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CURRICULUM VITAE

Name: ALEXEI VERKHRATSKY

Date of birth: July 30, 1961

Nationality: UK/Ukraine

Title: MD, PhD, Dr. Sci.

Department: Professor of Neurophysiology Faculty of Life Sciences, The University of Manchester Michael Smith Building, Oxford Road, Manchester M13 9PT, UK e-mail: [email protected]

Current appointments: Professor of Neurophysiology

Higher Education and academic degrees: 1993: Doctor of Medical Sciences, Bogomoletz Institute of Physiology, Physiology, "Mechanisms of calcium signal generation in neurones and glial cells".

1983-1986: PhD, Bogomoletz Institute of Physiology: Physiology, "Tetrodotoxin sensitive ionic currents in the membrane of isolated cardiomyocytes"

1977 - 1983: MD, Kiev Medical Institute. Honours: 2003: Elected Member of Academia Europaea 2006 - 2013: Chairman of the Physiology and Medicine Section of the Academia Europaea; Member of the Council 2012: Elected member of Real Academia Nacional de Farmacia, Spain 2012: Research Award of German Purine Club 2012: Elected member of European Dana Alliance for the Brain 2013: Recipient of Dozor Visiting Scholar award, Ben Gurion University, Beer Sheva, Israel. 2013: Fellow of Japan Society for the Promotion of Science (JSPS). 2013: Elected member of Nationale Akademie der Wissenschaften Leopoldina (The German National Academy of Sciences Leopoldina) Membership of academic societies: The Physiological Society, UK (1994 - 2010) A.Verkhratsky - Curriculum Vitae 2

1994 - 2006 Member of International Committee 2002 - 2006 Member of Council Member of Council of Federation of European Physiological Societies, FEPS (2007 - ) American Society for Neuroscience, ASN (2011 - present) 2012 - present: member of membership committee Appointments: March 1st, 2002 - present: Professor of Neurophysiology at the Faculty of Life Sciences, The University of Manchester, Manchester, UK June 1st, 2002 - August 2004: Chairman of the Division of Neuroscience at the School of Biological Sciences, The University of Manchester, Manchester, UK July 1st 2001 - February 28, 2002: Reader in Neurophysiology at the School of Biological Sciences, The University of Manchester, Manchester, UK September 1999 - June 2001: Senior Lecturer at the School of Biological Sciences, The University of Manchester, Manchester, UK August 1995 - August 1999: Senior Research Scientist at the Department of Cellular Neuroscience in the Max-Delbrück Center for Molecular Medicine, Berlin December 1993 - August 1995: Head of the Research Group of Cellular Neuroscience, Bogomoletz Institute of Physiology, Kiev May 1993 - September 1993: guest scientist at the Department of Cellular Neuroscience of the Max-Delbruck Center of Molecular Medicine, Berlin May 1992 - August 1995: deputy director of the International Center of Molecular Physiology of the Ukrainian Academy of Sciences February 1992 - May 1992: guest scientist at the Research Group of Cellular Neurophysiology, Max-Plank Institute for Biophysical Chemistry, Göttingen 1990 - 1993: Senior Research Scientist at the Department of General Physiology of the Nervous System, Bogomoletz Institute of Physiology 1989 - 1990: Research Scientist in the Institute of Neurobiology, Heidelberg University 1986 - 1989: Junior Research Scientist at the Department of General Physiology of the Nervous System, Bogomoletz Institute of Physiology, Kiev Visiting/Honorary Appointments February 2014 - present: Head (Consultant) of the Laboratory of "Neuronal-Glial interactions in health and Disease", University of Nizny Novgorod, Russia September 2012 - present: Adjunct director of Achucarro Basque Centre for Neuroscience January 2011 - December 2013: Visitor Honorary Professor at Kyushu University, Fukuoka, Japan May 2010 - present: Visitor Professor/Consultant of the Basque Research Council (Ikerbasque) March 15th, 2007 - June 2010: Visitor Professor; Head of the Department of Molecular Neurophysiology, Institute of Experimental Medicine, ACSR, Prague, Czech Republic A.Verkhratsky - Curriculum Vitae 3

PROFESSIONAL AND ADMINISTRATIVE RESPONSIBILITIES

Editorial

Editor in Chief of Cell Calcium (2000 - ). Editor in Chief of Membrane Transport & Signalling - Wiley Interdisciplinary Reviews (2010 - ). Section Editor (Neuroscience) of Cell Death and Disease (2010 - ).

Member of Editorial board of Acta Pharmacologica Sinica (2005 - ). Member of Editorial board of Journal of Molecular & Cellular Medicine (2005 - 2009). Member of Editorial board of Acta Physiologica (Oxford) (2006 - ). Member of Editorial board of Pflugers Archiv European Journal of Physiology (2006 - ). Member of Editorial board of Glia (2008 - ). Member of Editorial board of Frontiers in Neuropharmacology (2009 - ). Member of Editorial board of Frontiers in Aging Neuroscience (2009 - ). Member of Editorial board of Purinergic Signalling (2010 - ). Member of Editorial Board of ASN Neuro (2011 - ). Member of Editorial Board of Frontiers in Neurodegeneration (2011 - ). Member of Editorial Board of Advances in Neurobiology (2011 - ). Member of Editorial Board of Neuroscience Bulletin (2011 - ). Member of Editorial Board of Translational Neurosciences (2012 - ). 2009 – Guest Editor of Trends in Neurosciences for the paper series on purinergic signalling in the Nervous system (with M. Abbracchio, G. Burnstock & H. Zimmermann). A.Verkhratsky - Curriculum Vitae 4

Organisation of Scientific Meetings

2013: Workshop "Astrocyte heterogeneity and transcriptome analysis" XI European meeting on Glial Cells in Health and Disease, Berlin, July 3 - 6, 2013 (together with Prof. M. Nedergaard). 2012: Purines 2012. International symposium “Purinergic signalling in new strategy of drug discovery”. Fukuoka, Japan, member of programme committee. 2011: Euroglia 2011 Meeting, Prague, Czech Republic: member of Programme Committee. 2011: Joint Meeting of the Turkish Society of Physiological Sciences and FEPS, Istanbul, Turkey, September 3 - 7; member of Organising and Programme Committees. 2011: Symposium “Molecular physiology of chemical transmission in neuronal-glial circuits”; Joint Meeting of the Turkish Society of Physiological Sciences and FEPS, Istanbul, Turkey, September 3 - 7, Organizer. 2011: Satellite meeting of International Society for Neurochemistry “Glial cells in (patho)physiology. Ljubljana, Slovenia, August 24 - 27, member of Programme Committee. 2011: International symposium “Reflections in Neurosceince. Integration and Disintegration of the Brain”, Bilbao, 13-14 June, Organizer (together with Prof. J.J.Rodriguez Arelliano). 2011: Colloquium “Physiological and Pathophysiological Signalling in Astroglial Circuits”; 42nd AnnualMeeting of the American Neurochemical Society, St. Louis, USA, 19 - 23 March, Organizer. 2010: COST B-30 Training School: “Cellular Neuropathology - In Vitro Models”; Kiev, Bogomoletz Institute of Physiology, 3 - 6 June, Organizer (together with Prof. O. Krishtal and Prof. R. Poshet). 2009: Joint meeting of FEPS and Slovakian Physiological Society, Ljubljana, 12 - 15 November; Member of the Organising Committee. 2009: International conference on “Purinergic signalling” dedicated to 80 years of ATP, Stockholm, Karolinska Institute, 17 – 19 September; Organizer (together with Prof. B. Fredholm). 2009: Symposium “Calcium and Cell Death”; International Union of Physiological Societies, Kyoto, Japan, July 29 – August 1. Organizer (together with Prof. P. Nicotera) 2007: 14th International Symposium on Chromaffin Cell Biology (with Prof. E. Carbone & Prof. A. Nistri), Sestri-Levante, Italy, October 11 - 15, 2007. 2007: International Physiological Society Workshop on "Molecular Physiology of Membrane Transport and Cell Excitability", Yaremche, Ukraine - 19 - 23 September 2007. 2007: Symposium " Molecular physiology of integration in neuronal-glial circuits" in the framework of Joint meeting of The Slovak Physiological Society, The Physiological Society and The Federation of European Physiological Societies (with Prof. E. Sykova), Bratislava, September 13, 2007. 2007: Symposium "Functional role of Bergmann glia - Purkinje cell signalling" in the framework of VIII th European Meeting "Glial cells in health and disease" (with Dr. F. Kirchhoff), London, September 5, 2007. 2007: International symposium on "Calcium Channels and Transporters" (with R.M. Case, D. Eisner, A. Gourney, O. Jones and S. Muallem), Manchester June 6 - 9, 2007. A.Verkhratsky - Curriculum Vitae 5

2007: Academia Europaea International Symposium “Molecular and Cellular mechanisms of Tissue Damage and Repair” (with Prof. P. Nicotera and Prof. O.H. Petersen), Heidelberg, March 1 - 4, 2007 2006: Academia Europaea International Symposium “25 Years of Giga-Seal Patch Clamping” (with Prof. O.H. Petersen), Heidelberg, March 30 - April 1, 2006 2006: Symposium in the framework of Joint meeting of German Physiological society and FEPS “Purinergic transmission in the CNS” (with Prof. A. North), Munchen, March 27, 2006. 2005: Joint Symposium of Societa Italiana di Fisiologia and The Physiological Society “I segnali di Calcio” (in the framework of 56 Annual Meeting of Italian Physiological Society), organizer (mutually with E. Carbone), Palermo, September 27, 2005. 2005: Academia Europea International workshop on "Reactive Oxygen Species", organiser (mutually with O.H. Petersen and A. Spat), Heidelberg, March 9 - 12, 2005. 2005: Physiological Society International Workshop in Cardiovascular Physiology "Ion Channels: From Physiology to pathology", organiser (mutually with J. Lopez-Barneo), Seville, February 7 - 9, 2005. 2004: Physiological Society International Workshop in Cardiovascular Physiology "Signal transduction in cardio-vascular system", organiser (mutually with D.A. Eisner, S. Wray & A. Beresevich), Warsaw, May 13 - 16, 2004. 2004: Academia Europaea International workshop on "Brain Plasticity: From Neurobiology to Neurology", organiser (mutually with O.H. Petersen), Heidelberg, March 4 - 6, 2004. 2003: Symposium in the framework of VIth IBRO Congress, "Endoplasmic reticulum as neuronal signalling organelle" organiser (mutually with Prof. O.H. Petersen), Prague, July 14, 2003. 2003: Symposium in the framework of 3rd FEPS congress, "Calcium signalling and neuronal-glial interactions", Nice, June 27 - July 2, 2003. 2002: International symposium "Molecular physiology of calcium signalling", organizer (mutually with Prof. O.H. Petersen and Dr. D. Riccardi), Liverpool, July 7 - 8, 2002. 2001: Symposium "Intracellular calcium stores" in a framework of BNA meeting, Harrogate, April 9, 2001. 2000: Physiological Society International Autumn School, Kiev, September 4 - 11, Organizer (mutually with Prof. D.A. Brown, London). 2000: International symposium on "Calcium as a molecule for cellular integration", Wye College, Kent, UK, July 21 - July 24, organiser. 2000: International symposium in the framework of 4th European glial meeting, Barcelona, May 24 - 27, organiser (mutually with Prof. A. Volterra, Milan). 1999: International symposium on "Neuronal calcium at the turn of millennium", December 22, Birmingham, organiser (mutually with Dr. E.C. Toescu, Birmingham). 1999: FEPS symposium "Calcium and neuronal ageing", Prague, June 30 - July 4. 1998: International symposium on "Glial cells membrane physiology", organiser (mutually with Prof. D. Attwell, London). A.Verkhratsky - Curriculum Vitae 6

1998: International symposium on "Calcium signalling in the Nervous System", organiser (mutually with Prof. O.H. Petersen, Liverpool). 1998: Symposium "Ion channels and neurotransmitter receptors in glia", organiser (in a framework of European Meeting on Glial function in Health and Disease; mutually with Dr. F. Kirchhoff) 1997: IUPS Workshop "Intracellular signalling", organiser, June 25 - 28, Kiev. 1996: Joint German-Ukraine meeting on "Intracellular signalling", organising secretary, September 30 - October 2, Berlin. 1995: International meeting on "Calcium and intracellular signalling" (supported by UNESCO), organising secretary, May 7 - 15, Kiev. 1994: International meeting on "Mechanisms of calcium signalling", organising secretary, June 20 - 28, Kiev. 1993: Joint meeting of The Physiological Society (UK) and Ukrainian Physiological society, organising secretary, October 1 - 7, Kiev. 1992: Joint Spain-USSR meeting on "Membrane biophysics", organising secretary, May 22 - 28, Kiev. 1991: Joint FRG-USSR meeting on "Biophysics of excitable membranes", organising secretary, October 1 - 7, Kiev.

Plenary lectures at international and national meetings

2014: Astrocytes in Health and Neurodegenerative Disease. A joint Biochemical Society / British Neuroscience Association Focused Meeting. "Astrogliopathology: a central element of neurodegenerative and neuropsychiatric diseases", London 28 - 29 April 2014. 2012: 21st Annual Puerto-Rico Neuroscience Conference, “Physiology and Pathophysiology of Neuroglia”, Puerto-Rico, December 1. 2012: Plenary lecture at 38th meeting of Turkish Physiological Society “Physiology of neuroglia”, Trabzon, September 25 - 29. 2012: Inaugural lecture at Real Academia Nacional de Farmacia, “Physiology and pathophysiology of Neuroglia”, Madrid, April 12. 2011: Key speaker at the “Neuroglia” workshop held in association with 10th national Meeting of the Turkish Neuroscience Society; Istanbul, 8 April. Lectures: “Where the thoughts dwell: History of Neuroscience and introduction into Neuroglia” “Cell Biology of Astroglia” “Glial Calcium Signalling” “Glial ionotropic receptors: Why Non-excitable Cells possess “Excitable” molecules?” “Glia in neuropathology with a Special Emphasis on Alzheimer’s Disease” 2011: Annual meeting of Sonderforschungsbereich 748 (“Neuronal and glial P2 receptors; molecular basis and functional significance”), Plenary Lecture: “Ionotropic ATP receptors in the neuronal- glial communication”; Leipzig, Germany, 14 - 15 March. A.Verkhratsky - Curriculum Vitae 7

2010: International conference dedicated to 30th anniversary of Acta Pharmacologica Sinica, Opening key lecture “Physiology and pathophysiology of neuroglia”, Shanghai, China, August 31 - September 1. 2009: XIII National Congress of the Italian Society for Neuroscience. Plenary lecturer: “Chemical transmission in neuronal-glial circuitry”. Milan, Italy, October 2 – 5. 2009: Satellite Symposium of the International Society of Neurochemistry “Glia as transmitter sources and sensors”, Plenary lecturer “Neuronal-glial and interglial interactions”, Shenyang, China, August 29 – September 1. 2009: ART Yorkshire Branch annual meeting, Plenary lecturer: “The role of glia in Alzheimer's disease”, Leeds University, January 21. 2008: Special plenary lecture at 6th FENS Forum, "Glial-neuronal circuits unify the reticular and neuronal theories of brain organisation", Geneva, July 12 - 16. 2005: Inaugural Annual Lecture of Federation of European Physiological Societies (FEPS) “Physiology and pathophysiology of the endoplasmic reticulum calcium store” delivered at Joint Meeting of The Physiological Society and FEPS, Bristol (UK), July 22 - 25. A.Verkhratsky - Curriculum Vitae 8

Invited lectures at international meetings

2014: International conference "Glutamate/GABA and neuro-glia-vascular interplay in norm and pathology", invited speaker "P2X and NMDA receptors mediate fast sodium signalling in astroglia, Krakow, Poland, May 21 - 24. 2014: 4th Annual Gladstone/DZNE Workshop "Cell and Organ Interactions in the Pathogenesis of Neurodegenerative Diseases", invited speaker "Astroglia in Alzheimer's disease", Bonn, Germany, May 11 - 13. 2014: Training School and International Research Conference "Astrocyte Intermediate Filaments (Nanofilaments) and Astrocyte Function in Health and Disease", invited speaker "Neuron-glia interactions in health and disease: what we know and would like to know", Gothenburg, Sweden, March 18 - 21. 2013: XVth Congress of the Italian Society of Neuroscience (S.I.N.S.); invited speaker: "Physiological role of microglia: shaping neural networks", Roma, Italy, October 3 - 6, 2013. 2013: 64th Congress of the Italian Physiological Society, Invited key speaker: "Astroglia function in ageing and Alzheimer’s disease", Portonovo di Ankona, Italy, September 18 - 20, 2013. 2013: FENS Featured Regional meeting, Invited speaker, "Neurological diseases as gliopathologies", Prague, Czech Republic, September 11 - 14, 2013. 2013: 38th FEBS Congress, Invited speaker "P2X and NMDA receptors mediate fast sodium signalling in cortical astroglia", St. Petersburg, Russia, July 6 - 11, 2013. 2013: XI European meeting on Glial Cells in Health and Disease, Invited speaker "Evolution, physiology and pathophysiology of neuroglia", Berlin, Germany, July 3 - 6, 2013. 2013: 5th Conference on Advances in Molecular Mechanisms Underlying Neurological Disorders (Joint conference of the European Society for Neurochemistry and the Biochemical Society", Invited speaker "Cross-talk between astrocytes and neurones: Astrocytes in physiology and pathophysiology", Bath June 23 - 26, 2013. 2013: 4th Annual Conference "Superresolution Microscopy", Invited speaker "History of Neurophysiology with emphasis on Neuroglia", Ljubliana, Slovenia, June 10 - 12, 2013. 2013: Astroglia-ECM Signalling and Neural Activity international conference and workshop (BM1001 COST ACTION), invited speaker, " ”Evolutionary roots, physiology and pathophysiology of astroglia”, Palermo, Italy, may 27 - 29, 3013. 2013: Physiology and Pathophysiology. Bioscience Birthday Symposium for Ole Petersen. Invited speaker: "Calcium and sodium signalling in astroglia", Cardiff, UK, 6 - 7 March. 2013: 3rd Venusberg Meeting on neuroinflammation. Mediators, Mechanisms, Clinics. Invited speaker: "Astrocytes in Alzheimer's disease", Bonn, Germany, February 28 - March 2. 2012: 4th Conference of Mediterranean Neuroscience Society, Invited speaker “Neuroglia: from brain homeostasis to Pathophysiology”, Istanbul, Turkey, September 30 - October 3. 2012: International symposium “Calcium signalling: Molecular mechanisms and Integrative Functions”, invited speaker (opening lecture), “Calcium and sodium microdomains in fast neuronal-glial signalling. Homburg/Saar, Germany, September 7 - 8. A.Verkhratsky - Curriculum Vitae 9

2012: 2nd Summer School of EduGlia, invited speaker “Neuroglia - Evolution of the Concept”, Margaux, France, August 25 - 27. 2012: Satellite symposium of FENS Forum 2012 “Multidisciplinary approaches to quantify astrocyte neuron signaling”, invited speaker “Ionotropic receptors and fast ion signalling drives neuronal- glial cross-talk at the level of individual synapse”, Barcelona, Spain, July 12 - 13. 2012: International symposium “Purine 2012 in Fukuoka; Purinergic signalling in new strategy of drug discovery”, invited speaker “ATP as a principal neuro-glial transmitter”, Fukuoka, Japan, May 31 - June 2. 2012: American Society of Neurochemistry Annual meeting; Pre-meeting workshop “Glial cells in (patho)physiology: Possible new targets for medical intervention”, invited speaker “Ionotropic receptors in physiology and pathophysiology of astroglia”, Baltimore, USA, March 3. 2012: International Neuroscience Symposium 2012 “Neuronal and glial signalling: From physiology to epilepsy”, invited speaker, “Physiology of astroglial neurotransmitter receptors “, Bonn, Germany, March 1 - 3rd 2012: International workshop “Physiopathplogy of Calcium Signaling”, invited speaker “Where the Thoughts Dwell: History of Neurosciences and Introduction Into Neuroglia” University of Occupational and Environmental Health, Kitakyushu, Japan, January 20. 2011: 6th International conference on Na+/Ca2+ exchange 2011, invited speaker “Sodium signalling in neuronal-glial communications”, Lacco Ameno, Ischia Island, Italy, October 1 - 5. 2011: 10th European meeting on Glial cells in health and disease, invited speaker for the introductory course, “Where the thoughts dwell: History of neuroscience and introduction into neuroglia”, Prague, Czech Republic, September 13 - 17. 2011: Joint Meeting of the Turkish Society of Physiological Sciences and FEPS, invited speaker “Chemical transmission in neuronal-glial networks”, Istanbul, Turkey, September 3 - 7. 2011: Joint Meeting of the Turkish Society of Physiological Sciences and FEPS, invited speaker “Calcium signalling in neuroglia”, Istanbul, Turkey, September 3 - 7. 2011: Satellite meeting of International Society for Neurochemistry “The glutamatergic synapse”, invited speaker “Neuronal-glial chemical transmission mediated by glutamate and ATP”, Heraklion, Crete, September 2 - 5. 2011: Satellite meeting of International Society for Neurochemistry “Glial cells in (patho)physiology.” invited speaker “Ionotropic glutamate receptors and purinoceptors in astroglia” Ljubljana, Slovenia, August 24 - 27. 2011: Joint conference of the Czech and Slovak Neuroscience Societies, invited speaker: “Ionotropic receptors in astroglia”, Smolenice Castle, Slovakia, May 18 - 21. 2011: The 21st National Biennial Meeting of the British Neuroscience Association, invited speaker: “Neuroglia in neurodegenerative diseases”, Harrogate, UK, April 17 - 20. 2011: 42nd Annual Meeting of the American Neurochemical Society, invited speaker “Physiology and pathophysiology of astroglia: An overview” St. Louis, USA, 19 - 23 March. 2011: International Workshop “Calcium Dynamics in Cells”, invited speaker “Glial ionotropic receptors and calcium signalling” Kitakushu, Japan, January 23. A.Verkhratsky - Curriculum Vitae 10

2010: Annual general Meeting of Academia Europaea, invited speaker “Neuroglia is not a passive support for neurones”, Leuven, Belgium, September 8 - 11. 2010: 11th Meeting of European Calcium Society, invited speaker “Calcium signals provide the substrate for glial excitability”, Warsaw, September 6 - 9. 2010: Symposium of the DFG-Priority Programme, “The role of neuroglia for the formation, function and plasticity of synapses”, invited speaker “Purinergic transmission in neuronal-glial networks” Kaiserslautern, Germany, August 26 - 29. 2010: Special symposium “Axon-glial interactions in the CNS” in conjunction with Summer meeting of The Anatomical Society, invited speaker “Neuroglia in neurodegenerative diseases”, Portsmouth, July 20 – 22. 2010: Max-Plank Society and University of Maribor; Research conference “Communicating Physiology”, invited speaker “Where the thoughts dwell: Physiology of neuronal glial networks”, Maribor, Slovenia, July 15 – 18. 2010: The BBRI/DZNE and Cell Death & Disease Conference (dedicated to 101st birthday of Rita Levi- Montalchini) “From Synapses to neurodegeneration”, invited speaker, “Neuroglial roots of neurodgeneration”, Rome, Italy, July 12-13. 2010: COST B-30 Training School: “Cellular Neuropathology - In Vitro Models”, invited speaker, "Astroglia in neurodegeneration", Kiev, The Ukraine, Bogomoletz Institute of Physiology June 3 - 6. 2010: Purines 2010 meeting “Adenine Nucleosides and nucleotides in biomedicine”, invited speaker "Physiology and pathophysiology of purinergic signalling in neuroglia", Tarragona, Spain, May 30 – June 2nd. 2009: 1a Giornata Scientifica del Dipartimento di Medicina Sperimentale e Scienze Biochemiche, invited key-speaker, “ATP as a neuro/gliotransmitter”, University “Tor Vergara”, Rome, Italy, December 21. 2009: Inaugural meeting of the UK Purine Club, invited speaker “Purinergic signalling in the CNS in neuronal and glial networks”, Sheffield, November 19. 2009: Joint Meeting of FEPS, Slovenian and Austrian Physiological Societies; invited speaker: “Dynamic calcium stores, calcium signalling and neurodegeneration”. Ljubljana, Slovenia, November 12 – 15. 2009: International symposium “Ligand-gated cationic channels and G protein-coupled receptors in the nervous system“, Invited speaker “Purinergic transmission in neuronal-glial networks”, Leipzig, Germany, October 7-9. 2009: VI International Cajal Club Meeting. “Camillo Golgi and modern neuroscience” Invited speaker “Signalling in neuronal-glial circuits: Role of glutamate and ATP transmission” Pavia, Italy, September 30 – October 1. 2009: International conference on “Purinergic signalling” dedicated to 80 years of ATP, Invited speaker “P2X mediated transmission in neuronal-glial networks” , Stockholm, Karolinska Institute, 17 – 19 September. 2009: 36th Congress of the International Union of Physiological Societies, Invited speaker “Endoplasmic reticulum Ca2+ homeostasis and neural cell disease and death”, Kyoto, Japan, July 29 – August 1. A.Verkhratsky - Curriculum Vitae 11

2009: Spring Hippocampal Research Conference, Invited speaker "Physiology and pathophysiology of neuroglia", Verona, Italy, June 14 ‐19. 2009: EU workshop on “CORTEX - Neuronal signalling”. Invited speaker: “Signalling mechanisms in neuronal-glial networks”, Prague, Institute of Experimental Medicine, June 3 - 5. 2009: European workshop on “Astrocyte-synapse interactions”. Invited speaker: “Chemical transmission in neuronal-glial circuits”, Strasbourg, European Doctoral College, January 23. 2008: Forth Annual Benoziyo Symposium on Neurodegeneration, invited Plenary speaker: “The keeper, the guardian, the killer: Glial cells in brain diseases” Weizmann Institute, Rehovot, Israel, September 21. 2008: Annual Meeting of Scandinavian Physiological Society; invited speaker: “P2X-mediated transmission in neuronal-glial networks”, Oulu, August 15 – 18. 2008: Special plenary lecture at 6th FENS Forum, "Glial-neuronal circuits unify the reticular and neuronal theories of brain organisation", Geneva, July 12 - 16. 2008: 1st Neurotek Research Symposium, invited Plenary speaker "Purinoreceptors in the CNS", Bilbao, July 4th. 2008: 52nd Canadian Federation of Biological Societies, invited speaker "Glia in neurodegeneration and Alzheimer disease", Winnipeg, June 17 - 20. 2008: International Symposium on "Frontiers in Physiology", invited speaker "Physiology of glial- neuronal circuits", Copenhagen, May 15-16. 2008: European Tissue Culture Society Meeting "Cell Death Mechanisms", invited speaker "Glial cells and brain diseases", Bristol, April 23rd. 2007: 6th Conference of the Czech Neuroscience Society, invited speaker "Glutamate-mediated neuronal- glial transmission", Prague, November 19 - 20, 2007. 2007: 14th International Symposium on Chromaffin Cell Biology, invited speaker "Calcium signalling in astrocytes", Sestri-Levante, October 11 - 15, 2007. 2007: Joint meeting of The Slovak Physiological Society, The Physiological Society and The Federation of European Physiological Societies, invited speaker "Calcium signals and integration in neuronal- glial networks", Bratislava, September 11 - 14, 2007. 2007: DiMI/EMIL European Summer school on Molecular imaging, invited speaker "Imaging of endoplasmic reticulum dynamics in living cells", Prague August 29 - 31, 2007. 2007: 31th Göttingen Neurobiologische Tagung, invited speaker "Quantal release of ATP in central synapses", Göttingen, March 29 - April 1. 2006: International conference of DFG special group on "The role of neuroglia for the formation, function and plasticity of synapses", invited speaker "NMDA receptors mediate neuronal-glial interactions in the cortex", Bonn, September 28-30. 2006: 2nd International Conference of Neuroscience Society of Romania, invited speaker "Physiology of neuroglia", Bucharest, August 31 - September 2. 2006: Plenary lecture at the Academy of Sciences of Hungary, "Glial neurobiology", June 12. A.Verkhratsky - Curriculum Vitae 12

2006: First Montpellier International Calcium Conference, invited speaker “Integration in neuronal-glial circuits: Calcium takes the leading route”, Montpellier, April 10. 2006: Academia Europaea International symposium, invited speaker “25 years of Giga-seal patch- clamping”, invited speaker “Patching the glial cells - 150 years of understanding the glial function”, Heidelberg, March 30 - April 1. 2006: Joint meeting of German Physiological Society and FEPS, invited speaker “Quantal release of ATP at cortical synapses”, Munchen, March 26 - 29. 2006: Alzheimer Research Trust Network Conference, invited speaker “Endoplasmic reticulum calcium homeostasis and Alzheimer disease”, Manchester, March 15 - 16. 2005: International Symposium on Neuroscience, invited speaker “Endoplasmic reticulum and neuronal calcium signalling”, Timisoara, October 14 - 15. 2005: Joint Symposium of Societa Italiana di Fisiologia and The Physiological Society “I segnali di Calcio”, invited speaker “Calcium dynamics and neuronal death”, Palermo, September 27. 2005: 20th Meeting of International Society for Neurochemistry, invited speaker “Calcium homeostasis in the neuronal ER: General principles and implications for physiology and pathophysiology”, Innsbruck (Austria), August 21 - 26. 2005: 82nd Annual Meeting of The Physiological Society of Japan, invited speaker “Endoplasmic reticulum and neuronal calcium signalling”, Sendai (Japan), May 18 – 20. 2005: 14th International Symposium on “Calcium and Calcium Binding Proteins in Health and Disease”, invited speaker “Endoplasmic reticulum and neuronal calcium signalling”, Banff (Canada), April 5 – 10. 2005: INSERM/College de France International Meeting on “Aspects dynamiques des interactions neurone-glie”, invited speaker “Neuroglial communications: role of electrical and chemical synapses” Paris, March 18. 2004: IBRO autumn school, invited speaker “Endoplasmic reticulum and calcium signalling”, Yalta, September 15 - 28. 2004: Physiological Society International Workshop in Cardiovascular Physiology "Signal transduction in cardio-vascular system", invited speaker "General physiology of endoplasmic reticulum calcium signalling", Warsaw, May 13 - 16. 2004: International workshop "Oscillations and waves in cells and cellular networks", invited speaker "Neuronal ER calcium signalling", Cargese, May 9 - 11. 2004: Academia Europaea International workshop on "Brain Plasticity: From Neurobiology to Neurology", invited speaker "Neuronal-glial circuits: An overview", Heidelberg, 4 - 6 March, 2004. 2003: International Workshop "Calcium release and cellular calcium signalling domains", invited speaker: "ER calcium dynamics in nerve cells", Marbella, Chile, Sept. 28 - Oct. 2. 2003: International Workshop in Neuroscience "Ischemia/Hypoxia in the Brain, invited speaker: "Physiological and pathophysiological relevance of ER calcium signalling. Bucharest, Sept. 23 - 25. 2003: The First International Conference of the National Neuroscience society of Romania, invited speaker: "Mitochondrial disfunction in diabetic sensory neuropthy", Bucharest, Sept. 26 - 27. A.Verkhratsky - Curriculum Vitae 13

2003: X Congreso de La Socieadad Espanola de Neurociencia, invited speaker: "ER calcium dynamics and neuronal signalling", Lleida, Sept. 6 - 9, 2003: VIth IBRO Congress, invited speaker: "Endoplasmic reticulum calcium store and neuronal signalling", Prague, July 10 - July 15. 2003: 3rd FEPS Congress, invited speaker: "Neurones and glia in cross-talk: Role of chemical and electrical synapses", Nice, June 27 - July, 2nd. 2003: Academia Europaea meeting "Obesity and diabetes"; invited speaker "Insulin-dependent regulation of mitochondrial function in neurones", Heidelberg, 6 - 9 March. 2002: European (INTAS) meeting on "Calcium, synaptic transmission and intracellular signalling"; Invited speaker "Endoplasmic reticulum and neuronal signalling" Turin, September 26 - 27. 2002: International symposium on "Molecular Physiology of Calcium Signalling", invited speaker: "Intra- ER calcium dynamics in nerve cells", Liverpool, July 8 - 9. 2002: IBRO Summer School "Mechanisms of synaptic transmission", invited speaker "ER as an integrative signalling organelle: Role in neuronal signalling", Kiev, June 16 - 18. 2002: 4th International congress of pathophysiology, invited speaker "The endoplasmic reticulum as integrating signalling organelle", Budapest, June 29 - July 5. 2002: Academia Europaea meeting "Calcium signalling", invited speaker "Intra-ER calcium dynamics in neurones", Heidelberg, March 7 - 10. 2001: 4th Conference of Czech Neuroscience Society; Invited speaker "Calcium dynamics in the ER lumen in neurones: ER as a calcium tunnel?" Prague October 26 - 27. 2001: BNA national meeting; Invited speaker "Calcium stores and calcium-induced calcium release in neurones", Harrogate, April 8 - 12. 2001: Academia Europaea meeting "Imaging of brain function", invited speaker "Calcium signalling and neuronal-glial communication", Heidelberg, March 15 - 17. 2000: NATO workshop on Cellular Signalling, Invited speaker "Calcium and glial function", Il Ciocco, April 22 - 26. 2000: UNESCO Summer Workshop "Intracellular signalling", Invited speaker "Neuronal calcium stores", Kiev, June 8 - 12. 1999: Annual meeting of the Society for Experimental Biology, Invited speaker "Synaptically induced signals in Bergmann glia: characterization and mechanisms", Edinburgh, March 25. 1998: Forum of European Neuroscience, satellite symposium XIII "Cellular compartmentation by the second messenger Ca in nervous system cells", invited speaker "Calcium signalling in glial subcompartments", Berlin, July 1. 1998: Forum of European Neuroscience, invited speaker "Ca2+ signalling between neurones and glia", Berlin, June 30. 1998: Symposium "Glial Cells and the Brain Interstitium", invited speaker "Glutamate-induced signalling in cerebellar Bergmann glial cells", Prague, June 22. 1998: Workshop on Theoretical Biophysics organized by Humbold University, Berlin, invited speaker "Calcium signalling in glial cells", Hiddensee, Germany. A.Verkhratsky - Curriculum Vitae 14

1997: Symposium "Cell Calcium Physiology", invited speaker "Calcium signalling in glial cells", Cambridge, UK.

2+ 1997: IUPS Workshop "Intracellular signalling", invited speaker "Calcium signalling in glia: [Ca ]i fluctuation as a form of glial excitability", Kiev, Ukraine. 1997: Symposium "Neurobiology of Ageing", invited speaker "Calcium signalling and neuronal ageing", Dublin, Ireland. 1997: EC School on "Mechanisms of intracellular signalling", invited speaker "Calcium signalling in glial cells", Liverpool, UK. 1997: International meeting dedicated to 100 years of "Pflugers Archiv", invited speaker "Mechanisms of glutamate-induced calcium signalling in Bergmann glial cells", Liverpool, UK. 1996: 1st Congress of German Neuroscience Society, invited speaker "Purinoreceptors in glial cells", Berlin, Germany 1995: Göttingen Neurobiologische Tagung, invited speaker, "Mechanisms of calcium signalling in glial cells", Göttingen, Germany. 1995: International meeting "Calcium and intracellular signalling", invited speaker "Calcium-stores in neurones", Kiev, Ukraine. 1995: International symposium "Calcium and ageing", invited speaker "Calcium signalling in aged cerebellar granule neurones in situ in acutely prepared slices", Heidelberg, Germany 1994: International meeting on "Physiology of glial cells", invited speaker "Calcium signalling in oligodendrocytes", Dresden, Germany 1994: International meeting "Mechanisms of calcium signalling", invited speaker "Calcium-induced calcium release in neurones", Kiev, Ukraine. 1993: Congress of the International Union of Physiological Sciences, invited speaker "Caffeine-induced calcium release in cerebellar Purkinje neurones", Glasgow, Scotland. 1993: New York Academy of Sciences Symposium on "Calcium hypothesis of ageing and Alzheimer's disease", invited speaker "Calcium currents and cytoplasmic calcium homeostasis in aged neurones", Washington, USA.

Seminars

1. "Neuroglia in ageing and Alzheimer's disease", College de France, February 2014, invited by Professor Christian Giaume. 2. "Physiology and pathophysiology of neuroglia", University of Nizhny Novgorod, January 2014, invited by Professor Victor Kazantsev. 3. "Astroglia in Alzheimer's disease", University of Kanazawa, November 2013, invited by Professor Hiroshi Kawasaki. 4. "General physiology of neuroglia", "Tor Vergata" University of Rome, October 4, 2013, invited by Professor Gerry Melino. A.Verkhratsky - Curriculum Vitae 15

5. "Neuroglia: Physiology and pathophysiology", Opening lecture for postgraduate education course in neuroscience, Neurocentre Magandie, University Bordeaux 2, September 2013, invited by Professor Stephane Oliet. 6. "Introduction into neuroglia: Evolution, definition, heterogeneity and general cell biology", Zlotowski special seminar series, Ben Gurion University, Beer Sheva, Israel, August 2013, invited by Professor Israel Sekler. 7. "Physiology and pathophysiology of astroglia", Zlotowski special seminar series, Ben Gurion University, Beer Sheva, Israel, September 2013, invited by Professor Israel Sekler. 8. "Neuroglia: Evolution, physiology and pathology with a particular emphasis on neurodegeneration", Department of Physiology, Tubingen University, March 2013, invited by Professor Olga Garaschuk. 9. "Physiology and pathophysiology of astroglia", Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden, February 2013, invited by Professor Balazs Gulyas. 10. "The role of astrocytes in Alzheimer's disease", Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden, February 2013, invited by Professor Agneta Norenberg. 11. "Astrosytes in neurodegenerative diseases". RIKEN, Tokyo, Japan, January 2013, Invited by Dr. Alexey Semyanov. 12. “ Astrocytes: Neurotransmitter receptors, Sodium signalling, Ageing and Neurodegeneration”, Biomedicum Helsinki 1, University of Helsinki, December 2012, invited by Dr. Leo Khiroug. 13. “Ionotropic receptor channels in glial cells”, Universidad Central del Caribe, Puerto-Rico, December 2012, invited by Professor Serguei Skatchkov. 14. “ Physiology and pathophysiology of astroglia”. Cardiff University, May 2012, invited by Professor Vincenco Crunelli. 15. “ Astroglia in neurodenegeration”, Trinity College, Dublin, February 2012, invited by Professor Marina Lynch. 16. “Physiology and pathophysiology of neuroglia”, University of Oxford, December 2011, invited by Dr. Maike Glitsch. 17. “ Neuronal-glial chemical transmission” Key lecture at the Glia day, November 2011, Center of Translational Medicine, University of Rochester, invited by Professor Maiken Nedergaard. 18. “ Astroglia in neurodegenrative diseses”, Neurosceince Center, University of Helsinki, November 2011, Invited by Dr. Leo Khiroug. 19. “ Astroglia in neurodegeneration with particular emphasis on Alzheimer’s disease”, College de France, September 2011, invited by Prof. Christian Giaume. 20. “ General physiology of neuroglia” University of Kentucky, Lexington, March 2011, invited by Professor Phil Landfield and Dr. Olivier Tibault. 21. “ Introduction into neuroglia”, Kyushu University, Fukuoka, January 2011, invited by Professor Mami Noda. 22. “ Physiology and pathophysiology of neuroglia”, MRC Centre for Neurodegeneration Research, Institute of Psychiatry, King's College London, December 2010, invited by Dr. Wendy Noble. A.Verkhratsky - Curriculum Vitae 16

23. “Ionotropic receptors in physiology and pathophysiology of astroglia”, Lecture at the Mini-symposium “Physiology and pathophysiology of astroglia”, University of Alabama at Birmingham, November 11, 2010, invited by Professor Vladimir Parpura. 24. “ATP as a neurotransmitter in the central nervous system”, June 2010, University of Konstanz, invited by Professor Helmut Plattner. 25. "ATP-mediated neurotransmission in neuronal-glial networks", May 2010, Facultad de Veterinaria Universidad Complutense de Madrid, invited by Professor Maria-Teresa Miras-Portugal. 26. "Physiology and pathophysiology of neuroglia", May 2010, Instituto Cajal, Madrid, invited by Professor Alfonso Araque 27. "Purinergic transmission in neural networks", March 2010, University of Split, invited by Professor Vladimir Parpura. 28. "Where the thoughts dwell: Physiology and pathophysiology of neuronal-glial networks", January 2010, University of Basque country, Bilbao, Invited by Professor Carlos Matute. 29. “Physiology and pathophysiology of glia”, December 2009, University of Louvain, Brussels, Invited by Dr. Philippe Gailly. 30. “ Physiology of neuronal-glial networking”, October 2009, Mediterranean Institute of Neurobiology, invited by Dr. Nail Burnashev. 31. “Purinergic transmission in the central nervous system”, July 2009, University of Tokyo, invited by Professor Masanobu Kano. 32. “Physiology of glia”, May 2009, University of Kazan (Russia), invited by Professor E. E. Nikolsky. 33. “ Purinergic signalling in neuronal-glial networks”, April 2009, University of Leipzig, invited by Professor Andreas Reichenbach. 34. “ Chemical transmission in neuronal-glial networks with special emphasis on glutamate and ATP”, December 2008, The University of Rochester, invited by Professor Maiken Nedergaard. 35. “ Purinergic transmission in neuronal-glial circuits”, September 2008, Max Delbruck Center of Molecular Medicine, Berlin, invited by Professor Helmut Kettenmann. 36. “ Excitatory purinergic transmission in the CNS”, August 2008, Neuroscience Centre, University of Helsinki, invited by Dr. Leonard Khiroug. 37. "Neurobiology of glia", June 2008, Jena University, Invited by Dr. Julian Grosskreutz. 38. "Physiology and pathophysiology of astroglia", May 2008, University Renes Descartes, Paris, invited by Prof. Jean-Marie Billard. 39. "Excitatory purinergic transmission in the CNS", May 2008, College de France, Paris, invited by Professor Christian Giaume. 40. "Neurobiology of Glia", July 2007, University of Novara, invited by Professor Carla Distasi. 41. "An outline of glial physiology", June 2007, Nencki Institute for Experimental Biology, Warsaw, invited by Prof. Leczek Kacmareck. 42. "Glutamate mediated neuronal-glial transmission", May 2007, Queens University, Belfast, invited by Prof. Alexander Zholos. A.Verkhratsky - Curriculum Vitae 17

43. "Physiology of Glia", May 2007, Neuroscience Centre, University of Helsinki, invited by Dr. Leonard Khiroug. 44. "Mechanisms of synaptic ATP release in the CNS", March 2007, University of Saarland, Homburg/Saar, invited by Prof. Veit Flockerzi. 45. "Vesicular release of ATP at central synapses", January 2007, Charite Department of Physiology, invited by Prof. Uwe Heinemann and Dr. Sergei Kirischuk. 46. "Glial neurobiology", November 2006, University Paris-5, Invited by Professor Alain Marty. 47. "Patching the glia: What we learned about brain “silent cells”; with a particular emphasis on Neuronal-glial transmission mediated through glutamate receptors", November 2006, Institute of Experimental Medicine, Prague, Invited by Professor Eva Sykova. 48. "Physiology of glia", July 2006, University of Leeds, invited by Professor Chris Peers. 49. "Molecular physiology of endoplasmic reticulum calcium signalling", June 2006, University of Lille, invited by Professor Natalia Prevarskaya. 50. "Integration in neuronal-glial circuits: Cellular and molecular mechanisms", June 2006, University of Valladolid, invited by Professor Javier Garcia-Sanchez. 51. “Mechanisms of neuronal-glial integration” February 2006, Oxford University, invited by Professor Anthony Galione. 52. “ Calcium signalling and neuronal functions”, February 2006, Carpathian University, Ivano- Frankovsk, invited by Professor Volodymir Luchshak. 53. “ Mechanisms of neuronal-glial interactions in the CNS”, January 2006, MRC Centre of Toxicology, Leicester, invited by Professor Pierluigi Nicotera. 54. “Endoplasmic reticulum and neuronal calcium signalling”, July 2005, University of Potsdam, invited by Professor Bernd Walz. 55. “ Neuronal-glial interactions: Role for chemical and electrical synapses”, May 2005, University of Kanazawa (Japan), invited by Professor Masanobu Kano. 56. “General physiology of glial cells” May 2005, University of Tokyo, invited by Professor K. Iino. 57. “Endoplasmic reticulum calcium signalling and neuronal function”, April 2005, INSERM, Montpellier, invited by Professor Patrice Mollard. 58. “ Endoplasmic reticulum and neuronal calcium signalling”, November 2004, University of Konstanz, invited by Professor Helmut Plattner. 59. "Endoplasmic reticulum calcium homeostasis", June 2004, University of Urbino, invited by Professor Andrea Minelli. 60. “ Endoplasmic reticulum calcium signalling and neuronal function”, June 2004, St. Boniface Hospital Research Centre, Winnipeg, The Samuel Weiner Distinguished Lecturer. 61. “ Neuronal-glial interactions - An overview”, June 2004, University of Manitoba, invited by Dr. P. Fernyhough. 62. "Endoplasmic reticulum, neuronal signalling and neurodegeneration", June 2004, University of Bilbao, invited by Professor Carlos Matute. A.Verkhratsky - Curriculum Vitae 18

63. "Endoplasmic reticulum calcium homeostasis and neuronal function", May 2004, University of Leicester, invited by Professor Pierluigi Nicotera. 64. "Endoplasmic reticulum calcium homeostasis", February 2004, University of Bordeaux, invited by Dr. F. Ichas. 65. "Calcium fluxes, endoplasmic reticulum and neuronal signalling", November 2003, Katolische Universitat Leuven, invited by Professor Bernd Nilius. 66. "Endoplasmic reticulum calcium signalling and neurodegeneration", March 2003, Max Plank Institute for Neuroscience Research, Cologne, Invited by Professor Wulf Paschen. 67. "Endoplasmic reticulum and neuronal signalling", February 2003, University of Oxford, invited by Professor Anant Parekh. 68. "Endoplasmic reticulum and neuronal signalling", September 2002, University of Leeds, Invited by Professor Chris Peers. 69. "Intra-ER Ca2+ dynamic: role for neuronal signalling" May 2002, University of Bristol, Invited by Professor Graham Collingridge. 70. "Endoplasmic reticulum as a signalling organelle” February 2002, University of Bonn, Invited by Professor Cristian Steinhauser. 71. "Neuronal CICR: Direct visualisation and properties", February 2002, Birmingham University, Invited by Dr. Emil Toescu. 72. "Direct visualisation of Ca2+-induced Ca2+ release in sensory neurones", November 2001, University of Padova, invited by Professor Tullio Pozzan. 73. "Intra-ER calcium dynamics in nerve cells", November 2001, SISSA Trieste, invited by Dr. Fabio Mammano. 74. "Neuronal calcium stores”, February 2001, Guy's University London, Invited by Dr. Arthur Butt. 75. "Glial calcium signalling", December 2000, University of Liverpool, invited by Professor R. Burgoyne. 76. "Ryanodine receptors, calcium stores and neuronal function", December 2000, Lundbeck AG/University of Copenhagen, invited by Dr. S. Larsen. 77. "Calcium signalling and information processing in glia", September 1999, University of Bordeaux, Invited by Dr. Francois Ichas. 78. "Glial membrane physiology", November 1998, University of Potsdam, Invited by Professor B. Walz. 79. "Local calcium signals in glial cells", November 1998, University of Bonn, Invited by Professor Christian Steinhäuser 80. "Calcium signalling in glia", June 1998, University of Kaiserslautern, Invited by Professor Joachim Deitmer 81. "Local calcium signals in Bergmann glial cells", June 1998, Homburg University, Homburg/Saar, Invited by Professor Arthur Konnerth 82. "Principles of calcium signalling", May 1998, University of Ankona, Invited by Professor Fiorenzo Conti. A.Verkhratsky - Curriculum Vitae 19

83. "Glial calcium", May 1998, San Rafaelle Institute, DIBIT, Milano, Invited by Professor Jacopo Meldolesi. 84. "Calcium homeostasis and signalling in glial cells in situ", September 1997, Max-Planck Institute for Biophysical Chemistry, Göttingen, invited by Professor Ervin Neher. 85. "Calcium signalling in glia", March 1997, University College London, invited by Dr. Frances Edwards. 86. “ Neurotransmitter receptors and calcium signalling in cerebellar Bergmann glial cells”, January 1997, Saarland University, invited by Professor Arthur Konnerth. 87. “ Calcium signals as a form of glial excitability”, January 1997, Max Planck Institute for Medical Research, Heidelberg, invited by Dr. Nail Burnashev. 88. "Calcium signalling in glial cells", June 1996, Heidelberg University, invited by Professor Veit Flokerzi. 89. “Calcium-induced calcium release in mammalian neurones and its modulation by cyclic ADP ribose”, St George School of Medicine, December 1994, invited by Professor Tom Bolton. 90. "Mechanisms of calcium homeostasis in central neurones", Oxford University, Department of Physiology, July 1993, invited by Dr. Frances Aschcroft. 91. "Caffeine-sensitive internal calcium stores in mammalian neurones", Royal Free Hospital, School of Medicine, University of London, July, 1993, invited by Professor Annette Dolphin. 92. "Age-dependent changes of calcium homeostasis in central mammalian neurones". Tropon Institute of Neurobiology, May 1993, invited by Professor B. Traber. 93. "Internal calcium stores in cerebellar, neocortical and hippocampal neurones", Max-Plank Institute of Medical Research, Heidelberg, January 1993, invited by Professor Bert Sakmann. 94. "Properties of internal calcium stores in central neurones", Liverpool University, October 1992, invited by Professor Ole Petersen. 95. "Changes of neuronal calcium currents within ageing" May 1992, Institute for General Physiology, Cologne University, invited by Professor Gerrit Isenberg.

2+ 2+ 96. "Age-dependent changes of [Ca ]i homeostasis including action of Ca -antagonists" Tropon Institute of Neurobiology, March 1992, invited by Professor B. Traber. 97. "Calcium currents and cytoplasmic calcium in aged sensory neurones", Max-Plank Institute of Medical Research, Heidelberg, February 1992, invited by Professor Bert Sakmann. 98. "Potassium channels in Schwann cells: Possible mechanisms for extracellular potassium homeostasis", May 1990, Technological University of Munich, invited by Professor Joseph Dudel. 99. "Rat cardiac slices: New tool for patch clamp experiments", April 1990, Institute for General Physiology, Cologne University, invited by Professor Gerrit Isenberg. 100. "Potassium currents in Schwann cells", Max-Plank Institute of Biophysical Chemistry, April 1990, invited by Dr. Walter Stühmer. 101. "Characteristics of single potassium channels in mouse Schwann cells", Max-Plank Institute of Medical Research, Heidelberg, December 1989, invited by Professor Bert Sakmann. A.Verkhratsky - Curriculum Vitae 20

LIST OF PUBLICATIONS (ISI Statistics: search for "Verkhratsky A*”: Total No. of citations, May 2014 >10500; H-index: 59 Cumulative impact factor: >1300)

Citations dynamics:

A. Books

1. V. Parpura & A. Verkhratsky, Eds. (2014): Pathological potential of neuroglia: Possible new targets for medical intervention. Springer-Verlag, pp. 646. 2. V. Parpura, A. Schousboe & A. Verkhratsky, Eds. (2014): Glutamate and ATP at interface of metabolism and signalling. Springer-Verlag, in press. 3. A. Verkhratsky & V. Parpura, Eds. (2014): Colloquium Series on Neuroglia in Biology and Medicine: From Physiology to Disease (E-textbook series); http://www.morganclaypool.com/page/neuroglia 4. A. Verkhratsky & A. Butt (2013): Physiology and Pathophysiology of Neuroglia, Wiley-Blackwell's, pp. 560. 5. G. Burnstock & A. Verkhratsky (2012) Purinergic Signalling in the Nervous System. Springer Verlag, pp. 715 6. A. Verkhratsky & O.H.Petersen, Eds. (2010): Calcium imaging in neurobiology. Humana Press/Springer Group, New York, Dordrecht, Heidelberg, London, pp. 254. 7. A. Verkhratsky & A. Butt (2007): Glial neurobiology. A textbook. Wiley & Sons, 1st Edition (Hardcover and paperback) pp. 224. 8. O.H. Petersen, C. Peers, P.F.T. Vaughan & A. Verkhratsky, Eds. (2000): Calcium as a Molecule for Cellular Integration. Proceedings of the International Symposium. pp. 86. A.Verkhratsky - Curriculum Vitae 21

9. A. Verkhratsky & E.C. Toescu, Eds. (1998): Integrative Aspects of Calcium Signalling. Plenum Press, pp. 408. 10. O.H. Petersen & A. Verkhratsky, Eds. (1998): Calcium Signalling in the Nervous System. Proceedings of the International Symposium. pp. 130. 11. P. Kostyuk & A. Verkhratsky (1995): Calcium Signalling in the Nervous System. Wiley & Sons, Chichester et al., pp. 220 12. V.I. Pidoplichko & A.N. Verkhratsky (1989): Electrophysiological Investigations of Isolated Cardiac Muscle Cells. Naukova Dumka, Kiev, pp. 270 (in Russian).

B. Edited special issues

13. A. Verkhratsky & V. Parpura, Eds. (2014): “Calcium channels”, European Journal of Pharmacology, v. 723, special issue, in press. 14. V. Parpura & A. Verkhratsky, Eds. (2012): “Neuroglia - more than a nervenkitt”, ASN Neuro, virtual (online) special collection, v. 4. 15. B. Fredholm & A. Verkhratsky, Eds. (2010): 80 years of purinergic signalling. Acta Physiologica (Oxford), special issue, v. 199, p. 91 - 241. 16. M. Nedergaard & A. Verkhratsky, Eds. (2010): Calcium in neurological diseases. Cell Calcium, special issue, v. 47, p. 101 - 198. 17. R. Borges, A. Nistri, E. Carbone & A. Verkhratsky, Eds. (2008): Physiology of chromaffin cells. Acta Physiologica (Oxford), special issue, v. 192, p. 143 - 335. 18. M.R. Duchen, A. Verkhratsky & S. Muallem, Eds. (2008): Mitochondria and calcium in health and disease, Cell Calcium, special issue, v. 44, p. 1 - 134. 19. P. Nicotera, G. Melino, O.H. Petersen & A. Verkhratsky, Eds. (2007): Cellular and molecular mechanisms of tissue damage and repair, Cell Death & Differentiation, special issue, v. 14, No. 7, p. 1235 - 1349. 20. R. M. Case, D. Eisner, A. Gourney, O.T. Jones, S. Muallem & A. Verkhratsky, Eds. (2007): Calcium channels and transporters. Cell Calcium, special issue, v. 42, No. 4/5, p. 345 - 520. 21. E.C. Toescu & A. Verkhratsky, Eds. (2007): Calcium hypothesis of ageing and neurodegeneration. Ageing Cell, special issue, v. 6, p. 265 - 370. 22. O.H. Petersen, O.A. Krishtal & A. Verkhratsky, Eds. (2006): Twenty-five years of the giga-seal patch-clamp. Pflügers Archiv European Journal of Physiology, special issue, v. 453, p. 233 - 420. 23. A. North & A. Verkhratsky, Eds. (2006): Purinergic transmission in the nervous system. Pflügers Archiv European Journal of Physiology, special issue, v. 452, p. 479 - 652. 24. H. Cheng & A. Verkhratsky, Eds. (2006): Calcium signalling in physiology and pathophysiology. Acta Pharmacologica Sinica, special issue, v. 27, No. 7, p. 767-958. 25. B. Nilius, K. Talavera & A. Verkhratsky, Eds. (2006): Molecular physiology of T-type calcium channels. Cell Calcium, special issue, v. 40, No. 2, p. 81 - 260. 26. O.H. Petersen, M. Michalak & A. Verkhratsky, Eds. (2005): Frontiers in calcium signalling. Cell Calcium, special issue, v. 38, No. 3/4, p. 161 - 446. 27. O.H. Petersen, A. Spat & A. Verkhratsky, Eds. (2005): Reactive Oxygen Species. Philosophical Transactions of the Royal Society: Biological Sciences, special issue, v. 360, No. 1464, p. 2197 - 2372. A.Verkhratsky - Curriculum Vitae 22

28. M. Mattson, A. Verkhratsky & E.C. Toescu, Eds. (2004): Ripe old age: Understanding normal aging. Trends in Neurosciences, special issue, v. 27, No. 10. 29. M. Mattson, A. Verkhratsky & E.C. Toescu, Eds. (2004): Synaptic function and behavior during normal ageing. Ageing Research Reviews, special issue, v. 3, No. 4. 30. M. Bootman, O.H. Petersen & A. Verkhratsky, Eds. (2002): Endoplasmic reticulum as a signalling organelle, Cell Calcium, special issue, v. 32, No 5/6. 31. A. Verkhratsky, O. Tibault & P. Landfield, Eds. (2002): Calcium signalling and neuronal pathology. European Journal of Pharmacology, special issue, v. 447, No 2/3. 32. A. Verkhratsky & O.H. Petersen, Eds. (1998): Calcium signalling in the nervous system, Cell Calcium special issue, v. 24, No. 5/6.

C. Papers

33. J. J. Rodríguez, C.Y. Yeh, S. Terzieva, M. Olabarria, M. Kulijewicz-Nawrot & A. Verkhratsky (2014): Complex and region specific changes in astroglial markers in the ageing brain. Neurobiology of Aging, v. 35, p. 15 - 23. 34. A. Verkhratsky, R.C. Reyes & V. Parpura (2013) TRP Channels Coordinate Ion Signalling in Astroglia. Reviews in Physiology, Biochemistry & Pharmacology, v. 166, p. 1 - 22. 35. J. J. Rodríguez H. N. Noristani & A. Verkhratsky (2014): Microglial response to Alzheimer’s pathology in the animal model is differentially modulated by physical exercise and environmental enrichment. Brain Structure & Function, E-pub ahead of print; doi: 10.1007/s00429-013-0693-5. 36. F. Zeidán-Chuliá, A. B. Salmina, N. A. Malinovskaya, M. Noda, A. Verkhratsky & J. C. Fonseca- Moreira (2014): The glial perspective of autism spectrum disorders. Neuroscience & Biobehavioral Reviews, v. 38, p. 160 - 172. 37. A. Verkhratsky & V. Parpura (2014): Store-operated calcium entry in neuroglia. Neuroscience Bulletin, v. 30, p. 125 - 133. 38. A. Verkhratsky & M. Nedergaard (2014): Astroglial cradle in the life of the synapse. Philosophical Transactions of the Royal Society Series B, in press. 39. M. K. Gottipati, A. Verkhratsky & V. Parpura (2014): Probing Astroglia with Carbon Nanotubes: Modulation of Form and Function. Philosophical Transactions of the Royal Society Series B, in press. 40. A. Faroni, R.J.P. Smith, P. Procacci, L.F. Castelnovo, A.J. Reid, V. Magnaghi & A. Verkhratsky

(2014): Purinergic signalling mediated by P2X7 receptors controls myelination in sciatic nerves Journal of Neuroscience Research, in press. 41. A. Verkhratsky & G. Burnstock (2014): Biology of Purinergic signalling: Its ancient evolutionary roots, its omnipresence and its multiple functional significance. BioEssays, in press. 42. F. Zeidán-Chuliá, B.-H. Neves de Oliveira, A. B. Salmina, M. F. Casanova, D. Pens Gelain, M. Noda, A. Verkhratsky & J. C. Fonseca Moreira (2014): Altered expression of Alzheimer´s disease- related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy. Cell Death & Disease, v. 5, p. e1250n. 43. A. Zayas-Santiago, S. Agte, Y Rivera, J. Benedikt, E. Ulbricht, A. Karl, J. Davila, A. Savvinov, Y. Kucheryavikh, Mikhail Inyushin, L. Cubano, T. Pannike, R. W. Veh, M. Francke, A. Verkhratsky, M. J. Eaton, A. Reichenbach & S. N. Skatchkov (2014): Unidirectional Photoreceptor-to-Müller Glia Coupling and Unique K+ Channel Expression in Caiman Retina. PLOS One, v. 9, e97155. A.Verkhratsky - Curriculum Vitae 23

44. A. Verkhratsky, J. J. Rodríguez &V. Parpura (2014): Neuroglia in ageing and disease, Cell & Tissue Research, e-pub ahead of print; doi 10.1007/s00441-014-1814-z. 45. R. F Stout, A. Verkhratsky & V. Parpura (2014): Caenorhabditis elegans glia modulate neuronal activity and behavior. Frontiers in Cellular Neuroscience, v. 8, a67. 46. S.W. Rothwell, P.J. Stansfeld, L. Bragg, A. Verkhratsky & R.A. North (2014): Direct gating of ATP-

activated ion channels (P2X2 Receptors) by lipophilic attachment at the outer end of the second transmembrane domain. The Journal of Biological Chemistry, v. 289, p. 618-626. 47. V. Ronco, A. A. Grolla, T. N. Glasnov, P. L. Canonico, A. Verkhratsky, A. A. Genazzani & D. Lim (2014): Differential deregulation of astrocytic calcium signalling by amyloid-β, TNFα, IL-1β and LPS. Cell Calcium, v. 55, p. 219 - 229 48. A. Verkhratsky & V. Parpura (2014): Neurological and psychiatric disorders as a neuroglial failure. Periodicum Biologorum, in press. 49. D. Lim, V. Ronco, A. A. Grolla, A. Verkhratsky* & A. A. Genazzani* (2014): Glial calcium signalling in Alzheimer’s disease Reviews in Physiology, Biochemistry & Pharmacology, in press (*corresponding authors). 50. H. Kettenmann, F. Kirchhoff & A. Verkhratsky (2013): Microglia: New roles for the synaptic stripper, Neuron, v. 77, p. 10 - 18. 51. A. Faroni, S. W. Rothwell, A. A. Grolla, G. Terenghi, V. Magnaghi & A. Verkhratsky (2013): Differentiation of adipose-derived stem cells into Schwann cell phenotype induces expression of P2X receptors that control cell death. Cell Death & Disease, v. 4, p. e743 52. C. F. Rose, A. Verkhratsky & V. Parpura (2013): Astrocyte glutamine synthetase: pivotal in health and disease. Biochemical Society Transactions, v. 41, p. 1518 - 1524. 53. C.Y. Yeh, A. Verkhratsky, S. Terzieva & J.J. Rodriguez (2013): Glutamine synthetase in astrocytes from entorhinal cortex of the triple transgenic animal model of Alzheimer's disease is not affected by pathological progression. Biogerontology, v. 14, p. 777 - 787. 54. M.A. Fiol-deRoque, R. Gutierrez-Lanza, M. Torres, S. Terés, P. Barceló, R.V. Rial, A. Verkhratsky, P.V. Escribá, X. Busquets, & J.J. Rodríguez (2013): Cognitive recovery and restoration of cell proliferation in the dentate gyrus in the 5XFAD transgenic mice model of Alzheimer's disease following 2-hydroxy-DHA treatment. Biogerontology, v. 14, p. 763 - 775. 55. A. Grigorov, A. Moskalyuk, M. Kravchenko, N. Veselovsky, A. Verkhratsky & S. Fedulova (2013):

Kv7 potassium channel subunits and M-currents in cultured hippocampal interneurons. Pflügers Archiv - European Journal of Physiology, E-pub ahead of print, doi: 10.1007/s00424-013-1406-x. 56. A. Verkhratsky & V. Parpura (2013): Calcium signalling and calcium channels: Evolution and general principles. European Journal of Pharmacology, E-pub ahead of print, doi: 10.1016/j.ejphar.2013.11.013. 57. A. Verkhratsky, J. J. Rodríguez & L. Steardo (2013): Astrogliopathology: a central element of neuropsychiatric diseases? The Neuroscientist, e-pub ahead of print, doi: 10.1177/1073858413510208. 58. M. Kulijewicz-Nawrot, E. Syková, A. Chvátal, A. Verkhratsky* and J. J. Rodríguez* (2013): Astrocytes and glutamate homeostasis in Alzheimer’s disease: a decrease in glutamine synthetase but not in glutamate transporter-1 in the prefrontal cortex. ASN Neuro, v. 5, e00123, (*corresponding author). 59. R.C. Reyes, A. Verkhratsky & V. Parpura (2013) TRPC1-mediated Ca and Na signalling in astroglia: Differential filtering of extracellular cations. Cell Calcium, v. 54, p. 120 - 125. 60. J.J. Rodriguez, H.N. Noristani, T. Hilditch, M. Olabarria, C.Y. Yeh, J. Witton & A. Verkhratsky (2013) Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease. Neuroscience Letters, v. 552, p. 129 - 134. A.Verkhratsky - Curriculum Vitae 24

61. J.J. Rodriguez, S. Terzieva, M. Olabarria, R.G. Lanza & A. Verkhratsky (2013) Enriched environment and physical activity reverse astrogliodegeneration in the hippocampus of AD transgenic mice. Cell Death & Disease v. 4, e678 62. E. Alberdi, A. Wyssenbach, M. Alberdi, M. V. Sanchez-Gomez, F. Cavaliere, J. J. Rodriguez, A. Verkhratsky, & C. Matute (2013): Ca2+-dependent endoplasmic reticulum stress correlates with astrogliosis in oligomeric amyloid -treated astrocytes and in a model of Alzheimer's Disease." Aging Cell, v. 12, p. 292 - 302. 63. O. Forostyak, N. Romanyuk, A. Verkhratsky, E. Sykova, and G. Dayanithi (2013): Plasticity of Calcium Signaling Cascades in Human Embryonic Stem Cell-Derived Neural Precursors. Stem Cells and Development, v. 22, p. 1506 - 1521. 64. A. A. Grolla, J. A. Sim, D. Lim, J. J. Rodriguez, A. A. Genazzani & A. Verkhratsky (2013): Amyloid-  and Alzheimer´s disease type pathology differentially affects calcium signalling toolkit in astrocytes from different brain regions. Cell Death & Disease, v. 4, e623 65. H. Plattner & A. Verkhratsky (2013): Calcium signalling early in evolution – all but primitive: 2+ InsP3- and ryanodine-receptor-type Ca -release channels in lower eukaryotes. Journal of Cell Science, v. 126, p. 2141 - 2150. 66. A. Verkhratsky, J. J. Rodríguez & V. Parpura (2013): Astroglia in neurological diseases. Future Neurology, v. 8, p. 149 - 158. 67. V. Parpura & A. Verkhratsky (2013): Astroglial amino acid-based transmitter receptors. Amino Acids, v. 44, 1151 - 1158. 68. V. Parpura & A. Verkhratsky (2013): Astrogliopathology: Could nanotechnology restore aberrant calcium signalling and pathological astroglial remodelling? Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, v. 1833, p. 1625 - 1631. 69. A. Verkhratsky, M. Noda, V. Parpura & S. Kirischuk (2013) Sodium fluxes and astroglial function. Advances in Experimental Medicine and Biology, v. 961, p. 295 - 305. 70. M. Noda, M. Ifuku, Y. Mori & A. Verkhratsky (2013): Calcium influx through reversed NCX controls migration of microglia. Advances in Experimental Medicine and Biology, v. 961, p. 289 - 294. 71. I. Shibuya, T. Moriya, T. Kayano, N. Kitamura, Y. Z. Hosaka, A. Asano, O. Forostyak, A. Verkhratsky, C. Viero, G. Dayanithi & E. C. Toescu (2012): Vasopressin-induced intracellular Ca 2+ concentration responses in non-neuronal cells of the rat dorsal root ganglion. Brain Research, v. 1483, p. 1 - 12. 72. S. Kirischuk, V. Parpura & A. Verkhratsky (2012): Sodium dynamics: another key to astroglial excitability? Trends in Neurosciences, v. 35, p. 497 - 506. 73. V. Parpura & A. Verkhratsky (2012): Homeostatic function of astrocytes: Ca2+ and Na+ signalling. Translational Neuroscience, v. 3, p. 334 - 344. 74. V. Parpura & A. Verkhratsky (2012): Astrocytes revisited: Concise historic outlook on glutamate homeostasis and signalling. Croatian Medical Journal, v. 15, p. 518 - 528. 75. V. Compan, A. Baroja-Mazo, L. Bragg, A. Verkhratsky, J. Perroy & P. Pelegrin (2012): A genetically encoded IL-1β BRET sensor to monitor inflammasome activity. Journal of Immunology, v. 189, p. 2131 - 2137. 76. J.J. Rodriguez, H.N. Noristani & A. Verkhratsky (2012): The serotonergic system in ageing and Alzheimer's disease. Progress in Neurobiology, v. 99, p. 15 - 41. 77. M. Kulijewicz-Nawrot, A. Verkhratsky, A. Chvatal, E.Sykova & J.J. Rodriguez (2012): Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer's disease. Journal of Anatomy, v. 221, p. 252 - 262. A.Verkhratsky - Curriculum Vitae 25

78. H.N. Noristani, A. Verkhratsky* & J.J. Rodriguez* (2012) High tryptophan diet reduces CA1 intraneuronal beta-amyloid in the triple transgenic mouse model of Alzheimer's disease. Aging Cell, v. 11, p. 810 - 822 (*corresponding authors). 79. M. Nedergaard & A. Verkhratsky (2012): Artifact versus reality - How astrocytes contribute to synaptic events? Glia, v. 60, p. 1013 - 1023. 80. A. Verkhratsky, J.J. Rodriguez & V. Parpura (2012): Neurotransmitters and integration in neuronal-astroglial networks. Neurochemical Research, v. 37, p. 2326 - 2338 81. H. Franke, A. Verkhratsky, G. Burnstock & P. Illes (2012): Pathophysiology of astroglial purinergic signalling. Purinergic Signalling, v. 8, p. 629 - 657. 82. A. Verkhratsky, M. V. Sofroniew, A. Messing, N. C. deLanerolle, D. Rempe, J. J. Rodríguez & M. Nedergaard (2012): Neurological diseases as primary gliopathies: a reassessment of neurocentrism. ASN Neuro, v. 4, e00082. 83. R. Zorec, A. Araque, G. Carmignoto, P. G. Haydon, A. Verkhratsky & V. Parpura (2012): Astroglial excitability and gliotransmission: An appraisal of Ca2+ as a signaling route. ASN Neuro, v. 4, e00080. 84. R.C. Reyes, A. Verkhratsky & V. Parpura (2012): Plasmalemmal Na+/ Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes. ASN Neuro, v. 4, e00075. 85. W. Ma, V. Compan, W. Zheng, E. Martin, R. A. North, A. Verkhratsky* & A. Surprenant (2012): Pannexin 1 forms an anion-selective channel. Pflügers Archiv European Journal of Physiology, v. 463, p. 585-592 (*corresponding author). 86. V. Parpura, M.T. Heneka, V. Montana, S.H. Oliet, A. Schousboe, P.G. Haydon, R.F. Stout Jr., D.C. Spray, A. Reichenbach, T. Pannicke, M. Pekny, M. Pekna, R. Zorec & A. Verkhratsky (2012): Glial cells in (patho)physiology. Journal of Neurochemistry, v. 121, p. 4 - 27. 87. G. Dayanithi, O. Forostyak, Y. Ueta, A. Verkhratsky & E.C. Toescu (2012): Segregation of calcium signalling mechanisms in magnocellular neurones and terminals. Cell Calcium v. 51, p. 293-299. 88. E.M. Knight, A. Verkhratsky, S.M. Luckman, S.M. Allan & C.B. Lawrence (2012): Hypermetabolism in a triple-transgenic mouse model of Alzheimer's disease. Neurobiology of Aging, v. 33, p. 187 - 193. 89. G. Burnstock & A. Verkhratsky (2012): Purinergic signaling. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, v. 1, p. 116 - 125. 90. G. Burnstock & A. Verkhratsky (2012): Evolution of P2X receptors. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, v. 1, p. 188 - 200. 91. A. Verkhratsky, Y. Pankratov, U. Lalo & M. Nedergaard (2012): P2X receptors in neuroglia. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, v. 1, p. 151 - 161. 92. U. Lalo, A. Verkhratsky, G. Burnstock & Y. Pankratov (2012): P2X receptor-mediated synaptic transmission. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, v. 1, p. 297–309. 93. E. Zherebitskaya , J. Schapansky, E. Akude, D. R. Smith, R. Van der Ploeg, N. Solovyova, A. Verkhratsky & P. Fernyhough (2012): Sensory neurons derived from diabetic rats have diminished internal Ca2+ stores linked to impaired reuptake by the endoplasmic reticulum. ASN Neuro, v. 4, e00072. 94. C.Y. Yeh, B. Vadhwana, A. Verkhratsky & J.J. Rodriguez-Arellano (2012): Early astrocytic atrophy in the entorhinal cortex of a triple transgenic animal model of Alzheimer's disease. ASN Neuro, v. 3, e00071. 95. V. Parpura & A. Verkhratsky (2012): The astrocyte excitability brief: From receptors to gliotransmission. Neurochemistry International, v. 61, p. 610 - 621. A.Verkhratsky - Curriculum Vitae 26

96. A. Verkhratsky, J.J. Rodríguez & V. Parpura (2012): Calcium signalling in astroglia. Molecular & Cellular Endocrinology, v. 353, p. 45 - 56. 97. P. Illes, A. Verkhratsky, G. Burnstock & H. Franke (2012): Astroglial P2X receptors in the central and peripheral nervous system. Neuroscientist, v. 18, p. 422 - 438. 98. H. N. Noristani, R. S. Meadows, M. Olabarria, C. Y. Yeh, A. Verkhratsky & J.J. Rodríguez (2011): Increased serotonin terminal density in CA1 of the hippocampus in a triple transgenic mouse model of Alzheimer’s disease: an ultrastructural study. Cell Death & Disease, v. 2, e210. 99. H. Kettenmann & A. Verkhratsky (2011): Neuroglia, der lebende Nervenkitt. Fortschritte der Neurologie – Psychiatrie, v. 79, p. 588 - 597. 100. J. J. Rodríguez, M. Olabarria, H. N. Noristani, C.-Y. Yeh & A. Verkhratsky (2011): Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimer's disease. Current Alzheimer Research, v. 8, p. 707 - 717. 101. M. Olabarria, H.N. Noristani, A. Verkhratsky & J.J. Rodriguez (2011): Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: Mechanism for deficient glutamatergic transmission? Molecular Neurodegeneration, v. 6, 55. 102. U. Lalo, O. Palygin, R.A. North, A. Verkhratsky* & Y. Pankratov (2011): Age-dependent remodelling of ionotropic signalling in cortical astroglia. Aging Cell, v. 10, p. 392 - 402, (*corresponding author). 103. H. Kettenmann*, U.-K. Hanisch, M. Noda & A. Verkhratsky* (2011): Physiology of microglia. Physiological Reviews, v. 91, p. 461 - 553, (*corresponding authors). 104. U. Lalo, A. Verkhratsky, & Y. Pankratov (2011): Ionotropic ATP receptors in neuronal-glial communication. Seminars in Cell & Developmental Biology, v. 22, p. 220 - 228. 105. J. J. Rodriguez & A. Verkhratsky (2011): Neuroglial roots of neurodegenerative diseases? Molecular Neurobiology, v. 43, p. 87 - 96. 106. J. J. Rodríguez & A. Verkhratsky (2011): Neurogenesis in Alzheimer’s disease. Journal of Anatomy (Oxford), v. 219, p. 78 - 89. 107. U. Lalo, Y. Pankratov, V. Parpura & A. Verkhratsky (2011): Ionotropic receptors in neuronal- astroglial signalling: What is the role of “excitable” molecules in non-excitable cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, v. 1813, p. 992 - 1002. 108. V. Parpura, V. Grubisic & A. Verkhratsky (2011): Ca2+ sources for the exocytotic release of glutamate from astrocytes. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, v. 1813, p. 984 - 991. 109. O. Kopach, I. Kruglikov, T. Pivneva, N. Voitenko, A. Verkhratsky & N. Fedirko (2011): Mitochondria adjust Ca2+ signaling regime to a pattern of stimulation in salivary acinar cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, v. 1813, p. 1740 - 1748. 110. G. Burnstock, B.B. Fredholm & A. Verkhratsky (2011): Adenosine and ATP receptors in the brain. Current Topics in Medicinal Chemistry, v. 11, 973 - 1011. 111. A. Verkhratsky, V. Parpura & J. J. Rodriguez (2011): Where the thoughts dwell: The physiology of neuronal-glial "diffuse neural net". Brain Research Reviews, v. 66, p. 133 - 151. 112. Y. Komori, M. Tanaka, M. Kuba, M. Ishii, M. Abe, N. Kitamura, A. Verkhratsky, I. Shibuya & G. Dayanithi (2010): Ca2+ homeostasis, Ca2+ signalling and somatodendritic vasopressin release in adult rat supraoptic nucleus neurones, Cell Calcium, v. 48, p. 324 - 332. * 113. O. Palygin, U. Lalo, A. Verkhratsky & Y. Pankratov (2010): Ionotropic NMDA and P2X1/5 receptors mediate synaptically induced Ca2+-signalling in cortical astrocytes. Cell Calcium, v. 48, 225 - 231. A.Verkhratsky - Curriculum Vitae 27

114. A. Verkhratsky & V. Parpura (2010): Recent advances in (patho)physiology of astroglia. Acta Pharmacologica Sinica, v. 31, p. 1044 - 1054. 115. A. Guerrero-Hernandez, A. Dagnino-Acosta & A. Verkhratsky (2010): An intelligent sarco- endoplasmic reticulum Ca2+ store: Release and leak channels have differential access to a concealed Ca2+ pool, Cell Calcium, v. 48, 143 - 149. 116. G. Burnstock, B.B. Fredholm, R.A. North, & A. Verkhratsky (2010): The birth and postnatal development of purinergic signalling. Acta Physiologica (Oxford), v. 199, p. 93 - 147. 117. C. Viero, I. Shibuya, N. Kitamura, A. Verkhratsky, H.Fujihara, A. Katoh, Y. Ueta, H. H. Zingg, A. Chvatal, E. Sykova & G. Dayanithi (2010): Oxytocin: crossing the bridge between basic science and pharmacotherapy. CNS Neuroscience & Therapeutics, v. 16, p. e138 - e156. 118. A. Verkhratsky (2010): Physiology of neuronal-glial networking. Neurochemistry International, v. 57, p. 332 - 343. 119. N. Solovyova & A. Verkhratsky (2010): Measurement of free Ca2+ concentration in the lumen of neuronal endoplasmic reticulum. Cold Spring Harbor Protocols, 2010: doi:10.1101/pdb.prot4783. 120. H. N. Noristani, M. Olabarria, A. Verkhratsky & J. J. Rodríguez (2010): Serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in CA1 are of hippocampus in a triple transgenic mouse model of Alzheimer’s Disease. European Journal of Neuroscience, v. 32, p. 71 - 79. 121. A. Verkhratsky, M. Olabarria, H. N. Noristani, C.-Y. Yeh & J. J. Rodriguez (2010): Astrocytes in Alzheimer's disease, Neurotherapeutics, v. 7, p. 399 - 412. 122. V. I. Teslenko, E. G. Petrov, A. Verkhratsky & O. A. Krishtal (2010): Novel mechanism for temperature-independent transitions in flexible molecules: Role of thermodynamic fluctuations. Physical Review Letters, v. 104, e178105. 123. J. J. Rodríguez, J. Witton, M. Olabarria, H.N. Noristani & A. Verkhratsky (2010): Increase in the density of resting microglia precedes neuritic plaques formation and microglial activation in a transgenic model of Alzheimer’s disease. Cell Death & Disease, v. 1, e1. 124. M. Olabarria, H. N. Noristani, A. Verkhratsky* & J. J. Rodríguez (2010) Concomitant astroglia atrophy and astrogliosis in a triple transgenic animal model of Alzheimer disease, Glia, v. 58, p. 831 - 838 (*corresponding author). 125. G. Burnstock & A. Verkhratsky (2010): Vas deferens – a model used to establish sympathetic cotransmission. Trends in Pharmacological Sciences, v. 31, p. 131 - 139. 126. G. Burnstock & A. Verkhratsky (2010): Long term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death. Cell Death & Disease, v. 1, e9. 127. M. Nedergaard, J. J. Rodríguez & A. Verkhratsky (2010): Glial calcium and diseases of the nervous system. Cell Calcium, v. 47, p. 140 - 149. 128. M. Heneka, J. J. Rodríguez & A. Verkhratsky (2010): Neuroglia in neurodegeneration. Brain Research Reviews, v. 63, p. 189 - 211. 129. M. V. Mamenko, I. V. Chizhmakov, T. M. Volkova, A. Verkhratsky & O.A. Krishtal (2010):

Extracellular cAMP inhibits P2X3 receptors in rat sensory neurones though G-protein mediated mechanism. Acta Physiologica (Oxf), v. 199, p. 199 - 204. 130. G. Burnstock & A. Verkhratsky (2009): Evolutionary origins of purinergic signalling system. Acta Physiologica (Oxford), v. 195, p. 415 - 447. 131. J.J. Rodriguez, V. Jones & A. Verkhratsky (2009): Impaired cell proliferation in the subventricular zone in an Alzheimer disease model. Neuroreport, v. 20, p. 907 - 912. 132. V. Jones, J.J. Rodriguez, A. Verkhratsky & O.T. Jones (2009): A lentivirally-delivered photoactivatable GFP to assess continuity in the endoplasmic reticulum of neurones and glia. Pflügers Archiv European Journal of Physiology, v. 458, p. 809 - 818. A.Verkhratsky - Curriculum Vitae 28

133. A. Verkhratsky, O.A. Krishtal & G. Burnstock (2009): Purinoceptors on neuroglia. Molecular Neurobiology, v. 39, p. 190-208. 134. M. P. Abbracchio, G. Burnstock, A. Verkhratsky & H. Zimmermann (2009): Purinergic signalling in the nervous system: an overview. Trends in Neuroscience, v. 32, p. 19 - 29. 135. J. J. Rodríguez, M. Olabarria, A. Chvatal & A. Verkhratsky (2009): Astroglia in dementia and Alzheimer’s disease. Cell Death & Differentiation, v. 16, p. 378 - 385. 136. A. Verkhratsky (2009): Neuronismo y reticulismo: Neuronal-glial circuits unify the reticular and neuronal theories of brain organisation. Acta Physiologica (Oxford), v. 195, p. 111 - 122. 137. A. Verkhratsky, M. Anděrová & A. Chvátal (2009): Differential calcium signalling in neuronal-glial networks. Frontiers in BioSciences, v. 14, p. 2004 - 2016. 138. Y. Pankratov, U. Lalo, O. A. Krishtal & A. Verkhratsky (2009): P2X receptors and synaptic plasticity, Neuroscience, v. 158, p. 137 - 148. 139. H. Kettenmann & A. Verkhratsky (2008): Neuroglia: 150 years after. Trends in Neuroscience, v. 31, p. 653 - 659. 140. U. Lalo Y. Pankratov, S. P. Wichert, M. J. Rossner, R. A. North, F. Kirchhoff & A. Verkhratsky

(2008): P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes. Journal of Neuroscience, v. 28, p. 5473 - 5480. 141. J.J. Rodríguez, V.C. Jones, M. Tabuchi, S.M. Allan, E.M. Knight, F.M. LaFerla, S. Oddo & A. Verkhratsky (2008): Impaired adult neurogenesis in the dentate gyrus of a triple transgenic mouse model of Alzheimer's disease. PLOS One, v. 3, e2935.

142. V. Khmyz, O. Maximyuk, V. Teslenko, A. Verkhratsky & O. A. Krishtal (2008): P2X3 receptor gating near normal body temperature. Pflügers Archiv European Journal of Physiology, v. 456, p. 339- 347. 143. N. Hamilton, S. Vayro, F. Kirchhoff, A. Verkhratsky, J. Robbins, D. Gorecki & A. M. Butt (2008): Mechanisms of ATP- and glutamate-mediated calcium signaling in white matter astrocytes. Glia, v. 56, p. 734 - 749. 144. A. Chvatal, M. Anderova, H. Neprasova, I. Prajerova, J. Benesova, O. Butenko & A. Verkhratsky (2008): Pathological potential of astroglia. Physiol Res. v. 57, Suppl. 3, p. S101 - S110. 145. V. C. Jones, L. McKeown, A. Verkhratsky and O. T. Jones (2008): LV-pIN-KDEL: a novel lentiviral vector for probing the dynamics and morphology of the endoplasmic reticulum in live neurones. BMC Neuroscience v. 9:10. 146. R. Borges, E. Carbone, A. Nistri & A. Verkhratsky (2008): Chromaffin cells at the beginning of 21st century. Acta Physiologica (Oxford), v. 192, p. 143 - 144. 147. J. García-Sancho & A. Verkhratsky (2008): Cytoplasmic organelles determine complexity and specificity of calcium signalling in adrenal chromaffin cells. Acta Physiologica (Oxford), v. 192, p. 263 - 271. 148. M. R. Duchen, A. Verkhratsky & S. Muallem (2008): Mitochondria and calcium in health and disease. Cell Calcuim, v. 44, p. 1 - 5. 149. A. Verkhratsky & P. Fernyhough (2008): Mitochondrial malfunction and Ca2+ dyshomeostasis drive neuronal pathology in diabetes. Cell Calcium, v. 44, p. 112 - 122. 150. J. J. Rodrugues, H. A. Davies, M. L. Errington, A. Verkhratsky, T. V .P. Bliss & M. G. Stewart (2008): Expression of Arg3.1/Arc in hippocampal dentate gyrus astrocytes: Ultrastructural evidence and co-localization with glial fibrillary acidic protein. Journal of Cellular and Molecular Medicine, v. 12, p. 671 - 678. 151. S. Kirischuk, H. Kettenmann & A. Verkhratsky (2007): Membrane currents and cytoplasmic sodium transients generated by glutamate transport in Bergmann glial cells. Pflügers Archiv European Journal of Physiology v. 454, p. 245 - 252. A.Verkhratsky - Curriculum Vitae 29

152. A. R. Cole, W. Noble, L.V. Aalten, F. Plattner, R. Meimaridou, D. Hogan, M. Taylor, J. Lafrancois, F. Gunn-Moore, A. Verkhratsky, S. Oddo, F. Laferla, K. P. Giese, K. T. Dineley, K. Duff, J. C. Richardson, S. D. Yan, D. P. Hanger, S. M. Allan, C. Sutherland (2007): Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression. Journal of Neurochemistry, v. 103, p.1132 - 1144. 153. R. H. Williams, T. Jensen, A. Verkhratsky, L. Fugger, D. Burdakov (2007): Orexin cell firing

encodes physiological levels of acid and CO2 homeostatic control of hypothalamic behavioral orchestrators. Proceedings of National Academy of Sciences USA, v. 104, p. 10685 - 10690. 154. U. Lalo, A. Verkhratsky & Y. Pankratov (2007): Ivermectin potentiates ATP-induced ion currents

in cortical neurones: evidence for functional expression of P2X4 receptors? Neuroscience Letters, v. 421, p. 158-162. 155. P. Nicotera, O. H. Petersen, G. Melino & A. Verkhratsky (2007): Janus a God with two faces: Death and survival utilise same mechanisms conserved by evolution. Cell Death & Differentiation, v. 14, p. 1235 - 1236. 156. C. Giaume, F. Kirchhoff, C. Matute, A. Reichenbach & A. Verkhratsky (2007): Glia: The fulcrum of brain diseases. Cell Death & Differentiation, v. 14, p. 1324 - 1335. 157. R. M. Case, D. Eisner, A. Gourney, O. T. Jones, S. Muallem & A. Verkhratsky (2007): Evolution of calcium homeostasis: from birth of the first cell to an omnipresent signalling system. Cell Calcium, v. 42, p. 345 - 350. 158. O. H. Petersen & A. Verkhratsky (2007): Endoplasmic reticulum calcium tunnels integrate signalling in polarised cells. Cell Calcium, v. 42, p. 373 - 378. 159. E. C. Toescu & A. Verkhratsky (2007): The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal ageing. Ageing Cell, v. 6, p. 267 - 273. 160. Y. Pankratov, U. Lalo, A. Verkhratsky & R.A. North (2007): Quantal release of ATP in mouse cortex. Journal of General Physiology, v. 129, p. 257 - 265. 161. A. Verkhratsky & F. Kirchhoff (2007): NMDA receptors in glia. Neuroscientist, v. 13, p. 28 - 37. 162. A. Verkhratsky & F. Kirchhoff (2007): Glutamate-mediated neuronal-glial transmission. Journal of Anatomy, v. 210, p. 651 - 660. 163. U. Lalo, Y. Pankratov, R.A. North & A. Verkhratsky (2007): Spontaneous autocrine release of protons activates ASIC-mediated currents in HEK293 cells. Journal of Cellular Physiology, v. 212, p. 473 - 480. 164. G. Arboleda, T. J. Huang, C. Waters, A. Verkhratsky, P. Fernyhough & R. M. Gibson (2007): Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase–Akt pathway is inhibited by C2-ceramide in CAD cells. European Journal of Neuroscience, v. 25, p. 3030 - 3038. 165. P. M. D. Watson, M. J. Humphries, J. Relton, N. J. Rothwell, A. Verkhratsky & R. M. Gibson (2007): Integrin-binding RGD peptides induce rapid intracellular calcium increases and MAPK signaling in cortical neurons. Molecular & Cellular Neuroscience, v. 34, p. 147 - 154. 166. D. Burdakov, L. Fugger, L. T. Jensen, R. Williams, H. Alexopoulos, I. Fearon, I. O'Kelly, O. Gerasimenko & A. Verkhratsky (2006): Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose. Neuron, v. 50, p. 711 - 722. 167. U. Lalo, Y. Pankratov, F. Kirchhoff, A. North & A. Verkhratsky (2006): NMDA receptors mediate neuron to glia signalling in mouse cortical astrocytes. Journal of Neuroscience, v.26, p. 2673 - 2683. 168. Y. Pankratov, U. Lalo, A. Verkhratsky & A. North (2006) Vesicular release of ATP at central synapses. Pflügers Archiv European Journal of Physiology, v. 452, p. 589 - 597. A.Verkhratsky - Curriculum Vitae 30

169. D. Burdakov & A. Verkhratsky (2006): Biophysical re-equilibration of Ca2+ fluxes as a simple biologically plausible explanation for complex intracellular Ca2+ release patterns. FEBS Letters, v. 380, p. 463 - 468. 170. P. Pakhotin, A. J. Harmar, A. Verkhratsky & H. Piggins (2006): VIP receptors control excitability of suprachiasmatic nuclei neurones. Pflügers Archiv European Journal of Physiology, v. 452, 7-15. 171. N. Ismailova, A. Verkhratsky & M. Dascombe (2006): Changes in mGlu5 receptor expression in the basal ganglia of reserpinised rats. European Journal of Pharmacology, v. 545, p.134-141. 172. A. Verkhratsky, O. Krishtal & O.H. Petersen (2006): From Galvani to patch-clamp: Development of electrophysiology. Pflügers Archiv European Journal of Physiology, v. 453, p. 233 - 247. 173. A. Verkhratsky (2006): Patching the glia reveals the functional organisation of the brain. Pflügers Archiv European Journal of Physiology, v. 453, p. 411 - 420. 174. R. A. North & A. Verkhratsky (2006): Purinergic transmission in the central nervous system. Pflügers Archiv European Journal of Physiology, v. 452, p. 479 - 485. 175. A. Verkhratsky (2006): Calcium ions and integration in neural circuits. Acta Physiologica, v. 187, p. 357 - 369. 176. A. Verkhratsky & E. C. Toescu (2006): Neuronal-glial circuits as a substrate for CNS integration. Journal of Cellular and Molecular Medicine, v. 10, p. 826-836. 177. B. Nilius, K. Talavera & A. Verkhratsky (2006): T-type calcium channels: The NEVER ENDING story. Cell Calcium, v. 40, p. 81-88. 178. H. Cheng, S. Wei, L. Wei & A. Verkhratsky (2006): Calcium signalling in physiology and pathophysiology. Acta Pharmacologica Sinica, v. 27, p. 767 - 772. 179. A. Verkhratsky (2006): Glial calcium signalling in physiology and pathophysioloigy. Acta Pharmacologica Sinica, v. 27, p. 773 - 780. 180. D. Burdakov, O. Gerasimenko & A. Verkhratsky (2005): Physiological changes in glucose differentially modulate the excitability of hypothalamic MCH and orexin neurons in situ. Journal of Neuroscience, v. 25, p. 2429 - 2433. 181. T.-J. Huang, N. M. Sayers, A. Verkhratsky & P. Fernyhough (2005): Neurotrophin-3 prevents mitochondrial dysfunction in sensory neurons of streptozotocin-diabetic rats. Experimental Neurology, v. 194, p.279-283. 182. P. Pakhotin & A. Verkhratsky (2005): Electrical synapses between Bergmann glial cells and Purkinje neurones in rat cerebellar slices. Molecular & Cellular Neuroscience, v. 28, p. 79 - 84. 183. T.-Z. Huang, A. Verkhratsky & P. Fernyhough (2005): Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons. Molecular & Cellular Neuroscience, v. 28, p. 42 - 54. 184. A. Verkhratsky (2005): Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons. Physiological Reviews, v. 85, p. 201 - 279. 185. O.H. Petersen, A Spät & A. Verkhratsky (2005): Introduction: reactive oxygen species in health and disease. Philosophical Transactions of the Royal Society: Biological Sciences, special issue, v. 360, p. 2197 - 2199. 186. D. Burdakov, S. Luckman & A. Verkhratsky (2005): Molecular physiology of glucose-sensing mechanisms in the CNS. Philosophical Transactions of the Royal Society: Biological Sciences, special issue, v. 360, p. 2227 - 2235. 187. O.H. Petersen, M. Michalak & A. Verkhratsky (2005): Calcium signalling: Past, present and future. Cell Calcium, v. 38, p.161 - 169. 188. D. Burdakov, O.H. Petersen & A. Verkhratsky (2005): Intraluminal calcium as a primary regulator of endoplasmic reticulum function. Cell Calcium, v. 38, 303 - 310. A.Verkhratsky - Curriculum Vitae 31

189. S.A. Fedulova, A. Verkhratsky & N. Veselovsky (2004): Regulation of GABA release by depolarization-evoked Ca2+ transients at a single hippocampal terminal. Pflügers Archiv European Journal of Physiology, v. 448, p. 376 - 382. 190. N. Ismayilova, J. Brotchie, A. Verkhratsky & A. Crossman (2004): Effects of adenosine A1, dopamine D1 and metabotropic glutamate 5 receptors–modulating agents on locomotion of the reserpinised rats. European Journal of Pharmacology, v. 497, p. 187 - 195. 191. Xie Jiong, P.J. Camello, A. Verkhratsky & E. C. Toescu (2004): Mitochondrial polarisation status 2+ and [Ca ]i signalling in long-term cultures of rat cerebellar granule neurones. Neurobiology of Ageing, v. 25, p. 349 - 359. 192. A. Verkhratsky, M. Mattson & E.C. Toescu (2004): Aging in the mind. Trends in Neurosciences, v. 27, p.577 - 578. 193. E.C. Toescu, A. Verkhratsky & P. Landfield (2004): Calcium Regulation and Gene Expression in Normal Brain Aging. Trends in Neurosciences, v. 27, p. 614 - 620. 194. A. Verkhratsky & S.A. Fedulova (2004): Calcium entry and intracellular calcium stores in regulation of neurotransmitter release. Fiziologichnyi Zhournal, v. 50, p. 142 – 149 (in Ukrainian). 195. S. Wray, U. Ravens, A. Verkhratsky & D. Eisner (2004): Two centuries of excitation-contraction coupling. Cell Calcium, v. 35, 485 - 489. 196. A. Verkhratsky (2004): Endoplasmic reticulum calcium signalling in nerve cells. Biological Research, v. 37, p. 693 - 699. 197. E.C. Toescu & A. Verkhratsky (2004): Ca2+ and mitochondria as substrates for deficits in synaptic plasticity in normal brain ageing. Journal of Cellular and Molecular Medicine, v. 8, p. 181 - 190. 198. D. Brough, R A. Le Feuvre, R. D. Wheeler, N. Solovyova, S. Hilfiker, N. J. Rothwell & A. Verkhratsky (2003): Ca2+ stores and Ca2+ entry differentially contribute to the release of IL-1 and IL-1 from murine macrophages. Journal of Immunology, v. 170, p. 3029-3036. 199. T.-J. Huang, S. Price, L. Chilton, N.A. Calcutt, D.R. Tomlinson, A. Verkhratsky & P. Fernyhough (2003): Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of Type I diabetic rats in the presence of sustained hyperglycemia. Diabetes, v. 52, p. 2129-2136. 200. M. Ross, S. M. Allan, N. J. Rothwell & A. Verkhratsky (2003) A dual role for interleukin-1 in LTP in mouse hippocampal slices. Journal of Neuroimmunology, v.144. p. 61 - 67. 201. Yu. Pankratov, U. Lalo, O. Krishtal & A. Verkhratsky (2003): P2X receptor-mediated excitatory synaptic currents in somato-sensory cortex. Molecular & Cellular Neuroscience, v. 24, p. 842 - 849. 202. N. Solovyova & A. Verkhratsky (2003): Neuronal endoplasmic reticulum acts as a single functional Ca2+ store shared by ryanodine and inositol-1,4,5-trisphosphate receptors as revealed by intra-ER [Ca2+] recordings in single rat sensory neurones. Pflügers Archiv European Journal of Physiology, v. 446, p. 447 - 454. 203. E.C. Toescu & A. Verkhratsky (2003): Neuronal ageing from an intraneuronal perspective: roles of endoplasmic reticulum and mitochondria. Cell Calcium, v. 34, p. 311 - 323. 204. A. Verkhratsky & E. C. Toescu (2003): Endoplasmic reticulum Ca2+ homeostasis and neuronal death. Journal of Cellular and Molecular Medicine, v. 7, p. 351 - 361. 205. P. Fernyhough, Huang, T.Z. & A. Verkhratsky (2003): Mechanism of mitochondrial dysfunction in diabetic sensory neuropathy. Journal of the Peripheral Nervous System, v. 8, p. 227 - 235. 206. N. Solovyova, N. Veselovsky, E.C. Toescu & A. Verkhratsky (2002): Ca2+ dynamics in the lumen of the endoplasmic reticulum in sensory neurones: direct visualisation of Ca2+-induced Ca2+ release triggered by physiological Ca2+ entry. EMBO J., v. 21, p. 622 - 630. 207. J. Xiong, A. Verkhratsky & E. C. Toescu (2002): Changes in mitochondrial status associated with altered Ca2+ homeostasis in aged cerebellar granule neurones in brain slices. Journal of Neuroscience, v. 22, p. 10761 - 10771. A.Verkhratsky - Curriculum Vitae 32

208. T.-J. Huang, N. M. Sayers, P. Fernyhough & A. Verkhratsky (2002): Diabetes-induced alterations in calcium homeostasis in sensory neurones of streptozotocin-diabetic rats are restricted to lumbar ganglia and are prevented by neurotrophin-3. Diabetologia, v. 45, p. 560 - 570. 209. N. Solovyova, P. Fernyhough, G. Glazner & A. Verkhratsky (2002): Xestospongin C empties the 2+ ER calcium store but does not inhibit InsP3-induced Ca release in cultured dorsal root ganglia neurones. Cell Calcium, v. 32, p. 49 - 52.

210. Yu. Pankratov, U. Lalo, O. Krishtal & A. Verkhratsky (2002): Ionotropic P2X purinoreceptors mediate synaptic transmission in rat pyramidal neurons of layer II/III of somato-sensory cortex. Journal of Physiology (London), v. 542, p. 529 - 536. 211. D. V. Kiryushko, L. P. Savtchenko, A. Verkhratsky & S. M. Korogod (2002): Theoretical estimation of the capacity of intracellular calcium store in Bergmann glial cell. Pflügers Archiv European Journal of Physiology, v. 443, p. 643 - 651. 212. A. Verkhratsky (2002): The endoplasmic reticulum and neuronal calcium signalling. Cell Calcium, v. 32, 393 - 404. 213. M. D. Bootman, O. H. Petersen & A. Verkhratsky (2002): The endoplasmic reticulum is a focal point for co-ordination of cellular activity. Cell Calcium, v. 32, 231 - 234. 214. N. Solovyova, & A. Verkhratsky (2002): Monitoring of free calcium in the neuronal endoplasmic reticulum: An overview of modern approaches. Journal of Neuroscience Methods, v. 122, p. 1 - 12. 215. A. Verkhratsky, P.W. Landfield, P.W. & O. Thibault (2002): Calcium signaling and neuronal pathology. Preface. European Journal of Pharmacology, v. 447, 115-117. 216. A. Verkhratsky & O. H. Petersen (2002): The endoplasmic reticulum as an integrating signalling organelle: From neuronal signalling to neuronal death. European Journal of Pharmacology, v. 447, p. 141 - 154. 217. A. Verkhratsky & N. Solovyeva (2002): Alterations in the function of endoplasmic reticulum and neuronal signaling. Neurophysiology, v. 34, p. 131 - 136. 218. V. N. Dedov, S. Mandadi, P. J. Armati, & A. Verkhratsky (2001): The VR-1 vanilloid receptor sensitises mitochondria of dorsal root ganglia neurones to an uncoupling effect of capsaicin, mediated via inhibition of complex I of the respiratory chain. Neuroscience, v. 103, p. 219 - 226. 219. K.M. Schmidt-Ott, A.D. Xu, S. Tuschick, L. Liefeldt, W. Kresse, A. Verkhratsky, H. Kettenmann & M. Paul (2001): Hypoxia reverses dibutyryl-cAMP-induced stellation of cultured astrocytes via activation of the endothelin system. FASEB Journal, v. 15, p. 1227 - 1229. 220. E C. Toescu, A. Verkhratsky (2000): Neuronal ageing in long-term cultures: Alterations of Ca2+ homeostasis. NeuroReport, v. 11, p. 3725 - 3730. 221. E.C.Toescu & A. Verkhratsky (2000): Assessment of mitochondrial polarisation status in living cells based on analysis of spatial heterogeneity of Rhodamine 123 fluorescence staining. Pflügers Archiv European Journal of Physiology, v. 440, p. 941 - 947. 222. T. Möller, O. Kann, A. Verkhratsky & H. Kettenmann (2000): Activation of mouse microglial cells

affects P2 receptor signalling. Brain Research, v. 853, p. 49 - 59. 223. A. Minelli, S. Lyons, C. Nolte, A. Verkhratsky & H. Kettenmann (2000): Ammonium triggers calcium elevation in cultured microglial cells by initiating Ca2+ release from thapsigargin-sensitive intracellular stores. Pflügers Archiv European Journal of Physiology v. 439, p. 370 - 377. 224. E. Toescu & A. Verkhratsky (2000): Parameters of calcium homeostasis in normal neuronal ageing. Journal of Anatomy, v. 197, p. 563 - 569. 225. E.C. Toescu, N. Myronova & A. Verkhratsky (2000): Age-related structural and functional changes of brain mitochondria. Cell Calcium, v. 28, 329 - 338. 226. A. Verkhratsky & C. Steinhäuser (2000): Ion channels in glial cells. Brain Research Reviews, v. 32, p. 380 - 412. A.Verkhratsky - Curriculum Vitae 33

227. S. Kirischuk, F. Kirchhoff, V. Matyash, H. Kettenmann & A. Verkhratsky (1999): Glutamate- 2+ triggered Ca signalling in mouse Bergmann glial cells in situ: role of InsP3-mediated intracellular Ca2+ release. Neuroscience, v. 92, p.1051 - 1059. 228. J. Grosche, V. Matyash, T. Möller, A. Verkhratsky, A. Reichenbach & H. Kettenmann (1999): Microdomains for neurone-glia interaction: Parallel fiber stimulation signals to substructures of Bergmann glial cells. Nature Neuroscience, v. 2, p. 139 - 143. 229. D.F. Condorelli, F. Conti, V. Gallo, F. Kirchhoff, G. Seifert, C. Steinhäuser, A. Verkhratsky & X. Yuan (1999): Expression and functional analysis of glutamate receptors in glial cells. Advances in Experimental Medical Biology, v. 468, p. 49 - 67. 230. J. Hartmann & A. Verkhratsky (1998): Relations between intracellular Ca2+ stores and store- operated Ca2+ entry in primary cultured human glioblastoma cells. Journal of Physiology, London, v. 513, p. 411 - 424. 231. E. C. Toescu, T. Möller, H. Kettenmann & A. Verkhratsky (1998): Long-term activation of capacitative Ca2+ entry in mouse microglial cells. Neuroscience, v. 86, p. 925 - 935. 232. K.M. Schmidt-Ott, S. Tuschick, F. Kirchoff, A. Verkhratsky, L. Liefeldt, H. Kettenmann & M. Paul (1998): Single-cell characterization of endothelin system gene expression in the cerebellum in situ. Journal of Cardiovascular Pharmacology, v. 31, Suppl. 1, p. S364 - S366. 233. A. Verkhratsky & O.H. Petersen (1998): Neuronal calcium stores. Cell Calcium, v. 24, p. 333 - 343. 234. J.W. Deitmer, A. Verkhratsky & C. Lohr (1998): Calcium signalling in glial cells. Cell Calcium, v. 24, p. 405 - 416. 235. A. Verkhratsky & E.C. Toescu (1998): On slices, synaptosomes and dissociated neurones to study in vitro ageing physiology. Trends in Neurosciences, v. 21, p. 286 - 287. 236. A. Verkhratsky & E.C. Toescu (1998): Calcium and neuronal ageing. Trends in Neurosciences, v. 21, p. 2 - 6. 237. A. Verkhratsky, R. Orkand & H. Kettenmann (1998): Glial calcium: homeostasis and signalling function. Physiological Reviews, v. 78, p. 99 - 141. 238. T. Möller, C. Nolte, R. Burger, A. Verkhratsky & H. Kettenmann (1997): Mechanisms of C5a and 2+ C3a complement-fragments induced [Ca ]i signalling in mouse microglia. Journal of Neuroscience, v. 17, 615 - 624. 239. S. Kirischuk, H. Kettenmann & A. Verkhratsky (1997): Na+/Ca2+ exchanger modulates kainate- triggered Ca2+ signalling in Bergmann glial cells in situ. FASEB Journal, v. 11, p. 566 - 572. 240. N. Svichar, P. Kostyuk & A. Verkhratsky (1997): Mitochondria buffer Ca2+ entry but not intracellular Ca2+ release in mouse DRG neurones. NeuroReport, v. 8, p. 3929-3932. 241. S. Tuschick, S. Kirischuk, F. Kirchhoff, L. Liefeldt, M. Paul, A. Verkhratsky & H. Kettenmann

(1997): Bergmann glial cells in situ express endothelinB receptors linked to cytoplasmic calcium signals. Cell Calcium, v. 21, p.408 - 419 2+ 242. N. Svichar, A. Shmigol, A. Verkhratsky & P. Kostyuk (1997): ATP induces Ca release from InsP3- sensitive Ca2+ stores exclusively in large DRG neurones. NeuroReport, v. 8, p. 1555-1559. 243. T. Möller, O. Kann, M. Prinz, F. Kirchhoff, A. Verkhratsky & H. Kettenmann (1997): Endothelin

induced calcium signaling in cultured mouse microglial cells is mediated through ETB receptors. NeuroReport, v. 8, p. 2127-2131. 2+ 244. N. Svichar, A. Shmigol, A. Verkhratsky & P. Kostyuk (1997): InsP3-induced Ca release in dorsal root ganglion neurones. Neuroscience Letters, v. 227, p. 107-110. 245. V. Matyash & A.Verkhratsky (1997): Expression of type I metabotropic glutamate receptors in Purkinje neurones of mice. Neurophysiology (Kiev), v. 29, p. 1- 4. A.Verkhratsky - Curriculum Vitae 34

246. V. Matyash, S. Kirischuk & A.Verkhratsky (1997): Expression and functional properties of glutamate receptors in Bergmann glial cells in situ. Journal of Academy of Medical Sciences of the Ukraine, v. 3, p. 100 - 111 (in Ukrainian). 247. A. Verkhratsky (1997): Calcium signalling in glial cells. Neurophysiology (Kiev), v. 29, p. 263 - 272. 248. S. Kirischuk & A. Verkhratsky (1996): Calcium homeostasis in aged neurones. Life Sciences, v. 59, p. 451 - 459. 249. S. Kirischuk, V. Matiash, A. Kulik, N. Voitenko, P. Kostyuk & A. Verkhratsky (1996): Activation of

P2-purino-, 1-adreno- and H1-histamine receptors triggers cytoplasmic calcium signalling in cerebellar Purkinje neurones. Neuroscience, v. 73, p. 643 - 647. 250. S. Haas, J. Brockhaus, A. Verkhratsky & H. Kettenmann (1996): ATP-induced membrane currents in ameboid microglia acutely isolated from mouse brain slices. Neuroscience, v. 75, p. 257 - 261. 251. S. Kirischuk, S. Tuchek, A. Verkhratsky & H. Kettenmann (1996) Calcium signalling in mouse

Bergmann glial cells mediated by 1-adrenoreceptors and H1 histamine receptors European Journal of Neurosciences, v. 8, p. 1198-1208. 2+ 252. S. Kirischuk & A. Verkhratsky (1996): [Ca ]i recordings from neural cells in acutely isolated cerebellar slices employing differential loading of membrane permeant form of calcium indicator fura-2. Pflügers Archiv European Journal of Physiology, v. 431, p. 977 - 983. 253. S. Kirischuk, N. Voitenko, P. Kostyuk & A. Verkhratsky (1996): Calcium signalling in granule neurones studied in cerebellar slices. Cell Calcium, v. 19, p. 59-71. 254. A. Shmigol, N. Svichar, P. Kostyuk & A. Verkhratsky (1996): Gradual caffeine-induced Ca2+ release in mouse dorsal root ganglion neurons is controlled by cytoplasmic and luminal Ca 2+. Neuroscience, v. 73, p. 1061 - 1067. 255. S. Kirischuk, N. Voitenko, P. Kostyuk & A. Verkhratsky (1996): Age-associated changes of cytoplasmic calcium homeostasis in cerebellar granule neurons in situ: investigation on thin cerebellar slices. Experimental Gerontology, v. 31, p. 475 - 487. 256. A. Verkhratsky & H. Kettenmann (1996): Calcium signalling in glial cells. Trends in Neurosciences, v. 19, p. 346 - 352. 257. A. Verkhratsky & A. Shmigol (1996): Calcium-induced calcium release in nerve cells. Cell Calcium, v. 19, p. 1 - 14. 258. A. Shmigol, A. Verkhratsky & G. Isenberg (1995): Calcium-induced calcium release in rat sensory neurones. Journal of Physiology (London), v. 489, p.627-636. 259. S. Kirischuk, T. Möller, N. Voitenko, H. Kettenmann & A. Verkhratsky (1995): ATP-induced cytoplasmic calcium mobilization in Bergmann glial cells. Journal of Neuroscience, v. 15, p. 7861- 7871. 260. S. Kirischuk, J. Scherer, A. Verkhratsky & H. Kettenmann (1995): Subcellular heterogeneity of voltage-gated Ca2+ channels in cells of the oligodendrocyte lineage. Glia, v. 13, p. 1 - 12. 261. S. Kirischuk, J. Scherer, H. Kettenmann & A. Verkhratsky (1995): Activation of P2-purinoreceptors 2+ triggered Ca release from InsP3-sensitive internal stores in mammalian oligodendrocytes. Journal of Physiology, London, v. 483, p. 41 - 57. 262. A. Shmigol, P. Kostyuk & A. Verkhratsky (1995): Dual action of thapsigargin on calcium mobilization in sensory neurones: inhibition of Ca2+ uptake by caffeine-sensitive internal pools and blockade of plasmalemmal Ca2+ channels. Neuroscience, v. 65, p. 1109 - 1118. 263. Yu. Usachev & A. Verkhratsky (1995): IBMX-induces Ca2+ release from ryanodine-sensitive Ca2+ stores in adult rat sensory neurones. Cell Calcium v. 17, p. 197-206 264. M. Kano, O. Garaschuk, A. Verkhratsky & A. Konnerth (1995): Ryanodine receptor-mediated intracellular calcium release in rat cerebellar Purkinje neurones. Journal of Physiology, London, v. 487, p. 1 - 16 A.Verkhratsky - Curriculum Vitae 35

265. Yu. Usachev, P. Kostyuk & A.Verkhratsky (1995): 3-Isobutyl-1-methylxanthine (IBMX) affects potassium permeability in rat sensory neurones via pathways that are sensitive and insensitive to 2+ [Ca ]in. Pflügers Archiv European Journal of Physiology, v. 430, p.420 - 428. 266. S. Kirischuk, J. Neuhaus, A. Verkhratsky & H. Kettenmann (1995): Preferential localization of active mitochondria in process tips of immature retinal oligodendrocytes. NeuroReport, v. 6, 737 - 741 267. M. Kano, R. Schneggerburger, A.Verkhratsky & A. Konnerth (1995): Depolarization-induced calcium signals in the somata of cerebellar Purkinje neurones. Neuroscience Research, v. 24, p. 87-95. 268. A. Shmigol, S. Kirischuk, P. Kostyuk & A. Verkhratsky (1994): Different properties of caffeine- sensitive calcium stores in rat peripheral and central neurones. Pflügers Archiv European Journal of Physiology, v. 426, p. 174 - 176. 269. A. Shmigol, P. Kostyuk & A. Verkhratsky (1994): Role of caffeine-sensitive Ca2+ stores in Ca2+ signal termination in adult mouse DRG neurones. NeuroReport, v. 5, 2073 - 2076. 270. A. Shmigol, Yu. Usachev, N. Pronchuk, S. Kirischuk, P. Kostyuk & A. Verkhratsky (1994): Properties of the caffeine sensitive intracellular calcium stores in mammalian neurones. Neurophysiology (Kiev), v. 26 No. 2, p. 16 - 25. 271. S. Kirischuk, H. Kettenmann & A. Verkhratsky (1994): Calcium signalling in oligodendrocytes. Neurophysiology (Kiev), v. 26 No. 2, p. 26 - 31. 272. S. Kirischuk, N. Voitenko, H. Kettenmann & A. Verkhratsky (1994) Mechanisms of cytoplasmic calcium signalling in cerebellar Bergmann glial cells. Neurophysiology (Kiev), v. 26, p. 417 - 419. 273. Yu. V. Usachev, A.V. Shmigol, N.F. Pronchuk, A.N. Verkhratsky (1994) The role of a caffeine- sensitive calcium depot in modulating calcium signals in rat sensory neurones Doklady Akademii Nauk, v. 334, p. 381 - 384 (in Russian). 274. P. Kostyuk & A. Verkhratsky (1994): Calcium stores in neurones and glial cells. Neuroscience, v. 63, 381 - 404. 275. A. Verkhratsky, A. Shmigol, S. Kirischuk, N. Pronchuk & P. Kostyuk (1994): Age-dependent changes in calcium currents and calcium homeostasis in mammalian neurones. Annals of the New York Academy of Sciences, v. 747, p 365 - 381. 276. P. Kostyuk, N. Pronchuk, A. Savchenko & A. Verkhratsky (1993): Calcium currents in aged rat sensory neurones. Journal of Physiology, London, v. 461, p. 467 - 483. 277. Yu. Usachev, A. Shmigol, N. Pronchuk, P. Kostyuk & A. Verkhratsky (1993): Caffeine-mediated increase of intracellular calcium in cultured rat sensory neurones. Neuroscience, v. 57, p. 845 - 859 278. V.G. Shevchuk, A.V. Shmigol, A.N. Verkhratsky & I.N. Karvatski (1993): Effect of caffeine on chronotropic correlations in the myocardium of the rat and guinea pig. Fiziol. Journal, v. 39, p. 97 - 100 (in Russian). 279. G. von Blankenfeld, A.N. Verkhratsky & H. Kettenmann (1992): Expression of voltage-activated calcium currents in olygodendrocytes and their precursors: Developmental changes. European Journal of Neuroscience, v. 4, p. 1035 - 1049 280. S. Kirischuk, N. Pronchuk & A. Verkhratsky (1992): Measurements of intracellular calcium in sensory neurones of adult and old rats. Neuroscience, v. 50, p. 947 - 951. 281. P. Kostyuk, A. Savtchenko, E. Molokanova, N. Pronchuk & A. Verkhratsky (1992): Ethosuccimide selectively blocks low-threshold calcium currents in sensory neurones. Neuroscience, v. 51, p. 755 - 758. 282. A.V. Shmigol, V.G. Shevchuk, I.N. Karvatskii & A.N. Verkhratsky (1992): Caffeine eliminates the positive inotropic effect of paired stimulation in the myocardium of warm-blooded animals. Dokl. AN SSSR, v. 332, p. 1078 - 1082 (in Russian). A.Verkhratsky - Curriculum Vitae 36

283. A.N. Verkhratsky (1992): Molecular mechanisms of calcium channels regulation in cardiac muscle. Uspekhi Physiol. Nauk, v. 23, No. 1, p. 1 - 19 (in Russian). 284. A. Verkhratsky, D. Hoppe & H.Kettenmann (1991): Single K+ channel properties in cultured mouse Schwann cells: Conductance and kinetics. Journal of Neuroscience Research, v. 28, p. 200 - 209. 285. A. Verkhratsky, D. Hoppe & H. Kettenmann (1991) K+ channel properties in cultured mouse Schwann cells: dependence on extracellular K+. Journal of Neuroscience Research, v. 28, p. 210-216. 286. A.N. Verkhratsky, N.F. Pronchuk & A.N. Savtchenko (1991): Lack of the low-threshold calcium channels in the membrane of single cultured neonatal rat ventricular myocytes. Fiziol. Zjournal, v. 37, p. 25 - 31 (in Russian). 287. A.N. Verkhratsky, N.F. Pronchuk & A.N. Savtchenko (1991): The characteristics of the sodium currents across EGTA-modified calcium channels in the membrane of cultured rat cardiomyocytes. Fiziol. Zjournal, v. 37, p. 49 - 53 (in Russian). 288. N.A. Burnashev, F.A. Edwards & A.N. Verkhratsky (1991): Thin myocardial slices: new tool for single-channel currents measurements. Fiziol. Zjournal, v. 37, p. 119 - 122 (in Russian). 289. N.A. Burnashev, F.A. Edwards & A.N. Verkhratsky (1991): The recording of single sodium and potassium channel currents on slices of heart muscle. Dokl. AN SSSR, v. 318, p. 481 - 484 (in Russian). 290. A.E. Valeev, A.N. Verkhratsky & F.N. Dzhakhangirov (1991): Effects of allapinin on sodium currents in isolated neurons of the trigeminal ganglia and cardiomyocytes of rats. Biulleten Eksperimentalnoi Biologii i Medicini, v. 111, p. 388 - 390. 291. A.N. Savtchenko & A.N. Verkhratsky (1990): Omega-conotoxin blockade of calcium currents in cultured neonatal rat cardiomyocytes: Different action on EGTA-modified calcium channels. General Physiology & Biophysics, v. 9, No. 2, p. 147 - 166. 292. A.N. Verkhratsky, J. Trotter & H. Kettenmann (1990): Cultured glial precursor cells from mouse cortex express two types of calcium currents. Neuroscience Letters, v. 112, p. 194 - 198. 293. N.A. Burnashev, F.A. Edwards & A.N. Verkhratsky (1990): Patch-clamp recordings on rat cardiac muscle slices. Pflügers Archiv European Journal of Physiology, v. 417, p. 123 - 125. 294. A.N. Verkhratsky & V.I. Pidoplichko (1990): The effect of the acidification of the extracellular medium on the membrane sodium currents of single heart cells. Fiziol Zh SSSR Im I M Sechenova, v. 76, No. 1, p. 87 - 91 (in Russian). 295. A.N. Verkhratsky & A.N. Savchenko (1990): Omega-conotoxin block calcium current in a membrane of cultured rat cardiocytes. Dokl. AN SSSR, v. 310, No. 3, p. 747 - 750 (in Russian). 296. A.N. Verkhratsky & A.N. Savchenko (1990): Differences in time parameters of omega-conotoxin blockade of calcium channels of cultured rat cardiomyocytes depending on a penetrating cation species. Biologicheskie Membrany, v. 7, No. 2, p. 176 - 187 (in Russian). 297. N. Ch. Pogorelaya, A. N. Savtchenko, Ya. M. Shuba & A. N. Verkhratsky (1990): Two components of the high-threshold calcium current with different sensitivity to omega-conotoxin in the membrane of pheochromocytoma cells. Neurofiziologia, v. 22, p. 397 - 400 (in Russian). 298. A. E. Valeev, A. N. Verkhratsky & F. N. Dzhihangirov (1990): Allapinine influence on sodium currents of isolated neurones of trigeminal ganglion and cardiomyocytes of rats. Neurofiziologia, v. 22, p. 201 - 206 (in Russian). 299. V.I. Pidoplichko & A.N. Verkhratsky (1989): Use-dependent blocking of sodium current in the membrane of single rat cardiomyocytes by calcium antagonist verapamil. Fiziol. Zjournal, v. 35, No. 2, p. 87 - 89 (in Russian). 300. P. V. Belan, A. N. Verkhratsky, N. F. Pronchuk, & A. V. Tepikin (1989): Application of microfluorometry method to measure free calcium in isolated cultured rat cardiac myocytes. Fiziol. Zjournal, v. 35, No. 6, p. 39 - 46 (in Russian). A.Verkhratsky - Curriculum Vitae 37

301. A. N. Verkhratsky, N. F. Pronchuk, & A. V. Tepikin (1989): The effect of sodium ion extracellular concentration on intracellular calcium ion concentration in single neonatal rat cultured ventricular myocytes. Fiziol. Zjournal, v. 35, No. 6, p. 45 - 49 (in Russian). 302. V. I. Pidoplichko & A. N. Verkhratsky (1987): Possible existence of transient TTX-sensitive chloride current in the membrane of isolated cardiomyocytes. General Physiology & Biophysics, v. 6, p. 223 - 235. 303. A. N. Verkhratsky & V. I. Pidoplichko (1987): Two-component character of sodium inward current in the membrane of isolated cardiomyocytes. Fiziol. Zjournal, v. 33, No. 4, p. 44 - 48 (in Russian). 304. V. I. Pidoplichko & A. N. Verkhratsky (1987): Sodium currents in the membrane of isolated cardiomyocytes. Biomed. Biochim. Acta, v. 46, No. 8/9, p. S668 - S672. 305. V. I. Pidoplichko & A. N. Verkhratsky (1987): Separation of the fast sodium current components in the membrane of isolated cardiac muscle cells. Dokl. AN Ukrainian SSR, No. 4, p. 78 - 81 (in Ukrainian). 306. A. N. Verkhratsky & V.I.Pidoplichko (1987): Ionic currents in the membrane of isolated cardiac muscle cells. Uspekhi Physiol. Nauk, v. 18, No. 1, p. 23 - 42 (in Russian). 307. A. N. Verkhratsky (1986): Cadmium ions blockade of sodium currents in the membrane of isolated cardiomyocytes. Fiziol. Zjournal, v. 32, No. 4, p. 476 - 478 (in Russian). 308. V. I. Pidoplichko & A. N. Verkhratsky (1986): The paradoxical influence of extracellular sodium lowering on the inward current parameters in the membrane of isolated cardiomyocytes. Fiziol. Zjournal, v. 32, No. 1, p. 50 - 53 (in Russian). 309. V. I. Pidoplichko & A. N. Verkhratsky (1986): Fluoride ions can generate current through the membrane of isolated perfused cardiomyocytes. Dokl. AN SSSR, v. 286, No. 1, p. 232 - 235 (in Russian). 310. A. N. Verkhratsky & V.I. Pidoplichko (1985): Tetrodotoxin-sensitive, pH-dependent chloride current in the membrane of isolated cardiomyocytes. Biologicheskie Membrany, v. 2, No. 1, p. 17 - 24 (in Russian). 311. V. I. Pidoplichko & A. N. Verkhratsky (1984): Possible existence of the tetrodotoxin-sensitive voltage-dependent chloride permeability in the membrane of perfused cardiomyocytes. Dokl. AN SSSR, v. 279, No. 4, p. 1012 - 1015 (in Russian).

D. Chapters

312. A. Verkhratsky & M. Noda (2014): General physiology and pathophysiology of microglia. In: Neuroinflammation and Neurodegeneration, Edited by P.K. Peterson and M. Toborek; Springer Science+Business Media, New York, doi: 10.1007/978-1-4939-1071-7_3. 313. A. Verkhratsky & V. Parpura (2014): General pathophysiology of neuroglia: Neurological and psychiatric disorders as gliopathies. In: Pathological potential of neuroglia: Possible new targets for medical intervention. Ed by V. Parpura & A. Verkhratsky, Springer-Verlag, in press. 314. A. Verkhratsky & V. Parpura (2014): Ionic signalling in physiology and pathophysiology of astroglia. In: Pathological potential of neuroglia: Possible new targets for medical intervention. Ed by V. Parpura & A. Verkhratsky, Springer-Verlag, in press. 315. A. Verkhratsky & V. Parpura (2014): Neurodegeneration and neuroglia: Emphasis on astroglia in Alzheimer's disease, In: Pathological potential of neuroglia: Possible new targets for medical intervention. Ed by V. Parpura & A. Verkhratsky, Springer-Verlag, in press. A.Verkhratsky - Curriculum Vitae 38

316. A. Verkhratsky & G. Burnstock (2014): Purinergic and glutamatergic receptors on astroglia. In: V. Parpura, A. Schousboe & A. Verkhratsky, Eds. (2014): Glutamate and ATP at interface of metabolism and signalling. Springer-Verlag, in press. 317. A. Verkhratsky & V. Parpura (2013): Calcium signalling in neuroglia. In: Neuroglia, 3rd edition, Ed. by H. Kettenmann &. B.R. Ransom, Oxford University Press, 320 - 332. 318. M. Noda & A. Verkhratsky (2013): Physiology of microglia. In: Neuroglia, 3rd edition, Ed. by H. Kettenmann &. B.R. Ransom, Oxford University Press, p. 223 - 237. 319. H. Kettenmann & A. Verkhratsky (2012): Glial Cells. In: Neuroscience in the 21st Century, Ed. by D.W. Pfaff, Springer Science+Business Media, p. 475 - 506, doi: 10.1007/978-1-4614-1997-6_19. 320. A. Verkhratsky & V. Parpura (2013): In: Gap Junctions in the Nervous System: Physiological and Pathological Roles, Ed. by E. Dere, Elsevier, p. 51 - 68. 321. A. Verkhratsky, V. Parpura & H. Kettenmann (2012): Astrocytes. In: Encyclopedia of Neurological Sciences, 2nd edition, Ed. by M. J. Aminoff & R. B. Daroff, Elsevier, in press. 322. J. J. Rodríguez & A. Verkhratsky (2012): Neuroglial integrity and neurodegenerative disorders. In: Research Progress in Alzheimer's Disease and Dementia, Ed. by Miao-Kun Sun, Nova Publishers, Hauppauge NY, p. 141-171. 323. J. J. Rodríguez, C. Matute & A. Verkhratsky (2011): Neuroglia in Alzheimer’s Disease. In: Astrocytes: Wiring the Brain, Ed. by E. Schemes & D.C. Spray, Taylor & Francis Inc., p. 311 - 337. 324. A. Verkhratsky & O. H. Petersen (2010): Principles of the Ca2+ homeostatic/signalling system. In: Calcium imaging in neurobiology. Ed. by A. Verkhratsky & O.H. Petersen, Humana Press, p. 1 - 11. 325. R. Blum, O. H. Petersen & A. Verkhratsky (2010): Calcium imaging of intracellular organelles: endoplasmic reticulum. In: Calcium imaging in neurobiology. Ed. by A. Verkhratsky & O.H. Petersen, Humana Press, p. 147 - 167. 326. G. Eichhoff, Y. Kovalchuk, Z. Varga, A. Verkhratsky & O. Garaschuk (2010): In vivo Ca2+ imaging of the living brain using multi cell bolus loading technique. In: Calcium imaging in neurobiology. Ed. by A. Verkhratsky & O.H. Petersen, Humana Press, p. 205 - 220. 327. A. Verkhratsky (2009): Endoplasmic Reticulum Calcium Homeostasis and Neuronal Pathophysiology of Stroke. In: New Strategies in Stroke Intervention: Ionic Transporters, Pumps and New Channels, Ed. By L. Annunziato, Springer-Verlag, p. 47 - 64. 328. A. Verkhratsky & A. Reichenbach (2009): Bergmann Glia. In: Encyclopaedia of Neuroscience, 4th edition, p. 161 - 171. 329. A. Verkhratsky & O. A. Krishtal (2009): ATP as a neurotransmitter, In: Encyclopaedia of Neuroscience, 4th edition, p. 115 - 123. 330. A. Verkhratsky (2009): Neurotransmitter receptors in astrocytes. In: Astrocytes in (patho)physiology of the nervous system, Ed. by V. Purpura & P. Haydon, Springer-Verlag, p.49 - 67. 331. A. Verkhratsky (2007): Calcium and Cell Death. In: Calcium Signalling and Disease. Ed by E. Carafoli & M. Brini, Springer, Heidelberg, p. 465 - 480. 332. A. Verkhratsky (2007): Introduction to the Nervous System. In: Lecture Notes on Human Physiology, Ed. by O. H. Petersen, Blackwells, in press 333. A. Verkhratsky (2005): Endoplasmic reticulum and neuronal Ca2+ signalling. In: Receptors, Channels & Messengers, Ed. by P.G. Kostyuk, DUS, Kiev, p. 98 - 109. 334. N. Solovyova & A. Verkhratsky (2004): Measurements of free Ca2+ concentration in the lumen of neuronal endoplasmic reticulum. In: Imaging Neuroscience, Ed. by R. Yuste & A. Konnerth, Cold Spring Harbor Laboratory Press, p. 319 - 323. 335. A. Verkhratsky (2003): Neurones and glia in cross-talk: Role of chemical and electrical synapses. In: 3rd FEPS Congress Proceedings, Ed. by P. Poujeol & O.H. Petersen, Monduzzi Editore, Bologna, p. 95 - 102. A.Verkhratsky - Curriculum Vitae 39

336. A. Verkhratsky, N. Solovyeva & E.C. Toescu (2002): Calcium excitability of glial cells. In: Glia in synaptic transmission, Ed. by A. Volterra, P. Haydon & P. Magistretti, OUP, p. 91 - 109. 337. A. Verkhratsky & O. Jones (2002): Astrocytic networks and brain injury. In: Immune and inflammatory responses in the nervous system, Ed. by N. Rothwell and S. Loddick, OUP p.24 - 35. 338. A. Verkhratsky (2001): Glial calcium signalling and neuronal-glial interactions. In Calcium Signalling, Ed. By M. Morad & P. Kostyuk, p. 137 - 144. 339. E.C. Toescu & A. Verkhratsky (2001): Principles of Fluorescence Measurements - Dyes and Hardware Required. In: Measuring Calcium and Calmodulin Inside and Outside Cells, Ed. by O.H. Petersen, Springer-Verlag p. 3 - 45. 340. A. Verkhratsky & E.C. Toescu (2000): Calcium and cellular ageing. In: Calcium and Cellular Function, Ed. By R. Pochet, Kluwer, p. 277 - 286. 341. E.C. Toescu & A. Verkhratsky (2000): Calcium and Neuronal Ageing. Differences between normal ageing and neurodegeneration. In: Alzheimer European Yearbook, p. 271 - 276. 342. E.C. Toescu & A.Verkhratsky (1998): Principles of calcium signalling. In: Integrative Aspects of Calcium Signalling, Plenum Press, p. 2 - 22. 343. P. Kostyuk & A. Verkhratsky (1998): Basic properties of calcium release channels in neural cells. In: Pharmacology of Ion Channels, Ed. by B. Soria, Oxford University Press, Oxford et al. p. 299 - 320. 344. F.N. Dzhihangirov, A.E. Valeev & A.N. Verkhratsky (1993): Allapinin – New antiarrhythmic plant agent. “FAN”, Taskent, p. 1 - 34 (in Russian).

E. Web lectures 345. A. Verkhratsky & V. Parpura, Eds. (2011): Physiology and Pathophysiology of Neuroglia, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London 346. A. Verkhratsky (2011): "Where the thoughts dwell: history of neuroscience and introduction into neuroglia", in Verkhratsky, A. and Parpura, V. (Eds.), Physiology and Pathophysiology of Neuroglia, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://hstalks.com/?t=BL1272960-Verkhratsky) 347. A. Verkhratsky (2011), "Cell biology and physiology of astroglia", in Verkhratsky, A. and Parpura, V. (Eds.), Physiology and Pathophysiology of Neuroglia, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://hstalks.com/?t=BL1272961-Verkhratsky) 348. A. Verkhratsky (2011), "Glial calcium signalling", in Verkhratsky, A. and Parpura, V. (Eds.), Physiology and Pathophysiology of Neuroglia, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://hstalks.com/?t=BL1272962-Verkhratsky) 349. A. Verkhratsky (2011), "Neuronal-glial chemical transmission mediated by glutamate and ATP", in Verkhratsky, A. and Parpura, V. (Eds.), Physiology and Pathophysiology of Neuroglia, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://hstalks.com/? t=BL1272963-Verkhratsky) 350. A. Verkhratsky (2011), "Astroglia in neuropathology", in Verkhratsky, A. and Parpura, V. (Eds.), Physiology and Pathophysiology of Neuroglia, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://hstalks.com/?t=BL1272992-Verkhratsky). 351. A. Verkhratsky (2007): "Physiology and Pathophysiology of the Calcium Store in the Endoplasmic Reticulum of Neurones", in Michalak, M. (Ed.),The Endoplasmic Reticulum: Fundamentals and Role in Disease, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://www.hstalks.com/?t=BL0121343-Verkhratsky). A.Verkhratsky - Curriculum Vitae 40

F. Editorials & Commentaries

352. S. Muallem & A. Verkhratsky (2013) The art of physiology in the hands of the master: The Calcium community celebrates the 70th birthday of Ole Holger Petersen. Cell Calcium, v. 53, p. 303 - 306. 353. M. Nedergaard & A. Verkhratsky (2013): The birth of the journal: The first anniversary of WIREs MTS. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, v. 2, p. 105. 354. M.P. Abbracchio, J. M. Boeynaems, M. Cattaneo, F. D. Virgilio, P. Illes, K. Inoue, K. A. Jacobson, M. Teresa Miras-Portugal, V. Ralevic, S. C. Robson, A. Verkhratsky, & H. Zimmermann. (2013): Reply To: 'The Discovery of a New Class of Synaptic Transmitters in Smooth Muscle Fifty Years Ago and Amelioration of Coronary Artery Thrombosis." Acta Physiologica (Oxford), v. 208, p. 139 - 140. 355. V. Parpura & A. Verkhratsky (2012): Neuroglia at the crossroads of homeostasis, metabolism and signaling: Evolution of the concept. ASN Neuro, 4, p. e00087. 356. G. Burnstock & A. Verkhratsky (2012): Omnipresent purinergic signaling: an editorial essay. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, v. 1, p. 113 - 115. 357. A. Verkhratsky & M. Nedergaard (2012): Supporting the cell, supporting the science: an editorial essay. Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, v. 1, p. 1 - 2. 358. H. De Smedt, A. Verkhratsky & S. Muallem (2011): Ca2+ signaling mechanisms of cell survival and cell death: An introduction. Cell Calcium, v. 50, p. 207 - 210. 359. A. Verkhratsky & J.J. Rodriguez (2010): The Achilles heel of -secretase: Can we contain Alzheimer's disease by reducing synthesis of beta-amyloid? Acta Pharmacologica Sinica, v. 31, p. 1407 - 1408. 360. R. A. Knight & A. Verkhratsky (2010): Neurodegenerative diseases: Failures in brain connectivity? Cell Death & Differentiation, v. 17, p. 1069-1070. 361. A. Verkhratsky, R. A. North, O. H. Petersen & O. Krishtal (2010): In memoriam: Platon Kostyuk (1924–2010), Cell Calcium, v. 48, p. 91 - 93. 362. A. Verkhratsky & O.H. Petersen (2010): Bernd Nilius: The Bard of ion channels. Congratulations on 65th birthday. Pflügers Archiv European Journal of Physiology, v. 460, p. 691 - 694. 363. B.B. Fredholm & A. Verkhratsky (2010): Purines – 80 years and very much alive. Acta Physiologica (Oxford), v.199, p 91-92. 364. M. Nedergaard, & A. Verkhratsky (2010): Calcium dishomeostasis and pathological calcium signalling in neurological diseases. Cell Calcium, v. 47, p. 101 - 102. 365. A. Verkhratsky (2009): Filming the glial dreams: Real time imaging of cannabionoid receptors trafficking in astrocytes. ASN Neuro, v. 1, e00023. 366. G. Burnstock, M. P. Abbracchio, S. Lewis, A. Verkhratsky & H. Zimmermann (2009): The expanding field of purinergic signalling. Trends in Neurosciences, v. 32, p. 1. 367. A. Verkhratsky & A. Hague (2009): The Cell Death Forum. Cell Death & Differentiation, v. 16, p. 359. 368. A. Hague & A. Verkhratsky (2009): Cell death mechanisms: life in the balance. Cell Death & Differentiation, v. 16, p. 512 - 514. 369. E.C. Toescu & A. Verkhratsky (2007): Role of calcium in normal aging and neurodegeneration. Aging Cell v. 6, p. 265. 370. A. Verkhratsky (2006): Toni Scarpa—25 years at the helm. Cell Calcium, v. 39, p. 1. 371. E.C. Toescu, A. Verkhratsky & M.P. Mattson (2004): Synaptic function and behaviour during normal ageing. Ageing Research Reviews, v. 3, p. v. A.Verkhratsky - Curriculum Vitae 41

372. A. Verkhratsky & O.H. Petersen (1998): Intracellular calcium signalling in the nervous system. Preface. Cell Calcium, v. 24, p. 305. 373. P.G. Kostyuk & A.N. Verkhratskii (1991): Second Soviet-Spanish symposium on physical-chemical biology: Biological membranes – Structure and function. Biologicheskie Membrany, v. 8, p. 892 - 894.

G. Other publications

374. J.J. Rodríguez & A. Verkhratsky (2009): Rafael Lorente de No (1902 – 1990): The pioneer of physiological neuroanatomy. FEPS Newsleter 2009 #24, p. 5 - 9.

375. A. Verkhratsky (2008): The Holy Grail of Ion Channel: the two centuries quest. HekaImpulse, v. 4, p. 2 - 4.

376. N. Fedirko & A. Verkhratsky (2007): Physiology in Galicia. Physiology News, No. 68, p. 5 - 6.

377. A. Verkhratsky (1999): Impact factors & their role in the life of Scientist. The Physiological Society Magazine, No. 34, p. 6 - 7.

378. E. Toescu & A. Verkhratsky (1999): Talking telephone numbers... and brain ageing. The Physiological Society Magazine, No. 37, p. 14 - 15.

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