Table 2: comprehensive complication index of transvaginal cholecystectomy grad ag CCI gra author year procedure N BMI range grade II grade IIIa e grade IVa p e de I mean IIIb DG Palanivel 2009 TVC 6 35 27 0 - 26 E/il biliary leak u9 6 eus intra oper ativ e colo wou n nd injur Salinas10 2009 TVC 12 46 0 - 34 infe 6 y, ctio bile n leak (re- lapa rosc opy) Linke11 2010 TVC 102 52 27 3 0 - 42 alle pleural gastric ulcer tran stroke rgic effusion, sum exa UTI bilic nth al em acc a, ess tran hern sien ia t par est hesi a, tran sien t urin ary rete ntio n, bac teri al vagi nosi s, vulv itis, deh isce nce of colp oto my clos ure vagi nal ble edi ng, um bilic al blee gra ding nul gall Federlein om intraoperative bladder 2010 TVC 115 52 28 0 - 34 UTI blad 12 1 a, laceration, biliary leak der intr foss aop a erat ive ser osal inju ry rect um Wood13 2013 TVC, TV 102 37 29 2 0 - 34 tran intraabdominal abscess ome VHR, sien ntal TVA t blee bra ding chia , l rect plex al us injur inju y ry, IUD disp lace me nt, urin ary rete ntio n, vagi nal gra nul atio n biliary pancreatitis, biliary Bulian14 2013 TVC 20 45 28 0 - 26 3 leak scenar 2014 lapa 4* 0 - 34 vagi roto io I nod my ynia for p < 0.000# , pelv UTI ic laparotomy , abs for clip lost alle ces TVC 41 54 29 from cystic rgic s scenar artery 7** 0 - 34 rea five stump io II ctio wee n to ks dre after ssin disc g harg e scenar CLC 51 54 30 vagi biliary stones intra 3* 0 - 28 nitis oper io I , ativ # scenar 8** 0 - 26 he e p < 0.000 io II mat sma om ll a, bow upp el er lace res ratio pira n, tory sym infe pto ctio mati n, c wou troc nd ar infe hern ctio ia n, after sut 12 ure mon gra th, nul dee om p a, wou alle nd Legend: year year of publication, procedure Palanivelu et al. and Salinas et al. used a flexible endoscope for transvaginal cholecystectomy (TVC), TV VHR transvaginal ventral hernia repair, TVA transvaginal appendectomy, CLC conventional three/four trocar cholecystectomy, N number of cases reported, BMI body mass index, CCI comprehensive complication index, SD standard deviation, DGE delayed gastric emptying, IUD intrauterine device, UTI urinary tract infection, grade I – IVa according to classification of surgical complications3, p level of significance Wilcoxon rank sum test, scenario I and II explained in text. *p < 0.90, **p < 0.46; #p scenario I vs. scenario II