Christopher J. Potter, Ph.D

Christopher J. Potter, Ph.D. The Johns Hopkins School of Medicine The Solomon H. Synder Department of Neuroscience Center for Sensory Biology 855 N. Wolfe Street, 434 Rangos Building Baltimore, MD 21205 Phone: (443) 287-4151 [email protected] http://web1.johnshopkins.edu/potterlab/

EDUCATION: Ph.D. Genetics 2002 Yale University New Haven, Connecticut Thesis Advisor: Tian Xu, Ph.D.

B.A. Molecular and Cell Biology with Honors 1996 University of California at Berkeley Berkeley, California

RESEARCH EXPERIENCE: Assistant Professor, Dept. of Neuroscience March 2010- Johns Hopkins University, Center for Sensory Biology Postdoctoral Fellow, Laboratory of Liqun Luo, Ph.D. July 2002-March 2010 Stanford University, Dept. of Biology Graduate Student, Laboratory of Tian Xu, Ph.D. June 1997-June 2002 Yale University School of Medicine, Dept. of Genetics Undergraduate Student, Laboratory of Steven Beckendorf, Ph.D. June 1994-May 1996 UC Berkeley, Dept. of Molecular and Cell Biology

FELLOWSHIPS AND AWARDS: NIDCD RO1 Grant 2013-2018 Whitehall Foundation Grant 2011-2014 Damon Runyon Cancer Research Fellowship 2003-2006 Outstanding Undergraduate Geneticist Award, UC Berkeley 1996

PUBLICATIONS: Potter, CJ (2014) Stop the Biting: Targeting a Mosquito’s Sense of Smell (review), Cell 156:878- 881. Ronderos, DS, Lin, C-C, Potter, CJ, and Smith, DP (2014) Farnesol-Detecting Olfactory Neurons in Drosophila. Journal of Neuroscience 34:3959-3968. Liang, L, Li,Y, Potter, CJ, Yizhar, O, Deisseroth, K, Tsien, RW, and Luo, L (2013) GABAergic Projection Neurons Route Selective Olfactory Inputs to Specific Higher Order Neurons. Neuron 79:917-931. Potter, CJ Page 2

Subedi, A, Macurak, M, Gee, ST, Monge E, Goll, MG, Potter, CJ, Parsons, MJ, and Halpern, ME (2013) Adoption of the Q transcriptional regulatory system for zebrafish transgenesis. Methods, http://dx.doi.org/10.1016/j.ymeth.2013.06.012. Gao,XJ, Potter, CJ, Gohl, DM, Silies, M, Katsov, AY, Clandinin, TR, and Luo, L (2013) Aversive Chemotaxis Engages Specific Motor Patterns and Executive Circuits in Drosophila. Current Biology, 23:1163-72. Wei, X, Potter, CJ, Luo, L, and Shen, K. (2012) Controlling Gene Expression with the Q Repressible Binary Expression System in Caenorhabditis elegans. Nat Methods 9:391-395. Sweeney, LB, Chou,YH, Wu, Z, Joo, W, Komiyama, T, Potter, CJ, Kolodkin, AL, Garcia, KC, and Luo, L. (2011) Secreted Semaphorins from Degenerating Larval ORN Axons Direct Adult Projection Neuron Dendrite Targeting. Neuron 72: 734-747. Potter, CJ and Luo, L. (2011) Using the Q system in Drosophila melanogaster. Nat. Protocols 6:1105-1120. Gohl, DM, Silies, MA, Gao, XJ, Bhalerao, S, Luongo, FJ, Lin, CC, Potter, CJ, and Clandinin, TR. (2011) A Genetically Convertible Enhancer Trap Platform For Directed Combinatorial Dissection Of Gene Expression Patterns. Nat Methods 8(3):231-237. Potter, CJ*, Tasic, B*, Russler, EV, Liang, L, and Luo, L. (2010) The Q System: A Repressible Binary Expression System for Transgene Expression, Lineage Tracing and Mosaic Analysis. Cell 141:536-548. *Denotes equal contribution. Potter, CJ and Luo, L. (2010) Splinkerette PCR for Mapping Transposable Elements in Drosophila. PLoS ONE 5(4):e10168. Hong W, Zhu H, Potter CJ, Barsh G, Kurusu M, Zinn K, and Luo L. (2009) Leucine-rich repeat transmembrane proteins instruct discrete dendrite targeting in an olfactory map. Nature Neuroscience, 12:1542-1550. Berdnik, D, Fan, AP, Potter, CJ and Luo, L. (2008) microRNA Processing Pathway Regulates Olfactory Neuron Targeting. Current Biology 18:1754-9. Potter, CJ and Luo, L. (2008) Octopamine Fuels Fighting Flies. Nature Neuroscience 11:989-90. Jefferis, GSXE*, Potter, CJ*, Chan AM, Marin EC, Rohlfing T, Maurer, CR, Jr, and Liqun L. (2007) Comprehensive Maps of Drosophila Higher Olfactory Centers: Spatially Segregated Fruit and Pheromone Representation. Cell, 128:1187-1203. *Denotes equal contribution. Potter, CJ and Luo, L. (2003) Food for Thought: A receptor finds it ligand. Nature Neuroscience 6:1119-20. Potter, CJ, Pedraza, L, and Xu, T. (2002) Akt regulates growth by directly phosphorylating Tsc2. Nature Cell Biology. 4:658-665. Potter, CJ, Huang, H, and Xu, T. (2001) Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell, 105:357-68. Turenchalk, GS, Potter, CJ, Haddad, G. and Xu, T. (2001). Drosophila as a Genetic Model for Understanding Human Biology and Disease. Genetic Models in Cardiorespiratory Biology. Haddad, G. and Xu, T editors. Potter, CJ and Xu, T. (2001) Mechanisms of size control. Current Opinion in Genes and Development, 11:279-86. Potter, CJ, Turenchalk, GS, and Xu, T. (2000). The expanding role of Drosophila in cancer research. Trends in Genetics, 16:33-39. Potter, CJ Page 3

Huang, H*, Potter, CJ*, Tao, W, Li, D-M, Brogiolo, W, Hafen, E, Sun, H and Xu, T. (1999). PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development. Development 126, 5365-5372. *Denotes equal contribution.

INVITED TALKS: Olfactory Neural Circuits in Drosophila, National Institute of Health, June 2010. The Q repressible binary expression system for manipulating expression patterns, lineage tracing, and mosaic analysis. Janelia Farm Conference: Improving the Toolkit for Drosophila Neurogenetics, October 2009. Mapping olfactory perception in the Drosophila brain. CSH Neuronal Circuits: From Structure to Function, March 2006. Drosophila PTEN is a negative regulator of insulin signaling and cell size. 41st Annual Drosophila Research Conference, March 2000.

SELECTED ABSTRACTS Lin, C-C. Prigge, K, Preti, G, Potter, CJ. Food odors trigger Drosophila males to secrete a pheromone that guides female decisions. CSH Neurobiology of Drosophila, Oct 2013. Riabinina, O, Luginbuhl, D, Marr, E, Liu, S, Wu, M, Luo, L, Potter, CJ. Developing the second generation of Q-system reagents for genetic manipulations of Drosophila. CSH Neurobiology of Drosophila, Oct 2013. Lin, CC, St. Peter, D, Potter, CJ. Genetic dissection of odor representations encoded by fly projection neurons. Society for Neuroscience Annual Meeting, November 2011. Lin, CC, Potter, CJ. Olfactory neural networks required for an olfactory aggregation behavior. CSH Neurobiology of Drosophila, October 2011. Potter, CJ, Tasic, B, Russler, E, Luo, L. The Q repressible binary expression system for manipulating expression patterns, lineage tracing, and mosaic analysis. CSH Neurobiology of Drosophila, September 2009 Potter, CJ, Katsov A, Clandinin, T, Luo, L. Dissecting Projection Neuron Olfactory Codes Using A High Throughput Olfactory Behavioral Assay. Neurobiology of Drosophila, October 2007. Potter, CJ, Luo, L. Dissecting Projection Neuron Olfactory Codes in Drosophila. Janelia Farm Conference Insect Behavior: Small Brains, Big Functions, March 2007 Potter, CJ, Garg, R, Luo, L. Genetic Dissection of the Neural Circuitry Required for Olfactory Attraction. Neurobiology of Drosophila, October 2003. Potter, CJ, Huang, H, Xu, T. Drosophila TSC1 functions with dTSC2/gigas in the insulin signaling pathway to regulate cell growth, cell proliferation, and organ size. 42nd Annual Drosophila Research Conference, March 2001.

EXTERNAL RESEARCH SUPPORT Whitehall Foundation, 07/01/2011 to 06/30/2014 National Institutes of Health, NIDCD R01, 04/01/2013 to 03/31/2018