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A Y e 2 011 2011 Calendar Power PinkThird-Party Events Help Raise Critical Funds for Cancer Care and Research

The Plymouth Whalers hockey team Nick Karmanos, vice president of Development demonstrated the power of positive pinking last at Karmanos, was at the game to accept the October, as they donned custom pink uniforms Whalers’ donation. and dyed their hair pink to raise funds for the third “Third-party events like the Pink Out! are incred- annual Pink Out! for Awareness ibly important to the Karmanos Cancer Institute,” game. The Whalers, owned by Peter Karmanos, Jr., Karmanos says. “They raise critical funds in support raised about $18,000 for breast cancer research at of our mission to offer the best possible care for the Karmanos Cancer Institute. They also defeated our patients and provide critical funding for our the Windsor Spitfires 4-1, making the game all nationally-recognized cancer research efforts. This the more thrilling. would not be possible without the help of the The unique event, which took place October 16, many caring individuals who organize these terrific 2010 at Compuware Arena in Plymouth, featured events on our behalf and generate hundreds of breast cancer survivors dropping the puck at center thousands of dollars in support of our efforts.” ice during the ceremonial face off. The Whalers If your organization is interested in partnering with auctioned off the pink jerseys during and after the the Karmanos Cancer Institute, call game. Many of the 3,127 fans who attended also 313-576-8121. wore pink to show their support. The 2011 Pink Out! promises to be just as exciting. PHOTO: Dominique King www.midwestguest.com

January The Live Like Andi Run for a Cure SKIN: A Melanoma Research Benefit Connecting the Dots of Michigan’s 3rd Annual Hard Rock Café Detroit Pinktober 2011 Motor City Open: North Brothers Ford/City of “The More You Show, The More You Know” BCCCP Faith of a Mustard Seed Fundraiser The 8th Annual Kay McDevitt The Professional Squash Association Westland 5K Run/Walk Three Shots Against Cancer Florine Mark’s ReMARKable Women Memorial Golf Outing Shen Yun Performing Arts Live Luncheon Kroger Breast Cancer Promotion June Macy’s Twelve Oaks Breast Cancer August 8th Annual GFLCF Lung Cancer 5k Run/Walk February 11th Annual Kenneth J. Scott Awareness Fundraiser 21st Annual Hank Greenberg 3rd Annual Al Knake Golf Outing BMD Charities 21st Annual Charity Ball Memorial Golf Outing Plymouth Whalers 4th Annual Pink Out! Memorial Golf Invitational for Pancreatic Research Knit Michigan 8th Annual Kicks for the Cure Sista Strut John M. Malone Jr. MD, Second BAPS Charities Walkathon Leon and Lulu’s Pink with a Passion April Annual Golf Classic The 9th Annual Janet Lynn Ripper Golf Outing November 9th Annual Solstice Run Polly’s Walk for Hope 9th Annual Garden City Moose PCGC Golf Classic 11th Annual Celebration of Hope Lodge Cancer Auction The Third Annual Ryan O’Donnell Golf Classic hosted by Shaggieink July October 7th Annual Tammy Z Golf Outing Sky Foundation Inc. Fundraiser May 5th Annual Skating 4 the Cure Canton’s Tournament of Hope 7th Annual Image Salon Cut-a-thon The $500,000 Odyssey 2-Ball Putt Challenge All events open to the public. Cruising for the Cure September presented by Carl’s Golfland Better Made Breast Cancer Promotion Inclusive as of November 19, 2010. FDJ International Dragon Boats Festival Buddy’s Pizza Breast Cancer Promotion Equestrian Dreams Trail Ride 7th Annual Janice McTigue Golf Tournament For more details and a full list of events, Detroit Free Press Marathon 3rd Annual Ken Wood Memorial Golf Outing Hour Detroit’s Best of Detroit Party American Sewing Expo visit www.karmanos.org/events.asp JanuaryS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

February January is Cervical Cancer Screening Awareness Month. 1 2 3 4 20115 To learn more about cervical cancer treatment or 6 7 8 9 10 11 12 prevention, please visit Karmanos.org. 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 1 New Year’s Day

Orthodox 2 3 4 5 6 Armenian Christmas 7 Christmas Day 8

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Martin Luther 16 17 King, Jr. Day 18 19 20 21 22 23 24

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Karmanos.org 1-800-Karmanos For four consecutive years, the Karmanos Cancer • All of the Karmanos cancer specialists treat a specific “Karmanos is totally focused on cancer treatment, Center has topped the list of preferred hospitals in type of cancer. research and education,” says Karmanos President and southeast Michigan for cancer care, according to a • Best Doctors and Hour Detroit magazine recently CEO Gerold Bepler, M.D., Ph.D. “Cancer patients survey by the National Research Corporation. Here are singled out many Karmanos physicians and placed should know that we are deeply committed to providing a few reasons why our patients choose Karmanos over them on their “Best Doctors” and “Top Docs” lists. them with the highest quality care. Our cancer experts are other hospitals: • Karmanos offers access to more than 100 cancer discovering new therapies every day, which will one day treatments that no other local hospital has. lead to the end of this disease.” • Karmanos is one of only 40 National Cancer Institute- designated comprehensive cancer centers in the entire • There are more than 200 types of cancer and Karmanos For more information on cancer care and services call United States. not only treats them all – cancer is all we treat. 1-800-KARMANOS or 1-800-527-6266; or visit Karmanos.org. FebruaryS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

March 1 2 3 4 5 2011 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 1 2 Groundhog Day 3 4 5

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Prophet Muhammad’s 13 14 Valentine’s Day 15 16 Birthday 17 18 19

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February is National Cancer Prevention Month. Adopt a healthy lifestyle and follow a diet that contains more nutrient-rich foods, such as vegetables, grains and fruit. Exercise daily and undergo routine health screenings. Be sure and tell your doctor 27 28 if you have a family history of cancer.

Karmanos.org 1-800-Karmanos Living Proof the Value of a Colonoscopy

In June 2006, Judge Kevin Robbins support when I felt apprehensive. My mom and received a phone call that changed his life. I went to Karmanos for treatments together.” The caller was Rafael Prevot, a close friend Robbins’ cancer was spreading quickly. After who lived in New York City. undergoing surgery, Robbins began an aggressive “Rafael told me he had stage IV colon cancer six-month regimen, followed by and it had metastasized,” says Robbins, who is regular surveillance. Two years later, Robbins became cancer-free. He continues to see Dr. on the bench at Detroit’s 36th District Court Philip for checkups. and is a visiting judge for the Wayne County Circuit Court Criminal Division. “Rafael asked “A colonoscopy is the best way to see if a me to promise that I would get a colonoscopy, colorectal problem is caused by underlying and I told him I would. He died in 2008 at age cancer,” Dr. Philip says. “We think colonoscopies 49. He was just five days younger than me.” will reduce the number of new cases and people dying from the disease. The average age for an Robbins remained true to his word and got the initial colonoscopy is 50, but you may want to test. He also received an unexpected result: a get the test earlier if you have a family history stage III cancer diagnosis. of colon cancer, or some other related cancer or “I was completely shocked,” Robbins says. “I was bowel condition. The rate of colon cancer inci- dence and colonic polyps are higher in younger just 47 and had absolutely no symptoms. I had African Americans, and they should consider recently been married and had a newborn son. My getting the initial colonoscopy before age 50, late mother was also being treated for esophageal preferably starting at age of 45.” cancer and I was helping to care for her. Suddenly, I was also diagnosed with cancer.” Robbins remains thankful he got the test before turning 50, and urges family, friends and Robbins chose to be treated at the Karmanos colleagues to do the same. Cancer Center, the same hospital where his mother received care. He also chose the same “Rafael was my guardian angel,” says Robbins, physician: Philip Philip, M.D, Ph.D., F.R.C.P., who now has three children. “He could have a member of the Gastrointestinal Oncology crawled into a shell and kept his diagnosis to Multidisciplinary Team and professor of himself. Instead, he urged his family and friends to get a colonoscopy. And I’m forever grateful, Medicine and Oncology at Karmanos and because I’d be dead if I didn’t get that test right School of Medicine. away. It’s all about early diagnosis and treatment “I was so happy with the care my mom received – I’ll never stop spreading that message.” from Dr. Philip, I knew that I wanted him to For more information, call 1-800-KARMANOS Judge Kevin Robbins treat me,” Robbins says. “He gave me a lot of or 1-800-527-6266. MarchS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

April 1 2 3 4 5 6 7 8 9 2011 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 1 2 3 4 5

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Daylight Saving 13 Time Begins 14 15 16 17 St. Patrick’s Day 18 19

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March is National Colorectal Cancer Awareness Month. To learn more about colorectal cancer treatment or prevention, please visit Karmanos.org. 27 28 29 30 31

Karmanos.org 1-800-Karmanos The Habit Karmanos Helps Lung Cancer Patient Breaking Quit Smoking – For Good

Bonnie Evans admits she grew up in Hardy told Evans about the smoking a strict household. But there’s one thing cessation workshops at Karmanos, her parents allowed their children to do, organized by the department of Patient starting in their late teens. and Community Education. “They gave us permission to smoke,” says “The process of quitting is different for every Evans, 55. “I started smoking at age 17.” patient – that’s why we help patients create a personalized smoking cessation plan,” Hardy By the time Evans became an adult, she says. “Very few people are able to quit cold went from smoking a few occasional turkey. Relapse is often part of recovery for cigarettes to two packs a day. Smoking any addiction.” helped her cope with stress, she said. Evans made greater progress once she began Life became more stressful for Evans in attending the workshops, available at no charge 2003 when doctors diagnosed her with to Karmanos patients and the community. stage IV lung cancer. After three months of chemotherapy and , the Finally, after trying for five years, Evans tumors were gone. Still, Evans continued to quit smoking for good in January 2010. smoke. Six months later, the cancer returned. “It took a whole team of people to help me “I felt completely ashamed, and my quit.” says Evans. “At Karmanos, there is no doctor made me feel even more ashamed,” condescending attitude. Instead, I heard, Evans says. “I wanted to quit and tried ‘We’re going to fight this together.’” many times, but nothing worked.” After quitting, Evans discovered new inter- Evans switched doctors and came to ests. She participates in women’s wellness and Karmanos, where she began treatment under scrapbooking groups at Karmanos. She also the care of Shirish Gadgeel, M.D., leader, participates in art therapy and makes birthday Thoracic Oncology Multidisciplinary and get-well cards for Karmanos patients. Team, and associate professor, Wayne State “I’d be in a much darker place had I not University School of Medicine. She also gone to Karmanos,” Evans says. Today, I’m a made an appointment with Oncology happy, vibrant and independent person. I’ve Social Worker Kathleen Hardy. been given another chance, and I’m going to “At Karmanos, we provide the tools to help live life to the fullest.” them quit,” Hardy says. “And the desire to For more information, call 1-800-KARMANOS quit has to come from the patient – Bonnie Evans or 1-800-527-6266. we don’t force anyone into it.” AprilS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

May Karmanos provides world class treatment close 1 2 3 4 5 6 7 2011 to home with full service outpatient facilities in 8 9 10 11 12 13 14 15 16 17 18 19 20 21 Farmington Hills, Rochester Hills and Detroit. 22 23 24 25 26 27 28 29 30 31 1 2

3 4 5 6 7 World Health Day 8 9

National 10 Volunteer Week 11 12 13 14 15 16

National Minority Cancer 17 Awareness Week 18 19 Passover 20 21 22 Good Friday 23

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Karmanos.org 1-800-Karmanos Destroying

RacialUnprecedented Disparities Partnership aims to save lives

African Americans have the highest death program leader, Population Studies and Disparities rate and the shortest survival rate of any racial and Research; and professor and associate director, ethnic group in the United States for most cancers, Department of Oncology, WSU School of according to the American Cancer Society. Medicine, is a co-principal investigator for SEMPAC. Since 2005, Dr. Albrecht and her team To save lives and close the gap on racial disparities at Karmanos have engaged several community related to cancer care in southeast Michigan, the partners to create and participate in the Detroit Karmanos Cancer Institute has teamed with the Community Network Program (CNP), which Josephine Ford Cancer Center at Henry Ford received a $2.5million grant over five years from Health System and Wayne State University School the NCI. of Medicine to create the Southeast Michigan Partners Against Cancer (SEMPAC). The Detroit CNP supported community-based education, training and research collaboration The National Cancer Institute (NCI) helped to address the health disparities of older African make this project possible with a more than Americans in the city of Detroit. SEMPAC is an $4-million, five-year grant. SEMPAC is one of outgrowth of the CNP partnership, covering the 23 NCI-supported projects in the nation, and tri-county area. one of six dedicated to addressing cancer health disparities among African Americans. SEMPAC “No one institution alone can restore the health is also the only NCI-funded project committed of our community and region,” Dr. Albrecht says. to improving access to cancer screenings and “We need everyone’s support. We can and will treatment for older, underserved African make an impact on cancer disparities. Americans in an urban area. SEMPAC will create regional partnerships that “There are many in our community who are not will build awareness and educate residents about aware of the services available to them, may not cancer treatment options; provide tools to help understand how to access services, and therefore residents make better health care decisions don’t have the greatest chance of survival – this related to cancer care; and increase the under- is unacceptable,” says Karmanos President and standing of the importance of biospecimens CEO Gerold Bepler, M.D., Ph.D. “As cancer to advance cancer research. physicians and researchers, our focus is to find “We have a real problem right under our noses the best treatment options and cures to save and we need to do something about it,” says lives. This partnership will magnify our outreach Robert Chapman, M.D., director of the Josephine and help save the lives of some of our most Ford Cancer Center, Henry Ford Health System vulnerable citizens.” and SEMPAC co-principal investigator. “Detroit Terrance Albrecht, Ph.D., associate center and southeast Michigan’s ability to create partnerships will be the envy of the nation.” Terrance Albrecht, ph.d. director for Population Sciences at Karmanos; Robert chapman, m.d. MayS u nday M onday T u esday W ednesday T h u rsday F riday 2011S at u rday

1 2 3 4 5 Cinco de Mayo 6 7

Oral, Head & Neck Cancer Awareness Week 8 Mother’s Day 9 10 11 12 13 14

Komen Detroit 15 16 17 18 19 20 21 Race for the Cure®

Victoria Day 22 23 (Canada) 24 25 26 27 28

June May is Skin Cancer Detection 1 2 3 4 and Prevention Month. To 5 6 7 8 9 10 11 learn more about skin cancer 12 13 14 15 16 17 18 treatment or prevention, please 19 20 21 22 23 24 25 visit Karmanos.org. 26 27 28 29 30 29 30 Memorial Day 31

Karmanos.org 1-800-Karmanos Taking Patients to another place Photographs Create a Soothing Hospital Atmosphere

Patients and visitors have a different hospital experience when they enter the 9th floor Inpatient Unit at the Karmanos Cancer Center. At first glance, you might almost think you’ve entered an art gallery.

More than 100 peaceful and highly-artistic photographs of Michigan scenery line the halls and patient rooms – and Karmanos employees shot all the images. PHOTO: Brad Ciecko The professionally matted and framed photos depict an array of scenes, from Comerica Park and the Detroit River “We began displaying the photos in early 2009, and the Oncology Care Associate Brad Ciecko is one of the skyline, to Mackinac Island and Tahquamenon Falls in patients and staff absolutely love them,” Fred says. “The featured photographers. Among his standout images the Upper Peninsula. The collection also features photos photos help take patients away to another place. I once is the Pointe Aux Barques Lighthouse, located on of flowers, butterflies and birds, as well as polar bears and noticed a patient and his wife who were admiring a photo Lake Huron near Port Hope. peacocks at the Detroit Zoo. of a lighthouse. They told me they were from the other side “That photo is a personal favorite,” says Ciecko, a self- of the state and recognized the scene. He said it made him “We initiated the photo project because we wanted to make taught photographer who is refining his skills through feel as if he were home.” the floor more warm and inviting for inpatients,” says online courses offered by the Academy of Art University Valerie Fred, operations support specialist at Karmanos. Robin Stone is a former Patient and Advisory Council in San Francisco. “It’s great to bring that expressive part “Many of our staff members are talented photographers, so committee chair. She is also being treated at Karmanos of my personality to my job. The patients connect with me we asked employees to submit photos for consideration.” for ovarian cancer. Two years ago, she experienced the through the photos, and it makes me happy to know the power of the photographs first-hand as an inpatient. photos help take their minds off cancer.” The Patient and Family Advisory Council, an advocacy group that represents the needs of cancer patients and their “While I was recovering from surgery, I often looked at For more information about cancer services, call families, reviewed more than 200 submissions and made the photos while I walked the halls for exercise,” Stone 1-800-Karmanos or 1-800-527-6266, or visit Karmanos.org. final selections. The council is made up of current and says. “The photos are simply breathtaking. They provide former Karmanos patients and their family members. something of beauty to patients who are fighting cancer. Fred is the council’s facilitator. Their soothing qualities help in the recovery process.” JuneS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

As Michigan’s only hospital dedicated exclusively to 2011 beating cancer, Karmanos dedicates entire teams of experts to each patient. 1 2 3 4

National Cancer 5 Survivors Day 6 7 8 Shavuot 9 10 11

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Karmanos.org 1-800-Karmanos Red-Hot Rowers Karmanos Dragon Boat Team Raises Critical Funds for Breast Cancer Research

The Karmanos Life Preservers Dragon breast cancer. Karmanos receives Boat Team symbolizes the cooperative between $10,000 and $12,000 of spirit staff members embrace in providing those monies each year. the very best care to all Karmanos Cancer The Karmanos team will compete Center patients. once again this month in the Dragon boating, a popular early summer International Dragon Boat activity in the Orient, typically includes a Festival, July 8-10 at Waterfront dragon-shaped boat with 20 paddlers, a Park in Tecumseh. The high-spirited helmsman on one end and a drummer facing event attracts thousands of people to paddlers on the other end to keep the team the shores of Lake St. Clair at the motivated. Team members say the drummer mouth of the Detroit River. About keeps them in sync, allowing them to row faster. 115 teams and paddlers from all over the world enter With team members from various Karmanos the festival. departments, these paddlers support patients during their work hours and then use their Dedicated Karmanos team free time to raise funds for breast cancer members include Barbara Adam, PHOTOS: Bert Cozens research. The team also includes breast cancer nurse practitioner; Mara Jelich, survivors who take part in rowing activities director of Radiation Oncology; Karmanos, originally spearheaded the effort to to combat lymphedema, a common side effect team Captain Laura Mantha, get people involved in the dragon boat team. of breast cancer treatment. research nurse in Population “As dragon boaters, we continue to share Studies; Lynne Moseley, D.D.S., our laughter with others; to support each Since Karmanos became an official beneficiary director of Oral Oncology at honors in the “Hospital Challenge” at last other through the thrill of competition; and of the International Dragon Boat Festival and Karmanos; Lee Sippel, staff nurse year’s International Dragon Boats Festival to honor those we have lost,” she says. “We the Life Preservers took to the waters six years in Karmanos’ Breast Center; and Adrice for the Cure. spread the message that men and women can ago, $50,000 has been raised for breast cancer Wiper, educator in the Department of Patient research at Karmanos. Members of the Life lead full and active lives after treatment for and Community Education. “We’re thrilled to be recognized for doing Preservers team commit to raising at least $250 breast cancer, through public awareness and what we love -- helping our patients in all from year to year and always seek fun ways to Life Preservers members say they love the paddling our best.” ways possible, not only in the clinic but also camaraderie, not to mention the great workout raise more funds. Monies raised are placed in a by funding research that promises them a To learn more about joining the Life Preservers and the sense of working as a team. The team fund administered by the International Dragon brighter future,” Dr. Moseley says. Dragon Boat team, contact Laura Mantha at Boat Festival for the Cure. Over the past seven is so good at what they do, in fact, that they (313) 576-8401 or [email protected] years, the festival has raised more than $1.3 received a Heroes of Breast Cancer award for Helen Dries, a retired nurse from Karmanos million for hospitals that research and treat Philanthropy in 2010, as well as taking top and breast cancer survivor who was treated at JulyS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

August July is Sarcoma Awareness Month. To 1 2 3 4 5 6 2011 learn more about sarcoma treatment or 7 8 9 10 11 12 13 14 15 16 17 18 19 20 prevention, please visit Karmanos.org. 21 22 23 24 25 26 27 28 29 30 31 1 Canada Day 2

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Karmanos.org 1-800-Karmanos Up Close: Philip A. Philip, M.D., Ph.D., F.R.C.P. In Search of Great Challenges As the eldest child in his household, Philip discovered the challenges of oncology while Agop Philip, M.D, Ph.D., F.R.C.P., entered the studying clinical pharmacology at the family trade when his father died. At age 11, he University of London. began spending the hot Iraqi summers working “I realized that science would be very instrumental in the family’s shoe factory. in driving oncology while offering lots of “I quickly learned that the factory was not the opportunities for discovery,” Dr. Philip says. “I place for me,” Dr. Philip says. “The government became excited by the prospect of applying began placing more restrictions on private science to patient care.” businesses. I wanted to become a professional in Dr. Philip says he focused his interests on a different field – to find something demanding gastrointestinal oncology because it was receiving but with fewer outside restraints.” relatively little research attention compared to Stirred by his growing intellectual curiosity, other types of cancer. To further his research aspirations, Dr. Philip came to the U.S. in the Dr. Philip set off on the path of challenge early 1990s and joined Karmanos in 1995. In and discovery, which led him to a rewarding addition to being leader of Karmanos’ Gastroin- career in medicine. Oncology continually testinal Multidisciplinary Team, Dr. Philip is also inspires him to search for improved therapies president of the Medical Staff at Karmanos. for cancer patients. “Karmanos is a tremendous working Dr. Philip embarked on his journey in the mid environment,” Dr. Philip says. “I’ve always 1960s when he entered the American Jesuit been impressed by the quality of our clinicians Fathers’ College in Baghdad. He showed an and their dedication to fighting cancer. Our PHILIP A. PHILIP, M.D., Ph.D., F.R.C.P. aptitude for science and mathematics and ] interests are completely aligned with offering considered becoming an electronic engineer. TITLE: Leader, Gastrointestinal Multidisciplinary Team compassionate patient care and discovering Instead, he followed his friends and applied Professor of Medicine and Oncology. new cancer treatments. O for medical school. BOARD CERTIFIED: Internal medicine and medical oncology. “I’m very fortunate to have developed my career “It’s a decision I never regretted,” Dr. Philip EDUCATION: B.A., American Jesuit Fathers’ College, Baghdad. M.D., to the point where I’m practicing in a highly says. “I enjoy combining medicine and research University of Baghdad College of Medicine; Ph.D. in Clinical Pharmacology advanced health care system, contributing to and Pharmacogenetics, University of London, Guy’s Hospital Medical School. to practice high-quality patient care.” patient care and participating in the research [BI process that will help advance cancer care FAMILY: Wife Viva and daughters Carolyn, 17, and Celene, 10. Dr. Philip left Iraq in the early 1980s to complete his doctorate in England. He globally. The greatest opportunities lie ahead.” HOBBIES: Traveling. “My favorite places are London, Paris and all of Italy.” AugustS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday September 1 2 3 4 5 6 7 8 9 10 2011 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 1 Ramadan Begins 2 3 4 5 6

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Karmanos oncologists specialize in treating a specific type of cancer and are on the faculty of Wayne State University School of Medicine. Eid-al-Fitr 28 29 30 (End of Ramadan) 31

Karmanos.org 1-800-Karmanos Problem-Solving Patient Prostate Cancer Survivor Praises Cryotherapy as a Treatment Option

Al Terwilliger

Al Terwilliger, 71, of Clawson, has been a problem “I read a lot about Dr. Cher and how well-known he is,” procedure involves only needles, recovery is very quick and solver all his life. Terwilliger says. “I made an appointment with him to go there is no scarring. Karmanos is one of the leaders in using over my treatment options. He told me the pros and cons cryotherapy for prostate cancer and other tumors.” So when the results of his prostate-specific antigen (PSA) about robotic surgery, radiation and cryotherapy. I opted for Dr. Cher adds that with cryotherapy, men can have blood test were elevated last August, he dealt with the the latter, since my prostate cancer was in an early stage and customized treatment depending on where the cancer occurs problem directly, rather than wait to see what might happen. confined to one small area of the prostate. Two hours after in the prostate. If cancer cells are located in only a small area, undergoing cryotherapy in September, I was going home.” “It was not unlike how I approach business,” Terwilliger the freezing process can be applied to that area, eliminating says. “The first thing I did was go on the Internet.” Cryotherapy is performed with a series of needles that target potential side effects related to bladder function or sexual Terwilliger is chairman of Protecto Horse Equipment, which regions of the prostate. Once inserted, the needles freeze the function. tissue, killing any cancer cells in the area. The procedure is sells products that protects harness racers and their horses. Today, Terwilliger is cancer free and says he feels like he’s performed under general anesthesia and typically takes about Terwilliger invented many of the company’s products, which “30 or 40 years old.” are marketed worldwide. two hours. Recovery time for Terwilliger was less than a week. “I would definitely recommend cryotherapy to other men “Cryotherapy can be used for the whole prostate or just part “Everyone who knows me says I’m the most creative person with prostate cancer,” he says. “It was the smartest move I’ve of it,” says Dr. Cher, who has performed about 300 cryothera- they know,” he says. “I solve problems. I’m a better doer than ever made. I found a great solution for my medical problem.” a thinker.” py procedures. “It’s great for men wanting to avoid surgery or radiation. Studies suggest that it may be just as effective. To learn more about prostate cancer screening and diagnosis or In his online research, Terwilliger kept coming across to make an appointment, call 1-800-KARMANOS or the name of Michael L. Cher, M.D. Dr. Cher is chief of “This is an image-guided treatment and it’s pretty specialized. 1-800-527-6266. Urology at the Barbara Ann Karmanos Cancer Center and Since there is no incision, the surgeon has to be very comfort- chairman of the Department of Urology at Wayne State able with using ultrasound to guide the needles to their proper University School of Medicine. locations. The idea is to be as precise as possible. Since the SeptemberS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

September is National Prostate, Ovarian, Gynecologic, and Leukemia and Lymphoma Cancer Awareness Month. 2011 To learn more about treatment or prevention of these types of cancer, please visit Karmanos.org. 1 2 3

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Karmanos.org • 1-800-Karmanos Forging

Karmanos Scientists DevelopExciting Potential New Paths Treatment for Aggressive Tumors

Traditionally, most cancer therapies involve “Triple-negative breast cancer is generally more some combination of chemotherapy, radiation active and aggressive than other types of breast therapy and surgery. But what if doctors were to cancer,” Dr. Nahleh says. “Through this study, we’re supplement these therapies by helping the body’s hoping to improve complete tumor response by immune system detect tumors and destroy them? combining chemotherapy with immunotherapy.”

That’s the exciting new direction scientists at the Immunotherapy works through the patient’s Karmanos Cancer Institute are taking toward a T cells, which are part of our immune system. potentially ground-breaking treatment for cancer Scientists draw blood from the patient, stimulate called targeted T cell immunotherapy. Karmanos the T cells, and arm the T cells with bispecific is currently conducting a clinical study applying , which programs them to find and immunotherapy to women with one of the deadli- destroy tumor cells. Once the T cells are infused est forms of the disease – triple-negative breast into the patient after chemotherapy, they destroy cancer. The research is unique to Karmanos and any remaining tumors and vaccinate the patient funded by a $3 million, five-year research grant against re-growth of their tumors. Lawrence by the National Institutes of Health (NIH). A Lum, M.D., DSc, professor of Oncology, total of 40 patients are involved in the study. Medicine, and Immunology and Microbiology at Karmanos and Wayne State University School “This grant from the NIH speaks to the truly of Medicine, is a pioneer in developing this type innovative research being conducted at of immunotherapy for cancer patients. Karmanos and establishes the Institute’s leadership role in creating care standards that “If we can double the number of women other hospitals will follow in the future,” whose cancer is completely eradicated through Zeina Nahleh, M.D. says Gerold Bepler, M.D., Ph.D., Karmanos immunotherapy, it would be a home run in Lawrence Lum, M.D., DSc president and chief executive officer. how we treat women with triple-negative breast cancer,” Dr. Lum says. Zeina Nahleh, M.D., associate professor of Medicine and Oncology at Karmanos and Wayne “Immunotherapy also has the potential to become a “Immunotherapy is a growing field within oncology and provides State University School of Medicine, and co-leader very powerful tool in fighting other types of tumors,” great hope for the future,” Dr. Nahleh says. “The only way we of the Breast Oncology Multidisciplinary Team Dr. Nahleh adds. “Based on data from earlier studies, can make advancements in the fight against cancer is to conduct at Karmanos, is the principal investigator on the these enhanced T cells may remain active within a clinical trials like this immunotherapy study. I’m proud to be part breast cancer immunotherapy study. patient for years.” of an organization like Karmanos that fosters this type of research.” OctoberS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

November October is National Breast Cancer Awareness 1 2 3 4 5 Month. To learn more about breast cancer treatment 2011 6 7 8 9 10 11 12 13 14 15 16 17 18 19 or prevention, please visit Karmanos.org. 20 21 22 23 24 25 26 27 28 29 30 1

2 3 4 5 6 7 8 Yom Kippur

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National 16 17 18 19 20 Simchat Torah 21Mammography Day 22 23 24

30 31 Halloween 25 26 27 28 29 Karmanos.org 1-800-Karmanos A New Perspective

Cancer Survivor Generoonusly Supports L ife Karmanos Leukemia Specialists

In 2004, Darryl Staskowski of Shelby Karmanos and Wayne State University Township made an appointment with School of Medicine. his family doctor for what he thought was “Other hospitals didn’t give us a good a lingering cold. Instead, he wound up vibe, but from the moment we met with being rushed to the hospital with a far Dr. Zonder, we knew Karmanos would more serious problem. be the best place for treatment,” Stas- “I had a persistent cough and felt very kowski says. “He emanated a high level winded,” says Staskowski, 45, vice of confidence that gave me strength. ” president of Global Infrastructure at Staskowski’s treatment regimen was Kelly Services. “An X-ray showed a mass anything but easy, Dr. Zonder says. about the size of a fist near my heart.” “Darryl went through a two-year course Doctors diagnosed Staskowski with of chemotherapy, starting with an T Cell Acute Lymphoblastic Leukemia, intensive induction regimen, followed or ALL. Suddenly, he was faced with a by additional cycles of chemotherapy, life-threatening medical situation that and eventually prolonged maintenance required making quick decisions. therapy,” Dr. Zonder says. “He required Darryl Staskowski “You hear about people getting cancer, chemotherapy injections in his spinal cord but I never thought it would happen to and radiation to prevent the cancer from me – especially at age 39,” Staskowski spreading to his brain. Throughout this “This experience gave me a completely “We are deeply grateful to Mr. Staskowski says. “I thought, ‘Now what do I do?’” two-year obstacle course, Darryl was very different perspective on family, faith and for his gifts in support of cancer care,” says engaged and kept a positive attitude. He what’s really important in life,” Staskowski Nick Karmanos, vice president of Develop- Staskowski and his wife visited several never became defined by his illness and says. “I was taken right to the edge. At one ment at Karmanos. His generous support hospitals in search of the best cancer care, did everything he could to become well.” point, I was in intensive care. Now, I’m will help provide critical funding in our but only one met his needs: the Karmanos living a normal life. I also began making quest to find a cure for diseases such as Despite facing some serious complica- Cancer Center. The Staskowskis met with regular charitable contributions to ALL and other types of leukemia.” tions during the course of treatment, Jeffrey Zonder, M.D., a member of the Karmanos because I want to help leukemia Staskowski went into remission and is For more information on cancer screening Hematology - Malignant Multidisciplinary patients and have an impact on a place now cancer-free. He says he’s changed as and diagnosis or to make an appointment, call Team, and associate professor of Medicine that provided me with such great care.” and Oncology, Hematology/Oncology at a person after beating the disease. 1-800-KARMANOS or 1-800-527-6266. NovemberS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

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November is National Hospice Month and Pancreatic Cancer Awareness and Lung Cancer Awareness Month. To learn more, please visit Karmanos.org. Muharram/ 27 New Year 28 29 30

Karmanos.org 1-800-Karmanos SupportingAdvanced Science Clinical Trials Office Helps Physicians and Scientists Develop New Cancer Treatments

At the Barbara Ann Karmanos Cancer Institute, patients have access to more than 100 cancer-fighting treatments that can’t be found at any other local hospital. These advanced therapies are made possible in part by the Clinical Trials Office, a committed team of about 90 staff members who provide professional “behind-the-scenes” support. “Above all, our main objective is to ensure that patients are safe,” “As a NCI-designated comprehensive cancer center, “Our office provides three main functions,” says Helen Peck, Peck says. “Patients who choose to enroll in clinical trials are very Karmanos has a duty to perform cancer focused research – director of the Clinical Trials Office at Karmanos. “Our closely monitored for any adverse reaction, and patients can opt that’s why we offer such an extensive clinical trials program,” study coordinators screen patients and verify their eligibility out of a trial at any point.” Peck says. “Our goal is to offer every Karmanos patient the for trials, they register or enroll the patient onto the trial and opportunity to enroll in a . And approximately ensure the specific protocol (clinical trial) instructions and A new medication must be compared against standard thera- 25 percent of our patients are involved in a therapeutic requirements are followed. Our regulatory coordinators help pies and proven safe for patient use before it can receive Food clinical trial, which is much higher than the national average secure approvals from our internal review and institutional and Drug Administration approval and be made available as a of about 10 to 15 percent. review boards. And our research nurses primarily support standard therapy. the physicians and patients in the clinic. These nurses bridge “Clinical trials are the only way we can improve cancer Karmanos has one of only 14 National Cancer Institute (NCI)- the gap between the clinic and our office.” therapies and learn if a promising new drug is effective. funded Phase I clinical trials programs in the United States and The Clinical Trials Program is a great benefit for every patient Among other duties, the CTO meets internal and federal Canada, and the only such program in Michigan. Karmanos is who comes through our doors.” regulations by collecting and submitting data for all trials. also one of only 40 NCI-designated comprehensive cancer centers. For studies initiated by Karmanos researchers, the office’s At any one time, Karmanos conducts about 400 clinical trials For more information on clinical trials at Karmanos, call Quality Assurance and Data and Safety Monitoring extending across treatment and non-treatment protocols. In 2009, 1-800-KARMANOS or 1-800-527-6266, or visit Karmanos.org. committees provide close oversight. more than 5,500 Karmanos patients enrolled in a clinical trial. DecemberS u nday M onday T u esday W ednesday T h u rsday F riday S at u rday

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Karmanos.org 1-800-Karmanos Karmanos medical staff share stories about their First Jobs

David Gorski, M.D., Ph.D. Robert Morris, M.D. Breast Multidisciplinary Team Stephanie Mellon-Reppen, Gynecology Oncology Multidisciplinary Isaac Powell, M.D. Co-Leader and Breast Cancer RN, MSN, ACNP Team Leader and Professor of Genitourinary Oncology Biology Program Co-Leader Nurse Practitioner, Bone Marrow Gynecologic Oncology Multidisciplinary Team member Transplant and Cell Therapy Program and Professor of Urology

“At age 15, I began working at a Burger “My first real job, while attending high “I grew up in Maple Grove, Minn., at King in Livonia. Unfortunately, it was school, was working at Joe’s Italian Bakery the outermost rim of suburban sprawl “At age 13, I began selling the Chicago the closing shift, and Burger King didn’t in Livonia. I met wonderful people, pushing into farmland. As such, I had Defender newspaper door-to-door in close until 2 a.m. The manager also learned to cook and speak a little the choice of either washing dishes at Gary, Indiana. I did this for about two insisted that I work some weeknights, Italian, too! This was also my first real a chain restaurant or working on a years every Friday evening and Saturday and I had school. Desperate for my experience with customer service and local farm. Outside work appealed to morning. I thought I was a pretty own source of cash, I begged my parents catering people’s parties is a crash course me the most, so at age 15 I began successful salesman at the time, but to let me try it. They gave in, and I in customer service! After closing working on a neighbor’s farm. Although most of my sales were to relatives and did – for about three weeks. In the one night, some of the stockers were the passing years may lend itself to friends. Besides delivering on days end the price was too high. I stayed up throwing “pies” at each other – and who embellishment, for two summers I when it rained or snowed, the most past 2 a.m. two or three school nights hasn’t always wanted to throw a pie? I dug miles of fence post holes, pruned memorable part was being chased by a week, which was affecting my school picked one up from the display case and endless acres of Christmas trees, and dogs. I remember being aware of work. Because I didn’t have my driver’s threw it at a co-worker who ducked, baled and stacked mountains of hay. which homes in the neighborhood license yet, one of my parents had to sending a lemon meringue pie under the Even though I never used those skills kept dogs. At a young age, I learned pick me up. I learned pretty quickly oven. I found out they were throwing pie again, I loved the job and learned all a lot about the hardships of the that school came first.” plates filled only with whipped cream! about hard work.” working world.” Besides the wonderful friendships I made, the best part was having all the cannolis and pizza I could eat!” JanuaryS u nday M onday T u esday W ednesday T h u rsday F riday2012S at u rday

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February January is Cervical Cancer Screening 1 2 3 4 Awareness Month. Regular Pap tests can 5 6 7 8 9 10 11 12 13 14 15 16 17 18 help identify the disease in its early stages, 19 20 21 22 23 24 25 when cancer is the most treatable. 29 30 31 26 27 28 29

Karmanos.org 1-800-Karmanos NONPROFIT ORG WINTER 2011 • VOLUME 6 | NUMBER 3 U.S. POSTAGE ...... PAID EXECUTIVE STAFF DETROIT, MI PERMIT NO. 1579 Gerold bepler, m.d., Ph.D. President and Chief Executive Officer Karmanos.org Ann G. Schwartz, Ph.D., MPH Executive Vice President/Deputy Director 1-800-KARMANOS George Yoo, m.d., facs Mail Code: NCO6MC Chief Medical Officer 4100 JOHN R GARY MORRISON Chief Operating Officer DETROIT, MI 48201 Nick Karmanos Vice President, Development ...... Karmanos Cancer Institute Board of Directors

Alan S. Schwartz, Chair Allan Gilmour (ex officio) Randolph J. Agley, Vice Chair Adnan Hammad, Ph.D. Charles E. Becker, Lead Vice Chair Patricia Hartmann Richard M. Gabrys, Vice Chair David Jacob W. James Prowse, Vice Chair Eleanor M. Josaitis Jonathan S. Aaron Peter Karmanos, Jr. Eugene Applebaum C. Michael Kojaian Gerold Bepler, M.D., Ph.D. (ex officio) Edward C. Levy, Jr. Paul Borman Mary Matuja Armando R. Cavazos Timothy Monahan Daniel Cornwell Paul L. Nine KC Crain Thomas D. Ogden Stephen D’Arcy (ex officio) Valerie M. Parisi, M.D. (ex officio) Debbie Dingell Dick Purtan Joseph Dresner Hilary Ratner, Ph.D. David W. Drews Eunice Ring Michael E. Duggan Gary Sakwa Kenneth Eisenberg Nazli G. Sater Email: [email protected] ...... Lillian Erdeljan Marc R. Schechter Jay Farner Nettie H. Seabrooks ABOUT Karmanos Michael Ferrantino, Jr. Nedda N. Shayota The Barbara Ann Karmanos Cancer Institute is Nathan Forbes Robert A. Stone one of only 40 National Cancer Institute-designated Stanley Frankel David Trott comprehensive cancer centers in the United States. Myron Frasier Vainutis K. Vaitkevicius, M.D. Bruce A. Gershenson Nancy Yaw Federal designation as a comprehensive cancer center John A. Giampetroni is the pinnacle of translational oncology research. Thank you to outgoing members Fred Olson and Richard F. Roth Mary ANn SHort Vice President, Marketing and Communications Karmanos Cancer Center Board of Directors

Linda H. Remington Charles E. Becker, Chair Phillip A. Phillip, M.D., Ph.D. (ex officio) Editor Timothy Monahan, Vice Chair W. James Prowse Director, Marketing and Communications Gerold Bepler, M.D., Ph.D. (ex officio) Anthony J. Rusciano Leslie C. Bowman Alan S. Schwartz (ex officio) Associate Editors: Armando R. Cavazos Nettie H. Seabrooks Patricia A. Ellis Myron Frasier Maureen L. Stapleton Media Relations Manager Thomas A. Goss Jane R. Thomas, Ph.D. S. Scott Hunter Buzz Thomas Elizabeth Katz Denise Ilitch Manuel Valdivieso, M.D. External Marketing and Communications Associate Valerie M. Parisi, M.D. (ex officio) George Yoo, M.D. (ex officio) Christine Parker Thank you to outgoing memberKenneth Eisenberg Internal Marketing and Communications Associate (as of January 1, 2011) ...... Photos by Stephen Lengnick, Plum Street Studio Copyright 2010 Barbara Ann Karmanos Cancer Institute