SEPT7 polyclonal antibody Gene Summary: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces Catalog Number: PAB11439 cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these Regulatory Status: For research use only (RUO) similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a Product Description: Goat polyclonal antibody raised structural component of the 10 nm filament which lies against synthetic peptide of SEPT7. inside the cytoplasmic membrane and is essential for cytokinesis. Although the exact function of this gene has Immunogen: A synthetic peptide corresponding to not yet been determined, its high similarity to yeast human SEPT7. CDC10 and the high conservative nature of eukaryotic cell cycle machinery suggest a similar role to that of its Sequence: C-DNNKNKGQLTKSP yeast counterpart. Alternative splicing results in two Host: Goat transcript variants encoding different isoforms. [provided by RefSeq] Theoretical MW (kDa): 50.7, 50.6 References: Reactivity: Human 1. Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by Applications: ELISA, WB-Ce SOCS7. Kremer BE, Adang LA, Macara IG. Cell. 2007 (See our web site product page for detailed applications Sep 7;130(5):837-50. information)
Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols
Form: Liquid
Purification: Antigen affinity purification
Concentration: 0.5 mg/mL
Recommend Usage: ELISA (1:32000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
Storage Buffer: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction: Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Entrez GeneID: 989
Gene Symbol: SEPT7
Gene Alias: CDC10, CDC3, Nbla02942, SEPT7A
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