In collaboration with

Funded by

Cordially invites you to a lecture series on March 29-30, 2017 at the Institute of Auditorium University of the Philippines Diliman

March 29, 2017 1:30pm “ and infectious diseases” by Joseph DeRisi, Professor and Chair of the Department of and , University of California San Francisco, Co-President Chan Zuckerberg Biohub

March 30, 2017 2:30 pm “Therapeutic development for ” by Joseph DeRisi “Identification of the molecular target of the anti-malarial MMV08138” by Wesley Wu, Postdoctoral Fellow, University of California San Francisco

Dr. Joseph DeRisi is recognized as an early pioneer in functional genomics. During his graduate career at in the laboratory of Dr. Patrick O. Brown, he developed much of the automation, software, and methodology for producing DNA microarrays. In 1997, he was the first to produce and publish experiments using a DNA microarray representing an entire eukaryotic genome (Saccharomyces cerevisiae). Dr. DeRisi has since exploited genomic technology for the study of infectious disease, including malaria and viruses. His lab was the first to provide a high-resolution map for the blood stage transcriptome for and during the same year, his lab deployed a viral discovery array to assist with the identification of the SARS coronavirus during the global outbreak. His interests and pursuits continue to be diverse, yet focused on issues related to infectious disease, technology development and education. Recently, Dr. DeRisi’s lab has specialized in the use of ultra-deep sequencing technologies, sample preparation methodologies and bioinformatics to identify viral pathogens in both human and veterinary medicine. Dr. DeRisi is also dedicated to improvements in graduate education, including the establishment of an innovative interdisciplinary first quarter project-lab course that joins three graduate programs, Chemistry and Chemical Biology, Biophysics, and Bioinformatics.

Dr. Wesley Wu is a postdoctoral researcher in the laboratory of Joseph

DeRisi working on compound screening, resistance acquisition and biochemical analysis in Plasmodium falciparum, the causative agent of the most deadly form of malaria. He has previously used whole genome sequencing to identify novel drug targets in the parasite. He obtained his doctoral degree from the University of California Berkeley under the guidance of Dr. Matthew B. Francis.