L. Painful Procedures

L. PAINFUL PROCEDURES

1. Will your study be concerned with the effects of TRAUMA? Yes ☐ No ☐

2. Will your study be concerned with the effects of BURNS? Yes ☐ No ☐

3. Will you be studying PAIN? Yes ☐ No ☐

4. Will you be using ELECTRIC SHOCK? Yes ☐ No ☐

If “YES” to any of the above, complete the following:

a. Describe the procedure in detail:

b. i. State your proposed procedures to avoid or alleviate the pain:

ii. State the anesthetic or analgesic agents, dosages, route and intervals between doses to be used for each species:

iii. Provide justification if you do not intend to use anesthetic or analgesic:

c. Describe the monitoring schedule:

d. State the impairment that can be expected from the procedure:

e. State the duration of survival after the procedure:

5. Will you be using paralytic agents* or performing paralytic procedures? Yes ☐ No ☐

(*Examples include, but are not limited to: Succinylcholine chloride, Decamethonium bromide, D-Tubocurarine chloride, Gallamine triethiodide, Pancuronium bromide, Vecuronium bromide, Atracurium besylate, Mivacurium, Doxacurium, and Pipecuronium.)

If "YES", complete the following: a. Describe the procedure/use of agent in detail: b. Provide scientific justification for the use of paralytic agent/procedure(s): c. Describe the impairment expected from the procedure: d. i. Describe your proposed procedures to avoid or alleviate pain:

ii. State the criteria to evaluate pain (inability to reach food and water, etc) and what will be done to alleviate pain:

iii. State the anesthetic or analgesic agents and dosages to be used for each species: e. State whether the animals will be able to urinate/defecate properly, and if not, what will be done to assist the animal: f. Describe your monitoring plan. g. State the duration of survival after the procedure: