New England Orthopedic Center

EDUCATION & EMPLOYMENT______2010-Present President, New England Orthopaedic Center, LLC Torrington, CT 06790 2007 – 2010 Attending, Orthopaedic Surgery Litchfield Hills Orthopaedic Associates, LLP Torrington, CT 06790 2006-2007 Fellow, Foot & Ankle Surgery John Dempsey Hospital. Farmington, CT Hartford Hospital. Hartford, CT 2001-2006 Residency, Orthopaedic Surgery University of Connecticut. Farmington, CT 1997-2001 University of Louisville School of Medicine Doctor of Medicine, Cum Laude. Louisville, KY 1996-1997 Boston University School of Public Health M.P.H., Epidemiology and Biostatistics. Boston, MA. 1995-1997 Boston University School of Medicine M.A., Medical Science, Molecular Biology. Boston, MA. 1990-1994 Northwestern University B.A., Chemistry. Evanston, IL.

PRIVILEGES, LICENSURE, CERTIFICATIONS ______2010 – Board Certified, American Board of Orthopaedic Surgeons 2007 - Present Charlotte-Hungerford Hospital. 2008 - Present Bristol Hospital. 2006 - Present CT State Medical License.

PROFESSIONAL & HONORARY MEMBERSHIPS______2009- Present Connecticut State Orthopaedic Society. Board member. 2009- Present Orthopaedic Research Society. Member. 2001- Present American Academy of Orthopaedic Surgeons. Associate Member. 2000- Present AOA Honor Medical Society. Lifetime member. 1999- Present Ruth Jackson Orthopaedic Society. Past Nominating Committee member. 1997- Present Phi Delta Epsilon. Honor Medical Society. Lifetime member.

HONORS AND AWARDS______2009, 2011- Doctor of the Year Nominee. In recognition of physician excellence at Charlotte-Hungerford Hospital. Torrington, CT. 2006 Pyrtek Research Award. Suma Cum Laude. Hartford Hospital. Awarded in recognition of outstanding resident research. 2006 Ruth Jackson Orthopaedic Society Research Grant. Recipient of $30,000 grant to study effects of Tantalum on human osteoblasts. 2000 Alpha Omega Alpha Honor Medical Society. Elected lifetime member. Alpha Chapter, University of Louisville School of Medicine. 1997 Phi Delta Epsilon. Honor medical society. Lifetime member. 1994 Basolo-Oesper Award. Northwestern University Department of Chemistry. Awarded in recognition of departmental citizenship. 1993 Great Lakes Cluster Pew Research Fellow. Summer research fellowship in chemistry awarded by the Pew Research Foundation.

RESEARCH______2006- 2007 Principal Investigator. Microbiological study of the effects of porous Tantalum on human bone, with a focus on the osteoporotic female. 2006 Foot & Ankle Research Michael Aronow, MD. Anatomic description of the FHB insertion onto the hallucal proximal phalanx and biomechanical study of serial proximal phalangeal bone resection on FHB insertional integrity. 2001-2006 Orthopaedic Residency Research Dr. Gloria Gronowics, Ph.D. In vitro analysis of the effects of engineered silk on human osteoblast adhesion, proliferations, and mineralization. We are also elucidating the intracellular signaling pathway responsible for these cell responses. 2003-2004 Pediatric Orthopaedic Research - CCMC Dr. Brian Smith, M.D. Elucidation of the association of BMI and degree of curve correction in children undergoing scoliosis surgery with the development of Superior Mesenteric Artery Syndrome post-operatively. 2000 Medical Student Research in Orthopaedics Dr. Ed Tillett, M.D., Department of Orthopaedics, University of Louisville School of Medicine. Simulated arthroscopic conditions of the shoulder and fluoroscopically evaluated the relative position of the axillary nerve to the inferior margin of the joint capsule through a range of arm motions. June-Aug 1998 Summer Research Fellow Dr. Susan Galandiuk, M.D., Price Institute of Surgical Research, University of Louisville School of Medicine. Worked on identifying a microsatellite marker around the MSH2 gene associated with Dysplastic Ulcerative Colitis. 1995-1997 Graduate Student Kevin Jarrell, Ph.D., Department of Pharmacology, Boston University School of Medicine. Engineered a ribozyme consisting of a group II intron to generate a circular human exon by the process of inverse splicing. 1994-1995 Research Associate Procter & Gamble Company, Corporate Research Division. Worked on organic synthesis of a novel anti-arthritic drug, and a prodrug technology to enhance bioavailability. 1992-1994 Independent Research J. B. Lambert, Ph.D., Claire-Hamilton-Hall Professor of Chemistry, Northwestern University. Made use of a specialized NMR sequence to find structural evidence for hyperconjugation- or the sharing of p and s orbital electron density- in the neutral ground state of compounds.

PUBLICATIONS______1) Hakim-Zargar, M; Aronow, MS; Gibson, L; Obopilwe, Elifho. “Implications for the Anatomy of the Flexor Hallucis Brevis Insertion.” Foot Ankle Int. 2010 Jan; 31(1):65-8. 2) Smith, BG; Hakim-Zargar, M; Thomson, JD. “Low body mass index: a risk factor for superior mesenteric artery syndrome in adolescents undergoing spinal fusion for scoliosis.” J Spinal Disord Tech. 2009 Apr;22(2):144-8. 3) Hakim-Zargar, M.; Sagomonyants, K; Jhaveri, A,; Aronow, MS; Gronowicz, G. “Porous Tantalum Stimulates Osteogenesis in Osteoblast Cultures from Elderly Patients.” Orthopaedic Research Society Meeting: 2009 Poster Presentation. 4) Aronow, MS; Hakim-Zargar, M. “Management of rheumatoid disease in hindfoot arthritis.” Foot Ankle Clin. 2007 Sept;12(3):455-74 5) Hakim-Zargar, M; Rincon, L; Obopilwe, E; Aronow, M. “Anatomy of the Flexor Hallucis Brevis (FHB) Insertion: Implications for First MTP Joint Tissue Interposition and Implant Arthroplasty.” AOFAS Summer Meeting: 2007 Electronic Poster Presentation. 6) Hakim-Zargar, M; Chaudhry, J; Jhaveri, A; Karageorgiou, V; Kaplan, D; Gronowicz, G. “In vitro analysis of the effects of engineered silk on human osteoblast proliferation, mineralization, and integrins.”Orthopaedic Research Society Meeting: 2006 Podium Presentation. 7) Hakim-Zargar, M; Smith, B. “Body Mass Index- Risk factor for superior mesenteric artery syndrome in adolescents undergoing scoliosis surgery.” SRS, 2005 Podium Presentation. 8) Hunt, L.E., Eichenberger M. R., Petras R. E., Farmer M., Hakim-Zargar M., Galandiuk, S. “A microsatellite marker for dysplastic ulcerative colitis associated with human MSH2 gene.” American Association of Cancer Research: Philadelphia April, 1999 Abstract. 9) M. Hakim-Zargar. "Use of an Engineered Ribozyme to Produce a Circular Human Exon. Circular Exons: a Review." Thesis submitted in partial fulfillment of the requirements for the degree of Master of Arts. Boston University School of Medicine, 1997. 10) S. Mikheeva, M. Hakim-Zargar, D. Carlson and K. Jarrell. "Use of an engineered ribozyme to produce a circular human exon." Nucleic Acids Research. 1997 December, 15. 25(24):5085-94. 11) S. Saha, M. Hakim-Zargar, H. Zhou, M. Ptachne and K. Jarrell. "Selection of RNA molecules that activate transcription in yeast." RNA Processing Meeting: 1997 Abstract. 12) S. Mikheeva,M. Hakim-Zargar, D. Carlson and K. Jarrell. "Use of an engineered ribozyme to produce a circular human exon." RNA Processing Meeting: 1997 Abstract.