Lawrence Israel Schwartz, M.D

CURRICULUM VITAE Lawrence Israel Schwartz, M.D.

Date: July 9, 2011

Personal Information Date of Birth: November 24, 1969 Place of Birth: Pittsburgh, Pennsylvania Spouse: Evelyn Becker Children: Caleb Becker-Schwartz Adina Becker-Schwartz

Address and Telephone Numbers Home: 2592 Bexley Park Road Bexley, OH 43209

Telephone: (614) 312-1363 cell (614) 235-4794 home

Office: Nationwide Children’s Hospital Department of Anesthesiology 700 Children’s Drive Columbus, OH 43205 Telephone: (614) 722-4200 Email: [email protected]

Current Position Clinical Assistant Professor of Pediatric Anesthesiology and Critical Care Medicine Director of Education, Department of Anesthesiology Nationwide Children’s Hospital and Ohio State University, Sept 2010 - present

Previous Positions Clinical Assistant Professor of Pediatric Anesthesiology and Critical Care Medicine Department of Anesthesiology Director, Cardiothoracic Intensive Care Unit The Heart Center at Nationwide Children’s Hospital Nationwide Children’s Hospital and Ohio State University, March 2006 – August 2010

Assistant Professor of Pediatric Anesthesiology and Critical Care Medicine Medical Director, PICU Transport Program Division of Pediatric Anesthesiology and Critical Care Medicine Department of Anesthesiology and Critical Care Medicine Johns Hopkins University School of Medicine, July 2004 – March 2006 2

Curriculum Vitae – Lawrence Israel Schwartz, MD

Clinical Fellow of Pediatric Anesthesiology Division of Pediatric Anesthesiology and Critical Care Medicine Department of Anesthesiology and Critical Care Medicine Johns Hopkins University School of Medicine, July 2002 – June 2004

Clinical Fellow of Pediatric Critical Care Medicine Division of Pediatric Anesthesiology and Critical Care Medicine Department of Anesthesiology and Critical Care Medicine Johns Hopkins University School of Medicine, July 2002 – June 2004

Attending Physician Division of Pediatric Emergency Medicine Department of Emergency Medicine Sinai Hospital of Baltimore, Maryland, May 2000 – June 2004

Education Undergraduate: 1987.1990 B.A. History, honors. Washington University. St. Louis, Missouri

Graduate: 1991.1995 M.D. University of Pittsburgh. Pittsburgh, Pennsylvania

Postgraduate: 1996-1999 Intern/Resident in Pediatrics. Sinai Hospital of Baltimore. Baltimore, Maryland 1999-2002 Resident in Anesthesiology. Johns Hopkins Hospital, Johns Hopkins University. Baltimore, Maryland 2002- 2004 Pediatric Anesthesiology Fellow. Johns Hopkins Hospital, Johns Hopkins University. Baltimore, Maryland 2002- 2004 Pediatric Critical Care Fellow. Johns Hopkins Hospital, Johns Hopkins University. Baltimore, Maryland

Medical Licensure and Board Certification Licensure: Ohio Maryland

Board Certification: 1996 Diplomate, National Board of Medical Examiners 1999 Diplomate, American Board of Pediatrics, recertified 2006 2003 Diplomate, American Board of Anesthesiologists 2004 Diplomate, American Board of Pediatrics, Subboard of Pediatric Critical Care Medicine 3

Honors and Awards 1987-1990 Dean’s List 7 of 7 Semesters. Washington University, St. Louis, Missouri 1991 Phi Beta Kappa 1995 C.F. Reynolds History of Medicine Society. Best Paper for “World War Two and its Effect on the Production and Development of Penicillin”

Professional Societies and Organizations American Society of Anesthesiologists Society for Critical Care Medicine Society for Pediatric Anesthesia Pediatric Cardiac Intensive Care Society Congenital Cardiac Anesthesia Society Society of Cardiovascular Anesthesia International Anesthesia Research Society

Hospital Committees Served Nationwide Children's Hospital, The Heart Center Research Resource Committee Nationwide Children's Hospital, Department of Anesthesiology, Academic Committee Nationwide Children's Hospital, CTICU Design Committee for Replacement Hospital Nationwide Children’s Hospital, Critical Care Quality Review Committee Nationwide Children's Hospital, Zero Hero Training Team. Hospital Safety Initiative. Nationwide Children's Hospital, Department of Anesthesiology, Leadership Transition

Lectures and Presentations Pediatric Rapid Sequence Induction. Sinai Hospital of Baltimore, Emergency Department. August, 2001

Pediatric Shock. Johns Hopkins Hospital, Pediatric Resident Lecture Series. November, 2002

Single Ventricle Physiology. Johns Hopkins Hospital, Anesthesiology Resident Lecture Series. February, 2002

Pediatric Rapid Sequence Induction. Sinai Hospital of Baltimore, Pediatric Resident Lecture Series. April, 2002

Characterization of Syndecan in Human Pulmonary Artery Endothelial Cells: Inflammatory Stress Response. Johns Hopkins Hospital, Department of Anesthesiology and Critical Care Medicine Scientific Poster Day. October, 2002

Monitoring and Vigilance. Seminar: Pediatric Sedation for Non-Anesthesia Personnel. Johns Hopkins Hospital. November, 2002 4

CPR/Airway Workshop. Seminar: Pediatric Sedation for Non-Anesthesia Personnel. Johns Hopkins Hospital. November, 2002

ECMO Pathophysiology. Seminar: ECMO for Respiratory Therapists / Perfusionists. Johns Hopkins Hospital. September, 2003

Seminar: Pediatric Sedation for Non-Anesthesia Personnel. Johns Hopkins Hospital. January, 2004

The Pediatric Airway. PICU Fellow Orientation. Johns Hopkins Hospital. July, 2004

Malignant Hypertension. PICU Fellow Orientation. Johns Hopkins Hospital. July, 2004

Introduction to Pediatric Anesthesia. Medical Student Lecture Series. Johns Hopkins Hospital. August, 2004

The Pediatric Airway. Pediatric Resident Lecture Series. Johns Hopkins Hospital. September, 2004

Congenital Heart Disease. Anesthesia Resident Lecture Series. Johns Hopkins Hospital. October, 2004

Pediatric Cardiopulmonary Bypass. Pediatric Anesthesia Fellow Lecture Series. Johns Hopkins Hospital. March, 2005

Cardiomyopathy. Pediatric Anesthesia Fellow Lecture Series. Johns Hopkins Hospital. January, 2006

Pediatric Perioperative CPR. Pediatric Anesthesiology Lecture Series. Columbus Children’s Hospital. 2006 – present

Anesthesia and the Pediatrician. 2007 Pediatric Pearls Conference. Columbus Childrens Hospital. February, 2007

Surgical and Anesthetic Management of Patients with Congenital Heart Disease. Guest Speaker. American Society of Dentist Anesthesiologists. Annual Meeting, Orlando, FL. March, 2007

Anesthesia for the Pediatric Cardiologist. Cardiology Lecture Series. Columbus Children’s Hospital. June 2007.

Anesthesia for Congenital Heart Patients having Non-cardiac Surgery. Cardiology Lecture Series. Nationwide Children's Hospital, Columbus, OH. May 2008. 5

Pediatric Airway. PCCM Fellow Lecture Series. Nationwide Children's Hospital, Columbus, OH. July 2008.

The Pathophysiology of Bypass, Pediatric Residency Lecture Series. Nationwide Children's Hospital, Columbus, OH. July 2009.

Anesthesia for the Pediatric Cardiologist. Cardiology Lecture Series. Nationwide Children's Hospital. January 2010.

Delayed Emergence and Prolonged Relaxation. Department of Anesthesiology, Grand Rounds. Nationwide Children's Hospital. November 2010.

Introduction to Pediatric Anesthesiology. Guest Speaker. Department of Anesthesiology, Ohio State University. December 2010.

Perioperative Respiratory Complications in Pediatric Patients. Department of Anesthesiology, Grand Rounds, Nationwide Children's Hospital. April 2011.

Inflation of cuffed endotracheal tubes in children results in excessive cuff pressures. Accepted for Poster Discussion Presentation. Annual Meeting of the American Society of Anesthesiologists. October 2011.

Research / Academic Projects 1991 The development of animal models to study fatal arrhythmias and sudden death, with Steve Pogwizd, M.D. Washington University, St. Louis, Missouri

1999 Retrospective study on the effect of CPAP on oxygenation of children in status asthmaticus, with Aaron Zuckerberg, M.D. Sinai Hospital of Baltimore

2001- 2003 Investigation of syndecan and the glycocalyx role in lung vasculature permeability, with Randal Dull, M.D., Ph.D. Johns Hopkins Hospital, Baltimore, Maryland

2002 Introduction to teaching and learning in medicine: Principles, practices, and issues. Johns Hopkins University, Baltimore, Maryland

2004 Development of a formal curriculum for pediatric residents’ four week rotation in the Pediatric Intensive Care Unit, with Leah Harris, MD. Johns Hopkins Hospital, Baltimore, Maryland

2004 Johns Hopkins Faculty Development in Teaching Skills. Johns Hopkins University, Baltimore, Maryland 6

2007 Development of curriculum for pediatric residents’ four week rotation in the Pediatric Cardiothoracic Intensive Care Unit. Columbus Children’s Hospital, Columbus, Ohio

2009 Post-operative ECG ST and T wave chages in Pediatric Congenital Heart Disease Undergoing Patent Ductus Arteriosus Stenting and Bilateral Pulmonary Banding. Nationwide Children's Hospital, Columbus, Ohio.

2009 Comparison of Anesthetic Techniques for Cardiac Surgical Stress Response Reduction. Nationwide Children's Hospital, Columbus, Ohio.

2009 Anesthetic Management of the Hybrid Procedure for HLHS

2010-11 Development of Educational Curriculum and Programming for Department of Anesthesiology, including: Resident Lecture Series, Resident Curriculum, and Grand Rounds series. Nationwide Children's Hospital, Columbus, Ohio

Clinical Title and Responsibilities Clinical Assistant Professor of Pediatric Anesthesiology Nationwide Children’s Hospital, Columbus Ohio Responsibilities include formation and implementation of anesthetic plan for children undergoing procedures in the operating room and remote locations. Practice includes cardiothoracic, transplant, neurosurgical, trauma and neonatal patients.

Teaching Title and Responsibilities Director of Education, Clinical Assistant Professor of Pediatric Anesthesiology Nationwide Children’s Hospital, Columbus Ohio Responsibilities include development and implementation of resident and student didactic and clinical curriculum, as well as staff continuing medical education programs. Responsibilities also include teaching and supervising medical students, nurse anesthetists, anesthesiology residents, and pediatric anesthesiology fellows in the operating room.

Publications Randal O. Dull, Ramani Dinavahi, Lawrence I. Schwartz, Donald Humphries, Joe G. N. Garcia. Lung Endothelial Heparan Sulfates Mediate Cationic Peptide-Induced Barrier Dysfunction: A New Role for the Glycocalyx. American Journal of Physiology – Lung, Cellular, and Molecular Physiology. 285: L986-L995. 2003

Randal O. Dull, Bracken J. Dewitt, Ramani Dinavahi, Lawrence I. Schwartz, Nathan Pace, Clara Fronticelli. Hemoglobins Directly Induce Endothelial Barrier Dysfunction: 7

Quantitative Assessment of Macromolecular Permeability. Journal of Applied Physiology. 97: 1930-1937. 2004

Aymen N Naguib, Peter Winch, Lawrence Schwartz, Janet Isaacs, Roberta Rodeman, John P Cheatham, Mark Galantowicz. Anesthetic Management of the Hybrid Stage 1 Procedure for Hypoplastic Left Heart Syndrome. Pediatric Anesthesia. 20:38-46. 2010

Tyler Burnett, Lawrence Schwartz, Joseph D. Tobias. Anesthesia with dexmedetomidine and remifentanil in a child with mitochondrial myopathy. South African Journal of Anaesthesia and Analgesia. 17(3): 262-264. 2011

Joseph D Tobias, Lawrence Schwartz, Julie Rice, Kris Jatana, Richard Kang. Cuffed endotracheal tubes in infants and childrens: Should we routinely measure cuff pressure? Manuscript in preparation.

Abstracts T.L Astor, F.R. Long, P. Baker, L. Schwartz, M. Galantowicz, A. Phillips, R. Castile. Concurrent Use of Controlled Ventilation Computed Tomography, Pulmonary Function Testing, and Bronchoscopy Biopsy for Allograft Rejection/Infection Surveillance in Infant Lung Transplant Recipients. The International Conference of the American Thoracic Society. San Francisco, May 2007.

Fischer A, Schwartz L, Galantowicz M, Chan D. Post-Operative Electrocardiogram ST and T Wave Changes in Pediatric Congenital Heart Disease Undergoing Patent Ductus Arteriosus Stenting and Bilateral Pulmonary Artery Banding. CHOP Cardiology Conference. Orlando, Feb 2010.

Alistair Phillips, Melissa Cannon, Keyana Milton, Larry Schwartz, Aymen Naguib, Vince Olshove, Mark Galantowicz. Decreased Significant Events with Dedicated Cardiothoracic Surgery Intensive Care Unit. Society of Thoracic Surgery. 2010.

Schwartz L, Rice J, Jatana K, Kang R, Tobias T. Inflation of cuffed endotracheal tubes in children results in excessive cuff pressures. Accepted for Poster Discussion Presentation. Annual Meeting of the American Society of Anesthesiologists. October 2011.