CLK2 Antibody Cat. No.: 23-254
CLK2 Antibody
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 239-498 IMMUNOGEN: of human CLK2 (NP_003984.2).
TESTED APPLICATIONS: WB
APPLICATIONS: WB: ,1:500 - 1:2000
POSITIVE CONTROL: 1) BT-474
2) HeLa
3) Mouse brain
4) Mouse lung
PREDICTED MOLECULAR Observed: 70kDa WEIGHT:
Properties
PURIFICATION: Affinity purification
CLONALITY: Polyclonal
October 2, 2021 1 https://www.prosci-inc.com/clk2-antibody-23-254.html ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.
Additional Info
OFFICIAL SYMBOL: CLK2
ALTERNATE NAMES: Dual specificity protein kinase CLK2, CDC-like kinase 2, CLK2
GENE ID: 1196
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine- rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the BACKGROUND: PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.
ANTIBODIES FOR RESEARCH USE ONLY.
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October 2, 2021 2 https://www.prosci-inc.com/clk2-antibody-23-254.html