anthony Piraino, Oberlin, 0. Stephen S. Ellis, Coffeyville, Kan. Columbus (O.) H Joseph L. Fisher, St. Joseph, Mo. C. C. Sherburne, Columbus Clifford L. Gilles, Kansas City, Mo. Dallas (Tex.) 47 Henry Snyderman, Wadsworth, Kan. Samuel H. Kahn, Dallas Peter 0. Fleming, Topeka, Kan. Albert E. Meisenbach, Jr., Dallas Stephen Ellis, Coffeyville, Kan. Herman. Rice, Temple, Tex. Eugene 0. Parsons, Kansas City, Mo. Terrell Covington, Jr., McKinney, Texas Willard C. Schwartz, Manhattan, Kan. Denver (Colo.) 58 O. Earl Whitsell, St. Joseph, Mo. Col. James H. Forsee, Denver Vincent Williams, Kansas City, Mo. Howard H. Heuston, Boulder, Colo. Louis Kovitz, Kansas City, Mo. J. G. W. Fischer, Alma, Mo. Harvey S. Rusk, Pueblo, Colo. 4 Leonard J. Wiedershine, Cheyenne, Wyo. Knoxville (Tenn.) 130 WASHINGTON UNIVERSITY

No. of Graduates No. of Graduates Trading Area Center in Trading Area Trading Area Center in Trading Area Little Rock (Ark.) 22 Sydney S. Pearl, Elizabeth, N. J. Jerome S. Levy, Little Rock Philip Rosenblatt, New York, N. Y. Roy F. Baskett, Texarkana, Tex. Oklahoma City (Okla.) 22 Los Angeles (Calif.) 126 George H. Garrison, Oklahoma City Herbert Anderson, Los Angeles Raymond L. Murdoch, Oklahoma City Phillip H. Bassett, Corona Del Mar, Calif. Rowe F. Bisbee, Ada, Okla. Edward A. Blondin, San Diego, Calif. Omaha (Neb.) 15 G. E. Christensen, Los Angeles Miles E. Foster, Jr., Omaha Lawrence K. Gundrum, Los Angeles L. J. Owen, Lincoln, Neb. Elmer N. Liljedahl, Los Angeles L. J. Owen, Lincoln, Neb. Elaine K. Lince, Pasadena, Calif. Earl C. Sage, Omaha, Neb. Alfred G. Henrich, Los Angeles, Calif. Philadelphia (Pa.) 20 Carol H. Rehm, Los Angeles, Calif. Lucius R. Wilson, Philadelphia Louisville (Ky.) 4 Mary Jordan, Ridley Park, Pa. Robert F. Monroe, Louisville, Ky. Phoenix (Ariz.) 14 Memphis (Tenn.) 15 Ben P. Frissell, Phoenix Clinton K. Higgins, Memphis Royal W. Rudolph, Tucson, Ariz. W. A. Ruch, Memphis, Tenn. Louis G. Jekel, Phoenix, Ariz. Miami (Fla.) 5 R. O. Raymond, Flagstaff, Ariz. Samuel J. Roberts, Miami Pittsburgh (Pa.) 10 Milwaukee (Wis.) 35 Russell C. Bond, Wheeling, W. Va. L. 0. Helmes, Oshkosh, Wis. Portland (Me.) 1 Volney B. Hyslop, Madison, Wis. Portland (Ore.) 30 Clair 0. Vingom, Madison, Wis. Frank B. Queen, Portland Minneapolis-St. Paul (Minn.) 26 Willard D. Rowland, Portland, Ore. James L. Benepe, St. Paul Frank B. Queen, Portland, Ore. Clarence G. Ochsner, Wabasha, Minn. Richmond (Va.) 16 Edwin F. Robb, Minneaplois Everett C. Brash, University, Va. Archie D. Skemp, La Crosse, Wis. Martin A. Compton, Richmond, Va. C. A. Good, Rochester, Minn. Salt Lake City (Utah) 51 Gershom J. Thompson, Rochester, Minn. R. P. Roantree, Elko, Nev. Nashville (Tenn.) 8 O. Sundwall, Murray, Utah Llyod C. Miller, Nashville Ray T. Woolsey, Salt Lake City New Orleans (La.) 20 W. R. Merrell, Brigham City, Utah Alton E. W. Ochsner C. O'Neal Rich, Salt Lake City, Utah Ray T. Woolsey, Salt Lake City, Utah Lyman Richardson, New Orleans, La. San Antonio (Tex.) 17 New York City 94 Walter G. Stuck, San Antonio /. William Beckmann, New York City San Francisco (Calif.) 86 Lester J. Evans, Jackson Heights, N. Y. B. F. Dearing, San Francisco Joseph A. Fiorito, New Haven, Conn. D. H. Trowbridge, Jr., Fresno, Calif. Samuel Martin, New York City Heinz E. Cron, San Francisco Walter R. Peterson, Trenton, N. J. Anne T. Goetsch, Berkeley, Calif. Philip Rosenblatt, New York City Charles H. Hecker, Palo Alto, Calif. Frank S. White, Teaneck, N. J. Ernest S. Rogers, San Francisco J. William Beckmann, New York, N. Y. Verne Ross, Stockton, Calif. William Ehrlich, Newark, N. J. William H. Smith, Colfax, Calif. I. W. Leibner, Brooklyn, N. Y. Savannah (Ga.) 4, Nathan R. Kahn, Brooklyn, N. Y. Seattle (Wash.) 4.3 J. F. Pessel, Trenton, N. J. Byron F. Francis, Seattle Minton D. Ritter, Margate City, N. J. Vernon O. Lundmark, Enumclaw, Wash. m ■n

MEDICAL ALUMNI QUARTERLY 131

No. of Graduates No, of Graduates Trading Area Center in Trading Area Trading Area Center Trading Area C. A. Nielsen, Seattle, Wash. Wendell G. Scott Charles Teel, Bellingham, Wash. John Seddon Lawrence M. Wilson, Olympia, Wash. Philip Shahan William H. Gray, Yakima, Wash. Robert M. Smith Horace W. Soper Shreveport (La.) 3 Carl Peter Birk, Decatur, 111. 10 Sioux City (la.) Eldon C. Bohrer, West Plains, Mo. Bernard S. Clark, Spearfish, N. D. Alva Trueblood, Jr. 24 Spokane (Wash.) Ray D. Williams Austin, C. Taylor, Spokane Frederic E. Woodruff Syracuse (N. Y.) 5 George J. Wulff John E. Wallenberg, Cortland, N. Y. Oscar C. Zink Arthur B. Raffl, Syracuse, N. Y. James M. Baker, Columbia, Mo. Henry N. Reid, Rome, N. Y. F. Biggs, Jr., Neelyville, Mo. St. Louis (Mo.) 970 Urban J. Busiek, Springfield, Mo. Oliver Abel, Jr. Henry B. Delicate, Edwardsville, 111. Louis Aitken James J. Donahue, E. St. Louis, III. Duff S. Allen George Drennan, Jacksonville, 111. Millard Arbuckle Ben Fox, Carbon dale, 111. Walter Baumgarten, Jr. Edgar H. Keys, Quincy, 111. Grace Bergner W. F. Rose, Dupo, 111. C. Read Boles E. C. Schmidtke, Columbia, Mo. Eugene M. Bricker William E. Stone, Boonville, Mo. Robert Brookes Francis E. Sultzman, Hannibal, Mo. T. K. Brown Oliver Abel, Jr., St. Louis Stanley S. Burns Helen M. Aff, St. Louis Delevan Calkins A. N. Arneson, St. Louis Marshall B. Conrad James W. Bagby, St. Louis Glover Copher James M. Baker, Columbia, Mo. James B. Costen Alfred K. Baur, St. Louis Robert J. Crossen William G. Becke, St. Louis Frank L. Davis Sim F. Beam, St. Louis Charles Duden Donald S. Bottom, Alton, 111. Gladden Elliott Eugene M. Bricker, St. Louis Walter Fischel Raymond M. Charnas, St. Louis William Gaunt Justin J. Cordonnier, St. Louis Samuel B. Grant Russell J. Crider, St. Charles, Mo. R. B. H. Gradwohl F. R. Crouch, Farmington, Mo. Theodore Greiner Robert J. Crossen, St. Louis H. M. Denny, Union, Mo. Guerdan Hardy Stanley Harrison James A. Dickson, St. Louis John Homer James J. Donohue, E. St. Louis, 111. Max Deutch, St. Louis Scott Heuer Bruce Kenamore Norman W. Drey, St. Louis Martin F. Kouri Walter Fischel, St. Louis Everett Lerwick I. J. Fiance, St. Louis Guy Magness N. M. Freund, St. Louis Frank P. McNalley David Friedman, Granite City, 111. Joseph M. Noah Herbert H. Gass, St. Louis David R. Oliver Alfred Goldman, St. Louis David L. Penney Melvin L. Goldman, St. Louis G. D. Royston Leo Gottlieb, St. Louis Otto H. Schwarz Samuel B. Grant, St. Louis 132 WASHINGTON UNIVERSITY

No. of Graduates No. of Graduates Trading Area Center in Trading Area Trading Area Center in Trading Area Theodore Greiner, St. Louis Edwin C. Ernst, St. Louis Carl G. Harford, St. Louis A. H. Hutto, St. Louis Stanley Hampton, St. Louis Richard K. Kimmel, St. Louis Walter C. G. Kirchner, St. Louis H. R. Hildreth, St. Louis S. P. Martin, East Prairie, Mo. J. T. Jean, St. Louis Frank McDowell, St. Louis John Johnstone, Jr., St. Louis Melvin A. Roblee St. Louis Frederick E. Jostes, St. Louis Tampa (Fla.) 8 Joseph C. Jaudon, St. Louis Frances C. Wilson, Tampa Bruce Kenamore, St. Louis Roscoe Maxwell, Punta Gorda, Fla. Robert E. Koch, St. Louis Toledo (0.) 4 William B. Kountz, St. Louis Edward L. Burns, Toledo G. Bruce Lemmon, Springfield, Mo. Edward Massie, St. Louis Tulsa (Okla.) 39 Harold E. McCann, E. St. Louis, 111. W. A. Showman, Tulsa Washington, D. C 30 Gordon F. Moore, Alton, 111. Gordon S. Letterman Carl V. Moore, St. Louis Col. Paul I. Robinson I. D. Newmark, Chester, 111. Harlan I. Firminger, Bethesda, Md. Mary Louise Newman, Jacksonville, 111. R. A. Nussbaum, St. Louis Wichita (Kan.) 34 John F. Patton, St. Louis Wilbur G. Gillette, Wichita Burnet W. Peden, St. Louis Outside United States 34 Virginia H. Peden, St. Louis H. M. Chandler, Waipahu, T. H. A. Victor Reese, St. Louis R. D. Kepner, Honolulu, T. H. Edward H. Reinhard, St. Louis Eichi Masunaga, Hawaii Wendell G. Scott, St. Louis Richard Y. Sakimoto, Honlulu, T. H. Ben H. Senturia, St. Louis Kazuo Miyamoto, Honolulu, T. H. Jay Marvin Salzman, Springfield, 111. James W. Owen, Jr., Guam, M. I. Carvel T. Shaw, Hermann, Mo. Frank Vellios, Guam, M. I. Selden Spencer, St. Louis Sam R. Wallis, Kauai, T. H. F. E. Sultzman, Hannibal, Mo. Frances H. Stewart, St. Louis J. W. Thompson, St. Louis Postgraduate Courses Barrett L. Taussig, St. Louis Offered for Winter Louis L. Tureen, St. Louis A one-week course in clinical allergy, Helman C. Wasserman, St. Louis Harvey L. White, St. Louis planned specifically for the general W. B. Wilcoxen, Bowling Green, Mo. practitioner, will be given from Novem- Oscar C. Zink, St. Louis ber 7 to 11 by the Division of Post- Dorothy J. Jones, St. Louis Morris D. Marcus, St. Louis graduate Studies at the Medical School. Clover H. Copher, St. Louis A short course from December 1 to 3 Joseph W. Noah, St. Louis will explain the newer aspects and de- Herman M. Meyer, St. Louis D. K. Rose, St. Louis velopments of medical technology to Seymour Brown, St. Louis laboratory technicians. Duff S. Allen, St. Louis Delevan Calkins, St. Louis Complete information on these two Otto S. Krebs, St. Louis courses may be obtained by writing to Omar Sevin, St. Louis the Division of Postgraduate Studies in James Barrett Brown, St. Louis Louis T. Byars, St. Louis care of the School of Medicine. MEDICAL ALUMNI QUARTERLY 133 FACULTY CHANGES AND APPOINTMENTS

The following changes and appoint- Robert J. Glaser, Robert Paine pro- ments to the faculty of the School of moted to instructors in medicine; Ben- Medicine became effective on July 1 in jamin H. Charles, I. J. Fiance, Joseph the various departments: W. Noah, Ernest T. Rouse, Milton Smith, Robert M. Smith, Franz Stein- Anatomy berg, J. Harrison Wedig promoted to John C. Finerty promoted to associate instructors in clinical medicine. professor; Albert I. Lansing promoted Helen E. Clark, William A. Clay, Joe to associate professor; Edward L. Kuff Bill Hall, Norman P. Knowlton, Frank promoted to instructor; Morris Alex ap- B. Norbury, John K. Spitznagel, David pointed research assistant; Mr. Donald W. Talmage, Clifford Tillman appointed L. Opdyke appointed research fellow. assistants in medicine; Jack Barrow, John W. Berry, Albert B. Eisenstein, Bacteriology and Immunology Frank F. Martin, Hugh B. Waters ap- Samuel J. Ajl appointed assistant pro- pointed clinical fellows in general med- fessor; Frank L. Adler appointed assis- icine; Arthur L. Gropper appointed fel- tant (effective September 1). low in hypertension; Bernard S. Lipman appointed fellow in clinical cardiology; Biological Chemistry Virgil Loeb, Jr., John B. Shapleigh II Maurice E. Krahl promoted to asso- appointed fellows in clinical hematol- ciate professor. ogy; Seymour Reichlin appointed fel- Medicine low in clinical metabolism. Warren P. Elmer, status changed to Neuropsychiatry associate professor emeritus of clinical medicine; Walter Fischel promoted to Margaret C.-L. Gildea and Sydney B. associate professor and retired with title Maughs promoted to assistant professors of associate professor emeritus of clin- of clinical psychiatry; Joseph Gitt pro- ical medicine. moted to assistant professor of clinical Gustave J. Dammin promoted to asso- neurology; Frank R. L. Egloff, Arthur ciate professor of medicine and pathol- S. Greditzer, Wanda Lamb, Joseph M. olgy; Carl G. Harford, Edward H. Rein- Natterson, Patricia L. O'Neal appointed hard and John R. Smith promoted to assistants; Eli Robins appointed U.S. associate professors; Samuel C. Bukantz P.H.S. fellow in psychiatry and in phar- promoted to assistant professor; Arthur macology (effective September 1) ; C. Brooks and Bruce Kenamore pro- Shirley J. Shaffer appointed fellow in moted to assistant professors of clinical psychiatry; Robert R. Lam appointed fellow in neurology. medicine. 134 WASHINGTON UNIVERSITY

Obstetrics and Gynecology structor in pediatrics and in child psy- William H. Masters promoted to as- chiatry and assistant director of the sistant professor; Ralph B. Woolf pro- Child Guidance Clinic; John Holland moted to instructor; John L. Cockrell. appointed dentist in pediatrics; C. Read Frank B. Long, Wallace R. Stacey ap- Boles, Frank Wissmath appointed assis- pointed assistants; Bryce Bondurant, tant in clinical pediatrics; Rosellen MacDonald Bonebrake, Donald W. Rob- Cohnberg, Marvin Cornblath, William inson appointed fellows. Daeschner, Oliver F. Deen, Jr., Robert Garner, Helen Hofsommer, James Mc- Ophthalmology Neil, Sterling Suddarth appointed as- Harold Beasley appointed assistant in sistants. clinical ophthalmology; Justine Sleight appointed assistant. Preventive Medicine and Public Health Otolaryngology Herbert R. Domke appointed assistant Isaac D. Kelley promoted to associ- professor of public health; Albert I. ate professor of clinical otolaryngol- Mendeloff appointed assistant profes- ogy; William F. Andrew, Jose A. Bello, sor of preventive medicine and of medi- Cecil S. Franks, Robert W. Hazen, cine and physician to students at the George T. Hodges, Charles C. Jacobs, Medical Center. Watson B. Larkin, Joseph J. Littell, Joseph W. West appointed assistants; Pharmacology Chiang Tung-Ming appointed fellow. Morris Friedkin appointed instructor in pharmacology (effective October 1) ; Pathology Jack L. Strominger appointed American Franz Leidler, Thomas L. Young pro- College of Physicians Research Fellow moted to instructors; Frank L. Beckel, in Pharmacology. appointed instructor; James C. Hawk- ins, Menard Ihnen, James C. Roberts, Radiology Dale M. Schulz, William Snoddy ap- Sherwood Moore status changed to pointed assistants; Raymond F. Hain professor emeritus of radiology; Hugh appointed fellow; Louis T. Litzow ap- M. Wilson, appointed professor of ra- pointed fellow in surgical pathology. diology and director of the Mallinckrodt Institute of Radiology; William B. Sea- Pediatrics man appointed instructor; Wesley Fee, Adrien S. Bleyer, status changed to Thomas Keely, A. Jack Stacy appointed associate professor emeritus of clinical assistants in radiology. pediatrics. Joseph A. Bauer, Maurice J. Lonsway Surgery promoted to instructors in clinical pe- Leo. A. Sachar promoted to instructor diatrics; Dorothy Case appointed in- in clinical surgery; William E. Hunt, MEDICAL ALUMNI QUARTERLY 135

Darrell Munro, Harrison H. Shoulders, instructor in clinical dermatology; Ar- Hugh E. Stephenson, Jr., William B. nold H. Williams promoted to instructor Wall, Jr., appointed assistants; Harvey in physiology in medicine; Miss Beat- R. Bernard, Edward J. Bishop, M. Rich- rice Schulz appointed instructor in ard Carten, William F. Collins, Fleming physical therapy; Mr. Jesse B. Lasater B. Harper, Bart F. Wooldridge ap- appointed lecturer in vital statistics; pointed fellows in general surgery; Hal Mr. Elmer P. Wheeler appointed lec- B. Jennings appointed fellow in plastic turer in industrial hygiene; Miss Mar- surgery; Thomas G. Otto appointed fel- guerite Cannon appointed assistant in low in orthopedic surgery; James L. psychiatric social work; Lilli Hofstatter Schricker, Jr., appointed fellow in appointed research assistant in gerontol- neurosurgery; Frederick H. Taylor ap- ogy; Crofford Vermillion appointed as- pointed fellow in thoracic surgery. sistant in hospital administration; E. Praetorius appointed fellow in geron- Miscellaneous tology; Donald Stewart appointed fel- Adolph H. Conrad, Jr., promoted to low in chest diseases.

DEPARTMENTAL NEWS Auxiliary Medical Services Bacteriology Among those receiving degrees on Dr. Alfred D. Hershey, associate pro- June 7 from Washington University fessor of bacteriology and immunology, were 11 students in occupational ther- attended a conference sponsored by the apy and 11 in hospital administration. National Academy of Science at Shelter Miss Sue P. Hurt, director of Occupa- Island for the discussion of current tional Therapy, reported that 13 stu- developments and trends in studies of dents completed their academic work the gene. He attended meetings of the and went into clinical training in July. Society of American Bacteriologists in They will be candidates for degrees in Cincinnati, May 17-20, and participated June, 1950. Dr. Frank R. Bradley '28, in a round table discussion on nucleic professor of hospital administration, an- acids. His topic was "Relation of Nu- nounced that 12 students in his depart- cleic Acids to Bacterial Genetics." ment completed their first year of aca- Medicine demic training and went into intern- ships. Dr. Sedgwick Mead, assistant pro- Dr. Joseph C. Edwards presented a fessor of physical medicine, reported paper on the "Evaluation of Anterior that eight students in physical therapy Pituitary Extracts in the Treatment of will finish their clinical training in Pituitary Dwarfism" at a meeting of the October. Four of these will be candi- Association for the Study of Internal dates for B.S. degrees next year and the Secretions in Atlantic City June 3. Dur- remaining four will receive certificates. ing the first week in June, he attended 1.36 WASHINGTON UNIVERSITY

meetings of the American Heart Asso- Otolaryngology at Bloomington, Ind., ciation and its Scientific Council, and on May 4 and 5. He spoke on treatment the American Diabetes Association. of external diseases of the eyes and took Dr. Richard S. Weiss '09 was elected part in a round table discussion with vice-president of the American Derma- Dr. 0. E. Van Alyea on the relationship tological Association during a meeting between disorders of the eyes and the of the group in Hot Springs, Va., late nasal sinuses. in May. Dr. Richard G. Scobee, assistant pro- Neuropsychiatry fessor, was one of the guest speakers at At the meeting of the Midwestern a symposium on the muscles of the eye Psychological Association in Chicago, at the University of Iowa during the during April, four members of the Divi- week of May 23. sion of Medical Psychology were in at- Dr. Lawrence T. Post, professor of tendance. They were Dr. Robert I. Wat- clinical ophthalmology, and Dr. Rich- son, Dr. Saul Rosenzweig, Dr. Ivan ard Scobee attended the annual meeting Mensh, and Mrs. Betty Caldwell. In col- of the American Ophthalmological So- laboration with Dr. Philip H. Du Bois ciety in Hot Springs, Va., June 2 to 5. of the Department of Psychology at the University, Dr. Watson gave a paper on Otolaryngology the selection of patrolmen for the St. Twenty-four students completed the Louis Police Department. He and Dr. eight-month postgraduate course in the Rosenzweig served as chairmen at sec- Department of Otolaryngology on May tion meetings concerned with clinical 20. problems. Dr. Ivan Mensh gave a paper Pathology on psychological similarities in folie a Dr. Robert A. Moore, Dean and pro- deux. fessor of pathology, attended meetings Dr. Edwin F. Gildea, professor of of the National Board of Medical Exam- psychiatry; Dr. George Saslow, associ- iners in Atlantic City on June 14, and ate professor of psychiatry; Dr. Sydney the Advisory Committee on Cancer Con- B. Maughs, instructor in clinical psy- trol of the U. S. Public Health Service chiatry; and Dr. Frank 0. Shobe, fellow in Washington, D. C, immediately in psychiatry, attended the annual meet- afterwards. ing of the American Phychiatric Asso- ciation in Montreal, Canada, the week Pediatrics of May 23. The Idaho State Medical Association, meeting at Sun Valley from June 20 to Ophthalmology 23, had as one of its guest speakers Dr. Dr. Bennett Y. Alvis, associate pro- Alexis F. Hartmann '21, professor of fessor of clinical ophthalmology, was pediatrics. He spoke on the fundamen- guest of honor at a meeting of the In- tals of electrolyte and water and carbo- diana Academy of Ophthalmology and hydrate metabolism and their appli- MEDICAL ALUMNI QUARTERLY 137 nj cation in the prevention and treatment Surgery of acidosis and alkalosis and in the rec- Dr. Justin J. Cordonnier '28, was i; ognition and treatment of hypoglycemia awarded first prize for his exhibit in and diabetes mellitus. Clinical Investigation in the Scientific Exhibit Section of the American Uro- Pharmacology logic Association meeting in Los An- Dr. and Mrs. F. E. Hunter left June geles in May. 15 for a European visit during which The American College of Chest Phy- Dr. Hunter will stop at scientific labora- sicians presented its gold medal award tories in France, Switzerland, Belgium, to Dr. Evarts A. Graham, Bixby Pro- Holland, Denmark, Sweden, Norway, fessor of Surgery, on June 4 during a and England. He will attend the Inter- meeting of the group in Atlantic City. national Congress of Biochemistry Dr. James Barrett Brown '23, profes- which meets at Cambridge, England, sor of clinical surgery, lectured at the from August 19 to 25. University of Oklahoma May 12 on car- cinoma of the mouth and jaws, and at Preventive Medicine Northwestern University on June 6 on Dr. George M. Saunders, assistant the management of tumors of the mouth, professor of preventive medicine, dis- face, and jaws. cussed bacteriology, public health, para- Dr. John F. Patton '28, assistant pro- sitology, and entomology during a Sci- fessor of clinical genito-urinary surgery, ence Career Day sponsored by the Mis- was elected to membership in the Amer- souri and St. Louis Junior Academies of ican Association of Genito-Urinary Sur- Science in St. Louis during April. geons, which limits its number to 75, at Radiology the m§eting in White Sulphur Springs, W. Va. Dr. Martin D. Kamen, chemist to the Mallinckrodt Institute of Radiology, has Dr. Robert W. Bartlett, assistant pro- been appointed a member of the Na- fessor of clinical surgery, was elected tional Research Council Committee on to membership in the American Goiter Radiology and a member of the subcom- Association at the annual meeting held mittee planning an international sym- in Madison, Wis., May 26 to 28. posium on the basic aspects of inter- Dr. Robert Elman, professor of clin- action of radiation with biological sys- ical surgery, discussed a paper on acute tems. pancreatitis at the A.M.A. meeting in The A. M. A. Silver Medal was Atlantic City in June, and immediately awarded to Dr. Wendell G. Scott '32, following that attended a meeting of the Dr. Merl J. Carson of the Department National Professional Advisory Com- of Pediatrics, Dr. Thomas H. Burford mittee in Washington, D. C. Dr. Elman of the Department of Surgery, and Dr. gave the Max Ballin Lecture in Detroit Sherwood Moore '05, for the exhibit of on May 4, speaking on starvation in gen- the Rapidograph. eral practice. 138 WASHINGTON UNIVERSITY Publications of the Faculty April - June, 1949

Alexander, H. L., Grunow, 0. H. W. & Smith, J. R. Rheumatic heart disease with Gi respiratory failure. Clinico-pathologic conference. Am. J. Med. 6: 781-789. June, 1949. Andrew, W. Age changes in the salivary glands of Wistar institute rats with particu- lar reference to submandibular glands. J. Gerontol. 4: 95-103. April, 1949. Breakey, M. R. & Davis H. Comparisons of thresholds for speech: word and sentence tests, receiver vs. field, and monaural vs. binaural listening. Laryngoscope 59: 236- 250. March, 1949. Briseno-Castrejon, B. & Finerty, J. C. An azocarmine stain for differential cell analysis of the rat anterior hypophysis. Stain technol. 24: 103-107. April, 1949. Brown, J. B. Repair of radiation burns. Proc. Inst. Med. Chicago 17: 330-331. May 15, 1949. Brown, J. B., Fryer, M. P. & McDowell, F. Internal wire-pin immobilization of jaw fractures. Plastic and reconstruct, surg. 4: 30-35. January, 1949. Brown, J. B„ McDowell, F. & Fryer, M. P. Surgical treatment of radiation burns. Surg. G-yn. Obst. 88: 609-622. May, 1949. Burford, T. H. Surgery of congenital cardiovascular lesions (Abstr.) Weekly Bull. St. Louis Med. Soc. 43: 460-461. May 27, 1949. Carson, M. J. Diagnostics and clinical asthenics (Abstract). Weekly Bull. St. Louis i Med. Soc. 43: 457. May 27, 1949. Chieffi, M. & Kirk, E. Chronaxie studies in thiamine-deficient old individuals. J. Gerontol. /,; 127-131. April, 1949. Cordonnier, J. J. Ureterosigmoid anastomosis. Surg. Gyn. & Obstetrics 88: 441-446 April, 1949. Costello, C. & McDonald, J. The role of a new analgesic in surgery. J. Mo State Med Assn. 46: 333-337. May, 1949. Cowdry, E. V. Epidermal carcinogenesis. Acta unio internat. contra cancrum. 6: 3-8 1948. Davis, H. The Forbes "School" of neurophysiology at Harvard. Electroencephalography and clin. neurophysiol. 1: 139-140. May, 1949. Delarue, N. C. & Graham, E. A. Alveolar cell carcinoma of the lung (pulmonary adenomatosis, Jagziekte?) A multicentric tumor of epithelial origin J thorac sure 18: 237-251. April, 1949. s' Dubach, R., Moore, C. V. and Callender, S. Iron excretion in human subjects as measured by the isotope technique. Fed. Proc. 8: 353. March, 1949. Elam, J. O., Ehrenhaft, J. L., Elam, W. N., Jr. & White, H. L. Photo-electric measure- ments of the arterial 02 saturation dynamics in man for study of cardiopulmonarv function. Fed. Proc. 8: 40. March, 1949. Elman, R. Surgical forum. Arch. Surg. 58: 539-540, April, 1949. Elman, R. & Lemmer, R. A. The pancreas; contributions' of clinical interest made in 1947. Gastroenterology 12: 375-390. March, 1949. Fields, W. S. Tularemic meningitis, report of a case. Arch, neurol. & psvchiat 61 ■ 422-429, April, 1949. Fields, W. S., King, R. B. & O'Leary, J. L. Study of multiplied cortical response to repetitive stimulation in thalamus. J. Neurophysiol. 12: 117-130. March 1949 Finerty, J. C. & Briseno-Castrejon, B. Quantitative studies of cell types'in the rat , hypophysis following unilateral adrenalectomy. Endrocinol. 44: 293-300. April,. 1949 Ford, L. T. The diagnosis of lesions of the lumbar intervertebral discs (Abstract > Weekly Bull. St. Louis Med. Soc. 43: 475-477. June 3, 1949. ^osiracr.; Gentry, J. T. The malignant cell in an environment of normal cellular constituents- selective specificity in a replacement approach to cancer and related problems Amer naturalist 82: 118-128, March, April, 1948. Piouiems. Amer. Gernandt, B E Riesco-McClure, J. S., &. Davis, H. Biophysics of the cochlea. Fed Proc. 8: 56, March, 1949. Gest H. & Kamen, M. D. Photoproduction of molecular hydrogen by Rhodosnirillum rubrum. Science 109: 558-559. June 3, 1949. ^.noaospiruium Gibbs, R. P. & Stowell, R. E. Glycogen in human blood cells. Blood 4: 569-579. May, MEDICAL ALUMNI QUARTERLY 139

Graham, E. A. The first total pneumonectomy. Texas Cancer Bull. 2: 2-4, January- Grins™k19f Moore, C. V. Studies in iron transportation and ^M^Jg; Evidence obtained with radioactive iron that "easily split-ofl blood iron is an artefact J clin. invest. 28: 505-515. May, 1949. IrinsfeS' M, Kamen, M. D„ Moore, C. V. The utilization of glycme in the biosyn- thesis of hemoglobin. J. biol. chem. 179: 359-364. May, 1949. Hanse F K The treatment of headache, with particular reference to the use of cafergone (ergotamine tartrate and caffeine) for the relief of attacks. Ann. Allergy 7 • 155-161. March-April, 1949. . _. Hawker, W. D. & Allen, M. A study of 145 consecutive twin pregnancies. Am. J.T Obst.t He^S'f'DSati^o/polysaccharides by muscle phosphorylase. Fed. Proc. 8: He^ri^1!™ Fermentation of disaccharides. II Sucrose. Wallerstein lab. comm. 12: Hunter, Tt, T Anaerobic phosphorylation due to a coupled oxidation-reduction between a-ketoglutaric acid and a-immoglutaric add Fed Proc. 8 208. March 1949. Jayne, E. P. Age pigments in human cardiac muscle. (Abstr.) Anat. Rec. 103. ill 4/d. KamenhM9D' & Gest, H. Evidence for a nitrogenase system in the photosynthetic bacterum Rhodospirillum rubrum. Science 109: 560. June 3, 1949. Kamen MD Kennedy, J. W. & Myers, 0. E. Kinetics studies on isotopic exchange reactions with some remarks on their relevance in classification of types of chemical bonding In Echanges isotopiques et structure moleculaire, Paris, Avnl, 1948. KameJV D. & Spiegelman, S. Studies on the phosphate metabolism of some uni- cellular orgknisms. Cold Spring Harbor symposia on quantitative biology. 13: 151- Keller P D & Nute W L., Jr. Cirrhosis of the liver in children; a clinical and patho- logical'study of forty cases. J. pediat. 34: 588-615, May, 1949 Key J A. The intervertebral disc: conservative treatment. (Abstr.) Weekly Bull. St. Louis Med. Soc. i3: 471. June 3, 1949. Keyes E. L. & Rindskopf, W. What are the common types of cancer? J. Mo. State med'. assn. >t6: 356. May, 1949. Kirk E. The urinary excretion of neutral 17-ketosteroids in middle-aged and old men. J. Gerontol. It: 34-38, January, 1949. Kountz, W. B., Chieffi, M. & Kirk, E. Serum protein-bound iodine and age. J. Gerontol. /,: 132-135. April, 1949. Kvornin- S A & Kirk, E. The correlation between the clinical appearance of the skin and the skin lipid secretion in middle-aged and old individuals. J. Gerontol. J,: 113- 120 April 1949. Kvorning, S.A. & Kirk, E. The serum silica concentration at various ages. J. Gerontol. k: 16-18. January, 1949. . . Loeb, L. Aging processes in the ovaries of mice belonging to strains differing in the incidence of mammary carcinoma. Arch. Path. Ifi: 401-440. Nov., 1948. Manson, L. A. & Lampen, J. O. Enzymatic degradation of thymidine. Fed. Proc. 8: 224. March, 1949. Masters, W. H. Ectopic pregnancy; a report of 106 cases. J. Mo. State Med. Assn. J,6: 405-410. June, 1949. Mead S. Physical treatment of peripheral vascular disease. J. Am. med. assn. 1SJ. 1059-1064. April 16, 1949. Miles P. W. & Dixon, J. M. Tuberous sclerosis in three siblings. Arch. Ophthalmol. 41:' 473-480. April, 1949. Moore M Anderson, W. A. D. & Everett, H. H. Mucormycosis of the large bowel. Am.'j. path. 25: 559-567. May, 1949. Moore, R. A. The medical approach to the problems of aging. J. Gerontol. //: 90-94. April, 1949. Mnnre S Mass roentgenological survey of the gastrointestinal tract to detect cancer of the stomach. Am. j. roentgenol. 61: 470-474. April, 1949. 140 WASHINGTON UNIVERSITY

Neville, J. P., Jr., Elam, J. O., Sugioka, K. & Roos, R. Transmission spectra of the human ear (pinna and lobe) at arterial occlusive pressures. Fed Proc 8- 118 March, 1949. Nuetzel, J. A. & Olsen, N. S. Response to intravenous injection of small quantities of insulin. Fed. Proc. 8: 120. March, 1949. 0d£\ ^ ^" °Perative results in lumbar intervertebral discs (Abstract). Weekly Bull. St. Louis Med. Soc. 43: 473-474. June 3 1949. Paine, R Howard, F. A. Butcher, H. R. & Smith, J. R. Observations on pulmonary lymph flow and edema. Fed. Poc. 8: 123. March, 1949. Pareira M. D & Probstein, J. G. Glucose assimilation during anesthesia and surgery. Ann. Surg. 129: 463-467. April, 1949. P°Ma M1949 Prevention of iniection in eye surgery. Amer. j. ophthal. 32: 679-685. Proud, G. O. N. Hoarseness. J. Mo. State. Med. Assn. 46: 354-356. May 1949 T?n°^' Jo C; 0Pora,tn1T^ technl«ue (Abstract). Weekly Bull. St. Louis Med. Soc. 43: 472-473. June 3, 1949. Reubi, F. C. & Futcher, P. H. The effects of histamine on renal function in hypertensive IE and normotensive subjects. J. clin. invest. 28: 440-446 May 1949 R134 1viarehlai949H' DireCt determination of S&s tensions by blood. Fed. Proc. 8: Rosenzweig S. Kogan, K. L. Psychodiagnosis; an introduction to tests in the clinical practice of psychodynamics. N. Y., Grune, 1949. Blii Sable, HZ. Inhibition of oxidation and phosphorylation in kidney homogenates6 byy yeast adenylic acid. Fed. Proc. 8: 246. March 1949 li': S8J°?wJS ^abri0^KB' W'nt T?^' T' A study of mescaline in human subjects. U J. Pharm. & Exp. Therap. 95: 455-459. April 1949 j Schoepfle, G M. Action potentials of the cerebellar cortex elicited by stimulation of ohvo-cerebellar fibers. Fed. Proc. 8: 140. March 1949 . ^March^^ A' RaPid spontaneous variations in' blood pressure. Fed. Proc. 8: 140. Schroeder H. A., Futcher, P. H. & Goldman, M. L. The effects of the "rice diet" upon 1949 Pressm'e of hypertensive individuals. Ann. Int. Med. 30: 713-732. April, Schroeder, H. A Goldman, M. L., Futcher, P. H. & Hunter, M. Low sodium chloride diets in hypertension. J. Am. Med. Assn. 140: 458-463 June 4 1949 """ride Scobee R. G The problem of the cross-eyed child. Interne. 15: 67 68, 77 March 1949 SC?tA7\G; The ^"graphical techniques using the tautograph and Seraph (Abstr.) Weeklylr bull. St. Louis med. soc. 43: 458-459 May 27 1949 rapmograpil- I Shaffer P. A. [Remarks] Meeting of Society, Tuesday, April 5, 1949 award of gold medal and certificate of merit for 1949, Robert E. Schlueter, Ph.G. M D Week y bull. St. Louis Med. Soc. 43: 489. June 10 1949 ' weeKly Silberberg, R^ & Silberberg, M. Mammary cancer in castrate male mice receiving y S SoC Exp BioL & 5°™ MarchT949 ^ * ^^ ^ ^ " ' Med ™ Sleator, W., Jr., Elam, J. O., Kilian, D. J., Elam, W N Jr nnmnarknr „f t^^o^- ■ spectra of blood in the human ear flushed by MstaminTwX those oh S after heat flushing. Fed. Proc. 8: 147. March, 1949. uuiamea alter Slein, M. W. Phosphomannose isomerase. Fed. Proc. 8: 252 March 1949 S^^rlSodc.lT5lPecrhal[94T9 * & C°ri" °- ^ ACtiVati°n °f P^-Sglucomutase.

' Tayl°2r59J- MafcSTS *' ^ ^^ Weigbt °f human fetal hemoglobin. Fed. Proc. Walker, S. M. Effect of temperature on the response of rat muscle to indirpnt r-orw - stimulation. Fed. Proc. 8: 161. March, 1949. indirect repetitive+ White, H. L., Heinbecker, P. & Rolf, D. Enhancing effect* nf P-™-,,^!, >,~ „ function. Am. J. Physiol. 157: 47-51. April, 1949. g °Wth hormo™ on renal White, H. L., Heinbecker, P. & Rolf, D. Further observations ™ +h ^ renal function following hypophysectomy. C. FhylJol 156• 67 78 T^^To^ Wiame, J. M. The occurrence and physiological behavior of two SLh ^ 949' tions in yeast. J. Biol. Chem. 178: 919-929 April 1949 metaphosphate frac- MEDICAL ALUMNI QUARTERLY 141

Wiener M Surgery of the eye. ed. 2. N. Y., Grune, 1949. Williams, A. H. Pressure and flow of blood distal to a point of reduced arterial bore. Fed Pi'oe. 8: 166. March, 1949. Wood W B Jr Defense mechanisms of the host in relation to chemotherapy of acute bacterial infections. In MacLeod, C. M., ed. Evaluation of chemotherapeutic agents, symposium held at the New York Academy of medicine, March 25-26, 1948. N. Y., Columbia Univ. press, 1949. itlij Wood W B Jr Greaves, D. & Shank, R. E. Clinico-pathologic conference—anorexia, weakness/prostration and death. Am. J. Med. 6: 495-503, April, 1949.

Alumni News

1895 Delegates at ten conventions, and has On April 5, 1949, the St. Louis Medical been re-elected to represent it in 1949, Society awarded its Certificate of Merit 1950, and 1951. He is a diplomate of the and Gold Medal to Robert E.Schlueter"in American Board of Surgery, Founders' recognition of his distinguished service to Group, and holds membership in the medicine, his scholarly contributions to American College of Surgeons and many medical history, to this Society and to its other professional and scientific groups. Library." Dr. Schlueter, who was born in Dr. Schlueter is held in high esteem by St. Louis on June 9, 1872, was graduated historians for his many contributions to cum laude from the Missouri Medical medical history, and for his contribution College and won the Charles 0. Curtman to the development of the library of the prize in chemistry at that time. After St. Louis Medical Society. The Society graduation he taught in physiology and appointed him honorary librarian for life pharmacy at his Alma Mater, and three recently. years later was appointed instructor in Dr. J. William Thompson '23, president surgery at Washington University, a posi- of the St. Louis Medical Society, pre- tion which he held until 1916. Since 1923 sented the medal and certificate to Dr. he has been associate professor of sur- Schlueter. Honoring him on the occa- gery at St. Louis University School of sion were Dr. Philip A. Shaffer, distin- guished service professor of biological Medicine. In 1909 and 1910, Dr. Schlueter spent chemistry in the School of Medicine; Dr. m his time in postgraduate study under the Chauncey D. Leake, vice-president in great men of that time in the medical charge of medical affairs at the Univer- centers of Europe. Upon his return to sity of Texas; and Dr. R. Emmet Kane St. Louis, he became one of the leading '99, St. Louis physician and former presi- surgeons, with appointments on the staffs dent of the Medical Society. of several hospitals in the city. He emerged from World War I as a major, 1901 and since 1944 has been consultant to R. E. Holben wrote a recent note to the the Army Medical Library in Washington. Quarterly telling of his retirement from Dr. Schlueter has received many honors the staff of the Jacksonville (Til.) State from local, state, and national medical Hospital when he reached the retirement societies. He was president of the St. age of 70. But Dr. Holben was not ready Louis Medical Society in 1911, of the Mis- to retire, so he has stepped across the souri State Medical Association in 1918, state border into Iowa where he is senior and of the St. Louis Surgical Society in house physician at the Mount Pleasant 1941. He has represented the Missouri State Hospital in Mount Pleasant. State Association in the A.M.A. House of The April issue of the Quarterly erro- 142 WASHINGTON UNIVERSITY

neously reported that John E. Lion- months on furlough and has been study- berger was in South Bend, Ind. Dr. Lion- ing recent developments in medicine. berger is living in St. Louis at 5260 During his 17 years as a medical mis- Westminster Ave., and his son, John R. sionary in India, he has made many con- Lionberger, Jr., who graduated from the tributions to the treatment of leprosy School of Medicine in 1938, is practicing and received recognition from the Indian in South Bend. Government for meritorious service in 1903 this field. Dr. Gass was born in India, the F. IV. Gordon now lives at 432 N. Willow son of missionaries of the Evangelical Ave., in Fayetteville, Ark. and Reformed Church, and plans to re- turn shortly. 1909 1931 William H. Thaler has moved from St. Don C. Robertson can be reached at Louis to Long Beach, Calif., where he is 1202 S. Kuhl in Orlando, Fla. living at 464 Cowles Street. 1933 1917 Richard B. Fnlks wrote a letter to tell Wilbur K. Brown visited the Alumni of his change of address to the State Office in June, with Frank P. McNalley Bank Building in California, Mo. He serving as his guide during a visit to wrote as follows: "For the alumni rec- St. Louis. Dr. Brown practiced in East ords—I have returned to my home town St. Louis until 1921 and after a year's for general practice, having opened my training in eye, ear, nose and throat office here on June 6. I have spent a specialty at New York Postgraduate Med- number of years in Kentucky in general ical School, moved to San Diego. He prac- practice and in connection with the Ken- ticed in San Diego until a year ago when tucky State Department of Health, as he retired, but still lives there at 3795 health officer, later as Director of the Highland Avenue. Dr. Brown has three Division of County Health Work, and for sons, age 26, 24, and 22, all of whom a brief period as Acting State Health served in the recent war. He is especially Commissioner. proud of one son who received the Silver "During the period of my service with Star Medal for valor on the Siegfried Line the Kentucky State Health Department, as a staff sergeant on Patton's line. Dr. I spent one year at Columbia University Brown was happy to be able to contradict in postgraduate study leading to the de- a report that he had passed on, which gree of Master of Public Health. I am Dr. McNalley had heard somewhere. happy to be back in Missouri, and I am looking forward to resuming contact with 1919 the School and to seeing friends and asso- Edward H. Hashinger has new offices ciates of my school years." in the Plaza Time Building at 411 Ala- meda Rd. in Kansas City 2, Mo. 1935 Henry J. Lane moved recently to 1516 1923 Edgewood Drive in Palo Alto, Calif. Harold F. Corson recently moved from Richmond, Va., to 604 Monticello Drive, 193€ Jefferson Village Apartments, Falls Arthur C. Barrow's home address is Church, Va. 14249 Tyler Road, San Fernando, Calif. 1930 0. Elliott Ursin, who is now a colonel, Herbert H. Glass, medical missionary is with the Surgeon's Office, Headquarters' from Baitalpur-Chandkuri, C. P., India, First Army at Governor's Island in New has been in St. Louis for the past several York Citv. MEDICAL ALUMNI QUARTERLY 143

Robert Dunn is at the U. S. Marine at 12103 Ventura Place in Studio City, Hospital in Baltimore, Md. Calif. His practice is in allergy. Robert Anschuetz is in private practice 1937 in Alton, 111., with offices at 412 Bluff St. It. Col. Martin A. Compton has moved to Richmond, Va., where he is with the 1941 R. 0. T. C. unit of the Medical College Gordon Letterman, recently on the sur- of Virginia. gical staff at Barnes Hospital, is no\» in Edward H. Lyman is living at 5960 De Washington, D. C, where he can be Giverville Ave. in St. Louis. reached at 2019 R Street, N. W. The address of Edwin L. McCall is 9012 Manchester Rd., in St. Louis County, Mo. 1942 Charles E. Martin is also in St. Louis The Forty-Five Hundred West Pine and has his office at 3911 Lee Ave. Clinics Psychiatric Unit in St. Louis an- Edward A. Harris wrote a recent letter nounced the recent addition of Frank 0. to bring his record up to date. His office Shobe to the staff. is at 1117 South 20th St., in Birmingham, 1943 Ala., and his home is at 1348 44th Street Torrence A. Makley, Jr., is at the Eye West. Dr. Harris is married and has an Clinic of the University Hospital in Co- 11-year-old son, Edward Alun, Jr. The lumbus, Ohio. His home address is 915 following is a portion of his letter: "I E. 20th Ave. am practicing pediatrics and am a licen- Ernest T. Rouse announces the open- tiate of the American Board of Pediatrics, ing of his office at Suite 1011 in the Beau- a fellow of the American Academy of mont Medical Building in St. Louis with Pediatrics, assistant professor of pedi- practice limited to internal medicine. atrics at the Medical College of Alabama, former chief of pediatrics at Employees' 1944 Hospital in Fairfleld, Ala., immediate David S. Citron is with the U. S. Marine past president of the staff of Children's Hospital in Boston, Mass. Hospital in Birmingham, and hold active Bernard Bercu is at the McKinney Vet- membership on the staffs of Jefferson- erans Administration Hospital in Dallas, Hillman Hospital, Baptist Hospitals, and Texas. South Highland Infirmary. I am also a 1945 member of the courtesy staff at Carraway Samuel B. Guze is on the staff of the Methodist Hospital, Birmingham, and Veterans Administration Hospital in New- Employees' Hospital, Fairfield." ington, Conn. 1946 1938 William Stanbro is at George Washing- Frank Vellios is a first lietutenant in ton University Hospital in Washington, the Army Medical Corps, stationed at the 22nd General Hospital on Guam in the D. C. Mariana Islands. 1940 Joe S. Summers, Jr., recently moved 1947 from St. Paul, Minn., to Jefferson City, Robert Tanner recently moved from Mo., where he has offices in the Central St. Louis to 1922 North Circle Drive in Trust Building. Jefferson City, Mo. Kendall D. Gregory has moved from St. Louis to 426 Belleview, in Alton, 111. 1948 Henry T. Friedman has announced the John T. Gentry's present address is recent opening of his offices at 416 North 4509 Washington Ave., in St. Louis, but Bedford Drive in Beverly Hills, Calif., and after Sept. 30, he will be in the Office 144 WASHINGTON UNIVERSITY

of Professional Training of the New York to Santa Maria, Calif., where his address State Department of Health in Albany, is Route 1, Box 82-C. N. Y. Duane Taylor is in Cairo, 111., where Juro Sliintani has moved from St. Louis he can be reached at 418 Union Ave.

Jrt JHemnnam Deaths not reported previously in the ceived with appreciation a letter and con- Medical Alumni Quarterly: tribution from Mrs. McGinnis. 1886 1898 George H. Eversole of Caledonia, Mo., Hiram E. Silverstone of Kansas City, died October 4, 1948. Mo., died there on October 19, 1948. 1888 Ealph V. Smith died in Britain, Okla- John L. Higbie died November 12, 1948, homa, his home, on November 27, 1948. in Ohio. 1899 Nathan P. Thompson died in St. Louis Pinckney B. Carrigan of Hope, Ark., on October 31, 1948. died there on February 22, 1949. 1891 1900 Donnell M. Pearson of Louisiana, Mo., Richard Campbell died November 24, died there on October 12, 1948. 1948, in Illinois. 1903 1898 William J. Doyle, who had offices in the Joseph J. Meredith died June 27, 1949, Metropolitan Building in St. Louis, died in Cleveland, Ohio, where he had lived November 22, 1948. for the past three years. He was 84 years Charles Jf. Guhman of St. Louis died old and had practiced medicine in St. here June 5, 1949, aged 75. He was a Louis for 53 years before his retirement fellow in the A.M.A. and an honor mem- in 1946. He was honored by the St. Louis ber of the St. Louis Medical Society. Medical Society for 50 years of service in 1943. 1904 Minor W. Pitts of Lubing, Texas, died Chiles E. Keithly of Milo, Mo., died March 20, 1949. there November 12, 1948. 1895 1909 Robert J. Cnrdy of Kansas City, Mo., Frank H. Dillon died in Illinois on died December 15, 1948. November 6, 1948. 1896 1910 Charles Qnincy McGinnis died three Carl H. Wachenfeld of St. Louis died years ago on June 23, 1946, at White Me- on October 18, 1948. morial Hospital in Huntington Park, 1911 Calif., after a long illness due to a heart James Lewald of Laurel, Md., died Feb- ailment. The Alumni Office recently re- ruary 3, 1949. m H^H^^l^^^m^^'

WASHINGTON UNIVERSITY

Arthur H. Compton, Ph.D., Sc.D., LL.D.. Bridge Chancellor Charles Belknap, B.S., Vice Chancellor Edward K. Graham, Ph.D., Dean of Faculties Thomas Edward Blackwell, Ph.B., M.S., J.D., Director of Business Administration

The College of Liberal Arts Thomas S. Hall, Ph.D., Dean The School of Engineering Lawrence E. Stout, Ph.D., Ch.E., Dean The School of Architecture Joseph D. Murphy, Dean The School of Business and Public Administration Leslie J. Buchan, Ph.D., Dean The George Warren Brown School of Social Work Benjamin E. Youngdahl, A.M., Dean The Henry Shaw School of Botany Henry Nathaniel Andrews, Jr., Ph.D., Acting Dean The Graduate School of Arts and Sciences Carl Tolman, Ph.D., Dean The School of Law Wayne L. Townsend, A.B., LL.B., J.S.D., Dean The School of Medicine Robert A. Moore, M.D., Ph.D., Dean The School of Dentistry Otto W. Brandhorst, D.D.S., Dean The School of Nursing Louise Knapp, R.N., B.S., A.M., Director The School of Fine Arts Kenneth E. Hudson, B.F.A., Dean University College Willis H. Reals, Ph.D., Dean The Summer School Frank L. Wright, A.M., Ed.D., Director The Henry Edwin Sever Institute of Technology Lawrence E. Stout, Ph.D., Ch.E., Director