Naoyuki Taniguchi MD

Naoyuki Taniguchi MD. PhD. Program Director, Systems Glycobiology Research Group Chemical Biology Department, Advanced Science Institute, RIKEN Endowed Professor of Disease Glycomics (Seikagaku Corporation) Research Institute for Microbial Diseases, Osaka University Educational Training MD 1967 Hokkaido University Medical School PhD. 1972 Hokkaido University [email protected] POSITIONS AND HONORS 10/76-9/77 Visiting Associate Professor, Department of Biochemistry, Cornell University Medical School, NY, USA 5/79-3/86 Associate Professor, Biochemistry Laboratory, Cancer Institute, Hokkaido University School of Medicine, Sapporo Japan 4/86-3/06 Professor and Chair, Department of Biochemistry, Osaka University Graduate School of Medicine, Osaka, Japan 10/05 – present Member of Science Council of Japan 4/06 -present Endowed Chair Professor, Department of Disease Glycomics, Research Institute for Microbial Diseases, Osaka University, 10/08 Program Director of Systems Glycobiology Research Group and team leader of Disease Glycomics, Advanced Science Institute, RIKEN Award 2002 Japan Medical Association Prize, Takeda Foundation Prize, International Glycoconjugate Organization (IGO) Award, 2005 Medal with Purple Ribbon from Emperor, Japan ,2008 IUBMB medal and lecture Selected publications 1)Taniguchi N. Nature Chem Biology 3:307-309,2007 2) Taniguchi N, Miyoshi E, Gu J, Honke K and Matsumoto A. Decoding sugar functions by identifying target glycoproteins. Curr. Opin. Struct. Biol., 16, 561-566, 2006. 3) Wang X, Inoue S, Gu J, Miyoshi E, Noda K, Li W, Mizuno-Horikawa Y, Nakano M, Asahi M, Takahashi M, Uozumi N, Ihara S, Lee S H, Ikeda Y, Yamaguchi Y, Aze Y, Tomiyama Y, Fujii J, Suzuki K, Kondo A, Shapiro S D, Lopez-Otin C, Kuwaki T, Okabe M, Honke K and Taniguchi N. From The Cover: Dysregulation of TGF-{beta}1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice. Proc. Natl. Acad. Sci. U.S.A., 102, 15791-15796, 2005. 4)Yoshimura M, Ihara Y, Matsuzawa Y and Taniguchi N. Aberrant glycosylation of E-cadherinen hances cell-cell binding to suppress metastasis. J. Biol. Chem., 271, 13811- 13815, 1996. 5) Uozumi N, Yanagidani S, Miyoshi E, Ihara Y, Sakuma T, Gao C X, Teshima T, Fujii S, Shiba T and Taniguchi N. Purification and cDNA cloning of porcine brain GDP-L-fuc: N- acetyl- -D-glucosaminide: alfa1-6fucosyltransferase. J. Biol. Chem., 271, 27810-27817, 1996. 6) Nishikawa A, Ihara Y, Hatakeyama M, Kangawa K and Taniguchi N. Purification, cDNA cloning, and expression of UDP-N-acetylglucosamine alfa-D-mannoside beta1-4N- acetylglucosaminyltransferase III from rat kidney. J. Biol. Chem., 267, 18199-18204, 1992.