Syllabus Subject to Change with Notice!

MICR 434(G) IMMUNOLOGY

Wendell L. French, Ph.D. Spring 2012 Office: Rm 232 Phone 298-1294 Email: [email protected]

Office hours: Mon 11 a.m.-12 p.m., Tue 10 a.m.-12 p.m., Wed 11 a.m.-12 p.m. Lecture (Rm 202): Mon Wed 9:00-9:50 a.m. Lab (Rm 234): Thursday Sec. 41 10-11:50 a.m. Sec. 42 1-2:50 p.m.

SYLLABUS SUBJECT TO CHANGE WITH NOTICE!

Textbooks and other materials: Kuby IMMUNOLOGY. T. Kindt, R. Goldsby, and B. Osborne. 2007. 6th Edition. W.H. Freeman and Company, New York

Immunology Study Guide. 2005. K. C. Keudell

Web site: Immunology: www.whfreeman.com/immunology6e American Society for Microbiology: www.asmusa.org/ Center for Disease Control: www.cdc.gov/ WebCT: http://westernonline.wiu.edu = instructions will be given later

Course description: A study of antigens and antibodies, the immune response and immunity, immunologic testing, allergy and hypersensitivity, transplantation, autoimmune diseases, and cancer immunology. Laboratory includes selected immunologic techniques. Prerequisites: Bot 200, Micr 200, Zool 200, one year of chemistry. Exams and Grade Scale

Exam 1 50 pts. Exam 2 50 pts. Exam 3 50 pts. Final Exam 50 pts. Lab Exam 50 pts. Lab Attendance 28 pts. (2 pts. for each day present in lab) Assignments 40 pts. (10 pts. each) Quizzes 20 pts. Lab Exercises 80 pts. (10 pts. each) ______Total Points 418 pts.

UNDERGRAD GRADING SCALE

100-93% = A 92-90% = A- 89-87% = B+ 86-83% = B 82-80% = B- 79-77% = C+ 76-73% = C 72-70% = C- 69-67% = D+ 66-63% = D 62-60% = D- 59% and below = F

GRAD GRADING SCALE

A = 95-100% B = 85-94% C = 75-84% D = 65-74% F = below 65% Each exam may include short answer essay, fill-in-the-blanks, multiple choice, true false, or matching. Exam format will be discussed prior to each exam.

Lab exam: Information and format will be presented before the exam.

Assignments and unannounced/announced quizzes will be given throughout the semester.

Assignments: If you are not present in class the day the assignment is handed out, you will receive a zero. If you are excused for your absence the day the assignment is handed out, you will receive the assignment. Assignments are usually given a week before each lecture exam. All assignments must be submitted by the due date listed on the assignment instructions.

Unannounced/announced quizzes: If you are not present the day a quiz is given (unannounced or announced), you will receive a zero. If you are excused for your absence the day a quiz is given, you will have the opportunity to take the make-up quiz.

Make-up Exams: Make-up exams will only be given if you provide a valid excuse prior to the absence or valid documentation after-the-fact.

Late Work Policy: Assignments and written reports (lab exercises) will be docked 10% of their final grade per day that they are late.

Attendance: In order to get the most out of your education, you are expected to attend all lectures and labs and to be on time and stay for the entire class period. Attendance for a course such as this is critical to your understanding of the material. Attendance will be taken at the beginning of each class period in lecture as well as lab. Note that 2 unexcused laboratory absences will result in an automatic failure of the course. An excused absence requires proper documentation: if you are sick, provide me with a doctor’s note; if there is a family death, provide me with appropriate funeral documentation. Undocumented absences are considered unexcused by the University. Any combination of two incidences of coming to lab late and/or leaving lab early will be considered and treated as an unexcused absence.

Lecture exams will cover material presented in the text and in lecture. Notes for lectures will be available on WebCT Vista after the completion of each lecture unit. Access to WebCT Vista is available at: http://westernonline.wiu.edu/

CHEATING AND PLAGIARISM WILL NOT BE TOLERATED. Definition of Plagiarism The faculty of the Department of Biological Sciences ascribes to a definition of plagiarism as expressed by V. E. McMillan in Writing Papers in the Biological Sciences (Bedford/St.Martin’s Press, New York, pg 16)

“Plagiarism is the theft of someone else’s words, work, or ideas. It includes such acts as (1) turning in a friend’s paper and saying it is yours; (2) using another person’s data or ideas without acknowledgement; (3) copying an author’s exact words and putting them in your paper without quotation marks; and (4) using wording that is very similar to that of the original source but passing it off as entirely your own even while acknowledging the source.”

This includes information in textbooks or laboratory manuals, honors and masters theses, all writing assignments, and images. The faculty of the Department attempt to monitor student writing assignments (essay exams, papers, laboratory reports, and other writing assignments or exercises) for incidence of plagiarism. If plagiarism is found, the faculty will discuss the situation with the student and indicate to the student the penalty for this academic dishonesty. Potential penalties include those cited in the academic dishonesty section of the WIU web page.

Students with Disabilities: "In accordance with University policy and the Americans with Disabilities Act (ADA), academic accommodations may be made for any student who notifies the instructor of the need for an accommodation. For the instructor to provide the proper accommodation(s) you must obtain documentation of the need for an accommodation through Disability Resource Center (DRC) and provide it to the instructor. It is imperative that you take the initiative to bring such needs to the instructor's attention, as he/she is not legally permitted to inquire about such particular needs of students. Students who may require special assistance in emergency evacuations (i.e. fire, tornado, etc.) should contact the instructor as to the most appropriate procedures to follow in such an emergency. Contact Disability Resource Center at 298-2512 for additional services."

“Be Respectful” Policy: Be respectful in class. Please do not disturb other students by talking unnecessarily, reading the paper, passing notes, doing homework for another course, etc. during the class. PLEASE TURN OFF ALL CELL PHONES, BEEPERS, AND OTHER ELECTRONIC DEVICES DURING CLASS. If you repeatedly disturb the class with talking, your cell phone, etc., I will ask you to leave the class. Come to class on time and stay until the end. If you have a hard time hearing me, please don’t hesitate to ask me to talk louder, or move your seat as you need to be able to hear better. It is the student’s responsibility to be familiar with the information (including required forms, definitions, and time lines) contained in the following university web sites. Each student should access these web sites and carefully read the information they contain, your instructors will hold you responsible for knowing this information. If you have questions about any of the information contained in the web sites, ask your instructor:

Department of Biological Sciences Policies: http://www.wiu.edu/biology/about/policies.shtml

Student Rights and Responsibilities: http://www.wiu.edu/provost/student/

Final Exam Policy: http://www.wiu.edu/policies/finexam.php

Academic Integrity Policy: http://www.wiu.edu/policies/acintegrity.php

Grade Appeals Policy: http://www.wiu.edu/policies/gradeapp.php

STATE ACCREDITATION POLICY INFORMATION: “In accordance with Illinois State Board of Education certification rules, all candidates seeking teacher certification are required by Western Illinois University to obtain a grade of “C” or better in all directed general education course, all core courses, and all courses in the option. Note: A “C- ” is below a “C”.” Please note: any secondary science teacher certification student wanting to see how this course is aligned with the State and National Standards should see their advisor and/or examine the Secondary Science Teacher Certification WesternOnline Advising site.

SEE NEXT PAGE FOR CLASS SCHEDULE. MICR 434(G) IMMUNOLOGY CLASS SCHEDULE

Instructor: Wendell L. French, Ph.D. Spring 2012

Date Topic Unit; Chapter

1/18 Historical Aspects of Immunology Unit 1; 1 1/19 Lab: No Lab

1/23 Introduction to Immunology Unit 2; 1, 3 1/25 Introduction to Immunology Unit 2; 1, 3 1/26 Lab: Movie (The Fighting Edge)

1/30 Immunocytology Unit 3; 2 2/1 Immunocytology Unit 3; 2 2/2 Lab: Salmonella agglutination

2/6 Immunocytology Unit 3; 2 2/8 Immunocytology 2/9 Lab: Immunocytology (Blood Cells of the Immune System)

2/13 NO CLASSES LINCOLN’S BIRTHDAY 2/15 Antigens Unit 4; 4 2/16 Lab: Exam 1

2/20 Immunoglobulins and Antibody Diversity Unit 5; 4, 5 2/22 Immunological Techniques Unit 6; 6 2/23 Lab: Immunocytology (Lymphoid Tissue of the Immune System)

2/27 Immunological Techniques Unit 6; 6 2/29 Major Histocompatibility Complex and Unit 7; 8, 9 Antigen Processing and Presentation 3/1 Lab: Radial Immunodiffusion

3/5 Cytokines Unit 8; 12 3/7 Cell-Mediated Immune Response Unit 9; 10, 14 3/8 Lab: Results and Discussion on Radial Immunodiffusion; Detection of Epstein-Barr virus (EBV) using ELISA

3/12-3/16 SPRING BREAK

3/19 Cell-Mediated Immune Response Unit 9; 10, 14 3/21 B-Cells and the Immune Response Unit 10; 11 3/22 Lab: Exam 2; Results and Discussion for the Detection of EBV using ELISA 3/26 Complement System Unit 11; 7 3/28 Complement System Unit 11; 7 3/29 Lab: Simulated Detection of HIV-I using the Enzyme-linked immunosorbent assay (ELISA)

4/2 Inflammation Unit 12; 13 4/4 Hypersensitivity (Allergies) Unit 13; 15 4/5 Lab: Results and Discussion for Simulated Detection of HIV-1 by ELISA

4/9 Hypersensitivity (Allergies) Unit 13; 15 4/11 Immune Response to Infectious Diseases Unit 14; 18 4/12 Lab: Simulated Detection of HIV-1 by Western Blot (Agarose-based)

4/16 Immune Response to Infectious Diseases Unit 14; 18 4/18 Immunodeficiency Diseases Unit 15; 20 4/19 Lab: Exam 3, Results and Discussion for Simulated Detection of HIV-1 by Western Blot (Agarose-based)

4/23 Immunodeficiency Diseases Unit 15; 20 4/25 Autoimmunity Unit 16; 16 4/26 Lab: Lab Review

4/30 Transplantation Immunology Unit 17; 17 5/2 Cancer and the Immune Response Unit 18; 21 5/3 Lab: Laboratory exam

5/9 Final Exam Wednesday, 8-9:50 AM Rm. 202

SYLLABUS SCHEDULE SUBJECT TO CHANGE WITH NOTICE!