26Th Meeting of European Intestinal Transport Group (EITG)

th 26 meeting of European Intestinal Transport Group (EITG)

Marstrand 2-5 October 2014

Thursday Oct 2nd

12:00: Lunch at Marstrand Havshotell

13:00: Welcome (H. Sjövall);

13:05-14:00: R.Naftalin (London, UK): Cultural history of intestinal transport – people, methods and roads ahead.

14:00-15:00: U.Seidler (Hannover, Germany): Intestinal chloride and bicarbonate transport – time to put the story together!

15:00-15:20: Aust, Kerner, Keysselt (Leipzig, Germany). CD97 regulates intestinal chloride transport.

15:20-15:40: Coffee break

15:40-16:40: J.Söderholm (Linköping, Sweden): Macromolecular transport in small and large intestine.

16:45-17:05: Falchuk, Amasheh and Markov (S:t Petersburg, Russia). Barrier characteristics of rat Peyer´s patches epithelium.

17:05-17:25: Prykhodko, Sureda, Zhou, Chopek, Fedkiv, Pierzynowski, Weström (Lund, Sweden). In vivo macromolecule absorption in wild-type and immunodeficient athymic neonatal rats during lectin-induced maturation.

17:30-18:30: M. Jodal. Ove Lundgren memorial lecture: Ove Lundgren and the integrative physiology of intestinal transport.

19:00: Dinner at Marstrand Havshotell – traditional Swedish crayfish party. Friday Oct 3rd

08:00-08:20: Fromm, Rosenthal, Günzel, Schulzke, Yu (Berlin, Germany). Claudin-2: Water and sodium pass through a common pore.

08:20-08:40: Sommansson, Wan Saudi, Nylander, Sjöblom (Uppsala, Sweden). Effects of melatonin in ethanol- induced increases in duodenal mucosal permeability, motility and bicarbonate secretion in rats.

08:40-09:00: Bader and Diener (Giessen, Germany). Novel aspects of cholinergic regulation of intestinal ion secretion.

09:00-09:20: Sedin, Sjöblom, Nylander (Uppsala, Sweden). Clonidine abolishes the hypotonicity-induced increase in duodenal mucosal permeability in an á2- adrenoceptor-mediated mechanism in rats.

09:20-09:40: Bell, Althaus, Diener (Giessen, Germany). Communication between mast cells and rat submucosal neurons.

09:40-10:00: Zakrzewski, Fromm, Schulzke, Günzel (Berlin, Germany). Zinc strengthens the jejunal barrier by affecting the paracellular route.

10:00-10:30: Coffe break

10:30-11:30: K.Sundell (Göteborg, Sweden): Developmental changes of the intestinal epithelium in salmon.

11:30-11:50: Cavin, Ducroc, Arapis, Coulevard, Bado, Gall (Paris, France). Reprogramming of intestinal sugar transporters after bariatric surgery.

11:50-12:10: Dengler, Rackwitz, Gäbel (Leipzig, Germany). In vitro-simulation of ischemia in equine jejunum epithelium – effects on functional and molecular level.

12:10-13:00: Lunch

13:00-14:00: F. Bäckhed (Göteborg, Sweden). Microbiota, barrier function and the link to metabolism.

14:00-14:20: Layunta, Latorre, Grasa, Castro, Plaza, Pardo, Santiago, Sanchez de Medina, Matrinez-Augustin, Ocon, Aranda, Mesonero, Alcalde (Zaragoza, Spain). Expression of microbiota recognition receptors and intestinal serotoninergic system in two mouse models of colitis.

14:20-14:40: Zietek, Rath, Röder, Haller, Daniel (Freising, Germany). Intestinal sugar transporters as sensors for incretin secretion: studies in mice and murine gut organoids.

14:40-15:00: Coffee

15:00-15:30: “Please come to see my poster”-session (each poster summarized in 2-3 minutes)

15:30-18:00: Poster session, with drinks.

 Damm, Jensen, Mahmood, Bindslev, Berner Hansen. Acetylcholine and colonic epithelial transport in patients with colorectal neoplasia

 Elfers K, Wilkens MR, Breves G, Muscher-Banse AS. Modulation of intestinal calcium and phosphate transport in young goats by changes in dietary nitrogen and/or calcium intake.

 Nati Hernando, Kumar Myakala, Fabia Simona, Heini Murer, Carsten A Wagner and Jürg Biber. Characterization of intestinal-specific NaPi-IIb/Slc34a2 deficient mice  Höfer, Dahlke, Schlupp, Schmidts, Runkel. Porcine small intestine to study drug transport.

 Gil-Iturbe, Pujol-Giménez, Castilla-Madrigal, Lostao. Expression of the glucose transporter GLUT12 in small intestine.

 Mahmood, Damm, Jensen, Bindslev, Berner-Hansen. Effects of phosphodiesterase inhibitors on colonic epithelial transport in patients with colorectal neoplasia  Sureda, Prykhodko, Pierzynowsk, Weström. Role and expression of neonatal-fc-receptor in the small intestine during normal and precociously induced maturation in the neonatal rat.

 Bennet, Sapnara, Sjovall, Gustafsson, Eutamene, Le Neve, Törnblom, Öhman, Simrén. Electrophysiological properties of colon biopsies from patients with irritable bowel syndrome are altered by exposure to E.coli.

 Zeyi, Dejiang, Yuqiong, Zhi. Absorption Mechanism of theGreenTea Catechins by the Human Intestinal Cell Line Caco-2

20:00: Dinner at Marstrand Havshotell, theme Swedish Summer. Entertainment by Axel Falk, singer and songwriter.

Saturday Oct 4th

08:00-09:00: G.Hansson (Göteborg, Sweden): Regulation and function of the intestinal mucin system.

09:00-09.20: Vörös, Staib, Ocvork, Fuchs, Haller, Daniel, Spanier (Freising, Germany). Interplay of the dual oxidase duox2 with the sodium-proton exchanger NHE3 in intestinal pathogen defence.

09:20-09:40: Wising, Almqvist, Eklund, Törnblom, Simren, Johansson, Hansson, Sjövall (Göteborg, Sweden). Normal sigmoid penetrability to fluorescence beads the size of bacteria in patients with irritable bowel syndrome.

09:40-10:00: Stormvind, refreshing activity with qigong.

10:00-11:00: J.Schulzke: Effects of inflammation on the colonic epithelium.

11:00-11:20: Latorre, Layunta, Gimeno, Grasa, Castro, Garcia, Gros, Arruebo, Alcade, Mesonero (Zaragoza, Spain). Oxidative stress balance between pro- and anti-inflammatory factors in human intestinal epithelial cells.

11:20-11:40: Priyamvada, Anbazhagan, Kumar, Gujral, Borthakur, Saksena, Gill, Alrefai, Dudeja (Chicago, US). All-trans-retinoic acid (ATRA): A novel potential therapeutic agent for inflammatory diarrhea.

12:00-13:00: Lunch at Marstrands Havshotell

3 13:00-13:20: Layunta , Latorre, Gimeno, Grasa, Castro, Plaza, Pardo, Gomollón F , Alcalde, Mesonero (Zaragoza, Spain). Toll-like Receptor 9 activation affects intestinal serotonin transporter activity and expression in Caco-2 cells 13:20-13:40: Jensen, Mahmood, Damm, Bindslev, Berner Hansen (Copenhagen, Denmark). Effect of cyclooxygenase inhibitors on colonic epithelial transport in patients with colorectal neoplasia

13:40-14.00: H.Sjovall. Meeting sumup.

14.00: General discussion, including format and location of future meetings.

17.00: Meet at the lobby, joint departure for dinner at the fortress. 17.30: Guided tour of fortress, pickup at harbour.

19:00: Dinner at Carlsten Fortress, four course Viking Dinner. Theme: Swedish history.

Sunday Oct 5th

Breakfast and departure, checkout time 10.00

On demand: Joint departure with bus from Marstrands Havshotell. First stop Göteborg City Airport, second stop Central Station in Göteborg for change to Airport Bus.