Curriculum Vitae s360

CURRICULUM VITAE

NAME: Eric Christopher Swindell

PRESENT TITLE: Assistant Professor of Pediatrics

ADDRESS: 5226 Yarwell Drive Houston, Texas 77096

CITIZENSHIP: U.S.A.

UNDERGRADUATE EDUCATION: 05/1992 B.S., Microbiology The University of Texas at Austin Austin, Texas

GRADUATE EDUCATION: 06/2001 Ph.D., Biochemistry/Developmental Biology Baylor College of Medicine Houston, Texas

POSTGRADUATE EDUCATION: 06/01- 07/03 Post-Doctoral Fellow Department of Biology/Center for Cancer Research Massachusetts Institute of Technology Cambridge, Massachusetts

08/03 - 07/08 Post-Doctoral Fellow Department of Genetics Baylor College of Medicine Houston, Texas

ACADEMIC APPOINTMENTS: 08/08 - pres. Assistant Professor of Pediatrics University of Texas Medical School at Houston Graduate School for Biomedical Sciences

PROFESSIONAL ORGANIZATIONS: The Society for Neuroscience (SfN) The International Society for Eye Research (ISER) The Association for Research in Vision and Ophthalmology (ARVO) Society for Developmental Biology American Association for the Advancement of Science

HONORS and AWARDS: First Place, Poster Competition, Graduate Student Symposium Baylor College of Medicine, Houston, TX, 1998 Meeting Award to attend Retinoids 99 Meeting, Strasbourg, France, 1999 National Science Foundation Award to attend the World Conference on Science, Budapest, Hungary, 1999 Page

NIH Training Grant Award, T32-GM07526, 2003-2004 NEI Training Grant Award, T32-EY07102, 2004-2006

NATIONAL GRANT REVIEW PANELS: National Science Foundation GRFP Panel 2012-present

SERVICE ON UNIVERSITY OF TEXAS MEDICAL SCHOOL AT HOUSTON: Member, Animal Welfare Committee 2011-present Member, Graduate Student Education Committee 2010-present

SERVICE ON GRADUATE SCHOOL COMMITTEES: Member, HMG Program Steering Committee 2012-present Member, HMG Program Admissions Committee 2012-present Member, GSBS Recruiting Council 2012-present

SPONSORSHIP OF CANDIDATES FOR POSTGRADUATE DEGREE: Specialized Masters Degree in Genetic Counseling Program Comm. Member Nevena Cvjetkovic 2011-2012

Masters Degree Committee Member Michael McCarthy 2011-2013

Ph.D. Degree GSBS Sponsor Samantha Berkey 2012-present

Ph.D. Degree GSBS Committee Member Yanran Wang 2010-present Jennifer Churchill 2012-present Jun Young Park 2012-present Ryan Singer 2012-present

Tutorial Supervised Yanran Wang 2010 Ryan Singer 2011 Samantha Berkey 2012

CURRENT TEACHING RESPONSIBILITIES: Lecturer, Developmental Biology Lecturer, Experimental Genetics Lecturer, Molecular & Cellular Approaches to Human Genetics Lecturer, Current Methods in Molecular Research I

CURRENT GRANT SUPPORT: NIH, R01DE11931, Hecht (PI), 09/01/12-08/31/17 Page

Mapping Nonsyndromic Cleft Lip and Palate Genetic Loci Role: Co-Investigator - 15% Effort

Departmental Grant, Department of Pediatrics, Swindell (PI), 09/01/08-present Research Start-Up Funds Role: PI

PREVIOUS GRANT SUPPORT: NIH, Post-Doctoral Training Grant Award, T32-GM07526, 2003-2004 NEI, Post-Doctoral Training Grant Award, T32-EY07102, 2004-2006

PUBLICATIONS: Refereed Original Articles in Journals: 1. Ghetie, V., Swindell, E., Uhr, J.W., and Vitetta, E.S. (1993) Purification and properties of immunotoxins containing one vs. two deglycosylated ricin A chains. J Immunol Methods 166:117-122. 2. Harper, J.W., Elledge, S.J., Keyomarsi, K., Dynlacht, B., Tsai, L.H., Zhang, P., Dobrowolski, S., Bai, C., Connell-Crowley, L., Swindell, E., Fox, M.P. and Wei, N. (1995) Inhibition of cyclin-dependent kinases by p21. Mol Biol Cell 6:387-400. 3. Dynlacht, B.D., Ngwu, C., Winston, J., Swindell, E.C., Elledge, S.J., Harlow, E., and Harper, J.W. (1997) Purification and analysis of CIP/KIP proteins. Methods Enzymol 283:230-244. 4. Swindell, E.C. and Eichele, G. (1999) Retinoid Metabolizing Enzymes in Development. BioFactors 10:85-90. 5. Swindell, E.C., Thaller, C., Sockanathan, S., Petkovich, M., Jessell, T.M., and Eichele, G. (1999) Complementary domains of retinoic acid production and degradation in the early chick embryo. Developmental Biology 216:282-296. 6. Lu, H.-C., Swindell, E.C., Sierralta, W.D., Eichele, G. and Thaller, C. (2001) Evidence for a role of protein kinase C in FGF signal transduction in the developing chick limb bud. Development 128: 2451- 2460. 7. Swindell, E.C., Moeller, C., Thaller, C and Eichele, G. (2001) Cloning and expression analysis of chicken Lix1, a founding member of a novel gene family. Mechanisms of Development 109: 405-408. 8. Moeller, C., Swindell, E.C., Kispert, A. and Eichele, G. (2003) Carboxypeptidase Z modulates Wnt signaling and regulates the development of skeletal elements. Development 130: 5103-5111. 9. Zilinski, C., Brownell, I., Hashimoto, R., Medina-Martinez, O., Swindell, E.C. and Jamrich, M. (2004). Expression of FoxE4 and Rx genes visualizes the timing and dynamics of critical processes taking place during initial stages of vertebrate eye development. Developmental Neuroscience 26 (5-6):294-307. 10. Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E.C., Farrington, S. and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. PNAS 101(35):12792-7. 11. Swindell, E.C., Bailey, T.J., Loosli, F., Liu, C., Wittbrodt, J. and Jamrich, M. (2006) Rx- Cre, a tool for inactivation of gene expression in the developing retina. Genesis 44 (8):361-3. Page

12. Swindell, E.C., Zilinski, C., Hashimoto, R., Shah, R., Lane, M.E.and Jamrich, M. (2008) Regulation and function of Foxe3 during early zebrafish development. Genesis 46 (3):177-183. 13. Swindell, E.C., Liu, C., Shah, R., Smith, A.N., Lang, R.A. and Jamrich, M. (2008) Eye formation in the absence of retina. Developmental Biology 322:56-64. 14. Liu, W., Lagutin, O., Swindell, E., Jamrich, M. and Oliver, G. (2010) Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate. J Clin Invest. 120(10):3568-77. 15. Park, B., Alves, C.H., Lundvig, D.M., Tanimoto, N., Beck, S.C., Huber, G., Richard, F., Klooster, J., Andlauer, T.F.M., Swindell, E.C., Jamrich, M., Le Bivic, A., Seeliger, M.W. and Wijnholds, J. (2011) PALS1 is essential for retinal pigment epithelium structure and neural retina stratification. J Neurosci. 31(47):17230-17241. 16. Dhande, O.S., Bhatt, S., Anishchenko, A., Elstrott, J., Iwasato, T., Swindell, E.C., Xu, H.-P., Jamrich, M., Itohara, S., Feller, M.B. and Crair, M.C. (2012) Role of Adenlyate Cyclase 1 in Retinofugal Map Development. J Comp Neurol. 520(7):1562-83. 17. Xu, X., Yi Shi, Y., Zhang, H.-M., Swindell, E.C., Marshall, A.G.,4, Guo, M., Kishi, S. and Yang, X.-L. (2012) Unique domain appended to vertebrate tRNA sythetase is essential for vascular development. Nat Commun. 3:681. 18. Cho, S.-H., Kim, J.Y., Simons, D.L., Song, J.Y., Le, J., Swindell, E.C., Jamrich, M., Wu, S.M. and Kim, S. (2012) Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber Congenital Amaurosis. Human Mol Genet. 21(12):2663- 76. 19. Yuan, Q., Chiquet, B.T., DeVault, L., Warman, M.L., Nakamura, Y., Swindell, E.C. and Hecht, J.T. (2012) Craniofacial abnormalities result from knock down of nonsyndromic clefting gene, crispld2, in zebrafish. Genesis 50(12):871-81. 20. Lu, F., Kar, D., Gruenig, N., Zhang, Z.W., Cousins, N., Rodgers, H.M., Swindell, E.C., Jamrich, M., Schuurmans, C., Mathers, P.H. and Kurrasch, D.M. (2013) Rax is a selector gene for hypothalamic feeding circuits. J Neurosci. 33(1):259-72. 21. Keeley PW, Luna G, Fariss RN, Skyles KA, Madsen NR, Raven MA, Poché RA, Swindell EC, Jamrich M, Oh EC, Swaroop A, Fisher SK, Reese BE. (2013) Development and plasticity of outer retinal circuitry following genetic removal of horizontal cells. J Neurosci. 33(45):17847-62.