Scientific Programs

Scientific Programs Thursday, July 20, 2017 08:30 – 17:30 Meeting Registration – Hotel Lobby Society for Cryobiology Board of Governors Business Meeting – Room 509 18:30 – 21:00 Welcome Reception Friday, July 21, 2017 08:00 – 17:30 Meeting Registration – Hotel Lobby (Ground Floor) 08:00 – 08:30 Welcoming Address and Remarks – International Hall A Speakers: Societies’ Officials and Government leaders 08:30 – 10:10 Plenary Lectures#1: Fundamentals, advances and innovations in cryobiology, biopreservation, and biobanking – International Hall A Chair: Jason Acker and Brent Schacter Speaker 1: Jason Acker Topic: Cryobiology and its great impacts on the scientific research, modern agriculture, and precision medicine Speaker 2: Sebastian Eriksson Giwa (USA) Topic: Scaling up cryopreservation to large tissue systems: growing international support and the promise to transform medicine Speaker 3: Dayong Gao Topic: Freezing of living cells and tissues: a great challenge for biomedical scientists and engineers Speaker 4: Gregory Fahy Topic: Novel vitrification technology of tissues and organs: mechanisms, technology, and applications 10:10 – 10:20 Coffee Break – Hotel Corridor (Third Floor) 10:20 – 12:20 Plenary Lectures#1 (continue): Fundamentals, advances and innovations in cryobiology, biopreservation, and biobanking - International Hall A Chair: Erik Woods and Jim Vaught Speaker 5: Kelvin Brockbank (USA) Topic: Translating ice-free vitrification to human transplant sized tissue models Speaker 6: Xiaoxi Wei (USA) Topic: Cryoprotectants - the Blueprint of Ice Defense: Past, Present, and Future. Speaker 7: Xiaowen He Topic: - Development of advanced technology for optimal cryopreservation of human immune cells: from research to automated banking systems Speaker 8: Qiang Tian (USA) Topic: P4 Precision medicine and biobanking (P4: Predictive, Preventive, Personalized and Participatory)

12:20 – 13:20 Box Lunches Provided – Hotel Corridor (Third Floor) Cryobiology Editorial Board Meeting - Room 509 13:20 – 19:00 Plenary Lectures #2 – Best practices for biobanking and biorepositories: -International Hall A Chair: Zisis Kozlakidis and Hengjun Gao Speaker 10: Weizhi Ji

Topic: Nonhuman primate germ cell, embryo preservation and disease models

Speaker 11: Jing Liu

Topic: Precise Tumor Cryosurgery: Material, Device and Translational Medicine Speaker 12: Xun Xu

Topic: Gene bank and precision medicine

Speaker 13: Hengjun Gao (China)

Topic: Biobanking in China and its modern applications.

Speaker 14: Jim Vaught (USA)

Topic: Biobanking in the world: the past, present, and future

Speaker 15: Brent Schacter (Canada)

Speaker 16: Zisis Kozlakidis (UK)

Speaker 17: Kathy Sexton (USA)

Speaker 18: William Grizzle (USA)

Lectures from Speaker 11-14 will be focused on the following:

Topic: ISBER Best Practices: Biorepositories 101.

Lectures would be presented on Biorepositories 101, including best practices, which would educate the audience on the various issues that need to be recognized and dealt with in designing and managing a biorepository. The workshop will be useful to anyone thinking about or planning to establish a biorepository, as well as others who may have already started one, but would be interested in finding out how to further develop and expand their biorepository services. Part 1 of this workshop leads the audience through questions that should be asked and answered when considering the establishment of a human tissue biorepository. The answers to the questions will help them design the biorepository that is right for their needs. Part 2 delves more deeply into the details and issues of running and maintaining a biorepository. The workshop would cover and integrate the ISBER Best Practices.

Objectives:

• Gain insight about the various repository models available

• Learn what issues should be considered when designing and operating a repository

• Discuss the various types of services your repository might want to provide (without performing the investigator’s research for them!)

• Understand the importance of quality control and safety in the repository

• Gain a better understanding about the legal, ethical, and regulatory issues that may affect the repository • Understand the “nuts and bolts” of operating a repository

• Identify space and resources needed to begin a repository

• Understand the ISBER Best Practices

19:00 – 22:00 Poster Session #1 – International Hall B

Saturday, July 22, 2017 4 concurrent sessions/symposia in the morning 08:00 – 17:30 Meeting Registration – Hotel Lobby (Ground Floor) 08:30 – 10:30 Symposium #1- Advances in basic and applied cryobiology research – Dubai Hall Chair: Tamotsu Hoshino, Gregory Fahy and Dayong Gao Keynote Speaker 1 : Gang Zhao Topic:- TBD Keynote Speaker 2 : Igor Katkov Topic:- TBD Invited speaker 3: Xiaoming zhou (China) Topic: Heat transfer enhancement with microscale flows for vitrification of cells/tissues Invited Speaker 4: Jiaji Pan (TBD) Topic: - TBD

08:30 – 10:30 Symposium #2 – Modern technology of biopresevation and entrepreneur– Rome Hall Chair: Wendell Sun and Kelvin Brockbank Keynote Speaker 1: Wendell Sun Topic: TBD Invited Speaker 2: Xiaoxi Wei Topic: From The Arctic Ocean to Industry: X-THERMA’s Biomimetic Cryoprotective Nanomateria 08:30 – 10:30 Symposium #3 –Organizing, Implementing and Running Cryobanks for Clonally Propagated Plants – London Hall Chair: Barbara M. Reed Keynote Speaker 1 : Barbara M. Reed (USA) Topic: Why have a cryobank? The value of cryopreserved samples to humanity. Invited speaker 2: Svetlana Kushnarenko (Republic of Kazakhstan). Topic: Cryobanking clonally propagated plants in Kazakhstan: 15-year experience Invited speaker 3 : Monika Höfer (Germany) Topic: Cryopreservation as part of the conservation strategy for fruit genetic resources in Germany Invited speaker 4 : Xiaoling Chen (China) Topic: Cryobanking vegetative crops in National Crop Genebank of China Invited speaker 5 : Ranier Vollmer (USA) Topic: Evolution of Quality Standards in plant cryobanks - The International Potato Center as a case study 08:30 – 10:30 Session #1 – Development of novel cryoprotectants – Hong Kong Hall Chair: Lei Zhang and Ido Braslavsky Keynote Speaker: Lei Zhang Topic: Natural zwitterionic CPAs enable ultrarapid cell cryopreservation

10:30 – 10:45 Coffee Break – Hotel Corridor (Third Floor)

10:45 – 12:45 Symposium #2 (continue) –Modern technology of biopresevation and entrepreneur– Rome Hall Chair: Wendell Sun and Kelvin Brockbank Keynote speaker 1：Jing Liu Topic: Combined Cryosurgical System: Road from Fundamental Research to Industrial Translation

10:45 – 12:45 Symposium #4 –Cryopreservation of stem cells and immune cells– Dubai Hall Chair: Erik Woods, Renhe Xu and Tingyu Qu Keynote speaker 1: Erik Woods Topic: - Invited Speaker 2 : Wei Si Topic: - Vitrification Affects Global Gene Expression of Rhesus Macaque Mesenchymal Stem Cells Invited Speaker 3 : Kui Ma Topic: - TBD Invited Speaker 4 : Shen Ren Topic: - TBD

10:45 – 12:45 Session #2 –Vitrification: Basic Fundamentals, Practical Applications and Equipment – London Hall Chair: Igor Katkov and Gang Zhao Keynote Speaker: Igor Katkov Topic: TBD

10:45 – 12:45 Session #3 – Micro and nano technology for cryobiology – Hong Kong Hall Chair: Feng Xu and Adam Higgins Keynote Speaker 1: John Bischof Topic: Cryopreservation of bulk tissue with nanotechnology Keynote Speaker 2: Utkan Demirci（-） Topic: Microfluidic technologies for selection of cryopreserved sperm Invited speaker 3: Adam Higgins Topic: Microfluidic devices in blood cryopreservation

Invited speaker 5: Xiaohui Zhang（China） Topic: Microfluidics in Oocytes cryopreservation

12:45 – 13:30 Box Lunches Provided – Hotel Corridor (Third Floor) 3 concurrent sessions/symposia in the afternoon 13:30 – 15:30 Symposium #5 – Cryopreservation of reproductive cells and tissues – Dubai Hall Chair: Yunxia Cao, Keisuke Edashige and Yuksel Agca Keynote speaker1: Yuksel Agca Topic: Cryopreservation of reproductive cells and tissues. Invited Speaker 2: Keisuke Edashige Topic: A trial to vitrify 1-cell mouse zygotes with equilibrium vitrification Invited Speaker 3 : Bo Jin Topic: TBD Invited Speaker 4 : Zhiguo Zhang Topic: TBD

13:30 – 15:30 Symposium #6 –Animal cryobiology and conservation of endangered species – Rome Hall Chair: Tiantian Zhang and Wei Si Key note speaker 1: Tiantian Zhang Topic: Importance of cryopreservation of gametes of aquatic species in cryobanking and conservation Keynote Speaker 2: Wei Si Topic: Sperm cryopreservtion of rhesus and cynomolgus macaques 13:30 – 15:30 Session #4 –Biopreservation in the dry State – London Hall Chair: Willem Wolkers, Wendell Sun and Baolin Liu Keynote Speaker 1: Takashi Okuda (-) Topic: Anhydrobiosis Invited speaker 2: Ali Eroglu（Turkish）. Topic: Freeze-dried Sperm Invited speaker 3: Baolin Liu（China） Topic: Freeze-dried proteins Invited speaker 4: Miao Zhang (-) Topic: Use of trehalose to preserve DNA integrity in freeze-dried mammalian cells Invited speaker 5: Xiaoming He (USA) Topic：Nanoparticle-mediated intracellular delivery of trehalose Invited speaker 6: Zhang Shaozhi (China) Topic：Simulation of the freezing process in lyophilisation of human platelets 15:30 – 16:00 Coffee Break – Hotel Corridor (Third Floor) 16:00 – 18:00 Session #5 –Plant cryobiology and cryopreservation Chair: Haeng-hoon Kim and Barbara M. Reed Keynote Speaker 1：Diana Averill Bates Topic：Activation of apoptosis signalling pathways by reactive oxygen species Keynote Speaker 2：Barbara M. Reed Topic：In vitro physiological aspect in plant cryopreservation, including acclimation, antioxidants, post-culture, etc Invited Speaker 3：Shin-ichi Yamamoto Topic：Development of cryoplate-based vitrification methods and its application Invited Speaker 4：Haeng-hoon Kim Topic：A Systematic Approach to Develop Droplet-vitrification Procedure Invited Speaker 5：Elena Popova Topic：Frozenbeauty: The cryobiotechnology of orchid diversity Invited Speaker 6：Eva cellarova Topic：Conservation Strategies in the Genus Hypericum via Cryogenic Treatment; Exploring the Metabolic Stability of Engineered Hairy Roots after 16 Years Maintenance 16:00 – 18:00 Symposium #7 –Biobank and precision medicine Chair: Hengjun Gao and Yiwu He Keynote Speaker: Qingsong Liu Topic: TBD 16:00 – 18:00 Symposium #8 –Cryopreservation of blood cells and blood products Chair: Jason Acker and Zhong Liu – Rome Hall Chair: Jason Acker and Zhong Liu Keynote speaker 1: TBD Topic: TBD Invited Speaker 2: Xilin Ouyang Topic: TBD 18:00 – 20:00 Poster Session #2 – International Hall B Sunday, July 23, 2017 08:00 – 17:30 Meeting Registration – Hotel Lobby (Ground Floor) 3 concurrent sessions/symposia/workshops in the morning 8:30 – 10:30 Session #6 – Fertility Cryopreservation – Dubai Hall Chair: Yuksel Agca, Gang Zhao and Bo Jin

8:30 – 10:30 Session #7 – Peter L. Steponkus Crystal Award Competition Presentations – Rome Hall Chair: James Benson 8:30 – 10:30 Session #8 – Precise Cryotherapy and Hybrid Tumor Treatment – London Hall Chair: Shaozhi Zhang and Zhongshan Deng

10:30 – 10:45 Coffee Break – Hotel Corridor (Third Floor) Session #9– Bio-inspired cryopreservation – Dubai Hall Chair: Wei Rao and James Benson 10:45 – 12:45 Keynote Speaker 1: Jianjun Wang (China) Topic: AFP mimetics for cryopreservation of cells and tissues Invited speaker 2: Jie Yan（China）. Topic: L-proline: a highly effective cryoprotectant for mouse oocyte vitrification Invited speaker 3: Ziqiao Sun（China） Topic: A novel cryotherapy of loading micro-nano particles by mixing saline-alkaline solution in vivo. Invited speaker 4: Mengjia Dou（China） Topic: An amino acid addition enables low-CPA human mesenchymal stem cell vitrification 10:45 – 12:45 Session #10 –Tribute to Prof. TC Hua –Dubai Hall Chair: Baolin Liu and Zhaohua Chang

10:45 – 12:45 Session #11– Clinical Delivery of Regenerative Medicines –London Hall Chair: Ali Eroglu and Yuksel Agca Invited speaker 1: Erik J. Woods (USA) Topic: Current practices and potential improvements of stem cell banking Invited speaker 2: Ali Eroglu (Turkish) Topic: Clinical-grade cryopreservation of human stem cells Invited speaker 3: Yoshiaki Nakamura (Japan) Topic: Germ cell transplantation for preservation of avian and mammalian genetic resources Invited speaker 4: Shinsuke Seki (Japan) Topic：Conservation of medaka bio-resources by cryopreservation of germ cells 12:45 – 13:30 Session #12 - Box Lunches Provided – Conference hall 13:30 – 17:30 ICYR Activities 16:30 - 17:30 Session #13 - Cryo2018 Planning Meeting 17:30 – 18:30 Session #14 - Society for Cryobiology general meeting 19:00 – 21:00 Society of Cryobiology Gala Banquet / Awards Presentations – Cafeteria (Fourth Floor)