Menopause & Hormones Common Questions

What is menopause? What is hormone therapy for menopause? Menopause is a normal, natural change in a woman’s Lower hormone levels in menopause may lead to hot life when her period stops. That’s why some people flashes, vaginal dryness, and thin bones. To help with call menopause “the change of life” or “the change.” these problems, women may be prescribed estrogen During menopause a woman’s body slowly produces or estrogen with progestin (another hormone). Like less of the hormones estrogen and progesterone. This all medicines, hormone therapy has benefits and often happens between ages 45 and 55. A woman has risks. Talk to your doctor, nurse, or pharmacist about reached menopause when she has not had a period for hormone therapy. If you decide to use hormone 12 months in a row. therapy, use it at the lowest dose that helps. Also use hormones for the shortest time that you need them. What are the symptoms of menopause? Who should not take hormone therapy for Every woman’s period will stop at menopause. Some menopause?Who should not take hormone therapy women may not have any other symptoms at all. As for menopause? you near menopause, you may have: WomenWomen who: who: • Changes in your period—time between periods or • • Think Think they they ar aree pregnant. pregnant. flow may be different. • • Have Have pr problemsoblems with with vaginal vaginal bleeding. bleeding. • Hot flashes (“hot flushes”)—getting warm in the • • Have Have had certain certain kinds kinds of ofcancers. cancers. face, neck, or chest, with and without sweating. • Have had a stroke or heart attack. • Have had a stroke or heart attack. • Night sweats that may lead to problems sleeping • Have had blood clots. and feeling tired, stressed, or tense. • Have had blood clots. • Have liver disease. • Vaginal changes—the vagina may become dry and • Have liver disease. thin, and sex may be painful. What are the benefits of using hormone • Thinning of your bones, which may lead to loss of therapy for menopause? height and bone breaks (osteoporosis). • Hormone therapy may help relieve hot flashes, Who needs treatment for symptoms of night sweats, vaginal dryness, or dyspareunia (pain menopause? with sexual activity). • For some women, many of these changes will go • Hormones may reduce your chances of getting away over time without treatment. thin, weak bones (osteoporosis), which break easily. • Some women will choose treatment for their What are the risks of using hormone symptoms and to prevent bone loss. If you choose therapy? hormone treatment, estrogen alone or estrogen with progestin (for a woman who still has her uterus For some women, hormone therapy may increase their or womb) can be used. chances of getting blood clots, heart attacks, strokes, breast cancer, and gall bladder disease. For a woman with a uterus, estrogen increases the chance of getting endometrial cancer (cancer of the uterine lining). Adding progestin lowers this risk. Menopause & Hormones

How long should I use hormone therapy for Has FDA approved other treatments for menopause symptoms? menopause? • You should talk to your doctor, nurse, or pharmacist. Yes. In 2013, FDA approved: • Treatment of menopausal symptoms should be • A non-hormonal treatment for moderate to severe decided with your healthcare provider, as there hot flashes associated with menopause. are many different FDA-approved hormones for • A medicine to treat moderate to severe dyspareunia treatment of the symptoms of menopause. (pain with sexual activity) due to vaginal changes Does it make a difference what form of that occur with menopause. hormones I use for menopause? Are herbs and other “natural” products Yes. FDA recommends that women use hormone useful in treating symptoms of menopause? therapies that are FDA-approved. FDA-approved At this time, FDA does not know if herbs or other hormone therapies are evaluated for safety and “natural” products are helpful or safe. effectiveness. Are compounded “bioidentical hormones” safer or more effective than FDA-approved Should I use estrogen just to prevent thin bones? hormone therapy for menopause? You can, but there are also other medicines and Many marketed products that are called “bioidentical things you can do to help your bones. Speak to your hormones” are compounded drugs, which are not healthcare provider. FDA-approved. FDA does not have evidence that Should I use hormone therapy to protect the compounded “bioidentical hormones” are safe and heart or prevent strokes? effective, or safer or more effective than FDA-approved No, do not use hormone therapy to prevent heart hormone therapy. attacks or strokes. FDA has approved drugs containing hormones that are identical to the hormones made naturally by women in Should I use hormone therapy to prevent their reproductive years. memory loss or Alzheimer’s disease? No, do not use hormone therapy to prevent memory Is the hormone estriol a “safer form of loss or Alzheimer’s disease. estrogen”? Do hormones protect against aging and wrinkles FDA does not have evidence that drugs containing or increase my sex drive? estriol are safe and effective, or are “safer forms Studies have not shown that hormone therapy of estrogen.” There are no FDA-approved drugs containing estriol. Marketed drugs that contain estriol prevents aging and wrinkles or increases sex drive. are compounded drugs, which are not FDA-approved.

For more information: FDA Office of Women’s Health www.fda.gov/menopause

2019