RSO Review Notes of Human Subjects Research Involving the Use of Radiation

Estimated Effective Doses from Various Medical Imaging Procedures

Reference Radiology HPS Info uthscsa UTxSW Effective Dose (mrem) Single radiographs Abdomen (AP)1 70 120 Abdomen6 53 Abdomen-KUB 120 140 Angiogram - Coronary 460 - 1,580 3000 Angiography - Abdominal 1044 Angiography - Cerebral 689 Angiography - digital carotid 400 Angiography - digital femoral 400 Angiography - digital hepatic 2200 Angiography - digital renal 1400 Barium enema (10 images, 137 sec 700 410 fluoroscopy)1 710 Barium follow-up (4 images, 78 sec 300 fluoroscopy)1 Barium meal (11 images, 121 sec 300 fluoroscopy)1 Barium swallow (24 images, 106 sec 150 fluoroscopy)1 330 Biliary 189 Bitewing dental film6 0.4 Cervical spine series6 27 20 20 Chest (lateral)1 4 Chest (PA and lateral)5 6 4 5 Chest (PA)1 2 10 3 Cholecystography 100 Cine Fluoro (per minute) 120/min CT (head or chest)5 1,110 CT abdomen1 1,000 1,000 1147 m 860 CT abdomen 1311 f CT Body 1,000 CT Cardiac for Calcium Scoring 200 CT chest1 800 800 880 m 740 CT chest1 1059 f CT Coloography 500 CT head1 200 200 200 200 CT lumbar spine 730 CT pelvis1 1,000 987 CT pelvis1 1,479 CT Sinuses 60 CT Spine 1,000 Dental intra-oral 0.4 Dental Panoramic 1 DEXA- men 1 6 DEXA-Forearm 10 DEXA-Hip 10 DEXA-Lateral spine 35 DEXA-Lumbar spine 10 Estimated Effective Doses from Various Medical Imaging Procedures

Reference Radiology HPS Info uthscsa UTxSW Effective Dose (mrem) DEXA-Whole Body 1.5 DEXA-women 1 Diagnostic Cardiac 3000 Intravenous Pyelogram (kidneys, 6 films)1 250 160 250 Limbs and joints6 6 1 1 Lower GI 400 Lumbar L5-S1 50 Lumbar spine (AP)1 70 90 Lumbar spine (lateral)1 30 43 53 Lumbar spine series6 180 230 Mammogram6 13 70 200 per view 35 Myelography 400 Pelvis (AP)1 70 70 150 Pelvis or hips6 83 83 83 PTCA (heart study)6 750 - 5,700 Skeletal Survey 350 Skull (lateral)1 1 3 Skull (PA or AP)1 3 2 6 Skull Series 15 Thoracic spine (AP)1 40 48 Thoracic spine (lateral)1 30 29 Thoracic spine series6 140 100 90 Upper GI 200 150

Effective, whole-body doses for routine nuclear medicine studies at KU Hospital Nuclear Medical Activity Effective Dose Scan (mCi) Radiopharmaceutical (mrem) Brain2 30 99m+Tc ECD 975 Brain4 30 99mTc HMPAO 1035 Thyroid scan 10 99mTc pertechnetate Thyroid scan-cancer 4 131I NaI Thyroid - 0.015 131I NaI Hyperthyroidism Hepatobiliary2 5 99mTc Mebrofenin 370 Bone2 20 99mTc MDP 440 Lung 5 & 10-30 99mTc MAA & 133Xe 150-450 Perfusion/Ventilation2 Kidney3 20 99mTc MAG3 520 Tumor2 3 67Ga 1,220 Heart3 30 99mTc sestimibi 890 Heart3 MUGA 30 99mTc pertechnetate 1,440 Heart4 2 201Tl chloride 1,700 Heart4 30 99mTc tetrofosmin 845 Prostate Cancer 5 111In Prostacint Gastric Emptying7 1 99mTc Sulfur Colloid 93 Various3 15 18F FDG 1050 References:

Health Risks from Exposure to Low Levels of Ionizing Radiation: “Biological Effects of Ionizing Radiation (BEIR) VII, Phase 2. National Academy of Sciences, 2006.

Health Physics Society.

“Radiation Aspects Of Informed Consent Statements For Clinical Research Projects In Which Radiation Exposure Is For Research Purpose And Not For The Medical Benefit Of The Subject (Patients And Normals)”, University of Maryland, http://www.ehs.umaryland.edu/rad/pdf/Required%20Consent%20Form.pdf, Accessed 3/3/2008

Guidelines for Radiation Statements, Johns Hopkins Medicine,

RSF-035 Human Use of Radiation Guidance, University of Texas Southwestern: http://www.utsouthwestern.edu/vgn/images/portal/cit_56417/0/11/332383RSF-035__pdf.pdf, Accessed 3/3/2008

IRB Information about the Use of Radiation in Human Research Studies, http://www.uthscsa.edu/irb/appendix19.doc Accessed 3/3/2008