Weighing and Diluting of Salts Into Water

Cadmium chloride, hydrated Cupric sulphate pentahydrate Lead (II) nitrate

Manganese sulphate monohydrateHazardous Substances Policy - Assessment CHEMICAL HAZARD AND RISK ASSESSMENT School of Biosciences

Name of Professor Ted Taylor Assessment Number* 2008 supervisor Signature Assessor Ruth Hayes Date of Assessment 22/3/02 Signature

Notes A School COSHH form in Word is available on the School Server. Available from the Health and Safety Unit. Guidance on making an assessment is given in Making a Chemical Hazard and Risk Assessment. Guidance is also available from Guidance on Completing the Chemical Hazard and Risk Assessment Form. Use a continuation sheet to expand any section of this form in hard copy version.

1 LOCATION OF THE WORK ACTIVITY W119, NB1, NB1A

2 PERSONS WHO MAY BE AT RISK List names where possible Ruth Hayes, and / or any others working in BMSU

3 ACTIVITY ASSESSED Weighing and diluting of salts into water

4 MATERIALS INVOLVED Attach copies of data sheet(s) NAME AMOUNT HAZARD RISK PHRASES HAZDAT NO*** BIOSCIENCESNO*** max/stored Cadmium chloride, 100 g Irritant. R36/37/38: Irritating to hydrated Harmful. eyes, respiratory tract and Toxic. skin. Cancer R22: Harmful if swallowed. hazard. R23: Toxic by inhalation. R45: May cause cancer. R46: May cause heritable gene damage.

Cupric sulphate 250 g Toxic. R25: Toxic if swallowed.. pentahydrate Harmful. R22: Harmful if swallowed. Irritant. R36/38: Irritating to eyes and skin.

Lead (II) nitrate 500 g Oxidizing. Strong oxidiser. Flammable. R8: certain incompatible Irritant. materials cause Cancer combustion. hazard. R36/38: Irritating to eyes and skin. R45: May cause cancer. R46: May cause heritable gene damage.

Manganese sulphate 100 g Harmful. R20/21/22: Harmful by monohydrate Irritant. inhalation, in contact with skin and if swallowed. R36/37/38: Irritating to eyes, respiratory tract and skin.

Nickel chloride 100 g Toxic. R25: Toxic if swallowed. hexahydrate Zinc sulphate 500 g Irritant. R36/37/38: Irritating to heptahydrate eyes, respiratory tract and skin.

5 INTENDED USE** Give brief details and attach protocol/instructions Weighed amounts of the salts will be diluted into 220 litres dechlorinated tap water in a labelled barrel. This will then be pumped into an aquarium at a 1 in 100 dilution to give final concentrations of zinc at 27.8 g/L; manganese at 23.0 g/L; nickel at 19.6 g/L; copper at 1.3 g/L, lead at 0.3 g/L and cadmium of 0.03 g/L.

6 RISKS to HEALTH and SAFETY from INTENDED USE From personal exposure or hazardous reactions. Refer to OELs, flash points, etc., as appropriate. Are pregnant women, breast-feeding mothers especially at risk? Cadmium chloride is harmful if swallowed. Cadmium chloride may cause lung, liver and kidney damage. Cadmium chloride may cause severe eye, skin, respiratory tract and digestive tract irritation. Cadmium chloride may cause infertility and cause harm to the unborn child.

Cupric sulphate pentahydrate is toxic and harmful if swallowed. Cupric sulphate pentahydrate is irritating to eyes and skin. Cupric sulphate pentahydrate may impair fertility and cause harm to the unborn child.

Lead (II) nitrate may damage the central nervous system and kidneys on inhalation. Lead (II) nitrate may cause eye, skin and digestive tract irritation. Lead (II) nitrate may cause blood abnormalities and cancer. Lead (II) nitrate may combust above 200 C or in contact with the following materials: ammonium thiocyanate, potassium acetate, lead hypophosphite, aluminium, alkyl esters, carbon, hydroxylamine, phosphorus, phosphinates, sulphur, tin chloride. Lead (II) nitrate may impair fertility and cause harm to the unborn child.

Manganese sulphate monohydrate is harmful by inhalation, in contact with skin and if swallowed. Manganese sulphate monohydrate is irritating to eyes, skin and respiratory system. Manganese sulphate monohydrate is a possible mutagen and may cause irreversible effects.

Nickel chloride hexahydrate is toxic if swallowed. Nickel chloride hexahydrate may cause sensitisation by inhalation and skin contact. Nickel chloride hexahydrate is a possible carcinogen and there is a possible risk of irreversible effects.

Zinc sulphate heptahydrate is irritating to eyes, skin and respiratory system.

7 CONCLUSIONS ABOUT RISKS Is level of risk acceptable? Can risk be prevented or reduced by change of substance/procedure? Are control measures necessary? Yes. The amounts being weighed are very small and the final dilutions are very weak. Providing good practice is followed the risks are minimal.

8 CONTROL MEASURES Additional to Good Chemical Practice Proper labelling of storage containers which should be appropriately stored and, if necessary, transported in special containers. Protective gloves, a mask and a lab coat should be worn at all times. Soap, water and paper towels should be available.

9 INSTRUCTION/TRAINING Specify course(s) and/or special arrangements.

10 MONITORING Performance of control measures, None required unless list of chemicals or quantities change. Personal exposure Health Surveillance

11 WASTE DISPOSAL PROCEDURE See School Server for Approved Procedure Document on specific Chemical Waste Disposal. The aquarium water will go to drain with plenty of additional water.

12 REVIEW Enter the date or circumstances for review of assessment (maximum review interval 5 years) Review in three years time or in the event of a change to the protocol.

13 EMERGENCY ACTION TO CONTROL HAZARDS To stabilize situation eg spread absorbant on liquid spill; eliminate sources of ignition, etc. Carry out work wearing protective clothing; eliminate sources of ignition; ensure access to water and appropriate fire extinguishers. In the event of spillage, wear protective clothing, keep personnel not involved in practical work away from the area, mop up spillages with paper towels; ventilate area.

University emergency service tel: 44444; report accidents/incidents immediately.

TO PROTECT PERSONNEL Evacuation, protection for personnel involved in clean-up, Special First Aid For any of the listed salts or solutions in the event of: SKIN CONTACT: Drench the affected area with plenty of clean running water and soap for at least 15 minutes and until no chemical remains in contact with the skin. Remove contaminated clothing and shoes and obtain medical attention. Clothes and shoes must be washed before reuse. EYE CONTACT: Flush the eye with clean running water for at least 15 minutes occasionally separating the eyelids; obtain medical examination of the affected eye immediately. INGESTION: Do not make the casualty vomit; wash out the mouth with water if the casualty is conscious. In the case of lead (II) nitrate and cadmium chloride give the casualty 2-4 cupfuls of milk or water. Seek medical attention immediately. INHALATION: Remove the casualty from exposure to fresh air; rest and keep warm. If breathing is difficult give oxygen. If breathing has stopped give artificial respiration. In the case of cadmium chloride this must not be by mouth-to-mouth rather oxygen via a bag and mask. Seek medical attention.

TO RENDER SITE OF EMERGENCY SAFE Clean-up/decontamination Wearing protective clothing, gloves and eyeshield, mop up spillages and place contaminated waste in a sealed ‘hazardous waste’ labelled bag. This can be stored in the fume cupboard until collection. The area should be well ventilated and washed after material in the bag has been removed. Personnel not involved in cleaning up, should be kept well away from the area.

CONTACT : Norman Day TEL: 45474

10.10.00 * Prefix T is used for Teaching Assessment Number.

** Please include amount of chemicals used and how.

*** Hazdat No is the UNICOSHH datasheet report number.

Biosciences No is the Biosciences data sheet number.

UNICOSHH IS A CHEMICAL DATABASE ON THE HEALTH AND SAFETY UNIT SERVER. BIOSCIENCES DATA SHEETS ARE AVAILABLE IN THE SCHOOL SAFETY OFFICE.