Biology Genetics Review Name ______
1. Who is the “Father of Genetics”? ______
Match the definition with the appropriate Mendelian Law: 2. Pairs of alleles separate in meiosis, and each gamete A. Rule of Dominance receives one allele of each pair B. Law of Segregation 3. One trait is dominant over another, if the dominant trait C. Law of Independent Assortment is present the other will be hidden 4. Sometimes traits disappear then reappear in a new generation showing chromosomes are separated independently of one another
MONOHYBRID CROSSES In mice, Brown fur (B) is dominant to white fur (b). 5. What is the genotype of a homozygous dominant mouse? ______6. What is the genotype of a homozygous recessive mouse? ______7. What is the genotype of a heterozygous mouse? ______8. Which genotypes could represent a brown mouse? BB Bb bb
9. Which genotype must represent a white mouse? BB Bb bb
10. Cross a white mouse with a heterozygous brown mouse. What is the white mouse’s genotype: ______What is the heterozygous brown mouse’s genotype: ______Now, create the punnett that shows the crossing of these two mice and show genotype and phenotype percentage possibilities for their offspring.
Genotypes: Phenotypes: BB: ______Brown: ______Bb: ______White: ______bb: ______
11. Cross two heterozygous brown mice. What is the genotype of the heterozygous female: ______What is the genotype of the heterozygous male: ______Now, create the punnett that shows the crossing of these two mice and show genotype and phenotype percentage possibilities for their offspring. Genotypes: Phenotypes: BB: ______Brown: ______Bb: ______White: ______bb: ______
12. If I flip a coin, what are my chances of getting heads? ______Tails? ______13. If a woman gives birth to a child, what are the chances she will have a boy? ______Girl? ______14. Mrs. Davis’ grandparents gave birth to 6 daughters. If they were still having kids, what is the chance that their next child would have been a girl? (Be careful about this…) ______
DIHYBRID CROSSES Some genes are inherited together and can be shown in a dihybrid cross. 15. In plants green peas (G) are dominant to yellow (g), and rough texture (R) is dominant to smooth (r). If a male parent plant has the genotype GgRr, what possible allele mixtures could be in the sperm of the parent for these two genes? Complete the Punnett below then fill in the sperm with allele combinations. Transfer the genotype from the punnett to the sperm picture and write underneath the sperm the phenotype of the genes it is carrying. The first one has been done for you.
G g
16. In apple trees, having apples (A) is dominant to not having apples (a) and having branches (B) is dominant to not having branches (b). Look at the dihybrid cross below. What are the genotypes and phenotypes of the squares labeled? The first one has been done for you as an example.
Genotypes: Phenotypes: a. AABb A. Apples, Branches b. ______B. ______c. ______C. ______d. ______D. ______18. Jane has red hair (h) but her parents have brown hair (H). What must her parent’s genotypes be in order for her to have red hair? 19. A mouse has 8 babies. 4 of the babies are black and 4 are white. What must the parent’s genotypes be in order to produce this litter of babies?
PEDIGREES Use the pedigree below to answer the questions. This pedigree is for red hair which is recessive and is NOT sex-linked. Brown hair (H) is dominant to red hair (h).
20. What is the gender of person II-1? ______21. What is the gender of person II-2? ______22. How many children did II-2 and II-3 have? ______23. How many sons did I-1 & 1-2 have? ______24. What is the genotype of person labeled I-2? ______25. What is the genotype of the person labeled I-4? ______26. What is the genotype of person II-2? ______(You must look at the person’s children to figure this out) 27. What is the genotype of person II-3? ______(You must look at the person’s children to figure this out) 28. If person III-3 marries a person who is heterozygous for hair color, what are the possible hair colors seen in their kids? What is person III-3’s genotype? ______What is a heterozygous person’s genotype? ______Put these two genotypes around the Punnett to determine hair color possibilities for their kids.
INCOMPLETE DOMINANCE In flowers, red petal color (RR) is incompletely dominant to white petal color (R’R’) producing a new phenotype of pink petal color (RR’). 29. Cross a red flower with a white flower and show genotypes and phenotypes of offspring.
Genotypes: Phenotypes: RR ______Red- ______RR’ ______Pink- ______R’R’ ______White- ______
30. Cross two pink flowers and show genotypes and phenotypes of offspring.
Genotypes: Phenotypes: RR ______Red- ______RR’ ______Pink- ______R’R’ ______White- ______
CODOMINANCE In chickens, black feathers (BB) is codominant to white feathers (WW) creating a new phenotype of Black and White Checkered feathers (BW). 31. Cross a white feathered chicken with a black and white checkered chicken and show genotypes and phenotypes.
Genotypes: Phenotypes: BB ______Black ______BW ______Black & White- ______WW ______White- ______32. Cross two black and white checkered chickens and show genotype and phenotypes.
Genotypes: Phenotypes: BB ______Black ______BW ______Black & White- ______WW ______White- ______
MULTIPLE ALLELES 33. Fill in the chart below with the possible genotypes of the blood types listed. PHENOTYPES GENOTYPES Blood Type A Blood Type B Blood Type AB Blood Type O
34. Would you say a person with a genotype of AA is homozygous or heterozygous? ______35. Would you say a person with a genotype of AO is homozygous or heterozygous? ______36. Is blood type AB an example of incomplete dominance or codominance? ______37. Which blood type seems to be more recessive- A, B, or O? ______38. Cross a parent with O blood with a parent with AB. What are the possible blood types for their kids?
Blood Phenotypes: ______39. Cross a parent with BB blood with a parent with OO blood. What are the possible blood types for their kids?
Blood Phenotypes:
______
40. Cross a parent with BO blood with a parent with OO blood. What are the possible blood types for their kids?
Blood Phenotypes:
______
41. Suppose a mother with A blood produced a child with O blood. (The father is OO), what genotype must the mother be to produce a child with O blood? SEX-LINKED TRAITS Sex linked traits are found on the X chromosome. Look at the chromosomes shown to the right. 42. Which pair belongs to a girl? ______43. What is a girl’s genotype? ______44. Which pair belongs to a boy? ______45. What is a boy’s genotype? ______46. The band across the tall chromosomes in both pictures represents an allele for a sex-linked trait. What is different about the bands on the boy’s chromosomes? ______47. Can a boy be a carrier of a sex-linked trait? ______Why or why not? ______Look at the Punnett to the right. Do boys get their X’s from their moms or dads? ______
48. Who gives a boy his sex-linked trait/disorder- his mom or dad? ______
Hemophilia (h) is a recessive sex-linked blood disorder. Answer the following questions based on this information. The first one has been done for you. 49. What is the genotype of a homozygous normal female? X H X H 50. What is the genotype of a heterozygous female? ______51. What is another name for a heterozygous female? ______52. What is the genotype of a homozygous recessive female that has hemophilia? ______53. What is the genotype of a normal male? ______54. What is the genotype of a hemophiliac male? ______55. Cross a homozygous dominant female with a hemophiliac male. Answer the questions below
a. What are the chances of getting a CHILD with hemophilia? ______b. What are the chances of getting a GIRL that is a carrier? ______(remember, you have to cover up the boys boxes, to answer questions about girls only)
56. Choose a male and female offspring from the Punnett Square above in question 52 and mate them. Use a Punnett square to show the results of their offspring. Answer the questions that follow. a. What are the chances of getting a CHILD with hemophilia? ______b. What are your chances of getting a BOY with hemophilia? ______(remember, you have to cover up the girls boxes, to answer questions about boys only) c. What are the chances of getting a GIRL that is a carrier? ______
57. What is the genotype of person I-1? ______58. What is the chance of person I-1 passing the disease to their offspring? ______59. Suppose person II-2 and II-3 have another child. What is the chance they will have a GIRL with hemophilia? (Do a Punnett) ______60. What is the chance they will have a CHILD with hemophilia? ______61. Other than looking at the title of the picture, how else would you have known this pedigree was for a sex-linked disorder? MUTATIONS & DISORDERS Match the mutation name with the picture. 62. Insertion 63. Deletion 64. Duplication 65. Inversion
Match the type of mutation to the picture. 66. Point mutation 67. Frameshift 68. nondisjunction Match the disorder to its description. 69. Child cannot drink milk b/c he can’t break down phenylalanine A. Klinefelters 70. Person has abnormal shaped red blood cells, severe pain & clots B. Cystic fibrosis 71. Person’s sex chromosomes are XXy C. Sickle Cell 72. Person has mucus build up in lungs and digestive system D. PKU
Match the disorder to its description. 73. Child has fat build up in nerve cells, loses ability to function, dies before age 8 A. Turners 74. Adult male loses feeling in arms legs, dies before age 40 B. Achondroplasia 75. Child born with shortened arms and legs, normal head & chest region C. Huntington’s 76. Female has sex chromosomes XO, webbed neck, mild mental deficiency D. Tay Sachs Disease
Use the karyotype picture to the right to answer the following questions: 77. Is this person a boy or girl? ______78. Circle the sex chromosomes. 79. What are all the other chromosomes called? ______80. Is the person in the karyotype to the right a boy or girl? ______81. This person is not normal. Look over the chromosomes and find the abnormality. What genetic disorder does this person have? ______82. What type of mutation causes this genetic disorder? a. Point mutation b. Frameshift mutation c. Nondisjunction