Chemo Charts: AML Consolidation MACE

CANTERBURY DHB (HAEMATOLOGY DEPARTMENT) Page 1 of 1 AML 15 – Consolidation - MACE DELIVER TO: HDW Patient Category: OSP Group: Doctors Name: Special Authority Number: Y J A P O 1 3 Z 1 2 3 4 5 6 7 NZMC Reg. No.: Antiemetics Weight kg Height cm

Ondansetron 8mg PO prior to amsacrine 2 Metoclopramide PO/IV 20mg QID PRN BSA m  Lorazepam 2mg PO Q6-12H PRN Dose Modified No Cycle 3 Neutrophils should be more than 1 X 109/L and platelets more than 100 X 109/L before starting ADMINISTRATION USE chemotherapy DR GIVEN DAY DATE TIME CHEMOTHERAPY AGENT DOSE ROUTE INSTRUCTIONS CHECK TIME SIGN BY 1 Amsacrine* 100mg/m2 mg IV In 500ml D5W over 1 hour Etoposide 100mg/m2 mg IV In 100ml 0.9S over 1 hour Cytarabine 200mg/m2 mg IV In ambulatory pump over 22 hrs 2 Amsacrine* 100mg/m2 mg IV In 500ml D5W over 1 hour Etoposide 100mg/m2 mg IV In 100ml 0.9S over 1 hour Cytarabine 200mg/m2 mg IV In ambulatory pump over 22 hrs 3 Amsacrine* 100mg/m2 mg IV In 500ml D5W over 1 hour Etoposide 100mg/m2 mg IV In 100ml 0.9S over 1 hour Cytarabine 200mg/m2 mg IV In ambulatory pump over 22 hrs 4 Amsacrine* 100mg/m2 mg IV In 500ml D5W over 1 hour Etoposide 100mg/m2 mg IV In 100ml 0.9S over 1 hour Cytarabine 200mg/m2 mg IV In ambulatory pump over 22 hrs 5 Amsacrine* 100mg/m2 mg IV In 500ml D5W over 1 hour Etoposide 100mg/m2 mg IV In 100ml 0.9S over 1 hour Cytarabine 200mg/m2 mg IV In ambulatory pump over 22 hrs Chemotherapy rounding: Amsacrine 5mg, etoposide <200mg 4mg, >200mg 20mg, cytarabine 20mg *Amsacrine must not be infused in 0.9S. Use D5W to flush prior to and after the infusion.

Authorised by Clinical Director: S Gibbons Pharmacist: B Harden 20 November 2007 D:\Docs\2017-12-29\0156daf1b2c856cc4f080ed24778f9a6.doc Ref: 2000

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