Anti-EXOC7 monoclonal antibody, clone 80Y24G4 (CABT-B071) This product is for research use only and is not intended for diagnostic use.
PRODUCT INFORMATION
Specificity This antibody recognizes exocyst complex exo70 subunit. Reactive against Mouse and Rat.
Target EXOC7
Immunogen Recombinant protein corresponding to full-length rat brain exo70 subunit
Isotype IgG
Source/Host Mouse
Species Reactivity Mouse, Rat
Clone 80Y24G4
Purification Protein G affinity purified
Conjugate Unconjugated
Applications WB, ELISA, IF
Format Liquid
Concentration 1mg/ml
Size 100μg
Preservative None
Storage Store at 4°C
Ship Shipped cold packs
BACKGROUND
Introduction Exocyst complex (also known as the sec6/8 complex) is a multimeric complex that has been implicated to play a role in exocytosis. This complex is conserved from yeast to mammals and is composed of eight subunits (Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84). In the budding yeast Saccharomyces cerevisiae, mutations in these complex subunits promote
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved cytoplasmic accumulation of secretory vesicles and affects polarized growth. In cultured Drosophila and mammlian cells, disruption of exocyst subunit function has been found to decrease neurite outgrowth and Golgi-to-plasma membrane vesicle trafficking. Furthermore, a delay in neuronal induction was observed in mouse embryos with deletion of the sec8 gene, suggesting that the exocyst complex may play a role in cell differentiation and polarized growth.
Keywords EXOC7;exocyst complex component 7;EX070;EXO70;EXOC1;2-5-3p;Exo70p;YJL085W;exocyst complex component Exo70
GENE INFORMATION
Entrez Gene ID 23265
UniProt ID Q63HP7
45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]
Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved