AnS 214 Review Session 3 Friday 9/4, 11am

A) Oxygen Exchange – use the diag. to answer the following. 1) Fill in the blanks on the diagrams to the left. 2) Reproduce the entire reaction for the conversion of CO2 to bicarbonate below.

______+______+ _____

3) At the tissue level, ______leaving the cell can either become dissolved as gas in the blood stream, combine with ______to form carbamino compounds, or react with ______in the cell to form ______. This product can spontaneously dissociate to form ______and ______. The smaller of these two products replaces ______on the oxyhemoglobin the cell was carrying, turning it into deoxyhemoglobin. This displaced molecule then diffuses into the ______down its ______gradient to fuel cellular respiration.

- 4) HCO3 is a charged particle. This is the primary form in which ______travels in the bloodstream, but originates within the RBC. Going off of this information, explain the significance of chloride shift in the RBC.

5) What is the full name of the enzyme catalyses the reaction of water and carbon dioxide, and the reverse reaction involving carbonic acid?

6) In a paragraph similar to #3, explain how the bicarbonate from the bloodstream is turned into carbon dioxide, and why it then enters the lungs.

7) What is the origin of the H+ ion that combines with bicarbonate to form carbonic acid? B) Hemoglobin dissociation curves 1) Fill in the banks of the leftmost diagram. 2) Define “% saturation of hemoglobin”.

3) a. What is the % saturation of hemoglobin at pO2 100? Blood with this pO2 is most likely located at what tissue?

b. What is the % saturation of hemoglobin at pO2 40? Blood with this pO2 is most likely located at what tissue?

c. What accounts for the difference in % oxygen saturation of blood at these two organ levels?

4) In your own words describe what the center and right diagrams state about the dissociation of oxygen from hemoglobin as a function of a. body temp

b. pH

5) Using the information in part A of this worksheet, explain WHY hemoglobin is more likely to expel oxygen at the tissue level during exercise? Hint: look at the consequences of CO2 entering the RBC.

C) Avian respiration Compare mammalian and avian respiratory systems by filling in the table below. Mammals Birds Lung type Order of air flow

# of respiratory cycles (insp. + exp.) needed to move 1 volume of air through lungs Expiration is...... Amount of dead space Gas exchange occurs in.... Exchange efficiency Respiration rate Tidal volume